Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	hippocampal mossy fiber	MICAL1 MAP1B	2.57e-04	7	74	2	GO:0097457
GeneOntologyCellularComponent	nuclear protein-containing complex	PPARGC1B GTF2E1 ERCC6 ARID4B CEBPZ RBBP5 CWC15 CLNS1A PES1 SSRP1 DEK SF3B2 TFDP2 HELB	2.96e-04	1377	74	14	GO:0140513
GeneOntologyCellularComponent	B-WICH complex	ERCC6 DEK	3.41e-04	8	74	2	GO:0110016
Domain	-	LSG1 GNL2	5.15e-05	3	78	2	1.10.1580.10
Domain	GTP-bd_ortho_bundle	LSG1 GNL2	1.03e-04	4	78	2	IPR023179
Domain	G_CP_dom	LSG1 GNL2	3.57e-04	7	78	2	IPR030378
Domain	G_CP	LSG1 GNL2	3.57e-04	7	78	2	PS51721
Domain	MMR_HSR1	LSG1 GNL2	2.25e-03	17	78	2	PF01926
Domain	GTP_binding_domain	LSG1 GNL2	2.81e-03	19	78	2	IPR006073
Domain	SAP	DEK SF3B2	3.77e-03	22	78	2	PF02037
Domain	SAP	DEK SF3B2	4.12e-03	23	78	2	SM00513
Domain	SAP	DEK SF3B2	4.85e-03	25	78	2	PS50800
Domain	SAP_dom	DEK SF3B2	4.85e-03	25	78	2	IPR003034
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	NRBP1 HSP90B1 ATP6V0A1 INF2 CEBPZ ANP32B LSG1 CWC15 PIEZO1 CLNS1A PES1 GNL2 DNAJC21 CCDC97 TYW1 ITPRID2 SSR1 GNAS SSRP1 DEK SF3B2	1.07e-11	1487	79	21	33957083
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	RBBP5 LSG1 CWC15 G3BP2 PES1 ANKRD17 EIF3D HUWE1 SSRP1 SF3B2	2.98e-10	251	79	10	28077445
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	HSP90B1 ATP6V0A1 CEBPZ RBBP5 ANP32B LSG1 G3BP2 RGS22 PES1 LARS1 GNL2 EIF3D SSR1 GNAS HUWE1 SSRP1 DEK SF3B2	2.44e-09	1425	79	18	30948266
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	TRIM33 CEBPZ CWC15 PES1 CEP290 KIAA1958 HUWE1 SSRP1 DEK CDCA7L HELB	9.46e-09	469	79	11	27634302
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	HSP90B1 ERCC6 CEBPZ LSG1 CWC15 G3BP2 PES1 LARS1 GNL2 DNAJC21 ANKRD17 ITPRID2 EIF3D GNAS SSRP1 SF3B2	1.95e-08	1257	79	16	36526897
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	HSP90B1 CEBPZ LSG1 G3BP2 PES1 LARS1 GNL2 DNAJC21 ITPRID2 SSR1 GNAS SSRP1 DEK SF3B2	2.77e-08	949	79	14	36574265
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	TRIM33 NEK1 HSP90B1 ZFYVE27 RBBP5 LSG1 CWC15 G3BP2 ITPRID2 EIF3D PROSER2 SSR1 SSRP1 AKT1S1	5.76e-08	1007	79	14	34597346
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	HSP90B1 ERCC6 CEBPZ RBBP5 LSG1 G3BP2 PES1 GNL2 ANKRD17 SSRP1 DEK CDCA7L SF3B2	5.81e-08	847	79	13	35850772
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	TRIM33 MAP1B CEBPZ RBBP5 G3BP2 PES1 LARS1 ANKRD17 EIF3D SSR1 HUWE1 SSRP1	6.40e-08	704	79	12	29955894
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	HSP90B1 MAP1B CEBPZ PES1 CEP290 LARS1 GNL2 ITPRID2 EIF3D GNAS HUWE1 SSRP1 DEK SF3B2	7.07e-08	1024	79	14	24711643
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	NRBP1 NEK1 NEK3 MAP1B G3BP2 CLNS1A HUWE1 AKT1S1	9.46e-08	246	79	8	15345747
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	HSP90B1 MAP1B INF2 CEBPZ RBBP5 ANP32B G3BP2 PES1 LARS1 GNL2 ITPRID2 EIF3D GNAS HUWE1 SSRP1 DEK	1.26e-07	1440	79	16	30833792
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PPP4R3B NRBP1 TRIM33 CNKSR1 HSP90B1 ATP6V0A1 CEP290 PNMA2 LARS1 PAK2 EIF3D HUWE1 SF3B2 ZMYM5 RYR3	1.76e-07	1285	79	15	35914814
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	NEK1 HSP90B1 GTF2E1 MAP1B LSG1 CWC15 PES1 LARS1 GNL2 PAK2 ANKRD17 EIF3D SF3B2	1.79e-07	934	79	13	33916271
Pubmed	A comprehensive resource of interacting protein regions for refining human transcription factor networks.	HSP90B1 ARID4B MAP1B ANP32B DNAJC21 GNAS RYR3	2.80e-07	191	79	7	20195357
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	PPP4R3B CEBPZ RBBP5 LSG1 G3BP2 GNL2 ANKRD17 HUWE1 SSRP1	7.20e-07	440	79	9	34244565
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	HSP90B1 CEBPZ CWC15 PES1 LARS1 GNL2 EIF3D SSR1 SSRP1 DEK SF3B2	8.10e-07	731	79	11	29298432
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	PPP4R3B NRBP1 HSP90B1 GTF2E1 ANP32B CLNS1A PES1 PNMA2 LARS1 PAK2 EIF3D HUWE1 SSRP1 DEK AKT1S1	8.49e-07	1455	79	15	22863883
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	ERCC6 ARID4B MAP1B CEBPZ G3BP2 KAT6A LARS1 GNL2 DNAJC21 SSRP1 DEK	1.17e-06	759	79	11	35915203
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	GTF2E1 ERCC6 ARID4B RBBP5 PES1 KAT6A GNL2 SSRP1 DEK MIER1	1.21e-06	608	79	10	36089195
