Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionneurexin family protein binding

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

2.31e-08161145GO:0042043
GeneOntologyMolecularFunctiondisaccharide binding

LGALS9C LGALS9B LGALS9

6.24e-0671143GO:0048030
GeneOntologyMolecularFunctiongalactoside binding

LGALS9C LGALS9B LGALS9

1.48e-0591143GO:0016936
GeneOntologyMolecularFunctionoligosaccharide binding

LGALS9C LGALS9B LGALS9

1.92e-04201143GO:0070492
GeneOntologyMolecularFunctionscaffold protein binding

NLGN4Y NLGN1 RYR2 NLGN3 NLGN4X

1.93e-04931145GO:0097110
GeneOntologyMolecularFunctionceramide 1-phosphate binding

PLEKHA8P1 PLA2G4A

6.66e-0471142GO:1902387
GeneOntologyBiologicalProcesspresynaptic membrane assembly

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

1.16e-09101145GO:0097105
GeneOntologyBiologicalProcesspostsynaptic membrane assembly

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

2.12e-09111145GO:0097104
GeneOntologyBiologicalProcesspresynaptic membrane organization

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

5.87e-09131145GO:0097090
GeneOntologyBiologicalProcessneuron cell-cell adhesion

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

1.96e-08161145GO:0007158
GeneOntologyBiologicalProcessnegative regulation of natural killer cell degranulation

LGALS9C LGALS9B LGALS9

6.55e-0741143GO:0043322
GeneOntologyBiologicalProcessregulation of natural killer cell differentiation

LGALS9C LGALS9B ZBTB1 LGALS9

4.93e-06211144GO:0032823
GeneOntologyBiologicalProcessregulation of macrophage activation

LGALS9C LGALS9B MYO18A CST7 LGALS9 PLA2G4A

5.78e-06811146GO:0043030
GeneOntologyBiologicalProcessreceptor clustering

LGALS9C LGALS9B NLGN1 LGALS9 WDR19 NLGN2

6.67e-06831146GO:0043113
GeneOntologyBiologicalProcesspositive regulation of protein localization to synapse

NLGN1 NLGN3 NLGN2

9.02e-0681143GO:1902474
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle clustering

NLGN1 NLGN3 NLGN2

9.02e-0681143GO:2000809
GeneOntologyBiologicalProcessregulation of natural killer cell degranulation

LGALS9C LGALS9B LGALS9

9.02e-0681143GO:0043321
GeneOntologyBiologicalProcessregulation of defense response to bacterium

LGALS9C LGALS9B LGALS9 SPINK5

1.20e-05261144GO:1900424
GeneOntologyBiologicalProcesspostsynapse assembly

NLGN4Y DOCK10 NLGN1 NLGN3 NLGN4X NLGN2

1.29e-05931146GO:0099068
GeneOntologyBiologicalProcessterminal button organization

NLGN1 NLGN3 NLGN2

1.35e-0591143GO:0072553
GeneOntologyBiologicalProcesspostsynaptic membrane organization

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

1.44e-05561145GO:0001941
GeneOntologyBiologicalProcesspresynapse assembly

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

2.02e-05601145GO:0099054
GeneOntologyBiologicalProcessmembrane assembly

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

2.78e-05641145GO:0071709
GeneOntologyBiologicalProcessmodulation of excitatory postsynaptic potential

NLGN1 NLGN3 NLGN4X NETO1 NLGN2

2.99e-05651145GO:0098815
GeneOntologyBiologicalProcessregulation of synaptic vesicle clustering

NLGN1 NLGN3 NLGN2

3.49e-05121143GO:2000807
GeneOntologyBiologicalProcessmembrane biogenesis

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

5.26e-05731145GO:0044091
GeneOntologyBiologicalProcesspresynapse organization

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

5.26e-05731145GO:0099172
GeneOntologyBiologicalProcesssocial behavior

NLGN4Y NLGN3 NLGN4X NLGN2 PCM1

5.61e-05741145GO:0035176
GeneOntologyBiologicalProcessnatural killer cell differentiation

LGALS9C LGALS9B ZBTB1 LGALS9

5.65e-05381144GO:0001779
GeneOntologyBiologicalProcessregulation of respiratory gaseous exchange by nervous system process

NLGN1 NLGN3 NLGN2

5.73e-05141143GO:0002087
GeneOntologyBiologicalProcessbiological process involved in intraspecies interaction between organisms

NLGN4Y NLGN3 NLGN4X NLGN2 PCM1

6.38e-05761145GO:0051703
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

7.13e-05151143GO:2000562
GeneOntologyBiologicalProcessnegative regulation of natural killer cell activation

LGALS9C LGALS9B LGALS9

7.13e-05151143GO:0032815
GeneOntologyBiologicalProcesspositive regulation of macrophage activation

LGALS9C LGALS9B LGALS9 PLA2G4A

8.42e-05421144GO:0043032
GeneOntologyBiologicalProcessterritorial aggressive behavior

NLGN4Y NLGN4X

9.05e-0531142GO:0002124
GeneOntologyBiologicalProcesspositive regulation of excitatory postsynaptic potential

NLGN1 NLGN3 NETO1 NLGN2

9.25e-05431144GO:2000463
GeneOntologyBiologicalProcessregulation of respiratory system process

NLGN1 NLGN3 NLGN2

1.06e-04171143GO:0044065
GeneOntologyBiologicalProcessnegative regulation of leukocyte degranulation

LGALS9C LGALS9B LGALS9

1.06e-04171143GO:0043301
GeneOntologyBiologicalProcessnatural killer cell degranulation

LGALS9C LGALS9B LGALS9

1.26e-04181143GO:0043320
GeneOntologyBiologicalProcessmacrophage activation

LGALS9C LGALS9B MYO18A CST7 LGALS9 PLA2G4A

1.28e-041401146GO:0042116
GeneOntologyBiologicalProcessnegative regulation of alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

1.49e-04191143GO:0046642
GeneOntologyBiologicalProcesspositive regulation of defense response to bacterium

LGALS9C LGALS9B LGALS9

1.49e-04191143GO:1900426
GeneOntologyBiologicalProcessregulation of T cell chemotaxis

LGALS9C LGALS9B LGALS9

1.75e-04201143GO:0010819
GeneOntologyBiologicalProcessmale courtship behavior

NLGN4Y NLGN4X

1.80e-0441142GO:0008049
GeneOntologyBiologicalProcesssynaptic vesicle endocytosis

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

1.93e-04961145GO:0048488
GeneOntologyBiologicalProcesssynaptic vesicle clustering

NLGN1 NLGN3 NLGN2

2.35e-04221143GO:0097091
GeneOntologyBiologicalProcesspresynaptic endocytosis

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

2.57e-041021145GO:0140238
GeneOntologyBiologicalProcessregulation of neurotransmitter receptor activity

NLGN1 NLGN3 NETO1 NLGN2

2.60e-04561144GO:0099601
GeneOntologyBiologicalProcessvocalization behavior

NLGN4Y NLGN3 NLGN4X

3.06e-04241143GO:0071625
GeneOntologyBiologicalProcessalpha-beta T cell proliferation

DOCK2 LGALS9C LGALS9B LGALS9

3.19e-04591144GO:0046633
GeneOntologyBiologicalProcessregulation of AMPA receptor activity

NLGN1 NLGN3 NLGN2

3.46e-04251143GO:2000311
GeneOntologyBiologicalProcessregulation of natural killer cell activation

LGALS9C LGALS9B ZBTB1 LGALS9

3.62e-04611144GO:0032814
GeneOntologyBiologicalProcesssynaptic vesicle recycling

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

3.80e-041111145GO:0036465
GeneOntologyBiologicalProcessbehavior

NLGN4Y ANKRD26 LMO3 NLGN1 NR3C1 NPHP4 ADCY8 NLGN3 NLGN4X NETO1 SCN1A NLGN2 GNAO1 PCM1

4.02e-0489111414GO:0007610
GeneOntologyBiologicalProcessheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

LGALS9C LGALS9B NLGN1 LGALS9

4.10e-04631144GO:0007157
GeneOntologyBiologicalProcessregulation of nervous system process

CST7 NLGN1 NLGN3 NLGN4X NETO1 NLGN2

4.28e-041751146GO:0031644
GeneOntologyBiologicalProcessT cell differentiation in thymus

DOCK2 LGALS9C LGALS9B ZBTB1 LGALS9

4.29e-041141145GO:0033077
GeneOntologyBiologicalProcessregulation of respiratory gaseous exchange

NLGN1 NLGN3 NLGN2

4.37e-04271143GO:0043576
GeneOntologyBiologicalProcessinhibitory postsynaptic potential

NLGN1 NLGN3 NLGN2

4.37e-04271143GO:0060080
GeneOntologyBiologicalProcesspositive regulation of glucocorticoid receptor signaling pathway

LMO3 NR3C1

4.48e-0461142GO:2000324
GeneOntologyBiologicalProcessregulation of CD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

