Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

VN1R5 OXER1 DRD4 F2RL3 AVPR2 FFAR3 GPR42 MC1R GPR135 CASR S1PR2 OR8K3 TNFRSF11A TNFRSF10B PTGER1 S1PR1 S1PR5 TGFBR1 NPFFR2 ADRA2B KISS1R HMCN2 GLP1R PKD1 MTNR1B EDA2R

6.46e-1013539626GO:0004888
GeneOntologyMolecularFunctionG protein-coupled receptor activity

VN1R5 OXER1 DRD4 F2RL3 AVPR2 FFAR3 GPR42 MC1R GPR135 CASR S1PR2 OR8K3 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R GLP1R MTNR1B

6.03e-098849620GO:0004930
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

F2RL3 AVPR2 MC1R S1PR2 NPFFR2 KISS1R GLP1R

3.61e-06133967GO:0008528
GeneOntologyMolecularFunctionpeptide receptor activity

F2RL3 AVPR2 MC1R S1PR2 NPFFR2 KISS1R GLP1R

5.08e-06140967GO:0001653
GeneOntologyMolecularFunctionsphingosine-1-phosphate receptor activity

S1PR2 S1PR1 S1PR5

5.93e-068963GO:0038036
GeneOntologyMolecularFunctionbioactive lipid receptor activity

S1PR2 S1PR1 S1PR5

5.76e-0516963GO:0045125
GeneOntologyMolecularFunctiondeath receptor activity

TNFRSF11A TNFRSF10B EDA2R

1.35e-0421963GO:0005035
GeneOntologyMolecularFunctionepinephrine binding

DRD4 ADRA2B

3.39e-046962GO:0051379
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

OXER1 DRD4 AVPR2 FFAR3 GPR42 MC1R CASR S1PR2 PTGER1 S1PR1 S1PR5 ADRA2B GLP1R

7.71e-102869613GO:0007188
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

VN1R5 OXER1 DRD4 F2RL3 AVPR2 FFAR3 GPR42 MC1R GPR135 CASR S1PR2 OR8K3 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R GLP1R SLIT3 MTNR1B

1.36e-0613959621GO:0007186
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

OXER1 DRD4 FFAR3 GPR42 CASR S1PR1

3.02e-0686966GO:0007193
GeneOntologyBiologicalProcesspositive regulation of transmission of nerve impulse

FFAR3 GPR42 MTNR1B

2.70e-0513963GO:0051971
GeneOntologyBiologicalProcessadenylate cyclase-activating G protein-coupled receptor signaling pathway

MC1R S1PR2 PTGER1 S1PR1 S1PR5 ADRA2B GLP1R

3.11e-05191967GO:0007189
GeneOntologyBiologicalProcesssphingosine-1-phosphate receptor signaling pathway

S1PR2 S1PR1 S1PR5

4.27e-0515963GO:0003376
GeneOntologyBiologicalProcessregulation of neuronal action potential

FFAR3 GPR42 MTNR1B

4.27e-0515963GO:0098908
GeneOntologyBiologicalProcesspositive regulation of acute inflammatory response to non-antigenic stimulus

FFAR3 GPR42

6.41e-053962GO:0002879
GeneOntologyBiologicalProcesssphingolipid mediated signaling pathway

S1PR2 S1PR1 S1PR5

7.58e-0518963GO:0090520
GeneOntologyBiologicalProcessregulation of acute inflammatory response to non-antigenic stimulus

FFAR3 GPR42

1.28e-044962GO:0002877
GeneOntologyBiologicalProcesshydrogen peroxide biosynthetic process

ACOX1 DUOX1 DUOXA1

1.41e-0422963GO:0050665
GeneOntologyBiologicalProcessregulation of nervous system process

DRD4 FFAR3 GPR42 S1PR2 MTNR1B TMEM108

1.69e-04175966GO:0031644
GeneOntologyBiologicalProcessacute inflammatory response to non-antigenic stimulus

FFAR3 GPR42

2.12e-045962GO:0002525
GeneOntologyBiologicalProcessregulation of norepinephrine secretion

FFAR3 GPR42 ADRA2B

2.35e-0426963GO:0014061
GeneOntologyBiologicalProcessnorepinephrine secretion

FFAR3 GPR42 ADRA2B

2.94e-0428963GO:0048243
GeneOntologyBiologicalProcessregulation of transmission of nerve impulse

FFAR3 GPR42 MTNR1B

2.94e-0428963GO:0051969
GeneOntologyBiologicalProcesspositive regulation of neuronal action potential

FFAR3 GPR42

3.18e-046962GO:1904457
GeneOntologyCellularComponentcell surface

LRRC24 CASR TNFRSF11A TNFRSF10B TMPRSS11F ITGA7 ITGAE S1PR1 HCST TGFBR1 DUOX1 ADRA2B KISS1R PKD1 CHRD

1.78e-0411119715GO:0009986
DomainG_PROTEIN_RECEP_F1_1

VN1R5 OXER1 DRD4 F2RL3 AVPR2 FFAR3 GPR42 MC1R GPR135 S1PR2 OR8K3 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R MTNR1B

6.41e-096859318PS00237
DomainG_PROTEIN_RECEP_F1_2

VN1R5 OXER1 DRD4 F2RL3 AVPR2 FFAR3 GPR42 MC1R GPR135 S1PR2 OR8K3 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R MTNR1B

7.34e-096919318PS50262
DomainGPCR_Rhodpsn

VN1R5 OXER1 DRD4 F2RL3 AVPR2 FFAR3 GPR42 MC1R GPR135 S1PR2 OR8K3 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R MTNR1B