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PARD6B TRIM33 ERCC6 CEBPZ RBBP5 LSG1 PIEZO1 PES1 GNL2 DNAJC21 ANKRD17 ITPRID2 EIF3D SSR1 SSRP1	1.21e-06	1497	79	15	31527615
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	G3BP2 PES1 LARS1 GNL2 DNAJC21 ANKRD17 EIF3D GNAS SSRP1 SF3B2	1.34e-06	615	79	10	31048545
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	HSP90B1 MAP1B RBBP5 CWC15 G3BP2 CLNS1A PNMA2 LARS1 EIF3D SSR1 GNAS HUWE1 SSRP1 SF3B2	1.70e-06	1335	79	14	29229926
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	INF2 ANP32B CLNS1A SSRP1 DEK SF3B2	2.02e-06	163	79	6	22113938
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	TRIM33 HSP90B1 CEBPZ ANP32B LSG1 PES1 GNL2 EIF3D HUWE1 SSRP1 DEK SF3B2	2.33e-06	989	79	12	36424410
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	HSP90B1 GTF2E1 CEBPZ ANP32B LSG1 G3BP2 LARS1 GNL2 EIF3D SSR1 HUWE1 SSRP1 DEK SF3B2	3.34e-06	1415	79	14	28515276
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	TRIM33 ARID4B MAP1B RBBP5 PES1 LARS1 ANKRD17 BEND4 HUWE1 DEK SF3B2	3.75e-06	857	79	11	25609649
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PPP4R3B HSP90B1 GTF2E1 CEBPZ CLNS1A PES1 CEP290 PNMA2 GNL2 ITPRID2 HUWE1 DEK	4.25e-06	1049	79	12	27880917
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	HSP90B1 INF2 CEBPZ G3BP2 CLNS1A LARS1 DNAJC21 ANKRD17 EIF3D GNAS HUWE1 SSRP1 SF3B2	4.46e-06	1247	79	13	27684187
Pubmed	Light chain 1 of microtubule-associated protein 1B can negatively regulate the action of Pes1.	MAP1B PES1	5.09e-06	2	79	2	17308336
Pubmed	The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.	INF2 G3BP2 LARS1 DNAJC21 ANKRD17 PROSER2 MIER1	5.41e-06	298	79	7	30737378
Pubmed	ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis.	HSP90B1 ATP6V0A1 ZFYVE27 INF2 LSG1 TYW1 SSR1	5.53e-06	299	79	7	37931956
Pubmed	Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans.	NEK1 NEK3 MAP3K13	6.18e-06	16	79	3	8274451
Pubmed	A method to identify cDNAs based on localization of green fluorescent protein fusion products.	ANP32B KAT6A DEK	7.50e-06	17	79	3	10716735
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	PPP4R3B HSP90B1 CEBPZ CWC15 PES1 LARS1 GNL2 PAK2 EIF3D HUWE1 SSRP1 DEK SF3B2	8.08e-06	1318	79	13	30463901
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ARID4B KIAA1958 ANKRD17 ITPRID2 PROSER2 HUWE1 SSRP1 MIER1 AKT1S1 SF3B2	1.02e-05	774	79	10	15302935
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	HSP90B1 MAP1B ANP32B G3BP2 CLNS1A LARS1 ANKRD17 EIF3D GNAS HUWE1 SSRP1 SF3B2	1.06e-05	1149	79	12	35446349
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	HSP90B1 ERCC6 MAP1B INF2 CEBPZ LSG1 PES1 LARS1 ANKRD17 EIF3D HUWE1 SSRP1 SF3B2	1.07e-05	1353	79	13	29467282
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	INF2 CEBPZ PES1 GNL2 ITPRID2 HUWE1 SSRP1	1.09e-05	332	79	7	25693804
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	ARID4B CEBPZ G3BP2 CLNS1A GNL2 DNAJC21 ANKRD17 EIF3D GNAS HUWE1 SF3B2	1.21e-05	971	79	11	33306668
Pubmed	Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns.	CACNA1A EVA1C GNAS SSRP1	1.33e-05	63	79	4	17672918
Pubmed	A human MAP kinase interactome.	PARD6B HSP90B1 ARID4B CEP290 PAK2 ANKRD17 CCDC97 ITPRID2	1.50e-05	486	79	8	20936779
Pubmed	Differential alterations in expressions of ryanodine receptor subtypes in cerebellar cortical neurons of an ataxic mutant, rolling mouse Nagoya.	CACNA1A RYR3	1.53e-05	3	79	2	18313230
Pubmed	p21-activated kinase 2 binds to transcription factor SOX2 and up-regulates DEK to promote the progression of lung squamous cell carcinoma.	PAK2 DEK	1.53e-05	3	79	2	35821094
Pubmed	R1 Regulates Prostate Tumor Growth and Progression By Transcriptional Suppression of the E3 Ligase HUWE1 to Stabilize c-Myc.	HUWE1 CDCA7L	1.53e-05	3	79	2	30042175
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	PPP4R3B G3BP2 CLNS1A PES1 LARS1 GNL2 ANKRD17 GNAS SF3B2	1.80e-05	655	79	9	35819319
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	PPP4R3B TRIM33 GTF2E1 RBBP5 ANP32B PES1 PAK2 SSRP1 DEK CDCA7L SF3B2	1.81e-05	1014	79	11	32416067
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	CEBPZ LSG1 G3BP2 PNMA2 GNL2 DNAJC21 SF3B2	1.97e-05	364	79	7	24778252