4.87e-04281143GO:2000561
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

5.99e-04301143GO:0035739
GeneOntologyBiologicalProcesspositive regulation of dendritic spine development

NLGN1 NR3C1 NLGN3 NLGN2

6.13e-04701144GO:0060999
GeneOntologyBiologicalProcesscourtship behavior

NLGN4Y NLGN4X

6.24e-0471142GO:0007619
GeneOntologyBiologicalProcessregulation of lymphocyte chemotaxis

LGALS9C LGALS9B LGALS9

6.60e-04311143GO:1901623
GeneOntologyBiologicalProcesspositive regulation of regulatory T cell differentiation

LGALS9C LGALS9B LGALS9

6.60e-04311143GO:0045591
GeneOntologyBiologicalProcessnegative regulation of regulated secretory pathway

LGALS9C LGALS9B LGALS9

7.26e-04321143GO:1903306
GeneOntologyBiologicalProcessexcitatory postsynaptic potential

NLGN1 NLGN3 NLGN4X NETO1 NLGN2

7.81e-041301145GO:0060079
GeneOntologyBiologicalProcessT cell chemotaxis

LGALS9C LGALS9B LGALS9

7.95e-04331143GO:0010818
GeneOntologyBiologicalProcesslymphocyte differentiation

DOCK2 LGALS9C LGALS9B DOCK10 POU2F2 ZBTB1 STAT6 LGALS9 SMARCA4 SPINK5

7.96e-0453711410GO:0030098
GeneOntologyBiologicalProcessregulation of signaling receptor activity

NLGN1 LDOC1 NLGN3 NETO1 NLGN2

8.08e-041311145GO:0010469
GeneOntologyBiologicalProcessnegative regulation of dendritic spine morphogenesis

NLGN1 NLGN3

8.30e-0481142GO:0061002
GeneOntologyBiologicalProcessbrainstem development

NLGN4Y NLGN4X

8.30e-0481142GO:0003360
GeneOntologyBiologicalProcessmononuclear cell differentiation

DOCK2 LGALS9C LGALS9B DOCK10 POU2F2 NR3C1 ZBTB1 STAT6 LGALS9 SMARCA4 SPINK5

8.41e-0464011411GO:1903131
GeneOntologyBiologicalProcessregulation of T cell differentiation in thymus

LGALS9C LGALS9B LGALS9

1.11e-03371143GO:0033081
GeneOntologyBiologicalProcessdendritic spine development

DOCK10 NLGN1 NR3C1 NLGN3 NLGN2

1.12e-031411145GO:0060996
GeneOntologyBiologicalProcessregulation of protein localization to synapse

NLGN1 NLGN3 NLGN2

1.20e-03381143GO:1902473
GeneOntologyBiologicalProcesspositive regulation of T cell differentiation

LGALS9C LGALS9B ZBTB1 LGALS9 SMARCA4

1.23e-031441145GO:0045582
GeneOntologyBiologicalProcessT cell differentiation

DOCK2 LGALS9C LGALS9B ZBTB1 STAT6 LGALS9 SMARCA4 SPINK5

1.29e-033821148GO:0030217
GeneOntologyBiologicalProcesspositive regulation of inhibitory postsynaptic potential

NLGN3 NLGN2

1.32e-03101142GO:0097151
GeneOntologyBiologicalProcesschemical synaptic transmission, postsynaptic

NLGN1 NLGN3 NLGN4X NETO1 NLGN2

1.35e-031471145GO:0099565
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated cytotoxicity

LGALS9C LGALS9B LGALS9

1.40e-03401143GO:0045953
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell activation

LGALS9C LGALS9B LGALS9

1.40e-03401143GO:2000515
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated immunity

LGALS9C LGALS9B LGALS9

1.50e-03411143GO:0002716
GeneOntologyBiologicalProcesspositive regulation of T cell migration

LGALS9C LGALS9B LGALS9

1.50e-03411143GO:2000406
GeneOntologyBiologicalProcesslocalization within membrane

DOCK2 LGALS9C LGALS9B ABCA12 VPS39 NLGN1 LGALS9 WDR19 NETO1 ZDHHC6 VPS35L NLGN2

1.54e-0379811412GO:0051668
GeneOntologyBiologicalProcesscellular response to virus

LGALS9C LGALS9B POU2F2 LGALS9

1.57e-03901144GO:0098586
GeneOntologyBiologicalProcesshexose mediated signaling

ADCY8 SMARCA4

1.61e-03111142GO:0009757
GeneOntologyBiologicalProcessglucose mediated signaling pathway

ADCY8 SMARCA4

1.61e-03111142GO:0010255
GeneOntologyBiologicalProcesspostsynaptic density protein 95 clustering

NLGN1 NLGN2

1.61e-03111142GO:0097119
GeneOntologyBiologicalProcesssugar mediated signaling pathway

ADCY8 SMARCA4

1.61e-03111142GO:0010182
GeneOntologyBiologicalProcessnatural killer cell activation involved in immune response

LGALS9C LGALS9B LGALS9

1.61e-03421143GO:0002323
GeneOntologyBiologicalProcessregulation of T cell differentiation

LGALS9C LGALS9B ZBTB1 LGALS9 SMARCA4 SPINK5

1.62e-032261146GO:0045580
GeneOntologyBiologicalProcessmembrane organization

DOCK2 ABCA12 VPS39 NLGN4Y MYO18A NLGN1 PLEKHA8P1 NLGN3 NLGN4X SEC24C PLA2G4A NLGN2 KLHL12

1.62e-0391411413GO:0061024
GeneOntologyBiologicalProcessregulation of dendritic spine development

NLGN1 NR3C1 NLGN3 NLGN2

1.63e-03911144GO:0060998
GeneOntologyBiologicalProcesspositive regulation of SMAD protein signal transduction

LGALS9C LGALS9B LGALS9

1.73e-03431143GO:0060391
GeneOntologyBiologicalProcesspositive regulation of synaptic transmission, glutamatergic

NLGN1 NLGN3 NLGN2

1.73e-03431143GO:0051968
GeneOntologyCellularComponentsymmetric, GABA-ergic, inhibitory synapse

NLGN4Y NLGN3 NLGN4X NLGN2

8.39e-1041144GO:0098983
GeneOntologyCellularComponentexcitatory synapse

NLGN4Y NLGN1 ADCY8 NLGN3 NLGN4X NETO1 NLGN2 GNAO1

1.27e-071071148GO:0060076
GeneOntologyCellularComponentsymmetric synapse

NLGN4Y NLGN3 NLGN4X NLGN2

5.78e-07131144GO:0032280
GeneOntologyCellularComponentinhibitory synapse

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

6.70e-07311145GO:0060077
GeneOntologyCellularComponentasymmetric, glutamatergic, excitatory synapse

NLGN4Y NLGN1 NLGN3 NLGN4X

8.19e-06241144GO:0098985
GeneOntologyCellularComponentmicrotubule organizing center

HMBOX1 KIF23 OFD1 MYO18A ANKRD26 EVC NR3C1 NPHP4 KIAA1217 TTC39A KLHL12 AGBL2 PCM1 DEUP1 SMTNL2

1.41e-0491911415GO:0005815
GeneOntologyCellularComponentglycinergic synapse

NLGN4Y NLGN4X NLGN2

1.68e-04201143GO:0098690
GeneOntologyCellularComponentepidermal lamellar body

ABCA12 SPINK5

1.76e-0441142GO:0097209
GeneOntologyCellularComponentGABA-ergic synapse

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2 GNAO1

2.82e-041641146GO:0098982
GeneOntologyCellularComponentpostsynaptic specialization membrane

NLGN4Y NLGN1 NLGN3 NLGN4X NETO1 NLGN2

8.27e-042011146GO:0099634
GeneOntologyCellularComponentchromatin

HMBOX1 BRPF3 ENC1 ZBTB8B KDM3B POU2F1 POU2F2 SIN3A NR6A1 NR3C1 TFCP2 HNRNPL STAT6 HOXC6 NACC2 SMARCA4 RORB BICRAL

1.07e-03148011418GO:0000785
GeneOntologyCellularComponentCul3-RING ubiquitin ligase complex

ENC1 KLHL3 KLHL12

1.25e-03391143GO:0031463
GeneOntologyCellularComponentinner dynein arm

DNAH7 DNAH1

1.29e-03101142GO:0036156
GeneOntologyCellularComponentpostsynaptic specialization

