Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium-dependent phospholipid binding	ANXA2 ANXA2P2 ANXA4 PCLO MCTP1	3.40e-05	60	123	5	GO:0005544
GeneOntologyMolecularFunction	bone sialoprotein binding	ANXA2 ANXA2P2	3.76e-05	2	123	2	GO:0044730
GeneOntologyMolecularFunction	phospholipase inhibitor activity	ANXA2 ANXA2P2 ANXA4	6.24e-05	13	123	3	GO:0004859
GeneOntologyMolecularFunction	modified amino acid binding	ANXA2 ANXA2P2 ANXA4 GSTM1 GSTM2 GSTM4	1.09e-04	122	123	6	GO:0072341
GeneOntologyMolecularFunction	suramin binding	RYR2 P2RX1	1.12e-04	3	123	2	GO:0043924
GeneOntologyMolecularFunction	lipase inhibitor activity	ANXA2 ANXA2P2 ANXA4	1.74e-04	18	123	3	GO:0055102
GeneOntologyMolecularFunction	glutathione binding	GSTM1 GSTM2 GSTM4	1.74e-04	18	123	3	GO:0043295
GeneOntologyMolecularFunction	histone H3K36 dimethyltransferase activity	NSD1 SMYD3	2.24e-04	4	123	2	GO:0140954
GeneOntologyMolecularFunction	oligopeptide binding	GSTM1 GSTM2 GSTM4	2.41e-04	20	123	3	GO:1900750
GeneOntologyMolecularFunction	phospholipase A2 inhibitor activity	ANXA2 ANXA2P2	3.72e-04	5	123	2	GO:0019834
GeneOntologyMolecularFunction	calmodulin binding	MYH6 MAP2 UBR4 OBSCN RYR2 MKNK1 SNTB1	5.63e-04	230	123	7	GO:0005516
GeneOntologyMolecularFunction	glutathione transferase activity	GSTM1 GSTM2 GSTM4	7.41e-04	29	123	3	GO:0004364
GeneOntologyBiologicalProcess	nitrobenzene metabolic process	GSTM1 GSTM2 GSTM4	8.65e-07	4	125	3	GO:0018916
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein particle receptor binding	ANXA2 ANXA2P2	3.64e-05	2	125	2	GO:1905597
GeneOntologyCellularComponent	myelin sheath adaxonal region	ANXA2 ANXA2P2 CNP	7.35e-06	7	126	3	GO:0035749
GeneOntologyCellularComponent	myelin sheath	ANXA2 ANXA2P2 EEF1A2 GSTM1 STXBP1 PRDX1 PARD3 CNP	5.21e-05	217	126	8	GO:0043209
GeneOntologyCellularComponent	nuclear periphery	STAG1 MAP2 ANXA2 ANXA2P2 TEP1 TENM1 EMD	8.09e-05	171	126	7	GO:0034399
GeneOntologyCellularComponent	cell cortex	ANXA2 ANXA2P2 PCLO NEDD4 GRIP1 STXBP1 EMD PARD3 MYL12B HCLS1	8.53e-05	371	126	10	GO:0005938
GeneOntologyCellularComponent	AnxA2-p11 complex	ANXA2 ANXA2P2	1.08e-04	3	126	2	GO:1990665
GeneOntologyCellularComponent	PCSK9-AnxA2 complex	ANXA2 ANXA2P2	1.08e-04	3	126	2	GO:1990667
GeneOntologyCellularComponent	Schmidt-Lanterman incisure	ANXA2 ANXA2P2 PARD3	1.37e-04	17	126	3	GO:0043220
GeneOntologyCellularComponent	compact myelin	ANXA2 ANXA2P2 PARD3	2.63e-04	21	126	3	GO:0043218
GeneOntologyCellularComponent	actomyosin	MYH6 HDAC4 ANXA2 ANXA2P2 MYL12B	7.18e-04	117	126	5	GO:0042641
GeneOntologyCellularComponent	sarcolemma	ANXA2 ANXA2P2 OBSCN RYR2 CLCN1 SNTB1	1.04e-03	190	126	6	GO:0042383
Domain	GST_mu	GSTM1 GSTM2 GSTM4	2.50e-06	5	119	3	IPR003081
Domain	GST_C	EPRS1 GSTM1 GSTM2 GSTM4	2.10e-05	26	119	4	IPR004046
Domain	GST_C	EPRS1 GSTM1 GSTM2 GSTM4	2.10e-05	26	119	4	PF00043
Domain	Glutathione-S-Trfase_C-like	EPRS1 GSTM1 GSTM2 GSTM4	1.08e-04	39	119	4	IPR010987
Domain	-	EPRS1 GSTM1 GSTM2 GSTM4	1.08e-04	39	119	4	1.20.1050.10
Domain	EF-hand_11	EFCAB6 MYL12B	1.20e-04	3	119	2	PF08976
Domain	EF_hand_DJBP	EFCAB6 MYL12B	1.20e-04	3	119	2	IPR015070
Domain	EFTu-like_2	EEF1A2 EFTUD2 EIF5B	1.92e-04	18	119	3	IPR004161
Domain	GTP_EFTU_D2	EEF1A2 EFTUD2 EIF5B	1.92e-04	18	119	3	PF03144
Domain	G_TR_2	EEF1A2 EFTUD2 EIF5B	1.92e-04	18	119	3	PS51722
Domain	TF_GTP-bd_dom	EEF1A2 EFTUD2 EIF5B	2.27e-04	19	119	3	IPR000795
Domain	GST_N	GSTM1 GSTM2 GSTM4	3.56e-04	22	119	3	PF02798
Domain	GST_NTER	GSTM1 GSTM2 GSTM4	3.56e-04	22	119	3	PS50404
Domain	Transl_B-barrel	EEF1A2 EFTUD2 EIF5B	6.60e-04	27	119	3	IPR009000
Domain	Glutathione_S-Trfase_N	GSTM1 GSTM2 GSTM4	6.60e-04	27	119	3	IPR004045
Domain	-	DHX33 TEP1 RRAGC DNAH1 EEF1A2 EFTUD2 IQCA1 EIF5B NAV1 DHX34 RAB26 HYDIN CNP	9.41e-04	746	119	13	3.40.50.300
Domain	P-loop_NTPase	MYH6 DHX33 TEP1 RRAGC DNAH1 EEF1A2 EFTUD2 IQCA1 EIF5B NAV1 DHX34 RAB26 HYDIN CNP	1.01e-03	848	119	14	IPR027417
Domain	-	C5orf63 GSTM1 GSTM2 GSTM4 PRDX1	1.11e-03	122	119	5	3.40.30.10
Domain	GST_CTER	GSTM1 GSTM2 GSTM4	1.31e-03	34	119	3	PS50405
Domain	Thioredoxin-like_fold	C5orf63 GSTM1 GSTM2 GSTM4 PRDX1	1.57e-03	132	119	5	IPR012336
Domain	GST_C_3	GSTM1 GSTM4	1.75e-03	10	119	2	PF14497
Domain	-	PCLO NEDD4 MCTP1 SYDE2 WWC1	2.59e-03	148	119	5	2.60.40.150
Domain	PDZ	PCLO GRIP1 FRMPD3 PARD3 SNTB1	2.82e-03	151	119	5	PS50106
Domain	PDZ	PCLO GRIP1 FRMPD3 PARD3 SNTB1	2.90e-03	152	119	5	IPR001478
Domain	G_TR_1	EEF1A2 EFTUD2	3.00e-03	13	119	2	PS00301
Domain	ANX	ANXA2 ANXA4	3.00e-03	13	119	2	SM00335
Domain	Annexin_repeat_CS	ANXA2 ANXA4	3.00e-03	13	119	2	IPR018252
Domain	Annexin	ANXA2 ANXA4	3.00e-03	13	119	2	PF00191
Domain	Annexin_repeat	ANXA2 ANXA4	3.00e-03	13	119	2	IPR018502
