Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL4A3 SLIT2 COL28A1 ACAN LAMA5 LTBP2	1.57e-05	188	57	6	GO:0005201
GeneOntologyMolecularFunction	metalloendopeptidase activity	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	2.35e-05	120	57	5	GO:0004222
GeneOntologyMolecularFunction	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	GCNT3 GCNT1	2.40e-05	3	57	2	GO:0003829
GeneOntologyMolecularFunction	extracellular matrix binding	SLIT2 ZAN ADAMTS15 LTBP2	5.61e-05	73	57	4	GO:0050840
GeneOntologyMolecularFunction	metallopeptidase activity	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	2.63e-04	200	57	5	GO:0008237
GeneOntologyMolecularFunction	Roundabout binding	SLIT2 MYO9B	5.19e-04	12	57	2	GO:0048495
GeneOntologyMolecularFunction	glycosaminoglycan binding	SLIT2 COL28A1 ACAN ADAMTS15 LTBP2	9.94e-04	268	57	5	GO:0005539
GeneOntologyMolecularFunction	endopeptidase activity	ADAMTS12 ADAMTS6 PRSS56 ADAMTS16 ADAMTS15 ADAM30	1.38e-03	430	57	6	GO:0004175
GeneOntologyBiologicalProcess	kidney development	COL4A3 SLIT2 GCNT3 ADAMTS6 ADAMTS16 LAMA5 GCNT1 RET IRX2	5.61e-07	372	55	9	GO:0001822
GeneOntologyBiologicalProcess	renal system development	COL4A3 SLIT2 GCNT3 ADAMTS6 ADAMTS16 LAMA5 GCNT1 RET IRX2	7.63e-07	386	55	9	GO:0072001
GeneOntologyBiologicalProcess	extracellular matrix organization	ADAMTS12 COL4A3 ADAMTS6 COL28A1 ACAN ADAMTS16 ADAMTS15 AXIN2	6.65e-06	377	55	8	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	ADAMTS12 COL4A3 ADAMTS6 COL28A1 ACAN ADAMTS16 ADAMTS15 AXIN2	6.78e-06	378	55	8	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	ADAMTS12 COL4A3 ADAMTS6 COL28A1 ACAN ADAMTS16 ADAMTS15 AXIN2	6.91e-06	379	55	8	GO:0045229
GeneOntologyBiologicalProcess	kidney morphogenesis	GCNT3 ADAMTS16 LAMA5 GCNT1 IRX2	1.16e-05	111	55	5	GO:0060993
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	ADAMTS12 SLIT2 SHROOM3 ADAMTS16 LAMA5 RET CSMD1 IRX2	1.48e-05	421	55	8	GO:0060562
GeneOntologyBiologicalProcess	tissue morphogenesis	ADAMTS12 SLIT2 SHROOM3 GCNT3 ADAMTS16 LAMA5 GCNT1 RET CSMD1 IRX2	2.53e-05	750	55	10	GO:0048729
GeneOntologyBiologicalProcess	kidney epithelium development	SLIT2 ADAMTS16 LAMA5 RET IRX2	7.12e-05	162	55	5	GO:0072073
GeneOntologyBiologicalProcess	nephron development	COL4A3 ADAMTS16 LAMA5 RET IRX2	9.97e-05	174	55	5	GO:0072006
GeneOntologyBiologicalProcess	Roundabout signaling pathway	SLIT2 MYO9B	1.45e-04	7	55	2	GO:0035385
GeneOntologyBiologicalProcess	ureteric bud development	SLIT2 ADAMTS16 LAMA5 RET	1.90e-04	107	55	4	GO:0001657
GeneOntologyBiologicalProcess	mesonephric tubule development	SLIT2 ADAMTS16 LAMA5 RET	2.12e-04	110	55	4	GO:0072164
GeneOntologyBiologicalProcess	mesonephric epithelium development	SLIT2 ADAMTS16 LAMA5 RET	2.12e-04	110	55	4	GO:0072163
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	ADAMTS12 SLIT2 SHROOM3 ADAMTS16 LAMA5 RET CSMD1 IRX2	2.21e-04	619	55	8	GO:0002009
GeneOntologyBiologicalProcess	mesonephros development	SLIT2 ADAMTS16 LAMA5 RET	2.35e-04	113	55	4	GO:0001823
GeneOntologyBiologicalProcess	chondrocyte differentiation	ADAMTS12 ACAN LTBP3 AXIN2	4.37e-04	133	55	4	GO:0002062
GeneOntologyBiologicalProcess	cartilage development	ADAMTS12 ACAN LTBP3 CR2 AXIN2	4.69e-04	243	55	5	GO:0051216
GeneOntologyBiologicalProcess	regulation of chondrocyte differentiation	ADAMTS12 LTBP3 AXIN2	5.25e-04	59	55	3	GO:0032330
GeneOntologyCellularComponent	extracellular matrix	ADAMTS12 COL4A3 SLIT2 ZAN ADAMTS6 COL28A1 ACAN ADAMTS16 ADAMTS15 LAMA5 LTBP2 LTBP3	1.60e-07	656	57	12	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADAMTS12 COL4A3 SLIT2 ZAN ADAMTS6 COL28A1 ACAN ADAMTS16 ADAMTS15 LAMA5 LTBP2 LTBP3	1.66e-07	658	57	12	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL4A3 SLIT2 COL28A1 ACAN ADAMTS15 LAMA5 LTBP2 LTBP3	8.98e-05	530	57	8	GO:0062023
GeneOntologyCellularComponent	basement membrane	COL4A3 COL28A1 ACAN LAMA5	3.43e-04	122	57	4	GO:0005604
GeneOntologyCellularComponent	synapse-associated extracellular matrix	ACAN LAMA5	5.59e-04	13	57	2	GO:0099535
GeneOntologyCellularComponent	supramolecular polymer	COL4A3 STK11 DLGAP2 FLNC CLIP3 SHROOM3 MYO9B COL28A1 RP1L1 KIF1C	1.26e-03	1187	57	10	GO:0099081
GeneOntologyCellularComponent	complex of collagen trimers	COL4A3 COL28A1	1.48e-03	21	57	2	GO:0098644
MousePheno	abnormal ureteric bud morphology	SLIT2 LAMA5 RET GEN1	4.23e-05	57	48	4	MP:0006032
MousePheno	abnormal placenta vasculature	SLIT2 STK11 ADAMTS6 LAMA5 KIRREL1 ATP11A	4.72e-05	192	48	6	MP:0003231
MousePheno	protruding tongue	SHROOM3 ACAN AXIN2	5.59e-05	22	48	3	MP:0009908
MousePheno	muscular ventricular septal defect	SLIT2 SHROOM3 ADAMTS6 ATP11A	1.38e-04	77	48	4	MP:0010420
MousePheno	abnormal interventricular septum muscular part morphology	SLIT2 SHROOM3 ADAMTS6 ATP11A	1.52e-04	79	48	4	MP:0010498
MousePheno	abnormal tongue position	SHROOM3 ACAN AXIN2	1.60e-04	31	48	3	MP:0031443
MousePheno	microphthalmia	SLIT2 SHROOM3 ADAMTS6 PRSS56 LAMA5 KIRREL1 AXIN2	2.17e-04	362	48	7	MP:0001297
MousePheno	ectopic ureteric bud	RET GEN1	2.40e-04	7	48	2	MP:0010980
MousePheno	abnormal eye size	SLIT2 SHROOM3 ADAMTS6 PRSS56 LAMA5 KIRREL1 AXIN2	2.70e-04	375	48	7	MP:0002697
MousePheno	perimembraneous ventricular septal defect	SLIT2 SHROOM3 ADAMTS6 ATP11A	2.74e-04	92	48	4	MP:0010418
MousePheno	abnormal interventricular septum membranous part morphology	SLIT2 SHROOM3 ADAMTS6 ATP11A	2.86e-04	93	48	4	MP:0008823
MousePheno	abnormal mesangial cell morphology	COL4A3 LAMA5 KIRREL1	2.95e-04	38	48	3	MP:0005327
MousePheno	kidney cyst	SLIT2 LAMA5 KIRREL1 LTBP3 RET	3.39e-04	177	48	5	MP:0003675
MousePheno	impaired branching involved in ureteric bud morphogenesis	LAMA5 RET GEN1	3.70e-04	41	48	3	MP:0004936
MousePheno	abnormal branching involved in ureteric bud morphogenesis	LAMA5 RET GEN1	4.87e-04	45	48	3	MP:0010981
