Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	carbon-sulfur lyase activity	CENPVL2 CENPVL3 CENPVL1	5.41e-05	16	94	3	GO:0016846
GeneOntologyMolecularFunction	DNA-directed DNA polymerase activity	POLE POLI POLQ	2.16e-04	25	94	3	GO:0003887
Domain	-	AP2A1 AP2A2	2.35e-05	2	91	2	2.60.40.1030
Domain	AP2_complex_asu	AP2A1 AP2A2	2.35e-05	2	91	2	IPR017104
Domain	Clathrin_a-adaptin_app_sub_C	AP2A1 AP2A2	2.35e-05	2	91	2	IPR003164
Domain	Clathrin_a-adaptin_app_Ig-like	AP2A1 AP2A2	2.35e-05	2	91	2	IPR013038
Domain	Alpha_adaptin_C	AP2A1 AP2A2	2.35e-05	2	91	2	PF02296
Domain	zf-C2H2	HIVEP1 ZNF280D TSHZ2 ZNF429 MECOM ZNF208 ZNF510 ZBTB24 PRDM2 ZNF117 ZNF90 ZNF426	1.33e-04	693	91	12	PF00096
Domain	-	AP2A1 AP2A2	1.40e-04	4	91	2	3.30.310.30
Domain	Clathrin_a/coatomer_app_sub_C	AP2A1 AP2A2	1.40e-04	4	91	2	IPR015873
Domain	zf-C2H2_6	ZNF429 MECOM ZNF208 ZBTB24 PRDM2 ZNF117 ZNF90 ZNF426	1.48e-04	314	91	8	PF13912
Domain	CLTH	RMND5B RMND5A	3.48e-04	6	91	2	PF10607
Domain	CRA	RMND5B RMND5A	3.48e-04	6	91	2	SM00757
Domain	CTLH/CRA	RMND5B RMND5A	3.48e-04	6	91	2	IPR024964
Domain	CRA_dom	RMND5B RMND5A	3.48e-04	6	91	2	IPR013144
Domain	ZINC_FINGER_C2H2_2	HIVEP1 ZNF280D TSHZ2 ZNF429 MECOM ZNF208 ZNF510 ZBTB24 PRDM2 ZNF117 ZNF90 ZNF426	3.72e-04	775	91	12	PS50157
Domain	ZINC_FINGER_C2H2_1	HIVEP1 ZNF280D TSHZ2 ZNF429 MECOM ZNF208 ZNF510 ZBTB24 PRDM2 ZNF117 ZNF90 ZNF426	3.81e-04	777	91	12	PS00028
Domain	Znf_C2H2-like	HIVEP1 ZNF280D TSHZ2 ZNF429 MECOM ZNF208 ZNF510 ZBTB24 PRDM2 ZNF117 ZNF90 ZNF426	4.73e-04	796	91	12	IPR015880
Domain	Znf_C2H2	HIVEP1 ZNF280D TSHZ2 ZNF429 MECOM ZNF208 ZNF510 ZBTB24 PRDM2 ZNF117 ZNF90 ZNF426	5.23e-04	805	91	12	IPR007087
Domain	ZnF_C2H2	HIVEP1 ZNF280D TSHZ2 ZNF429 MECOM ZNF208 ZNF510 ZBTB24 PRDM2 ZNF117 ZNF90 ZNF426	5.41e-04	808	91	12	SM00355
Domain	Coatomer/calthrin_app_sub_C	AP2A1 AP2A2	6.45e-04	8	91	2	IPR009028
Domain	CTLH	RMND5B RMND5A	8.27e-04	9	91	2	SM00668
Domain	Clathrin_a/b/g-adaptin_app_Ig	AP2A1 AP2A2	8.27e-04	9	91	2	IPR008152
Domain	Alpha_adaptinC2	AP2A1 AP2A2	8.27e-04	9	91	2	PF02883
Domain	Alpha_adaptinC2	AP2A1 AP2A2	8.27e-04	9	91	2	SM00809
Domain	DUF1220	NBPF4 NBPF6	8.27e-04	9	91	2	SM01148
Domain	CTLH_C	RMND5B RMND5A	1.03e-03	10	91	2	IPR006595
Domain	CTLH	RMND5B RMND5A	1.03e-03	10	91	2	PS50897
Domain	NBPF_dom	NBPF4 NBPF6	1.25e-03	11	91	2	IPR010630
Domain	NBPF	NBPF4 NBPF6	1.25e-03	11	91	2	PS51316
Domain	DUF1220	NBPF4 NBPF6	1.25e-03	11	91	2	PF06758
Domain	Coatomer/clathrin_app_Ig-like	AP2A1 AP2A2	1.50e-03	12	91	2	IPR013041
Domain	-	HIVEP1 ZNF429 MECOM ZNF208 ZNF510 ZBTB24 PRDM2 ZNF117 ZNF90 ZNF426	1.71e-03	679	91	10	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	HIVEP1 ZNF429 MECOM ZNF208 ZNF510 ZBTB24 PRDM2 ZNF117 ZNF90 ZNF426	2.01e-03	694	91	10	IPR013087
Domain	Clathrin/coatomer_adapt-like_N	AP2A1 AP2A2	2.37e-03	15	91	2	IPR002553
Domain	Adaptin_N	AP2A1 AP2A2	2.37e-03	15	91	2	PF01602
Domain	RasGEFN	RAPGEF6 RASGRP3	4.21e-03	20	91	2	SM00229
Domain	RasGEF_N	RAPGEF6 RASGRP3	4.64e-03	21	91	2	PF00618
Domain	Ras-like_Gua-exchang_fac_N	RAPGEF6 RASGRP3	5.09e-03	22	91	2	IPR000651
Domain	RASGEF_NTER	RAPGEF6 RASGRP3	5.09e-03	22	91	2	PS50212
Domain	Znf_RING/FYVE/PHD	RMND5B RMND5A PCLO MLLT10 WDR59 BRCA1 USP33	7.11e-03	459	91	7	IPR013083
Domain	AT_hook	ZBTB24 BOD1L1	7.61e-03	27	91	2	SM00384
Domain	AT_hook_DNA-bd_motif	ZBTB24 BOD1L1	7.61e-03	27	91	2	IPR017956
Domain	LisH	RMND5B RMND5A	8.17e-03	28	91	2	SM00667
Domain	LisH	RMND5B RMND5A	8.17e-03	28	91	2	IPR006594
Domain	LISH	RMND5B RMND5A	8.17e-03	28	91	2	PS50896
Domain	RASGEF_CAT	RAPGEF6 RASGRP3	8.75e-03	29	91	2	PS50009
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RAPGEF6 HIVEP1 CEP192 RAB11FIP1 WNK1 TRIP11 ERBIN WDR59 MDN1 AKAP9 KIAA1217 NAV1 BOD1L1 PIBF1 DOP1A	2.22e-08	861	99	15	36931259
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SYNE1 DOCK10 CEP192 ERBIN AKAP9 NAV1 RIPOR1 KATNIP BOD1L1 USP33	2.66e-07	407	99	10	12693553
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CASP8AP2 SYNE1 DOCK10 WNK1 ERBIN ZBTB24 AP2A2 UNC80	2.80e-07	225	99	8	12168954
Pubmed	Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow.	CENPVL2 CENPVL3 CENPVL1	4.45e-07	6	99	3	27250503
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	IL12RB1 OXR1 SYNE1 PCLO TRIP11 ERBIN NWD2 AP2A1 AP2A2 MTHFD1 KIAA1217 VCAN GKAP1 UGP2 NAV1 WDR1 HNRNPR	5.71e-07	1431	99	17	37142655
Pubmed	Functional proteomics mapping of a human signaling pathway.	RMND5B HIVEP1 RMND5A PPIL4 ZNF510 TRIM29 ERBIN AP2A1 AP2A2 POLI SPARCL1	1.02e-06	591	99	11	15231748
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	HIVEP1 POLE PPIL4 POM121C BRCA1 CLSPN	1.05e-06	116	99	6	30804394
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	RAPGEF6 HIVEP1 GCFC2 MECOM NBPF6 URGCP DNAH14 AP2A2 UGP2 POLI OSBP2 WDR1 FILIP1L	2.30e-06	925	99	13	28986522
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	HIVEP1 ZNF280D SYNE1 POLE PCLO PPIL4 CMYA5 PRDM2 MDN1 GTF3C1 AP2A1 AP2A2 MTHFD1 MKI67 BOD1L1 HNRNPR	2.65e-06	1425	99	16	30948266
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	IL12RB1 SYNE1 PCLO SPG11 ERBIN MDN1 GTF3C1 BRCA1 AP2A1 AP2A2 UGP2 BOD1L1 SPAG17 POLQ DOP1A HNRNPR	3.09e-06	1442	99	16	35575683
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	RMND5B RMND5A RAB11FIP1 POM121C WNK1 TRIP11 URGCP AP2A1 AP2A2 GKAP1 NAV1 RIPOR1 KATNIP PIBF1 CEP97	4.93e-06	1321	99	15	27173435
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RAPGEF6 CEP192 RAB11FIP1 WNK1 AKAP9 AP2A1 AP2A2 NAV1 PIBF1	5.41e-06	446	99	9	24255178
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CASP8AP2 HIVEP1 MECOM CEP192 WNK1 TRIP11 KIAA1217 NAV1 CLSPN HNRNPR	7.15e-06	588	99	10	38580884
