Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

GABRP OR5AK2 HLA-DQB1 HLA-DQB2 CCR9 GPR52 TLR6 IL18RAP OR1L3 FZD4 OR10G6 GPR83 UNC5A OR8G5 OR5L2 NPBWR1 OR5V1 LPAR5 P2RY12 GPR35 ADGRL1 OR5AK3P OR8U3 OR8J1 ACKR4 GRM5 EDNRB OPRM1 IFNAR1 OR8G1 OR2C1 IFNGR1 OR12D3 P2RY6 CXCR6 OR51M1 TLR1 FZD10 OR4C13 MUSK HCRTR2

1.37e-10135320041GO:0004888
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR5AK2 CCR9 GPR52 OR1L3 FZD4 OR10G6 GPR83 OR8G5 OR5L2 NPBWR1 OR5V1 LPAR5 P2RY12 GPR35 ADGRL1 OR5AK3P OR8U3 OR8J1 ACKR4 GRM5 EDNRB OPRM1 OR8G1 OR2C1 OR12D3 P2RY6 CXCR6 OR51M1 FZD10 OR4C13 HCRTR2

1.13e-0988420031GO:0004930
GeneOntologyMolecularFunctionodorant binding

OR5AK2 OR8G5 OR5L2 OR5AK3P OR8U3 OR8J1 OR8G1 OR2C1 OR12D3

5.42e-061272009GO:0005549
GeneOntologyMolecularFunctioncytokine receptor activity

CCR9 IL18RAP FZD4 GPR35 ACKR4 IFNAR1 IFNGR1 CXCR6

5.94e-06972008GO:0004896
GeneOntologyMolecularFunctionimmune receptor activity

HLA-DQB1 HLA-DQB2 CCR9 IL18RAP FZD4 GPR35 ACKR4 IFNAR1 IFNGR1 CXCR6

6.60e-0616520010GO:0140375
GeneOntologyMolecularFunctioncyclin-dependent protein serine/threonine kinase activator activity

CCND1 CCNY CCNYL1 CCNT2

1.62e-05162004GO:0061575
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA2 BRIP1 ABCA13 NAIP WRNIP1 ATP9B RECQL5 DNAH9 RFC5 ATP8B2 ABCA5 ATP12A POLQ DHX34 TDRD12

4.05e-0544120015GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

ABCA2 BRIP1 ABCA13 NAIP WRNIP1 ATP9B DNAH14 ACSM3 RECQL5 DNAH9 ZNFX1 RFC5 ATP8B2 ABCA5 ATP12A POLQ DHX34 TDRD12

4.85e-0561420018GO:0140657
GeneOntologyMolecularFunctionhexosyltransferase activity

GCNT3 EXT1 GCNT2 UGT1A5 UGT1A4 UGT1A3 TMTC1 ALG3 WDFY3 HAS3

5.51e-0521120010GO:0016758
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC17A2 SLC29A3 ABCA2 ABCA13 SLCO1B3 MFSD4B SLC13A4 SLC16A9 SLC6A13 ABCA5 SLC15A2 SLC18A2 SLC25A1 SLC17A8 ATP12A

9.76e-0547720015GO:0022804
GeneOntologyMolecularFunctionolfactory receptor activity

OR5AK2 OR1L3 OR10G6 OR8G5 OR5L2 OR5V1 OR5AK3P OR8U3 OR8J1 OR8G1 OR2C1 OR12D3 OR51M1 OR4C13

1.19e-0443120014GO:0004984
GeneOntologyMolecularFunctionG protein-coupled chemoattractant receptor activity

CCR9 GPR35 ACKR4 CXCR6

1.23e-04262004GO:0001637
GeneOntologyMolecularFunctionchemokine receptor activity

CCR9 GPR35 ACKR4 CXCR6

1.23e-04262004GO:0004950
GeneOntologyMolecularFunctionsymporter activity

SLC17A2 MFSD4B SLC13A4 SLC16A9 SLC6A13 SLC15A2 SLC18A2 SLC17A8

1.38e-041502008GO:0015293
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

GCNT3 EXT1 GCNT2 UGT1A5 UGT1A4 UGT1A3 WDFY3 HAS3

1.58e-041532008GO:0008194
GeneOntologyMolecularFunctionhelicase activity

BRIP1 WRNIP1 RECQL5 ZNFX1 RFC5 POLQ DHX34 TDRD12

1.97e-041582008GO:0004386
GeneOntologyMolecularFunctionN-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity

GCNT3 GCNT2

2.97e-0432002GO:0008109
GeneOntologyMolecularFunctionribonucleoside binding

POLR1B POLR3B

2.97e-0432002GO:0032549
GeneOntologyMolecularFunctionG protein-coupled ADP receptor activity

P2RY12 P2RY6

2.97e-0432002GO:0001621
GeneOntologyMolecularFunctionDNA helicase activity

BRIP1 WRNIP1 RECQL5 RFC5 POLQ

3.90e-04622005GO:0003678
GeneOntologyMolecularFunctionglucuronosyltransferase activity

EXT1 UGT1A5 UGT1A4 UGT1A3

4.01e-04352004GO:0015020
GeneOntologyMolecularFunctionNAD+ nucleotidase, cyclic ADP-ribose generating

TLR6 IL18RAP TLR1

5.03e-04162003GO:0061809
GeneOntologyMolecularFunctiontransporter activity

SLC17A2 GABRP SLC29A3 ABCA2 ABCA13 PKD1L1 SLCO1B3 ATP9B MFSD4B RYR1 SLC13A4 SLC22A14 KCNK1 CACNA1B CACNA1E AQP10 SLC16A9 ATP8B2 OPRM1 SLC6A13 ABCA5 SLC15A2 SLC18A2 SLC25A1 SLC17A8 ATP12A

5.17e-04128920026GO:0005215
GeneOntologyMolecularFunctioncreatine transmembrane transporter activity

SLC16A9 SLC6A13

5.91e-0442002GO:0005308
GeneOntologyMolecularFunctionToll-like receptor 2 binding

TLR6 TLR1

5.91e-0442002GO:0035663
GeneOntologyMolecularFunctionglycosyltransferase activity

GCNT3 EXT1 GCNT2 UGT1A5 UGT1A4 UGT1A3 TMTC1 ALG3 WDFY3 HAS3

6.76e-0428820010GO:0016757
GeneOntologyMolecularFunctiontoxic substance binding

HLA-DQB2 ADGRL1 ASS1

7.23e-04182003GO:0015643
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC17A2 GABRP SLC29A3 ABCA2 ABCA13 PKD1L1 SLCO1B3 MFSD4B RYR1 SLC13A4 SLC22A14 KCNK1 CACNA1B CACNA1E AQP10 SLC16A9 OPRM1 SLC6A13 ABCA5 SLC15A2 SLC18A2 SLC25A1 SLC17A8 ATP12A

7.65e-04118020024GO:0022857
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC17A2 SLCO1B3 MFSD4B SLC13A4 SLC16A9 SLC6A13 SLC15A2 SLC18A2 SLC25A1 SLC17A8

8.34e-0429620010GO:0015291
GeneOntologyMolecularFunctionFAD binding

SQLE LDHD STEAP4 STEAP3

9.69e-04442004GO:0071949
GeneOntologyMolecularFunctionferric-chelate reductase (NADPH) activity

STEAP4 STEAP3

9.79e-0452002GO:0052851
GeneOntologyMolecularFunctionferric-chelate reductase activity

STEAP4 STEAP3

9.79e-0452002GO:0000293
GeneOntologyMolecularFunctioncupric reductase (NADH) activity

STEAP4 STEAP3

9.79e-0452002GO:0008823
GeneOntologyMolecularFunctioninterferon receptor activity

IFNAR1 IFNGR1

9.79e-0452002GO:0004904
GeneOntologyMolecularFunctionDNA/RNA hybrid binding

POLR1B POLR3B

9.79e-0452002GO:0071667
GeneOntologyMolecularFunctionprotein serine/threonine kinase activator activity

CCND1 CCNY CCNYL1 ALS2 CCNT2

1.12e-03782005GO:0043539
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

RYR1 CACNA1B CACNA1E OPRM1

1.15e-03462004GO:0005245
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC17A2 SLC13A4 SLC6A13 SLC15A2 SLC18A2 SLC17A8

1.27e-031192006GO:0015294
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC17A2 SLC13A4 SLC6A13 SLC18A2 SLC17A8

1.33e-03812005GO:0015370
GeneOntologyMolecularFunctionC-C chemokine receptor activity

CCR9 ACKR4 CXCR6

1.51e-03232003GO:0016493
GeneOntologyMolecularFunctionsingle-stranded DNA helicase activity

WRNIP1 RFC5 POLQ

1.51e-03232003GO:0017116
GeneOntologyMolecularFunctioncyclin-dependent protein serine/threonine kinase regulator activity

CCND1 CCNY CCNYL1 CCNT2

1.69e-03512004GO:0016538
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC17A2 SLC13A4 KCNK1 SLC6A13 SLC18A2 SLC17A8 ATP12A

1.71e-031712007GO:0015081
GeneOntologyMolecularFunctionC-C chemokine binding

CCR9 ACKR4 CXCR6

1.72e-03242003GO:0019957
GeneOntologyMolecularFunctionligase activity, forming carbon-nitrogen bonds

MTHFS IFNAR1 TTLL6 ASS1

1.95e-03532004GO:0016879
GeneOntologyMolecularFunctionneuropeptide receptor activity

GPR83 NPBWR1 OPRM1 HCRTR2

1.95e-03532004GO:0008188
GeneOntologyMolecularFunctionG protein-coupled opioid receptor activity

NPBWR1 OPRM1

2.03e-0372002GO:0004985
GeneOntologyMolecularFunctionoxidoreductase activity, acting on metal ions, NAD or NADP as acceptor

STEAP4 STEAP3

2.03e-0372002GO:0016723
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

HPS1 RIC8A RIC1 P2RY12 ALS2 DENND4C KNDC1 SOS1

2.35e-032312008GO:0005085
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC17A2 PKD1L1 RYR1 SLC13A4 KCNK1 CACNA1B CACNA1E OPRM1 SLC6A13 SLC18A2 SLC17A8 ATP12A

2.63e-0346520012GO:0046873
GeneOntologyMolecularFunctionC-X-C chemokine receptor activity

GPR35 CXCR6

2.69e-0382002GO:0016494
GeneOntologyMolecularFunctionretinoic acid binding

UGT1A5 UGT1A4 UGT1A3

2.70e-03282003GO:0001972
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA2 ATP9B ATP8B2

2.70e-03282003GO:0140326
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNA1B CACNA1E

3.43e-0392002GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNA1B CACNA1E

3.43e-0392002GO:0099626
GeneOntologyMolecularFunctionprotein kinase activator activity

CCND1 CCNY CCNYL1 ALS2 GRM5 CCNT2

3.94e-031492006GO:0030295
GeneOntologyMolecularFunctionlipopeptide binding

TLR6 TLR1

4.26e-03102002GO:0071723
GeneOntologyMolecularFunctionchemokine binding

CCR9 ACKR4 CXCR6

4.33e-03332003GO:0019956
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR5AK2 CCR9 GPR52 ADCY5 OR1L3 FZD4 OR10G6 GPR83 RIC8A PLCB4 CCL13 OR8G5 OR5L2 NPBWR1 OR5V1 LPAR5 P2RY12 GPR35 ADGRL1 OR5AK3P OR8U3 OR8J1 ACKR4 GRM5 EDNRB OPRM1 OR8G1 OR2C1 OR12D3 P2RY6 CXCR6 OR51M1 FZD10 OR4C13 HCRTR2

2.17e-07139520135GO:0007186
GeneOntologyBiologicalProcessphospholipase C-activating G protein-coupled receptor signaling pathway

GPR83 PLCB4 P2RY12 GPR35 GRM5 EDNRB OPRM1 P2RY6 HCRTR2

6.36e-061332019GO:0007200
GeneOntologyBiologicalProcesslocomotory behavior

ABCA2 GPR52 ADCY5 FZD4 VPS13A CACNA1B CACNA1E DSCAM ALS2 GRM5 OPRM1 SLC18A2

2.38e-0528420112GO:0007626
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR5AK2 TLR6 OR1L3 OR10G6 OR8G5 OR5L2 OR5V1 OR5AK3P OR8U3 OR8J1 OR8G1 OR2C1 OR12D3 OR51M1 TLR1 OR4C13