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	CDKN3 ARID4B MAP1B GNL2 HUWE1 DEK	2.49e-05	253	79	6	29911972
Pubmed	Mechanosensory hair cells express two molecularly distinct mechanotransduction channels.	TMC1 PIEZO1	3.05e-05	4	79	2	27893727
Pubmed	Expression of the NEK family in normal and cancer tissue: an immunohistochemical study.	NEK1 NEK3	3.05e-05	4	79	2	31906878
Pubmed	KAT6A Acetylation of SMAD3 Regulates Myeloid-Derived Suppressor Cell Recruitment, Metastasis, and Immunotherapy in Triple-Negative Breast Cancer.	TRIM33 KAT6A	3.05e-05	4	79	2	34392614
Pubmed	The MAP1B-LC1/UBE2L3 complex catalyzes degradation of cell surface CaV2.2 channels.	CACNA1A MAP1B	3.05e-05	4	79	2	25483588
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	HSP90B1 MAP1B RBBP5 PES1 LARS1 CCDC97 SSRP1	3.27e-05	394	79	7	27248496
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	NEK1 MAP1B PES1 GNL2 ANKRD17 SSR1 GNAS HUWE1	3.49e-05	547	79	8	37267103
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	MAP1B ANP32B PAK2 EIF3D PROSER2 DEK SF3B2	3.54e-05	399	79	7	35987950
Pubmed	E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs.	MICAL1 PES1 PAK2	3.55e-05	28	79	3	30277474
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	HSP90B1 MAP1B G3BP2 CLNS1A LARS1 EIF3D HUWE1 SF3B2	3.67e-05	551	79	8	34728620
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	HSP90B1 MAP1B RBBP5 PES1 GNL2 FSD2 EIF3D	4.20e-05	410	79	7	26949251
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	CEBPZ LSG1 CWC15 PES1 CEP290 GNL2 TYW1 HUWE1 SF3B2	4.32e-05	733	79	9	34672954
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TRIM33 ERCC6 ARID4B LSG1 KAT6A PNMA2 GNL2 ANKRD17 SSRP1 TFDP2 BAHCC1	4.34e-05	1116	79	11	31753913
Pubmed	HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.	HSP90B1 MAP1B ANP32B LARS1 SSR1 GNAS HUWE1 SSRP1	4.72e-05	571	79	8	37167062
Pubmed	Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure.	PIEZO1 GNAS	5.07e-05	5	79	2	31205027
Pubmed	PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2.	PPARGC1B SF3B2	5.07e-05	5	79	2	33712605
Pubmed	The functional interactome landscape of the human histone deacetylase family.	ARID4B CEBPZ PES1 HUWE1 MIER1 SF3B2	5.22e-05	289	79	6	23752268
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	TRIM33 HSP90B1 CWC15 G3BP2 LARS1 GRIP2 PROSER2 SSRP1 SF3B2	5.36e-05	754	79	9	35906200
Pubmed	TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.	LSG1 G3BP2 PES1 GNAS SSRP1 DEK SF3B2	5.67e-05	430	79	7	38172120
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	PARD6B CEBPZ LSG1 CWC15 G3BP2 PES1 GNL2 ANKRD17 GNAS SSRP1 DEK SF3B2	5.98e-05	1371	79	12	36244648
Pubmed	High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization.	BNC2 DNAJC21 DEK TFDP2	6.44e-05	94	79	4	16325481
Pubmed	Revealing A-Raf functions through its interactome.	NEK1 HSP90B1 LARS1 SSR1 GNAS	6.96e-05	187	79	5	29777862
Pubmed	NIMA-related kinases: isolation and characterization of murine nek3 and nek4 cDNAs, and chromosomal localization of nek1, nek2 and nek3.	NEK1 NEK3	7.60e-05	6	79	2	10393247
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	HSP90B1 MAP1B INF2 CEBPZ G3BP2 ITPRID2 EIF3D SSRP1	8.94e-05	626	79	8	33644029
Pubmed	Noncanonical regulation of alkylation damage resistance by the OTUD4 deubiquitinase.	MAP1B CLNS1A SF3B2	9.72e-05	39	79	3	25944111
Pubmed	CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism.	GTF2E1 CLNS1A CCDC97 TYW1 SSRP1	9.77e-05	201	79	5	34917906
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	TRIM33 HSP90B1 PES1 LARS1 EIF3D HUWE1 SSRP1 SF3B2	1.02e-04	638	79	8	33239621
Pubmed	Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.	MAP1B G3BP2 LARS1 GNL2 SSRP1 DEK	1.16e-04	334	79	6	30425250
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	RBBP5 LSG1 G3BP2 CLNS1A EIF3D SSRP1 MIER1 SF3B2	1.20e-04	653	79	8	33742100
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MAP1B CEBPZ PES1 GNL2 ANKRD17 EIF3D HUWE1 SF3B2	1.20e-04	653	79	8	22586326
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	ERCC6 CEBPZ PIEZO1 MIER1 CDCA7L	1.20e-04	210	79	5	16565220
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	TRIM33 ANP32B PES1 GNL2 SSRP1 SF3B2	1.25e-04	339	79	6	30415952