Pubmed	A beta-turn endocytic code is required for optimal internalization of the growth hormone receptor but not for alpha-adaptin association.	GHR AP2A1	8.02e-06	2	99	2	10551776
Pubmed	Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation.	BRCA1 CLSPN	8.02e-06	2	99	2	15096610
Pubmed	Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins).	AP2A1 AP2A2	8.02e-06	2	99	2	2564002
Pubmed	Cloning, physical mapping and structural characterization of the human alpha(A)-adaptin gene.	AP2A1 AP2A2	8.02e-06	2	99	2	12036598
Pubmed	Structure and regulation of the versican promoter: the versican promoter is regulated by AP-1 and TCF transcription factors in invasive human melanoma cells.	TCF7L2 VCAN	8.02e-06	2	99	2	19269971
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SYNE1 ERBIN NWD2 KIAA1217 NAV1	1.18e-05	103	99	5	10574462
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	IP6K1 POM121C WNK1 WDR59 AP2A2 RASGRP3 POM121B UNC80 DOP1A	1.20e-05	493	99	9	15368895
Pubmed	Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins.	CEP192 BRCA1 MKI67	1.22e-05	16	99	3	29764992
Pubmed	Human transcription factor protein interaction networks.	TCF7L2 HIVEP1 PPIL4 MECOM CEP192 MLLT10 POM121C ERBIN PRDM2 GTF3C1 BRCA1 MKI67 WDR1 FILIP1L HNRNPR	1.26e-05	1429	99	15	35140242
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	HIVEP1 SYNE1 CMYA5 WNK1 TRIP11 AKAP9 UGP2 ZNF426 HNRNPR	1.28e-05	497	99	9	23414517
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RAPGEF6 HIVEP1 GCFC2 ERBIN URGCP PRDM2 MYO3A MDN1 GTF3C1 MKI67 RIPOR1	1.32e-05	774	99	11	15302935
Pubmed	Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses.	AP2A1 AP2A2	2.40e-05	3	99	2	35014951
Pubmed	A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2.	AP2A1 AP2A2	2.40e-05	3	99	2	18032517
Pubmed	Predicting Lymph Node Metastasis in Endometrial Cancer Using Serum CA125 Combined with Immunohistochemical Markers PR and Ki67, and a Comparison with Other Prediction Models.	MUC16 MKI67	2.40e-05	3	99	2	27163153
Pubmed	POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation.	POM121C POM121B	2.40e-05	3	99	2	30802453
Pubmed	Translesion synthesis DNA polymerases promote error-free replication through the minor-groove DNA adduct 3-deaza-3-methyladenine.	POLI POLQ	2.40e-05	3	99	2	28939775
Pubmed	BRCA1, Ki67, and β-Catenin Immunoexpression Is Not Related to Differentiation, Platinum Response, or Prognosis in Women With Low- and High-Grade Serous Ovarian Carcinoma.	BRCA1 MKI67	2.40e-05	3	99	2	29465506
Pubmed	Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.	POM121C POM121B	2.40e-05	3	99	2	35507432
Pubmed	Ki-67 and p53 expression of the fallopian tube mucosa in breast cancer patients with hereditary risk.	BRCA1 MKI67	2.40e-05	3	99	2	24196303
Pubmed	Genetic control of predominantly error-free replication through an acrolein-derived minor-groove DNA adduct.	POLI POLQ	2.40e-05	3	99	2	29330301
Pubmed	Single cell RNA analysis of the left-right organizer transcriptome reveals potential novel heterotaxy genes.	SYNE1 SPARCL1	2.40e-05	3	99	2	37393374
Pubmed	AP2 adaptor complex mediates bile salt export pump internalization and modulates its hepatocanalicular expression and transport function.	AP2A1 AP2A2	2.40e-05	3	99	2	22262466
Pubmed	Envelope Glycoprotein Internalization Protects Human and Simian Immunodeficiency Virus-Infected Cells from Antibody-Dependent Cell-Mediated Cytotoxicity.	AP2A1 AP2A2	2.40e-05	3	99	2	26269175
Pubmed	A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex.	AP2A1 AP2A2	2.40e-05	3	99	2	19129443
Pubmed	Prediction of BRCA1 germ-line mutation status in patients with breast cancer using histoprognosis grade, MS110, Lys27H3, vimentin, and KI67.	BRCA1 MKI67	2.40e-05	3	99	2	23614934
Pubmed	Interaction of Shc with adaptor protein adaptins.	AP2A1 AP2A2	2.40e-05	3	99	2	8617812
Pubmed	The ear of alpha-adaptin interacts with the COOH-terminal domain of the Eps 15 protein.	AP2A1 AP2A2	2.40e-05	3	99	2	8662627
Pubmed	Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4.	TCF7L2 MKI67	2.40e-05	3	99	2	9697701
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	CASP8AP2 RAPGEF6 HIVEP1 ZNF280D MECOM PRDM2 GTF3C1 NAV1	2.69e-05	418	99	8	34709266
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF4 NBPF6 NBPF5P	2.87e-05	21	99	3	16079250
Pubmed	USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification.	RAPGEF6 ERBIN AP2A1 AP2A2	3.04e-05	62	99	4	31340145
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	GCFC2 GPATCH1 ERBIN GTF3C1 AP2A1 AP2A2	3.61e-05	215	99	6	35973513
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	RAPGEF6 PPIL4 RAB11FIP1 TRIM29 WNK1 ERBIN AP2A1 KIAA1217 RIPOR1 KATNIP CLSPN CEP97	3.99e-05	1038	99	12	26673895
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	PPIL4 MDN1 BRCA1 AP2A1 AP2A2 POLQ	4.32e-05	222	99	6	37071664
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	GCFC2 MECOM SPG11 WNK1 ERBIN WDR59 NAV1 BOD1L1 CLSPN USP33	4.69e-05	733	99	10	34672954
Pubmed	A DNA-damage selective role for BRCA1 E3 ligase in claspin ubiquitylation, CHK1 activation, and DNA repair.	BRCA1 CLSPN	4.79e-05	4	99	2	22863316
Pubmed	Disruption of the murine Ap2β1 gene causes nonsyndromic cleft palate.	AP2A1 AP2A2	4.79e-05	4	99	2	20500056
Pubmed	Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes.	POM121C POM121B	4.79e-05	4	99	2	17900573
Pubmed	A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair.	BRCA1 MKI67	4.79e-05	4	99	2	34548335
Pubmed	The B cell coreceptor CD22 associates with AP50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction.	AP2A1 AP2A2	4.79e-05	4	99	2	12646615
Pubmed	A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage.	BRCA1 MKI67	4.79e-05	4	99	2	11420664
Pubmed	Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells.	SYNE1 AKAP9	4.79e-05	4	99	2	28966089