MousePheno	abnormal renal glomerular capsule morphology	COL4A3 LAMA5 KIRREL1 RET	4.87e-04	107	48	4	MP:0002828
MousePheno	short basicranium	ACAN LTBP3	5.11e-04	10	48	2	MP:0030420
MousePheno	abnormal urinary system development	SLIT2 LAMA5 RET GEN1	5.60e-04	111	48	4	MP:0003942
MousePheno	absent neurocranium	SHROOM3 LAMA5	6.23e-04	11	48	2	MP:0000075
MousePheno	abnormal nephrogenic zone morphology	SLIT2 RET	6.23e-04	11	48	2	MP:0011334
MousePheno	abnormal heart and great artery attachment	SLIT2 SHROOM3 ADAMTS6 LAMA5 ATP11A	6.63e-04	205	48	5	MP:0010426
MousePheno	abnormal heart and great vessel attachment	SLIT2 SHROOM3 ADAMTS6 LAMA5 ATP11A	7.08e-04	208	48	5	MP:0010425
Domain	Peptidase_M12B_N	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	9.81e-08	39	55	5	IPR002870
Domain	Pep_M12B_propep	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	9.81e-08	39	55	5	PF01562
Domain	DISINTEGRIN_1	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	1.12e-07	40	55	5	PS00427
Domain	Reprolysin	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	1.12e-07	40	55	5	PF01421
Domain	ADAM_MEPRO	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	1.12e-07	40	55	5	PS50215
Domain	DISINTEGRIN_2	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	1.12e-07	40	55	5	PS50214
Domain	Peptidase_M12B	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	1.12e-07	40	55	5	IPR001590
Domain	Disintegrin_dom	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	1.27e-07	41	55	5	IPR001762
Domain	ADAM_spacer1	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15	5.72e-07	23	55	4	IPR010294
Domain	ADAM_spacer1	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15	5.72e-07	23	55	4	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15	6.84e-07	24	55	4	IPR013273
Domain	MetalloPept_cat_dom	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	3.97e-06	81	55	5	IPR024079
Domain	-	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	3.97e-06	81	55	5	3.40.390.10
Domain	CYSTEINE_SWITCH	ADAMTS12 ADAMTS16 ADAMTS15 ADAM30	6.29e-06	41	55	4	PS00546
Domain	Pept_M10_metallopeptidase	ADAMTS12 ADAMTS16 ADAMTS15 ADAM30	7.63e-06	43	55	4	IPR001818
Domain	ZINC_PROTEASE	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	1.01e-05	98	55	5	PS00142
Domain	PLAC	ADAMTS12 ADAMTS6 ADAMTS16	2.26e-05	19	55	3	PS50900
Domain	PLAC	ADAMTS12 ADAMTS6 ADAMTS16	2.26e-05	19	55	3	IPR010909
Domain	TSP_1	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15	3.52e-05	63	55	4	PF00090
Domain	TSP1	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15	3.99e-05	65	55	4	SM00209
Domain	TSP1_rpt	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15	3.99e-05	65	55	4	IPR000884
Domain	TSP1	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15	3.99e-05	65	55	4	PS50092
Domain	SAPAP	DLGAP2 DLGAP3	8.47e-05	5	55	2	IPR005026
Domain	GKAP	DLGAP2 DLGAP3	8.47e-05	5	55	2	PF03359
Domain	EGF-like_dom	SLIT2 ZAN LAMA5 ADAM30 LTBP2 LTBP3	8.87e-05	249	55	6	IPR000742
Domain	EGF_1	SLIT2 ZAN LAMA5 ADAM30 LTBP2 LTBP3	1.01e-04	255	55	6	PS00022
Domain	EGF-like_CS	SLIT2 ZAN LAMA5 ADAM30 LTBP2 LTBP3	1.15e-04	261	55	6	IPR013032
Domain	EGF_2	SLIT2 ZAN LAMA5 ADAM30 LTBP2 LTBP3	1.25e-04	265	55	6	PS01186
Domain	TB	LTBP2 LTBP3	1.77e-04	7	55	2	PF00683
Domain	Glyco_trans_14	GCNT3 GCNT1	2.36e-04	8	55	2	IPR003406
Domain	Branch	GCNT3 GCNT1	2.36e-04	8	55	2	PF02485
Domain	-	LTBP2 LTBP3	2.36e-04	8	55	2	3.90.290.10
Domain	TB	LTBP2 LTBP3	3.02e-04	9	55	2	PS51364
Domain	TB_dom	LTBP2 LTBP3	3.02e-04	9	55	2	IPR017878
Domain	Sushi	CSMD1 CSMD2 CR2	4.82e-04	52	55	3	PF00084
Domain	CCP	CSMD1 CSMD2 CR2	5.39e-04	54	55	3	SM00032
Domain	SUSHI	CSMD1 CSMD2 CR2	6.00e-04	56	55	3	PS50923
Domain	EGF_3	SLIT2 ZAN ADAM30 LTBP2 LTBP3	6.30e-04	235	55	5	PS50026
Domain	EGF	SLIT2 ZAN LAMA5 LTBP2 LTBP3	6.30e-04	235	55	5	SM00181
Domain	Sushi_SCR_CCP_dom	CSMD1 CSMD2 CR2	6.32e-04	57	55	3	IPR000436
Domain	PLAC	ADAMTS6 ADAMTS16	7.57e-04	14	55	2	PF08686
Domain	ACR	ADAMTS15 ADAM30	2.85e-03	27	55	2	SM00608
Domain	ADAM_Cys-rich	ADAMTS15 ADAM30	2.85e-03	27	55	2	IPR006586
Domain	EGF_Ca-bd_CS	SLIT2 LTBP2 LTBP3	2.93e-03	97	55	3	IPR018097
Domain	hEGF	SLIT2 LTBP3	3.06e-03	28	55	2	PF12661
Domain	EGF_CA	SLIT2 LTBP2 LTBP3	3.10e-03	99	55	3	PS01187
Domain	ASX_HYDROXYL	SLIT2 LTBP2 LTBP3	3.19e-03	100	55	3	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	SLIT2 LTBP2 LTBP3	3.76e-03	106	55	3	IPR000152
Domain	Q_MOTIF	DDX59 DDX17	5.31e-03	37	55	2	PS51195
Domain	RNA_helicase_DEAD_Q_motif	DDX59 DDX17	5.31e-03	37	55	2	IPR014014
Domain	EGF_CA	SLIT2 LTBP2 LTBP3	5.57e-03	122	55	3	SM00179
Domain	LAM_G_DOMAIN	SLIT2 LAMA5	5.59e-03	38	55	2	PS50025
Domain	EGF-like_Ca-bd_dom	SLIT2 LTBP2 LTBP3	5.83e-03	124	55	3	IPR001881
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS12 GCNT3 ADAMTS6 ADAMTS16 ADAMTS15 GCNT1	1.19e-06	109	45	6	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS12 GCNT3 ADAMTS6 ADAMTS16 ADAMTS15 GCNT1	1.32e-06	111	45	6	M27416
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15	6.87e-06	39	45	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15	6.87e-06	39	45	4	MM15165
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL4A3 COL28A1 ACAN ADAMTS16 LAMA5 LTBP2 LTBP3	4.18e-05	300	45	7	M610
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15	6.36e-05	68	45	4	M27303
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS12 ADAMTS6 ACAN ADAMTS16 ADAMTS15	8.83e-05	143	45	5	M27275
Pathway	WP_GENES_CONTROLLING_NEPHROGENESIS	SLIT2 KIRREL1 RET	3.67e-04	44	45	3	M39891
Pathway	REACTOME_KIDNEY_DEVELOPMENT	SLIT2 RET IRX2	4.19e-04	46	45	3	M48243
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL4A3 ACAN ADAMTS16 LAMA5	1.01e-03	140	45	4	M587
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTS12 ADAMTS6 ACAN ADAMTS16 ADAMTS15	1.15e-03	250	45	5	M27554
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL4A3 COL28A1 ACAN LTBP2 LTBP3	1.33e-03	258	45	5	MM14572