Pubmed	A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.	BNC2 SKAP1	1.41e-04	8	79	2	20852632
Pubmed	Distinct strategies to make nucleosomal DNA accessible.	ERCC6 DEK	1.41e-04	8	79	2	12769854
Pubmed	Nuclear myosin 1 contributes to a chromatin landscape compatible with RNA polymerase II transcription activation.	ERCC6 DEK	1.41e-04	8	79	2	26044184
Pubmed	The Piezo channel is a mechano-sensitive complex component in the mammalian inner ear hair cell.	TMC1 PIEZO1	1.41e-04	8	79	2	38228630
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NEK1 MAP1B LSG1 ANKRD17 ITPRID2 PROSER2 GNAS SSRP1 AKT1S1	1.47e-04	861	79	9	36931259
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	MAP1B CEBPZ PES1 GNL2 ZNF428 HUWE1	1.47e-04	349	79	6	25665578
Pubmed	The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival.	LSG1 PES1 GNL2 ANKRD17 HUWE1	1.49e-04	220	79	5	31822558
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PPP4R3B NRBP1 G3BP2 PES1 PNMA2 LARS1 GNL2 PAK2 EIF3D GNAS SF3B2	1.51e-04	1284	79	11	17353931
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	HSP90B1 MAP1B LSG1 PES1 GNL2 EIF3D SSR1 SSRP1 DEK SF3B2	1.68e-04	1082	79	10	38697112
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	ERCC6 MAP1B PES1 CEP290 LARS1 HUWE1	1.69e-04	358	79	6	32460013
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	TRIM33 NEK1 MAP1B INF2 SKOR2 CEP290 KAT6A DNAJC21	1.73e-04	689	79	8	36543142
Pubmed	MLF2 Negatively Regulates P53 and Promotes Colorectal Carcinogenesis.	G3BP2 HUWE1 SSRP1	1.81e-04	48	79	3	37438558
Pubmed	The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription.	ERCC6 DEK	1.82e-04	9	79	2	16603771
Pubmed	Nuclear myosin 1c facilitates the chromatin modifications required to activate rRNA gene transcription and cell cycle progression.	ERCC6 DEK	1.82e-04	9	79	2	23555303
Pubmed	METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.	TRIM33 G3BP2 LARS1 GNAS RYR3	1.87e-04	231	79	5	36597993
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	HSP90B1 CWC15 LARS1 ANKRD17 EIF3D DEK SF3B2	2.26e-04	538	79	7	28524877
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	NRBP1 MICAL1 HSP90B1 INF2 CEBPZ RBBP5 EIF3D SSR1 AKT1S1 SF3B2	2.28e-04	1124	79	10	21900206
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	MAP1B CEBPZ LSG1 G3BP2 PAK2 DNAJC21 ANKRD17 EIF3D	2.41e-04	724	79	8	36232890
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	HSP90B1 MAP1B G3BP2 PES1 LARS1 GNL2 SSR1 SF3B2	2.43e-04	725	79	8	27025967
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	MAP1B INF2 CWC15 G3BP2 ANKRD17 EIF3D SSR1 GNAS HUWE1 SSRP1 SF3B2	2.59e-04	1367	79	11	32687490
Interaction	PYHIN1 interactions	MAP1B RBBP5 LSG1 CWC15 G3BP2 PES1 ANKRD17 EIF3D ZNF428 HUWE1 SSRP1 SF3B2	1.25e-08	358	78	12	int:PYHIN1
Interaction	CAND1 interactions	TRIM33 HSP90B1 ERCC6 TMC1 MAP1B G3BP2 PES1 CEP290 GNL2 DNAJC21 EIF3D SSR1 HUWE1 SSRP1 DEK SF3B2	2.55e-07	894	78	16	int:CAND1
Interaction	POLR1A interactions	HSP90B1 ERCC6 CEBPZ ANP32B LSG1 SKAP1 KAT6A SSRP1	2.16e-06	220	78	8	int:POLR1A
Interaction	HGH1 interactions	MAP1B CEBPZ LSG1 KAT6A GNL2	5.25e-06	65	78	5	int:HGH1
Interaction	GNL3 interactions	CEBPZ LSG1 G3BP2 PES1 KAT6A GNL2 DNAJC21 MAP3K13 SSRP1	1.23e-05	368	78	9	int:GNL3
Interaction	ING4 interactions	G3BP2 KAT6A GNL2 TRIM63 SSRP1	1.29e-05	78	78	5	int:ING4
Interaction	H2BC21 interactions	MICAL1 TMC1 ARID4B MAP1B RBBP5 KAT6A DNAJC21 HUWE1 SSRP1 DEK CDCA7L BAHCC1	1.41e-05	696	78	12	int:H2BC21
Interaction	CSNK2A1 interactions	HSP90B1 ARID4B INF2 RBBP5 ANP32B CLNS1A PES1 KAT6A MAP3K13 EIF3D ZNF428 SSRP1 DEK SF3B2	1.60e-05	956	78	14	int:CSNK2A1
Interaction	CSNK2A2 interactions	HSP90B1 ERCC6 ARID4B RBBP5 PES1 KAT6A EIF3D HUWE1 SSRP1 DEK AKT1S1 SF3B2	1.92e-05	718	78	12	int:CSNK2A2
Interaction	NAA40 interactions	NEK1 HSP90B1 GTF2E1 MAP1B LSG1 CWC15 PES1 LARS1 GNL2 PAK2 ANKRD17 EIF3D SSRP1 SF3B2	2.06e-05	978	78	14	int:NAA40
Interaction	FZR1 interactions	TRIM33 LRRC46 ARID4B MAP1B CEBPZ G3BP2 CLNS1A GNL2 DNAJC21 ANKRD17 EIF3D GNAS HUWE1 AKT1S1 SF3B2	3.69e-05	1172	78	15	int:FZR1
Interaction	H3C1 interactions	TRIM33 GTF2E1 ERCC6 ARID4B RBBP5 ANP32B PES1 CEP290 KAT6A GNL2 SSRP1 DEK SF3B2	3.89e-05	901	78	13	int:H3C1
