Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

1.53e-0651083GO:0030156
GeneOntologyCellularComponentnuclear body

EPOR HDAC4 HIPK2 FANCL RAD54L2 CMYA5 TRIP12 BRD2 BRCA1 RBM27 FASTK ATF7IP CELF3 CHD5 TRIM8 ZFHX3 SDCBP2

6.19e-0690311217GO:0016604
GeneOntologyCellularComponentnuclear speck

EPOR HDAC4 RAD54L2 CMYA5 TRIP12 BRD2 RBM27 FASTK CHD5 SDCBP2

1.09e-0443111210GO:0016607
GeneOntologyCellularComponenttranscription regulator complex

HDAC4 ASCL5 HLF HIPK2 POU2AF1 GTF3C5 MLXIPL ATF7IP CHD5 ZFHX3 MED23

3.59e-0459611211GO:0005667
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3C RIMBP3B

4.45e-04281123GO:0002177
DomainFN3

EPOR MYLK SPEG CMYA5 RIMBP3 ATF7IP RIMBP3C IGSF9B RIMBP3B

2.15e-061991079PS50853
DomainFN3_dom

EPOR MYLK SPEG CMYA5 RIMBP3 ATF7IP RIMBP3C IGSF9B RIMBP3B

3.22e-062091079IPR003961
DomainFN3

EPOR MYLK SPEG CMYA5 RIMBP3C IGSF9B RIMBP3B

9.46e-051851077SM00060
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

SHROOM3 HDAC4 TEX14 RAD54L2 POM121C WNK1 TRIP12 CIC TMEM92 TULP4 CHD5 RNF38 IGSF9B SDCBP2 NEURL4 CRTC2

7.28e-134301121635044719
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA6C SHROOM3 CTC1 SPEG PER1 MED13L POM121C WNK1 CIC ZNF503 RADIL BRD2 TULP4 CHD5 TTLL4 CSPG4 DHX34 RBM38

1.61e-0811051121835748872
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SHROOM3 HDAC4 WNK1 NCKAP5L TRIP12 CIC MLXIPL RADIL NF1 ANKRD17 HELZ USP54 PPIP5K2 AKAP1 CRTC2

1.20e-078611121536931259
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

1.30e-074112319091768
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

3.24e-075112317855024
Pubmed

A human MAP kinase interactome.

HDAC4 HIPK2 SYNPO POM121C WNK1 NCKAP5L CIC CSN2 ATF7IP ANKRD17 HELZ

5.23e-074861121120936779
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SEMA6C SHROOM3 SYNPO RBM27 CHD5 TTLL4 ANKRD17 PPIP5K2 MED23 OGA DHX34

1.20e-065291121114621295
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PER1 TRAPPC8 POM121C WNK1 PARP4 RADIL TULP4 TXNDC16 POM121B NEURL4

4.66e-064931121015368895
Pubmed

Transcriptomic analysis of CIC and ATXN1L reveal a functional relationship exploited by cancer.

ATXN1L CIC

1.03e-052112230093628
Pubmed

Germline mutations in NF1 and BRCA1 in a family with neurofibromatosis type 1 and early-onset breast cancer.

NF1 BRCA1

1.03e-052112223624750
Pubmed

ATXN1L, CIC, and ETS Transcription Factors Modulate Sensitivity to MAPK Pathway Inhibition.

ATXN1L CIC

1.03e-052112228178529
Pubmed

The murine homolog of the human breast and ovarian cancer susceptibility gene Brca1 maps to mouse chromosome 11D.

NF1 BRCA1

1.03e-05211228566965
Pubmed

14-3-3 proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitylation and cytoplasmic body formation.

HDAC4 SPEG WNK1 CRTC2

1.04e-0542112423444366
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3C RIMBP3B

1.15e-0514112317662146
Pubmed

Human transcription factor protein interaction networks.

HIPK2 RAD54L2 POM121C ATXN1L CIC ZNF503 BRD2 BRCA1 RBM27 ATF7IP CHD5 ANKRD17 HELZ ZFHX3 USP54 RAI2

1.40e-0514291121635140242
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

SHROOM3 HDAC4 WNK1 NCKAP5L RADIL NF1 HELZ USP54 CRTC2

1.48e-05446112924255178
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

HDAC4 POM121C CIC ZNF503 PARP4 RBM27 ANKRD17 HELZ CRTC2

1.80e-05457112932344865
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

TRAPPC8 TRIP12 BRD2 CHD5 ZFHX3

2.16e-05103112532744500
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

RAD54L2 WNK1 ATXN1L SSPOP CIC RADIL BRCA1 CELF3 USP54 RAI2

2.84e-056081121016713569
Pubmed

POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation.

POM121C POM121B

3.08e-053112230802453
Pubmed

C5a-C5aR1 induces endoplasmic reticulum stress to accelerate vascular calcification via PERK-eIF2α-ATF4-CREB3L1 pathway.

OPRPN C5

3.08e-053112237603848
Pubmed

Attenuation of IgG immune complex-induced acute lung injury by silencing C5aR in lung epithelial cells.

OPRPN C5

3.08e-053112219620403
Pubmed

Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.

POM121C POM121B

3.08e-053112235507432
Pubmed

Effects of C5a and Receptor CD88 on Glutamate and N-Methyl-D-Aspartic Acid Receptor Expression in the Mouse Model of Optic Neuromyelitis.

OPRPN C5

3.08e-053112235509858
Pubmed

Complement C5a promotes antigen cross-presentation by Peyer's patch monocyte-derived dendritic cells and drives a protective CD8+ T cell response.

OPRPN C5

3.08e-053112233852847
Pubmed

Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis.