Domain	ANNEXIN	ANXA2 ANXA4	3.00e-03	13	119	2	PS00223
Domain	-	ANXA2 ANXA4	3.00e-03	13	119	2	1.10.220.10
Domain	Annexin	ANXA2 ANXA4	3.48e-03	14	119	2	IPR001464
Domain	C2_dom	PCLO NEDD4 MCTP1 SYDE2 WWC1	4.01e-03	164	119	5	IPR000008
Domain	DUF1605	DHX33 DHX34	5.14e-03	17	119	2	IPR011709
Domain	OB_NTP_bind	DHX33 DHX34	5.14e-03	17	119	2	PF07717
Domain	HA2	DHX33 DHX34	5.76e-03	18	119	2	SM00847
Domain	HA2	DHX33 DHX34	5.76e-03	18	119	2	PF04408
Domain	Helicase-assoc_dom	DHX33 DHX34	5.76e-03	18	119	2	IPR007502
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	EHBP1 EPRS1 MIA3 MAP2 ANXA2 ANXA2P2 PCLO UBR4 RANBP9 RYR2 PPM1G GSTM1 STXBP1 PI4KA RAB3GAP2 PRDX1 TENM1 NAV1 EMD POLD3 DNAJB2 MYL12B	1.42e-10	1139	126	22	36417873
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	PDXDC1 EPRS1 MIA3 ANXA2 ANXA4 PCLO UBR4 RPS14 ECPAS DNAH1 EEF1A2 EFTUD2 GSTM4 PRDX1 EIF5B HYDIN DISP1	6.06e-09	807	126	17	30575818
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	USP34 MIA3 MAP2 UBR4 PPM1G STXBP1 PI4KA RAB3GAP2 ANKRD12 KLHL12 EMD	2.85e-08	322	126	11	26514267
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	STAG1 MAP2 ANXA2 PCLO UBR4 ECPAS EEF1A2 GSTM2 GRIP1 RAB3GAP2 EIF5B NAV1 CNP	3.58e-08	498	126	13	36634849
Pubmed	Alternative mutations of a positively selected residue elicit gain or loss of functionalities in enzyme evolution.	GSTM1 GSTM2 GSTM4	4.64e-08	3	126	3	16549767
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	PDXDC1 USP34 EPRS1 MAP2 ANXA2 UBR4 RPS14 RANBP9 VPS26A ECPAS PPM1G EEF1A2 EFTUD2 TELO2 RAB3GAP2 GNPDA2 PRDX1 EIF5B IRF2BPL POLD3 PUS7	6.30e-08	1455	126	21	22863883
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ENOSF1 EHBP1 MIA3 HDAC4 MAP2 KIAA0232 ANXA4 OBSCN ECPAS TEP1 LRP8 DNAH1 EEF1A2 LUC7L PPARGC1B NAV1 RCOR3 ANKRD12 PARD3 SMYD3 AFF4	9.28e-08	1489	126	21	28611215
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	EHBP1 SLAIN2 KIAA0930 HDAC4 MAP2 KIAA0232 EEF1A2 NEDD4 GRIP1 LUC7L PI4KA SYDE2 RAB3GAP2 NAV1 NHS PARD3	9.80e-08	861	126	16	36931259
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	EPRS1 HDAC4 ANXA2 RPS14 RANBP9 DNAH1 EFTUD2 HOXA13 LUC7L PRDX1 EIF5B NHS RCOR3 EMD POLD3 PARD3 MYL12B AFF4 WWC1	1.26e-07	1247	126	19	27684187
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	PDXDC1 SLAIN2 USP34 EFCAB6 FERMT1 RPS14 RYR2 PPM1G DMXL1 EFTUD2 FAT1 PI4KA SYDE2 EMD PARD3	1.56e-07	777	126	15	35844135
Pubmed	The annexins: specific markers of midline structures and sensory neurons in the developing murine central nervous system.	ANXA2 ANXA2P2 ANXA4	1.85e-07	4	126	3	7706559
Pubmed	Hspb1 protects against severe acute pancreatitis by attenuating apoptosis and ferroptosis via interacting with Anxa2 to restore the antioxidative activity of Prdx1.	ANXA2 ANXA2P2 PRDX1	1.85e-07	4	126	3	38481805
Pubmed	The inhibitory glutathione transferase M2-2 binding site is located in divergent region 3 of the cardiac ryanodine receptor.	RYR2 GSTM1 GSTM2	1.85e-07	4	126	3	22406107
Pubmed	Molecular cloning and heterologous expression of an alternatively spliced human Mu class glutathione S-transferase transcript.	GSTM1 GSTM2 GSTM4	1.85e-07	4	126	3	8373352
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PDXDC1 EPRS1 KIAA0930 HDAC4 ANXA2 DPCD UBR4 RPS14 RANBP9 ECPAS EEF1A2 EFTUD2 LUC7L TELO2 MORF4L2 EIF2B1 RAB3GAP2 PARD3 SMYD3	1.97e-07	1284	126	19	17353931
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MIA3 HDAC4 UBR4 RANBP9 NSD1 ARMCX4 EEF1A2 NEDD4 EFTUD2 PI4KA PRDX1 NAV1 FRMPD3 PARD3 CNP AFF4	4.38e-07	963	126	16	28671696
Pubmed	Glutathione S-transferase variants and hypertension.	GSTM1 GSTM2 GSTM4	4.62e-07	5	126	3	18551009
Pubmed	Genetic variants in GSTM3 gene within GSTM4-GSTM2-GSTM1-GSTM5-GSTM3 cluster influence breast cancer susceptibility depending on GSTM1.	GSTM1 GSTM2 GSTM4	4.62e-07	5	126	3	19856098
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	EPRS1 TOPAZ1 PCLO UBR4 OBSCN RPS14 ECPAS EEF1A2 IGSF10 FREM2 PI4KA SYDE2 PRDX1 EMD	4.96e-07	736	126	14	29676528
Pubmed	Purification and characterization of eight glutathione S-transferase isoenzymes of hamster. Comparison of subunit composition of enzymes from liver, kidney, testis, pancreas and trachea.	GSTM1 GSTM2 GSTM4	9.21e-07	6	126	3	1530570
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	EPRS1 MAP2 ANXA2 ANXA2P2 OBSCN RPS14 GSTM1 STXBP1 PI4KA PRDX1 EMD MYL12B	1.07e-06	564	126	12	21565611
Pubmed	CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.	EPRS1 ANXA2 RPS14 ECPAS PPM1G TELO2 PRDX1 EIF5B EMD CNP	3.15e-06	418	126	10	35338135
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	PDXDC1 EHBP1 LRP8 GRIP1 STXBP1 PI4KA NHS PARD3 SNTB1 CNP	3.36e-06	421	126	10	36976175