Interaction	TTC4 interactions	CEBPZ LSG1 KAT6A GNL2 DNAJC21 HUWE1	4.34e-05	165	78	6	int:TTC4
Interaction	CTPS1 interactions	NRBP1 TRIM33 CEBPZ LSG1 CLNS1A GNL2 HUWE1	5.46e-05	252	78	7	int:CTPS1
Interaction	METTL14 interactions	TRIM33 HSP90B1 G3BP2 LARS1 SSR1 GNAS HUWE1 DEK SF3B2 RYR3	5.67e-05	558	78	10	int:METTL14
Interaction	TBL2 interactions	EVA1C EVA1B MAP1B SKAP1 KAT6A SSR1	6.22e-05	176	78	6	int:TBL2
Interaction	NOB1 interactions	G3BP2 CLNS1A KAT6A GNL2 HUWE1	8.75e-05	116	78	5	int:NOB1
Interaction	SUMO2 interactions	TRIM33 HSP90B1 ERCC6 ANP32B LARS1 TRIM63 HUWE1 SSRP1 SF3B2 ZMYM5	9.13e-05	591	78	10	int:SUMO2
Interaction	ALKBH3 interactions	MAP1B CLNS1A TRIM63 SF3B2	9.16e-05	61	78	4	int:ALKBH3
Interaction	CREBBP interactions	TRIM33 MAP1B RBBP5 CEP290 KAT6A EIF3D HUWE1 DEK MIER1 ZMYM5	1.02e-04	599	78	10	int:CREBBP
Interaction	DIS3 interactions	TRIM33 CEBPZ LSG1 ZNF428 GNAS HUWE1	1.06e-04	194	78	6	int:DIS3
Interaction	CEBPZ interactions	CEBPZ LSG1 PES1 KAT6A GNL2 DNAJC21 SF3B2	1.08e-04	281	78	7	int:CEBPZ
Interaction	PPIE interactions	GTF2E1 CEBPZ CWC15 TRIM63 HUWE1 SSRP1 SF3B2	1.10e-04	282	78	7	int:PPIE
Interaction	PNMA8A interactions	CEBPZ KAT6A PNMA2 GNL2 ANKRD17	1.11e-04	122	78	5	int:PNMA8A
Interaction	POLR1G interactions	GTF2E1 ARID4B CEBPZ SKAP1 PES1 KAT6A GNL2 HUWE1 SSRP1	1.12e-04	489	78	9	int:POLR1G
Interaction	RPL5 interactions	ERCC6 LSG1 G3BP2 KAT6A GNL2 ANKRD17 EIF3D SSR1 HUWE1 SSRP1	1.12e-04	606	78	10	int:RPL5
Interaction	HDAC2 interactions	ERCC6 ARID4B INF2 RBBP5 G3BP2 LARS1 DNAJC21 ANKRD17 PROSER2 HUWE1 DEK MIER1	1.16e-04	865	78	12	int:HDAC2
Interaction	ADNP interactions	MAP1B PNMA2 EIF3D HUWE1 SSRP1 MIER1	1.22e-04	199	78	6	int:ADNP
Interaction	CSNK2B interactions	CACNA1A NRBP1 MICAL1 ERCC6 RBBP5 KAT6A EIF3D SSRP1 DEK SF3B2	1.44e-04	625	78	10	int:CSNK2B
Interaction	H2AC4 interactions	MICAL1 ERCC6 RBBP5 PES1 LARS1 CCDC97 SSRP1 MIER1 SF3B2	1.45e-04	506	78	9	int:H2AC4
Interaction	MBD3 interactions	PPP4R3B HSP90B1 ERCC6 ARID4B RBBP5 EIF3D SSRP1	1.46e-04	295	78	7	int:MBD3
Interaction	F13B interactions	CEP290 DEK	1.47e-04	5	78	2	int:F13B
Interaction	DNAJC9 interactions	CEBPZ ANP32B PES1 KAT6A GNL2 SSRP1 DEK	1.49e-04	296	78	7	int:DNAJC9
Interaction	MEN1 interactions	HSP90B1 ERCC6 CEBPZ RBBP5 LSG1 G3BP2 PES1 GNL2 ANKRD17 SSRP1 DEK CDCA7L SF3B2	1.49e-04	1029	78	13	int:MEN1
Interaction	TRIM24 interactions	TRIM33 CNKSR1 HSP90B1 GTF2E1 ANKRD17 SSRP1 SF3B2 TFDP2	1.51e-04	398	78	8	int:TRIM24
Interaction	BIRC3 interactions	HSP90B1 CEBPZ RBBP5 ANP32B LSG1 G3BP2 PES1 LARS1 EIF3D SSR1 GNAS HUWE1 SSRP1 DEK SF3B2	1.59e-04	1334	78	15	int:BIRC3
Interaction	ANKRD1 interactions	CAPN3 TRIM63 CDCA7L	1.70e-04	28	78	3	int:ANKRD1
Interaction	TOP2A interactions	ERCC6 RBBP5 LSG1 CWC15 G3BP2 KAT6A DNAJC21 SSRP1 SF3B2	1.78e-04	520	78	9	int:TOP2A
Interaction	CAPN1 interactions	PPP4R3B CAPN3 LARS1 PAK2 ANKRD17 HUWE1	1.86e-04	215	78	6	int:CAPN1
Interaction	CCDC112 interactions	HSP90B1 FSD2 DEK	1.90e-04	29	78	3	int:CCDC112
Interaction	ANAPC5 interactions	TRIM33 GTF2E1 NEK3 INF2 HUWE1	1.98e-04	138	78	5	int:ANAPC5
Interaction	C7orf50 interactions	MAP1B CEBPZ G3BP2 GNL2 DNAJC21 HUWE1	2.01e-04	218	78	6	int:C7orf50
Interaction	TRMT1 interactions	CEBPZ LSG1 SKAP1 LARS1 GNL2	2.12e-04	140	78	5	int:TRMT1
Interaction	TNIP1 interactions	HSP90B1 CEBPZ LSG1 G3BP2 PES1 LARS1 GNL2 DNAJC21 ITPRID2 SSR1 GNAS SSRP1 DEK SF3B2	2.15e-04	1217	78	14	int:TNIP1
Interaction	RNF8 interactions	HSP90B1 MAP1B CWC15 PNMA2 FSD2 GRIP2 SSR1 SSRP1	2.22e-04	421	78	8	int:RNF8
Interaction	FOXK2 interactions	ARID4B MAP1B INF2 RBBP5 KAT6A ZNF428	2.38e-04	225	78	6	int:FOXK2
Interaction	H2AC14 interactions	MAP1B CEP290 DNAJC21 SSRP1 DEK	2.41e-04	144	78	5	int:H2AC14
Interaction	SRP9 interactions	ANP32B LSG1 LARS1 GNL2 ANKRD17 EIF3D HUWE1 SF3B2	2.44e-04	427	78	8	int:SRP9
Interaction	PDZD8 interactions	EVA1C HSP90B1 EVA1B ZFYVE27 LSG1 LARS1 EIF3D SSR1	2.48e-04	428	78	8	int:PDZD8
Interaction	CHAF1A interactions	ARID4B ANP32B KAT6A ANKRD17 EIF3D HUWE1 SSRP1	2.49e-04	322	78	7	int:CHAF1A
Interaction	NRP1 interactions	EVA1C EVA1B INF2 LSG1 GNAS SSRP1 DEK	2.59e-04	324	78	7	int:NRP1
Interaction	DOT1L interactions	HSP90B1 ERCC6 CEBPZ LSG1 G3BP2 PES1 GNL2 SSRP1 DEK CDCA7L SF3B2	2.66e-04	807	78	11	int:DOT1L