OPRPN C5

3.08e-053112234971753
Pubmed

TRIM25 promotes Capicua degradation independently of ERK in the absence of ATXN1L.

ATXN1L CIC

3.08e-053112233115448
Pubmed

Neurofibromatosis with male breast cancer--risk factor or co-incidence? Report of two rare cases.

NF1 BRCA1

3.08e-053112225267367
Pubmed

C5a receptor mediates neutrophil activation and ANCA-induced glomerulonephritis.

OPRPN C5

3.08e-053112219073822
Pubmed

C5a/C5aR pathway is essential for up-regulating SphK1 expression through p38-MAPK activation in acute liver failure.

OPRPN C5

3.08e-053112228028363
Pubmed

Complement factor C5a induces atherosclerotic plaque disruptions.

OPRPN C5

3.08e-053112225124749
Pubmed

Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes.

OPRPN C5

3.08e-053112219657368
Pubmed

Respiratory Syncytial Virus Exacerbates OVA-mediated asthma in mice through C5a-C5aR regulating CD4+T cells Immune Responses.

OPRPN C5

3.08e-053112229123203
Pubmed

C5a/CD88 signaling alters blood-brain barrier integrity in lupus through nuclear factor-κB.

OPRPN C5

3.08e-053112221929539
Pubmed

C5a-C5AR1 axis as a potential trigger of the rupture of intracranial aneurysms.

OPRPN C5

3.08e-053112238326494
Pubmed

Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis.

ATXN1L CIC

3.08e-053112220628574
Pubmed

Complement induction in spinal cord microglia results in anaphylatoxin C5a-mediated pain hypersensitivity.

OPRPN C5

3.08e-053112217687047
Pubmed

Signaling of the Complement Cleavage Product Anaphylatoxin C5a Through C5aR (CD88) Contributes to Pharmacological Hematopoietic Stem Cell Mobilization.

OPRPN C5

3.08e-053112228918528
Pubmed

Experimental Malaria in Pregnancy Induces Neurocognitive Injury in Uninfected Offspring via a C5a-C5a Receptor Dependent Pathway.

OPRPN C5

3.08e-053112226402732
Pubmed

Requisite role for complement C5 and the C5a receptor in granulomatous response to mycobacterial glycolipid trehalose 6,6'-dimycolate.

OPRPN C5

3.08e-053112216101818
Pubmed

C5a-C5aR1 Axis Activation Drives Envenomation Immunopathology by the Snake Naja annulifera.

OPRPN C5

3.08e-053112233936074
Pubmed

Dichotomous ovarian cancer-initiating potential of Pax8+ cells revealed by a mouse genetic mosaic model.

NF1 BRCA1

3.08e-053112237207276
Pubmed

C5aR activation in the absence of C5a: A new disease mechanism of autoimmune hemolytic anemia in mice.

OPRPN C5

3.08e-053112229277896
Pubmed

The C5a/C5aR1 Axis Contributes to the Pathogenesis of Acute Cystitis Through Enhancement of Adhesion and Colonization of Uropathogenic E. coli.

OPRPN C5

3.08e-053112235433513
Pubmed

Anaphylatoxin C5a creates a favorable microenvironment for lung cancer progression.

OPRPN C5

3.08e-053112223028051
Pubmed

C5 deficiency and C5a or C5aR blockade protects against cerebral malaria.

OPRPN C5

3.08e-053112218426986
Pubmed

WNK1 promotes renal tumor progression by activating TRPC6-NFAT pathway.

TRPC6 WNK1

3.08e-053112231022353
Pubmed

Complement C5a inhibition reduces atherosclerosis in ApoE-/- mice.

OPRPN C5

6.14e-054112221490292
Pubmed

C5L2 is required for C5a-triggered receptor internalization and ERK signaling.

OPRPN C5

6.14e-054112224631530
Pubmed

C5a/C5aR pathway accelerates renal ischemia-reperfusion injury by downregulating PGRN expression.

OPRPN C5

6.14e-054112229031143
Pubmed

RNA interferences targeting the Fanconi anemia/BRCA pathway upstream genes reverse cisplatin resistance in drug-resistant lung cancer cells.

FANCL BRCA1

6.14e-054112226385482
Pubmed

C5 inhibition prevents renal failure in a mouse model of lethal C3 glomerulopathy.

OPRPN C5

6.14e-054112228139294
Pubmed

Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes.

POM121C POM121B

6.14e-054112217900573
Pubmed

The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues.

BRCA1 CSN2

6.14e-05411227550308
Pubmed

Genetic mapping of opioid binding protein gene(s) to mouse chromosome 9.

EPOR ICAM1

6.14e-05411228439730
Pubmed

Functional roles for C5a receptors in sepsis.

OPRPN C5

6.14e-054112218454156
Pubmed

Complement dependency of cardiomyocyte release of mediators during sepsis.

OPRPN C5

6.14e-054112221478262
Pubmed

The C5a/C5aR2 axis promotes renal inflammation and tissue damage.

OPRPN C5

6.14e-054112232191644
Pubmed

Intracellular complement (complosome) is expressed in hematopoietic stem/progenitor cells (HSPCs) and regulates cell trafficking, metabolism and proliferation in an intracrine Nlrp3 inflammasome-dependent manner.

OPRPN C5

6.14e-054112237055506
Pubmed

Complement 5a Enhances Hepatic Metastases of Colon Cancer via Monocyte Chemoattractant Protein-1-mediated Inflammatory Cell Infiltration.

OPRPN C5

6.14e-054112225739439
Pubmed

Complement C5a Receptor 1 Exacerbates the Pathophysiology of N. meningitidis Sepsis and Is a Potential Target for Disease Treatment.