Pubmed	Developmental regulation of various annexins in the embryonic palate of the mouse: dexamethasone affects expression of annexin-1.	ANXA2 ANXA2P2 ANXA4	3.84e-06	9	126	3	8719346
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	EPRS1 MAK ANXA2 RPS14 RANBP9 PPM1G EEF1A2 EFTUD2 GSTM1 GSTM2 GSTM4 LUC7L MORF4L2 EIF2B1 PRDX1 MYL12B	4.49e-06	1153	126	16	29845934
Pubmed	An N-terminal motif unique to primate tau enables differential protein-protein interactions.	EEF1A2 GSTM1 GSTM2 STXBP1 PRDX1 CNP	4.98e-06	119	126	6	29382714
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	KIAA0930 MIA3 HDAC4 DPCD ECPAS GRIP1 NAV1 PARD3 SNTB1 WWC1	5.58e-06	446	126	10	24255178
Pubmed	USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.	KIAA0930 ANXA2 RPS14 EFTUD2 PTPRK TELO2 PRDX1 EMD POLD3 DNAJB2 CNP	7.12e-06	565	126	11	33567341
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	SLAIN2 STAG1 ANXA2 UBR4 RANBP9 EFTUD2 NFIL3 KIAA2012	7.15e-06	272	126	8	31010829
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	ANXA2 ANXA4 UBR4 RPS14 VPS26A ECPAS PPM1G RRAGC EFTUD2 LUC7L EIF5B IRF2BPL EMD DNAJB2 MYL12B CNP PUS7	9.34e-06	1367	126	17	32687490
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	EPRS1 ARID4A ANXA2 ANXA2P2 RPS14 NSD1 EEF1A2 EFTUD2 HOXA13 PRDX1 EIF5B EMD MYL12B AFF4	9.95e-06	954	126	14	36373674
Pubmed	MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer.	ANXA2 ANXA2P2 EFTUD2 GSTM2 MORF4L2 PRDX1 EMD CNP	1.06e-05	287	126	8	36180891
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	EHBP1 EPRS1 ANXA2 RPS14 ECPAS PPM1G GRIP1 RAB3GAP2 EIF5B EMD PARD3 CNP	1.09e-05	708	126	12	39231216
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	PDXDC1 USP34 UBR4 RANBP9 VPS26A ECPAS PPM1G PTPRK TELO2 EMD SNTB1 CNP PUS7 WWC1	1.25e-05	974	126	14	28675297
Pubmed	Structure of human glutathione S-transferase class Mu genes.	GSTM2 GSTM4	1.30e-05	2	126	2	2006920
Pubmed	Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy.	ANXA2 ANXA2P2	1.30e-05	2	126	2	19536308
Pubmed	Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion.	GSTM1 GSTM4	1.30e-05	2	126	2	3174634
Pubmed	Annexin A2 modulates radiation-sensitive transcriptional programming and cell fate.	ANXA2 ANXA2P2	1.30e-05	2	126	2	23148505
Pubmed	ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.	ANXA2 ANXA2P2	1.30e-05	2	126	2	38290972
Pubmed	The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats.	ANXA2 ANXA2P2	1.30e-05	2	126	2	3013423
Pubmed	Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis.	ANXA2 ANXA2P2	1.30e-05	2	126	2	35064931
Pubmed	Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.	ANXA2 ANXA2P2	1.30e-05	2	126	2	28130864
Pubmed	Functional compensation of glutathione S-transferase M1 (GSTM1) null by another GST superfamily member, GSTM2.	GSTM1 GSTM2	1.30e-05	2	126	2	24048194
Pubmed	Localization of annexin II in the paranodal regions and Schmidt-Lanterman incisures in the peripheral nervous system.	ANXA2 ANXA2P2	1.30e-05	2	126	2	17549680
Pubmed	Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice.	ANXA2 ANXA2P2	1.30e-05	2	126	2	39384746
Pubmed	Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.	ANXA2 ANXA2P2	1.30e-05	2	126	2	20826156
Pubmed	Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.	ANXA2 ANXA2P2	1.30e-05	2	126	2	27468426
Pubmed	Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.	ANXA2 ANXA2P2	1.30e-05	2	126	2	19841537
Pubmed	Identification of residues in glutathione transferase capable of driving functional diversification in evolution. A novel approach to protein redesign.	GSTM1 GSTM2	1.30e-05	2	126	2	12486119
Pubmed	Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice.	ANXA2 ANXA2P2	1.30e-05	2	126	2	27389701
Pubmed	Quantitative assessment of the effect of glutathione S-transferase genes GSTM1 and GSTT1 on hepatocellular carcinoma risk.	GSTM1 GSTM2	1.30e-05	2	126	2	24399650
Pubmed	Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation.	ANXA2 ANXA2P2	1.30e-05	2	126	2	17360942
Pubmed	Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina.	ANXA2 ANXA2P2	1.30e-05	2	126	2	19587120
Pubmed	The redox state of cytochrome c modulates resistance to methotrexate in human MCF7 breast cancer cells.	GSTM1 GSTM2	1.30e-05	2	126	2	23675469
Pubmed	Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate.	ANXA2 ANXA2P2	1.30e-05	2	126	2	19022301
Pubmed	Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.	ANXA2 ANXA2P2	1.30e-05	2	126	2	38253182
Pubmed	Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis.	ANXA2 ANXA2P2	1.30e-05	2	126	2	22185818
Pubmed	A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events.	ANXA2 ANXA2P2	1.30e-05	2	126	2	21486955