Pubmed	Association and colocalization of Eps15 with adaptor protein-2 and clathrin.	AP2A1 AP2A2	4.79e-05	4	99	2	9049247
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	TCF7L2 HIVEP1 ZNF280D ZBTB24 PRDM2 GTF3C1 BRCA1 MKI67 BOD1L1	6.16e-05	608	99	9	36089195
Pubmed	Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity.	CEP192 PIBF1 CEP97	6.23e-05	27	99	3	35709258
Pubmed	Interaction network of human early embryonic transcription factors.	TCF7L2 HIVEP1 MECOM POM121C PRDM2 ASXL3 MKI67	6.75e-05	351	99	7	38297188
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	RAPGEF6 GPATCH1 POM121C WNK1 TRIP11 ERBIN MTHFD1 KIAA1217 MKI67 BOD1L1 WDR1	7.25e-05	934	99	11	33916271
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RAPGEF6 POLE CEP192 MLLT10 POM121C WNK1 WDR59 MDN1 AP2A1 NAV1 RIPOR1 ZNF426	7.26e-05	1105	99	12	35748872
Pubmed	A human MAP kinase interactome.	CASP8AP2 HIVEP1 SYNE1 POM121C WNK1 ERBIN NAV1 PIBF1	7.73e-05	486	99	8	20936779
Pubmed	Characterization of functional domains in human Claspin.	POLE CLSPN	7.98e-05	5	99	2	21478680
Pubmed	DMP-1-mediated Ghr gene recombination compromises skeletal development and impairs skeletal response to intermittent PTH.	GHR DMP1	7.98e-05	5	99	2	26481310
Pubmed	Profiling of the BRCA1 transcriptome through microarray and ChIP-chip analysis.	BRCA1 AP2A1	7.98e-05	5	99	2	21880590
Pubmed	Variants in the GH-IGF axis confer susceptibility to lung cancer.	GHR AKAP9	7.98e-05	5	99	2	16741161
Pubmed	Interaction of HIV-1 Gag with the clathrin-associated adaptor AP-2.	AP2A1 AP2A2	7.98e-05	5	99	2	16139856
Pubmed	Endocytic Adaptor Proteins in Health and Disease: Lessons from Model Organisms and Human Mutations.	AP2A1 AP2A2	7.98e-05	5	99	2	31671891
Pubmed	Weak Molecular Interactions in Clathrin-Mediated Endocytosis.	AP2A1 AP2A2	7.98e-05	5	99	2	29184887
Pubmed	A conserved dileucine motif mediates clathrin and AP-2-dependent endocytosis of the HIV-1 envelope protein.	AP2A1 AP2A2	7.98e-05	5	99	2	17108326
Pubmed	Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis.	AP2A1 AP2A2	7.98e-05	5	99	2	9723620
Pubmed	Versican/PG-M is essential for ventricular septal formation subsequent to cardiac atrioventricular cushion development.	VCAN MKI67	7.98e-05	5	99	2	22692047
Pubmed	WNK regulates Wnt signalling and β-Catenin levels by interfering with the interaction between β-Catenin and GID.	RMND5A WNK1	7.98e-05	5	99	2	33184430
Pubmed	Analysis of the AP-2 adaptor complex and cargo during clathrin-mediated endocytosis.	AP2A1 AP2A2	7.98e-05	5	99	2	15941406
Pubmed	Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.	ERBIN AP2A1 AP2A2 MKI67 HNRNPR	8.16e-05	154	99	5	36490346
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	GTF3C1 BRCA1 MKI67 HFM1 POLQ HNRNPR	8.33e-05	250	99	6	33536335
Pubmed	A protein interaction landscape of breast cancer.	TRIP11 ERBIN MDN1 BRCA1 AP2A1 AP2A2 MKI67 WDR1 HNRNPR	8.47e-05	634	99	9	34591612
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	HIVEP1 POLE MUC16 POM121C TRIP11 MDN1 ASXL3 HFM1 UTY	8.88e-05	638	99	9	31182584
Pubmed	Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.	POLE BRCA1 MKI67 CLSPN POLQ	8.94e-05	157	99	5	30686591
Pubmed	Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.	WNK1 URGCP MYO3A GPR156	1.00e-04	84	99	4	15203218
Pubmed	Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk.	POLE BRCA1 POLI POLQ	1.00e-04	84	99	4	19237606
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	SYNE1 PCLO POM121C MDN1 AKAP9 AP2A1 AP2A2 MTHFD1 WDR1 SPAG17	1.04e-04	807	99	10	30575818
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	TCF7L2 HIVEP1 ZNF280D ZNF429 ZNF208 MLLT10 ZC3H6 ZBTB24 UTY ZNF426	1.05e-04	808	99	10	20412781
Pubmed	Numb expression and asymmetric versus symmetric cell division in distal embryonic lung epithelium.	AP2A1 AP2A2	1.19e-04	6	99	2	22713487
Pubmed	Rab11-FIP2, an adaptor protein connecting cellular components involved in internalization and recycling of epidermal growth factor receptors.	RAB11FIP1 AP2A1	1.19e-04	6	99	2	12364336
Pubmed	The Proliferating Cell Nuclear Antigen (PCNA)-interacting Protein (PIP) Motif of DNA Polymerase η Mediates Its Interaction with the C-terminal Domain of Rev1.	POLE POLI	1.19e-04	6	99	2	26903512
Pubmed	Clathrin.	AP2A1 AP2A2	1.19e-04	6	99	2	10966473
Pubmed	CHIP inhibits odontoblast differentiation through promoting DLX3 polyubiquitylation and degradation.	MKI67 DMP1	1.19e-04	6	99	2	37213079
Pubmed	HIV-1 Tat enters T cells using coated pits before translocating from acidified endosomes and eliciting biological responses.	AP2A1 AP2A2	1.19e-04	6	99	2	15020715
Pubmed	Molecular divergence of mammalian astrocyte progenitor cells at early gliogenesis.	MKI67 SPARCL1	1.19e-04	6	99	2	35253855
Pubmed	Calcyon, a mammalian specific NEEP21 family member, interacts with adaptor protein complex 3 (AP-3) and regulates targeting of AP-3 cargoes.	AP2A1 AP2A2	1.19e-04	6	99	2	22650988
Pubmed	Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures.	TCF7L2 MKI67	1.19e-04	6	99	2	11731231
Pubmed	The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppØ sorting signals at distinct sites.	AP2A1 AP2A2	1.19e-04	6	99	2	12121421
Pubmed	Molecular architecture and functional model of the endocytic AP2 complex.	AP2A1 AP2A2	1.19e-04	6	99	2	12086608
Pubmed	USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110.	CEP97 USP33	1.19e-04	6	99	2	23486064
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	POLE PPIL4 DOCK10 ERBIN WDR59 MDN1 GTF3C1 AP2A1 AP2A2 MTHFD1 MKI67 WDR1 HNRNPR	1.22e-04	1353	99	13	29467282
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	SYNE1 MUC16 CMYA5 MYO3A AP2A1 AP2A2 MTHFD1 UGP2 MKI67 HNRNPR	1.50e-04	844	99	10	25963833