OPRPN C5

6.14e-054112229362231
Pubmed

A new role of the complement system: C3 provides protection in a mouse model of lung infection with intracellular Chlamydia psittaci.

OPRPN C5

6.14e-054112223189195
Pubmed

O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver.

MLXIPL OGA

6.14e-054112221471514
Pubmed

Tumor necrosis factor-alpha enhances neutrophil adhesiveness: induction of vascular cell adhesion molecule-1 via activation of Akt and CaM kinase II and modifications of histone acetyltransferase and histone deacetylase 4 in human tracheal smooth muscle cells.

HDAC4 ICAM1

6.14e-054112218227124
Pubmed

Airway hyper-reactivity mediated by B-1 cell immunoglobulin M antibody generating complement C5a at 1 day post-immunization in a murine hapten model of non-atopic asthma.

OPRPN C5

6.14e-054112215379984
Pubmed

C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice.

OPRPN C5

6.14e-054112223420882
Pubmed

Expressions of C5a and its receptor CD88 after spinal cord injury in C3-deficient mice.

OPRPN C5

6.14e-054112223033813
Pubmed

Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock.

OPRPN C5

6.14e-054112233495506
Pubmed

Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis.

OPRPN C5

6.14e-054112235649359
Pubmed

NG2-cells are not the cell of origin for murine neurofibromatosis-1 (Nf1) optic glioma.

NF1 CSPG4

6.14e-054112223318450
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

PER1 POM121C NCKAP5L BRD2 BRCA1 CHD5 ANKRD17 HELZ ZFHX3 SIGLEC1 USP54 DHX34 CDH16

6.43e-0511161121331753913
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

SGSH ICAM1 GATB SYNPO ACVR2B CUBN WDR3 NF1 BRD2 N6AMT1 CSPG4 SLC49A4 HELZ SDCBP2

7.23e-0512931121415342556
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

POM121C TRIP12 WDR3 NF1 RBM27 ANKRD17 USP54 MED23

9.30e-05440112834244565
Pubmed

Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis.

ATXN1L CIC

1.02e-045112232878998
Pubmed

C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a.

OPRPN C5

1.02e-045112217322907
Pubmed

Molecular pathogenesis of Philadelphia chromosome negative myeloproliferative disorders.

EPOR THPO

1.02e-045112215572213
Pubmed

Drusen complement components C3a and C5a promote choroidal neovascularization.

OPRPN C5

1.02e-045112216452172
Pubmed

A novel role of complement in retinal degeneration.

OPRPN C5

1.02e-045112223074214
Pubmed

Complement-induced activation of MAPKs and Akt during sepsis: role in cardiac dysfunction.

OPRPN C5

1.02e-045112228572445
Pubmed

Complement activation triggers metalloproteinases release inducing cervical remodeling and preterm birth in mice.

OPRPN C5

1.02e-045112221801872
Pubmed

Maea expressed by macrophages, but not erythroblasts, maintains postnatal murine bone marrow erythroblastic islands.

EPOR SIGLEC1

1.02e-045112230674470
Pubmed

53BP1-shieldin-dependent DSB processing in BRCA1-deficient cells requires CST-Polα-primase fill-in synthesis.

CTC1 BRCA1

1.02e-045112235027730
Pubmed

ATF-2 controls transcription of Maspin and GADD45 alpha genes independently from p53 to suppress mammary tumors.

NF1 BRCA1

1.02e-045112217700520
Pubmed

Disruption of the C5a receptor gene increases resistance to acute Gram-negative bacteremia and endotoxic shock: opposing roles of C3a and C5a.

OPRPN C5

1.02e-045112218063050
Pubmed

TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes.

TRIP12 BRCA1

1.02e-045112222884692
Pubmed

ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.

ATXN1L CIC

1.02e-045112229526553
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

CTC1 FANCL RAD54L2 MED13L GTF3C5 BRCA1 RECQL4 RHNO1

1.14e-04453112829656893
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

SPEG TULP4 RBM27 CHD5 TXNDC16

1.42e-04153112510718198
Pubmed

Distinct roles of the anaphylatoxin receptors C3aR, C5aR1 and C5aR2 in experimental meningococcal infections.

OPRPN C5

1.53e-046112231274379
Pubmed

Cytokinesis failure in RhoA-deficient mouse erythroblasts involves actomyosin and midbody dysregulation and triggers p53 activation.

EPOR MYLK

1.53e-046112226228485
Pubmed

Complement inhibition and statins prevent fetal brain cortical abnormalities in a mouse model of preterm birth.

OPRPN C5

1.53e-046112224184716
Pubmed

High-grade serous carcinomas arise in the mouse oviduct via defects linked to the human disease.

NF1 BRCA1

1.53e-046112228608929
Pubmed

Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma.

HDAC4 BRD2

1.53e-046112224229708
Pubmed

IVIG immunotherapy protects against synaptic dysfunction in Alzheimer's disease through complement anaphylatoxin C5a-mediated AMPA-CREB-C/EBP signaling pathway.

OPRPN C5

1.53e-046112223911420
Pubmed

Complement is a central mediator of radiotherapy-induced tumor-specific immunity and clinical response.

OPRPN C5

1.53e-046112225888260
Pubmed

Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis.

OPRPN C5

1.53e-046112218567839
Pubmed

C5a regulates NKT and NK cell functions in sepsis.

OPRPN C5

1.53e-046112222058413
Pubmed

A Combined PD-1/C5a Blockade Synergistically Protects against Lung Cancer Growth and Metastasis.

OPRPN C5

1.53e-046112228288993
Pubmed

Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial Metabolic Agility.

OPRPN C5

1.53e-046112231624141
Pubmed

Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment.