Pubmed	Metalloproteinase Adamts16 Is Required for Proper Closure of the Optic Fissure.	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15	3.24e-11	5	57	4	29625437
Pubmed	Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT).	SLIT2 RET IRX2 AXIN2	1.97e-07	31	57	4	29459093
Pubmed	8-Cysteine TGF-BP structural motifs are the site of covalent binding between mouse LTBP-3, LTBP-2, and latent TGF-beta 1.	LTBP2 LTBP3	2.64e-06	2	57	2	9602168
Pubmed	Mucin biosynthesis: epidermal growth factor downregulates core 2 enzymes in a human airway adenocarcinoma cell line.	GCNT3 GCNT1	2.64e-06	2	57	2	12600830
Pubmed	A genetic association study of CSMD1 and CSMD2 with cognitive function.	CSMD1 CSMD2	2.64e-06	2	57	2	27890662
Pubmed	Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein.	LTBP2 LTBP3	2.64e-06	2	57	2	7798248
Pubmed	The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia.	CSMD1 CSMD2	2.64e-06	2	57	2	21439553
Pubmed	Loss of CSMD1 or 2 may contribute to the poor prognosis of colorectal cancer patients.	CSMD1 CSMD2	2.64e-06	2	57	2	24408017
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	SLIT2 DLGAP2 DLGAP3 LAMA5 LTBP3 AXIN2 KIF1C AGAP3	3.55e-06	560	57	8	21653829
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15	7.22e-06	75	57	4	20637190
Pubmed	Identification of two new members of the CSMD gene family.	CSMD1 CSMD2	7.91e-06	3	57	2	12906867
Pubmed	The miRNA biogenesis factors, p72/DDX17 and KHSRP regulate the protein level of Ago2 in human cells.	DDX17 KHSRP	7.91e-06	3	57	2	27478153
Pubmed	Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.	LTBP2 LTBP3	7.91e-06	3	57	2	21700711
Pubmed	Molecular cloning and expression of a novel beta-1, 6-N-acetylglucosaminyltransferase that forms core 2, core 4, and I branches.	GCNT3 GCNT1	7.91e-06	3	57	2	9915862
Pubmed	Slit2 as a β-catenin/Ctnnb1-dependent retrograde signal for presynaptic differentiation.	SLIT2 AXIN2	7.91e-06	3	57	2	26159615
Pubmed	High-sensitivity O-glycomic analysis of mice deficient in core 2 {beta}1,6-N-acetylglucosaminyltransferases.	GCNT3 GCNT1	7.91e-06	3	57	2	20855471
Pubmed	Tumor suppressor LKB1 inhibits activation of signal transducer and activator of transcription 3 (STAT3) by thyroid oncogenic tyrosine kinase rearranged in transformation (RET)/papillary thyroid carcinoma (PTC).	STK11 RET	7.91e-06	3	57	2	17761947
Pubmed	Latent transforming growth factor-beta binding proteins (LTBPs)--structural extracellular matrix proteins for targeting TGF-beta action.	LTBP2 LTBP3	7.91e-06	3	57	2	10743502
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL4A3 SLIT2 COL28A1 LAMA5 LTBP2	1.03e-05	175	57	5	28071719
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	FLNC SHROOM3 DDX17 SMPDL3B RPL10 KHSRP KIF1C	1.28e-05	477	57	7	31300519
Pubmed	Genetic link between renal birth defects and congenital heart disease.	SLIT2 ADAMTS6 LAMA5	1.33e-05	28	57	3	27002738
Pubmed	Latent TGFβ-binding proteins regulate UCP1 expression and function via TGFβ2.	LTBP2 LTBP3	1.58e-05	4	57	2	34481123
Pubmed	Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.	LTBP2 LTBP3	1.58e-05	4	57	2	15611103
Pubmed	SLIT/ROBO1 signaling suppresses mammary branching morphogenesis by limiting basal cell number.	SLIT2 AXIN2	1.58e-05	4	57	2	21664580
Pubmed	Laminin compensation in collagen alpha3(IV) knockout (Alport) glomeruli contributes to permeability defects.	COL4A3 LAMA5	1.58e-05	4	57	2	17699809
Pubmed	Laminin-1 reexpression in Alport mouse glomerular basement membranes.	COL4A3 LAMA5	1.58e-05	4	57	2	12631063
Pubmed	Extracellular fibrillar structure of latent TGF beta binding protein-1: role in TGF beta-dependent endothelial-mesenchymal transformation during endocardial cushion tissue formation in mouse embryonic heart.	LTBP2 LTBP3	1.58e-05	4	57	2	9008713
Pubmed	The latent transforming growth factor beta binding protein (LTBP) family.	LTBP2 LTBP3	1.58e-05	4	57	2	11104663
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	DLGAP2 FLNC DLGAP3 LTBP2 CSMD2 KHSRP	1.66e-05	329	57	6	17474147
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	SLIT2 ADAMTS6 ACAN LAMA5	2.26e-05	100	57	4	25807483
Pubmed	Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse.	DLGAP2 DLGAP3	2.63e-05	5	57	2	15024750
Pubmed	Disruption of Gen1 Causes Congenital Anomalies of the Kidney and Urinary Tract in Mice.	RET GEN1	2.63e-05	5	57	2	29483821
Pubmed	Gen1 Modulates Metanephric Morphology Through Retinoic Acid Signaling.	RET GEN1	2.63e-05	5	57	2	30632787
Pubmed	SLIT2/ROBO1-miR-218-1-RET/PLAG1: a new disease pathway involved in Hirschsprung's disease.	SLIT2 RET	2.63e-05	5	57	2	25786906
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	COL4A3 SHROOM3 NEO1 DDX17 ADAMTS16 KIRREL1 RPL10 AGAP3	3.76e-05	777	57	8	35844135
Pubmed	Sialoadhesin ligand expression identifies a subset of CD4+Foxp3- T cells with a distinct activation and glycosylation profile.	GCNT3 GCNT1	3.94e-05	6	57	2	23408841
Pubmed	Mapping of human and murine genes for latent TGF-beta binding protein-2 (LTBP2).	LTBP2 LTBP3	3.94e-05	6	57	2	7719025
Pubmed	Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.	ADAMTS16 ADAMTS15	5.51e-05	7	57	2	11867212
Pubmed	Glycosyltransferase function in core 2-type protein O glycosylation.	GCNT3 GCNT1	5.51e-05	7	57	2	19349303
Pubmed	Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta.	LTBP2 LTBP3	5.51e-05	7	57	2	10930463
Pubmed	SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density.	DLGAP2 DLGAP3	5.51e-05	7	57	2	9115257
Pubmed	Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family.	DLGAP2 DLGAP3	5.51e-05	7	57	2	10527873
Pubmed	Tcf7l2 plays crucial roles in forebrain development through regulation of thalamic and habenular neuron identity and connectivity.	SLIT2 IRX2 AXIN2	6.43e-05	47	57	3	28219675