Pubmed	Lipid raft endocytosis and exosomal transport facilitate extracellular trafficking of annexin A2.	ANXA2 ANXA2P2	1.30e-05	2	126	2	21737841
Pubmed	Human genes for glutathione S-transferases.	GSTM1 GSTM2	1.30e-05	2	126	2	6500576
Pubmed	Regulation of the low-dose radiation paracrine-specific anchorage-independent growth response by annexin A2.	ANXA2 ANXA2P2	1.30e-05	2	126	2	19580511
Pubmed	Cloning and expression of a novel Mu class murine glutathione transferase isoenzyme.	GSTM2 GSTM4	1.30e-05	2	126	2	12069689
Pubmed	Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth.	ANXA2 ANXA2P2	1.30e-05	2	126	2	36739096
Pubmed	Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.	ANXA2 ANXA2P2	1.30e-05	2	126	2	22517898
Pubmed	Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.	ANXA2 ANXA2P2	1.30e-05	2	126	2	30462534
Pubmed	Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis.	ANXA2 ANXA2P2	1.30e-05	2	126	2	38092984
Pubmed	Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.	ANXA2 ANXA2P2	1.30e-05	2	126	2	21572519
Pubmed	Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice.	ANXA2 ANXA2P2	1.30e-05	2	126	2	21788340
Pubmed	The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis of Cryptococcus neoformans and Impacts Survival in Fungal Infection.	ANXA2 ANXA2P2	1.30e-05	2	126	2	27371724
Pubmed	Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice.	ANXA2 ANXA2P2	1.30e-05	2	126	2	31817350
Pubmed	ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.	ANXA2 ANXA2P2	1.30e-05	2	126	2	37832154
Pubmed	Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice.	ANXA2 ANXA2P2	1.30e-05	2	126	2	30902828
Pubmed	Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis.	ANXA2 ANXA2P2	1.30e-05	2	126	2	24742684
Pubmed	Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.	ANXA2 ANXA2P2	1.30e-05	2	126	2	32687500
Pubmed	Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.	ANXA2 ANXA2P2	1.30e-05	2	126	2	22453828
Pubmed	Impact of domain interchange on conformational stability and equilibrium folding of chimeric class micro glutathione transferases.	GSTM1 GSTM2	1.30e-05	2	126	2	12192076
Pubmed	Prognostic significance of annexin A2 and annexin A4 expression in patients with cervical cancer.	ANXA2 ANXA4	1.30e-05	2	126	2	27402115
Pubmed	Agents that bind annexin A2 suppress ocular neovascularization.	ANXA2 ANXA2P2	1.30e-05	2	126	2	20607799
Pubmed	A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study.	ANXA2 ANXA2P2	1.30e-05	2	126	2	31253864
Pubmed	Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo.	ANXA2 ANXA2P2	1.30e-05	2	126	2	19628708
Pubmed	Annexin A2 binds to the localization signal in the 3' untranslated region of c-myc mRNA.	ANXA2 ANXA2P2	1.30e-05	2	126	2	15654879
Pubmed	Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis.	ANXA2 ANXA2P2	1.30e-05	2	126	2	20847146
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	PDXDC1 EPRS1 ANXA2 ANXA2P2 UBR4 RPS14 DHX33 PPM1G EEF1A2 EFTUD2 TELO2 PRDX1 EMD POLD3 DNAJB2 CNP	1.32e-05	1257	126	16	37317656
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	EPRS1 MYH6 MAP2 ANXA2 ANXA2P2 PCLO RPS14 EEF1A2 GSTM1 STXBP1 MORF4L2 PI4KA PRDX1 NAV1 HADH MYL12B CNP	1.68e-05	1431	126	17	37142655
Pubmed	Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves.	ANXA2 ANXA2P2 PARD3	2.05e-05	15	126	3	20237282
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	STAG1 RPS14 DMXL1 LUC7L PRDX1	2.20e-05	92	126	5	15840729
Pubmed	p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.	EPRS1 DHX33 EIF5B PARD3 SNTB1 CNP	2.60e-05	159	126	6	30581152
Pubmed	140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry.	MAP2 ANXA2 ANXA2P2 STXBP1 PI4KA CNP	2.99e-05	163	126	6	16512683
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	EPRS1 UBR4 FERMT1 RPS14 RANBP9 VPS26A DHX33 EFTUD2 PI4KA PRDX1 EIF5B EMD POLD3 PARD3 DHX34 CNP	3.21e-05	1353	126	16	29467282
Pubmed	CHFR regulates chemoresistance in triple-negative breast cancer through destabilizing ZEB1.	RPS14 PPM1G EEF1A2 PRDX1 EMD	3.46e-05	101	126	5	34462429
Pubmed	STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.	ANXA2 ANXA2P2	3.90e-05	3	126	2	35098646
Pubmed	The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.	ANXA2 ANXA2P2	3.90e-05	3	126	2	35413401
Pubmed	Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases.	ANXA2 ANXA2P2	3.90e-05	3	126	2	28694388
Pubmed	High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2.	ANXA2 ANXA2P2	3.90e-05	3	126	2	27470587
Pubmed	Altered growth characteristics of skin fibroblasts from wild-derived mice, and genetic loci regulating fibroblast clone size.	GSTM2 GSTM4	3.90e-05	3	126	2	16842493