ICAM1 SYNPO CDH16

1.65e-0433112336522157
InteractionTOP3B interactions

SEMA6C SHROOM3 HDAC4 CTC1 SPEG PER1 MED13L POM121C WNK1 CIC ZNF503 RADIL BRD2 TULP4 FASTK CHD5 TTLL4 CSPG4 ANKRD17 HELZ OGA DHX34 ADAMTSL4 RBM38

8.42e-07147010924int:TOP3B
InteractionF12 interactions

PER1 POM121C NF1 RPUSD3 RECQL4 HELZ

3.78e-06771096int:F12
InteractionCTBP1 interactions

HDAC4 HIPK2 FANCL NCKAP5L ATXN1L CIC BRCA1 RECQL4 HELZ MED23 RAI2

1.27e-0540610911int:CTBP1
InteractionERG interactions

HIPK2 RAD54L2 ATXN1L TRIP12 CIC BRD2 ATF7IP TRIM8

2.89e-052231098int:ERG
InteractionTBR1 interactions

ATXN1L CIC ZNF503 BRD2 RECQL4 ZFHX3

3.44e-051131096int:TBR1
InteractionB4GALT2 interactions

PER1 POM121C NACC2 RECQL4 DCHS1 HELZ

4.61e-051191096int:B4GALT2
Cytoband10q22.2

SAMD8 ZNF503 USP54

1.41e-0441112310q22.2
Cytoband22q11.21

RIMBP3 RIMBP3C RIMBP3B CCDC188

1.64e-04111112422q11.21
Cytoband17q22

HLF TEX14 AKAP1

1.74e-0444112317q22
Cytoband19p13.3-p13.2

EPOR ICAM1

5.27e-0414112219p13.3-p13.2
CytobandEnsembl 112 genes in cytogenetic band chr17q22

HLF TEX14 AKAP1

1.33e-03881123chr17q22
GeneFamilyFibronectin type III domain containing

EPOR MYLK CMYA5 ATF7IP IGSF9B

3.39e-04160685555
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

HDAC4 SAMD8 HIPK2 FAM168A TRIM8 USP54 OGA

3.31e-071771127e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 TEX14 C5 USP54 AKAP1

3.57e-071791127fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN9 NPBWR1 MYLK SPEG SYNPO CSPG4 ZFHX3

4.98e-071881127d1a4cd4db95d8d32b79156290f7867f32824cc87
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 UNC13D NLGN1 C5 USP54

9.65e-0713011266434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

BNC2 ICAM1 ACVR2B TTLL4 SLC49A4 MED23

5.77e-06177112652c2ba74a8605260a2623e7d151286e504ac4d19
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54 AKAP1

6.35e-061801126b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54 AKAP1

6.77e-06182112617ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54 AKAP1

6.98e-061831126e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54 AKAP1

7.20e-061841126d0c212a8fbaad24597a84018442b25c61c17ea58
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54 AKAP1

7.20e-061841126ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54 AKAP1

7.66e-061861126e83718fabb057100835d3357df407f283d23fe16
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 UNC13D NLGN1 C5 USP54

7.90e-06187112658d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54 AKAP1

8.14e-0618811264bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCelldroplet-Kidney-nan-21m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SPEG TRPC6 SYNPO RIMBP3 CSPG4

8.65e-061901126e04f47705851563515b6a66a2634cf7a574f7bda
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SPEG TRPC6 SYNPO CSPG4 ZFHX3

9.18e-0619211263617d2bc7e33d981f3ec349e9962d8d4bd822fbd
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 SHROOM3 NLGN1 CUBN MED13L ANKRD17

9.18e-061921126e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SPEG TRPC6 SYNPO CSPG4 ZFHX3

9.74e-06194112680be44e9ddd9f6ddd9dff7cba0eb457431204c2d
ToppCell11.5-Distal-Mesenchymal-Airway_Smooth_Muscle|Distal / Age, Tissue, Lineage and Cell class

MYLK SPEG HIPK2 ZFHX3 RAI2 RBM38

1.03e-05196112605530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCellSkin-Mesangial|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

MYLK SPEG SYNPO SSPOP TTLL4 ALG10

1.13e-051991126bcb78838a91cc7828680fb413fbacdb091c5fac0
ToppCell11.5-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

MYLK SPEG HIPK2 ZFHX3 RAI2 RBM38

1.13e-0519911261a8c77d241bd817a195e1532fd25f51358cb1ff1
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SPEG ACVR2B CSPG4 TRIM8 DCHS1

3.64e-051481125065177aaa63c0441d312260b43ecdac78c84ad03
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

4.26e-051531125e7a074ea8232bacf924be78a244a8507c7e1ebc8
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CTC1 SPEG TRPC6 GATB RADIL

4.82e-051571125f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MYLK SPEG TRPC6 CSPG4 RAI2

5.12e-0515911257cda111bb98f1241989e49d490bdf51a712ea589
ToppCell3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ONECUT2 UGT3A1 SSPOP MLXIPL RBM27

6.65e-0516811254e2e4c88ada772e9ba6e72c9ae3a05c063e93318
ToppCell3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ONECUT2 UGT3A1 SSPOP MLXIPL RBM27

6.65e-051681125ee4dab089adef2f47a9d39d91934523331a8b81c
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR TRPC6 B4GALNT2 AKAP1 ADAMTSL4

6.83e-0516911252d23b4cee060f8adddc430c1c10d4e25205b4af6
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR TRPC6 B4GALNT2 AKAP1 ADAMTSL4

6.83e-051691125ecaf08e8e0b54d1c97a02bc1f65409fd43d68227
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR TRPC6 B4GALNT2 AKAP1 ADAMTSL4