5.87e-0552420116GO:0009593
GeneOntologyBiologicalProcessdetection of stimulus

OR5AK2 PKD1L1 NAIP GPR52 TLR6 OR1L3 OR10G6 OR8G5 OR5L2 OR5V1 OR5AK3P OR8U3 OR8J1 OR8G1 OR2C1 OR12D3 OR51M1 TLR1 OR4C13

8.75e-0572220119GO:0051606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR5AK2 OR1L3 OR10G6 OR8G5 OR5L2 OR5V1 OR5AK3P OR8U3 OR8J1 OR8G1 OR2C1 OR12D3 OR51M1 OR4C13

9.20e-0543220114GO:0050911
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC17A2 PKD1L1 RYR1 SLC13A4 KCNK1 PLCB4 CACNA1B CACNA1E CHERP P2RY12 GPR35 STEAP4 EDNRB OPRM1 SLC6A13 SLC15A2 P2RY6 SLC18A2 MCUR1 SLC17A8 STEAP3 ATP12A

1.01e-0492220122GO:0098662
GeneOntologyCellularComponentIgG immunoglobulin complex

IGLC1 IGLC2 IGLC3 IGLC6

7.85e-06142024GO:0071735
GeneOntologyCellularComponentIgD immunoglobulin complex

IGLC1 IGLC3 IGLC6

1.74e-0562023GO:0071738
GeneOntologyCellularComponentIgE immunoglobulin complex

IGLC1 IGLC3 IGLC6

1.74e-0562023GO:0071742
GeneOntologyCellularComponentPET complex

EXD1 TDRD12

2.77e-0432022GO:1990923
GeneOntologyCellularComponentIgA immunoglobulin complex

IGLC1 IGLC3 IGLC6

3.71e-04152023GO:0071745
GeneOntologyCellularComponentIgM immunoglobulin complex

IGLC1 IGLC3 IGLC6

3.71e-04152023GO:0071753
GeneOntologyCellularComponentcalcium channel complex

CATSPERE PKD1L1 RYR1 CACNA1B CACNA1E

7.07e-04732025GO:0034704
Domain7tm_1

OR5AK2 CCR9 GPR52 OR1L3 OR10G6 GPR83 OR8G5 OR5L2 NPBWR1 OR5V1 LPAR5 P2RY12 GPR35 OR8U3 OR8J1 ACKR4 EDNRB OPRM1 OR8G1 OR2C1 OR12D3 P2RY6 CXCR6 OR51M1 OR4C13 HCRTR2

2.13e-0867720226PF00001
DomainG_PROTEIN_RECEP_F1_1

OR5AK2 CCR9 GPR52 OR1L3 OR10G6 GPR83 OR8G5 OR5L2 NPBWR1 OR5V1 LPAR5 P2RY12 GPR35 OR8U3 OR8J1 ACKR4 EDNRB OPRM1 OR8G1 OR2C1 OR12D3 P2RY6 CXCR6 OR51M1 OR4C13 HCRTR2

2.70e-0868520226PS00237
DomainG_PROTEIN_RECEP_F1_2

OR5AK2 CCR9 GPR52 OR1L3 OR10G6 GPR83 OR8G5 OR5L2 NPBWR1 OR5V1 LPAR5 P2RY12 GPR35 OR8U3 OR8J1 ACKR4 EDNRB OPRM1 OR8G1 OR2C1 OR12D3 P2RY6 CXCR6 OR51M1 OR4C13 HCRTR2

3.22e-0869120226PS50262
DomainGPCR_Rhodpsn

OR5AK2 CCR9 GPR52 OR1L3 OR10G6 GPR83 OR8G5 OR5L2 NPBWR1 OR5V1 LPAR5 P2RY12 GPR35 OR8U3 OR8J1 ACKR4 EDNRB OPRM1 OR8G1 OR2C1 OR12D3 P2RY6 CXCR6 OR51M1 OR4C13 HCRTR2

3.31e-0869220226IPR000276
DomainGPCR_Rhodpsn_7TM

OR5AK2 CCR9 GPR52 OR1L3 GPR83 OR8G5 OR5L2 NPBWR1 OR5V1 LPAR5 P2RY12 GPR35 OR8U3 OR8J1 ACKR4 EDNRB OPRM1 OR8G1 OR2C1 OR12D3 P2RY6 CXCR6 OR51M1 OR4C13 HCRTR2

7.11e-0867020225IPR017452
DomainNPIP

NPIPA1 NPIPA5 NPIPA3 NPIPA2 NPIPA7

2.60e-07142025IPR009443
DomainLRRC37AB_C

LRRC37A3 LRRC37A2 LRRC37A

4.95e-0642023IPR029423
DomainLRRC37AB_C

LRRC37A3 LRRC37A2 LRRC37A

4.95e-0642023PF14914
DomainLRRC37_N

LRRC37A3 LRRC37A2 LRRC37A

4.95e-0642023IPR032754
DomainLRRC37

LRRC37A3 LRRC37A2 LRRC37A

4.95e-0642023PF15779
DomainLRRC37A/B-like

LRRC37A3 LRRC37A2 LRRC37A

4.95e-0642023IPR015753
DomainMFS_dom

SLC17A2 SLCO1B3 MFSD4B SLC22A14 SLC16A9 SLC15A2 SLC18A2 SLC17A8

1.06e-041342028IPR020846
DomainCyclin_Y

CCNY CCNYL1

1.16e-0422022IPR012399
DomainMFS_1

SLC17A2 MFSD4B SLC22A14 SLC16A9 SLC18A2 SLC17A8

1.86e-04772026PF07690
DomainMFS

SLC17A2 MFSD4B SLC22A14 SLC16A9 SLC18A2 SLC17A8

1.86e-04772026IPR011701
DomainCYCLINS

CCND1 CCNY CCNYL1 CCNT2

2.22e-04282024PS00292
DomainABC_A

ABCA2 ABCA13 ABCA5

2.55e-04122023IPR026082
Domain-

POLR1B POLR3B

3.47e-04320222.40.270.10
DomainRNA_pol_RPB2_OB-fold

POLR1B POLR3B

3.47e-0432022IPR014724
DomainRNA_pol_bsu_CS

POLR1B POLR3B

3.47e-0432022IPR007121
DomainDNA-dir_RNA_pol_su2_6

POLR1B POLR3B

3.47e-0432022IPR007120
DomainRNA_pol_Rpb2_7

POLR1B POLR3B

3.47e-0432022PF04560
DomainRNA_pol_Rpb2_2

POLR1B POLR3B

3.47e-0432022PF04561
DomainRNA_pol_Rpb2_5

POLR1B POLR3B

3.47e-0432022PF04567
DomainRNA_pol_Rpb2_1

POLR1B POLR3B

3.47e-0432022PF04563
DomainRNA_pol_Rpb2_3

POLR1B POLR3B

3.47e-0432022PF04565
DomainRNA_pol_Rpb2_5

POLR1B POLR3B

3.47e-0432022IPR007647
DomainRNA_pol_Rpb2_3

POLR1B POLR3B

3.47e-0432022IPR007645
DomainRNA_pol_bsu_protrusion

POLR1B POLR3B

3.47e-0432022IPR007644
DomainRNA_pol_Rpb2_2

POLR1B POLR3B

3.47e-0432022IPR007642
DomainRNA_pol_Rpb2_7

POLR1B POLR3B

3.47e-0432022IPR007641
Domain-

POLR1B POLR3B

3.47e-04320222.40.50.150
DomainRNA_POL_BETA

POLR1B POLR3B

3.47e-0432022PS01166
Domain-

POLR1B POLR3B

3.47e-04320223.90.1110.10
DomainDNA-dir_RNA_pol_su2

POLR1B POLR3B

3.47e-0432022IPR015712
DomainRNA_pol_Rpb2_6

POLR1B POLR3B

3.47e-0432022PF00562
DomainOlfact_rcpt

OR5AK2 OR1L3 OR10G6 OR8G5 OR5L2 OR5V1 OR8U3 OR8J1 OR8G1 OR2C1 OR12D3 OR51M1 OR4C13

3.65e-0439320213IPR000725
DomainCyclin_N

CCND1 CCNY CCNYL1 CCNT2

4.25e-04332024PF00134
DomainCyclin_N

CCND1 CCNY CCNYL1 CCNT2

4.25e-04332024IPR006671
DomainChemokine_rcpt

CCR9 ACKR4 CXCR6

6.29e-04162023IPR000355
DomainArylacetamide_deacetylase

AADACL4 NCEH1

6.88e-0442022IPR017157
DomainSHR-BD

VPS13A VPS13B

6.88e-0442022IPR009543
DomainVPS13_C

VPS13A VPS13B

6.88e-0442022PF16909
DomainVPS13_C

VPS13A VPS13B

6.88e-0442022IPR031645
DomainSHR-BD

VPS13A VPS13B

6.88e-0442022PF06650
DomainCYCLIN

CCND1 CCNY CCNYL1 CCNT2

7.35e-04382024SM00385
Domain-

CCND1 CCNY CCNYL1 CCNT2

8.95e-044020241.10.472.10
DomainRNaseH-like_dom

EXD1 PIWIL1 RNASEH2A POLQ THAP12

9.03e-04692025IPR012337
DomainAAA

ABCA2 ABCA13 NAIP WRNIP1 DNAH9 RFC5 ABCA5

9.84e-041442027SM00382
DomainAAA+_ATPase

ABCA2 ABCA13 NAIP WRNIP1 DNAH9 RFC5 ABCA5

9.84e-041442027IPR003593
DomainToll-like_receptor

TLR6 TLR1

1.14e-0352022IPR017241
DomainAutophagy-rel_C

VPS13A VPS13B

1.14e-0352022IPR015412
DomainATG_C

VPS13A VPS13B

1.14e-0352022PF09333
DomainMFS

SLC17A2 SLCO1B3 SLC22A14 SLC16A9 SLC18A2 SLC17A8

1.14e-031082026PS50850
DomainCyclin-like

CCND1 CCNY CCNYL1 CCNT2

1.18e-03432024IPR013763
DomainUDPGT

UGT1A5 UGT1A4 UGT1A3

1.44e-03212023PF00201
Domain-

FZD4 FZD10 MUSK

1.44e-032120231.10.2000.10
DomainUDPGT

UGT1A5 UGT1A4 UGT1A3

1.44e-03212023PS00375
DomainUDP_glucos_trans

UGT1A5 UGT1A4 UGT1A3

1.44e-03212023IPR002213
DomainTIR

TLR6 IL18RAP TLR1

1.44e-03212023SM00255
Domain-

EXD1 PIWIL1 RNASEH2A POLQ

1.65e-034720243.30.420.10
DomainTIR

TLR6 IL18RAP TLR1

1.65e-03222023PF01582
DomainLIPASE_GDXG_SER

AADACL4 NCEH1

1.70e-0362022PS01174
DomainLIPASE_GDXG_HIS

AADACL4 NCEH1

1.70e-0362022PS01173
DomainDNA_pol3_clamp-load_cplx_C

WRNIP1 RFC5

1.70e-0362022IPR008921
Domain-

TLR6 IL18RAP TLR1

1.88e-032320233.40.50.10140
DomainTIR

TLR6 IL18RAP TLR1

2.13e-03242023PS50104
DomainFrizzled_dom

FZD4 FZD10 MUSK

2.13e-03242023IPR020067
DomainFZ

FZD4 FZD10 MUSK

2.13e-03242023PS50038
DomainFz

FZD4 FZD10 MUSK

2.13e-03242023PF01392
DomainProC_N

STEAP4 STEAP3

2.36e-0372022IPR028939
DomainAB_hydrolase_3

AADACL4 NCEH1

2.36e-0372022IPR013094
DomainCa_chan_IQ

CACNA1B CACNA1E

2.36e-0372022SM01062
DomainCa_chan_IQ

CACNA1B CACNA1E

2.36e-0372022PF08763
DomainAbhydrolase_3

AADACL4 NCEH1

2.36e-0372022PF07859
DomainVDCC_a1su_IQ

CACNA1B CACNA1E

2.36e-0372022IPR014873
DomainGPHH

CACNA1B CACNA1E

2.36e-0372022PF16905
DomainF420_oxidored

STEAP4 STEAP3

2.36e-0372022PF03807
DomainGPHH_dom

CACNA1B CACNA1E

2.36e-0372022IPR031649
DomainTIR_dom

TLR6 IL18RAP TLR1

2.41e-03252023IPR000157
DomainGlyco_trans_14

GCNT3 GCNT2

3.12e-0382022IPR003406
DomainChorein_N

VPS13A VPS13B

3.12e-0382022PF12624
DomainVPS13_N

VPS13A VPS13B

3.12e-0382022IPR026854
DomainMHC_II_b_N

HLA-DQB1 HLA-DQB2

3.12e-0382022PD000328
DomainBranch

GCNT3 GCNT2

3.12e-0382022PF02485
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

CCR9 GPR52 GPR83 NPBWR1 OR5V1 LPAR5 P2RY12 GPR35 ACKR4 EDNRB OPRM1 OR2C1 OR12D3 P2RY6 HCRTR2

6.05e-0826014315M39397
PathwayREACTOME_ATORVASTATIN_ADME

SLCO1B3 UGT1A5 UGT1A4 UGT1A3

1.27e-05151434MM15697
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC29A3 ABCA2 SLCO1B3 PSMD1 ATP9B MFSD4B ADCY5 RYR1 SLC13A4 NCEH1 AQP10 STEAP4 ATP8B2 SLC6A13 ABCA5 SLC15A2 SLC18A2 SLC25A1 SLC17A8 STEAP3 ATP12A