Pubmed	Annexins--unique membrane binding proteins with diverse functions.	ANXA2 ANXA2P2	3.90e-05	3	126	2	15169834
Pubmed	The structure of two murine class-mu glutathione transferase genes coordinately induced by butylated hydroxyanisole.	GSTM1 GSTM4	3.90e-05	3	126	2	8512323
Pubmed	Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9.	ANXA2 ANXA2P2	3.90e-05	3	126	2	24808179
Pubmed	The Annexin a2 Promotes Development in Arthritis through Neovascularization by Amplification Hedgehog Pathway.	ANXA2 ANXA2P2	3.90e-05	3	126	2	26963384
Pubmed	Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage.	GSTM1 GSTM2	3.90e-05	3	126	2	32574561
Interaction	SNCA interactions	STAG1 MAP2 ANXA2 PCLO UBR4 ECPAS EEF1A2 NEDD4 EFTUD2 GSTM2 GRIP1 LUC7L RAB3GAP2 PRDX1 EIF5B NAV1 CNP HCLS1	3.10e-07	716	122	18	int:SNCA
Interaction	AGR2 interactions	PDXDC1 EPRS1 MIA3 HDAC4 ANXA2 ANXA4 PCLO UBR4 RPS14 NSD1 ECPAS DNAH1 EEF1A2 EFTUD2 GSTM4 PRDX1 EIF5B HYDIN DISP1	3.36e-06	934	122	19	int:AGR2
Cytoband	1q41	EPRS1 MIA3 RAB3GAP2 DISP1	3.42e-05	66	126	4	1q41
Cytoband	Ensembl 112 genes in cytogenetic band chr1q41	EPRS1 MIA3 RAB3GAP2 DISP1	1.31e-04	93	126	4	chr1q41
GeneFamily	Glutathione S-transferases	GSTM1 GSTM2 GSTM4	1.66e-04	25	78	3	567
GeneFamily	PDZ domain containing	PCLO GRIP1 FRMPD3 PARD3 SNTB1	5.07e-04	152	78	5	1220
GeneFamily	Annexins\|Endogenous ligands	ANXA2 ANXA4	1.39e-03	13	78	2	404
GeneFamily	DEAH-box helicases	DHX33 DHX34	2.12e-03	16	78	2	500
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	MIA3 MAP2 ARID4A PCLO DHX33 RYR2 EEF1A2 GRIP1 LUC7L PPARGC1B STXBP1 PTPRK TENM1 NAV1 IRF2BPL ANKRD12 FRMPD3 HYDIN CNR1	1.27e-06	1106	125	19	M39071
Coexpression	MURARO_PANCREAS_BETA_CELL	SLAIN2 USP34 EPRS1 MIA3 MAP2 RBBP8 PCLO ECPAS RRAGC STXBP1 PI4KA RCOR3 ANKRD12 KLHL12 HADH CNP AFF4	2.67e-06	946	125	17	M39169
Coexpression	TRAVAGLINI_LUNG_CILIATED_CELL	ENOSF1 MAK EFCAB6 ANXA2 KIAA0232 ANXA4 DPCD DNAH1 IQCA1 MORF4L2 PRDX1 DLEC1 HADH POLD3 KIAA2012 HYDIN CTSS WWC1	4.47e-06	1093	125	18	M41649
Coexpression	GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_UP	ANXA4 UBR4 RANBP9 VPS26A PI4KA PRDX1 DNAJB2 CNP	5.48e-06	200	125	8	M7135
Coexpression	GSE21380_NON_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN	SLAIN2 USP34 ARID4A VPS26A EIF5B RP2 POLD3 MAP2K6	5.48e-06	200	125	8	M7505
Coexpression	GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_4H_UP	EPRS1 MIA3 C5orf63 HOXA13 NFIL3 EMD DNAJB2 MYL12B	5.48e-06	200	125	8	M8705
Coexpression	FONTAINE_FOLLICULAR_THYROID_ADENOMA_DN	EPRS1 MAP2 IGSF10 TENM1 HCLS1	2.15e-05	70	125	5	M5370
Coexpression	GSE27786_BCELL_VS_NEUTROPHIL_UP	USP34 DHX33 PPM1G EFTUD2 LUC7L PPARGC1B GNPDA2	5.06e-05	200	125	7	M4813
Coexpression	KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3	ANXA2 ANXA4 FERMT1 NEDD4 FAT1 PTPRK NFIL3 RAD1 PRDX1 NHS IRF2BPL LRRC37B DNAJB2 WWC1	5.13e-05	843	125	14	M2356
Coexpression	JIANG_TIP30_TARGETS_UP	ANXA2 BCL6 PPARGC1B NFIL3	6.89e-05	46	125	4	M12641
CoexpressionAtlas	Myeloid Cells, DC.103+11b-.SI, CD45+ MHCII+ CD11c-hi CD103+ CD11b-, Small Intestine, avg-4	KIAA0930 ANXA4 BCL6 ITGAX MCTP1 CPQ NFIL3 NAV1 RP2 MAP2K6 CTSS	9.41e-06	372	121	11	GSM854251_500
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAK ANXA2 ANXA4 ITGAX RRAGC LRP8 PPARGC1B DLEC1 CTSS	1.81e-09	176	125	9	b0b87eebcf5c994386b39ca607e17f10e9d9de74
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFCAB6 PCLO OBSCN RYR2 DNAH1 FREM2 FAT1 TENM1 HYDIN	2.67e-09	184	125	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFCAB6 PCLO OBSCN RYR2 DNAH1 FREM2 FAT1 TENM1 HYDIN	2.67e-09	184	125	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFCAB6 PCLO OBSCN RYR2 DNAH1 FREM2 FAT1 TENM1 HYDIN	2.67e-09	184	125	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RBBP8 PCLO GRIP1 FREM2 FAT1 NHS PARD3 WWC1 SLC44A3	4.25e-09	194	125	9	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ENOSF1 EHBP1 GRIP1 PTPRK NHS PARD3 HYDIN WWC1	5.71e-08	186	125	8	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	P15-Epithelial-airway_epithelial_cell-club_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MYH6 MAK EFCAB6 FERMT1 DNAH1 IQCA1 KIAA2012 HYDIN	5.95e-08	187	125	8	a70aaae32426e9ddb1cbfbd0e0db24ccc96b9f40
ToppCell	P15-Epithelial-airway_epithelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MYH6 MAK EFCAB6 FERMT1 DNAH1 IQCA1 KIAA2012 HYDIN	6.20e-08	188	125	8	e3e71c0f2e374330620cb4d27638953ffa9f5298