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	POLE MECOM MDN1 AP2A1 AP2A2 MKI67 HNRNPR	1.52e-04	400	99	7	35013556
Pubmed	Clathrin interacts specifically with amphiphysin and is displaced by dynamin.	AP2A1 AP2A2	1.67e-04	7	99	2	9280305
Pubmed	Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein.	AP2A1 AP2A2	1.67e-04	7	99	2	7671305
Interaction	PFN1 interactions	RAPGEF6 PCLO CEP192 MLLT10 WNK1 TRIP11 AKAP9 BRCA1 KIAA1217 NAV1 BOD1L1 CEP97	3.85e-06	509	93	12	int:PFN1
Interaction	AP2B1 interactions	CEP192 WNK1 TRIP11 AKAP9 BRCA1 AP2A1 AP2A2 MKI67 NAV1 CEP97	8.64e-06	373	93	10	int:AP2B1
Interaction	KDM1A interactions	CASP8AP2 RAPGEF6 HIVEP1 RMND5A ZNF280D OFCC1 MECOM ZBTB24 PRDM2 CFAP100 AKAP9 GTF3C1 BRCA1 KIAA1217 NAV1	2.52e-05	941	93	15	int:KDM1A
Interaction	STIL interactions	GPATCH1 CEP192 TRIP11 AKAP9 KIAA1217 PIBF1 CEP97	2.83e-05	190	93	7	int:STIL
Interaction	FXR2 interactions	HIVEP1 MECOM TRIM29 WDR59 AKAP9 BRCA1 KIAA1217 GKAP1 MKI67 HNRNPR	2.94e-05	430	93	10	int:FXR2
Interaction	TPTE2 interactions	POLE AKAP9 BRCA1 PIBF1 USP33	4.35e-05	84	93	5	int:TPTE2
Interaction	KCTD13 interactions	IL12RB1 OXR1 SYNE1 PCLO TRIP11 ERBIN NWD2 AP2A1 AP2A2 MTHFD1 KIAA1217 VCAN GKAP1 UGP2 NAV1 WDR1 CEP97 HNRNPR	5.91e-05	1394	93	18	int:KCTD13
Cytoband	1p13.3	SLC6A17 NBPF4 NBPF6 NBPF5P SLC16A4	4.24e-07	69	99	5	1p13.3
Cytoband	6q15	CASP8AP2 MDN1 DOP1A	4.18e-05	31	99	3	6q15
Cytoband	Ensembl 112 genes in cytogenetic band chr1p13	SLC6A17 NBPF4 NBPF6 NBPF5P SLC16A4	9.85e-05	211	99	5	chr1p13
Cytoband	Xp11.22	CENPVL2 CENPVL3 CENPVL1	2.23e-04	54	99	3	Xp11.22
Cytoband	3q13.33	GPR156 POLQ	1.93e-03	30	99	2	3q13.33
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF429 ZNF208 ZNF90	2.38e-03	122	99	3	chr19p12
Cytoband	15q21.3	ZNF280D UNC13C	2.61e-03	35	99	2	15q21.3
Cytoband	7p13	URGCP CCM2	3.24e-03	39	99	2	7p13
Cytoband	Ensembl 112 genes in cytogenetic band chr10p12	MLLT10 MYO3A KIAA1217	3.52e-03	140	99	3	chr10p12
Cytoband	19p13.1	IL12RB1 ZNF429	4.87e-03	48	99	2	19p13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr6q15	CASP8AP2 MDN1	5.48e-03	51	99	2	chr6q15
Cytoband	Ensembl 112 genes in cytogenetic band chr7p13	URGCP CCM2	5.91e-03	53	99	2	chr7p13
Cytoband	Ensembl 112 genes in cytogenetic band chr3q12	CEP97 FILIP1L	6.12e-03	54	99	2	chr3q12
Cytoband	Ensembl 112 genes in cytogenetic band chr15q21	ZNF280D SPG11 UNC13C	6.74e-03	177	99	3	chr15q21
GeneFamily	DNA polymerases	POLE POLI POLQ	5.58e-05	23	59	3	535
GeneFamily	Neuroblastoma breakpoint family	NBPF4 NBPF6 NBPF5P	5.58e-05	23	59	3	662
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	HIVEP1 TSHZ2 ZNF429 MECOM ZNF208 ZNF510 ZBTB24 ZNF117 ZNF90 ZNF426	9.88e-05	718	59	10	28
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	CEP192 WNK1 AKAP9 BRCA1 MKI67	3.08e-04	181	59	5	694
GeneFamily	Endogenous ligands\|Minor histocompatibility antigens	WNK1 MTHFD1 UTY	6.15e-04	51	59	3	870
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	MECOM PRDM2	1.38e-03	17	59	2	1197
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	CMYA5 AKAP9	4.02e-03	29	59	2	396
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	MECOM PRDM2	5.49e-03	34	59	2	487
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PCLO RAB11FIP1	6.14e-03	36	59	2	823
GeneFamily	PDZ domain containing	RAPGEF6 PCLO ERBIN	1.34e-02	152	59	3	1220
GeneFamily	Fibronectin type III domain containing	IL12RB1 CMYA5 GHR	1.54e-02	160	59	3	555
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	CASP8AP2 RAPGEF6 PPIL4 DOCK10 SPG11 CEP192 TRIP11 ZNF117 BRCA1 GKAP1 MKI67 PIBF1 POLQ	8.07e-07	656	96	13	M18979
Coexpression	GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_DN	PPIL4 DOCK10 ERBIN BOD1L1 USP33 HNRNPR	3.41e-05	166	96	6	M8129
Coexpression	PGF_UP.V1_UP	TRIP11 ZNF117 AKAP9 RASGRP3 VCAN UGP2	7.23e-05	190	96	6	M2674
Coexpression	GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_UP	SYNE1 RAB11FIP1 ZC3H6 ZNF117 AP2A2 DOP1A	8.83e-05	197	96	6	M3136
Coexpression	GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_UP	MUC16 ZNF208 MKI67 CLSPN POLQ CEP97	9.08e-05	198	96	6	M8041
Coexpression	GABRIELY_MIR21_TARGETS	RMND5A DOCK10 SPG11 WNK1 RASGRP3 CEP97 FILIP1L	9.51e-05	289	96	7	M2196
Coexpression	GSE14308_TH1_VS_NAIVE_CD4_TCELL_DN	CMYA5 CCM2 AKAP9 ASXL3 KIAA1217 ADIPOR2	9.60e-05	200	96	6	M3377
Coexpression	GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_UP	HIVEP1 GCFC2 ZNF280D WNK1 ERBIN ASXL3	9.60e-05	200	96	6	M7776
Coexpression	GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_UP	RAPGEF6 DOCK10 MLLT10 NAV1 DOP1A FILIP1L	9.60e-05	200	96	6	M6447
Coexpression	GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_UP	RAPGEF6 SLC16A4 GKAP1 RIPOR1 BOD1L1 CEP97	9.60e-05	200	96	6	M8050
Coexpression	GSE27786_LSK_VS_ERYTHROBLAST_UP	RMND5B ZBTB24 URGCP PRDM2 MTHFD1 PIBF1	9.60e-05	200	96	6	M4757
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500	CASP8AP2 ZNF280D TSHZ2 PPIL4 DOCK10 MECOM CEP192 AKAP9 ASXL3 MKI67 NAV1 BOD1L1 CLSPN PIBF1 FILIP1L	4.86e-09	492	95	15	Facebase_RNAseq_e10.5_Mandibular Arch_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5	CASP8AP2 ZNF280D PPIL4 CEP192 AKAP9 MKI67 NAV1 BOD1L1 CLSPN PIBF1	1.11e-08	186	95	10	Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	CASP8AP2 TCF7L2 ZNF280D MECOM AKAP9 BRCA1 SLC16A4 MKI67 BOD1L1 CLSPN PIBF1 POLQ	1.46e-08	311	95	12	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	CASP8AP2 TCF7L2 GCFC2 PCLO AKAP9 BRCA1 SLC16A4 GKAP1 MKI67 BOD1L1 CLSPN PIBF1 POLQ ZNF426 ADIPOR2	4.06e-06	831	95	15	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	CASP8AP2 TCF7L2 ZNF280D PCLO MECOM AKAP9 BRCA1 SLC16A4 GKAP1 MKI67 BOD1L1 CLSPN PIBF1 POLQ CEP97 ADIPOR2	7.52e-06	989	