7.51e-096929318IPR000276
Domain7tm_1

OXER1 DRD4 F2RL3 AVPR2 FFAR3 GPR42 MC1R GPR135 S1PR2 OR8K3 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R MTNR1B

3.48e-086779317PF00001
DomainGPCR_Rhodpsn_7TM

OXER1 DRD4 F2RL3 AVPR2 FFAR3 MC1R GPR135 S1PR2 OR8K3 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R MTNR1B

1.83e-076709316IPR017452
DomainS1P_rcpt

S1PR2 S1PR1 S1PR5

1.19e-065933IPR004061
Domain7TM_GPCR_Srsx

DRD4 MC1R S1PR2 S1PR1 NPFFR2 ADRA2B MTNR1B

1.43e-06112937SM01381
DomainGPR40-rel_orph

FFAR3 GPR42

1.46e-044932IPR013312
DomainTNFR_c6

TNFRSF11A TNFRSF10B EDA2R

1.72e-0422933PF00020
DomainWSC

KREMEN1 PKD1

2.43e-045932SM00321
DomainWSC_carb-bd

KREMEN1 PKD1

2.43e-045932IPR002889
DomainWSC

KREMEN1 PKD1

2.43e-045932PF01822
DomainWSC

KREMEN1 PKD1

2.43e-045932PS51212
DomainTNFR

TNFRSF11A TNFRSF10B EDA2R

2.86e-0426933SM00208
DomainTNFR_NGFR_1

TNFRSF11A TNFRSF10B EDA2R

3.98e-0429933PS00652
DomainTNFR_NGFR_2

TNFRSF11A TNFRSF10B EDA2R

3.98e-0429933PS50050
DomainTNFR/NGFR_Cys_rich_reg

TNFRSF11A TNFRSF10B EDA2R

5.85e-0433933IPR001368
DomainERAP1-like_C_dom

TRHDE LVRN

6.74e-048932IPR024571
DomainERAP1_C

TRHDE LVRN

6.74e-048932PF11838
DomainIntegrin_alpha

ITGA7 ITGAE

1.31e-0311932PF00357
DomainPeptidase_M1

TRHDE LVRN

1.57e-0312932IPR001930
DomainPeptidase_M1

TRHDE LVRN

1.85e-0313932PF01433
DomainPeptidase_M1_N

TRHDE LVRN

1.85e-0313932IPR014782
DomainIntegrin_alpha_C_CS

ITGA7 ITGAE

2.81e-0316932IPR018184
DomainAa_trans

SLC38A7 SLC36A3

3.18e-0317932PF01490
DomainAA_transpt_TM

SLC38A7 SLC36A3

3.18e-0317932IPR013057
DomainEGF_CA

TENM2 HMCN2 SLIT3 DLK2

3.23e-03122934SM00179
DomainEGF-like_Ca-bd_dom

TENM2 HMCN2 SLIT3 DLK2

3.43e-03124934IPR001881
DomainIntegrin_alpha-2

ITGA7 ITGAE

3.56e-0318932IPR013649
DomainIntegrin_alpha2

ITGA7 ITGAE

3.56e-0318932PF08441
DomainIntegrin_alpha

ITGA7 ITGAE

3.56e-0318932IPR000413
DomainINTEGRIN_ALPHA

ITGA7 ITGAE

3.56e-0318932PS00242
DomainInt_alpha_beta-p

ITGA7 ITGAE

3.97e-0319932IPR013519
DomainInt_alpha

ITGA7 ITGAE

3.97e-0319932SM00191
DomainFG_GAP

ITGA7 ITGAE

5.31e-0322932PS51470
DomainFG-GAP

ITGA7 ITGAE

6.30e-0324932PF01839
DomainFG-GAP

ITGA7 ITGAE

6.30e-0324932IPR013517
DomainIntegrin_dom

ITGA7 ITGAE

6.83e-0325932IPR032695
PathwayWP_GPCRS_NONODORANT

DRD4 F2RL3 AVPR2 FFAR3 GPR42 MC1R CASR S1PR2 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R GLP1R MTNR1B

4.67e-142666516MM15843
PathwayREACTOME_GPCR_LIGAND_BINDING

DRD4 F2RL3 AVPR2 FFAR3 GPR42 MC1R CASR S1PR2 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R GLP1R MTNR1B

7.01e-114306516MM15160
PathwayREACTOME_GPCR_LIGAND_BINDING

OXER1 DRD4 F2RL3 AVPR2 FFAR3 MC1R CASR S1PR2 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R GLP1R MTNR1B

2.09e-104636516M507
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

OXER1 DRD4 F2RL3 AVPR2 FFAR3 MC1R S1PR2 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R MTNR1B

2.34e-103306514M18334
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

DRD4 F2RL3 AVPR2 MC1R S1PR2 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R GLP1R MTNR1B

2.59e-102726513M13380
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

DRD4 F2RL3 AVPR2 FFAR3 GPR42 MC1R S1PR2 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R MTNR1B

2.64e-103336514MM14963
PathwayREACTOME_SIGNALING_BY_GPCR

DRD4 F2RL3 AVPR2 FFAR3 GPR42 MC1R CASR S1PR2 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R GLP1R MTNR1B

2.50e-086466516MM14962
PathwayREACTOME_SIGNALING_BY_GPCR

OXER1 DRD4 F2RL3 AVPR2 FFAR3 MC1R CASR S1PR2 PTGER1 S1PR1 S1PR5 NPFFR2 ADRA2B KISS1R GLP1R MTNR1B

7.94e-087026516M746
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

DRD4 F2RL3 AVPR2 FFAR3 GPR42 MC1R PTGER1 NPFFR2 ADRA2B MTNR1B

2.81e-072606510M39397
PathwayWP_GPCRS_SMALL_LIGAND

S1PR2 PTGER1 S1PR1 MTNR1B

1.20e-0618654MM15858
PathwayWP_SMALL_LIGAND_GPCRS

S1PR2 PTGER1 S1PR1 MTNR1B

1.51e-0619654M39728
PathwayWP_GPCRS_OTHER

VN1R5 CASR S1PR2 S1PR1 S1PR5 MTNR1B

5.09e-0696656MM15939
PathwayREACTOME_LYSOSPHINGOLIPID_AND_LPA_RECEPTORS

S1PR2 S1PR1 S1PR5

3.28e-0514653M27331
PathwayREACTOME_LYSOSPHINGOLIPID_AND_LPA_RECEPTORS

S1PR2 S1PR1 S1PR5

3.28e-0514653MM15062
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

F2RL3 FFAR3 GPR42 CASR PTGER1 NPFFR2 KISS1R

4.93e-05210657MM15043
PathwayPID_S1P_META_PATHWAY

S1PR2 S1PR1 S1PR5

1.17e-0421653M155
PathwayWP_SIGNAL_TRANSDUCTION_OF_S1P_RECEPTOR

S1PR2 S1PR1 S1PR5

1.55e-0423653MM15952
PathwayWP_S1P_RECEPTOR_SIGNAL_TRANSDUCTION

S1PR2 S1PR1 S1PR5

2.00e-0425653M39384
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

DRD4 F2RL3 AVPR2 MC1R PTGER1 ADRA2B

2.11e-04186656MM15994
PathwayWP_SPHINGOLIPID_METABOLISM_IN_SENESCENCE

S1PR2 S1PR1 S1PR5

2.82e-0428653M42536
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

F2RL3 FFAR3 CASR PTGER1 NPFFR2 KISS1R

4.81e-04217656M18437
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

OXER1 DRD4 CASR S1PR2 S1PR5 ADRA2B MTNR1B

5.86e-04314657M600
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

TRHDE DNHD1 TSPAN18 PIGG TNFRSF10B PCDH12 ITGA7 PIGU IL23A HCST C16orf89 SLIT3 PRRT3 DLK2 CHRD CRB3 TMEM108 EDA2R C16orf54

2.86e-11985971912975309
Pubmed

Dissociation of heterotrimeric g proteins in cells.

OXER1 DRD4 CASR S1PR2 S1PR1 S1PR5 GLP1R MTNR1B

4.12e-0817997818577758
Pubmed

Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1P) receptors, S1P(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3.

S1PR2 S1PR1 S1PR5

8.40e-08497312006579
Pubmed

Sphingosine-1-phosphate receptor 2.

S1PR2 S1PR1 S1PR5

2.09e-07597323879641
Pubmed

Sphingosine 1-Phoshpate Receptors are Located in Synapses and Control Spontaneous Activity of Mouse Neurons in Culture.