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 PTPRK IQCA1 NHS PARD3 HYDIN WWC1 SLC44A3	6.46e-08	189	125	8	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRIP1 FAT1 PTPRK NHS PARD3 HYDIN WWC1 SLC44A3	7.01e-08	191	125	8	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ENOSF1 PCLO GRIP1 FAT1 NHS PARD3 WWC1 SLC44A3	7.60e-08	193	125	8	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ENOSF1 ANXA4 GRIP1 FAT1 PTPRK NHS PARD3 WWC1	7.90e-08	194	125	8	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RBBP8 PCLO GRIP1 FREM2 FAT1 HYDIN WWC1 SLC44A3	7.90e-08	194	125	8	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	E18.5-Immune-Immune_Myeloid-DC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TEP1 ITGAX MCTP1 RP2 RAB26 CTSS HCLS1	3.54e-07	160	125	7	9f1fec2cf565193c73cc3c8a4f0476e57478e3b8
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAG1 FAM3D RYR2 EEF1A2 TENM1 ANKRD12 CNGA1	6.47e-07	175	125	7	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO FAM3D RYR2 EEF1A2 STXBP1 ANKRD12 CNR1	7.82e-07	180	125	7	f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RBBP8 GRIP1 FREM2 GRHL1 FAT1 PTPRK WWC1	9.06e-07	184	125	7	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EFCAB6 BCL6 TENM1 NHS HYDIN SNTB1 WWC1	1.01e-06	187	125	7	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	RYR2 EEF1A2 GRIP1 STXBP1 TENM1 ANKRD12 RAB26	1.12e-06	190	125	7	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	Ciliated-cil-3\|World / Class top	MAK DPCD DNAH1 IQCA1 DLEC1 KIAA2012 HYDIN	1.20e-06	192	125	7	4989ebb8812b8af1870599acd932849122c05a29
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PCLO GRIP1 FREM2 FAT1 NHS HYDIN WWC1	1.38e-06	196	125	7	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RBBP8 GRIP1 FAT1 NHS PARD3 HYDIN WWC1	1.43e-06	197	125	7	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANXA2 PCLO FAM3D GRIP1 PTPRK WWC1 SLC44A3	1.58e-06	200	125	7	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIAA0930 ITGAX PPARGC1B MCTP1 P2RX1 CTSS HCLS1	1.58e-06	200	125	7	fc061de0db2e8b5ca47f5e2a1e861018e7f1b582
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	OBSCN DNAH1 MCTP1 IQCA1 DLEC1 RAB26	4.71e-06	153	125	6	b37a1ecad389d2848b8ca4d287823e8048207420
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARID4A BCL6 ITGAX MCTP1 CTSS HCLS1	5.88e-06	159	125	6	807ee55fe0d3645fbfb98f641dd0a0555b847cf5
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH6 OBSCN EEF1A2 FREM2 FAT1 MAP2K6	7.78e-06	167	125	6	91b14df450bfb6a2b406c88f8c75cd51eeb9e82b
ToppCell	droplet-Heart-4Chambers-21m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 OBSCN RYR2 EEF1A2 GSTM1 GSTM2	9.84e-06	174	125	6	f098778ea74012861ec74b425e45776a31f67679
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 STAG1 NSD1 RYR2 NEDD4 IGSF10	1.05e-05	176	125	6	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GRIP1 FAT1 NHS PARD3 HYDIN WWC1	1.12e-05	178	125	6	544379f5a6145429762258d426b876bb36c112f5
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GRIP1 GRHL1 PTPRK IQCA1 PARD3 WWC1	1.12e-05	178	125	6	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PCLO GRIP1 FAT1 TENM1 NHS WWC1	1.19e-05	180	125	6	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	droplet-Liver-LIVER-NPC-1m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GC GSTM1 GSTM2 GSTM4 PRDX1 HADH	1.23e-05	181	125	6	48d28eafbb5f4b141deeb0bf020dfca39e7be7a5
ToppCell	droplet-Liver-LIVER-NPC-1m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GC GSTM1 GSTM2 GSTM4 PRDX1 HADH	1.23e-05	181	125	6	0a44781cc34535f061812d1370f748b7bbdef17b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 IQCA1 PARD3 HYDIN SNTB1 WWC1	1.23e-05	181	125	6	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	GRIP1 FREM2 GRHL1 STXBP1 PTPRK PARD3	1.23e-05	181	125	6	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RBBP8 FAM3D GRIP1 GRHL1 FAT1 WWC1	1.27e-05	182	125	6	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	severe-Myeloid-Neutrophils_1\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ITGAX CPQ NHS IRF2BPL DHX34 CTSS	1.31e-05	183	125	6	60a6112aa4fc4f5debda4c7e81b37539ba2e4e6e
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FERMT1 FAM3D FREM2 IQCA1 TENM1 SLC44A3	1.31e-05	183	125	6	2df1611c8acccb2a6f233d3d68bd9df2381a7278
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GRIP1 FAT1 TENM1 NHS HYDIN WWC1	1.31e-05	183	125	6	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FERMT1 FAM3D FREM2 IQCA1 TENM1 SLC44A3	1.35e-05	184	125	6	6388c47b7f1d8203e3069eba0e74107256dcae51
ToppCell	droplet-Heart-4Chambers-18m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FERMT1 FAM3D FREM2 IQCA1 TENM1 SLC44A3	1.35e-05	184	125	6	d83ae1dc64aa1b27d3b524c137567418cc0ff8c6