1.64e-0573614321M27287
PathwayWP_GPCRS_NONODORANT

CCR9 FZD4 NPBWR1 LPAR5 P2RY12 ADGRL1 GRM5 EDNRB OPRM1 P2RY6 CXCR6 HCRTR2

1.69e-0526614312MM15843
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

CCR9 GPR83 OR8G5 P2RY12 GPR35 EDNRB OPRM1 OR8G1 OR2C1 P2RY6

1.97e-0518614310MM15994
PathwayREACTOME_HEME_DEGRADATION

SLCO1B3 UGT1A5 UGT1A4 UGT1A3

4.34e-05201434MM14721
PathwayREACTOME_GPCR_LIGAND_BINDING

CCR9 FZD4 CCL13 NPBWR1 LPAR5 P2RY12 GPR35 ACKR4 GRM5 EDNRB OPRM1 P2RY6 CXCR6 FZD10 HCRTR2

7.22e-0546314315M507
PathwayREACTOME_SIGNALING_BY_GPCR

CCR9 ADCY5 FZD4 GPR83 PLCB4 CCL13 NPBWR1 LPAR5 P2RY12 GPR35 ACKR4 GRM5 EDNRB OPRM1 P2RY6 CXCR6 FZD10 HCRTR2 SOS1

8.72e-0570214319M746
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

CCR9 CCL13 NPBWR1 LPAR5 P2RY12 GPR35 ACKR4 EDNRB OPRM1 P2RY6 CXCR6 HCRTR2

1.36e-0433014312M18334
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

CCR9 CCL13 NPBWR1 LPAR5 P2RY12 GPR35 ACKR4 EDNRB OPRM1 P2RY6 CXCR6 HCRTR2

1.48e-0433314312MM14963
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

RYR1 CACNA1B CACNA1E

1.59e-04111433M47958
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC29A3 ABCA2 SLCO1B3 PSMD1 ATP9B RYR1 SLC13A4 NCEH1 STEAP4 ATP8B2 SLC6A13 ABCA5 SLC15A2 SLC18A2 SLC25A1 SLC17A8 STEAP3 ATP12A

1.82e-0468114318MM14985
PathwayREACTOME_METABOLISM_OF_PORPHYRINS

SLCO1B3 UGT1A5 UGT1A4 UGT1A3

2.93e-04321434MM14719
PathwayREACTOME_SIGNALING_BY_GPCR

CCR9 ADCY5 GPR83 PLCB4 CCL13 NPBWR1 LPAR5 P2RY12 GPR35 ACKR4 GRM5 EDNRB OPRM1 P2RY6 CXCR6 HCRTR2 SOS1

2.93e-0464614317MM14962
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR5AK2 OR1L3 OR10G6 OR8G5 OR5L2 OR5V1 OR8U3 OR8J1 OR8G1 OR2C1 OR12D3 OR51M1 OR4C13

3.24e-0441714313M4072
PathwayREACTOME_NETRIN_1_SIGNALING

DSCAML1 UNC5A DSCAM

4.25e-04151433MM14965
PathwayREACTOME_GPCR_LIGAND_BINDING

CCR9 CCL13 NPBWR1 LPAR5 P2RY12 GPR35 ACKR4 GRM5 EDNRB OPRM1 P2RY6 CXCR6 HCRTR2

4.34e-0443014313MM15160
Pubmed

Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling.

NPIPA1 NPIPA5 NPIPA3 NPIPA2

1.32e-094211418055785
Pubmed

Human immunoglobulin C lambda 6 gene encodes the Kern+Oz-lambda chain and C lambda 4 and C lambda 5 are pseudogenes.

IGLC1 IGLC2 IGLC3 IGLC6

9.04e-08821143122211
Pubmed

Clustered arrangement of immunoglobulin lambda constant region genes in man.

IGLC1 IGLC2 IGLC3 IGLC6

1.62e-07921146273747
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR5AK2 OR10G6 OR8G5 OR5L2 OR5V1 OR5AK3P OR8U3 OR8J1 OR8G1 OR2C1 OR12D3 OR51M1 OR4C13

1.89e-073402111311875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR5AK2 OR10G6 OR8G5 OR5L2 OR5V1 OR5AK3P OR8U3 OR8J1 OR8G1 OR2C1 OR12D3 OR51M1 OR4C13

1.89e-073402111311802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR5AK2 OR10G6 OR8G5 OR5L2 OR5V1 OR5AK3P OR8U3 OR8J1 OR8G1 OR2C1 OR12D3 OR51M1 OR4C13

2.09e-073432111332295537
Pubmed

Unraveling of the polymorphic C lambda 2-C lambda 3 amplification and the Ke+Oz- polymorphism in the human Ig lambda locus.

IGLC1 IGLC2 IGLC3

2.20e-073211312077254
Pubmed

Three-dimensional structure of a light chain dimer crystallized in water. Conformational flexibility of a molecule in two crystal forms.

IGLC1 IGLC2 IGLC3

2.20e-07321132515285
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR5AK2 OR10G6 OR8G5 OR5L2 OR5V1 OR5AK3P OR8U3 OR8J1 OR8G1 OR2C1 OR12D3 OR51M1 OR4C13

2.31e-073462111314611657
Pubmed

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

SLCO1B3 UGT1A5 UGT1A4 UGT1A3

2.69e-0710211423371916
Pubmed

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

SLCO1B3 UGT1A5 UGT1A4 UGT1A3

6.27e-0712211419419973
Pubmed

The three-dimensional structure of the fab' fragment of a human myeloma immunoglobulin at 2.0-angstrom resolution.

IGLC1 IGLC2 IGLC3

8.77e-07421134215080
Pubmed

Immunoglobulin lambda-chains. The complete amino acid sequence of a Bence-Jones protein.

IGLC1 IGLC2 IGLC3

8.77e-07421134883841
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A3 LRRC37A2 LRRC37A

8.77e-074211322419166
Pubmed

Comparative studies on the structure of the light chains of human immunoglobulins. IV. Assignment of a subsubgroup.

IGLC1 IGLC2 IGLC3

8.77e-07421136404900
Pubmed

Primary structure of the Mcg lambda chain.

IGLC1 IGLC2 IGLC3

8.77e-07421134415202
Pubmed

[Structural rule of antibodies. Primary structure of a monoclonal immunoglobulin-L-chain of the lambda type, subgroup IV (Bence-Jones-protein Kern). V. The complete amino acid sequence and its genetic interpretation].

IGLC1 IGLC2 IGLC3

8.77e-07421135549568
Pubmed

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

GCNT2 UGT1A5 UGT1A4 UGT1A3

1.26e-0614211414672974
Pubmed

Structure and function of immunoglobulins.

IGLC1 IGLC2 IGLC3 IGLC6

1.71e-0615211420176268
Pubmed

Amino acid sequence of the (lambda) light chain of a human myeloma immunoglobulin (IgG New).

IGLC1 IGLC2 IGLC3

2.18e-06521134814727
Pubmed

The amino acid sequence of a lambda type Bence-Jones protein. 3. The complete amino acid sequence and the location of the disulfide bridges.

IGLC1 IGLC2 IGLC3

2.18e-06521134909564
Pubmed

Genome-wide association of serum bilirubin levels in Korean population.

SLCO1B3 UGT1A5 UGT1A4 UGT1A3

2.95e-0617211420639394
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ABCA2 RYR1 SH3BP4 ZER1 RIC8A PLK3 ALOX5 RIC1 LPAR5 VPS39 PHF12 HECTD4 ADGRL1 SPATA20 GET4 INF2 STEAP3 PCNX1 WDFY3 HAS3 DHX34

4.31e-0611052112135748872
Pubmed

MAIT cell activation augments adenovirus vector vaccine immunogenicity.

IL18RAP IFNAR1 IFNGR1

4.34e-066211333510029
Pubmed

PIWI Slicing and EXD1 Drive Biogenesis of Nuclear piRNAs from Cytosolic Targets of the Mouse piRNA Pathway.

EXD1 PIWIL1 TDRD12

4.34e-066211326669262
Pubmed

Characterization of the two unique human anti-flavin monoclonal immunoglobulins.

IGLC1 IGLC2 IGLC3

1.21e-05821137737190
Pubmed

B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6.

HLA-DQB2 IFNAR1 IFNGR1

1.21e-058211327069113
Pubmed

Genetic determinants influencing human serum metabolome among African Americans.

UGT1A5 UGT1A4 UGT1A3 SLC6A13

1.27e-0524211424625756
Pubmed

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

UGT1A5 UGT1A4 UGT1A3

1.80e-059211322511988
Pubmed

T helper 1 effector memory CD4+ T cells protect the skin from poxvirus infection.

HLA-DQB2 IFNAR1 IFNGR1

1.80e-059211337083328
Pubmed

A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

UGT1A5 UGT1A4 UGT1A3

1.80e-05921131339448
Pubmed

Intracellular bacterial infection-induced IFN-gamma is critically but not solely dependent on Toll-like receptor 4-myeloid differentiation factor 88-IFN-alpha beta-STAT1 signaling.

TLR6 IFNAR1 IFNGR1

1.80e-059211315128825
Pubmed

Structure and expression of the human immunoglobulin lambda genes.

IGLC1 IGLC2 IGLC3

1.80e-05921132115572
Pubmed

Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer.

HLA-DQB2 IFNAR1 IFNGR1

1.80e-059211336736322
Pubmed

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

UGT1A5 UGT1A4 UGT1A3

2.56e-0510211323642732
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A3 LRRC37A2 LRRC37A

2.56e-0510211323064749
Pubmed

UDP-glucuronosyltransferases.

UGT1A5 UGT1A4 UGT1A3

2.56e-0510211311465080
Pubmed

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

UGT1A5 UGT1A4 UGT1A3

2.56e-0510211322558097
Pubmed

Adoptive cell therapy with tumor-specific Th9 cells induces viral mimicry to eliminate antigen-loss-variant tumor cells.

HLA-DQB2 CCR9 IFNAR1 CXCR6

2.78e-0529211434678150
Pubmed

The human olfactory receptor gene family.

OR5AK2 OR1L3 OR10G6 OR8G5 OR5L2 OR5V1 OR8U3 OR8J1 OR8G1 OR2C1 OR12D3 OR51M1 OR4C13

2.99e-055412111314983052
Pubmed

Japanese encephalitis virus induces vasodilation and severe lethality in adult and aged AG129 mice lacking alpha, beta and gamma interferon receptors.

IFNAR1 IFNGR1

3.66e-052211235931226
Pubmed

Species-specific recognition of Aspergillus fumigatus by Toll-like receptor 1 and Toll-like receptor 6.

TLR6 TLR1

3.66e-052211222315281
Pubmed

Feasibility and biological rationale of repurposing sunitinib and erlotinib for dengue treatment.

IFNAR1 IFNGR1

3.66e-052211229753658
Pubmed

Identification of novel ryanodine receptor 1 (RyR1) protein interaction with calcium homeostasis endoplasmic reticulum protein (CHERP).

RYR1 CHERP

3.66e-052211221454501
Pubmed

Cloning and characterization of cDNAs encoding mouse Ugt1.6 and rabbit UGT1.6: differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

UGT1A5 UGT1A3

3.66e-05221128068691
Pubmed

Blocking the R-type (Cav2.3) Ca2+ channel enhanced morphine analgesia and reduced morphine tolerance.

CACNA1B CACNA1E

3.66e-052211215610184
Pubmed

[DISTRIBUTION OF TWO-LOCUS HAPLOTYPES OF MICROBIAL COMPONENT SENSOR GENES TLR1 AND TLR6 IN MAJOR POPULATIONS OF SOUTH URALS].