Interaction	DNAJC8 interactions	PES1 GNL2 CCDC97 HUWE1 SSRP1 SF3B2	2.68e-04	230	78	6	int:DNAJC8
Interaction	RPL7A interactions	CEBPZ G3BP2 PES1 KAT6A LARS1 GNL2 DNAJC21 SSR1 HUWE1 SF3B2	2.81e-04	679	78	10	int:RPL7A
Interaction	RECQL4 interactions	HSP90B1 MAP1B RBBP5 CWC15 G3BP2 SKAP1 CLNS1A PNMA2 LARS1 EIF3D SSR1 GNAS HUWE1 SSRP1 SF3B2	2.94e-04	1412	78	15	int:RECQL4
Interaction	MCRS1 interactions	RBBP5 KAT6A PNMA2 KIAA1958 FSD2 CDCA7L	3.01e-04	235	78	6	int:MCRS1
Interaction	NEK1 interactions	NEK1 SKAP1 CEP290 PNMA2	3.17e-04	84	78	4	int:NEK1
Interaction	H2BC9 interactions	HSP90B1 TMC1 MAP1B CEBPZ CEP290 DNAJC21 SSRP1 DEK	3.27e-04	446	78	8	int:H2BC9
Interaction	SKIC8 interactions	G3BP2 LARS1 GNL2 CCDC97 SSRP1 SF3B2	3.29e-04	239	78	6	int:SKIC8
Interaction	CAPRIN1 interactions	TRIM33 G3BP2 PES1 LARS1 DNAJC21 ANKRD17 SSR1 DEK	3.52e-04	451	78	8	int:CAPRIN1
Interaction	TGIF2LX interactions	ARID4B RBBP5 BAHCC1	3.63e-04	36	78	3	int:TGIF2LX
Interaction	CDC14B interactions	GTF2E1 CEBPZ PES1 GNL2 DEK	3.70e-04	158	78	5	int:CDC14B
Interaction	EED interactions	HSP90B1 ATP6V0A1 ARID4B MAP1B CEBPZ ANP32B PES1 CEP290 LARS1 TRIM63 PAK2 EIF3D HUWE1 SSRP1 DEK	3.77e-04	1445	78	15	int:EED
Interaction	HECTD1 interactions	ERCC6 ARID4B MAP1B CEBPZ G3BP2 KAT6A LARS1 GNL2 DNAJC21 HUWE1 SSRP1 DEK	3.80e-04	984	78	12	int:HECTD1
Interaction	SETX interactions	INF2 SKAP1 PNMA2 PAK2 SSRP1	3.81e-04	159	78	5	int:SETX
Interaction	MAFB interactions	RBBP5 LSG1 PES1 GNL2 ANKRD17 HUWE1	3.84e-04	246	78	6	int:MAFB
Interaction	EFTUD2 interactions	HSP90B1 GTF2E1 CEBPZ RBBP5 ANP32B LSG1 G3BP2 LARS1 GNL2 EIF3D SSR1 HUWE1 SSRP1 DEK SF3B2	3.88e-04	1449	78	15	int:EFTUD2
Interaction	SNRPD1 interactions	HSP90B1 ERCC6 CWC15 CLNS1A CCDC97 SSRP1 SF3B2	3.91e-04	347	78	7	int:SNRPD1
Interaction	IFI16 interactions	HSP90B1 MAP1B INF2 CEBPZ G3BP2 PES1 GNL2 ITPRID2 HUWE1 SSRP1	4.19e-04	714	78	10	int:IFI16
Interaction	PNMA2 interactions	EVA1C TRIM33 NEK1 ERCC6 CEP290 PNMA2	4.27e-04	251	78	6	int:PNMA2
Interaction	ASPM interactions	CNKSR1 HSP90B1 SKAP1 PNMA2 FSD2	4.39e-04	164	78	5	int:ASPM
Interaction	BRPF3 interactions	ARID4B PES1 KAT6A GNL2 BAHCC1	4.64e-04	166	78	5	int:BRPF3
Interaction	RPS16 interactions	LSG1 G3BP2 KAT6A LARS1 GNL2 DNAJC21 ANKRD17 EIF3D HUWE1 SF3B2	4.67e-04	724	78	10	int:RPS16
Interaction	PHAX interactions	HSP90B1 MAP1B G3BP2 HUWE1 SSRP1	4.77e-04	167	78	5	int:PHAX
Interaction	RBM8A interactions	LSG1 G3BP2 KAT6A GNL2 EIF3D SSRP1 DEK SF3B2	4.83e-04	473	78	8	int:RBM8A
Interaction	GSK3B interactions	NRBP1 MICAL1 NEK1 HSP90B1 MAP1B CEBPZ LSG1 PAK2 SSR1 SSRP1 HELB	4.94e-04	868	78	11	int:GSK3B
Interaction	DDX23 interactions	GTF2E1 ERCC6 MAP1B CEBPZ CWC15 PES1 GNL2 SSRP1	5.32e-04	480	78	8	int:DDX23
Interaction	PHF23 interactions	HSP90B1 ARID4B TRIM63	5.35e-04	41	78	3	int:PHF23
Interaction	ZC3H18 interactions	HSP90B1 CEBPZ CWC15 PES1 LARS1 GNL2 EIF3D SSR1 SSRP1 DEK SF3B2	5.38e-04	877	78	11	int:ZC3H18
Interaction	UFL1 interactions	HSP90B1 MAP1B G3BP2 CLNS1A PES1 GNL2 EIF3D SSR1 GNAS SSRP1 DEK SF3B2	5.76e-04	1031	78	12	int:UFL1
Interaction	PHF14 interactions	KAT6A SSRP1 DEK MIER1	6.14e-04	100	78	4	int:PHF14
Interaction	CENPA interactions	ERCC6 CEBPZ PES1 KAT6A GNL2 SSRP1 DEK	6.41e-04	377	78	7	int:CENPA
Interaction	ILF3 interactions	TRIM33 CEBPZ G3BP2 PES1 KAT6A GNL2 TRIM63 ANKRD17 SSR1 HUWE1 SSRP1	6.43e-04	896	78	11	int:ILF3
Interaction	DCAF4 interactions	HSP90B1 TMC1 CEBPZ RBBP5 GNL2 EIF3D SSRP1	6.51e-04	378	78	7	int:DCAF4
Interaction	RIMBP2 interactions	CACNA1A KAT6A	6.52e-04	10	78	2	int:RIMBP2
Interaction	SRP68 interactions	TRIM33 CEBPZ LSG1 G3BP2 GNL2 EIF3D HUWE1	6.82e-04	381	78	7	int:SRP68
Interaction	EIF4A3 interactions	ERCC6 MAP1B CWC15 CLNS1A HUWE1 SSRP1 CDCA7L SF3B2	6.86e-04	499	78	8	int:EIF4A3
Interaction	SIRT6 interactions	PPP4R3B CEBPZ RBBP5 LSG1 G3BP2 GNL2 ANKRD17 HUWE1 SSRP1	7.03e-04	628	78	9	int:SIRT6
Interaction	ESF1 interactions	CEBPZ LSG1 PES1 KAT6A GNL2	7.04e-04	182	78	5	int:ESF1
Interaction	EIF3M interactions	G3BP2 PNMA2 EIF3D HUWE1 SSRP1	7.04e-04	182	78	5	int:EIF3M
Interaction	RPL4 interactions	CEBPZ LSG1 G3BP2 PES1 KAT6A GNL2 DNAJC21 EIF3D SSR1 HUWE1	7.08e-04	764	78	10	int:RPL4