Pubmed	Identification of transcripts with enriched expression in the developing and adult pancreas.	RBPJL ADAMTS16 ADAMTS15 GCNT1 IRX2 KHSRP KIF1C	7.03e-05	624	57	7	18554416
Pubmed	Reptilian heart development and the molecular basis of cardiac chamber evolution.	SLIT2 IRX2	7.34e-05	8	57	2	19727199
Pubmed	Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities.	DLGAP2 DLGAP3	7.34e-05	8	57	2	19640847
Pubmed	Requirement for core 2 O-glycans for optimal resistance to helminth infection.	GCNT3 GCNT1	7.34e-05	8	57	2	23555902
Pubmed	Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome.	COL4A3 LAMA5	9.43e-05	9	57	2	10880400
Pubmed	Liver kinase B1 expression promotes phosphatase activity and abrogation of receptor tyrosine kinase phosphorylation in human cancer cells.	STK11 RET	9.43e-05	9	57	2	24285539
Pubmed	Lgr4-deficient mice showed premature differentiation of ureteric bud with reduced expression of Wnt effector Lef1 and Gata3.	RET AXIN2	9.43e-05	9	57	2	21523854
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	ACAN LAMA5 LTBP2 LTBP3	9.90e-05	146	57	4	27068509
Pubmed	ADAMTS: a novel family of extracellular matrix proteases.	ADAMTS12 ADAMTS6	1.18e-04	10	57	2	11167130
Pubmed	Novel mechanisms of early upper and lower urinary tract patterning regulated by RetY1015 docking tyrosine in mice.	SLIT2 RET	1.18e-04	10	57	2	22627285
Pubmed	Lrp4 regulates initiation of ureteric budding and is crucial for kidney formation--a mouse model for Cenani-Lenz syndrome.	RET AXIN2	1.44e-04	11	57	2	20454682
Pubmed	Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.	COL4A3 RET	1.44e-04	11	57	2	9731539
Pubmed	Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.	LAMA5 CSMD1 CSMD2	1.55e-04	63	57	3	11572484
Pubmed	Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.	SLIT2 DDX59 PLCH2 IRX2	1.62e-04	166	57	4	19906978
Pubmed	Role of Wnt5a-Ror2 signaling in morphogenesis of the metanephric mesenchyme during ureteric budding.	SLIT2 RET	1.72e-04	12	57	2	24891614
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	ADAMTS12 DDX17 GCNT3 ADAMTS6 ADAMTS15 ADAM30 KHSRP	1.85e-04	730	57	7	34857952
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	DDX17 ADAMTS6 ACAN KIRREL1 RPL10 KHSRP	1.92e-04	513	57	6	25798074
Pubmed	Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.	COL4A3 LAMA5	2.03e-04	13	57	2	12682087
Pubmed	Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5.	ZAN SLC12A9	2.03e-04	13	57	2	11239002
Pubmed	Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease.	ADAMTS16 RET	2.37e-04	14	57	2	31242448
Pubmed	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	ATP11A CSMD1	2.73e-04	15	57	2	23583980
Pubmed	The species-specific differences in the cAMP regulation of the tissue-type plasminogen activator gene between rat, mouse and human is caused by a one-nucleotide substitution in the cAMP-responsive element of the promoters.	ADAMTS16 RET	2.73e-04	15	57	2	7543410
Pubmed	Gestational diabetes mellitus induces congenital anomalies of the kidney and urinary tract in mice by altering RET/MAPK/ERK pathway.	SLIT2 RET	2.73e-04	15	57	2	38657443
Pubmed	Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.	COL4A3 LAMA5	2.73e-04	15	57	2	10625553
Pubmed	Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.	COL4A3 LAMA5	2.73e-04	15	57	2	9264260
Pubmed	Phenotypic analysis of mice completely lacking netrin 1.	SLIT2 NEO1	2.73e-04	15	57	2	26395479
Pubmed	Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation.	ACAN ADAMTS16	2.73e-04	15	57	2	38018454
Pubmed	Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state.	RET AXIN2	3.12e-04	16	57	2	18177851
Pubmed	ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.	ADAMTS16 LAMA5	3.12e-04	16	57	2	30579834
Pubmed	Molecular detection of maturation stages in the developing kidney.	COL4A3 RET	3.53e-04	17	57	2	33197428
Pubmed	Constitutive metanephric mesenchyme-specific expression of interferon-gamma causes renal dysplasia by regulating Sall1 expression.	RET AXIN2	3.53e-04	17	57	2	29771971
Pubmed	Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus.	COL4A3 KIRREL1	3.53e-04	17	57	2	18082680
Pubmed	Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.	ADAMTS6 ACAN	3.97e-04	18	57	2	35503090
Pubmed	Wnt/β-catenin promotes gastric fundus specification in mice and humans.	IRX2 AXIN2	3.97e-04	18	57	2	28052057
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	FLNC NEO1 LAMA5 AGAP3	4.26e-04	214	57	4	22199357
Pubmed	ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation.	SLIT2 AXIN2	4.43e-04	19	57	2	26116176
Pubmed	Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney.	SLIT2 RET	4.43e-04	19	57	2	16319112
Pubmed	The metalloproteinase-proteoglycans ADAMTS7 and ADAMTS12 provide an innate, tendon-specific protective mechanism against heterotopic ossification.	ADAMTS12 ACAN	4.43e-04	19	57	2	29618652
Pubmed	FAK-Src signalling is important to renal collecting duct morphogenesis: discovery using a hierarchical screening technique.	RET AXIN2	4.43e-04	19	57	2	23616926
Pubmed	Genetic mapping of five mouse genes encoding synaptotagmins.	ACAN HAL	4.43e-04	19	57	2	8747928
Pubmed	A digenic cause of cleft lip in A-strain mice and definition of candidate genes for the two loci.	ADAMTS16 IRX2	4.92e-04	20	57	2	15329828
Pubmed	Mdm4 controls ureteric bud branching via regulation of p53 activity.	RET AXIN2	5.43e-04	21	57	2	32464196
Pubmed	The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.	HAL AXIN2	5.43e-04	21	57	2	27088858
Pubmed	PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.	COL4A3 LAMA5	5.43e-04	21	57	2	27856617
Pubmed	Gli3 is required in Emx1+ progenitors for the development of the corpus callosum.	SLIT2 AXIN2	5.43e-04	21	57	2	23396189
Pubmed	Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.	COL28A1 LAMA5 LTBP2	5.52e-04	97	57	3	27559042
Pubmed	Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.	LAMA5 AXIN2	5.97e-04	22	57	2	28334989