6.83e-051691125ad6af6609acf158cb79e45ee7ca9af332be3c40c
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR SPEG TRPC6 CSPG4 TPBG

7.63e-0517311253059325901b1e5e12a1a91183f14267288b2f600
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYLK SPEG NLGN1 ZFHX3 IGSF9B

7.63e-051731125cb6389536195443633adb06e5f1b7483530773d1
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR SPEG TRPC6 CSPG4 TPBG

7.63e-05173112536c8338463ee4cc432f568728d55989360f9a68d
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

7.84e-051741125d0e3d15731de6c19c232e3aa492c39d8151cf4ed
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPOR TRPC6 SSPOP CSPG4 TPBG

8.06e-0517511252a53d4f140d5ab096efe8118d8aa351db7838b49
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPOR TRPC6 SSPOP CSPG4 TPBG

8.06e-051751125fb91a45763e4c48d993094a13088ffc19f1e2574
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BNC2 MYLK HLF ACVR2B ZNF503

8.73e-0517811250fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

MYLK SPEG HIPK2 CSPG4 ZFHX3

8.96e-051791125a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SPEG TRPC6 CSPG4 IGSF9B

9.20e-051801125a37cc885fe3f6cb9df69d43358064c83c18412e7
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SPEG TRPC6 CSPG4 IGSF9B

9.20e-05180112563a6d532b16b8b15c7c9102148d7297ee3afd641
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

BNC2 UGT3A1 NLGN1 CUBN MLXIPL

9.20e-051801125864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

MYLK SPEG NLGN1 ZFHX3 IGSF9B

9.20e-051801125d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

9.44e-0518111250513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGSH UNC13D SDCBP2 DHX34 NEURL4

9.44e-0518111258a8061725e718c89a4c751a415120c5312acc757
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR SHROOM3 TRPC6 CSPG4 TPBG

9.69e-0518211259edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 C5 USP54 AKAP1

9.69e-0518211251e2149b222a3e9f64841aed45288a6f29394e7b0
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 C5 USP54 AKAP1

9.69e-051821125d1a1feef318062f25493355d7beee8e5fb0e4206
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA3 UGT3A1 HLF CUBN CDH16

9.69e-051821125faf0dfa3adc2d2706b6942b5127093ccdc856447
ToppCellControl-Epithelial_alveolar-AT_2-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

9.69e-051821125e97681a4102f3095d5d9e90ad70f1dc46e90983a
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR SHROOM3 TRPC6 CSPG4 TPBG

9.69e-051821125aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA3 UGT3A1 HLF CUBN CDH16

9.69e-051821125be8dd52898525ce6632af0adc2801944f3ac10bd
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 C5 USP54 AKAP1

9.94e-0518311255f2db95d44b7de68779de098892892af540fd431
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

9.94e-05183112506ac66726ec53db810ebb90ec69cfdb903da53f6
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 UNC13D NLGN1 C5

9.94e-051831125ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SGSH ICAM1 HLF ACVR2B TRIM8

9.94e-0518311253cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

CAPN9 MYLK SYNPO USP54 RAI2

9.94e-0518311256821dca076318115d360ff426eb1218cfe104063
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 UNC13D NLGN1 USP54

1.02e-04184112542ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellControl-Epithelial_alveolar-AT_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

1.02e-04184112551e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

1.02e-0418411257cc5796557379c3d1db078c1aeda40659c6e401c
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPOR SHROOM3 TRPC6 CSPG4 TPBG

1.02e-0418411254cb5f299dd7413e0be1ad7af817ee614b23a18ae
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPOR SHROOM3 TRPC6 CSPG4 TPBG

1.02e-04184112539bb0eb55bdc2cea46e41c7f21d8c5883f14e6bd
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

1.05e-0418511253bef59cc0aa939d2a7e52f0f6c61bc00528fe50b
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1-AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

1.05e-04185112568f428e169cfb77de970bdfdeea9b9f16f68d2ba
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

1.05e-0418511250d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 C5 USP54 AKAP1

1.05e-041851125fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCellControl-Epithelial_alveolar|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 UNC13D NLGN1 C5 USP54

1.05e-0418511253937e026add96a396122139daf8011cfbc60e75c
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Mega-Mast|bone_marrow / Manually curated celltypes from each tissue

SEMA6C TRPC6 RADIL RECQL4 CCDC188

1.05e-041851125a62ebaff92f2ed27b27b32c27c89cfbe2cb35116
ToppCellLPS_only-Epithelial_alveolar|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

1.07e-041861125e0a2ea4b46af742bc7c9b2072bb85e27d5c92712
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

1.07e-0418611254e94158db52df41d71e67b02b9895a358eebee0f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SHROOM3 ICAM1 UNC13D MLXIPL USP54

1.10e-0418711254ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

1.10e-041871125201ff693e4756ee3e44762885b3a303a77eb535b
ToppCellLPS_only-Epithelial_alveolar-AT_1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

1.10e-041871125ff26a533d310126521efe1d05cf8b9d32e524550
ToppCellLPS-IL1RA-Epithelial_alveolar|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

1.13e-0418811256164d467b612767ceba15de34176bcc8e8c36ab8
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

1.13e-04188112543a0508d2524a5b310e89e9422843dcaab999bc3
ToppCellCOPD-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

SPEG HIPK2 SYNPO CSPG4 IGSF9B

1.13e-0418811259ffef4b01d0ddd6913c9ed6be79aeaaabd5e41ed
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BNC2 SYNPO NCKAP5L DCHS1 ADAMTSL4

1.16e-041891125bccb3481ffed597c845fe860da658505316105b5
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 ABCA3 NLGN1 C5 USP54