TLR6 TLR1

3.66e-052211226470427
Pubmed

Immune response to mouse mammary tumor virus in mice lacking the alpha/beta interferon or the gamma interferon receptor.

IFNAR1 IFNGR1

3.66e-05221129525580
Pubmed

Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants.

TLR6 TLR1

3.66e-052211221852947
Pubmed

Interferon-dependent immunity is essential for resistance to primary dengue virus infection in mice, whereas T- and B-cell-dependent immunity are less critical.

IFNAR1 IFNGR1

3.66e-052211214990690
Pubmed

Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3: metabolite structure, kinetics, inducibility, and interindividual variability.

UGT1A4 UGT1A3

3.66e-052211224641623
Pubmed

In Vivo Imaging with Bioluminescent Enterovirus 71 Allows for Real-Time Visualization of Tissue Tropism and Viral Spread.

IFNAR1 IFNGR1

3.66e-052211227974562
Pubmed

Japanese Encephalitis Virus Vaccination Elicits Cross-Reactive HLA-Class I-Restricted CD8 T Cell Response Against Zika Virus Infection.

IFNAR1 IFNGR1

3.66e-052211233101303
Pubmed

A Targeted Computational Screen of the SWEETLEAD Database Reveals FDA-Approved Compounds with Anti-Dengue Viral Activity.

IFNAR1 IFNGR1

3.66e-052211233173007
Pubmed

Identification of two novel genes SLC15A2 and SLCO1B3 associated with maintenance dose variability of warfarin in a Chinese population.

SLCO1B3 SLC15A2

3.66e-052211229234073
Pubmed

Comparative Histopathologic Lesions of the Male Reproductive Tract during Acute Infection of Zika Virus in AG129 and Ifnar-/- Mice.

IFNAR1 IFNGR1

3.66e-052211229378173
Pubmed

Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin.

TLR6 TLR1

3.66e-052211211123271
Pubmed

Human down syndrome cell adhesion molecules (DSCAMs) are functionally conserved with Drosophila Dscam[TM1] isoforms in controlling neurodevelopment.

DSCAML1 DSCAM

3.66e-052211221645617
Pubmed

Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro.

IFNAR1 IFNGR1

3.66e-052211222908290
Pubmed

Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis.

IFNAR1 IFNGR1

3.66e-052211233149141
Pubmed

Type I, but not type II, interferon is critical in liver injury induced after ischemia and reperfusion.

IFNAR1 IFNGR1

3.66e-052211217935177
Pubmed

Genetic ancestry effects on the distribution of toll-like receptors (TLRs) gene polymorphisms in a population of the Atlantic Forest, São Paulo, Brazil.

TLR6 TLR1

3.66e-052211229175392
Pubmed

Trafficking and replication patterns reveal splenic macrophages as major targets of dengue virus in mice.

IFNAR1 IFNGR1

3.66e-052211222933295
Pubmed

Exonuclease Domain-Containing 1 Enhances MIWI2 piRNA Biogenesis via Its Interaction with TDRD12.

EXD1 TDRD12

3.66e-052211230257204
Pubmed

The Roles of TLR Gene Polymorphisms in Atherosclerosis: A Systematic Review and Meta-Analysis of 35,317 Subjects.

TLR6 TLR1

3.66e-052211228474755
Pubmed

Gamma interferon (IFN-γ) receptor restricts systemic dengue virus replication and prevents paralysis in IFN-α/β receptor-deficient mice.

IFNAR1 IFNGR1

3.66e-052211222973027
Pubmed

Meningeal lymphatic vessels mediate neurotropic viral drainage from the central nervous system.

IFNAR1 IFNGR1

3.66e-052211235524140
Pubmed

Dynamic roles of type I and type II IFNs in early infection with Mycobacterium tuberculosis.

IFNAR1 IFNGR1

3.66e-052211222566567
Pubmed

Modified mRNA Vaccines Protect against Zika Virus Infection.

IFNAR1 IFNGR1

3.66e-052211228222903
Pubmed

Partial IFN-alpha/beta and IFN-gamma receptor knockout trisomy 16 mouse fetuses show improved growth and cultured neuron viability.

IFNAR1 IFNGR1

3.66e-052211210714556
Pubmed

Frequent Zika Virus Sexual Transmission and Prolonged Viral RNA Shedding in an Immunodeficient Mouse Model.

IFNAR1 IFNGR1

3.66e-052211228199846
Pubmed

Targeting Vesicular Glutamate Transporter Machinery: Implications on Metabotropic Glutamate Receptor 5 Signaling and Behavior.

GRM5 SLC17A8

3.66e-052211232873747
Pubmed

A Dengue Virus Type 4 Model of Disseminated Lethal Infection in AG129 Mice.

IFNAR1 IFNGR1

3.66e-052211225938762
Pubmed

Zika Virus Infection in the Ovary Induces a Continuously Elevated Progesterone Level and Compromises Conception in Interferon Alpha/Beta Receptor-Deficient Mice.

IFNAR1 IFNGR1

3.66e-052211234730391
Pubmed

A Multitrait Locus Regulates Sarbecovirus Pathogenesis.

CCR9 CXCR6

3.66e-052211235862771
Pubmed

Mice lacking alpha/beta and gamma interferon receptors are susceptible to junin virus infection.

IFNAR1 IFNGR1

3.66e-052211220926559
Pubmed

Characterization of a model of lethal dengue virus 2 infection in C57BL/6 mice deficient in the alpha/beta interferon receptor.

IFNAR1 IFNGR1

3.66e-052211222815273
Pubmed

Bacterial-induced or passively administered interferon gamma conditions the lung for early control of SARS-CoV-2.

IFNAR1 IFNGR1

3.66e-052211238086794
Pubmed

CD8 T cells specific for lymphocytic choriomeningitis virus require type I IFN receptor for clonal expansion.

IFNAR1 IFNGR1

3.66e-052211216585541
Pubmed

The interdependent, overlapping, and differential roles of type I and II IFNs in the pathogenesis of experimental autoimmune encephalomyelitis.

IFNAR1 IFNGR1

3.66e-052211223960239
Pubmed

A non-mouse-adapted enterovirus 71 (EV71) strain exhibits neurotropism, causing neurological manifestations in a novel mouse model of EV71 infection.

IFNAR1 IFNGR1

3.66e-052211222130542
Pubmed

The magnitude of dengue virus NS1 protein secretion is strain dependent and does not correlate with severe pathologies in the mouse infection model.

IFNAR1 IFNGR1

3.66e-052211222419801
Pubmed

A Mouse Model of PPRV Infection for Elucidating Protective and Pathological Roles of Immune Cells.

IFNAR1 IFNGR1

3.66e-052211233912160
Pubmed

Role of TLR1 and TLR6 in the host defense against disseminated candidiasis.

TLR6 TLR1

3.66e-052211218036178
Pubmed

The association of genetic variants in toll-like receptor 2 subfamily with allergy and asthma after hospitalization for bronchiolitis in infancy.

TLR6 TLR1

3.66e-052211224445834
Pubmed

Negligible contribution of M2634V substitution to ZIKV pathogenesis in AG6 mice revealed by a bacterial promoter activity reduced infectious clone.

IFNAR1 IFNGR1

3.66e-052211230002446
Pubmed

Positive selection of a gene family during the emergence of humans and African apes.

NPIPA1 NPIPA8

3.66e-052211211586358
Pubmed

A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice.

IFNAR1 IFNGR1

3.66e-052211231243154
Pubmed

Mucin biosynthesis: molecular cloning and expression of mouse mucus-type core 2 beta1,6 N-acetylglucosaminyltransferase.

GCNT3 GCNT2

3.66e-052211217591617
Pubmed

Toll-like Receptor 1 743 A>G, 1805 T>G & Toll-like Receptor 6 745 C>T gene polymorphism and tuberculosis: a case control study of north Indian population from Agra (India).

TLR6 TLR1

3.66e-052211224984237
Pubmed

Interferon partly dictates a divergent transcriptional response in poxvirus-infected and bystander inflammatory monocytes.

IFNAR1 IFNGR1

3.66e-052211236417857
Pubmed

Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2.

IFNAR1 IFNGR1

3.66e-052211220592088
Pubmed

Functional interferon system is required for clearance of lassa virus.

IFNAR1 IFNGR1

3.66e-052211222238311
Pubmed

Macrophages from nonobese diabetic mouse have a selective defect in IFN-γ but not IFN-α/β receptor pathway.

IFNAR1 IFNGR1

3.66e-052211222396045
Pubmed

Both viral and host factors contribute to neurovirulence of bovine herpesviruses 1 and 5 in interferon receptor-deficient mice.

IFNAR1 IFNGR1

3.66e-052211215016885
Pubmed

Rotavirus Reprograms Multiple Interferon Receptors and Restricts Their Intestinal Antiviral and Inflammatory Functions.

IFNAR1 IFNGR1

3.66e-052211231896593
Pubmed

SNPs in the exons of Toll-like receptors are associated with susceptibility to type 1 diabetes in Chinese population.

TLR6 TLR1

3.66e-052211225261617
Pubmed

Adaptation of enterovirus 71 to adult interferon deficient mice.

IFNAR1 IFNGR1

3.66e-052211223527208
Pubmed

Interferon gamma regulates acute and latent murine cytomegalovirus infection and chronic disease of the great vessels.

IFNAR1 IFNGR1

3.66e-05221129687534
Pubmed

Protection from secondary dengue virus infection in a mouse model reveals the role of serotype cross-reactive B and T cells.

IFNAR1 IFNGR1

3.66e-052211222131327
Cytoband16p13.11

NPIPA1 ACSM3 NPIPA5 NPIPA3 NPIPA2

6.15e-0823211516p13.11
GeneFamilyCyclins

CCND1 CCNY CCNYL1 CCNT2

7.98e-05281504473
GeneFamilySolute carriers

SLC17A2 SLC29A3 SLCO1B3 SLC13A4 SLC35F3 SLC22A14 SLC16A9 SLC6A13 SLC15A2 SLC18A2 SLC25A1 SLC17A8

1.15e-0439515012752
GeneFamilyATP binding cassette subfamily A

ABCA2 ABCA13 ABCA5

1.91e-04141503805
GeneFamilyInterferon receptors

IFNAR1 IFNGR1

6.73e-0451502599
GeneFamilyProteases, serine|STEAP family

STEAP4 STEAP3

6.73e-04515021324
GeneFamilyGlucosaminyl (N-acetyl) transferases/xylosyltransferases

GCNT3 GCNT2

1.85e-0381502441
GeneFamilyUDP glucuronosyltransferases

UGT1A5 UGT1A4 UGT1A3

2.33e-03321503363
GeneFamilyOlfactory receptors, family 5

OR5AK2 OR5L2 OR5V1 OR5AK3P OR8U3

2.42e-031121505152
GeneFamilyCD molecules|Toll like receptors

TLR6 TLR1

2.95e-03101502948
GeneFamilyPurinergic receptors P2Y

P2RY12 P2RY6

2.95e-03101502213
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD4 FZD10

3.58e-03111502286
CoexpressionGSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_UP

RPP40 SQLE TLR6 TBC1D32 RECQL5 ZER1 ALOX5 HEATR3 SLC15A2 HCRTR2

4.44e-0620020610M3573
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EXD1 RYR1 DNAH9 CACNA1B CACNA1E SLC16A9 DSCAM ASS1 PDZD2 TDRD12

7.40e-09167210103edb0570e583bb527165bcd8a4c25a042054043b
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SQLE LDHD ACSM3 SLC22A14 KCNK1 SLC16A9 SLC6A13 SLC15A2

1.05e-061622108de0fde4310a56dc96bfc134c44d104993526d9bc
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|390C / Donor, Lineage, Cell class and subclass (all cells)

CATSPERE HLA-DQB1 NAIP TLR6 CCL13 P2RY6 TLR1 WDFY3

1.45e-0616921082c851b2703c7b8b656026f996f5fc027e4a79b36
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CATSPERE HLA-DQB1 TLR6 CCL13 IFNGR1 P2RY6 TLR1 WDFY3

1.72e-0617321081f725ff16e28636b20ef26f3fa9be8b47c89378d
ToppCellfacs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR9 CCND1 SH3BP4 CACNA1E C6orf62 P2RY12 ABCA5 CARD11

1.96e-06176210874f851a398c7562dd713bc0d8d488c0037243112
ToppCellfacs-Marrow-T_cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR9 CCND1 SH3BP4 CACNA1E C6orf62 P2RY12 ABCA5 CARD11

1.96e-06176210831b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCellmyeloid-Dendritic_cell-Plasmacytoid_dendritic_cell|myeloid / Lineage, cell class and subclass