Pubmed	Histone deacetylase 1 and 2 regulate Wnt and p53 pathways in the ureteric bud epithelium.	RET AXIN2	5.97e-04	22	57	2	25758227
Pubmed	Defining the membrane proteome of NK cells.	DDX17 CLCN5 MYO9B ALDH16A1 OASL ATP11A RPL10 KHSRP	6.06e-04	1168	57	8	19946888
Pubmed	Proteomics characterization of extracellular space components in the human aorta.	ACAN LAMA5 LTBP2	6.21e-04	101	57	3	20551380
Pubmed	Slit/Robo signaling modulates the proliferation of central nervous system progenitors.	SLIT2 AXIN2	6.53e-04	23	57	2	23083737
Pubmed	Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion.	LAMA5 AXIN2	6.53e-04	23	57	2	29981310
Pubmed	Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1.	DDX17 RPL10 KHSRP KIF1C	6.66e-04	241	57	4	23125841
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	DLGAP2 CLIP3 DLGAP3 ACAN AGAP3	6.97e-04	430	57	5	32581705
Pubmed	Nkx6.1 controls migration and axon pathfinding of cranial branchio-motoneurons.	NEO1 RET	7.12e-04	24	57	2	14534138
Pubmed	Anti-osteogenic function of a LIM-homeodomain transcription factor LMX1B is essential to early patterning of the calvaria.	ACAN AXIN2	7.12e-04	24	57	2	29852132
Pubmed	Human gingiva transcriptome during wound healing.	ADAMTS12 COL4A3 ADAMTS15	7.34e-04	107	57	3	28005267
Cytoband	7q22	ZAN SLC12A9	9.99e-04	38	56	2	7q22
Cytoband	Ensembl 112 genes in cytogenetic band chr8p23	DLGAP2 RP1L1 CSMD1	2.97e-03	234	56	3	chr8p23
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15	5.63e-08	19	37	4	50
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	ACAN CSMD1 CSMD2 CR2	5.42e-06	57	37	4	1179
GeneFamily	Latent transforming growth factor beta binding proteins	LTBP2 LTBP3	2.44e-05	4	37	2	628
GeneFamily	Glucosaminyl (N-acetyl) transferases/xylosyltransferases	GCNT3 GCNT1	1.13e-04	8	37	2	441
GeneFamily	DEAD-box helicases	DDX59 DDX17	3.33e-03	42	37	2	499
GeneFamily	Collagens	COL4A3 COL28A1	3.99e-03	46	37	2	490
Coexpression	NABA_MATRISOME	ADAMTS12 COL4A3 SLIT2 ADAMTS6 COL28A1 ACAN ADAMTS16 ADAMTS15 LAMA5 ADAM30 LTBP2 LTBP3	1.15e-06	1008	56	12	MM17056
Coexpression	NABA_MATRISOME	ADAMTS12 COL4A3 SLIT2 ADAMTS6 COL28A1 ACAN ADAMTS16 ADAMTS15 LAMA5 ADAM30 LTBP2 LTBP3	1.38e-06	1026	56	12	M5889
Coexpression	NABA_CORE_MATRISOME	COL4A3 SLIT2 COL28A1 ACAN LAMA5 LTBP2 LTBP3	1.72e-06	270	56	7	MM17057
Coexpression	NABA_CORE_MATRISOME	COL4A3 SLIT2 COL28A1 ACAN LAMA5 LTBP2 LTBP3	1.94e-06	275	56	7	M5884
Coexpression	HUTTMANN_B_CLL_POOR_SURVIVAL_UP	CLCN5 ADAMTS6 MYO9B ZSCAN18 LAMA5 ATP11A CR2	2.40e-06	284	56	7	M19993
Coexpression	FAN_EMBRYONIC_CTX_EX_4_EXCITATORY_NEURON	DLGAP2 LAMA5 CSMD1 CSMD2 KIF1C	2.82e-05	166	56	5	M39026
Coexpression	DESCARTES_FETAL_LIVER_MESOTHELIAL_CELLS	COL4A3 DLGAP2 FLNC ADAMTS15 LAMA5 AXIN2	5.43e-05	313	56	6	M40228
Coexpression	GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_UP	COL4A3 FLNC SHROOM3 SLC12A9 KIRREL1	6.85e-05	200	56	5	M7745
Coexpression	GSE11961_FOLLICULAR_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_DN	SLIT2 DLGAP3 NEO1 ZAN ADAMTS15	6.85e-05	200	56	5	M9341
Coexpression	HE_LIM_SUN_FETAL_LUNG_C3_GRIA2_POS_ARTERIAL_ENDO_CELL	ADAMTS6 LAMA5 GCNT1 TM6SF1	1.08e-04	115	56	4	M45752
Coexpression	NABA_ECM_REGULATORS	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	1.55e-04	238	56	5	M3468
Coexpression	FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_UP	GCNT3 ADAMTS6 COL28A1 ACAN ASPA FAM83D	1.66e-04	384	56	6	M798
Coexpression	NABA_ECM_REGULATORS	ADAMTS12 ADAMTS6 ADAMTS16 ADAMTS15 ADAM30	1.68e-04	242	56	5	MM17062
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	ADAMTS12 FLNC CLIP3 SHROOM3 NEO1 DDX17 ZSCAN18 KIRREL1 DMRTA1 LTBP2 GCNT1 RFXAP AXIN2	5.89e-05	1466	54	13	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#5	LAMA5 GCNT1 AXIN2 KHSRP	1.42e-04	104	54	4	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K5
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000	ADAMTS12 SLIT2 FLNC CLIP3 NEO1 SMPDL3B ZSCAN18 DMRTA1 AXIN2	1.44e-04	783	54	9	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000	SLIT2 CLIP3 CLCN5 ADAMTS16 LAMA5 GCNT1 TM6SF1 RFXAP GEN1	1.44e-04	783	54	9	gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000	ADAMTS12 SLIT2 FLNC CLIP3 NEO1 SMPDL3B ADAMTS16 DMRTA1 AXIN2	1.65e-04	797	54	9	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
CoexpressionAtlas	Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5	ADAMTS12 CLIP3 NEO1 LAMA5 KIRREL1 LTBP3 CSMD1	1.70e-04	466	54	7	GSM777050_500
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Sema3e_Kank4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLIT2 FLNC ADAMTS6 ACAN ADAMTS15 TM6SF1 CR2	3.84e-10	135	56	7	54b2aaf8d322e01a3ff6099c2422d68ecccf96b4
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC CLIP3 NEO1 ATP11A LTBP3 RPL10	1.71e-07	196	56	6	2029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL4A3 SHROOM3 SLC12A9 RBPJL ATP11A CSMD2	1.77e-07	197	56	6	b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_late\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL4A3 SHROOM3 SMPDL3B LAMA5 ATP11A IRX2	1.82e-07	198	56	6	1851b7f4198b42c21c934e2fbda39dbd65e2625c
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL4A3 SHROOM3 SMPDL3B LAMA5 ATP11A IRX2	1.82e-07	198	56	6	c477405b093f4e5374e57bcacf1fb204a0f7eb3b
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb\|Cerebellum / BrainAtlas - Mouse McCarroll V32	DLGAP3 ADAMTS16 KIRREL1 RET CSMD1	1.24e-06	149	56	5	6e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS12 FLNC ADAMTS6 ACAN GEN1	1.28e-06	150	56	5	afd651c654e715414eff64cf3a37378d057a56a2
ToppCell	wk_20-22-Epithelial-Airway_epithelial_progenitor\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL4A3 SMPDL3B LAMA5 ATP11A IRX2	2.11e-06	166	56	5	fcd0bd70b553789092249806ace324b77bd10481