S1PR2 S1PR1 S1PR5

2.09e-07597335781853
Pubmed

Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3.

S1PR2 S1PR1 S1PR5

4.18e-07697311443127
Pubmed

The role of sphingosine kinase isoforms and receptors S1P1, S1P2, S1P3, and S1P5 in primary, secondary, and recurrent glioblastomas.

S1PR2 S1PR1 S1PR5

4.18e-07697324903384
Pubmed

Differential expression of sphingosine-1-phosphate receptors 1-5 in the developing nervous system.

S1PR2 S1PR1 S1PR5

7.30e-07797319161225
Pubmed

Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p(1) in neurogenesis and s1p(1-3) in angiogenesis.

S1PR2 S1PR1 S1PR5

2.49e-061097312401212
Pubmed

Sphingosine-1-phosphate inhibits cell migration and endothelial to mesenchymal cell transformation during cardiac development.

S1PR2 S1PR1 S1PR5

2.49e-061097316434032
Pubmed

Vascular function and sphingosine-1-phosphate regulate development of the dorsal pancreatic mesenchyme.

S1PR2 S1PR1 S1PR5

2.49e-061097315689381
Pubmed

Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions.

S1PR1 TGFBR1 CLDN5

3.41e-061197322498737
Pubmed

Dynamic regulation of sphingosine-1-phosphate homeostasis during development of mouse metanephric kidney.

S1PR2 S1PR1 S1PR5

3.41e-061197319073640
Pubmed

The identification of novel proteins that interact with the GLP-1 receptor and restrain its activity.

CEND1 PIGG GLP1R TMEM147

4.34e-063997423864651
Pubmed

Pancreatic islet and progenitor cell surface markers with cell sorting potential.

TGFBR1 PRRT3 CRB3 TMEM108 CLDN5

4.43e-068697521947380
Pubmed

Expression patterns of the lysophospholipid receptor genes during mouse early development.

S1PR2 S1PR1 S1PR5

5.89e-061397318924241
Pubmed

Stable association between G alpha(q) and phospholipase C beta 1 in living cells.

FFAR3 CASR PTGER1 NPFFR2 KISS1R

7.22e-069597516754659
Pubmed

Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia.

FFAR3 GPR42

7.70e-06297225637492
Pubmed

IL-23 promotes osteoclast formation by up-regulation of receptor activator of NF-kappaB (RANK) expression in myeloid precursor cells.

TNFRSF11A IL23A

7.70e-06297218958885
Pubmed

Selective tracking of FFAR3-expressing neurons supports receptor coupling to N-type calcium channels in mouse sympathetic neurons.

FFAR3 GPR42

7.70e-06297230478340
Pubmed

Role of sphingosine-1-phosphate receptor 1 and sphingosine-1-phosphate receptor 2 in hyperglycemia-induced endothelial cell dysfunction.

S1PR2 S1PR1

7.70e-06297225673082
Pubmed

3-(4-Hydroxy-3-methoxyphenyl) propionic acid contributes to improved hepatic lipid metabolism via GPR41.

FFAR3 GPR42

7.70e-06297238040866
Pubmed

Genetic Inactivation of Free Fatty Acid Receptor 3 Impedes Behavioral Deficits and Pathological Hallmarks in the APPswe Alzheimer's Disease Mouse Model.

FFAR3 GPR42

7.70e-06297235408893
Pubmed

FFAR3 modulates insulin secretion and global gene expression in mouse islets.

FFAR3 GPR42

7.70e-06297226091414
Pubmed

Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation.

DUOX1 DUOXA1

7.70e-06297232929281
Pubmed

GPR41 modulates insulin secretion and gene expression in pancreatic β-cells and modifies metabolic homeostasis in fed and fasting states.

FFAR3 GPR42

7.70e-06297227550964
Pubmed

Intestinal FFA3 mediates obesogenic effects in mice on a Western diet.

FFAR3 GPR42

7.70e-06297235858247
Pubmed

Changes in S1P1 and S1P2 expression during embryonal development and primitive endoderm differentiation of F9 cells.

S1PR2 S1PR1

7.70e-06297216631609
Pubmed

Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms.

FFAR3 GPR42

7.70e-06297222506074
Pubmed

Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease.

TGFBR1 PKD1

7.70e-06297227020852
Pubmed

Free fatty acid receptor 3 differentially contributes to β-cell compensation under high-fat diet and streptozotocin stress.

FFAR3 GPR42

7.70e-06297232073900
Pubmed

FTY720 modulates human oligodendrocyte progenitor process extension and survival.

S1PR1 S1PR5

7.70e-06297217918267
Pubmed

Immunohistochemical detection of sphingosine-1-phosphate receptor 1 and 5 in human multiple sclerosis lesions.

S1PR1 S1PR5

7.70e-06297223551178
Pubmed

The effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41.

FFAR3 GPR42

7.70e-06297224748202
Pubmed

The Cognitive Improvement and Alleviation of Brain Hypermetabolism Caused by FFAR3 Ablation in Tg2576 Mice Is Persistent under Diet-Induced Obesity.

FFAR3 GPR42

7.70e-06297236362376
Pubmed

S1P Stimulates Erythropoietin Production in Mouse Renal Interstitial Fibroblasts by S1P1 and S1P3 Receptor Activation and HIF-2α Stabilization.

S1PR2 S1PR1

7.70e-06297234502385
Pubmed

Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference.

S1PR1 S1PR5

7.70e-06297215489955
Pubmed

Structures of human dual oxidase 1 complex in low-calcium and high-calcium states.

DUOX1 DUOXA1

7.70e-06297233420071
Pubmed

Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids.

FFAR3 GPR42

7.70e-06297220399779
Pubmed

Sequence polymorphisms provide a common consensus sequence for GPR41 and GPR42.

FFAR3 GPR42

7.70e-06297219630535
Pubmed

Differential activation of receptors and signal pathways upon stimulation by different doses of sphingosine-1-phosphate in endothelial cells.

S1PR2 S1PR1

7.70e-06297225557733
Pubmed

Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.

S1PR2 S1PR1

7.70e-06297218323526
Pubmed

Cell type-specific localization of human cardiac S1P receptors.

S1PR2 S1PR1

7.70e-06297211967277
Pubmed

Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content.

FFAR3 GPR42

7.70e-06297223110765
Pubmed

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.

FFAR3 GPR42

7.70e-06297226522986
Pubmed

Sphingosine 1-phosphate (S1P) receptors 1 and 2 coordinately induce mesenchymal cell migration through S1P activation of complementary kinase pathways.

S1PR2 S1PR1

7.70e-06297223300082
Pubmed

Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.

FFAR3 GPR42

7.70e-06297214722361
Pubmed

Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41.

FFAR3 GPR42

7.70e-06297227664183
Pubmed

Human GPR42 is a transcribed multisite variant that exhibits copy number polymorphism and is functional when heterologously expressed.

FFAR3 GPR42

7.70e-06297226260360
Pubmed

G protein coupled receptor 41 regulates fibroblast activation in pulmonary fibrosis via Gαi/o and downstream Smad2/3 and ERK1/2 phosphorylation.