NLGN4Y MPDZ NLGN1 NR3C1 ADCY8 NLGN3 NLGN4X NETO1 NLGN2

1.75e-035031149GO:0099572
GeneOntologyCellularComponentneuron to neuron synapse

NLGN4Y MPDZ NLGN1 NR3C1 ADCY8 NLGN3 NLGN4X NETO1 NLGN2

2.28e-035231149GO:0098984
GeneOntologyCellularComponentdendrite

NLGN4Y DOCK10 MPDZ NLGN1 NR3C1 SCGN ADCY8 NLGN3 NLGN4X SACS NLGN2 GNAO1

2.52e-0385811412GO:0030425
GeneOntologyCellularComponentcentriole

OFD1 NPHP4 AGBL2 PCM1 DEUP1

2.54e-031721145GO:0005814
GeneOntologyCellularComponentdendritic tree

NLGN4Y DOCK10 MPDZ NLGN1 NR3C1 SCGN ADCY8 NLGN3 NLGN4X SACS NLGN2 GNAO1

2.57e-0386011412GO:0097447
GeneOntologyCellularComponentGBAF complex

SMARCA4 BICRAL

2.57e-03141142GO:0140288
GeneOntologyCellularComponentmembrane coat

COPB1 VPS39 SEC24C KLHL12

2.72e-031061144GO:0030117
GeneOntologyCellularComponentcoated membrane

COPB1 VPS39 SEC24C KLHL12

2.72e-031061144GO:0048475
GeneOntologyCellularComponentsomatodendritic compartment

NLGN4Y ENC1 DOCK10 MPDZ NLGN1 NR3C1 SCGN PDE10A ADCY8 NLGN3 NLGN4X SACS SCN1A NLGN2 GNAO1

2.76e-03122811415GO:0036477
GeneOntologyCellularComponentCOPII vesicle coat

SEC24C KLHL12

3.37e-03161142GO:0030127
MousePhenoabnormal social investigation

SLC9A9 NLGN1 PDE10A NLGN3 SCN1A NLGN2 GNAO1 PCM1

1.79e-05171938MP:0001360
DomainNlgn

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

7.42e-1251135IPR000460
DomainCarboxylesterase_B_CS

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

9.18e-09131135IPR019819
DomainCARBOXYLESTERASE_B_2

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

1.42e-08141135PS00941
DomainCOesterase

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

1.42e-08141135PF00135
DomainCarbesteraseB

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

1.42e-08141135IPR002018
DomainNLGN4

NLGN4Y NLGN4X

3.63e-0521132IPR030025
Domain-

NLGN4Y YTHDC2 NLGN1 NLGN3 NLGN4X NLGN2

8.55e-0511911363.40.50.1820
DomainAB_hydrolase

NLGN4Y YTHDC2 NLGN1 NLGN3 NLGN4X NLGN2

8.55e-051191136IPR029058
DomainGalectin_CRD

LGALS9C LGALS9B LGALS9

9.31e-05151133IPR001079
DomainGal-bind_lectin

LGALS9C LGALS9B LGALS9

9.31e-05151133PF00337
DomainGal-bind_lectin

LGALS9C LGALS9B LGALS9

9.31e-05151133SM00908
DomainGALECTIN

LGALS9C LGALS9B LGALS9

9.31e-05151133PS51304
DomainGLECT

LGALS9C LGALS9B LGALS9

9.31e-05151133SM00276
DomainTF_octamer

POU2F1 POU2F2

1.08e-0431132IPR000972
DomainBTB

ENC1 ZBTB8B ZBTB1 KLHL3 NACC2 KLHL12

1.45e-041311136PF00651
DomainBTB

ENC1 ZBTB8B ZBTB1 KLHL3 NACC2 KLHL12

4.27e-041601136PS50097
Domain-

HMBOX1 POU2F1 POU2F2

5.67e-042711331.10.260.40
DomainLambda_DNA-bd_dom

HMBOX1 POU2F1 POU2F2

7.03e-04291133IPR010982
DomainBTB

ENC1 ZBTB8B ZBTB1 KLHL3 NACC2 KLHL12

7.94e-041801136SM00225
DomainBTB/POZ_dom

ENC1 ZBTB8B ZBTB1 KLHL3 NACC2 KLHL12

9.16e-041851136IPR000210
DomainClathrin_H-chain/VPS_repeat

VPS39 WDR19

9.92e-0481132IPR000547
DomainSKP1/BTB/POZ

ENC1 ZBTB8B ZBTB1 KLHL3 NACC2 KLHL12

1.02e-031891136IPR011333
DomainEF-hand-dom_pair

SCGN RYR2 STAT6 CAPN13 CAPN8 TBC1D8 SCN1A

1.82e-032871137IPR011992
DomainDHR-1_domain

DOCK2 DOCK10

1.93e-03111132IPR027007
DomainDHR_2

DOCK2 DOCK10

1.93e-03111132PS51651
DomainDHR_1

DOCK2 DOCK10

1.93e-03111132PS51650
DomainDHR-2

DOCK2 DOCK10

1.93e-03111132PF06920
DomainDOCK

DOCK2 DOCK10

1.93e-03111132IPR026791
DomainDOCK_C

DOCK2 DOCK10

1.93e-03111132IPR010703
DomainDOCK-C2

DOCK2 DOCK10

1.93e-03111132PF14429
DomainDHR-2

DOCK2 DOCK10

1.93e-03111132IPR027357
DomainBTB-kelch_protein

ENC1 KLHL3 KLHL12

2.23e-03431133IPR017096
DomainZnf_hrmn_rcpt

NR6A1 NR3C1 RORB

2.71e-03461133IPR001628
DomainNUCLEAR_REC_DBD_2

NR6A1 NR3C1 RORB

2.71e-03461133PS51030
DomainNUCLEAR_REC_DBD_1

NR6A1 NR3C1 RORB

2.71e-03461133PS00031
DomainZnF_C4

NR6A1 NR3C1 RORB

2.71e-03461133SM00399
Domainzf-C4

NR6A1 NR3C1 RORB

2.71e-03461133PF00105
DomainNuclear_hrmn_rcpt

NR6A1 NR3C1 RORB

2.71e-03461133IPR001723
DomainCalpain_III

CAPN13 CAPN8

2.71e-03131132PF01067
DomainCalpain_domain_III

CAPN13 CAPN8

2.71e-03131132IPR022682
DomainNucl_hrmn_rcpt_lig-bd

NR6A1 NR3C1 RORB

3.06e-03481133IPR000536
DomainHOLI

NR6A1 NR3C1 RORB

3.06e-03481133SM00430
DomainHormone_recep

NR6A1 NR3C1 RORB

3.06e-03481133PF00104
DomainDynein_heavy_chain_D4_dom

DNAH7 DNAH1

3.15e-03141132IPR024317
DomainDynein_HC_stalk

DNAH7 DNAH1

3.15e-03141132IPR024743
DomainDynein_heavy_dom-2

DNAH7 DNAH1

3.15e-03141132IPR013602
DomainDHC_N2

DNAH7 DNAH1

3.15e-03141132PF08393
DomainCalpain_cysteine_protease

CAPN13 CAPN8

3.15e-03141132IPR022684
DomainMT

DNAH7 DNAH1

3.15e-03141132PF12777
DomainAAA_8

DNAH7 DNAH1

3.15e-03141132PF12780
DomainDHC_fam

DNAH7 DNAH1

3.62e-03151132IPR026983
DomainPeptidase_C2

CAPN13 CAPN8

3.62e-03151132PF00648
DomainDynein_heavy

DNAH7 DNAH1

3.62e-03151132PF03028
DomainCysPc

CAPN13 CAPN8

3.62e-03151132SM00230
DomainPeptidase_C2_calpain_cat

CAPN13 CAPN8

3.62e-03151132IPR001300
DomainDynein_heavy_dom

DNAH7 DNAH1

3.62e-03151132IPR004273
DomainCALPAIN_CAT

CAPN13 CAPN8

3.62e-03151132PS50203
DomainPOU

POU2F1 POU2F2

4.12e-03161132SM00352
DomainPOU_dom

POU2F1 POU2F2

4.12e-03161132IPR000327
DomainPou

POU2F1 POU2F2

4.12e-03161132PF00157
DomainPOU_1

POU2F1 POU2F2

4.12e-03161132PS00035
DomainPOU_2

POU2F1 POU2F2

4.12e-03161132PS00465
DomainPOU_3

POU2F1 POU2F2

4.12e-03161132PS51179
DomainPOU

POU2F1 POU2F2

4.65e-03171132IPR013847
DomainIon_trans_dom

TRPM6 KCNH8 RYR2 SCN1A

5.09e-031141134IPR005821
DomainIon_trans

TRPM6 KCNH8 RYR2 SCN1A

5.09e-031141134PF00520
Domain-

SCGN RYR2 STAT6 CAPN13 CAPN8 TBC1D8

5.12e-0326111361.10.238.10
DomainZnf_NHR/GATA

NR6A1 NR3C1 RORB

5.23e-03581133IPR013088
DomainKelch

ENC1 KLHL3 KLHL12

5.23e-03581133SM00612
DomainP-loop_NTPase

KIF23 ABCA12 MYO18A YTHDC2 PAPSS2 DNAH7 ABCC6 DNAH1 NLRP9 SMARCA4 HFM1 GNAO1

5.24e-0384811312IPR027417
DomainGal_Oxase/kelch_b-propeller

ENC1 KLHL3 KLHL12

5.48e-03591133IPR011043
Domain-

ABCA12 MYO18A YTHDC2 PAPSS2 DNAH7 ABCC6 DNAH1 NLRP9 SMARCA4 HFM1 GNAO1

5.53e-03746113113.40.50.300
DomainBACK

ENC1 KLHL3 KLHL12

5.74e-03601133SM00875
DomainBACK

ENC1 KLHL3 KLHL12

6.02e-03611133IPR011705
DomainBACK

ENC1 KLHL3 KLHL12

6.02e-03611133PF07707
DomainARM-like

MON2 DOCK2 SMG1 COPB1 DOCK10 XPO1

6.02e-032701136IPR011989
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

9.26e-0732805MM15326
PathwayWP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV

NLGN1 RYR2 NLGN3 NLGN4X NLGN2

1.09e-0633805M39875
PathwayWP_NRXN1_DELETION_SYNDROME

NLGN1 NLGN3 NLGN4X NLGN2

2.77e-0618804M48098
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

1.58e-0556805M27616
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

3.80e-0567805MM15327
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

1.33e-0487805M27617
Pubmed

Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

3.62e-135115537865312
Pubmed

Synapse formation: if it looks like a duck and quacks like a duck ...

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

3.62e-135115510996085
Pubmed

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

2.17e-126115521838267
Pubmed

Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

2.17e-126115529724786
Pubmed

Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

2.01e-118115530871858
Pubmed

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.

NLGN4Y NLGN3 NLGN4X NLGN2

1.13e-104115412669065
Pubmed

Homodimerization and isoform-specific heterodimerization of neuroligins.

NLGN4Y NLGN3 NLGN4X NLGN2

1.13e-104115422671294
Pubmed

Analysis of four neuroligin genes as candidates for autism.

NLGN4Y NLGN1 NLGN3 NLGN4X

1.13e-104115416077734
Pubmed

SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

1.65e-1011115532973045
Pubmed

Behavioral phenotypes of genetic mouse models of autism.

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

1.65e-1011115526403076
Pubmed

Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins.

NLGN1 NLGN3 NLGN4X NLGN2

5.66e-105115415620359
Pubmed

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

1.06e-0915115518227507
Pubmed

Binding of neuroligins to PSD-95.

NLGN1 NLGN3 NLGN4X NLGN2

1.41e-08911549278515
Pubmed

DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors.

NLGN4Y NLGN1 NLGN3 NLGN4X NLGN2

2.25e-0826115534848499
Pubmed

Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation.

LGALS9C LGALS9B LGALS9

3.52e-083115319776007
Pubmed

Galectin-9 regulates follicular helper T cells to inhibit humoral autoimmunity-induced pulmonary fibrosis.

LGALS9C LGALS9B LGALS9

3.52e-083115333316546
Pubmed

Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin.

LGALS9C LGALS9B LGALS9

3.52e-08311539038233
Pubmed

Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties.

NLGN1 NLGN3 NLGN2

3.52e-083115328607166
Pubmed

Protective effect of Galectin-9 in murine model of lung emphysema: Involvement of neutrophil migration and MMP-9 production.

LGALS9C LGALS9B LGALS9

3.52e-083115328704475
Pubmed

Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.

LGALS9C LGALS9B LGALS9

3.52e-083115323836896
Pubmed

Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes.

LGALS9C LGALS9B LGALS9

3.52e-08311537890611
Pubmed

Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner.

LGALS9C LGALS9B LGALS9

3.52e-083115322341088
Pubmed

Galectin-9 Is a Novel Regulator of Epithelial Restitution.

LGALS9C LGALS9B LGALS9

3.52e-083115332380082
Pubmed

Galectin-9-mediated protection from allo-specific T cells as a mechanism of immune privilege of corneal allografts.

LGALS9C LGALS9B LGALS9

3.52e-083115323667648
Pubmed

Developmental effects of ectopic expression of the glucocorticoid receptor DNA binding domain are alleviated by an amino acid substitution that interferes with homeodomain binding.

POU2F1 POU2F2 NR3C1

3.52e-083115310490647
Pubmed

Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9.

LGALS9C LGALS9B LGALS9

3.52e-083115328877989
Pubmed

Galectin-9 ameliorates immune complex-induced arthritis by regulating Fc gamma R expression on macrophages.

LGALS9C LGALS9B LGALS9

3.52e-083115319800850
Pubmed

The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy.

LGALS9C LGALS9B LGALS9

3.52e-083115338987795
Pubmed

Recruitment of octamer transcription factors to DNA by glucocorticoid receptor.

POU2F1 POU2F2 NR3C1

3.52e-08311539584182
Pubmed

Oncogenic miR-93-5p/Gal-9 axis drives CD8 (+) T-cell inactivation and is a therapeutic target for hepatocellular carcinoma immunotherapy.

LGALS9C LGALS9B LGALS9

3.52e-083115337105392
Pubmed

Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits.

NLGN1 NLGN3 NLGN2

3.52e-083115329100073
Pubmed

Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.

LGALS9C LGALS9B LGALS9

3.52e-083115336479526
Pubmed

Profiling Lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological human pregnancy.

LGALS9C LGALS9B LGALS9

3.52e-083115323242525
Pubmed

Galectin-9 in allergic airway inflammation and hyper-responsiveness in mice.

LGALS9C LGALS9B LGALS9

3.52e-083115319851072
Pubmed

The Role of Galectin-9 as Mediator of Atopic Dermatitis: Effect on Keratinocytes.

LGALS9C LGALS9B LGALS9

3.52e-083115333923930
Pubmed

Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases.

LGALS9C LGALS9B LGALS9

3.52e-083115331969388
Pubmed

Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.

LGALS9C LGALS9B LGALS9

3.52e-083115335241678
Pubmed

Possible regulatory role of galectin-9 on Ascaris suum-induced eosinophilic lung inflammation in mice.

LGALS9C LGALS9B LGALS9

3.52e-083115322627368
Pubmed

Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses.

NLGN1 NLGN3 NLGN2

3.52e-083115326291161
Pubmed

Galectin-9 is required for endometrial regenerative cells to induce long-term cardiac allograft survival in mice.

LGALS9C LGALS9B LGALS9

3.52e-083115333153471
Pubmed

T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses.

LGALS9C LGALS9B LGALS9

3.52e-083115322052881
Pubmed

Neuroligin-3 is a neuronal adhesion protein at GABAergic and glutamatergic synapses.

NLGN1 NLGN3 NLGN2

3.52e-083115317897391
Pubmed

Neuroligins determine synapse maturation and function.

NLGN1 NLGN3 NLGN2

3.52e-083115316982420
Pubmed

Galectin-9 supports primary T cell transendothelial migration in a glycan and integrin dependent manner.

LGALS9C LGALS9B LGALS9

3.52e-083115335643073
Pubmed

Galectin-9 functionally impairs natural killer cells in humans and mice.

LGALS9C LGALS9B LGALS9

3.52e-083115323408620
Pubmed

Galectin-9 Is Critical for Mucosal Adaptive Immunity through the T Helper 17-IgA Axis.

LGALS9C LGALS9B LGALS9

3.52e-083115329458010
Pubmed

Cooperative Interactions of Oligosaccharide and Peptide Moieties of a Glycopeptide Derived from IgE with Galectin-9.

LGALS9C LGALS9B LGALS9

3.52e-083115326582205
Pubmed

Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.

LGALS9C LGALS9B LGALS9

3.52e-08311539153289
Pubmed

Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice.

LGALS9C LGALS9B LGALS9

3.52e-083115318974023
Pubmed

Cell surface galectin-9 expressing Th cells regulate Th17 and Foxp3+ Treg development by galectin-9 secretion.

LGALS9C LGALS9B LGALS9

3.52e-083115323144904
Pubmed

Impaired Gal-9 Dysregulates the PBMC-Induced Th1/Th2 Imbalance in Abortion-Prone Matings.

LGALS9C LGALS9B LGALS9

3.52e-083115329651447
Pubmed

The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity.

LGALS9C LGALS9B LGALS9

3.52e-083115321146220
Pubmed

Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents.

NLGN4Y NLGN3 NLGN4X

3.52e-083115332011705
Pubmed

Regulation of M1‑type and M2‑type macrophage polarization in RAW264.7 cells by Galectin‑9.

LGALS9C LGALS9B LGALS9

3.52e-083115328990062
Pubmed

Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices.

LGALS9C LGALS9B LGALS9

3.52e-083115318579572
Pubmed

Conditional ablation of neuroligin-1 in CA1 pyramidal neurons blocks LTP by a cell-autonomous NMDA receptor-independent mechanism.

NLGN1 NLGN3 NLGN2

3.52e-083115327217145
Pubmed

Crystal structure of the galectin-9 N-terminal carbohydrate recognition domain from Mus musculus reveals the basic mechanism of carbohydrate recognition.