GPR52 SLC35F3 KCNK1 PLCB4 SLC18A2 CARD11 IGLC2 IGLC3

2.13e-061782108f75591988bbbeba073b66329a3437cb9b02f7648
ToppCellfacs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC29A3 CCR9 CCND1 SH3BP4 CACNA1E P2RY12 ABCA5 CARD11

2.32e-061802108bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCellfacs-Marrow-B-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC29A3 CCR9 CCND1 SH3BP4 CACNA1E P2RY12 ABCA5 CARD11

2.32e-06180210882965ed1b72a1873c24dd4553d39681596057316
ToppCellfacs-Marrow-B-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC29A3 CCR9 CCND1 SH3BP4 CACNA1E P2RY12 ABCA5 CARD11

2.32e-061802108839defb40f7cfb2711e9025194de636533f51bcd
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DQB1 HLA-DQB2 CCND1 SH3BP4 ALOX5 LPAR5 P2RY12 P2RY6

2.73e-0618421081c56378b3888c46258d446b47de4d6282fe74b0d
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HLA-DQB1 HLA-DQB2 CCND1 SH3BP4 ALOX5 LPAR5 P2RY12 P2RY6

2.73e-061842108a45980306c4e697a2703bed72a7b48fb23d942f4
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

BRIP1 CCR9 SLC13A4 SLC6A13 STEAP3 FZD10 MUSK

3.47e-061342107d29ac8152dc581c0da2430d06cd259ac0eded808
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

BRIP1 CCR9 SLC13A4 SLC6A13 STEAP3 FZD10 MUSK

3.47e-061342107459c39df15d3cf9144ce7827e8d14830d31353bb
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

BRIP1 CCR9 SLC13A4 SLC6A13 STEAP3 FZD10 MUSK

3.47e-061342107d065449ca3679e4818b74fb7302cc7f1ce62f691
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Apod_(Apod)|Cerebellum / BrainAtlas - Mouse McCarroll V32

BRIP1 CCR9 SLC13A4 SLC6A13 STEAP3 FZD10 MUSK

3.47e-0613421070be389f416818a22e80098dd809fdf45b14171e8
ToppCellcellseq-Epithelial-Epithelial_Glandular-Goblet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GABRP GCNT3 ABCA13 KCNK1 SLC16A9 SLC15A2 ASS1 ATP12A

3.88e-06193210871bf8fb5314b79cb30f4eb9c8459b21f10cd6d35
ToppCellcellseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GABRP GCNT3 ABCA13 KCNK1 SLC16A9 SLC15A2 ASS1 ATP12A

3.88e-061932108b05e110b13d35d34294357c8e1c4fd23bf4b6c92
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

LRRC37A3 USP25 EXT1 CCNY PLCB4 WDFY3 VPS13B SOS1

4.87e-06199210894b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GCNT3 SH3BP4 PLCB4 DOP1B CACNA1E SLC16A9 CPNE4 ATP12A

5.05e-062002108ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DQB1 HLA-DQB2 NAIP ALOX5 LPAR5 P2RY12 TLR1 CARD11

5.05e-06200210827f498bcd706d0751091662996795b5270e46f14
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PIWIL1 CFAP47 OPRM1 WDR87 SLC17A8 CARD11

5.92e-06952106ffbf3e362384c87b9db690ed39cd215e1f68375c
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

TENM2 RYR1 DNAH9 CACNA1B DSCAM GRM5 CPNE4

1.07e-0515921075335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellHealthy/Control-Treg|World / Disease group and Cell class

CCR9 PLCL1 ATP8B2 RCAN3 CXCR6 TSPAN6 TDRD12

1.16e-051612107457297cda5c9cee3bcc069fdecbbe24def027e5f
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

GCNT3 HLA-DQB1 HLA-DQB2 GPR83 SLC16A9 OR5V1 CARD11

1.16e-051612107cd41abb7ae659d3d314281783a0aaad562b26037
ToppCelltumor_Lung-Myeloid_cells-Pleural_Mac|tumor_Lung / Location, Cell class and cell subclass

HLA-DQB1 HLA-DQB2 NAIP CCL13 FER1L5 SLC6A13 P2RY6

1.21e-0516221079ac3242511315224ed94582aca9e9a3786cd01a0
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRP GCNT3 SLC15A2 ASS1 CPNE4 ATP12A TDRD12

1.59e-05169210740b557549fe08c5dc9dba359af35993d68d1640a
ToppCellfacs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC29A3 CCR9 CCND1 SH3BP4 P2RY12 ABCA5 CARD11

1.71e-0517121076a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCellfacs-Marrow-T-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC29A3 CCR9 CCND1 SH3BP4 P2RY12 ABCA5 CARD11

1.71e-051712107e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 LDHD KCNK1 NCEH1 SLC6A13 SLC15A2 STEAP3

1.99e-051752107076ad81d6cbeea5512393d192af3ab5aa1f82975
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

HLA-DQB1 HLA-DQB2 MFSD4B MTHFS FRY INF2 SLC18A2

1.99e-051752107da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 LDHD KCNK1 NCEH1 SLC6A13 SLC15A2 STEAP3

1.99e-051752107445ccb9744a3a9ff37164c532afbe769d306b6c8
ToppCellICU-NoSEP-Myeloid-cDC1|ICU-NoSEP / Disease, Lineage and Cell Type

HLA-DQB1 HLA-DQB2 CCND1 SH3BP4 C2orf81 P2RY6 TSPAN6

2.14e-05177210733cd2c183ee8b597012efcbcae72131ac6beaf4e
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR9 SQLE CCND1 SH3BP4 P2RY12 GPR35 IFNAR1

2.22e-051782107742ee0cb8cb585a5e34bd5b20aebe9bb99756e0c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DSCAML1 SH3BP4 KCNK1 ADAMTS18 PLCL1 DSCAM ABCA5

2.30e-051792107e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KBTBD3 TLR6 MED23 P2RY12 SLC15A2 P2RY6 TLR1

2.30e-0517921076eb84fe9691ad40127b2d1f1c672428333c8fab4
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KBTBD3 TLR6 MED23 P2RY12 SLC15A2 P2RY6 TLR1

2.30e-0517921072c3abd646d2c8992e8ff76a824eab5beba8ba4c6
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR9 INPP4B ALOX5 LRRC9 SLC6A13 CXCR6 FZD10

2.38e-05180210767b062f2ef7e20f392e00c646f4985c415d40de9
ToppCellsevere-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ACSM3 TMEM164 ALS2 ATP8B2 FRY TEX30 SLC18A2

2.38e-051802107ac03812b1409435c55d323a7516deeac82bd3509
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-Alox5+_Lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR9 INPP4B ALOX5 LRRC9 SLC6A13 CXCR6 FZD10

2.38e-051802107b28363626f4d2a552abde3434cc1df2e2121aba5
ToppCellLV|World / Chamber and Cluster_Paper

GCNT2 TENM2 INPP4B NCEH1 PLCB4 PLCL1 PDZD2

2.38e-0518021075ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADCY5 INPP4B PLCB4 PLCL1 STEAP4 EDNRB PDZD2

2.47e-05181210733cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_9|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SH3BP4 SLC13A4 CCL13 CACNA1B P2RY6 PADI6

2.48e-0512221067dabf8b4c34a3714f45c3a99c1aa159e2d0b7e9c
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_9|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SH3BP4 SLC13A4 CCL13 CACNA1B P2RY6 PADI6

2.48e-051222106489a01c71882be5a6d71a19d06574698988c20f6
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC13A4 SLC22A14 SLC6A13 TTLL6 FZD10 MUSK

2.60e-05123210628be15b759c152662b29c323b1cc3f02f7830dbe
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLCO1B3 DTX3L INPP4B FZD4 PLCB4 EDNRB IFNAR1

2.65e-051832107e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellPBMC-Mild-cDC_9|Mild / Compartment, Disease Groups and Clusters

DTX3L SLC13A4 CCL13 CACNA1B P2RY12 P2RY6 DHX34

2.74e-0518421072e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

GCNT2 TENM2 INPP4B NCEH1 PLCL1 FRY PDZD2

2.84e-0518521076baccb26f999145e51b91d94315bf8d4655bef31
ToppCell3'_v3-blood-Myeloid_Dendritic-DC1|blood / Manually curated celltypes from each tissue

HLA-DQB1 HLA-DQB2 CCND1 SH3BP4 NPIPA3 P2RY6 MCUR1

3.15e-051882107411d4dd5c9dee7ebd8db352640cf009e7b033ba9
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DSCAML1 SLC35F3 DSCAM ABHD2 GRM5 FZD10 PDZD2

3.37e-0519021076c7e1086c0a274cd5527c3104106e372811c9905
ToppCellFetal_29-31_weeks-Immune-B_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HLA-DQB1 ACSM3 ALOX5 CARD11 IGLC2 IGLC3 IGLC6

3.37e-051902107424550418c1bd4eb070cf3c41cf09fa9d89aef37
ToppCellBL-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GABRP GCNT3 SLC16A9 SLC15A2 ASS1 ATP12A PDZD2

3.37e-051902107f2abe4bc28e934287e2dcd7b9399d5af78c5c8cf
ToppCellwk_20-22-Hematologic_Lymphocytic-B-Late_pre-B|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

HLA-DQB1 ACSM3 ALOX5 CARD11 IGLC2 IGLC3 IGLC6

3.48e-0519121072b05be1888cccd03a32341bcb1de4a899d4179fd
ToppCellCOVID-19-Myeloid-DC2|COVID-19 / Condition, Lineage and Cell class

HLA-DQB1 HLA-DQB2 CCND1 SH3BP4 ALOX5 P2RY12 P2RY6

3.48e-0519121071304ab7b5713f29f3966ffc020ea1b52e8e2f375
ToppCelltumor_Lung|World / Location, Cell class and cell subclass

CCL13 PLK3 STEAP4 CXCR6 SLC18A2 IGLC2 IGLC3

3.84e-0519421077e6b8a30f8d08252ad3f1df826d6f7c0ba997c2c
ToppCellCOVID_vent-Myeloid-Monocytic-Neutrophil|COVID_vent / Disease condition, Lineage, Cell class and subclass

TLR6 IL18RAP ALOX5 STEAP4 MTHFS TLR1 WDFY3

3.84e-051942107eb23b171e429165dd26a64377eae7fa2ce25f547
ToppCellproximal-3-Hematologic-IGSF21+_Dendritic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HLA-DQB1 HLA-DQB2 NAIP NPIPA1 P2RY12 P2RY6 CARD11

3.97e-0519521078592d0332bc82a91e173680cfd1afc5ee189b289
ToppCellproximal-Hematologic-IGSF21+_Dendritic|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HLA-DQB1 HLA-DQB2 NAIP NPIPA1 P2RY12 P2RY6 CARD11

3.97e-051952107c48ff83c48342875f06c6c9e7d5bc6084a992848
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRP CCND1 SLC16A9 STEAP4 SLC15A2 ASS1 ATP12A

3.97e-051952107ff9f6b38f41dc5660b746fe40ceaddfb2958acd3
ToppCellproximal-Hematologic-IGSF21+_Dendritic-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HLA-DQB1 HLA-DQB2 NAIP NPIPA1 P2RY12 P2RY6 CARD11

3.97e-051952107ae9d61011e95f7840cbb154738c79745fd29943e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM2 GPR83 SLC35F3 CACNA1B CACNA1E GRM5 CPNE4

3.97e-051952107ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRP CCND1 SLC16A9 STEAP4 SLC15A2 ASS1 ATP12A

3.97e-051952107460e12044905370797fd9774e99c3aedaebfe343
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRP CCND1 SLC16A9 STEAP4 SLC15A2 ASS1 ATP12A

4.10e-0519621071ff4b41817556a6e573f0737819a5cc24a7ef821
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GABRP GCNT3 CCND1 SLC16A9 STEAP4 ASS1 ATP12A

4.10e-051962107e819088a74d29e958371aa851ac9c74ec55367b7
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

GABRP GCNT3 CCND1 SLC16A9 STEAP4 ASS1 ATP12A

4.10e-051962107e675d661b6494ac3a85ba7ee5bdeaa98b8bbe957
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRP ABCA13 SLC16A9 STEAP4 SLC15A2 ASS1 ATP12A

4.10e-051962107c18874f37b90e6afacc562b2082b67ea8a7cb4a4
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GABRP GCNT3 CCND1 SLC16A9 STEAP4 ASS1 ATP12A