95	16	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3	CASP8AP2 AKAP9 BRCA1 GKAP1 CLSPN PIBF1 POLQ	2.50e-05	192	95	7	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000	CASP8AP2 ZNF280D TSHZ2 PPIL4 DOCK10 MECOM CEP192 AKAP9 ASXL3 MKI67 NAV1 BOD1L1 CLSPN PIBF1 FILIP1L	2.80e-05	978	95	15	Facebase_RNAseq_e10.5_Mandibular Arch_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	ZNF280D PCLO PPIL4 WNK1 PRDM2 GTF3C1 SLC16A4 MKI67 BOD1L1 CLSPN ADIPOR2	7.08e-05	595	95	11	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	CASP8AP2 HIVEP1 TSHZ2 DOCK10 MUC16 GHR ASXL3 KIAA1217 RASGRP3 VCAN SPARCL1 CLSPN UTY	7.89e-05	827	95	13	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#3	ZNF280D TSHZ2 SYNE1 DOCK10 MECOM CEP192 ASXL3 MKI67 BOD1L1 CLSPN PIBF1 DOP1A FILIP1L	8.58e-05	834	95	13	Facebase_RNAseq_e10.5_Mandibular Arch_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#5	ZNF280D TSHZ2 DOCK10 CEP192 ASXL3 MKI67 BOD1L1 FILIP1L	1.20e-04	331	95	8	Facebase_RNAseq_e10.5_Mandibular Arch_1000_K5
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000	TSHZ2 MUC16 WNK1 GHR ASXL3 VCAN SPARCL1	1.89e-04	265	95	7	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4	ZNF280D PCLO AKAP9 BRCA1 MKI67 CLSPN	2.25e-04	192	95	6	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500	CASP8AP2 POLE ZC3H6 MDN1 BRCA1 GKAP1 HFM1 CLSPN	3.34e-04	385	95	8	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500	ZNF280D PCLO DOCK10 AKAP9 BRCA1 ASXL3 MKI67 CLSPN FILIP1L	3.60e-04	492	95	9	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	CASP8AP2 TCF7L2 PCLO AKAP9 BRCA1 CLSPN PIBF1	3.85e-04	298	95	7	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K4
CoexpressionAtlas	facebase_RNAseq_e10.5_MandArch_2500_K1	CASP8AP2 ZNF280D POLE CEP192 ERBIN MDN1 AKAP9 BRCA1 ASXL3 VCAN MKI67 BOD1L1 CLSPN PIBF1 FILIP1L	3.91e-04	1241	95	15	facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlas	dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#1_top-relative-expression-ranked_500	KIAA1217 VCAN NAV1	3.92e-04	32	95	3	gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k1_500
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000	TSHZ2 DOCK10 MUC16 GHR BRCA1 SLC16A4 ASXL3 KIAA1217 VCAN SPARCL1 UTY FILIP1L	4.01e-04	849	95	12	gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#2	PCLO MECOM AKAP9 CLSPN	4.37e-04	79	95	4	Facebase_RNAseq_e10.5_Maxillary Arch_500_K2
ToppCell	PBMC-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	POLE MECOM BRCA1 MTHFD1 MKI67 CLSPN POLQ	2.22e-07	189	99	7	946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CASP8AP2 POLE BRCA1 MTHFD1 ZNF90 CLSPN POLQ	2.74e-07	195	99	7	b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CASP8AP2 POLE BRCA1 MTHFD1 ZNF90 CLSPN POLQ	2.74e-07	195	99	7	56d8734d020b3da08a5aa9e67999706a9e023a99
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TSHZ2 DOCK10 GHR ASXL3 VCAN UNC13C SPARCL1	2.94e-07	197	99	7	11a4c417f035e554431a8f03be13b5eefa3530c0
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TSHZ2 MUC16 MECOM RAB11FIP1 TRIM29 AKAP9 KIAA1217	3.25e-07	200	99	7	64462a18afca3c1a8548a857924b8166058bf958
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TSHZ2 PCLO MUC16 TRIM29 AKAP9 KIAA1217 SPARCL1	3.25e-07	200	99	7	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	POLE MYO3A BRCA1 MKI67 CLSPN POLQ	2.16e-06	169	99	6	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	POLE MYO3A BRCA1 MKI67 CLSPN POLQ	2.16e-06	169	99	6	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	POLE MYO3A BRCA1 MKI67 CLSPN POLQ	2.55e-06	174	99	6	84da9faff088d05233183b425385beb054c92d1b
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	POLE BRCA1 VCAN MKI67 CLSPN POLQ	3.01e-06	179	99	6	e1bfd553c043ebc070ccf8545d489ba16d9b2ef4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CASP8AP2 MYO3A BRCA1 MKI67 CLSPN POLQ	3.01e-06	179	99	6	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 PCLO ASXL3 UNC13C SPAG17 UNC80	3.52e-06	184	99	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 PCLO ASXL3 UNC13C SPAG17 UNC80	3.52e-06	184	99	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 PCLO ASXL3 UNC13C SPAG17 UNC80	3.52e-06	184	99	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	POLE CEP192 BRCA1 SLC16A4 CLSPN POLQ	4.24e-06	190	99	6	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	POLE CEP192 BRCA1 MKI67 CLSPN POLQ	4.64e-06	193	99	6	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RMND5A ZNF280D RIPOR1 XRRA1 UTY CEP97	4.64e-06	193	99	6	a6a864644e1b80b7417ea0a27281e79068a3fd3d
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	HIVEP1 WNK1 ERBIN WDR59 AKAP9 VCAN	4.64e-06	193	99	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7L2 TRIM29 BRCA1 MKI67 CLSPN ADIPOR2	4.78e-06	194	99	6	effd38e51062b225ecabc7e1c50154e65495d559
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	POLE BRCA1 MTHFD1 MKI67 CLSPN POLQ	4.78e-06	194	99	6	4c1d13d8cb6fb424655c67755ee6dbaf59d6b418
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TSHZ2 DOCK10 GHR VCAN UNC13C SPARCL1	4.78e-06	194	99	6	a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CASP8AP2 POLE BRCA1 MTHFD1 CLSPN POLQ	4.92e-06	195	99	6	cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TSHZ2 DOCK10 GHR VCAN UNC13C SPARCL1	4.92e-06	195	99	6	1cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCell	Control-Lymphoid-Proliferating_CD4_T_cells\|Lymphoid / Condition, Lineage and Cell class	TCF7L2 BRCA1 VCAN MKI67 CLSPN POLQ	4.92e-06	195	99	6	578bbb06a5476c08fc3b351cc580c551dfe53ae4
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO TRIP11 AKAP9 BOD1L1 UTY UNC80	4.92e-06	195	99	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CASP8AP2 POLE BRCA1 MTHFD1 CLSPN POLQ	5.07e-06	196	99	6	df366d76ea55f49e349d622effa57c1535df8400