LGALS9C LGALS9B LGALS9

3.52e-083115316990264
Pubmed

Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue.

LGALS9C LGALS9B LGALS9

3.52e-083115318005988
Pubmed

Galectin-9 ameliorates clinical severity of MRL/lpr lupus-prone mice by inducing plasma cell apoptosis independently of Tim-3.

LGALS9C LGALS9B LGALS9

3.52e-083115323585851
Pubmed

Analysis of the neuroligin 4Y gene in patients with autism.

NLGN4Y NLGN3 NLGN4X

3.52e-083115318628683
Pubmed

Galectin-9 ameliorates anti-GBM glomerulonephritis by inhibiting Th1 and Th17 immune responses in mice.

LGALS9C LGALS9B LGALS9

3.52e-083115324477688
Pubmed

A unique role for galectin-9 in angiogenesis and inflammatory arthritis.

LGALS9C LGALS9B LGALS9

3.52e-083115329433546
Pubmed

Alarmin function of galectin-9 in murine respiratory tularemia.

LGALS9C LGALS9B LGALS9

3.52e-083115325898318
Pubmed

Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells.

LGALS9C LGALS9B LGALS9

3.52e-083115331937306
Pubmed

Intestinal epithelial cells express galectin-9 in patients with food allergy that plays a critical role in sustaining allergic status in mouse intestine.

LGALS9C LGALS9B LGALS9

3.52e-083115321426359
Pubmed

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis.

LGALS9C LGALS9B LGALS9

3.52e-083115318282810
Pubmed

Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.

LGALS9C LGALS9B LGALS9

3.52e-083115324083426
Pubmed

Galectin-9 in synergy with NF-κB inhibition restores immune regulatory capability in dendritic cells of subjects with food allergy.

LGALS9C LGALS9B LGALS9

3.52e-083115337279535
Pubmed

The protective function of galectin-9 in liver ischemia and reperfusion injury in mice.

LGALS9C LGALS9B LGALS9

3.52e-083115325931247
Pubmed

Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina.

NLGN4Y NLGN4X NLGN2

3.52e-083115321282647
Pubmed

Galectin-9 protects mice from the Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes.

LGALS9C LGALS9B LGALS9

3.52e-083115317560833
Pubmed

Advancing the understanding of autism disease mechanisms through genetics.

NLGN4Y NLGN3 NLGN4X SCN1A

7.93e-0813115427050589
Pubmed

SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.

LGALS9C LGALS9B LGALS9

1.41e-074115338686388
Pubmed

Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells.

LGALS9C LGALS9B LGALS9

1.41e-074115322677125
Pubmed

Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.

LGALS9C LGALS9B LGALS9

1.41e-074115319234217
Pubmed

Tim-3/Galectin-9 signaling pathway is involved in the cytokine changes in mice with alveolar echinococcosis.

LGALS9C LGALS9B LGALS9

1.41e-074115335715604
Pubmed

Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions.

LGALS9C LGALS9B LGALS9

1.41e-074115319017954
Pubmed

Galectin-9: A novel promoter of atherosclerosis progression.

LGALS9C LGALS9B LGALS9

1.41e-074115336459823
Pubmed

Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models.

LGALS9C LGALS9B LGALS9

1.41e-074115329611821
Pubmed

Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2.

LGALS9C LGALS9B LGALS9

1.41e-074115333727589
Pubmed

The Galectin-9/Tim-3 pathway is involved in the regulation of NK cell function at the maternal-fetal interface in early pregnancy.

LGALS9C LGALS9B LGALS9

1.41e-074115325578313
Pubmed

[Expression and significance of galectin-3 and galectin-9 in mice nasal mucosa with allergic rhinitis].

LGALS9C LGALS9B LGALS9

1.41e-074115318826117
Pubmed

The expression of Galectin-9 correlates with mTOR and AMPK in murine colony-forming erythroid progenitors.

LGALS9C LGALS9B LGALS9

1.41e-074115338853593
Pubmed

[Expression of Galectin-9 and Tim-3 in lungs of mice with asthma].

LGALS9C LGALS9B LGALS9

1.41e-074115321575348
Pubmed

Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts.

LGALS9C LGALS9B LGALS9

1.41e-074115318346632
Pubmed

Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice.

LGALS9C LGALS9B LGALS9

1.41e-074115319670381
Pubmed

Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury.

LGALS9C LGALS9B LGALS9

1.41e-074115325450716
Pubmed

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity.

LGALS9C LGALS9B LGALS9

1.41e-074115316286920
Pubmed

Galectin-9 regulates the threshold of B cell activation and autoimmunity.

LGALS9C LGALS9B LGALS9

1.41e-074115334369876
Pubmed

Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage.

NLGN1 NLGN3 NLGN2

1.41e-074115330056576
Pubmed

Targeting the CD146/Galectin-9 axis protects the integrity of the blood-brain barrier in experimental cerebral malaria.

LGALS9C LGALS9B LGALS9

1.41e-074115333203936
Pubmed

Ultrasonic vocalizations in mouse models for speech and socio-cognitive disorders: insights into the evolution of vocal communication.

NLGN4Y NLGN3 NLGN4X

1.41e-074115320579107
Pubmed

Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.

LGALS9C LGALS9B LGALS9

1.41e-074115333963043
Pubmed

Newly characterized decidual Tim-3+ Treg cells are abundant during early pregnancy and driven by IL-27 coordinately with Gal-9 from trophoblasts.

LGALS9C LGALS9B LGALS9

1.41e-074115333107565
Pubmed

Lipopolysaccharide mediates time-dependent macrophage M1/M2 polarization through the Tim-3/Galectin-9 signalling pathway.

LGALS9C LGALS9B LGALS9

1.41e-074115330763585
Pubmed

Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells.

LGALS9C LGALS9B LGALS9

1.41e-074115319362679
Pubmed

Intestinal Lamina Propria CD4+ T Cells Promote Bactericidal Activity of Macrophages via Galectin-9 and Tim-3 Interaction during Salmonella enterica Serovar Typhimurium Infection.

LGALS9C LGALS9B LGALS9

1.41e-074115329844236
Pubmed

Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response.

LGALS9C LGALS9B LGALS9

1.41e-074115320463811
Pubmed

Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas.

LGALS9C LGALS9B LGALS9

1.41e-074115332855403
Pubmed

Galectin-3 mediates oligomerization of secreted hensin using its carbohydrate-recognition domain.

LGALS9C LGALS9B LGALS9

1.41e-074115323657851
InteractionNLGN4Y interactions

NLGN4Y HNRNPL NLGN3

3.48e-0661143int:NLGN4Y
GeneFamilyBasic leucine zipper proteins|BTB domain containing

ENC1 ZBTB8B ZBTB1 KLHL3 NACC2 KLHL12

1.43e-05134716861
GeneFamilyGalectins

LGALS9C LGALS9B LGALS9

2.55e-0515713629
GeneFamilyKelch like|BTB domain containing

ENC1 KLHL3 KLHL12

5.97e-0442713617
GeneFamilyNuclear hormone receptors

NR6A1 NR3C1 RORB

9.39e-044971371
GeneFamilyC2 domain containing|Calpains

CAPN13 CAPN8

1.54e-0315712975
GeneFamilyDyneins, axonemal

DNAH7 DNAH1

1.99e-0317712536
GeneFamilyPOU class homeoboxes and pseudogenes

POU2F1 POU2F2

3.65e-0323712523
GeneFamilyPHD finger proteins

SP100 BRPF3 KMT2B

5.34e-039071388
CoexpressionGSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_UP

HMBOX1 VPS39 POU2F1 SIN3A LDOC1 KLHL12 SPINK5

2.27e-061351157M447
CoexpressionGSE17721_LPS_VS_POLYIC_16H_BMDC_DN

TRPM6 HMBOX1 ENC1 PSMB6 NR3C1 TBC1D8 TBC1D13 NLGN2

2.94e-062001158M3819
CoexpressionGSE2405_0H_VS_9H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP

POU2F2 YTHDC2 ZBED5 SACS SCN1A SMARCA4 SMTNL2

2.78e-051981157M6217
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH8 ENC1 NLGN4X SCN1A PLA2G4A RORB PCDH1

2.68e-07167115749b19159c62d33d65ed1e59a148c11ae902fd41c
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LMO3 NR6A1 CAPN13 CAPN8 TBC1D8 KIAA1217 FHIP1A

3.82e-0717611573bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LMO3 NR6A1 ABCC6 CAPN8 KIAA1217 FHIP1A SLC44A3

5.54e-0718611572ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

TRPM6 KCNH8 LMO3 CAPN13 KIAA1217 FHIP1A SPINK5

5.75e-0718711578407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellCOVID-19-lung|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 SP100 DOCK10 LMO3 PAPSS2 STAT6 CAPN8