1.16e-0418911255f883ef4cc0383142d538ae61f4fb40dfdb8ef18
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 MYLK SPEG TRPC6 ZFHX3

1.16e-0418911257ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

BNC2 SPEG NLGN1 CMYA5 TPBG

1.16e-04189112587189275234b5d59484c58acbb14a09903f2b578
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BNC2 SPEG HLF NLGN1 CMYA5

1.16e-0418911254dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BNC2 SPEG HLF NLGN1 CMYA5

1.16e-0418911250d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

CAPN9 SHROOM3 ICAM1 UNC13D RADIL

1.16e-0418911255a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SPEG TRPC6 SYNPO ZFHX3

1.19e-0419011251803b1e7c36285f9eaabc3c6e9a9752c5908db3d
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

ONECUT2 ZNF503 CHD5 TXNDC16 ZFHX3

1.19e-0419011256e92c78799f34b31d098854503c796edb0dc7f80
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEG TRPC6 CSPG4 ZFHX3 IGSF9B

1.19e-04190112573d94fbae92029745989a8712eed8b99fd84c193
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SPEG TRPC6 CSPG4 ZFHX3

1.22e-0419111258597a8af294f24496c317d995f07eb5dcc25c13c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

SAMD8 PER1 MED23 OGA RBM38

1.22e-0419111251ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK SPEG THPO CHD5 CSPG4

1.22e-041911125d35692c652977500a3c36aa26c347a072b71e441
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK SPEG THPO CHD5 CSPG4

1.22e-0419111252a107e9096eb58b81b3da61547904d85754f6b2f
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK ICAM1 SYNPO NCKAP5L BRD2

1.22e-0419111252f733d510a4862565a817f59829d8387d7ea26d9
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK ICAM1 SYNPO NCKAP5L BRD2

1.22e-0419111258691eba35793e4e90f93d50c2145847ee51289f7
ToppCelldroplet-Heart-HEART-1m-Hematologic-red_blood_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA3 GATB BRCA1 RBM38

1.23e-0410111246c4524be89cf3eb06769c2963dcded3da1e71ca0
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SPEG CSPG4 ZFHX3 RBM38

1.25e-04192112543228bddca2f606ddcae9731f04c6b1502c4b85a
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SPEG CSPG4 ZFHX3 RBM38

1.25e-041921125f5463c6bcc5c69ac562bec028f7a105c471f2fbe
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYLK SPEG TRPC6 HLF CSPG4

1.25e-0419211252cc712186e37fb21a964c032765c36a8b4a852cf
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SPEG CSPG4 ZFHX3 RBM38

1.25e-04192112520fd69eb60b93d22d9be39de44b733db6d761dde
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 NLGN1 CUBN CMYA5 MLXIPL

1.28e-04193112582e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellcellseq2-Epithelial-Epithelial_Alveolar-AT2-AT2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA3 HLF RAD54L2 TTLL4 TRIM8

1.31e-041941125df835578d86a49ae5af5632152fbab9548c0a448
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM3 ZPLD1 UGT3A1 CMYA5 CDH16

1.31e-0419411254579b4a44f7c731553a284843c296866027d7c0e
ToppCellcellseq2-Epithelial-Epithelial_Alveolar|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA3 HLF RAD54L2 TTLL4 TRIM8

1.31e-0419411250715f2d55f4a6d2edda1b3dc52f12d25ce59eb10
ToppCellcellseq2-Epithelial-Epithelial_Alveolar-AT2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA3 HLF RAD54L2 TTLL4 TRIM8

1.31e-041941125a4f7cd507eba40985d82635bbae28c7f5703f883
DrugKynurenine, 3-hydroxy (R,S) [2147-61-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A

CTC1 ICAM1 HIPK2 WNK1 FASTK HELZ OGA DHX34

4.09e-0619410885641_DN
Drugaspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A

EPOR ICAM1 PER1 HIPK2 GTF3C5 NF1 HELZ OGA

4.58e-0619710885201_DN
DiseaseMalignant neoplasm of breast

EPOR NPBWR1 ABCA3 CATSPERE HDAC4 PER1 CUBN TRAPPC8 WNK1 PKDREJ CIC NF1 BRCA1 CHD5 USP54

8.76e-06107410815C0006142
Diseasepulmonary hypertension (is_marker_for)

HDAC4 ICAM1 TRPC6 THPO

9.11e-05641084DOID:6432 (is_marker_for)
DiseaseAcute monocytic leukemia

CTC1 FANCL BRCA1

1.17e-04261083C0023465
Diseasebitter alcoholic beverage consumption measurement

CIC MLXIPL NF1 ZFHX3 IGSF9B

1.33e-041331085EFO_0010092
DiseaseMiller Dieker syndrome

CTC1 FANCL BRCA1

1.63e-04291083C0265219
Diseasenonsyndromic deafness (implicated_via_orthology)

ALG10 PPIP5K2

1.97e-0461082DOID:0050563 (implicated_via_orthology)
DiseaseFocal Segmental Glomerulosclerosis, Not Otherwise Specified

TRPC6 SYNPO

4.70e-0491082C4049702
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 40

BRCA1 DHX34

4.70e-0491082C4225275
Diseaseproteinuria (biomarker_via_orthology)

ICAM1 TRPC6

5.86e-04101082DOID:576 (biomarker_via_orthology)
DiseaseGastric Adenocarcinoma

SPEG TEX14 BRD2

6.05e-04451083C0278701
Diseaselevel of Diacylglycerol (18:1_18:1) in blood serum

MLXIPL B4GALNT2

7.14e-04111082OBA_2045170
Diseaseretinopathy of prematurity (biomarker_via_orthology)