FFAR3 GPR42

7.70e-06297237019194
Pubmed

Lysophospholipid receptor nomenclature review: IUPHAR Review 8.

S1PR2 S1PR1 S1PR5

9.34e-061597324602016
Pubmed

Microbiota modulate sympathetic neurons via a gut-brain circuit.

FFAR3 GPR42 GLP1R

9.34e-061597332641826
Pubmed

Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis.

S1PR2 TNFRSF11A S1PR1

1.66e-051897328709801
Pubmed

Differential expression of S1P receptor subtypes in human bladder transitional cell carcinoma.

S1PR2 S1PR1

2.31e-05397230712233
Pubmed

Short-chain fatty acid receptor GPR41-mediated activation of sympathetic neurons involves synapsin 2b phosphorylation.

FFAR3 GPR42

2.31e-05397222673524
Pubmed

A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis.

S1PR2 S1PR1

2.31e-05397223148237
Pubmed

Role of sphingosine kinase and sphingosine-1-phosphate receptor in the liver pathology of mice infected with Plasmodium berghei ANKA.

S1PR2 S1PR1

2.31e-05397235333897
Pubmed

Differential expression of sphingosine-1-phosphate receptors in abdominal aortic aneurysms.

S1PR2 S1PR1

2.31e-05397222547907
Pubmed

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.

FFAR3 GPR42

2.31e-05397212496283
Pubmed

Epidermal growth factor-induced hydrogen peroxide production is mediated by dual oxidase 1.

DUOX1 DUOXA1

2.31e-05397227262981
Pubmed

[Regulation of Rho family G proteins and cell motility by the Edg family of sphingosin 1-phosphate receptors].

S1PR2 S1PR1

2.31e-05397211915348
Pubmed

Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice.

FFAR3 GPR42

2.31e-05397223665276
Pubmed

Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer.

FFAR3 GPR42

2.31e-05397234210970
Pubmed

Sphingosine-1-phosphate and its receptors in anti-neutrophil cytoplasmic antibody-associated vasculitis.

S1PR2 S1PR1

2.31e-05397228206609
Pubmed

Dietary short-chain fatty acid intake improves the hepatic metabolic condition via FFAR3.

FFAR3 GPR42

2.31e-05397231719611
Pubmed

S1P1 receptor localization confers selectivity for Gi-mediated cAMP and contractile responses.

S1PR2 S1PR1

2.31e-05397218296752
Pubmed

Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43.

FFAR3 GPR42

2.31e-05397216123168
Pubmed

GPR41 gene expression is mediated by internal ribosome entry site (IRES)-dependent translation of bicistronic mRNA encoding GPR40 and GPR41 proteins.

FFAR3 GPR42

2.31e-05397222493486
Pubmed

Opposing Roles of Sphingosine 1-Phosphate Receptors 1 and 2 in Fat Deposition and Glucose Tolerance in Obese Male Mice.

S1PR2 S1PR1

2.31e-05397236690339
Pubmed

Dual oxidase regulates neutrophil recruitment in allergic airways.

DUOX1 DUOXA1

2.31e-05397223770197
Pubmed

Differential effects of sphingosine 1-phosphate receptors on airway and vascular barrier function in the murine lung.

S1PR2 S1PR1

2.31e-05397219749179
Pubmed

Sphingosine 1-phosphate (S1P)/S1P receptors are involved in human liver fibrosis by action on hepatic myofibroblasts motility.

S1PR2 S1PR1

2.31e-05397221145832
Pubmed

Cyclin G2 upregulation impairs migration, invasion, and network formation through RNF123/Dvl2/JNK signaling in the trophoblast cell line HTR8/SVneo, a possible role in preeclampsia.

CCNG2 RNF123

2.31e-05397233205477
Pubmed

CD4 T cell sphingosine 1-phosphate receptor (S1PR)1 and S1PR4 and endothelial S1PR2 regulate afferent lymphatic migration.

S1PR2 S1PR1

2.31e-05397230877143
Pubmed

Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3.

FFAR3 GPR42

2.31e-05397223066016
Pubmed

Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes.

FFAR3 GPR42

2.31e-05397225581519
Pubmed

Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2.

FFAR3 GPR42

2.31e-05397222190648
Pubmed

Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells.

FFAR3 GPR42

2.31e-05397231272808
Pubmed

GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes.

FFAR3 GPR42

2.31e-05397223885020
Pubmed

Sphingosine 1-phosphate regulates IL-8 expression and secretion via S1PR1 and S1PR2 receptors-mediated signaling in extravillous trophoblast derived HTR-8/SVneo cells.

S1PR2 S1PR1

2.31e-05397226321412
Pubmed

Sphingosine 1-phosphate and human ether-a'-go-go-related gene potassium channels modulate migration in human anaplastic thyroid cancer cells.

S1PR2 S1PR1

2.31e-05397222889737
Pubmed

Dietary Fiber Confers Protection against Flu by Shaping Ly6c- Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism.

FFAR3 GPR42

2.31e-05397229768180
Pubmed

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41.

FFAR3 GPR42

2.31e-05397218931303
Pubmed

GPR41 and GPR43 regulate CD8+ T cell priming during herpes simplex virus type 1 infection.

FFAR3 GPR42

2.31e-05397238524121
Pubmed

Abnormalities in microbiota/butyrate/FFAR3 signaling in aging gut impair brain function.

FFAR3 GPR42

2.31e-05397238329121
Pubmed

Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5.

S1PR2 S1PR1

2.31e-05397210383399
Pubmed

Essential roles of IL-12 and dendritic cells but not IL-23 and macrophages in lupus-like diseases initiated by cell surface HSP gp96.

HSP90B1 IL23A

2.31e-05397217294405
Pubmed

Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking, and activity of the nonselective cation channel TRPC6.

ACOX1 TNFRSF10B ALG5 TMEM147

2.98e-056397431266804
Pubmed

Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.

PIEZO1 HCST SLC7A1 PRRT3 C16orf54

3.56e-0513297526439863
Pubmed

Quantitative trait loci for obesity- and diabetes-related traits and their dietary responses to high-fat feeding in LGXSM recombinant inbred mouse strains.

AVPR2 MC1R TNFRSF11A

4.08e-052497315561968
Pubmed

Endothelial sphingosine 1-phosphate receptors promote vascular normalization and antitumor therapy.

S1PR2 S1PR1

4.60e-05497231988136
Pubmed

Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation.

FFAR3 GPR42

4.60e-05497223401498
Pubmed

Sphingosine 1-phosphate stimulates proliferation and migration of satellite cells: role of S1P receptors.

S1PR2 S1PR1

4.60e-05497222178384
Pubmed

Interaction of integrin β4 with S1P receptors in S1P- and HGF-induced endothelial barrier enhancement.

S1PR2 S1PR1

4.60e-05497224851274
Pubmed

Orphan GPR61, GPR62 and GPR135 receptors and the melatonin MT2 receptor reciprocally modulate their signaling functions.

GPR135 MTNR1B

4.60e-05497228827538
Pubmed

Sphingosine 1-phosphate: a ligand for the EDG-1 family of G-protein-coupled receptors.