ToppCell	PCW_13-14-Mesenchymal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TSHZ2 DOCK10 GHR VCAN UNC13C SPARCL1	5.22e-06	197	99	6	73a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCell	Sigmoid-T_cell-Treg\|T_cell / Region, Cell class and subclass	RMND5B TSHZ2 ZBTB24 CCM2 AP2A2 UGP2	5.37e-06	198	99	6	e2d2f9f209f77d0c48cfe3e9902c0ae0795511b2
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYNE1 TRDC BRCA1 MKI67 CLSPN POLQ	5.37e-06	198	99	6	80b105a7c7d00ea3b5e586831fbb755bd84f9d1a
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 TRDC BRCA1 MKI67 CLSPN POLQ	5.37e-06	198	99	6	c73e906d2d12d6eba0e606958be16e63a2292cd0
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	POLE MYO3A BRCA1 MKI67 CLSPN POLQ	5.37e-06	198	99	6	d5e125f0c4f41b47d567568d0838adcca7655f6d
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	TRDC BRCA1 MTHFD1 MKI67 CLSPN POLQ	5.53e-06	199	99	6	305a9ade5bbe8e981e7c641c9a5e0c9f8ef60470
ToppCell	Biopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	POLE MYO3A BRCA1 MKI67 CLSPN POLQ	5.53e-06	199	99	6	4fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYNE1 TRDC BRCA1 MKI67 CLSPN POLQ	5.53e-06	199	99	6	101f78fe6dd1bf9e2e4dd5ad8a970312b3540927
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 TRDC BRCA1 MKI67 CLSPN POLQ	5.53e-06	199	99	6	e0fcec796afe75e42467ca86355b9fc5aa9ae0a1
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SYNE1 CMYA5 KIAA1217 VCAN NAV1 UNC80	5.53e-06	199	99	6	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRDC BRCA1 MTHFD1 MKI67 CLSPN POLQ	5.53e-06	199	99	6	fba48342066aab41a8bcb20db40a6df0158e1cbe
ToppCell	356C-Lymphocytic-NK_cells-Proliferating_NK_cell\|356C / Donor, Lineage, Cell class and subclass (all cells)	TRDC BRCA1 MTHFD1 MKI67 CLSPN POLQ	5.53e-06	199	99	6	e3b69608c834bd8ce6bedde298a2763cc0d7d573
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TSHZ2 PCLO TRIM29 AKAP9 KIAA1217 SPARCL1	5.69e-06	200	99	6	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	SYNE1 GHR VCAN SPARCL1 DMP1 FILIP1L	5.69e-06	200	99	6	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TSHZ2 SYNE1 GHR SPARCL1 DMP1 FILIP1L	5.69e-06	200	99	6	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	POLE MYO3A BRCA1 MKI67 CLSPN POLQ	5.69e-06	200	99	6	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CASP8AP2 SLC6A17 BRCA1 CLSPN POLQ	1.48e-05	139	99	5	c9bf98bed77415a1438f3f9e441a1346e75c26b0
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CMYA5 VCAN NAV1 HFM1 CEP97	2.51e-05	155	99	5	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	PND07-28-samps-Myeloid-Macrophage-macrophage-B\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TCF7L2 FXYD5 DOCK10 TRIM29 ADIPOR2	2.92e-05	160	99	5	694bf1f1952bd8ab444819f533da24fa2b73f701
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CASP8AP2 MLLT10 MKI67 CLSPN CEP97	3.28e-05	164	99	5	5621c2e3fae84d5a2e4f1595e454bcb3a2b3f93c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO3A BRCA1 MKI67 CLSPN POLQ	3.38e-05	165	99	5	88681101d7cf60b99b8ace5d8c0944323b937306
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO3A BRCA1 MKI67 CLSPN POLQ	3.58e-05	167	99	5	50c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO3A BRCA1 MKI67 CLSPN POLQ	3.68e-05	168	99	5	d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CASP8AP2 POLE BRCA1 CLSPN POLQ	3.79e-05	169	99	5	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ2 VCAN MKI67 CLSPN POLQ	4.01e-05	171	99	5	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 POLE MKI67 CLSPN POLQ	4.01e-05	171	99	5	1eebd7138c3b20ddc1104f21615f9df0e776bbe6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ2 VCAN MKI67 CLSPN POLQ	4.01e-05	171	99	5	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF7L2 DOCK10 TRIM29 MKI67 ADIPOR2	4.72e-05	177	99	5	67cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 SYNE1 TRIP11 AKAP9 FILIP1L	4.85e-05	178	99	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 POLE BRCA1 MKI67 CLSPN	4.85e-05	178	99	5	79823d13652177de852c2acce9159049241f1d86
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 TSHZ2 MECOM NAV1 UTY	4.98e-05	179	99	5	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSHZ2 MUC16 CMYA5 RAB11FIP1 KIAA1217	4.98e-05	179	99	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	LA-01._Fibroblast_I\|LA / Chamber and Cluster_Paper	TSHZ2 MECOM VCAN NAV1 SPARCL1	4.98e-05	179	99	5	dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO3A BRCA1 MKI67 CLSPN POLQ	5.12e-05	180	99	5	f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 TSHZ2 GHR VCAN SPARCL1	5.25e-05	181	99	5	35eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 TSHZ2 GHR VCAN SPARCL1	5.25e-05	181	99	5	e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|bone_marrow / Manually curated celltypes from each tissue	BRCA1 VCAN MKI67 CLSPN POLQ	5.25e-05	181	99	5	ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 POLE BRCA1 MKI67 CLSPN	5.39e-05	182	99	5	0370b395ceb9d4d66f80cf60dd8c28ac60af5c7b
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM29 MKI67 DMP1 CLSPN POLQ	5.39e-05	182	99	5	39f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TSHZ2 MECOM NAV1 SPARCL1 FILIP1L	5.39e-05	182	99	5	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	COVID-19_Mild-gd_T\|COVID-19_Mild / Disease condition and Cell class	TCF7L2 SYNE1 ERBIN TRDC GTF3C1	5.53e-05	183	99	5	f593a89b0aa8fffdfa403769916facfd30358521
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF280D CMYA5 HFM1 SPARCL1 FILIP1L	5.53e-05	183	99	5	269afec240a756eec3bbae5f30ec784281af3433
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL12RB1 POLE BRCA1 MKI67 CLSPN	5.68e-05	184	99	5	1edefa2a049d7e22d0bdb1ea3d7ef1c8d6ae0fe3