Interaction	SMARCC1 interactions	TRIM33 HSP90B1 GTF2E1 ARID4B RBBP5 SSRP1 DEK	7.14e-04	384	78	7	int:SMARCC1
Interaction	H2BC26 interactions	MAP1B CEBPZ HUWE1 SSRP1 MIER1	7.22e-04	183	78	5	int:H2BC26
Interaction	MYCN interactions	NEK1 HSP90B1 MAP1B CEBPZ CWC15 G3BP2 PES1 GNL2 DNAJC21 ANKRD17 HUWE1 SSRP1 DEK SF3B2	7.24e-04	1373	78	14	int:MYCN
Interaction	FBXW7 interactions	HSP90B1 GTF2E1 ARID4B CEBPZ ANP32B PES1 LARS1 DNAJC21 EIF3D HUWE1 SSRP1 DEK SF3B2	7.36e-04	1215	78	13	int:FBXW7
Interaction	DRG1 interactions	MAP1B LSG1 G3BP2 PES1 GNL2 SSR1 HUWE1	7.59e-04	388	78	7	int:DRG1
Interaction	COMMD4 interactions	CCDC97 SSRP1 SF3B2 TFDP2	7.65e-04	106	78	4	int:COMMD4
Interaction	RXFP3 interactions	HSP90B1 GNAS	7.95e-04	11	78	2	int:RXFP3
Interaction	SUZ12 interactions	CWC15 G3BP2 PES1 CEP290 KIAA1958 SSRP1 CDCA7L SF3B2 HELB	8.40e-04	644	78	9	int:SUZ12
Interaction	RPN2 interactions	HSP90B1 ZFYVE27 INF2 LSG1 G3BP2 KAT6A TYW1 EIF3D SSR1 HUWE1	8.46e-04	782	78	10	int:RPN2
Coexpression	NAKAYA_MYELOID_DENDRITIC_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_DN	NEK1 ATP6V0A1 PAK2 ANKRD17 HUWE1 SSRP1 TFDP2	1.71e-05	269	79	7	M41203
Coexpression	GSE14308_NAIVE_CD4_TCELL_VS_NATURAL_TREG_DN	ANP32B SKAP1 KIAA1958 FSD2 DRC1 HELB	3.20e-05	200	79	6	M3394
Coexpression	GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_COLON_TUMOR_UP	CDKN3 DNAJC21 FSD2 PROSER2 MIER1 TFDP2	3.20e-05	200	79	6	M8085
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	PPP4R3B TRIM33 MICAL1 ARID4B ANP32B PIEZO1 G3BP2 SKAP1 KAT6A PAK2 GNAS HUWE1 DEK MIER1 ZMYM5	3.41e-05	1492	79	15	M40023
ToppCell	severe\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HSP90B1 ANP32B PAK2 GNAS DEK MIER1 SF3B2	6.83e-08	200	79	7	accc618d6b960bff30cb531c1226295bfc8650f6
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDKN3 BNC2 GLT8D2 MAP1B RGS22 BEND4	1.39e-06	197	79	6	6806ec223e542f0475303698eb78c1cc527f5c6b
ToppCell	LPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CDKN3 GLT8D2 TMC1 LSG1 PROSER2	8.88e-06	157	79	5	bd45590da540a557dc8096980a45220fccb99505
ToppCell	LPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CDKN3 GLT8D2 TMC1 LSG1 PROSER2	8.88e-06	157	79	5	00c9a58b033b8b95b0d838f233dd077b62d8b02a
ToppCell	NS-moderate-d_07-13-Lymphoid-NK\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAP1B AEBP1 CAPN3 PNMA2 TRIM63	1.50e-05	175	79	5	f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCell	droplet-Lung-LUNG-1m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVA1C CNKSR1 MAP1B BEND4 PROSER2	2.01e-05	186	79	5	e52cf44989c57c433bf82e9fa13b4643e88f3577
ToppCell	droplet-Lung-LUNG-1m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVA1C CNKSR1 MAP1B BEND4 PROSER2	2.01e-05	186	79	5	4c0b59d845b79323e7a3287e7c4d249f5f322556
ToppCell	Epithelial-Epithelial-D_(Ciliated)\|Epithelial / shred on cell class and cell subclass (v4)	NEK1 MAP1B RGS22 CEP290 DRC1	2.12e-05	188	79	5	8f30535a32968a81a304315a49c0d90a77d36948
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	CNKSR1 PIEZO1 PAK2 ITPRID2 CDCA7L	2.46e-05	194	79	5	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	CNKSR1 PIEZO1 PAK2 ITPRID2 CDCA7L	2.46e-05	194	79	5	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	Control-Neu_4\|Control / 5 Neutrophil clusters in COVID-19 patients	HSP90B1 ANP32B CEP290 EIF3D CDCA7L	2.59e-05	196	79	5	b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCell	droplet-Marrow-BM-1m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN3 ANP32B DNAJC21 ZNF428 DEK	2.59e-05	196	79	5	ef1482f83872af72a55b6c5b5a1491e6f7f44dd7
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic-granulocyte\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CDKN3 HSP90B1 ANP32B DEK BAHCC1	2.72e-05	198	79	5	2e669da80363163b806f23a645474d482797ae5d
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	HSP90B1 ARID4B G3BP2 GNAS MIER1	2.85e-05	200	79	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	B_cell_maturation-pre-B\|World / Lineage and Cell class	CDKN3 AEBP1 CDCA7L TFDP2 BAHCC1	2.85e-05	200	79	5	acb9ad7e3c05ec38e9700fb27b6eed8eaa565689
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors_nGenesUnder4k\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	CDKN3 HSP90B1 ANP32B SSRP1 DEK	2.85e-05	200	79	5	243c7f88befd402a57e9226706811c802b28e3fd