8.72e-071991157155b03b859157013e9142e9248551369127d9204
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH8 LMO3 NLGN4X SCN1A RORB PCDH1

7.88e-061821156bfb725fff3d20066d8ac0a6ba2f88498fcbd876e
ToppCellPCW_05-06-Neuronal-Neuronal_SCP|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KCNH8 DOCK10 NLGN1 NLGN4X SCN1A PCDH1

7.88e-061821156b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 TOP6BL PAPSS2 CAPN8 NLGN4X FHIP1A

7.88e-061821156a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH8 CBR3 NLGN4X SCN1A RORB PCDH1

8.13e-061831156e0854864d377e158a4793088d1cb6b3dbf2c805d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 SP100 KCNH8 DOCK10 POU2F2 NETO1

9.19e-0618711568fa454dc4e6a3e8e2bb2ad803acc579e0d3f76da
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 SP100 KCNH8 DOCK10 POU2F2 NETO1

9.19e-061871156edad646d5eb1d70b768dc21fe02ef5265214e8e6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 NLGN4Y TOP6BL PAPSS2 CAPN8 FHIP1A

9.19e-06187115677886f99c229610abd28c4c370d2c7d1536c9782
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

SLC9A9 SP100 NLGN4Y DOCK10 NLGN1 ARHGAP28

1.01e-05190115662a3ec1ae0829602b0569cc051210551644f1d46
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

LMO3 NLGN1 ABCC6 CAPN8 SCN1A FHIP1A

1.04e-051911156276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellAdult-Immune-monocyte-D231|Adult / Lineage, Cell type, age group and donor

DOCK2 SLC9A9 DOCK10 POU2F2 TBC1D8 GNAO1

1.17e-051951156ea24da6fea1487acb1e56c28c0649858cc0a12bd
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LMO3 NR6A1 CAPN8 SCN1A KIAA1217 FHIP1A

1.31e-0519911565f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass

TOP6BL ZBTB1 NACC2 ZNF70 PLA2G4A AGBL2

1.31e-051991156fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCellBronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SLC9A9 DOCK10 NR6A1 TFCP2 TBC1D8 TBC1D13

1.35e-052001156a4c41509ca936e137230a6ae548c90f18a566d12
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 ADCY8 RYR2 CCDC7 CAPN8

5.98e-051601155c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 ADCY8 RYR2 CCDC7 CAPN8

5.98e-05160115525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LMO3 NR6A1 CAPN8 TBC1D8 KIAA1217

6.34e-0516211555c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCelldroplet-Lung-nan-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH1 TBC1D8 PHKG1 TTC39A AGBL2

7.33e-051671155f33cef917fa733adf6d5a9a9e989a4d9fd462a8f
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 NLGN1 RYR2 DNAH1 SPINK5

7.75e-05169115512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellCOVID-19-kidney-Bcells|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 KCNH8 DOCK10 POU2F2 NETO1

8.19e-0517111558e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNH8 IRAK1BP1 NR6A1 BICRAL PCDH1

8.65e-05173115523e50492bc673aff9df95d97f0b9be4ce57cbf01
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

LGALS9B LMO3 CAPN13 CAPN8 KIAA1217

8.65e-051731155464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KMT2B ENC1 POU2F2 SACS NETO1

8.89e-051741155ebe6ce173ad12d4a2afa39f8d6185c0e4f97fb1e
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IRAK1BP1 PAPSS2 WDR19 NLGN3 SACS

9.13e-051751155a5db428b078938627e61b7e944c1e0c1d61ac2da
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IRAK1BP1 PAPSS2 WDR19 NLGN3 SACS

9.13e-0517511558b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POU2F2 SCGN ADCY8 RYR2 NETO1

9.13e-051751155887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellControl-B_cells-B_cells|Control / group, cell type (main and fine annotations)

DOCK2 SP100 KCNH8 POU2F2 NETO1

9.38e-051761155d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCellfacs-Skin-Anagen-3m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 SP100 DOCK10 CST7 SACS

9.63e-0517711557853430fb0d1a18d835e8956777e0616c5d7d412
ToppCellwk_15-18-Epithelial-PNS-Schwann_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ENC1 NLGN4X SACS SCN1A RORB

9.63e-0517711555357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCellfacs-Skin-Anagen-3m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 SP100 DOCK10 CST7 SACS

9.63e-051771155395f005f019aabb18738d3a10a04c37f216deda3
ToppCellfacs-Skin-Anagen-3m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 SP100 DOCK10 CST7 SACS

9.63e-0517711559a5bf67a801826d094f679dd2189b62296c9694f
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

HMBOX1 MYO18A ANKRD26 POU2F1 GNAO1

9.63e-051771155e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

LMO3 NR6A1 CAPN8 KIAA1217 FHIP1A

9.89e-051781155f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HMBOX1 POU2F1 POU2F2 ZNF70 GNAO1

1.02e-041791155163f5430d72ea0c1b239ea5d21e53be536636d3d
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HMBOX1 POU2F1 POU2F2 ZNF70 GNAO1

1.02e-0417911550624dd537a68736f4d7b8b4de2c56168ed0e60a9
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNH8 KDM3B LMO3 NLGN4X PCDH1

1.04e-041801155c72f15763ba707189e29c85db533557f01c7fdb1
ToppCellCOVID-19-kidney-Bcells|kidney / Disease (COVID-19 only), tissue and cell type

DOCK2 KCNH8 DOCK10 POU2F2 NETO1

1.04e-0418011555650fc7ebcdf5e0be9a217a58d36a8386d59fd1b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 KCNH8 DOCK10 POU2F2 NETO1

1.04e-04180115565c069585737302a69b9a01476f4eb8b50cb2bfd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPSS2 LGALS9 CAPN8 NLGN4X PLA2G4A

1.07e-04181115522363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH8 DOCK10 NLGN4X SCN1A RORB

1.07e-041811155fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

LMO3 PDE10A CAPN13 CAPN8 KIAA1217

1.10e-0418211553f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LMO3 NLGN1 PLA2G4A TTC39A FHIP1A

1.10e-04182115517ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LMO3 NLGN1 PLA2G4A TTC39A FHIP1A

1.13e-041831155e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 OBSCN RYR2 DNAH1 CAPN8

1.16e-0418411552cbed6462fea2622871bb7e49b0df3d984239281
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

LMO3 NLGN1 CAPN8 SCN1A FHIP1A

1.16e-041841155369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellControl-Epithelial_alveolar-AT_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LMO3 NLGN1 TTC39A FHIP1A SLC44A3

1.16e-04184115551e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNH8 DOCK10 NLGN4X FAM186A SCN1A

1.16e-0418411557aa245b73e10fd73d292e822de6b72920aa12355
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 OBSCN RYR2 DNAH1 CAPN8

1.16e-041841155ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 SLC9A9 DOCK10 CST7 GNAO1

1.16e-0418411554f4aeef3b821a003e857fe4a195124d44b2d7479
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 OBSCN RYR2 DNAH1 CAPN8

1.16e-0418411552b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

LMO3 NR6A1 CAPN13 CAPN8 FHIP1A

1.16e-041841155102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LMO3 NLGN1 PLA2G4A TTC39A FHIP1A

1.16e-041841155ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

LMO3 NR6A1 CAPN8 KIAA1217 FHIP1A

1.19e-04185115598b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

LMO3 CAPN13 CAPN8 KIAA1217 FHIP1A

1.19e-041851155cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellwk_08-11-Epithelial-PNS-COL20A1+_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

KCNH8 LMO3 NLGN4X PLA2G4A RORB

1.19e-041851155abec2a49fe0f0fa4cba49347207a1ee317333657
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH8 DOCK10 NLGN4X SCN1A RORB

1.19e-04185115556c7a0dbf141728ac76b8c90af197719942ca67c
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KCNH8 DOCK10 NLGN1 NLGN4X SCN1A

1.19e-041851155a8946379fc066903fe8f4bc9cbf693b7b424a0cd
ToppCellCOVID-19-lung-B_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 KCNH8 DOCK10 POU2F2 NETO1

1.19e-041851155e8f1ad580f19705b5ca1d7d8867b2125f4891684
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NLGN1 NLGN3 HOXC6 NACC2 SCN1A

1.22e-041861155bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NLGN4Y EVC NLGN4X RORB SMTNL2

1.22e-041861155f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

LMO3 NR6A1 CAPN8 KIAA1217 FHIP1A

1.25e-04187115581cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell(04)_Pre-ciliated-(3)_72hpi|(04)_Pre-ciliated / shred by cell type and Timepoint

PSMB6 EDC4 NPHP4 AGBL2 DEUP1

1.28e-041881155f911dc61b008b60aaa2a1e9354085f480a669e2c
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

LMO3 NR6A1 CAPN8 KIAA1217 FHIP1A

1.28e-041881155c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KCNH8 LMO3 ABCC6 FHIP1A SLC44A3

1.28e-0418811550d86044bc340e3efb90d0022dd299873639d831c
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