4.10e-051962107a4d05d85fbafa869df19bba3881020ea433d81fb
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GABRP GCNT3 CCND1 SLC16A9 STEAP4 ASS1 ATP12A

4.10e-05196210791a3c3091064f1f5a3bdc1dd5883fc24dce8ff05
ToppCellBronchial-NucSeq-Immune_Myeloid-Dendritic_cell-DC_2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DQB1 HLA-DQB2 NAIP ALOX5 P2RY12 P2RY6 TLR1

4.10e-0519621078862964090f9a679a548103bfbb12e91295aae62
ToppCelldistal-Hematologic-IGSF21+_Dendritic|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HLA-DQB1 HLA-DQB2 NAIP CCL13 LPAR5 P2RY12 P2RY6

4.24e-051972107a357ee2ba9100dfaeba9ecae8138a2776bb54b0b
ToppCelldistal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GABRP GCNT3 ABCA13 KCNK1 SLC15A2 ASS1 ATP12A

4.24e-051972107a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DQB1 RYR1 ALOX5 P2RY12 P2RY6 TLR1 POLQ

4.24e-0519721070a404b4494a2246d5a92299235056f0fda4d2b48
ToppCellwk_15-18-Hematologic-Myeloid-CX3CR1+_Mac|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HLA-DQB1 NAIP LPAR5 P2RY12 IFNGR1 P2RY6 TLR1

4.24e-051972107701334bc164e3b41132232f27574a87e9c3a5be5
ToppCellAT2_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

CCND1 KCNK1 TMEM164 STEAP4 ASS1 IGLC2 HAS3

4.24e-0519721078b5d4e1c33a57c899c51feb9a6f347232f8910a3
ToppCellMild_COVID-19-Epithelial-Basal/Club|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

GABRP GCNT3 CCND1 SLC16A9 STEAP4 ASS1 ATP12A

4.24e-0519721074cc5b778e1e2c6c149160fa147c172977c0fa8eb
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_CHIT1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SLC29A3 HLA-DQB2 TLR6 NCEH1 HEATR3 P2RY12 TLR1

4.37e-051982107243109377d62d20c69e9d1fedc252156e90cda1e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GABRP CCND1 INPP4B KCNK1 STEAP4 SLC15A2 ASS1

4.37e-051982107270cecff42b87b7e03f09dd9f99547b287b4598c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GABRP CCND1 INPP4B KCNK1 STEAP4 SLC15A2 ASS1

4.37e-0519821078b3f4effaaccf8777cde854d5d8a765962f7312b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PIWIL1 ATP9B MFSD4B LPAR5 STEAP4 IFNGR1

4.38e-0513521069f9d0787a2e99207a9caa88a85565189ab8b940a
ToppCellBiopsy_Other_PF-Epithelial-MUC5B+|Biopsy_Other_PF / Sample group, Lineage and Cell type

GABRP GCNT3 SLC16A9 STEAP4 SLC15A2 ASS1 ATP12A

4.52e-051992107afd0df242a93f176438309668a9487be1250d9ca
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DQB1 RYR1 ALOX5 LPAR5 P2RY12 TLR1 CARD11

4.52e-051992107744b63fba33b176ab7dde11646ccb313665505f7
ToppCellBiopsy_Control_(H.)-Epithelial-MUC5B+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

GABRP GCNT3 SLC16A9 STEAP4 SLC15A2 ASS1 ATP12A

4.52e-0519921074ab45996e6bca406c77895a5998982b8ab1cf210
ToppCellBiopsy_IPF-Epithelial-MUC5AC+_High|Biopsy_IPF / Sample group, Lineage and Cell type

GABRP GCNT3 SLC16A9 STEAP4 SLC15A2 ASS1 ATP12A

4.52e-05199210751cb306e36537a53968c55187bd87c83e1706187
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DQB1 NAIP RYR1 CCL13 ALOX5 P2RY6 TLR1

4.66e-052002107179afc4bee7a2fd85a3b5dadf32544a63807c164
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

INPP4B SH3BP4 STEAP4 OR8J1 SLC15A2 P2RY6 ATP12A

4.66e-052002107b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DQB1 HLA-DQB2 NAIP CCL13 ALOX5 LPAR5 P2RY6

4.66e-0520021074b4df0fe47498310d94448b8a289e58e4f5b5aa8
ToppCellParenchyma_COVID-19-Epithelial-TX-Club|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

GABRP GCNT3 ABCA13 CCND1 STEAP4 SLC15A2 ATP12A

4.66e-05200210785f946dd3831acf3488c87efba96689cc2667c3a
ToppCellBiopsy_IPF-Epithelial-MUC5B+|Biopsy_IPF / Sample group, Lineage and Cell type

GABRP GCNT3 SLC16A9 STEAP4 SLC15A2 ASS1 ATP12A

4.66e-052002107f0a6747f6d37ec6d261bd649ac678c39cca5e4c8
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GABRP GCNT3 ABCA13 CCND1 STEAP4 SLC15A2 ATP12A

4.66e-0520021078a44a4f7ea9358f2194a490e79601c98ff7fdcb0
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

GABRP GCNT3 ABCA13 CCND1 STEAP4 SLC15A2 ATP12A

4.66e-05200210730d428510c68da96c7c8cfd472f449ebb9631132
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

GABRP GCNT3 KCNK1 DNAH9 LRRC9 TTLL6 ATP12A

4.66e-05200210772c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

GABRP GCNT3 KCNK1 DNAH9 LRRC9 TTLL6 ATP12A

4.66e-052002107da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellSepsis-ICU-NoSEP-Myeloid-cDC1|ICU-NoSEP / Disease, condition lineage and cell class

HLA-DQB1 CCND1 SH3BP4 C2orf81 P2RY6 MCUR1 TSPAN6

4.66e-052002107511e642575182fb678df6791ee6539b0ced3eb17
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

INPP4B PLCL1 CACNA1B GPR35 CXCR6 CARD11

7.04e-0514721061ecd7c084e73eb6fae1ab1f9aae17115d3d62cbd
ToppCellfacs-Marrow-B-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC29A3 CCR9 LRRC69 CCND1 NPBWR1 CARD11

7.04e-0514721069d7e965fe61bd7b31e09c4b2129a5a98c36f4811
ToppCellfacs-Marrow-B-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC29A3 CCR9 LRRC69 CCND1 NPBWR1 CARD11

7.04e-05147210638552953ff65a0fc20bee6ef57dc5885306ad18b
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCR9 IL18RAP RNASEH2A SLC6A13 CXCR6 CARD11

7.59e-051492106efa30fcd9370f98eb7445f295eb4d0305ff455c3
ToppCellLPS-antiTNF-Hematopoietic_Mast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

INPP4B CACNA1B GPR35 CXCR6 SLC18A2 CARD11

7.59e-0514921061527cdd98a2734cbf8ce4c6170557280b71c55cb
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

INPP4B CACNA1B GPR35 CXCR6 SLC18A2 CARD11

7.59e-05149210659aa1f2a5cbeba64c4529fb05f544db17fd8b188
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP|Cerebellum / BrainAtlas - Mouse McCarroll V32

BRIP1 CCR9 SLC13A4 SLC6A13 STEAP3 FZD10

7.59e-0514921063980fa4f1986a2f164a1826ea043fb71f1d756cd
Diseasecholelithiasis

SH3BP4 LDHD UGT1A5 UGT1A4 UGT1A3 MUSK VPS13B

2.44e-06882017EFO_0004799
DiseaseDown syndrome (implicated_via_orthology)

DSCAML1 DOP1B DSCAM RCAN3

2.69e-06152014DOID:14250 (implicated_via_orthology)
Diseaseurate measurement, spine bone mineral density

RIC1 UGT1A5 ADGRL1 UGT1A4 UGT1A3 CPNE4

2.79e-06582016EFO_0004531, EFO_0007701
DiseaseRS-warfarin measurement

AADACL4 TMEM215 DSCAML1 UNC5A DNAH9 PHIP NPBWR1 P2RY6

2.87e-061282018EFO_0803325
DiseaseX-11793--oxidized bilirubin measurement

UGT1A5 UGT1A4 UGT1A3

1.70e-0582013EFO_0021260
DiseaseSuccinimide measurement

UGT1A5 UGT1A4 UGT1A3

1.70e-0582013EFO_0022118
DiseaseX-11530 measurement

UGT1A5 UGT1A4 UGT1A3

1.70e-0582013EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A5 UGT1A4 UGT1A3

1.70e-0582013EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A5 UGT1A4 UGT1A3

1.70e-0582013EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A5 UGT1A4 UGT1A3

1.70e-0582013EFO_0800696
DiseaseX-10458 measurement

UGT1A5 UGT1A4 UGT1A3

1.70e-0582013EFO_0800692
DiseaseX-24849 measurement

UGT1A5 UGT1A4 UGT1A3

1.70e-0582013EFO_0800909
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A5 UGT1A4 UGT1A3

1.70e-0582013EFO_0802740
DiseaseX-16946 measurement

UGT1A5 UGT1A4 UGT1A3

1.70e-0582013EFO_0800766
Diseaseasthma, allergic disease

EXD1 HLA-DQB1 HLA-DQB2 TLR6 SH3BP4 TLR1

1.70e-05792016MONDO_0004979, MONDO_0005271
DiseaseX-11442 measurement

UGT1A5 UGT1A4 UGT1A3

2.54e-0592013EFO_0021236
DiseaseX-11441 measurement

UGT1A5 UGT1A4 UGT1A3

2.54e-0592013EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A5 UGT1A4 UGT1A3

2.54e-0592013EFO_0004739
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A5 UGT1A4 UGT1A3

2.54e-0592013EFO_0801037
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A5 UGT1A4 UGT1A3

2.54e-0592013EFO_0801036
DiseaseX-11880 measurement

UGT1A5 UGT1A4 UGT1A3

2.54e-0592013EFO_0800698
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A5 UGT1A4 UGT1A3

2.54e-0592013EFO_0020691
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A5 UGT1A4 UGT1A3

2.54e-0592013EFO_0802127
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A5 UGT1A4 UGT1A3

2.54e-0592013EFO_0004570, GO_0009410
Diseasebilirubin measurement, response to tenofovir

UGT1A5 UGT1A4 UGT1A3

3.61e-05102013EFO_0004570, EFO_0009279
DiseaseX-21448 measurement

UGT1A5 UGT1A4 UGT1A3

3.61e-05102013EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A5 UGT1A4 UGT1A3

3.61e-05102013EFO_0802185
DiseaseX-23974 measurement

UGT1A5 UGT1A4 UGT1A3

3.61e-05102013EFO_0800867
Diseasetuberculosis (is_implicated_in)

HLA-DQB1 TLR6 IFNGR1 TLR1

3.76e-05282014DOID:399 (is_implicated_in)
Diseasehistidine betaine (hercynine) measurement

UGT1A5 UGT1A4 UGT1A3

4.94e-05112013EFO_0800972
DiseaseX-21796 measurement

UGT1A5 UGT1A4 UGT1A3

4.94e-05112013EFO_0800825
Diseaseinsomnia, bilirubin measurement

UGT1A5 UGT1A4 UGT1A3

4.94e-05112013EFO_0004570, EFO_0004698
Diseasealdosterone measurement

UGT1A5 UGT1A4 UGT1A3

4.94e-05112013EFO_0010219
Diseasep-cresol glucuronide measurement

UGT1A5 UGT1A4 UGT1A3

6.55e-05122013EFO_0800079
Diseasebiliverdin measurement

UGT1A5 UGT1A4 UGT1A3

6.55e-05122013EFO_0021033
Diseasephosphatidylcholine 40:7 measurement

NPIPA1 NPIPA2 MUSK

8.47e-05132013EFO_0021477
Diseaseretinol dehydrogenase 16 measurement

UGT1A5 UGT1A4 UGT1A3

8.47e-05132013EFO_0802007
Diseasegallstones

SH3BP4 LDHD UGT1A5 UGT1A4 UGT1A3 MUSK

9.97e-051082016EFO_0004210
Diseaseasthma (is_implicated_in)

HLA-DQB1 TLR6 ALOX5 P2RY12 EDNRB IFNGR1 TLR1

1.05e-041572017DOID:2841 (is_implicated_in)
DiseaseCohen syndrome (implicated_via_orthology)

VPS13A VPS13B

1.38e-0432012DOID:0111590 (implicated_via_orthology)
Diseasefamilial hemiplegic migraine 1 (implicated_via_orthology)

CACNA1B CACNA1E

1.38e-0432012DOID:0111181 (implicated_via_orthology)
Diseasejuvenile idiopathic arthritis