ToppCell	wk_20-22-Epithelial-Airway_epithelial_progenitor-epi-stalk_late\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL4A3 SMPDL3B LAMA5 ATP11A IRX2	2.11e-06	166	56	5	b60954e5625743657d0fd9264b738b46e72fd8a6
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Tpbg\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLIT2 ACAN ADAMTS15 RET TM6SF1	2.11e-06	166	56	5	b4241f8d2a0aa910dbb0d0d5d3631a9b73453fe9
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	COL4A3 SHROOM3 LAMA5 ATP11A IRX2	3.05e-06	179	56	5	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A3 SHROOM3 LAMA5 ATP11A IRX2	3.05e-06	179	56	5	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|normal_Lung / Location, Cell class and cell subclass	ADAMTS12 FLNC ACAN ADAMTS16 LTBP2	3.49e-06	184	56	5	0b336489c10e8c3c957795dd845454f03404382b
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL4A3 SHROOM3 LAMA5 ATP11A IRX2	3.78e-06	187	56	5	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL4A3 SHROOM3 LAMA5 ATP11A IRX2	3.88e-06	188	56	5	eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ACAN PRSS56 ADAMTS15 DMRTA1 GCNT1	3.88e-06	188	56	5	9b95730ddd13eb4624321bab3ab4989414977ca3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 CLCN5 COL28A1 LTBP2 IRX2	4.09e-06	190	56	5	3dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	COL4A3 SHROOM3 LAMA5 ATP11A IRX2	4.19e-06	191	56	5	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 CLCN5 COL28A1 LTBP2 IRX2	4.30e-06	192	56	5	562df5e87038c500dd3a003fe5374cb31946b145
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CLCN5 ACAN RBPJL DMRTA1 GCNT1	4.30e-06	192	56	5	3a6f2c255da46a0b0f5b657b0f56f3d7798ae85a
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC CLIP3 ATP11A LTBP3 RPL10	4.30e-06	192	56	5	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	wk_20-22-Epithelial-Distal_epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL4A3 SMPDL3B LAMA5 ATP11A IRX2	4.75e-06	196	56	5	cd507ee2baf4f52d6498811b3510d3164b56311f
ToppCell	wk_20-22-Epithelial-Distal_epithelial-type_I_pneumocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL4A3 SMPDL3B LAMA5 ATP11A IRX2	4.75e-06	196	56	5	e24a7aaf41793abba66c1189d933ca05b14c1af9
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	ADAMTS12 SLIT2 ADAMTS16 LTBP2 CSMD2	4.87e-06	197	56	5	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar-AT1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A3 SHROOM3 SMPDL3B LAMA5 IRX2	5.00e-06	198	56	5	54228dd9a50616d2022712d162a419ed0327cabd
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P3\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ACAN RBPJL DMRTA1 IRX2	5.08e-06	90	56	4	a0baaf2b3cf07d457f0d242fc213689cba6fd449
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ACAN RBPJL DMRTA1 IRX2	5.08e-06	90	56	4	ab4b08c6ac8695b38f841c0ecf2bb2c032111d04
ToppCell	Biopsy_IPF-Epithelial-Transitional_AT2\|Biopsy_IPF / Sample group, Lineage and Cell type	COL4A3 LAMA5 ATP11A IRX2 KIF1C	5.12e-06	199	56	5	83ff8b7e472d1212324c05cc719b746d19e5e23b
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL4A3 SLC12A9 ATP11A LTBP3 IRX2	5.12e-06	199	56	5	a270630626df614f8605abddb7dee7c4d74f6149
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Transitional_AT2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	COL4A3 SHROOM3 SMPDL3B ATP11A IRX2	5.25e-06	200	56	5	dfa897ef5ce4744c77b6e5ee5a0d6d83229d1691
ToppCell	Biopsy_Other_PF-Epithelial-Transitional_AT2\|Biopsy_Other_PF / Sample group, Lineage and Cell type	COL4A3 SHROOM3 LAMA5 ATP11A IRX2	5.25e-06	200	56	5	1ba6327851aa61e9a1f1fe1671bc27929d93ac74
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Transitional_AT2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL4A3 SHROOM3 SMPDL3B ATP11A IRX2	5.25e-06	200	56	5	8d1c78dd829cbc290820d5118f24ff7f828a8622
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 CLIP3 COL28A1 ACAN CSMD2	5.25e-06	200	56	5	29054cf55e88e1ac81a562d8dd9af9b7c749321d
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Transitional_AT2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL4A3 SHROOM3 SMPDL3B ATP11A IRX2	5.25e-06	200	56	5	992bd6b1feac2afded6eb927ac95ddf5cfef961c
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 SLIT2 CLIP3 ADAMTS16 LTBP2	5.25e-06	200	56	5	54806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCell	Globus_pallidus\|World / BrainAtlas - Mouse McCarroll V32	DDX17 ZAN MYO9B LTBP3	1.92e-05	126	56	4	44b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS12 CLIP3 DDX59 AXIN2	2.31e-05	132	56	4	4152529611eeacf0c547e2a134d5b98c45426b13
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ACAN RBPJL DMRTA1 IRX2	2.38e-05	133	56	4	63d2f096ae47d9b587acc6c5fbd346e5e58842b8
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS12 FLNC ACAN GEN1	2.75e-05	138	56	4	c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCell	COVID-19_Mild-Neu_0\|World / 5 Neutrophil clusters in COVID-19 patients	ADAMTS12 ADAMTS16 CSMD1 IRX2	2.91e-05	140	56	4	93f024473b1bb3bf93ae776fd6a8fc5e93d013f0
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS12 FLNC ACAN GEN1	3.08e-05	142	56	4	67d4ff3483ae34f77c3325aa0fbd3462ca19ade4
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Itm2a\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLIT2 ACAN ADAMTS15 TM6SF1	3.25e-05	144	56	4	0bbe670454846cf9bc7464ae4e91488415c4111d
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CSMD1 CSMD2 METTL17 AGAP3	3.43e-05	146	56	4	2ac9b487a7991fdc15444aeb93533030e09825bb
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLIT2 SHROOM3 RP1L1 ADAMTS16	4.12e-05	153	56	4	9b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	SLIT2 LTBP2 CSMD1 TM6SF1	4.22e-05	154	56	4	511923b27469ea20f8bd82a9ec27119a6e884644
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLIT2 CLCN5 ACAN ADAMTS16	4.78e-05	159	56	4	c186bf05c61fac348cf41973827cced83fafd58a