S1PR2 S1PR1

4.60e-05497210818441
Pubmed

A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1.

FFAR3 GPR42

4.60e-0549729344866
Pubmed

Quality control for unfolded proteins at the plasma membrane.

DRD4 AVPR2

4.60e-05497220974815
Pubmed

Sphingosine-1-phosphate receptor expression and signaling correlate with uterine prostaglandin-endoperoxide synthase 2 expression and angiogenesis during early pregnancy.

S1PR2 S1PR1

4.60e-05497216319286
Pubmed

Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41).

FFAR3 GPR42

4.60e-05497221518883
InteractionPIGW interactions

AVPR2 SPPL2B SLC7A1 RNF123

6.13e-0626944int:PIGW
InteractionCLRN2 interactions

TRHDE SLC30A1 TMEM179B TMEM62 CLDN5

2.82e-0576945int:CLRN2
InteractionPIGM interactions

DRD4 AVPR2 SPPL2B RNF123

3.57e-0540944int:PIGM
InteractionTMEM14A interactions

TMEM179B SLC7A1 RNF123 MTNR1B

4.34e-0542944int:TMEM14A
InteractionTSPAN15 interactions

SCAMP1 PIEZO1 S1PR2 PIGG PIGU S1PR1 SLC7A1 ALG5

4.50e-05276948int:TSPAN15
InteractionMFSD5 interactions

AVPR2 GPR42 SPPL2B TMEM179B GLP1R

5.13e-0586945int:MFSD5
InteractionKLRC2 interactions

PIGG PIGU S1PR5 TMEM62

6.23e-0546944int:KLRC2
InteractionTNPO2 interactions

DRD4 AVPR2 S1PR1 HCST RNF123 DLK2 TMEM108

8.61e-05224947int:TNPO2
Cytoband19q13.1

FFAR3 GPR42 HCST TMEM147

5.88e-065597419q13.1
GeneFamilySphingosine 1-phosphate receptors|CD molecules

S1PR2 S1PR1 S1PR5

4.41e-075653206
GeneFamilyCD molecules|Tumor necrosis factor receptor superfamily|Death inducing signaling complex

TNFRSF11A TNFRSF10B EDA2R

1.52e-0429653782
GeneFamilyCD molecules|Integrin alpha subunits

ITGA7 ITGAE

1.88e-03186521160
GeneFamilyGlycosyl transferases group 1 domain containing|Phosphatidylinositol glycan anchor biosynthesis

PIGG PIGU

2.56e-0321652680
ToppCellEndothelial-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

TSPAN18 F2RL3 TNFRSF11A PCDH12 S1PR1 DLK2 CLDN5

9.76e-0817197707ff7059071da83da1d8f266a586573920d75b58
ToppCellfacs-Marrow-T_cells-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S HSP90B1 ERO1B PLPP5 ALG5 CRB3 TMEM82

1.10e-071749773b1ee39e85e5f0d6b17fb3051dbfae66cb2be6ee
ToppCellEndothelial-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

F2RL3 AVPR2 TNFRSF11A PCDH12 S1PR1 CLDN5

1.91e-061699768889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCellEndothelial-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

TSPAN18 F2RL3 TNFRSF11A PCDH12 S1PR1 CLDN5

2.12e-061729768a527dff06d841a86c7eb04a1dd9630787294da4
ToppCellfacs-Marrow-T_cells-18m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S HSP90B1 ERO1B PLPP5 ALG5 CRB3

2.34e-061759764be01bf30331162f1998216fb2871a4e626dc440
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-Late_cap|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CACNA1S TSPAN18 F2RL3 AVPR2 PCDH12 CLDN5

3.03e-061839763e69cc605f166a1f04e3d077935f7cfd806f1ffd
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S HSP90B1 TMEM150A ERO1B PLPP5 IL23A

3.23e-06185976ff95a45b7cb782961bb8f008b6b507af2d4cb8b7
ToppCellEndothelial-B|World / lung cells shred on cell class, cell subclass, sample id

TSPAN18 F2RL3 TNFRSF11A PCDH12 S1PR1 CLDN5

3.54e-061889765959a88728812a5f4cbfa54eddc7a73ccbaa2f68
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

F2RL3 AVPR2 PCDH12 S1PR1 DLK2 CLDN5

3.54e-06188976524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

F2RL3 AVPR2 PCDH12 S1PR1 DLK2 CLDN5

3.54e-06188976d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Lymphatic|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

TSPAN18 F2RL3 PCDH12 S1PR1 DLK2 CLDN5

3.76e-061909768d6ec2fc0af19a5cb16fff34f8b131b71b33d45f
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1S ITGA7 S1PR5 ADRA2B GLP1R SLIT3

3.76e-06190976a7f6c38bbf451f166febb21e6719d4afced4035e
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

VPS50 S1PR1 TGFBR1 SLC7A1 RNF123 PRRT3

3.88e-0619197639ef8e1d7cc3ebb11717e8a55501515e3b72b177
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1S ITGA7 S1PR5 ADRA2B GLP1R SLIT3

4.00e-061929765995bae840c0b3f420288f557634d0ae9a12a6ae
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TSPAN18 F2RL3 TNFRSF11A PCDH12 S1PR1 CLDN5

5.05e-06200976f99d0d3f51b4893fa7898c5b435494358a654cbd
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TSPAN18 F2RL3 TNFRSF11A PCDH12 S1PR1 CLDN5

5.05e-06200976e65d4ae3d48f68c12edd5dc2c2f4e25e4acfadf1
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Lymphatic|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

TSPAN18 F2RL3 TNFRSF11A PCDH12 S1PR1 CLDN5

5.05e-062009764ec8e30dd241d83a1bba1c5967b6a4656afbfafd
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RANBP6 GLP1R SERPING1 SLC36A3 VSTM5

1.30e-05138975a88c3ae56b0af60f6e87cabade4f21e2bbb336f2
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-3|TCGA-Colorectal / Sample_Type by Project: Shred V9

DRD4 FFAR3 PTGER1 S1PR5 SAC3D1

2.34e-05156975b464871ad7c8ce0d58013a27996639eac1e526d8
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN18 PCDH12 S1PR1 GLP1R CLDN5

2.41e-05157975b6ecf1d8c6a465ff31cbc181e00ea88b76b38e19
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN18 PCDH12 S1PR1 GLP1R CLDN5

2.41e-0515797501ad5cbaf91010e79216e1fb37b7b890618c5f28
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B1|367C / Donor, Lineage, Cell class and subclass (all cells)

VPS50 S1PR5 SLC7A1 RNF123 PRRT3

2.72e-05161975f470b662566131dfe69a2fd01186ac8491196396
ToppCellEndothelial-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

TSPAN18 F2RL3 PCDH12 S1PR1 CLDN5

3.06e-05165975b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCellEndothelial-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

TSPAN18 F2RL3 TNFRSF11A PCDH12 CLDN5

3.15e-05166975c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCellEndothelial-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