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GRIP1 GRHL1 FAT1 PTPRK PARD3 WWC1	1.39e-05	185	125	6	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NEDD4 FAT1 IQCA1 NHS PARD3 HYDIN	1.44e-05	186	125	6	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BCL6 TENM1 NHS HYDIN SNTB1 WWC1	1.44e-05	186	125	6	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RBBP8 BCL6 TENM1 NHS HYDIN WWC1	1.53e-05	188	125	6	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BCL6 FAT1 PARD3 HYDIN SNTB1 WWC1	1.67e-05	191	125	6	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	Myeloid-Myeloid-B_(Activated_Macrophage)\|Myeloid / shred on cell class and cell subclass (v4)	ANXA2 ANXA4 ITGAX RRAGC PRDX1 EIF5B	1.67e-05	191	125	6	7bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAK FAM3D DNAH1 IQCA1 KIAA2012 HYDIN	1.67e-05	191	125	6	96483adb97c81208aa513782550acd8a08b63866
ToppCell	droplet-Heart-nan-24m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EHBP1 MYH6 OBSCN RYR2 EEF1A2 FREM2	1.72e-05	192	125	6	f6a4e348406a852ace9fb21db8fbdff539217645
ToppCell	PCW_10-12-Hematologic_ErythroMegGranulo-Hem_Granulocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TRGC2 ITGAX MCTP1 P2RX1 CTSS HCLS1	1.72e-05	192	125	6	0ba5729a890bfba5db567cd0eec7924cd1991ac3
ToppCell	droplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EHBP1 MYH6 OBSCN RYR2 EEF1A2 FREM2	1.72e-05	192	125	6	1a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GSTM1 GSTM2 IGSF10 IQCA1 DLEC1 HYDIN	1.77e-05	193	125	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	droplet-Bladder-nan-3m-Epithelial-bladder_urothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FERMT1 FAM3D GSTM1 GSTM4 GRHL1 PARD3	1.77e-05	193	125	6	ee91a796d0f6d4cee7a93a525689e716fdceeda5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ENOSF1 PCLO GRIP1 NHS WWC1 SLC44A3	1.77e-05	193	125	6	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0930 TEP1 GSTM1 PRDX1 CTSS SMYD3	1.77e-05	193	125	6	5a201ee6f132357c9aacfbad3ae56ed9854c25fd
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA4 NEDD4 CPQ MORF4L2 NFIL3 AFF4	1.88e-05	195	125	6	4d63e0dca30ae57960459d2fbcba09122273e37b
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	ITGAX MCTP1 CPQ CTSS SNTB1 HCLS1	1.88e-05	195	125	6	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RBBP8 PCLO GRIP1 NHS PARD3 WWC1	1.88e-05	195	125	6	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA4 NEDD4 CPQ MORF4L2 NFIL3 AFF4	1.88e-05	195	125	6	661af601a3561fe3aacf2444ad7b8927fa88b48a
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIA3 PCLO NSD1 STXBP1 HADH AFF4	1.88e-05	195	125	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAM3D GRIP1 GRHL1 FAT1 NHS WWC1	1.88e-05	195	125	6	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GRIP1 GRHL1 FAT1 IQCA1 NHS WWC1	2.04e-05	198	125	6	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	control-Epithelial-Secretory\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PDXDC1 MIA3 NSD1 BCL6 FAM3D PTPRK	2.10e-05	199	125	6	3d01f90ffd271ca00129192787e4921bdca7e01e
ToppCell	Striatum-Neuronal\|Striatum / BrainAtlas - Mouse McCarroll V32	PCLO EEF1A2 STXBP1 PI4KA TENM1 ANKRD12	2.16e-05	200	125	6	c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GRIP1 FAT1 NHS FRMPD3 PARD3 CNR1	2.16e-05	200	125	6	d0167f96314be78b6d867bbcc6e4396071d931b8
ToppCell	Neuronal-Inhibitory-iA\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GRIP1 FAT1 NHS FRMPD3 PARD3 CNR1	2.16e-05	200	125	6	5ef4a3dc18a44292184a59ced916183c0699b01e
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	LRP8 NEDD4 GRIP1 TENM1 NHS PARD3	2.16e-05	200	125	6	107854f4855fc99c9f7e737eb246f0d868e6c5fd
ToppCell	Club_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	FERMT1 FAM3D GRHL1 FAT1 RAB26	5.95e-05	147	125	5	5a824c89e4d045af465d7333275f8191fb29b041
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM2 FREM2 P2RX1 RAB26 SNTB1	7.19e-05	153	125	5	39ac25c48e73538f1c10f37bea386e0e88d3e8d0
ToppCell	Control-Epithelial_airway-Ciliated_cells-Ciliated\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAK DNAH1 DLEC1 KIAA2012 HYDIN	7.42e-05	154	125	5	4e3bc24043144143842627cacf6f90dda2228910
ToppCell	Control-Epithelial_airway-Ciliated_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAK DNAH1 DLEC1 KIAA2012 HYDIN	7.42e-05	154	125	5	7556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GRIP1 SYDE2 NHS FRMPD3 CNR1	7.65e-05	155	125	5	105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC1\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BCL6 ITGAX MCTP1 CTSS HCLS1	8.63e-05	159	125	5	7bb76324d2026d4bd348126cb169c8411f0d7145
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TOPAZ1 RYR2 MKNK1 P2RX1 RAB26	9.15e-05	161	125	5	b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TOPAZ1 RYR2 MKNK1 P2RX1 RAB26	9.15e-05	161	125	5	f7a89c481f789f624102857be722c95fbeb47595