ToppCell	10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-HSC/MPP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DLGAP2 SMPDL3B ADAMTS6 DMRTA1	5.02e-05	161	56	4	46b5d80d2d521fb69752aba4c10383e715a32002
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A3 RBPJL ATP11A IRX2	5.14e-05	162	56	4	06f5d6c0bb26fe9d5180bc2ebf2c54bf52e715f3
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A3 RBPJL ATP11A IRX2	5.14e-05	162	56	4	d0d9c18a73bc0bf4f38308ef2eee8ae20f6a7918
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ADAMTS12 CLIP3 PLCH2 ADAMTS15	5.27e-05	163	56	4	f21951e63188eb0c04675a8f81a0da495c26c007
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP2 ADAMTS15 LTBP2 TM6SF1	5.39e-05	164	56	4	a784f47f67a5eda84d58ad7d9400e3978edbb487
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP2 ADAMTS15 LTBP2 TM6SF1	5.39e-05	164	56	4	1a1795969673232191425dde84ab24ee6a98143f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP2 ADAMTS15 LTBP2 TM6SF1	5.39e-05	164	56	4	8f074940afdbda88a4b697a7ddc687e09a4b818b
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLIT2 ACAN KIRREL1 RET	5.92e-05	168	56	4	2eed7dc1a2aff11be024823c4323c42bc94362f6
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLIT2 ACAN ADAMTS15 TM6SF1	5.92e-05	168	56	4	2572a3dd4f3f619bd26a3cd6e60de43821d8bb64
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6\|TCGA-Liver / Sample_Type by Project: Shred V9	SLIT2 CLIP3 ADAMTS15 LTBP2	6.06e-05	169	56	4	e992530776cab922d0360b275fb9cb8bd0017b06
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NEO1 SMPDL3B PLCH2 LAMA5	6.34e-05	171	56	4	943fbca8a6ac04052a2a85aca7b21a3461cd96f7
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A3 SHROOM3 ATP11A IRX2	6.63e-05	173	56	4	b799c06a6a5754668e789f70c0c8bc1508568575
ToppCell	wk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL4A3 LAMA5 IRX2 AGAP3	6.78e-05	174	56	4	2cd6638b361ca05ab83d09ce657194aed97873b7
ToppCell	droplet-Tongue-nan-24m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHROOM3 OASL IRX2 KIF1C	7.09e-05	176	56	4	9739b0653c511ab017507a0c7ee4f6d7082e87db
ToppCell	droplet-Tongue-nan-24m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHROOM3 OASL IRX2 KIF1C	7.41e-05	178	56	4	a3176b2b335db22bb0fb71aafa5d7a287809396e
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	COL4A3 SHROOM3 LAMA5 IRX2	7.57e-05	179	56	4	d5763912a4ce7188535675e338799b856edb9dda
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A3 DLGAP3 ASPA LTBP3	7.74e-05	180	56	4	39ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCell	Mesenchymal_cells-Stromal_fibro.\|Mesenchymal_cells / Lineage and Cell class	COL28A1 ASPA DMRTA1 RPL10	7.90e-05	181	56	4	f8d914fdc06aaa75a4dc9158daf574ca28fa5432
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 CLCN5 KIRREL1 IRX2	7.90e-05	181	56	4	22363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCell	COPD-Epithelial-ATI\|World / Disease state, Lineage and Cell class	COL4A3 SHROOM3 LAMA5 IRX2	8.07e-05	182	56	4	e95d946a43b1579af199900bb0e3eacbb9d65300
ToppCell	COVID-19-lung-AT1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A3 SHROOM3 LAMA5 IRX2	8.25e-05	183	56	4	7b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell	IPF-Epithelial-ATI\|World / Disease state, Lineage and Cell class	COL4A3 SHROOM3 LAMA5 IRX2	8.25e-05	183	56	4	31fef35ecf30162662f24d335d8f0cceacc07039
ToppCell	IPF-Epithelial-ATI\|IPF / Disease state, Lineage and Cell class	COL4A3 SHROOM3 LAMA5 IRX2	8.25e-05	183	56	4	c0a3541c45bd0c587603521f392f42dd86c3c35b
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL4A3 SHROOM3 SLC12A9 ATP11A	8.42e-05	184	56	4	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A3 SHROOM3 LAMA5 ATP11A	8.42e-05	184	56	4	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL4A3 SHROOM3 LAMA5 IRX2	8.42e-05	184	56	4	29c95b814a0b1ad8734ed68b77df29c08594e5ec
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 CLCN5 KIRREL1 IRX2	8.42e-05	184	56	4	d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL4A3 LAMA5 IRX2 AGAP3	8.42e-05	184	56	4	cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 CLCN5 KIRREL1 IRX2	8.42e-05	184	56	4	8fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL4A3 LAMA5 IRX2 AGAP3	8.42e-05	184	56	4	bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A3 SHROOM3 LAMA5 ATP11A	8.42e-05	184	56	4	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	Control-Epithelial-ATI\|World / Disease state, Lineage and Cell class	COL4A3 SHROOM3 LAMA5 IRX2	8.60e-05	185	56	4	0563d5042bb96ecce8446fbf26d05ef7a45e23c5
ToppCell	390C-Fibroblasts-Fibroblast-F\|390C / Donor, Lineage, Cell class and subclass (all cells)	SLIT2 CLIP3 ADAMTS16 ADAMTS15	8.60e-05	185	56	4	2c1f14f77faeee2acb388d997c5a27a7fef79be1
ToppCell	390C-Fibroblasts-Fibroblast-F-\|390C / Donor, Lineage, Cell class and subclass (all cells)	SLIT2 CLIP3 ADAMTS16 ADAMTS15	8.60e-05	185	56	4	37db8e0b1f59274227f6fc2362167eb44bd080ef
ToppCell	PND01-03-samps-Epithelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	COL4A3 RBPJL ATP11A IRX2	8.60e-05	185	56	4	2b854df79cfe2cb4d2f9c2938a066e0aa3649325
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 SLIT2 ACAN ADAMTS15	8.60e-05	185	56	4	e87e6e097dc29ece8aea671935bde281b99b93ea
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL4A3 SHROOM3 ATP11A IRX2	8.60e-05	185	56	4	c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLIT2 CLIP3 COL28A1 ADAMTS15	8.60e-05	185	56	4	355b03c7ea438681e11a2b872c798c9ea26e1486
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS12 SLIT2 ASPA LTBP2	8.78e-05	186	56	4	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL4A3 SHROOM3 ATP11A IRX2	8.78e-05	186	56	4	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL4A3 ADAMTS15 LAMA5 GCNT1	8.78e-05	186	56	4	1587667e5084ac43505d027af925ba711e228150