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-Proliferating_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL12RB1 POLE BRCA1 MKI67 CLSPN	5.68e-05	184	99	5	8578c50eaa8ce1cefc0228185c66c8e25f4bfc32
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF7L2 PCLO MKI67 CLSPN POLQ	5.68e-05	184	99	5	16aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCF7L2 PCLO TRIM29 MKI67 CLSPN	5.82e-05	185	99	5	b4af9ae4c358b48357cb135b740266e1652d886a
ToppCell	facs-Thymus-Flowthrough-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RMND5A ZNF280D IP6K1 XRRA1 CEP97	5.82e-05	185	99	5	dc59b8dc459a3c444c9634a0d438cbef54c40036
ToppCell	Control-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	RAPGEF6 HIVEP1 TSHZ2 RAB11FIP1 UGP2	5.82e-05	185	99	5	e481cacda0b6b25f5f0062b962df9a442053ac30
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO3A BRCA1 MKI67 CLSPN POLQ	5.82e-05	185	99	5	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP1 TRIM29 WNK1 ERBIN UTY	5.82e-05	185	99	5	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	BRCA1 MKI67 HFM1 CLSPN POLQ	5.82e-05	185	99	5	9d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PCLO MUC16 VCAN NAV1 SPAG17	5.98e-05	186	99	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|bone_marrow / Manually curated celltypes from each tissue	BRCA1 VCAN MKI67 CLSPN POLQ	5.98e-05	186	99	5	e82d5e7a976b9cfa2b4640c7a7cd1cfea19c4806
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ2 BRCA1 MKI67 CLSPN POLQ	6.13e-05	187	99	5	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ2 BRCA1 MKI67 CLSPN POLQ	6.13e-05	187	99	5	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO3A BRCA1 MKI67 CLSPN POLQ	6.13e-05	187	99	5	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA1 MKI67 UNC13C CLSPN POLQ	6.13e-05	187	99	5	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	droplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL12RB1 POLE MKI67 CLSPN POLQ	6.29e-05	188	99	5	0ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCell	E12.5-Mesenchymal\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TSHZ2 GHR VCAN UGP2 SPARCL1	6.29e-05	188	99	5	9778dadc2bd7ded3a723e717d1c8cd3160e99c6c
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POLE BRCA1 MKI67 CLSPN POLQ	6.29e-05	188	99	5	61ae7405ab56570409bf35382dc0a038e4137c15
ToppCell	facs-Thymus-Flowthrough-3m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RMND5A ZNF280D IP6K1 XRRA1 CEP97	6.29e-05	188	99	5	59b71462338a7efbacf46577cb07e9db3363afee
ToppCell	COVID-19-Heart-EC_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SYNE1 MECOM KIAA1217 RASGRP3 SPARCL1	6.44e-05	189	99	5	fe49852ba15f948b384d6b4c258927c70b741357
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	OXR1 SYNE1 MECOM KIAA1217 UTY	6.44e-05	189	99	5	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	POLE BRCA1 MKI67 CLSPN POLQ	6.44e-05	189	99	5	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	droplet-Marrow-nan-3m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 BRCA1 MKI67 CLSPN POLQ	6.44e-05	189	99	5	8a38baee58a27c2fa3f4bd131ab9f15723ed9295
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA1 MKI67 NAV1 CLSPN POLQ	6.61e-05	190	99	5	31de1727822e9818652946dfb962daee77ffad68
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	SYNE1 KIAA1217 NAV1 SPARCL1 ADIPOR2	6.61e-05	190	99	5	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TCF7L2 TSHZ2 GHR VCAN SPARCL1	6.61e-05	190	99	5	7986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	OXR1 SYNE1 MECOM DNAH14 SPAG17	6.61e-05	190	99	5	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRDC BRCA1 MKI67 CLSPN POLQ	6.61e-05	190	99	5	c3c65d1f24e0ebdbb9adb617bed299a668f423f5
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	POLE BRCA1 MKI67 CLSPN POLQ	6.77e-05	191	99	5	15dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCell	COPD-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	RAPGEF6 HIVEP1 TSHZ2 RAB11FIP1 UGP2	6.77e-05	191	99	5	3ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCell	Control-Epithelial-Ciliated_cells\|Control / Condition, Lineage and Cell class	MUC16 MECOM TRIM29 CFAP100 SPAG17	6.77e-05	191	99	5	ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	POLE BRCA1 MKI67 CLSPN POLQ	6.77e-05	191	99	5	45c15f5ce4a207ac944bed65d45f06c1657d1a6d
Drug	Succimer	CASP8AP2 HIVEP1 RMND5A ZNF280D DOCK10 MECOM MLLT10 TRIM29 TRIP11 PRDM2 ZNF117 AKAP9 BRCA1 SLC16A4 RASGRP3 MKI67 NAV1 CLSPN UTY	8.19e-07	1264	94	19	ctd:D004113
Drug	Magnetite Nanoparticles	CASP8AP2 HIVEP1 RMND5A ZNF280D DOCK10 MECOM MLLT10 TRIM29 TRIP11 PRDM2 ZNF117 AKAP9 BRCA1 SLC16A4 RASGRP3 MKI67 NAV1 CLSPN UTY	1.40e-06	1310	94	19	ctd:D058185
Drug	Prochlorperazine dimaleate [84-02-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A	MLLT10 WNK1 TRIP11 AP2A2 PIBF1 CEP97 DOP1A FILIP1L	1.61e-06	197	94	8	2641_DN
Drug	petasiphenol	POLE BRCA1 POLI POLQ	1.88e-06	22	94	4	CID006438779
Drug	diethyl acetylenedicarboxylate	SYNE1 SPAG17	1.69e-05	2	94	2	CID000069803
Drug	Acetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; HL60; HG-U133A	TCF7L2 ZNF280D SPG11 GTF3C1 BRCA1 WDR1 ZNF426	1.83e-05	198	94	7	1377_UP
Drug	Oxantel pamoate [68813-55-8]; Up 200; 6.6uM; HL60; HT_HG-U133A	TCF7L2 RMND5A MLLT10 TRIP11 WDR59 AKAP9 WDR1	1.89e-05	199	94	7	1277_UP
Drug	9-aminoacridine	SYNE1 POLE WNK1 POLI POLQ	1.91e-05	79	94	5	CID000007019
Disease	neuroticism measurement, cognitive function measurement	TCF7L2 HIVEP1 PCLO MLLT10 GTF3C1 ASXL3 KIAA1217 GKAP1 NAV1 USP33	1.33e-05	566	94	10	EFO_0007660, EFO_0008354
Disease	MENTAL RETARDATION, AUTOSOMAL DOMINANT 40	BRCA1 HNRNPR	3.56e-04	9	94	2	C4225275