Computational	Neighborhood of EIF3S2	HSP90B1 CEBPZ G3BP2 CLNS1A EIF3D HUWE1 SSRP1 DEK	1.15e-05	246	48	8	MORF_EIF3S2
Computational	Neighborhood of HDAC2	CEBPZ G3BP2 CLNS1A GNL2 ANKRD17 SSRP1 DEK	2.23e-04	280	48	7	MORF_HDAC2
Computational	Neighborhood of AATF	CEBPZ CLNS1A GNL2 HUWE1 SSRP1 DEK	3.12e-04	209	48	6	MORF_AATF
Computational	Neighborhood of CSNK1A1	ARID4B LARS1 ANKRD17	5.38e-04	36	48	3	GCM_CSNK1A1
Disease	quality of life during menstruation measurement, breast pressure measurement	MAP1B ANKRD17	9.50e-05	6	75	2	EFO_0009366, EFO_0009393
Disease	keratinocyte carcinoma	PARD6B BNC2 PPARGC1B RGS22	2.37e-04	118	75	4	EFO_0010176
Disease	ovarian neoplasm	LRRC46 BNC2 ERCC6 SKAP1	3.85e-04	134	75	4	C0919267
Disease	Malignant neoplasm of ovary	LRRC46 BNC2 ERCC6 SKAP1	4.19e-04	137	75	4	C1140680
Disease	arterial stiffness measurement	BNC2 MAP3K13 ZMYM5	5.88e-04	64	75	3	EFO_0004517
Disease	skin neoplasm	PARD6B BNC2 RGS22	8.98e-04	74	75	3	EFO_0004198
Disease	freckles	BNC2 PPARGC1B	1.18e-03	20	75	2	EFO_0003963
Disease	basal cell carcinoma	PARD6B BNC2 PPARGC1B RGS22	1.39e-03	189	75	4	EFO_0004193
Disease	sunburn	BNC2 PPARGC1B CEP290	1.90e-03	96	75	3	EFO_0003958
Disease	Vitiligo	PPP4R3B PPARGC1B ATP8B1	2.20e-03	101	75	3	EFO_0004208

Protein segments in the cluster

Peptide	Gene	Start	Entry
IGIDVEDEDSDEDEF	CACNA1A	1716	O00555
KEDNSSEEEEEIEPF	ARID4B	291	Q4LE39
NSSFSEEEEDEEEEE	BAHCC1	1871	Q9P281
EDNEEDEDEPTETET	AKT1S1	101	Q96B36
IIDTADEFDDEDDDP	BNC2	646	Q6ZN30
EFETQLEPEFEEEEE	AEBP1	1116	Q8IUX7
SSSTLPEEEEEEDEE	BEND4	306	Q6ZU67
DDEVSEEEEEFGLDE	ANP32B	206	Q92688
DDPLTDEEDEDFEEE	CWC15	106	Q9P013
DDDDEEEEVSEVESF	ANKRD17	121	O75179
ESEYFPTEEEEEEED	ERCC6	371	Q03468
VVPYSDDETEDELDD	ATP8B1	21	O43520
EPSFEPEDEDSEEDD	PARD6B	281	Q9BYG5
PEDEDSEEDDIIIED	PARD6B	286	Q9BYG5
ESEYFPTEEEEEEED	ERCC6	371	P0DP91
EEELESFSDEEEEEQ	GNL2	556	Q13823
DYEEKAETEEAEEPE	MAP1B	941	P46821
DEDDSEYEDCPEEEE	LSG1	301	Q9H089
PSDSEDIVFEETDTD	NEK1	1091	Q96PY6
AFEEYSADVEEEEPE	MTURN	106	Q8N3F0
DEEERYFDEEEPEDA	CCDC97	321	Q96F63
SEEEEEDVPLDSDVE	MICAL1	876	Q8TDZ2
DADDESETPEELEEE	GLT8D2	36	Q9H1C3
DEEDEASSDEEFPEL	LRRC46	176	Q96FV0
VSEEEEDEEEDKATP	CDCA7L	116	Q96GN5
EEEASFENESIEEPE	PNMA2	336	Q9UL42
DYPDDEEEDEEEESS	PPP4R3B	826	Q5MIZ7
EELESVLEEEVDDFP	DNAJC21	121	Q5F1R6
AAEEASSEDEEEEEV	HUWE1	721	Q7Z6Z7
ATTQDEEEDEEEDLP	ITPRID2	46	P28290
EEEEAEEAAAEPESY	DRC1	466	Q96MC2
DEDEDEEDTAPESAL	INF2	1171	Q27J81
EPGLDEEDTDFEEED	NEK3	471	P51956
EFDIEDEDKSEPEQT	RBBP5	351	Q15291
ASPEEEEESEDESEI	NRBP1	41	Q9UHY1
EEESEDESEILEESP	NRBP1	46	Q9UHY1
SEEEEGEVDSEVEFP	MAP3K13	816	O43283
EEPEETAEDTTEDTE	HSP90B1	761	P14625
LEPTFEIDEEEEEED	KAT6A	1061	Q92794
AVVTEEEDDDEETAP	PAK2	166	Q13177
DSEDEEEEEDPSESD	EVA1C	371	P58658
STLEPEDDDEDEEDT	EVA1B	71	Q9NVM1
FEEESKEPVADEEEE	CLNS1A	86	P54105
DEEEEDSDDDVEPIT	CLNS1A	96	P54105
PEDAEATVEEEVYDD	CARD6	221	Q9BX69
AASEEFEDEEESPVN	CEP290	2461	O15078
SEPELDEESEDEVEE	G3BP2	141	Q9UN86
EESSDDEDKESEEEP	DEK	241	P35659
TFSSDEDEEEEEEEE	EIF3D	526	O15371
ESEIESETDFETEPE	GNAS	116	O95467
DESFPEEEEEDDWEP	GRIP2	841	Q9C0E4
EEDDDPDDSEVICSF	CAPN3	466	P20807
EFDSSDEEPIEDEQT	CDKN3	11	Q16667
DDVEEDEESVFIDAE	HELB	31	Q8NG08
AVEDPDEEDEDNTSE	CEBPZ	21	Q03701
ADEESIEDVDDEEFE	CEBPZ	831	Q03701
FDTNSEVEEESEEDE	MIER1	156	Q8N108
EVEEESEEDEDYIPS	MIER1	161	Q8N108
EEEDDEFEEVADDPI	GTF2E1	381	P29083
EDDGEVTEDSDEDFI	TRIM33	1096	Q9UPN9
DDEAEVEEDEPTDLV	SSR1	51	P43307
SEFEEEEGEEEEVSV	RGS22	266	Q8NE09
EETIDSLDEDFEEPV	PROSER2	66	Q86WR7
DFPDEEEEEEETSVK	LARS1	116	Q9P2J5
IPEEEDEEEAADVFC	FSD2	166	A1L4K1
ESSFLPEEEEEEGEE	PPARGC1B	801	Q86YN6
TPCSFNDEDEEDDEE	TFDP2	426	Q14188
EETDESFNPGEEEED	SSRP1	476	Q08945
ETEESSSEEEEEVED	TMC1	16	Q8TDI8
EDCYSETEAEDPDDE	CNKSR1	516	Q969H4
EEFIEEEDQEEEEST	TRIM63	331	Q969Q1
TLSEPDSEEEEDEEE	ZNF428	36	Q96B54
EFSEPEEEIDENEEI	TNMD	131	Q9H2S6
LEPSDEESSEEEEEE	SF3B2	711	Q13435
TEEEAEVDEFPTDGE	PES1	291	O00541
PEEEEEDEDSSYVLE	RYR3	4111	Q15413
YPSEDSSEDEDDEEE	SKOR2	726	Q2VWA4
DADEPSEDEVFDFGD	ATP6V0A1	701	Q93050
VEDDDDDDDVVFIES	ZMYM5	51	Q9UJ78
EEAEEAEPDEEFKDA	ZFYVE27	276	Q5T4F4
FESDSEEEEEAVPED	PIEZO1	1421	Q92508
TEEEEPFESSSEEEF	TYW1	286	Q9NV66
PEIAAEEEAYEEDAD	PRR23C	146	Q6ZRP0
EEEDIYEVLPDEEHD	SKAP1	266	Q86WV1
SEPSELDETVEEYED	KIAA1958	126	Q8N8K9