ABCA13 HLA-DQB1 HLA-DQB2 SLC13A4 ATP8B2

1.54e-04742015EFO_0002609
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A5 UGT1A4 UGT1A3

1.97e-04172013EFO_0004611, EFO_0007800
DiseaseX-21441 measurement

SLCO1B3 UGT1A5 UGT1A4

1.97e-04172013EFO_0800814
Diseaseangiopoietin-related protein 1 measurement

UGT1A5 UGT1A4 UGT1A3

2.36e-04182013EFO_0801382
Diseasemigraine (implicated_via_orthology)

CACNA1B CACNA1E

2.75e-0442012DOID:6364 (implicated_via_orthology)
Diseaseunipolar depression, smoking behaviour measurement

OR5AK2 OR5AK3P

2.75e-0442012EFO_0003761, EFO_0005671
DiseaseTreacher Collins syndrome

POLR1B TCOF1

2.75e-0442012cv:C0242387
Diseasetype 1 diabetes mellitus, latent autoimmune diabetes in adults

HLA-DQB1 HLA-DQB2

2.75e-0442012EFO_0009706, MONDO_0005147
Diseaseskin hydration measurement

PIWIL1 PKD1L1 FZD10

3.78e-04212013EFO_0009586
Diseasetissue factor measurement

UGT1A5 UGT1A4 UGT1A3

3.78e-04212013EFO_0010623
Diseaseresponse to trauma exposure

PIWIL1 SLC35F3 KCNK1 OR5V1

4.07e-04512014EFO_0008483
DiseaseMalignant neoplasm of breast

GABRP BRIP1 CATSPERE LRRC37A2 CCND1 DTX3L INPP4B LRRC37A RIC8A DNAH9 NPBWR1 VPS39 PHF7 THOC5 EDNRB OR12D3 G6PC1 VPS13B

4.26e-04107420118C0006142
Diseaseasthma exacerbation measurement

HLA-DQB1 HLA-DQB2 IL18RAP TENM2 GRM5

4.46e-04932015EFO_0007614
Diseasechoreatic disease (is_implicated_in)

HLA-DQB1 VPS13A

4.56e-0452012DOID:12859 (is_implicated_in)
Diseasenarcolepsy-cataplexy syndrome, age at onset

HLA-DQB1 HLA-DQB2

4.56e-0452012EFO_0004847, MONDO_0016158
DiseaseMandibulofacial dysostosis

POLR1B TCOF1

4.56e-0452012cv:CN004722
DiseaseHPV seropositivity

HLA-DQB1 HLA-DQB2

4.56e-0452012EFO_0004510
Diseaselevel of coiled-coil domain-containing protein 134 in blood serum

HLA-DQB1 HLA-DQB2

4.56e-0452012OBA_2044258
DiseaseVaricella zoster virus seropositivity

HLA-DQB1 HLA-DQB2

4.56e-0452012EFO_0009340
Diseasedeoxycarnitine measurement

SLC16A9 SLC6A13

6.80e-0462012EFO_0800259
Diseaseantibody measurement, Epstein-Barr virus infection

HLA-DQB1 HLA-DQB2

6.80e-0462012EFO_0000769, EFO_0004556
Diseasepneumocystosis (biomarker_via_orthology)

HLA-DQB1 HLA-DQB2

6.80e-0462012DOID:11339 (biomarker_via_orthology)
DiseaseTreacher Collins syndrome (implicated_via_orthology)

POLR1B TCOF1

6.80e-0462012DOID:2908 (implicated_via_orthology)
Diseasepemphigus

HLA-DQB1 HLA-DQB2

6.80e-0462012EFO_1000749
DiseaseParkinson's disease (implicated_via_orthology)

ADCY5 VPS13A NPBWR1 OPRM1 SLC18A2 SLC17A8

7.47e-041572016DOID:14330 (implicated_via_orthology)
Diseaseretinal vasculature measurement

DSCAML1 ACTL6B PLCL1 DNAH9 NPBWR1 ABHD2 FRY POLR3B CPNE4 HAS3 PDZD2

8.93e-0451720111EFO_0010554
Diseaseantinuclear antibody measurement

HLA-DQB1 HLA-DQB2

9.48e-0472012EFO_0005949
DiseaseAnti-Helicobacter pylori IgG measurement

HLA-DQB1 HLA-DQB2

9.48e-0472012EFO_0009352
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1B CACNA1E

9.48e-0472012DOID:0050951 (implicated_via_orthology)
Diseaselevel of Phosphatidylcholine (16:0_22:6) in blood serum

CPNE4 MUSK

9.48e-0472012OBA_2045080
Diseasexanthurenate measurement

UGT1A5 UGT1A4 UGT1A3

9.99e-04292013EFO_0010551
Diseasepulmonary tuberculosis

HLA-DQB1 HLA-DQB2 CCNY

9.99e-04292013EFO_1000049
DiseaseIntellectual Disability

ACTL6B MED23 PHIP CACNA1B CACNA1E RNASEH2A FRY POLR3B ASS1 ATIC

1.05e-0344720110C3714756
Diseasebrain aneurysm

SLC35F3 DSCAM CARD11 CPNE4 PDZD2

1.08e-031132015EFO_0003870
Diseaseresponse to dolutegravir

UGT1A5 UGT1A4 UGT1A3

1.10e-03302013EFO_0600017
DiseaseIgA glomerulonephritis (is_implicated_in)

HLA-DQB1 ACSM3 TLR1

1.10e-03302013DOID:2986 (is_implicated_in)
DiseaseDrug habituation

PIWIL1 TENM2 DSCAM GRM5 OPRM1

1.17e-031152015C0013170
DiseaseDrug abuse

PIWIL1 TENM2 DSCAM GRM5 OPRM1

1.17e-031152015C0013146
DiseasePrescription Drug Abuse

PIWIL1 TENM2 DSCAM GRM5 OPRM1

1.17e-031152015C4316881
DiseaseSubstance-Related Disorders

PIWIL1 TENM2 DSCAM GRM5 OPRM1

1.17e-031152015C0236969
DiseaseDrug Use Disorders

PIWIL1 TENM2 DSCAM GRM5 OPRM1

1.17e-031152015C0013222
DiseaseDrug Dependence

PIWIL1 TENM2 DSCAM GRM5 OPRM1

1.17e-031152015C1510472
DiseaseSubstance Dependence

PIWIL1 TENM2 DSCAM GRM5 OPRM1

1.17e-031152015C0038580
DiseaseSubstance Use Disorders

PIWIL1 TENM2 DSCAM GRM5 OPRM1

1.17e-031152015C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

PIWIL1 TENM2 DSCAM GRM5 OPRM1

1.17e-031152015C0029231
DiseaseSubstance abuse problem

PIWIL1 TENM2 DSCAM GRM5 OPRM1

1.21e-031162015C0740858
Diseasecutaneous mastocytosis

ABCA2 DYNC2I1 POLQ

1.22e-03312013EFO_1000886
DiseaseIgG index

HLA-DQB1 HLA-DQB2

1.26e-0382012EFO_0006929
Diseaseaspergillosis (is_implicated_in)

TLR6 TLR1

1.26e-0382012DOID:13564 (is_implicated_in)
DiseasePAX-interacting protein 1 measurement

HLA-DQB1 HLA-DQB2

1.26e-0382012EFO_0801868
Disease1-linoleoyl-2-arachidonoyl-GPC (18:2/20:4n6) measurement

ABHD2 MUSK

1.26e-0382012EFO_0800450
Diseasesoluble CD163 measurement

HLA-DQB1 HLA-DQB2

1.26e-0382012EFO_0020072
Diseasegdnf family receptor alpha-1 measurement

HLA-DQB1 HLA-DQB2

1.26e-0382012EFO_0020400
Diseaseasthma, seasonal allergic rhinitis

HLA-DQB1 HLA-DQB2 TLR1

1.34e-03322013EFO_0003956, MONDO_0004979
Diseasecreatinine measurement

BRIP1 PSMD1 ATP9B RYR1 ACSM3 SLC35F3 MED23 OR5V1 DSCAM PHF7 SPATA20 SLC6A13 FRY MUSK HCRTR2 TDRD12

1.37e-0399520116EFO_0004518
Diseasesleep apnea measurement, obstructive sleep apnea

GPR83 SLC35F3 KCNK1

1.46e-03332013EFO_0003918, EFO_0007817
Diseaseasthma, Eczema, allergic rhinitis

HLA-DQB1 HLA-DQB2 PLCL1 SLC15A2 TLR1

1.46e-031212015EFO_0005854, HP_0000964, MONDO_0004979
Diseasezinc fingers and homeoboxes protein 3 measurement

HLA-DQB1 HLA-DQB2

1.61e-0392012EFO_0803299
DiseaseEpstein Barr virus nuclear antigen 1 IgG measurement