EPOR ICAM1

8.55e-04121082DOID:13025 (biomarker_via_orthology)
DiseaseColorectal Carcinoma

ABCA3 PER1 CUBN WNK1 NF1 CHD5 DCHS1 B4GALNT2 SDCBP2

1.12e-037021089C0009402
DiseaseIntellectual Disability

HDAC4 MED13L CIC NF1 BRCA1 TRIM8 MED23

1.31e-034471087C3714756
DiseaseSitus ambiguus

SHROOM3 ACVR2B

1.35e-03151082C0266642
Diseasebrain edema (biomarker_via_orthology)

ICAM1 C5

1.35e-03151082DOID:4724 (biomarker_via_orthology)
Diseasemonocyte percentage of leukocytes

SEMA6C MED13L WNK1 MLXIPL NF1 BRCA1 RBM27 B4GALNT2 NEURL4

1.48e-037311089EFO_0007989
DiseaseProfound Mental Retardation

HDAC4 MED13L CIC NF1

1.73e-031391084C0020796
DiseaseMental Retardation, Psychosocial

HDAC4 MED13L CIC NF1

1.73e-031391084C0025363
DiseaseMental deficiency

HDAC4 MED13L CIC NF1

1.73e-031391084C0917816
DiseaseMYELODYSPLASTIC SYNDROME

CTC1 FANCL BRCA1

1.93e-03671083C3463824
Diseasevisceral adipose tissue measurement

BNC2 NLGN1 POM121C WNK1 TRIP12 HELZ SIGLEC1

1.99e-034811087EFO_0004765
Diseasefreckles

BNC2 AKAP1

2.42e-03201082EFO_0003963
DiseaseSarcoma

CIC NF1

2.66e-03211082C1261473
Diseaseunipolar depression, bipolar disorder, schizophrenia, sex interaction measurement

C6orf89 ZPLD1 SDCBP2

2.76e-03761083EFO_0003761, EFO_0008343, MONDO_0004985, MONDO_0005090
DiseaseAcute Lung Injury

MYLK ICAM1

2.92e-03221082C0242488
Diseasereaction time measurement

BNC2 C6orf89 HLF GATB MED13L MLXIPL TXNDC16 ZFHX3

2.93e-036581088EFO_0008393
Diseaselung non-small cell carcinoma (is_marker_for)

ICAM1 NF1 BRCA1 ZFHX3

3.51e-031691084DOID:3908 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
TNIYAPPLPSLALPS