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	FLNC ADAMTS15 CSMD1 RPL10	8.78e-05	186	56	4	e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLIT2 ACAN CSMD1 CSMD2	8.78e-05	186	56	4	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	Epithelial-alveolar_epithelial_cell_type_1\|World / Lineage, Cell type, age group and donor	COL4A3 SHROOM3 LAMA5 IRX2	8.78e-05	186	56	4	09d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell	COPD-Epithelial-ATI\|COPD / Disease state, Lineage and Cell class	COL4A3 SHROOM3 LAMA5 IRX2	8.78e-05	186	56	4	df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLIT2 ACAN CSMD1 CSMD2	8.78e-05	186	56	4	a95744b8649096bd7cfc3591a02841fa411085b3
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	COL4A3 SHROOM3 ATP11A IRX2	8.96e-05	187	56	4	11670a85db87cbb3e78022a589632173604b0940
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLCN5 COL28A1 LTBP2 IRX2	8.96e-05	187	56	4	7ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCell	PND01-03-samps-Epithelial-Alveolar_epithelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	COL4A3 RBPJL ATP11A IRX2	8.96e-05	187	56	4	23fe3cdd6cc9b067086a8392d104186d300298ea
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	COL4A3 SHROOM3 ATP11A IRX2	8.96e-05	187	56	4	0277d4e54bd4d48f30241c2951a569209423fee8
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	ADAMTS12 ADAMTS6 ADAMTS16 LTBP2	8.96e-05	187	56	4	a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Htra1)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ADAMTS6 CR2 GEN1	9.03e-05	69	56	3	54e5ede00ce2920158d1cc0ac8e718aa24a4342e
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Htra1)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ADAMTS6 CR2 GEN1	9.03e-05	69	56	3	c93a47ee777b560f69b705d5d597f3cb3a3f558a
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Htra1)--\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ADAMTS6 CR2 GEN1	9.03e-05	69	56	3	8946d7e433c232c56563a6c464152c0a8cdbdf92
Disease	stenosing tenosynovitis	ADAMTS6 LTBP2 LTBP3	1.33e-06	12	55	3	EFO_0010822
Disease	obsolete aging	COL4A3 GCNT3 ACAN ASPA LTBP2 LTBP3	1.33e-05	279	55	6	GO_0007568
Disease	severe acute respiratory syndrome, COVID-19	ADAMTS12 DLGAP2 CLCN5 ATP11A LTBP2 LTBP3 CSMD1	1.89e-05	447	55	7	EFO_0000694, MONDO_0100096
Disease	hemoglobin A1 measurement	MYO9B RP1L1 RCL1 ADAM30 DMRTA1 ATP11A KIF1C	4.95e-05	520	55	7	EFO_0007629
Disease	cholesteryl ester 16:2 measurement	LTBP2 LTBP3	7.12e-05	7	55	2	EFO_0021435
Disease	spleen volume	MYO9B DMRTA1 KIF1C	7.17e-05	43	55	3	EFO_0600047
Disease	disease progression measurement, Crohn's disease	ADAMTS6 DMRTA1 CSMD1	9.38e-05	47	55	3	EFO_0000384, EFO_0008336
Disease	cystic kidney disease (implicated_via_orthology)	SLIT2 LAMA5	1.52e-04	10	55	2	DOID:2975 (implicated_via_orthology)
Disease	Mitral valve prolapse, response to surgery	LTBP2 LTBP3	2.22e-04	12	55	2	EFO_0009951, HP_0001634
Disease	squamous cell carcinoma	ADAMTS12 ATP11A HAL	2.70e-04	67	55	3	EFO_0000707
Disease	Hypodontia	LTBP3 AXIN2	3.06e-04	14	55	2	C0020608
Disease	low density lipoprotein cholesterol measurement, response to selective serotonin reuptake inhibitor	ADAMTS6 CSMD2	3.53e-04	15	55	2	EFO_0004611, EFO_0005658
Disease	Stomach Carcinoma	STK11 AXIN2	7.00e-04	21	55	2	C0699791
Disease	albuminuria	COL4A3 SHROOM3 CSMD1	7.28e-04	94	55	3	EFO_0004285
Disease	sunburn	ADAM30 ATP11A HAL	7.74e-04	96	55	3	EFO_0003958
Disease	Renal glomerular disease	COL4A3 CLCN5	8.42e-04	23	55	2	C0268731
Disease	Glomerulopathy Assessment	COL4A3 CLCN5	8.42e-04	23	55	2	C4521256
Disease	S-7-hydroxywarfarin measurement	SHROOM3 CSMD1 CSMD2	1.15e-03	110	55	3	EFO_0803329
Disease	suicidal ideation	LTBP2 LTBP3	1.34e-03	29	55	2	EFO_0004320
Disease	cutaneous melanoma	ADAMTS12 ATP11A HAL	1.51e-03	121	55	3	EFO_0000389
Disease	uridine measurement	SLIT2 CSMD1	1.63e-03	32	55	2	EFO_0010546

Protein segments in the cluster

Peptide	Gene	Start	Entry
GGYSKPGPDACREEK	AGAP3	711	Q96P47
EIEKGGCGDPGIPAY	CSMD1	521	Q96PZ7
GCGDPGIPAYGKRTG	CSMD1	526	Q96PZ7
CGDPGIPAYGRREGS	CSMD2	521	Q7Z408
PYGLVGVPGCSGSKG	COL4A3	116	Q01955
PGIRKVAFCGAPEEG	ALDH16A1	241	Q8IZ83
VLKTPGCQSPGVGRY	AXIN2	446	Q9Y2T1
GGYPTGGKDEEIPCR	DLGAP2	416	Q9P1A6
NPEPKFGGKYCTGER	ADAMTS12	571	P58397
PTPANGGKYCEGVRV	ADAMTS15	546	Q8TE58
GGQCVKYGDEGPKPT	ADAMTS16	571	Q8TE57
DSPAPSGGGKYCLGE	ADAMTS6	586	Q9UKP5
PGGGGEVVFSCPVRK	RCL1	161	Q9Y2P8
PPGGGGTYLCLATEK	RBPJL	321	Q9UBG7
YCEKLPGPSGAGRIV	SMPDL3B	176	Q92485
AEPGEPICVVCGRYG	DDX59	101	Q5T1V6
QPRGAGEGGPYGCKD	FAM83D	136	Q9H4H8
CAYGPGLKGGLVGTP	FLNC	1066	Q14315
ELCRTYGKPDGPGDA	KIF1C	781	O43896
YCKLVGGPVAGGDPN	LAMA5	81	O15230
PGGGYEPKKDASEGC	IRX2	446	Q9BZI1
PREGCYGDKDEFPGV	ACAN	216	P16112
PACGGDKPGVRTVYL	ACAN	641	P16112
PEVYVSLIKACGGPG	OASL	171	Q15646
CEEVGYGGSIDSGPP	ADAM30	661	Q9UKF2
CLPYVPEKGTVGASG	HAL	241	P42357
CPEPIVPGGYKIRGS	CR2	91	P20023
GIPGYKGDKGERGEC	COL28A1	286	Q2UY09
ESGVGAVGCGYPRTP	DMRTA1	81	Q5VZB9
KGGELPDRPAGVGVY	CLCN5	481	P51795
GGYPTGGKDGEIPCR	DLGAP3	376	O95886
GDIDKGAPYAPCSGI	GCNT3	371	O95395
EICPSGKGYIPVEGA	LTBP2	1461	Q14767
GPVRGEVGADCPQGY	LTBP3	331	Q9NS15
GCDYLPKGVPGVGKE	GEN1	206	Q17RS7
GDGGKVECFIGSTPP	KIRREL1	406	Q96J84
TCIYGGAPKGPQIRD	DDX17	276	Q92841
DGSVGGVRYFICPPK	CLIP3	336	Q96DZ5
GDVSKGAPYPPCDGV	GCNT1	361	Q02742
GYVVQGCGPSPGART	SDIM1	21	Q6ZPB5
LKGGSESGEPYIPGV	METTL17	231	Q9H7H0
DGCGEPGKPGVYTRV	PRSS56	311	P0CW18
EYGSRIGGGIDVPVP	KHSRP	316	Q92945
IPDGCGVKYIPSRGP	RPL10	191	P27635
GGLYRCVVESGGPPK	NEO1	216	Q92859
EGYPGGRPTCAVNTK	SHROOM3	686	Q8TF72
NIGKGSYAIPGDCGP	STK11	266	Q15831
PGGSVGAGKPVRYLC	RFXAP	61	O00287
DGKTIPLGGDCTVYP	ASPA	266	P45381
GPRKSPDGGKSCVYI	ATP11A	491	P98196
CREVFGRGGQPGPKY	RP1L1	391	Q8IWN7
PRPCNGEGAGGAYER	PLCH2	1056	O75038
LLRPRGGPGYVDVCG	SLC12A9	731	Q9BXP2
SEYKEPGIARCAGPG	SLIT2	876	O94813
PGEPRGIKAGYGTCN	RET	596	P07949
GADEPGLSRGKPYAC	ZSCAN18	401	Q8TBC5
GQETYPGPGKVEGKA	TXNRD3NB	101	Q6F5E7
PGNIVGKYGTRICPA	TM6SF1	156	Q9BZW5
VGYGGGLCMEPRDAP	ZAN	2736	Q9Y493
CSYTYGRKGEPGVEP	MYO9B	1681	Q13459