LMO3 NR6A1 CAPN8 SCN1A FHIP1A

1.28e-041881155707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellIPF-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

SLC9A9 POU2F2 PAPSS2 TBC1D8 NACC2

1.31e-0418911555c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

LMO3 CAPN13 CAPN8 KIAA1217 FHIP1A

1.31e-04189115584d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

LMO3 CAPN13 CAPN8 KIAA1217 FHIP1A

1.31e-041891155f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

OBSCN NLGN1 RYR2 KIAA1217 FHIP1A

1.31e-0418911550a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH8 LMO3 ABCC6 FHIP1A SLC44A3

1.34e-041901155c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCellILEUM-non-inflamed-(8)_Activated_fibroblasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

KIF23 MPDZ PAPSS2 PLEKHA8P1 NLGN4X

1.34e-04190115539fa110d19c97c7cac99f5fb91b26bc08e2f3b42
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH7 TBC1D8 SCGB2A1 PCM1 DEUP1

1.38e-041911155683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH8 LMO3 DNAH7 FHIP1A SLC44A3

1.38e-04191115560ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

LMO3 ADCY8 CAPN8 SCN1A FHIP1A

1.38e-041911155a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

LMO3 CAPN13 CAPN8 KIAA1217 FHIP1A

1.38e-04191115523776c7302cead3881b39127398f3b3e0d27885e
ToppCellIPF-Epithelial-Club|World / Disease state, Lineage and Cell class

LMO3 CAPN13 CAPN8 KIAA1217 FHIP1A

1.38e-0419111553c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LMO3 ABCC6 KIAA1217 FHIP1A SLC44A3

1.38e-041911155ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIF23 KCNH8 LMO3 FHIP1A SLC44A3

1.41e-04192115525378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

LMO3 ABCC6 CAPN8 KIAA1217 FHIP1A

1.41e-041921155499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

MPDZ LMO3 CAPN8 KIAA1217 FHIP1A

1.41e-0419211550644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCellControl-Epithelial-Club|Control / Disease state, Lineage and Cell class

LMO3 CAPN13 CAPN8 KIAA1217 FHIP1A

1.41e-041921155d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

LMO3 ADCY8 CAPN8 SCN1A FHIP1A

1.41e-04192115558c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

LMO3 ABCC6 CAPN8 KIAA1217 FHIP1A

1.41e-041921155efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH8 DNAH7 TBC1D8 FHIP1A SLC44A3

1.41e-041921155b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KCNH8 LMO3 NLGN4X FHIP1A SLC44A3

1.44e-041931155b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

LMO3 CAPN13 CAPN8 KIAA1217 FHIP1A

1.44e-0419311552bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NLGN1 NR6A1 DNAH7 FHIP1A SLC44A3

1.44e-04193115582e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NLGN1 NR6A1 DNAH7 FHIP1A SLC44A3

1.44e-0419311553866667dd221612589ae50f5c52f73a183a49ce6
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LMO3 ABCC6 KIAA1217 FHIP1A SLC44A3

1.44e-041931155a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

POU2F1 YTHDC2 FAM186A PCM1

1.47e-0410311541b2edf25d6b845e7c07470b2a034654d63917c01
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGALS9C LGALS9B CAPN8 SCGB2A1 TTC39A

1.48e-04194115549cc5f5de4380302100e8cd937f08abe317ac75e
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGALS9C LGALS9B CAPN8 SCGB2A1 TTC39A

1.48e-041941155fb935df966c451e659b8bde281f8aebcb632f6cf
ToppCell10x5'-blood-Lymphocytic_NK-NK_CD16|blood / Manually curated celltypes from each tissue

LGALS9B ENC1 CST7 HNRNPL LGALS9

1.48e-041941155c34a32f1cfe3e597cb0f91ba5bdd3e114e9f3d2e
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LMO3 NR6A1 CAPN8 SCN1A FHIP1A

1.48e-04194115553f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EVC NR6A1 DNAH7 FHIP1A SLC44A3

1.48e-04194115593c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NLGN1 TEX15 KLHL3 ARHGAP28 GNAO1

1.48e-04194115599577a5a631e607b5abe7a1b0d8d6a5eabe50196
Diseaseautism spectrum disorder (implicated_via_orthology)

SLC9A9 NLGN4Y NLGN1 NLGN3 NLGN4X SCN1A NLGN2

1.71e-061521107DOID:0060041 (implicated_via_orthology)
DiseaseAutism Spectrum Disorders

SIN3A RYR2 NLGN3 NLGN4X SCN1A

1.70e-05851105C1510586
Diseaseimmune system disease (implicated_via_orthology)

POU2F1 POU2F2

4.12e-0531102DOID:2914 (implicated_via_orthology)
DiseaseEPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 1

SCN1A GNAO1

2.05e-0461102C3463992
Diseaseinsomnia measurement

LMO3 NLGN1 TEX15 FAM222B SERPINC1 RORB GNAO1 PCDH1

2.61e-044431108EFO_0007876
DiseaseNephronophthisis, familial juvenile

NPHP4 WDR19

2.86e-0471102C1855681
DiseaseSenior-Loken syndrome (is_implicated_in)

NPHP4 WDR19

2.86e-0471102DOID:0050576 (is_implicated_in)
DiseaseRenal dysplasia and retinal aplasia

NPHP4 WDR19

2.86e-0471102cv:C0403553
Diseaseserum iron measurement

SCGN ADCY8 MYSM1 GNAO1

3.07e-04861104EFO_0006332
DiseaseX-linked infantile spasms

SCN1A GNAO1

3.80e-0481102C4552072
Diseaseautistic disorder (is_implicated_in)

SLC9A9 NLGN3 NLGN4X

5.21e-04421103DOID:12849 (is_implicated_in)
Diseasethyroid peroxidase antibody measurement, anti-thyroglobulin antibody measurement

TRPM6 PDE10A RORB

6.38e-04451103EFO_0005666, EFO_0009896
DiseaseCiliopathies

OFD1 EVC NPHP4 WDR19

7.79e-041101104C4277690
DiseaseRenal dysplasia and retinal aplasia (disorder)

NPHP4 WDR19

8.87e-04121102C0403553
Diseaseresponse to simvastatin, total cholesterol change measurement, response to fenofibrate

KCNH8 NLGN1 SCGN

9.22e-04511103EFO_0007806, GO_1901557, GO_1903491
DiseaseNephronophthisis

NPHP4 WDR19

1.05e-03131102C0687120
DiseaseNon-steroidal anti-inflammatory and antirheumatic product use measurement

STAT6 GNAO1

1.40e-03151102EFO_0009935
Diseaselevel of Phosphatidylcholine (16:0_16:0) in blood serum

SNX13 SMARCA4

1.40e-03151102OBA_2045067
DiseaseSjogren syndrome

IRAK1BP1 NACC2 GNAO1

1.48e-03601103EFO_0000699
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A GNAO1

1.60e-03161102C0393706
DiseaseAntihistamine use measurement

STAT6 GNAO1

1.81e-03171102EFO_0009943
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

KMT2B MED13

1.81e-03171102DOID:0060307 (is_implicated_in)
Diseasemagnesium measurement

TRPM6 PAPSS2 ADCY8

1.94e-03661103EFO_0004845
Diseasenephrotic syndrome (is_marker_for)

NR3C1 SERPINC1

2.03e-03181102DOID:1184 (is_marker_for)
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

SCGN SNX13 SMARCA4 GNAO1

2.10e-031441104EFO_0004611, EFO_0020943
Diseaseurinary microalbumin measurement

MON2 YTHDC2

2.50e-03201102EFO_0010967
Diseasefibrinogen measurement, coronary artery disease

SCGN SNX13 SMARCA4 GNAO1

2.68e-031541104EFO_0001645, EFO_0004623
Diseasejuvenile idiopathic arthritis

SCGN NPHP4 GNAO1

2.70e-03741103EFO_0002609
DiseaseInfiltrating duct carcinoma of female breast

SMG1 MYLK4

2.76e-03211102C3165106
DiseaseAutistic Disorder

SLC9A9 NLGN1 NLGN3 NLGN4X PLA2G4A

3.00e-032611105C0004352
Diseaseanxiety disorder (implicated_via_orthology)

KDM3B SCN1A

3.03e-03221102DOID:2030 (implicated_via_orthology)
Diseaseeosinophilic esophagitis