HLA-DQB1 HLA-DQB2

1.61e-0392012EFO_0007790

Protein segments in the cluster

PeptideGeneStartEntry
TDPVNLCAAVLAKYL

UGT1A3

151

P35503
LCAAVLAKYLSIPTV

UGT1A3

156

P35503
KFLAVVFCLIGYVPS

ABCA5

1101

Q8WWZ7
ILEIKAFPFYNTVCI

NAIP

596

Q13075
LHLTTFCLQYKPTVI

CCNT2

181

O60583
IFKLCSICLYLPQEQ

C6orf62

196

Q9GZU0
ACLNPVLYAFVSLKF

CXCR6

281

O00574
LVLVQFRPSEYSKAC

CATSPERE

676

Q5SY80
VQSFKALPYVCLLIA

CACNA1E

1601

Q15878
CQKSFLALVNLLSYP

TBC1D32

786

Q96NH3
LLKLATCFEVASPEY

ALS2

851

Q96Q42
YVITTSRCPQKAVIF

CCL13

51

Q99616
LYVIVRCLNLKSPTA

ABHD2

26

P08910
YNIPAFFLCKTAVLT

ACTL6B

141

O94805
KTQYEIACPIFAGLL

ADGRL1

916

O94910
LLLVFLIYHQTCKVP

ALG3

136

Q92685
YILAKLSTCQFALPL

GVINP1

986

Q7Z2Y8
PIYILVQLLSAFCAS

AQP10

101

Q96PS8
STPFCLKLYQEILQL

ABCA13

3286

Q86UQ4
PCSLKIVNAVVSYIK

AADACL4

391

Q5VUY2
KYINTVVSCLVFVLG

EDNRB

101

P24530
SVSYFKCVQKEVLPS

CCND1

41

P24385
VSQPNLKYTIKCVAL

CCNY

111

Q8ND76
VSVIYSCVKLFPSPL

ADCY5

806

O95622
LNYLGTVSLTKCVLP

DHRS7

161

Q9Y394
TFVQSFKALPYVCLL

CACNA1B

1591

Q00975
PNLRTTVKCVTLAIY

CCNYL1

136

Q8N7R7
VRFELSCYSLAPQIK

ASS1

126

P00966
YLKKFLSTPQAGCLV

ADAMTS18

481

Q8TE60
NCIKTSKYNILTFLP

ATP8B2

51

P98198
VINYDLLCAVSKLGP

RCAN3

166

Q9UKA8
LLFQFIKSVLTVNPC

RIC1

401

Q4ADV7
SYLCVSFLKTIFPSQ

NPIPA1

61

Q9UND3
LIKAVPVNCTLYICD

KBTBD3

501

Q8NAB2
LVPLQVLICSYKCFT

LRRC69

321

Q6ZNQ3
SFSGLIYLPNVKVLC

LRRC9

1131

Q6ZRR7
VTQLPYNIVKFCRAI

ACKR4

251

Q9NPB9
DLSFSCKYKVTVQPI

ANOS1

491

P23352
LCAIPFAKSYVTLAL

SLC16A9

386

Q7RTY1
VKPYTLALAFKEQIC

MTHFS

166

P49914
TVLYKDTVVFRVAPC

PADI6

291

Q6TGC4
ICSPLLYSVIISNKA

OR8G1

126

Q15617
ISNKACFSLILGVYI

OR8G1

136

Q15617
LLPLLKLSCSSIYVN

OR8G1

181

Q15617
SIYVNKLLILCVGAF

OR8G1

191

Q15617
ICSPLLYSIIISNKA

OR8G5

161

Q8NG78
ISNKACFSLILVVYV

OR8G5

171

Q8NG78
PFGTILCKIVISIDY

OPRM1

136

P35372
TLKLILIKFCYFQEP

IL18RAP

506

O95256
LPFLKFINLSCNVIT

LRRC37A3

936

O60309
ILSCTFYAFKTRNVP

GRM5

751

P41594
NIKYLAGSIFTCLTV

MCUR1

336

Q96AQ8
LPFLKFINLSCNVIT

LRRC37A2

936

A6NM11
LPFLKFINLSCNVIT

LRRC37A

936

A6NMS7
VIFLLCFVPYNSTLA

LPAR5

241

Q9H1C0
NKFELNTYPLTVECL

GCNT2

366

Q8N0V5
IAYSLTKNIAELCPF

ATP12A

791

P54707
TKNIAELCPFLIYII

ATP12A

796

P54707
YFLVISCSQFVPALK

ATP9B

161

O43861
IPQSELILYLSACKF

DOP1B

2141

Q9Y3R5
VCGFIIKLQTSLYDP

INPP4B

636

O15327
TLYGPLLNAFLCIKE

KIAA1109

736

Q2LD37
KAFCIIYSVIGIPFT

KCNK1

131

O00180
YLPNCITTLQESLIK

EXD1

196

Q8NHP7
KSFVPLLDSKYVLCV

DYNC2I1

666

Q8WVS4
LVCSVTDFYPAQIKV

HLA-DQB2

146

P05538
PFVIYAAKVFLRCIN

IFNAR1

451

P17181
AVYCPVIAAVFIVLK

PCNX1

61

Q96RV3
IVLLLKAFPYCGSVV

OR51M1

171

Q9H341
VTCSILAYLPFKLEK

PCDHGA10

386

Q9Y5H3
AAICPASAKVLSLKY

PDZD2

1621

O15018
QAVLQLLPKTYILTC

NCEH1

331

Q6PIU2
CLLPAYFAVTEIRKL

MED23

176

Q9ULK4
PSVFTVCVSYLQKRL

KLHL41

116

O60662
SYLCVSFLKTIFPSQ

NPIPA3

61

F8WFD2
FIDACYSSVNTPKLI

OR4C13

66

Q8NGP0
FTAVPLSIIVISYCL

OR2C1

206

O95371
LCTRDYKITQVLFPL

P2RY12

16

Q9H244
LLAKLADYVVPGCQT

HECTD4

1476

Q9Y4D8
YLCVSFLKTIFPSQN

NPIPA2

81

E9PIF3
YLPLAVVVFCSLKVV

GPR35

181

Q9HC97
SLTCQVFGYIISVLK

GPR52

111

Q9Y2T5
FPLNCYVLLLSSKVI

GPR83

306

Q9NYM4
YCLFQNEKLLPETVT

C17orf75

126

Q9HAS0
KQVFELLAALCIYSP

INF2

141

Q27J81
LYLVPFCKTAILLTV

MFSD4B

76

Q5TF39
LAFVDICYTSAITPK

OR5AK3P

66

Q8NH89
YSSVTLPKLLVNLVC

OR12D3

71

Q9UGF7
IKFFPNVYALLKVLC

THAP12

671

O43422
TVSQGILCFLPSYKL

BRIP1

686

Q9BX63
ICNPLRYSVILSKVL

OR5V1

126

Q9UGF6
LAFVDICYTSAITPK

OR5AK2

66

Q8NH90
SLLEKYPCSKFIIAI

PSMG1

61

O95456
LCKVIPYLQTVSVSV

HCRTR2

126

O43614
CYLPISILNVLKRVF

HCRTR2

316

O43614
VSYFNIVLSILKICS

OR8J1

216

Q8NGP2
VNALTGFVLIPLACY

FZD10

391

Q9ULW2
KIGVFSVLYTVPATC

FZD4

436

Q9ULV1
LLVCSVTDFYPAQIK

HLA-DQB1

146

P01920
CLEIVLKYLSRFPTN

HEATR3

186

Q7Z4Q2
QVIVDYLCKLSSLPA

FASTKD5

161

Q7L8L6
ANKATLVCLISDFYP

IGLC1

21

P0CG04
PVLKLLVAAAKSQYC

EXT1

496

Q16394
ALQKVVVPIYCTSFL

CHERP

236

Q8IWX8
LFSKEQRAYITTLCP

DTX3L

146

Q8TDB6
YNKALELTEACPFVI

EFCAB7

491

A8K855
VAVFKCLIPSSVQEY

DSCAML1

141

Q8TD84
VFYVLSFCKSAVVPL

G6PC1

321

P35575
DFIQSYKILLLSCGI

POLQ

1966

O75417
VIRTCINPVYSKLFT

CPNE4

66

Q96A23
ANKATLVCLISDFYP

IGLC2

21

P0DOY2
NRYSKLNCLVAPTLF

LDHD

311

Q86WU2
AAALCIPEILYSQIK

CCR9

176

P51686
GAVLYKACSVIFPLI

SQLE

551

Q14534
ANKATLVCLISDFYP

IGLC3

21

P0DOY3
VKAIISCFPNVFIAS

GCNT3

176

O95395
ANKATLVCLISDFYP

IGLC6

21

P0CF74
VFLCYKKSVPASNAI

DENND4C

191

Q5VZ89
VVNSYLKSCFLIFPN

ABCA2

1936

Q9BZC7
LRKTYAPIFEVNLCL

DNAH14

526

Q0VDD8
LSAKTCSLFLPNYVQ

KNDC1

1516

Q76NI1
SAFKVYLTQQCIPFT

C2orf81

71

A6NN90
VQLVGIIKATYACFL

HAS3

416

O00219
VLQLFCSSPKAALRY

COPG1

291

Q9Y678
RANLTILFDKYLPTC

DNAH9

2311

Q9NYC9
LYPLVTCLLCVSQKQ

FRY

361

Q5TBA9
LILSDVYPFSCKAVA

FDXACB1

156

Q9BRP7
IFLDANVKESYCPLV

HPS1

351

Q92902
FVSLLETNKPYLVNC

DHX34

881

Q14147
VLCYAASVNKKTIPS

SLC22A14

336

Q9Y267
YFKNTTLLLVGVICV

SLC13A4

81

Q9UKG4
IPLFDFVIYRLVSKC

SLC15A2

356

Q16348
TNHCLYFLSTPAKVL

RYR1

3011

P21817
AYFKVCSQSLLPIIN

CFAP47

986

Q6ZTR5
QIYKVLVLSRVVPYC

CFAP47

1706

Q6ZTR5
LFTLKCVYLPGIQNT

PKD1L1

2621

Q8TDX9
INYSLCLKPDLLDFT

NPEPPS

61

P55786
KSNIYPIVLFIRVCE

CARD11

1066

Q9BXL7
LPNTNCFIKAIDVYL

GABRP

296

O00591
LSLVFICFYIKKINP

IFNGR1

261

P15260
TTCVYRENFKQLLLP

P2RY6

16

Q15077
YTLVLGFAIPVSTIC

NPBWR1

206

P48145
TPLLNSIIYTLCNKE

OR10G6

301

Q8NH81
LSFADICYTTVIVPK

OR1L3

66

Q8NH93
SYLCVSFLKTIFPSQ

NPIPA7

61

E9PJI5
SYLCVSFLKTIFPSQ

NPIPA8

61

P0DM63
AYLCTITGFILPEKI

RPP40

276

O75818
TLVNYEVPQFLDCLK

PIWIL1

711

Q96J94
AVFKCIIPSSVEAYI

DSCAM

141

O60469
LIYPAICTNIESLNK

SLC29A3

321

Q9BZD2
LPTIFCNIVLKTYVP

PLCB4

811

Q15147
IAIKDYCPTNFTTLK

SH3BP4

61

Q9P0V3
LYPVVSAASICAKVA

RNASEH2A

171

O75792
NPSKFLIYTCLLLFS

TMEM185B

11

Q9H7F4
QKCFLAQPVTLLDIY

TCOF1

36

Q13428
TFRIQLPCLSSYIKF

FER1L5

376

A0AVI2
KLTVFTVLCEQYQPS

GET4

251

Q7L5D6
CTLQFLAAPICLLYK

ALOX5

301

P09917
SYLCVSFLKTIFPSQ

NPIPA5

61

E9PKD4
SVHYFCLILSSKLPQ

PHF7

56

Q9BWX1
FCLICNYLSKIIPAL

RFC5

151

P40937
LPVLTVLQTGACYKS

TDRD12

471

Q587J7
SYIKLGCLQFVFSIT

PHF12

951

Q96QT6
LAYTPTCVIGLNKDL

PSMD1

781

Q99460
CQVPGIDYSLSKLAI

TENM2

1456

Q9NT68
LAFVDLCYSSAITPK

OR8U3

66

Q8NH85
YRSFCKPQELLSLII

SOS1

631

Q07889
CVPFFGIYLTNILKT

SOS1

926

Q07889
LFVLCSESVPRFIKY

RIC8A

396

Q9NPQ8
LSFVDFCYSSIIVPK

OR5L2

66

Q8NGL0
ILFITCIPIILYFTK

SLC35F3

276

Q8IY50
CIEKSYKSIFVLSPN

TLR1

686

Q15399
ILQTLSKYPITVFCS

ACSM3

311

Q53FZ2
LAASSPYFCDQVLLK

ZBTB43

51

O43298
CYQLPALLAKGITIV

RECQL5

61

O94762
CIKQVHYTLPASLSL

PLK3

271

Q9H4B4
CTRPEVYFLLVQISK

PLCL1

311

Q15111
NKFAFVASEYPLILC

PLCL1

476

Q15111
YLVNPTCQVLVKDFT

ZER1

156

Q7Z7L7
KGKITTVLQPCDLFY

VPS13A

1616

Q96RL7
VVFSLNYIPCKELIS

WDFY3

451

Q8IZQ1
SYRPLCVLTFKLNIF

TMTC1

91

Q8IUR5
IFFVPQDSIIVCSYK

TMEM215

196

Q68D42
LLHFIKDQTCYNIIP

PHIP

1256

Q8WWQ0
EYLASLFPTCTVVKA

STEAP3

131

Q658P3
ENKILPFQYVLCAAT

TFCP2

61

Q12800
FATKTVIYLLNPCHL

TMEM164

111

Q5U3C3
VAILSFKLPYCQIAT

WDHD1

706

O75717
CVHSVYIPNKVLILA

SPATA20

721

Q8TB22
PAVCTATFLFSLIKY

SLC6A13

501

Q9NSD5
FQLLYFPLICESKSV

SLCO1B3

421

Q9NPD5
ICAVALPFVASSYVI

SLC17A2

361

O00624
VLQYALEFASSKPVC

USP25

451

Q9UHP3
LCAAVLAKYLSIPAV

UGT1A5

156

P35504
CITFPTEYVKTQLQL

SLC25A1

41

P53007
FVQSKLGYLTLILCT

STEAP4

381

Q687X5
QVCSLVLYPIKFIET

TMEM47

126

Q9BQJ4
KYITALQKFLLPSDC

USP50

76

Q70EL3
KPVITCFKSVLLIYT

TSPAN6

11

O43657
VSSLRIPYACKLLFQ

POLR3B

1101

Q9NW08
LLDAVCLVPNKSLTY

TEX30

16

Q5JUR7
IRVVACNLYPFVKTV

ATIC

96

P31939
ICQLYISKPFIIDGF

TTLL6

201

Q8N841
CIEKSYKSIFVLSPN

TLR6

691

Q9Y2C9
VLLVCKAVPATQIFF

UNC5A

61

Q6ZN44
SLQKFPILVVCYTNH

ZNFX1

646

Q9P2E3
LLAQCVVYFARAPKS

WRNIP1

576

Q96S55
YPDPIAQKTCFIILS

XPOT

836

O43592
FSIYTLLGKQVTLCL

VPS13B

1161

Q7Z7G8
FKPQQLVSDICTIYL

UBE4A

906

Q14139
DCQYLFPAKVVSRLV

THOC5

506

Q13769
VTQFVYTASIPALLC

POLR1B

521

Q9H9Y6
SILCIPFAKNIYGLI

SLC18A2

371

Q05940
FNQSLYLVSCLKLLP

WDR87

626

Q6ZQQ6
NRVIFFYLSCVPKTQ

ZFC3H1

1841

O60293
AYCFATLTSLPQILV

HIVEP1

1646

P15822
KCVNVFTQKPLLSIY

ZNF81

306

P51508
YIPFLQLNCDLRKTS

TMEM39B

201

Q9GZU3
FTSLPVYAIIVANFC

SLC17A8

311

Q8NDX2
KCYLHTNVALVAPLL

VPS39

466

Q96JC1
LCGAVLAKYLSIPAV

UGT1A4

156

P22310
QLFITKPGLYTCIAT

MUSK

271

O15146