TSPAN18 PCDH12 S1PR1 DLK2 CLDN5

3.25e-051679756a03d16165e0b003092c39972928981abd4a75aa
ToppCellP28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DNHD1 C16orf89 TMEM62 KISS1R CHRD

3.34e-051689758c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRHDE LRRC24 CEND1 TMEM108 IGLON5

3.44e-05169975606aa4ff25380d9470ec116ca86cd20f8b19587a
ToppCellEndothelial-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

TSPAN18 TNFRSF11A PCDH12 S1PR1 CLDN5

3.44e-0516997595c617143e1fbdd1d55a93ffdcc210e0be37cf2f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRHDE LRRC24 CEND1 TMEM108 IGLON5

3.44e-05169975052aae2af5446a0de071d5dda5381b0b9a0ed54d
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

F2RL3 TNFRSF11A PCDH12 S1PR1 CLDN5

3.74e-05172975d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCellfacs-Marrow-B-cells-24m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S TMEM150A ERO1B PLPP5 CRB3

3.74e-0517297565b8935a972bf00b7a10dc2d442128fc0ed78bcb
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

F2RL3 GPR135 HCST DLK2 SLC36A3

3.84e-0517397515a77f6aac968b7a1afea4f60aedbb95b9d0f765
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

F2RL3 S1PR1 HCST GLP1R SLC36A3

3.84e-05173975da0f1461643294f92e20b5e456a50211a2780a91
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH12 ITGA7 S1PR1 C16orf89 C16orf54

4.06e-05175975c36b4526970db9ccfbe2c70b00961fab9f13b133
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH12 ITGA7 S1PR1 C16orf89 C16orf54

4.06e-05175975c1e082538f31b5c98ac63f71dcca4a1211a14708
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH12 ITGA7 S1PR1 C16orf89 C16orf54

4.06e-051759752f9b5bdf8a62e8e99d1c4f677a8e5525bfd3b4ce
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S TMEM150A ERO1B PLPP5 CRB3

4.17e-051769752e9073166da4d9fae70ba4f3fdcad35523caf7cd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA7 C2CD2 ADRA2B DUOXA1 SLIT3

4.28e-051779754943d040eee0f9dceaddc7498171281d170e271f
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S ERO1B PLPP5 ALG5 IGLON5

4.28e-0517797541cbb2c109eaa7be366fc0510cce64abc06837b4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA7 C2CD2 ADRA2B DUOXA1 SLIT3

4.28e-051779753f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIEZO1 TNFRSF11A S1PR1 SLC7A1 CLDN5

4.52e-05179975abc6797bd3884aa75dca58fcb2523ee321243ab1
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIEZO1 TNFRSF11A S1PR1 SLC7A1 CLDN5

4.52e-051799750b996d6e881f31e6b80d359f7caac70ecdeb9982
ToppCellEndothelial-A-HP_01|World / lung cells shred on cell class, cell subclass, sample id

TSPAN18 F2RL3 PCDH12 S1PR1 CLDN5

4.64e-051809754c3376169770ee9f9283daae44c17f35e46bfd19
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1S ITGA7 ADRA2B GLP1R SLIT3

4.64e-051809754fb95ed39508bede5472dd36aeabe91b33631726
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S TMEM150A ERO1B PLPP5 CRB3

4.76e-0518197597022416d0f5a5ba9c9bd5e70ce95cf4cb19af89
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

TSPAN18 F2RL3 AVPR2 PCDH12 CLDN5

4.89e-05182975d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCellE12.5-Endothelial-capillary_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

F2RL3 PCDH12 S1PR1 C16orf89 CLDN5

5.28e-05185975e005d3c01a908157f780bbc1d53dd2ed814a39d2
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S TMEM150A ERO1B PLPP5 CRB3

5.28e-05185975238938a4682b44e88a30b86b13af4feeabe9553d
ToppCelldroplet-Thymus-nan-24m-Myeloid-Plasma_cells_and_B_cells|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S TMEM150A ERO1B PLPP5 CRB3

5.28e-05185975e583f6601f9ed79b0b23d2f9426a4ba8b969230b
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LVRN TSPAN18 F2RL3 PCDH12 CLDN5

5.28e-05185975a987dbf6adf533c5f8a0a8a465a6c8e67e0ffcc8
ToppCellE12.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

F2RL3 PCDH12 S1PR1 C16orf89 CLDN5

5.28e-051859750bccc424d0466f7f82baa00127c733640a2d50fb
ToppCellEndoth-Lymph|World / shred by cell class for parenchyma

F2RL3 TNFRSF11A PCDH12 DLK2 CLDN5

5.28e-0518597597a6c4cd00684d4085d36ef32f7dbb99563ed357
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN18 PCDH12 DLK2 SERPING1 CLDN5

5.42e-0518697530dd4164c101006c8d95922d89652b82dbe4b5ea
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN18 PCDH12 DLK2 SERPING1 CLDN5

5.42e-05186975eeacf59a9e6bf1c9fd59b6b13d35e8abae228cf0
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

TSPAN18 F2RL3 PCDH12 HMCN2 CLDN5

5.42e-051869752e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell356C-Endothelial_cells-Endothelial-E|356C / Donor, Lineage, Cell class and subclass (all cells)

TSPAN18 F2RL3 PCDH12 HMCN2 CLDN5

5.42e-05186975c3449e54454009973818fc1101933c6f0168258c
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TSPAN18 AVPR2 PCDH12 HMCN2 CLDN5

5.42e-05186975a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1S ITGA7 S1PR5 ADRA2B SLIT3

5.56e-05187975d52f7bc0afcdc366b20d199ab33c4ec60ed22a68
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LVRN DUOX1 DUOXA1 SLIT3 SERPING1

5.56e-051879750d4b7da81036c2aa678654b9fe49c939d08fcd9b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA7 C2CD2 ADRA2B DUOXA1 SLIT3

5.56e-05187975ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA7 C2CD2 ADRA2B DUOXA1 SLIT3

5.56e-05187975530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellEndothelial-A-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

TSPAN18 F2RL3 PCDH12 S1PR1 CLDN5

5.56e-05187975febe0b99a6a815ce687160a0e7af55228b1d5beb
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

TSPAN18 F2RL3 AVPR2 PCDH12 CLDN5

5.56e-05187975be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL3 PCDH12 S1PR1 C16orf89 CLDN5

5.70e-0518897551c6796a9488c056a10d048082015342c2e037f9
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL3 PCDH12 S1PR1 C16orf89 CLDN5

5.70e-05188975b651024d58ed1bcfe0d80b21755f8bf709eda81f
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA7 S1PR1 C16orf89 ADRA2B SLIT3

5.70e-05188975da862ea3c74f42d0dbae38b09211a45c593d477e
ToppCelldroplet-Spleen-nan-21m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S HSP90B1 TMEM150A ERO1B PLPP5

5.70e-0518897570184b14160b71a1fecd7f195e5a16c5937738a2
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA7 S1PR1 C16orf89 ADRA2B SLIT3

5.70e-05188975b82a7667ef74a05e8bc744f6c090a7cc7b8efe32
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1S ITGA7 S1PR5 GLP1R SLIT3