SLC9A9 STAT6 TBC1D13 SCGB2A1

3.29e-031631104EFO_0004232
Diseasefrailty measurement

NLGN1 GNAO1

3.31e-03231102EFO_0009885
Diseasegamma-linolenic acid measurement

SNX13 SCGB2A1

3.60e-03241102EFO_0007762

Protein segments in the cluster

PeptideGeneStartEntry
QMRDEVFKSNLVCAF

ADCY8

706

P40145
AEYKQMQCDFQLLSE

CCDC7

301

Q96M83
VFNKFCLSNMTLLES

ABCA12

206

Q86UK0
EDFNLIVTNCMKYNA

BRPF3

656

Q9ULD4
SCQDFQQKFIAMFIC

CAPN13

316

Q6MZZ7
KFDGFNINTCREMIS

CAPN8

571

A6NHC0
CSRLQDKMNFDVSNL

ANKRD26

1041

Q9UPS8
ACNDTLQQLMEVFKF

SERPINC1

126

P01008
DSLEKCNLAMTQNYE

DEUP1

76

Q05D60
LRFLDYEMQNSNECK

NETO1

216

Q8TDF5
FEKSCQAMFQQINDS

EDC4

1126

Q6P2E9
ELTMFQNDFEKACQA

OFD1

241

O75665
MTKEECLQFTANALA

PSMB6

181

P28072
SVEKFNNCTNDMFLF

CST7

56

O76096
NNCTNDMFLFKESRI

CST7

61

O76096
KCKEMNADAVFAFQL

PAPSS2

396

O95340
FLCQKLNLANSETDM

LRRD1

781

A4D1F6
TFTEFGKMQNICNFL

IRAK1BP1

131

Q5VVH5
LVNENRFCNDAMKVA

LDOC1

76

O95751
FQSLDGIMFINKCAT

SPINK5

51

Q9NQ38
LCFLVQSSDFKVMVN

LGALS9C

101

Q6DKI2
LCFLVQSSDFKVMVN

LGALS9B

101

Q3B8N2
LCFLVQSSDFKVMVN

LGALS9

101

O00182
KECLAVMESYFNENQ

HMBOX1

276

Q6NT76
FNELAFFKLMQDLDN

PCM1

1681

Q15154
NVLDCNDNDPKFMLS

PCDH1

601

Q08174
TDENNFKMFAVFCAL

PDE10A

396

Q9Y233
LMNDIFNKECRQSLS

COPB1

626

P53618
EMNCKEDQFQLSLLA

COPB1

681

P53618
FQQACFREQSLAMLS

FAM222B

521

Q8WU58
SNQLEKMAFFQCREE

MYLK4

16

Q86YV6
ISRFEALNLSFKNMC

POU2F2

241

P09086
QKDTDLSKNLFFQCM

KDM3B

516

Q7LBC6
DKFFLKNNMILCQTD

LMO3

116

Q8TAP4
NLLNYCFQTFLDKTM

NR3C1

731

P04150
LRKCTFDMFNFLASQ

KMT2B

2516

Q9UMN6
MCFETLLQFSFSNKV

MON2

1581

Q7Z3U7
TELFPCNFSKNDVML

NLGN1

561

Q8N2Q7
DCLQSNEMVLQFLAF

NPHP4

636

O75161
ISRFEALNLSFKNMC

POU2F1

326

P14859
SFYQEKDMLSNCRQN

HOXC6

76

P09630
MLKSNDCLFSLENLF

HFM1

1

A2PYH4
DVAMCFIKNQAAFEQ

OBSCN

5766

Q5VST9
FNAKTISLLECFAQM

OR56B2P

96

Q8NGI1
LFPCNFSKNDVMLSA

NLGN3

541

Q9NZ94
ELFSCNFSKNDVMLS

NLGN4Y

506

Q8NFZ3
FENERNMFGKLSQLC

CCDC181

176

Q5TID7
NMFGKLSQLCISNDF

CCDC181

181

Q5TID7
QTVVFNCSDQLDFMA

DNAH1

1601

Q9P2D7
SLVQFMNSLEFCNAV

FHIP1A

281

Q05DH4
NCVDLMQAAEVFSQK

KLHL12

146

Q53G59
FSPMASQENCLEKFI

BICRAL

1041

Q6AI39
NAFFQECQKREKDMS

DOCK10

861

Q96BY6
SKDNRMSCTVNLLNF

DOCK2

1196

Q92608
MSCTVNLLNFYKDNN

DOCK2

1201

Q92608
KLESFFNCAAALMTL

DNAH7

356

Q8WXX0
QLQAFMDESTQCFQK

DSN1

301

Q9H410
TLLDFCDPDQMKFTQ

AGBL2

661

Q5U5Z8
LKTNFFATRNMCNEL

CBR3

111

O75828
QSKMNCDRVFNVFCL

HNRNPL

391

P14866
NNNTCKDFLIEAMKY

KLHL3

261

Q9UH77
FFMNSCNLEVKGTQL

SLC44A3

96

Q8N4M1
MCLSNFQTIRKNEDF

ENC1

171

O14682
MANIQHFLVDQFKCS

EVC

321

P57679
ALSMLNDELKCVNFQ

FAM186A

271

A6NE01
NCETDTLINYMAKFA

SEC24C

841

P53992
QENFLLQFKMDACST

SCGN

181

O76038
FNCNLNHLMSQDDIK

SACS

3391

Q9NZJ4
NFCEDTIFEMQLAAQ

RYR2

4191

Q92736
TDLFPCNFSKNDVML

NLGN2

516

Q8NFZ4
ELFSCNFSKNDVMLS

NLGN4X

506

Q8N0W4
YVFKSNDRNSMDIQC

KIF23

151

Q02241
FSMALCDQEKTFRQQ

PLA2G4A

146

P47712
NMNIKLTDFGFSCQL

PHKG1

161

Q16816
NEEYACMKAINFLNQ

NR6A1

386

Q15406
FLKTLEECMQIANAA

PLEKHA8P1

46

O95397
RDSNCNYEAFMNIIK

SNX13

281

Q9Y5W8
TKQLFEFMNFLAENV

SLC9A9

361

Q8IVB4
KMCLQTLQAADTQEF

TOP6BL

416

Q8N6T0
MFLSACLQTLFEQQN

ABCC6

356

O95255
MLQLTCFKDVDISNF

OR7E24

181

Q6IFN5
ESLMLFDSICNNKFF

GNAO1

246

P09471
TLFRNSCFSEDQMAK

SMG1

3066

Q96Q15
EKDVMLLCQNAQTFN

SMARCA4

1526

P51532
DKIMAELQAFQKCSF

KIAA1217

1131

Q5T5P2
ELQAFQKCSFMDVNS

KIAA1217

1136

Q5T5P2
ENCFKLMFIQSQGQV

SIN3A

1061

Q96ST3
IQFLVMSKCNNEAFT

WDR19

971

Q8NEZ3
ILSESVMNLFKDCNF

MED13

1076

Q9UHV7
QFMEFEKLSQFAAAL

SCN1A

1821

P35498
IAFPSDEDMCQKFLQ

CNBD2

476

Q96M20
IINMNLNKCDSAFDI

C12orf29

286

Q8N999
ELCSMFITNKNFQIL

NLRP9

621

Q7RTR0
MGTFCSVIKFENLQE

ZDHHC6

1

Q9H6R6
DSMCNEFSQIFQLCQ

XPO1

196

O14980
FLAENNKLCETVMAQ

VPS35L

856

Q7Z3J2
EIICMIQNTFNFSLK

TRPM6

346

Q9BX84
NAECVMLQNVSKESF

MPDZ

991

O75970
QNFQEEACFILDTMK

TFCP2

476

Q12800
AEAMGKFKQCFLNQS

SCGB2A1

56

O75556
FLAQKIFNDNSLSME

STAT6

476

P42226
ANRDAAQALMTFFNK

ARHGAP28

506

Q9P2N2
NMDQLIEFKAFVSCL

TBC1D8

891

O95759
NKMFEDSQDSCRNLV

SP100

86

P23497
EFAKRITGFMELCQN

RORB

286

Q92753
NFELAFTMAENLANC

SMTNL2

411

Q2TAL5
CFTNLMAEIRDNFIK

TBC1D13

261

Q9NVG8
AQLNLSNMKISAECF

ZBTB1

61

Q9Y2K1
ERAFCEKNFLSQATM

YTHDC2

916

Q9H6S0
TGEEIFNCINSFMQK

ZBED5

316

Q49AG3
FGQTFLQKSDLSMCQ

ZNF70

91

Q9UC06
CQMSQAVLDEDLFNF

ZSWIM3

351

Q96MP5
MDKFAEDLTNRCNVF

WASHC4

426

Q2M389
ELVQCQEKMASFSFL

TEX15

2101

Q9BXT5
DQCMTALDLFLTNQF

TTC39A

26

Q5SRH9
SLSQRVMCNDLFKVN

MYO18A

66

O95411
RFLDFKIQNMVGSCD

TBPL2

286

Q6SJ96
LFCQKRFDESMQVFA

VPS39

356

Q96JC1
AASYLQMNDVVNFCK

ZBTB8B

101

Q8NAP8
SCKFLFGVETNEQLM

KCNH8

66

Q96L42
CQNFAPSFKESEMNV

NACC2

421

Q96BF6
IQKNLNDNEMLFHSC

MYSM1

346

Q5VVJ2