AKAP1

681

Q92667
YSLVAPAFPQPPALV

CELF3

336

Q5SZQ8
LPPAEPLGNVPFLLY

ASCL5

106

Q7RTU5
QYVISSPPPILENPT

ADAMTSL4

596

Q6UY14
TFPLLTIPEIPGYLP

CATSPERE

216

Q5SY80
LTISPGPVTPIPVLY

CTC1

191

Q2NKJ3
APPLLRVSGPYFPTL

CSPG4

1376

Q6UVK1
PYLFPVAAVEAPVLP

CHD5

996

Q8TDI0
PLLVQPNLPFGYPVH

B4GALNT2

186

Q8NHY0
QYINPVSAPLLGLPP

BNC2

326

Q6ZN30
VQPVPPFYRSLLTPG

BNC2

566

Q6ZN30
PYPPFIADPFLVAIQ

ABCA3

246

Q99758
PNLPPLVLYDATSLP

GATB

341

O75879
PGILPSYSLPFSQPL

RAD54L2

1376

Q9Y4B4
LPLAYPPPQFAHALL

ANKRD17

1881

O75179
PPATLLVPYPVIVPL

RAI2

226

Q9Y5P3
RLPPPLPQNLLYTVS

RBM27

411

Q9P2N5
YPPAIVQPSVVIPAA

RBM38

146

Q9H0Z9
VIPAAPVPSLSSPYI

RBM38

156

Q9H0Z9
VTFDTLLAGPPYPPL

RIMBP3B

1076

A6NNM3
VTFDTLLAGPPYPPL

RIMBP3C

1076

A6NJZ7
VLESYENPPPIVLPS

RADIL

766

Q96JH8
AVLPVRTQDPFLPYP

FASTK

441

Q14296
VPGTPTPPIFEQLQY

DCHS1

781

Q96JQ0
YLLPVAPSKPTAPIF

MYLK

611

Q15746
LPVPNPSLPYEQTIV

HIPK2

71

Q9H2X6
APLPLYTSPSLPNIT

HDAC4

341

P56524
SPIQLYSPPFILAPI

MED13L

1791

Q71F56
VQPNSIPSAIYPAPV

FAM168A

171

Q92567
PSPLQVPTYPQLTLE

NCKAP5L

576

Q9HCH0
VPTYPQLTLEVPQAP

NCKAP5L

581

Q9HCH0
LPYAVPPNFLPSPLL

ATXN1L

146

P0C7T5
LVLPNYLFPTPSSYP

PER1

921

O15534
LYLLPPGAPFIELLP

GHDC

311

Q8N2G8
VDPPVQIQSPYLPIY

MED23

941

Q9ULK4
NTYTTLTPLQPLPPI

ONECUT2

146

O95948
NPTFIPPPYGVLRSL

HLF

11

Q16534
PVIQFLGVPYAAPPT

NLGN1

76

Q8N2Q7
FPILAPAVGSYLPPT

PARP4

1316

Q9UKK3
PLAIQLPPVLIIGPY

HELZ

656

P42694
LTLPPPPQLGYSITA

POM121C

496

A8CG34
EQLTLPPPPQLGYSI

POM121B

101

A6NF01
LPTSTLQYQPPAPAL

POU2AF1

186

Q16633
NPYRIPPLFPIKSFV

BRCA1

976

P38398
PSKPTLPLVIPYSQV

CUBN

2651

O60494
LPSPLPQEFTYLNSP

FCRL1

346

Q96LA6
QRLPPYPYSSPSLVL

CRTC2

481

Q53ET0
LIFSATLAYFPPRPP

SLC49A4

241

Q96SL1
YVVNPTPFEGLVPPL

CCDC188

361

H7C350
LVATPLFLKPGIPYP

C5

356

P01031
ETPPYLLSPVKPQTL

CMYA5

2806

Q8N3K9
PIPYGFLPQNILPLA

CSN2

71

P05814
QVVYTTLPAPPAQAP

ATF7IP

1061

Q6VMQ6
NSLIPAAEPLPPSYV

EPOR

491

P19235
PYQLQTFVLPATPPQ

ICAM1

206

P05362
YFVIQPFSPLAPEPV

C6orf89

76

Q6UWU4
LPPGEYILIPSTFEP

CAPN9

461

O14815
IEPPPPASLETAILY

DHX34

546

Q14147
EQPPPVLLSPSLQYA

NEURL4

1471

Q96JN8
PAPALTLAPVPSQYL

CDH16

661

O75309
PLPAPLAVAVPVVYA

NPBWR1

31

P48145
VIALTYTVLPPFLNP

OR14I1

271

A6ND48
DTPVELLAPLPPYFS

RPUSD3

326

Q6P087
QSLPYVFIPPDIQTP

RHNO1

146

Q9BSD3
LPVPYAAFPPLISSD

RNF38

256

Q9H0F5
PPSLNYIPPVLQLSG

TEX14

796

Q8IWB6
PSPQIRFPLATYILP

SSPOP

2046

A2VEC9
QTYPPLPDIFLDSVP

SAMD8

181

Q96LT4
LYALPPPPQFYSSLI

FANCL

101

Q9NW38
LFFQPPPLTPTSKVY

OGA

701

O60502
VTFDTLLAGPPYPPL

RIMBP3

1076

Q9UFD9
PEVPSLDPTVLPLYS

RECQL4

441

O94761
QPPYQLRPSLFVLSP

SYNPO

806

Q8N3V7
LYLGPQSTVPPSFLP

PKDREJ

621

Q9NTG1
AQPGQPLLPTSIYPV

SHROOM3

456

Q8TF72
PIPFFLAIYLPISNP

OPRPN

126

Q99935
APTPFPIELLPLGYS

MLXIPL

466

Q9NP71
DPLDVLVPYFVPNTP

SGSH

216

P51688
AISPPPVLYPNLAEL

SDCBP2

36

Q9H190
LYTPPPEIPTTVLNI

BRD2

226

P25440
PYVIYRLNIPLPPTS

ALG10

421

Q5BKT4
YEPPPTAPTLLTVLA

ACVR2B

126

Q13705
APLAQPSQAPPSLVY

CIC

1106

Q96RK0
VSLSAPPPPYSEVIL

TMEM92

111

Q6UXU6
QEPAVVLQPLYPPSL

TULP4

1221

Q9NRJ4
GLPSPLSYVPVFPSL

UGT3A1

176

Q6NUS8
YFDPLPPLPLLVLVN

TXNDC16

681

Q9P2K2
TPDPPTIISYLPGLL

ZPLD1

136

Q8TCW7
PPQALQTLALPLTPY

SPEG

2231

Q15772
IFIAPGNLSLPIPIY

ERVFRD-1

326

P60508
PPTSLQVPAAYPGIL

IGSF9B

1081

Q9UPX0
LTPTSPYPPALQSQL

NF1

2756

P21359
TPQLYTTFLPPPEGV

SEMA6C

676

Q9H3T2
PSSPAVLTVLYPPRQ

SIGLEC1

586

Q9BZZ2
EYLQPLPSTPVSPIE

ZNF503

91

Q96F45
PLPQLPLPYINSSAT

TRAPPC8

661

Q9Y2L5
PILPPSLQTSYVFLG

TPBG

346

Q13641
LYIPPPIFSRLDAPV

GTF3C5

166

Q9Y5Q8
LFTTSPLLLQYIPRP

TRIM49B

391

A6NDI0
PVPFNLVPSPKSLFY

TRPC6

761

Q9Y210
LNTYTPAKILPTPPA

PPIP5K2

1181

O43314
LPTPLLPQYPVSQIP

WNK1

831

Q9H4A3
LYSLNPSLPTPQPVR

WDR3

391

Q9UNX4
PFSTPVPFLQSVPLY

TRIM8

351

Q9BZR9
VSNPLEVYLIPTPPE

TRIP12

1446

Q14669
VRPALIYSLFPNVPP

TTLL4

571

Q14679
PLLYPPFPQVPVVLQ

PRRT1B

116

A0A1B0GWB2
EVPQTRLPLTYPAPN

UNC13D

1036

Q70J99
NPPVLAPTSTAFPYL

VPS37A

126

Q8NEZ2
LPPILAPQAYLNFAP

nan

61

Q6ZTC4
APQAYLNFAPPTLVP

nan

66

Q6ZTC4
LPTAYPALQGIPPVL

ZFHX3

3111

Q15911
PQLYLPQPQFLSPDV

USP54

1471

Q70EL1
TGQYTLFPLPPTLPT

THPO

301

P40225
PLTPYLPAVPSSFRV

NAALADL1

256

Q9UQQ1
AAPYVVSPSVPIPLL

NACC2

156

Q96BF6
VDLLVFNPPYVVTPP

N6AMT1

116

Q9Y5N5