5.70e-05188975c2321a3a1d9603f8b4b4fc09707eb32ec1e04f3f
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA7 S1PR1 C16orf89 ADRA2B SLIT3

5.70e-0518897519672d284fe89c9c3c7697514ca1f659329c34f4
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TSPAN18 F2RL3 TNFRSF11A PCDH12 SLC7A1

5.85e-051899750d18ea72bd58d32a8ab9a61cf97f5786642f804b
ToppCelldroplet-Mammary_Gland-nan-3m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFRSF11A TNFRSF10B S1PR1 C16orf89 CLDN5

5.85e-051899751d4ad307c0606957dd7bf8da84450e5193cf4a50
ToppCelldroplet-Mammary_Gland-nan-3m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFRSF11A TNFRSF10B S1PR1 C16orf89 CLDN5

5.85e-05189975b952026044d5f6c0adce60cf24f6e0199e6f8757
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN18 F2RL3 PCDH12 S1PR1 CLDN5

5.85e-05189975a34f008dfcee4012977bbc5b60de6f0329ca2f65
ToppCelldroplet-Mammary_Gland-nan-3m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFRSF11A TNFRSF10B S1PR1 C16orf89 CLDN5

5.85e-0518997525781edbd08c6e413740b796ecc8ba1934bd3aa5
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B1|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

VPS50 S1PR1 SLC7A1 RNF123 PRRT3

5.99e-051909752434b8ad2976eab7d9147012c28454ab29670709
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1S ITGA7 S1PR5 ADRA2B SLIT3

6.15e-05191975239c1e68eb1cbe3e137a99fbd6eeb8d64c919ffd
ToppCellEC|World / Lineage and Cell class

TSPAN18 PCDH12 S1PR1 C16orf89 CLDN5

6.30e-05192975478866dd5b0d6ff3a76d07a17c4b5989dd7a27bb
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC30A1 S1PR1 C16orf89 SLC7A1 CLDN5

6.30e-051929759ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC30A1 S1PR1 C16orf89 SLC7A1 CLDN5

6.30e-05192975a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC30A1 S1PR1 C16orf89 SLC7A1 CLDN5

6.30e-0519297566defad13bd8e79319741e43ddb056841710b1d7
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN18 PCDH12 S1PR1 C16orf89 SLIT3

6.46e-0519397595e64b9580d30c28702639a043a8b72ce1cadeb6
ToppCellLAM-Endothelial-LymEndo|LAM / Condition, Lineage and Cell class

TSPAN18 F2RL3 PCDH12 S1PR1 CLDN5

6.46e-0519397568eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC30A1 S1PR1 C16orf89 SLC7A1 CLDN5

6.46e-05193975e4b440d50ae7391b26924778be6d9d53e0692449
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC30A1 S1PR1 C16orf89 SLC7A1 CLDN5

6.46e-05193975e523dc5751f6fdcd4fc1a62b1eecd43f6ae79da9
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERO1B C16orf89 ADRA2B CRB3 VSTM5

6.46e-05193975c5925b3b5d19098e3987789d68a493d7fd548ac9
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC30A1 S1PR1 C16orf89 SLC7A1 CLDN5

6.46e-051939751772f2ac217727de63c4a9303881b3a19a6bb0f0
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERO1B C16orf89 ADRA2B CRB3 VSTM5

6.46e-051939756905de261d90dfe3dd2c2cf5b2e26afb2bcc3d5b
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERO1B C16orf89 ADRA2B CRB3 VSTM5

6.46e-05193975f73630725f093c646bdaf178c39505c04a16e2c6
ToppCellEndothelial-A-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

TSPAN18 PCDH12 S1PR1 ADRA2B CLDN5

6.61e-05194975e656ac5539e59e321b46706cb8cc423b2c3358a0
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSPAN18 PCDH12 SLC30A1 S1PR1 CLDN5

6.61e-051949758deeb3e00237e3d9ad5a1457cd0061576421b9e9
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSPAN18 PCDH12 SLC30A1 S1PR1 CLDN5

6.61e-05194975b81801fb16e8bd0d6083fe32866051d3c60f3dc7
ToppCellLAM-Endothelial|LAM / Condition, Lineage and Cell class

TSPAN18 F2RL3 PCDH12 S1PR1 CLDN5

6.61e-051949751241e3e75414b619abc9431627619f5c194ec930
ToppCelldroplet-Spleen-SPLEEN-30m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S HSP90B1 TMEM150A ERO1B PLPP5

6.78e-05195975f9a90cd7b4e99a0947fdb3645f7787d02b0f7ca0
ToppCellASK440-Endothelial-Endothelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

TSPAN18 F2RL3 PCDH12 S1PR1 CLDN5

6.78e-05195975304f0dc91bb57e98b0ca31d6bfb3ff9364e4da56
ToppCell367C-Endothelial_cells-Endothelial-E-|367C / Donor, Lineage, Cell class and subclass (all cells)

TSPAN18 F2RL3 PCDH12 S1PR1 CLDN5

6.78e-0519597565fc50e3818e902028fc4226070fa57609c66b9c
ToppCellproximal-Endothelial-Capillary_Aerocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

F2RL3 PCDH12 S1PR1 CLDN5 EDA2R

6.78e-05195975f1cbf82484f489fe7e0b5de6a49ea28d69f04e1a
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

F2RL3 AVPR2 PCDH12 S1PR1 CLDN5

6.78e-05195975f65053811074a7f2ff0368f3a63b88e2a08da1a0
ToppCellproximal-Endothelial-Capillary_Aerocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

F2RL3 PCDH12 S1PR1 CLDN5 EDA2R

6.78e-0519597513168c9632b58dd65ecb365df3832d95e7325919
ToppCell367C-Endothelial_cells-Endothelial-E|367C / Donor, Lineage, Cell class and subclass (all cells)

TSPAN18 F2RL3 PCDH12 S1PR1 CLDN5

6.78e-051959753b79e6bb525b17192ecec9e1227a29c419968144
Diseasehypertension (implicated_via_orthology)

AVPR2 S1PR1 ADRA2B GLP1R

7.62e-04128944DOID:10763 (implicated_via_orthology)
Diseasediastolic blood pressure, body mass index