Disease	ovarian carcinoma	MECOM MLLT10 BRCA1 MTHFD1 ASXL3 SPATS1	5.77e-04	321	94	6	EFO_0001075
Disease	colorectal cancer (is_implicated_in)	TCF7L2 POLE BRCA1 MKI67	6.17e-04	121	94	4	DOID:9256 (is_implicated_in)
Disease	Malignant neoplasm of breast	SYNE1 MECOM TRIM29 WNK1 AKAP9 BRCA1 MKI67 BOD1L1 CLSPN DOP1A HNRNPR	6.18e-04	1074	94	11	C0006142
Disease	body weight	TCF7L2 HIVEP1 MECOM CEP192 MLLT10 POM121C WDR59 DNAH14 GHR ASXL3 KIAA1217 DMP1	6.63e-04	1261	94	12	EFO_0004338
Disease	peak insulin response measurement	TCF7L2 URGCP	7.65e-04	13	94	2	EFO_0008000
Disease	Global developmental delay	OXR1 UGP2 PIBF1 HNRNPR	8.79e-04	133	94	4	C0557874
Disease	ovarian neoplasm	MUC16 MECOM BRCA1 MKI67	9.04e-04	134	94	4	C0919267
Disease	Malignant neoplasm of ovary	MUC16 MECOM BRCA1 MKI67	9.82e-04	137	94	4	C1140680
Disease	cholangiocarcinoma (is_marker_for)	MUC16 MKI67 OSBP2	1.13e-03	64	94	3	DOID:4947 (is_marker_for)
Disease	Prostate cancer, familial	TCF7L2 MECOM BRCA1	1.41e-03	69	94	3	C2931456
Disease	unipolar depression, bipolar disorder	TCF7L2 SYNE1 PCLO ASXL3	1.58e-03	156	94	4	EFO_0003761, MONDO_0004985
Disease	Joubert syndrome 1	KATNIP PIBF1	2.03e-03	21	94	2	C4551568
Disease	urate measurement	TCF7L2 POLE MECOM TRIM29 NAV1 HFM1 SPARCL1 WDR1 DMP1	2.23e-03	895	94	9	EFO_0004531
Disease	neuroimaging measurement, brain volume measurement	TCF7L2 GPATCH1 MLLT10 RASGRP3 VCAN	2.25e-03	286	94	5	EFO_0004346, EFO_0006930
Disease	post-traumatic stress disorder symptom measurement	TCF7L2 SYNE1 IP6K1	2.31e-03	82	94	3	EFO_0008535
Disease	urinary albumin to creatinine ratio	TCF7L2 MLLT10 TRIM29 UNC13C	2.61e-03	179	94	4	EFO_0007778
Disease	eosinophil count	RAPGEF6 HIVEP1 ZNF429 WNK1 WDR59 CCM2 MDN1 AKAP9 BRCA1 GKAP1 POLI HFM1	2.69e-03	1488	94	12	EFO_0004842
Disease	corpus collosum mid-posterior volume measurement	UGP2 UNC13C	2.87e-03	25	94	2	EFO_0010300
Disease	Intellectual Disability	OXR1 SYNE1 ZBTB24 BRCA1 UGP2 HNRNPR	3.10e-03	447	94	6	C3714756
Disease	Uterine leiomyoma	SYNE1 ZNF208 MLLT10	3.11e-03	91	94	3	HP_0000131

Protein segments in the cluster

Peptide	Gene	Start	Entry
SDVETHFRTSHENTK	ZNF280D	431	Q6N043
KSVDSTATADDTHKL	ERBIN	746	Q96RT1
KTSSSKHDVSAHHDL	AKAP9	41	Q99996
TVSKTSEDTIHTHLE	VCAN	581	P13611
HTHLEDLESVSASTT	VCAN	591	P13611
LASSEFSHEAVKTHI	AP2A1	356	O95782
HTLHDSSVASIETKS	DOP1A	1246	Q5JWR5
SEDHISKKTEELSSS	GKAP1	186	Q5VSY0
THHLSLHSDDSSTKV	CCM2	241	Q9BSQ5
LHSDDSSTKVDIKET	CCM2	246	Q9BSQ5
EEAAEEHKAIHKTSS	CENPVL1	246	A0A0U1RR11
THKSTKAAHPTDDTT	FXYD5	91	Q96DB9
AKSDVSKDVHHSTSL	CASP8AP2	181	Q9UKL3
STSSMTHVSDTEHKE	ASXL3	546	Q9C0F0
THVSDTEHKESETAV	ASXL3	551	Q9C0F0
ASSEFSHEAVKTHIE	AP2A2	356	O94973
HKDVDESSLSVTVHE	NWD2	626	Q9ULI1
HRSTKITFKEHEVDS	NBPF4	226	Q96M43
LEASVLSSHHKKSSE	ADIPOR2	46	Q86V24
ILDEQAEDSKSSHSH	PPIL4	366	Q8WUA2
AEDSKSSHSHTSKKH	PPIL4	371	Q8WUA2
DKESLHSTSHSSSNV	MECOM	1196	Q03112
EETNTHHSTSGKETE	MUC16	416	Q8WXI7
RDTKAIHHSADTAVT	MUC16	4236	Q8WXI7
KHDEASSLSHPDLTS	MDN1	2906	Q9NU22
KAIHSDFSRSASHTE	KATNIP	86	O60303
SHSTLSSRFTHAKEE	GPATCH1	561	Q9BRR8
KEQTESIDHGKSHSS	PCLO	4826	Q9Y6V0
TSSVTHTEHYKTLIE	HNRNPR	21	O43390
TSSIHSKETFHSLTI	POLE	1891	Q07864
KLTQTSGETTHTHTE	MKI67	1651	P46013
EDSSHTLSHSKSESR	DMP1	386	Q13316
DEATTPADKSELHHT	OSBP2	291	Q969R2
KIREEELCHHSSSST	POM121C	431	A8CG34
HHSSSSTPLAADKES	POM121B	46	A6NF01
ETQISHSKHSDISTI	HFM1	1111	A2PYH4
KSHEIHKEASEATTA	OFCC1	156	Q8IZS5
KHKITSADGHIESSA	OXR1	531	Q8N573
QEHHLSEETKCSASL	BRCA1	1281	P38398
SNSEKHADHRSTLTK	BOD1L1	1191	Q8NFC6
HEDADKDEDTTSHSS	DOCK10	156	Q96BY6
EEAAEEHKAIHKTSS	CENPVL2	246	P0DPI3
STDEEDKIHHSSESK	GCFC2	96	P16383
DTDRLLSSDHEKSHS	GHR	361	P10912
SSSVITTEDNKIHIH	FILIP1L	1051	Q4L180
VHSLQHSLDFEKSST	CEP97	711	Q8IW35
LTHSESEVKEHTFIS	POLQ	911	O75417
HTVHTIQTSKDDTSD	CMYA5	2846	Q8N3K9
EEAAEEHKAIHKTSS	CENPVL3	246	A0A0U1RRI6
TEKTLEELSHTLKHT	CFAP100	411	Q494V2
FTHHVISNTTDKDEK	DNAH14	3356	Q0VDD8
HVSVKNHSLDSVSVD	IL12RB1	451	P42701
SLISLDSHSSETTHK	CEP192	281	Q8TEP8
DSHSSETTHKESEES	CEP192	286	Q8TEP8
HKEEKASLSLETSES	IP6K1	131	Q92551
DLCKTTITSSHHSSK	GPR156	26	Q8NFN8
SHKQTVATDSHEGLT	POLI	676	Q9UNA4
TVTTCHSKTAHLDEE	MTHFD1	191	P11586
SVLDLSVHKKHCSDS	PRDM2	846	Q13029
DTTHASKVPDLHATS	NAV1	816	Q8NEY1
RTQHKDHSDNESTSS	UTY	1001	O14607
SDTHHTSTAESQKKA	RAB11FIP1	1116	Q6WKZ4
EHKNHSTVTVEEAKA	TRIM29	251	Q14134
TVQKLASDHKDIHSS	RMND5A	71	Q9H871
KKHTEDTISVASSLH	RAPGEF6	1221	Q8TEU7
KTSSSHEAEEKLSEH	SYNE1	5131	Q8NF91
HRSTKITFKEHEVDS	NBPF5P	226	Q86XG9
HRSTKITFKEHEVDS	NBPF6	226	Q5VWK0
LKETHSHLSSEVTKN	RASGRP3	256	Q8IV61
SHTRLTESSVHDFKT	KIAA1217	1321	Q5T5P2
DEHTLVTTSHDASVK	WDR1	586	O75083
EETTKSHVTEVAAHL	SPAG17	1831	Q6Q759
LSDSSSHSQDKHHEK	MLLT10	216	P55197
SSHHKEIIDTANTTE	CLSPN	341	Q9HAW4
KSSVSDQFDHLSSHL	SPG11	561	Q96JI7
DHSHVLVKVSSTDSD	URGCP	411	Q8TCY9
TTASSHEFEHTKKDL	UGP2	41	Q16851
DSDVEHTESSHKKRT	ZC3H6	86	P61129
DENEDSKDSLHSSSH	UNC80	1401	Q8N2C7
SKDSLHSSSHTLKSD	UNC80	1406	Q8N2C7
HSSSHTLKSDAGVEE	UNC80	1411	Q8N2C7
HVNALKHSIDEISSS	UNC13C	266	Q8NB66
ETHCHETEESTIKDS	SLC16A4	226	O15374
LDRKLSFSHSDHSSE	SPATS1	101	Q496A3
TVQKLASDHKDIHSS	RMND5B	71	Q96G75
TAVSTEDDSHHKAEK	SPARCL1	56	Q14515
SDVGSLHSSKHQDSK	TCF7L2	326	Q9NQB0
HSKHSENSLLLTKTE	PIBF1	696	Q8WXW3
KESPHEEASSFSHSE	TSHZ2	616	Q9NRE2
EKTLHTEDTDHQHTA	WDR59	346	Q6PJI9
IHSKEKHASDASSIS	ZBTB24	511	O43167
SNLTTHKISHTEEKL	ZNF90	466	Q03938
SSSTLSYHKKIHTEE	ZNF208	956	O43345
DTDHKETKDVLSSSL	TRIP11	786	Q15643
ISSTFTKHKIIHTEE	ZNF429	296	Q86V71
HSTDFEVKTDSTDHV	TRDC	81	B7Z8K6
QSSTLTTHKIIHTEE	ZNF117	456	Q03924
KHNSSHTGETSSKDD	ZNF510	271	Q9Y2H8
KVTQREHSSEHVTES	SLC6A17	6	Q9H1V8
TVVVSAHSLDKTSHS	WNK1	1521	Q9H4A3
LHATFEESLDKTSHS	GTF3C1	1301	Q12789
APSAHLDSVHKSTDS	RIPOR1	526	Q6ZS17
ESSFAVLHSASESHK	HIVEP1	81	P15822
SSSFRIHEKTHTEEK	ZNF426	516	Q9BUY5
TVHSEETLSHLSDTT	XRRA1	531	Q6P2D8
ESQVDHSTIHSQETK	USP33	86	Q8TEY7
EFSSVATEHQIDKSH	MYO3A	611	Q8NEV4