CACNA1S GLP1R

1.17e-0316942EFO_0004340, EFO_0006336
DiseasePhenyllactate (PLA) measurement

SLC17A1 SLC38A7

1.66e-0319942EFO_0021662
Diseasejuvenile dermatomyositis

TGFBR1 ADRA2B

1.84e-0320942EFO_0000557
DiseaseICAM-1 measurement

S1PR2 S1PR5

2.65e-0324942EFO_0004520

Protein segments in the cluster

PeptideGeneStartEntry
ALRVVAGLAAAALVA

TMEM62

6

Q0P6H9
VLAFAVSLVALLAVT

TRHDE

41

Q9UKU6
ADLILSALERATVFL

C16orf89

36

Q6UX73
AAAALVLISIVAFTT

ALG5

16

Q9Y673
VEVIAILAASFGLLA

CASR

836

P41180
AAVQLLVTLSFLRSV

ERO1B

16

Q86YB8
TFVLAVNILDRFLAL

CCNG2

76

Q16589
VAVAAIALILGVAFL

CEND1

131

Q8N111
LAALFILTTAVLAER

C16orf54

41

Q6UWD8
LVSLAAADILVATLI

ADRA2B

51

P18089
FLSDSELVALLAARL

DNHD1

1361

Q96M86
VSRAVALLLAGLVAA

LVRN

11

Q6Q4G3
VAASVFTLVAIAVDR

NPFFR2

231

Q9Y5X5
AVILLLEAGALVARA

MC1R

96

Q01726
ILRSLVRLSVAAFAE

PCDH12

931

Q9NPG4
TALTVLERASLEFAL

CAPN15

816

O75808
AVDFHRLIASTAIVL

DUOX1

1126

Q9NRD9
SFILRALSVFIKDAA

GLP1R

186

P43220
LLRLLTAVSAAVAVA

HMCN2

6

Q8NDA2
AVALGLLVASSFVLL

KCNK7

171

Q9Y2U2
NLFLVSLALADLVVA

MTNR1B

76

P49286
VDRRTLLVFSFILAA

CPA5

16

Q8WXQ8
ASLALLAAFNVDVAR

ITGAE

11

P38570
ASAVAAIRTLLEFLK

EIF2B1

21

Q14232
LALAAVAAVALAVAL

PTGER1

156

P34995
AVSVLREIRALFALL

FRYL

706

O94915
VSRLVAAVVLLFAAC

KISS1R

261

Q969F8
AIAAAIALLALTALL

LRRC24

406

Q50LG9
ARLALLSAAALTLAA

KREMEN1

6

Q96MU8
LTALFLAAVSIERFL

GPR42

101

O15529
VAVTVRAALFRSSLA

PIGU

11

Q9H490
SFIVSLAAADLLLAL

DRD4

71

P21917
LVSLVAADFLLISNL

OXER1

131

Q8TDS5
AILFVDTADRLASLA

MED14

126

O60244
ALRLTAVVLASAVAF

F2RL3

281

Q96RI0
LDLAVVLFETATLRS

HSP90B1

711

P14625
VAFRDLSSAEAILAL

COMMD9

71

Q9P000
LTLIRSDAVALVDAF

ACOX1

596

Q15067
RLLAAAALAGLAVIS

IGLON5

11

A6NGN9
AAVAAQALVLLLIFL

GPR135

101

Q8IZ08
LALVSLFVAALATVG

C2CD2

16

Q9Y426
VTFNATLFALVRTAL

CACNA1S

1461

Q13698
LAARVALLSAALVRE

DUSP15

166

Q9H1R2
LTALFLAAVSIERFL

FFAR3

101

O14843
LRSLQAFVAVAARVF

IL23A

166

Q9NPF7
AAAASAISVARTLLV

SERPING1

456

P05155
ADAVASLLIVGAVFL

HCST

56

Q9UBK5
SLLVELLFSRAVAFN

ITGA7

21

Q13683
LLVGSLADTAVLFRA

ITGA7

501

Q13683
SLVALVVFGALTAAL

DLK2

306

Q6UY11
RVVTSLFIGAAILAV

DUOXA1

56

Q1HG43
VALSASVFSLLAIAI

S1PR1

126

P21453
LSASVFSLLAIAIER

S1PR2

116

O95136
FSLLAIAIERHVAIA

S1PR2

121

O95136
FVALTASVLSLLAIA

S1PR5

116

Q9H228
VLEAALATLLTVVAR

SAC3D1

171

A6NKF1
RLALVAAVLVLVASA

PRRT3

501

Q5FWE3
AITAIIVVFSLLAAL

CRB3

56

Q9BUF7
LVALTAATALVRLAQ

PKD1

3941

P98161
ENREIALFLILLATA

IZUMO3

171

Q5VZ72
RIALAISAIAVFLVL

TMEM179B

101

Q7Z7N9
VLLFEVLAVLDSAVT

SPATA22

261

Q8NHS9
DLAVAYLRSVLAVIA

TMEM150A

171

Q86TG1
LSDFFLTRNILSVIA

SLC17A1

321

Q14916
VLLSLLALIEAVVRF

RNF26

61

Q9BY78
ELLASAARLLASFVL

RNF26

211

Q9BY78
VAVARAFIILSVLTS

SLC38A7

321

Q9NVC3
IIAALFTASAVISLV

SCAMP1

266

O15126
AALSAIAAALLLAIL

TENM2

376

Q9NT68
LALLLVATAVAVATD

OCSTAMP

306

Q9BR26
ELIILIFAAIDLISS

OR8K3

196

Q8NH51
AIRTLSARAAAAFVL

RANBP6

196

O60518
SDFTRLSVLDLVVAL

RRP12

746

Q5JTH9
ALFVDLSVRSALVCL

SLC36A3

366

Q495N2
RLLLLVLAAAAAAAA

TGFBR1

11

P36897
RALTVSAVLLAFVAL

CLDN5

81

O00501
RALAAETFSAILTLE

CHRD

276

Q9H2X0
IALLAETALRFLELV

PIK3R4

486

Q99570
AVRARLALALALASV

SLIT3

11

O75094
LAERVVATESLVFLA

VPS50

726

Q96JG6
VILAFLAAVAAVLIS

VSTM5

151

A8MXK1
DSVRLALFTLAIVAI

TMPRSS11F

26

Q6ZWK6
IVISFLIAALASVLA

SLC7A1

66

P30825
LLSNVLFDVLRSVVF

RNF123

421

Q5XPI4
RLAVAEALTNLVFAL

PFAS

741

O15067
AAALARLLAAFLLLA

SPPL2B

6

Q8TCT7
VRLALFAAFLVTELL

PLPP5

16

Q8NEB5
VVAAVLLLVSAESAL

TNFRSF10B

41

O14763
ALFLTVVGSRVAALV

TMEM82

81

A0PJX8
VAALVVLEFSLRAVS

TMEM82

91

A0PJX8
RALAIAFAVGDLAAV

TMEM82

206

A0PJX8
ILIIFLAELSAAILA

TSPAN18

91

Q96SJ8
LAELSAAILAFIFRE

TSPAN18

96

Q96SJ8
RASQAILLLVSFVFT

VN1R5

266

Q7Z5H4
LVAAGRVLAVTLLAL

PIEZO1

196

Q92508
SDVLALVVALVAERF

SLC30A1

46

Q9Y6M5
ELSVLAALSLLVVFV

PIGG

696

Q5H8A4
AALLARAVVTGLLAL

TMEM147

196

Q9BVK8
EATLVALVSSLLVVF

EDA2R

136

Q9HAV5
LARAELALLSIVFVA

AVPR2

36

P30518
LALLSIVFVAVALSN

AVPR2

41

P30518
AALALLLAARVVAAF

TOR1B

11

O14657
ILLLFASVALVAAII

TNFRSF11A

216

Q9Y6Q6
LLILALTEALAFAIQ

TMEM108

16

Q6UXF1