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WNT3 FREM2 TENM1 CNGA1 HYDIN	9.42e-05	162	125	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	-Hematopoietic_Mast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANXA4 MCTP1 P2RX1	9.79e-05	32	125	3	ca3d87cac849c1b713acd984626f214f5c8e1433
ToppCell	-Hematopoietic_Mast-Mast_cells-Mast-cells\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANXA4 MCTP1 P2RX1	9.79e-05	32	125	3	c6b707107c661f81e5afa945dd62b37a73bfadf9
ToppCell	-Hematopoietic_Mast-Mast_cells\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANXA4 MCTP1 P2RX1	9.79e-05	32	125	3	de636b6fbdc9368ef6ce7157acbf84e28330cd94
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM3D DNAH1 FREM2 GRHL1 KIAA2012	9.98e-05	164	125	5	e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITGAX MCTP1 RP2 RAB26 CTSS	1.12e-04	168	125	5	93b7138f17aa14a6398c9b4ea7237781a0e19a66
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITGAX MCTP1 RP2 RAB26 CTSS	1.12e-04	168	125	5	e393553208617a023f1646169c892a87c95db3f5
ToppCell	ASK428-Immune-Mast_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	FAT1 P2RX1 TENM1 NAV1 SMYD3	1.12e-04	168	125	5	c399fcb4d1d0be48026c2ecabc34a5935e7adf73
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GRIP1 FAT1 NHS HYDIN WWC1	1.12e-04	168	125	5	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C5orf63 ITGAX PPARGC1B CTSS DISP1	1.12e-04	168	125	5	c3d2d573f21350a4a674faff30b06ff644d00ac3
ToppCell	droplet-Lung-nan-3m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKNK1 GSTM4 P2RX1 CNGA1 HYDIN	1.15e-04	169	125	5	da607c1d068038d5a3d1117f6aa6e4c6f3552e97
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ENOSF1 MAK EFCAB6 DNAH1 HYDIN	1.15e-04	169	125	5	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	droplet-Lung-nan-3m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKNK1 GSTM4 P2RX1 CNGA1 HYDIN	1.15e-04	169	125	5	a14b46231e079a0fd9f3ca13d5d48113be76fd0f
ToppCell	facs-GAT-Fat-18m-Myeloid-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0930 ITGAX MCTP1 CTSS HCLS1	1.15e-04	169	125	5	7a7416fcbffcf57d19b477d9da091e04e3499524
ToppCell	droplet-Thymus-nan-18m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFCAB6 FERMT1 ITGAX FAM3D IQCA1	1.15e-04	169	125	5	4ac21e8199de4b6917eacadc56fffc6d886ee643
ToppCell	facs-GAT-Fat-18m-Myeloid\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0930 ITGAX MCTP1 CTSS HCLS1	1.15e-04	169	125	5	0e1a99cd77edcf32bcb513abd247b2b27409ac63
ToppCell	facs-GAT-Fat-18m-Myeloid-myeloid_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0930 ITGAX MCTP1 CTSS HCLS1	1.15e-04	169	125	5	9bbad31ef03078f5aa456f2e1b17b49c91545ff0
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO RYR2 DNAH1 GSTM1 HYDIN	1.15e-04	169	125	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	facs-Heart-LV-18m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAX LRP8 IQCA1 CTSS HCLS1	1.18e-04	170	125	5	4eaa22040e475100061475123aefa32b56481464
ToppCell	facs-Heart-LV-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAX LRP8 IQCA1 CTSS HCLS1	1.18e-04	170	125	5	60041b2e57e958f300a5bc76851705c8baf297c2
ToppCell	facs-Heart-LV-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAX LRP8 IQCA1 CTSS HCLS1	1.18e-04	170	125	5	793dde64f5517538b66de5f461a445c4ad6dd7b3
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO CLCN1 STXBP1 FRMPD3 CNR1	1.21e-04	171	125	5	99176a932569fa1c7e1c01009684f5a65244b96e
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANXA2 ANXA2P2 ACR NEDD4 TENM1	1.28e-04	173	125	5	61907116a1460bc157ba73b5edd108db7dd5de4b
ToppCell	facs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIAA0930 ITGAX RP2 CTSS HCLS1	1.32e-04	174	125	5	c52aed2ffe9c648e5f23e3459e2d331d6ca214e3
Disease	Brugada syndrome (implicated_via_orthology)	GSTM1 GSTM2 GSTM4	6.85e-07	5	122	3	DOID:0050451 (implicated_via_orthology)
Disease	Malignant mesothelioma	HDAC4 ANXA2 WNT3 RYR2 GSTM1 WWC1	6.31e-06	109	122	6	C0345967
Disease	Cognitive impairment	RYR2 DMXL1 SMYD3	1.11e-05	11	122	3	HP_0100543
Disease	level of glutathione S-transferase mu 1 in blood serum	GSTM1 GSTM2	1.70e-05	2	122	2	OBA_2041806
Disease	esophageal atresia (is_implicated_in)	EFTUD2 GSTM1	1.70e-05	2	122	2	DOID:10485 (is_implicated_in)
Disease	PR interval	ARID4A OBSCN BCL6 CDPF1 RYR2 FREM2 FAT1 DLEC1 SMYD3 CNR1	4.16e-05	495	122	10	EFO_0004462
Disease	Cryptophthalmos syndrome	GRIP1 FREM2	5.07e-05	3	122	2	C0265233
Disease	FRASER SYNDROME 1	GRIP1 FREM2	5.07e-05	3	122	2	C4551480
Disease	alcohol consumption measurement	EHBP1 EEF1AKMT4-ECE2 ARID4A TOPAZ1 WNT3 CYP21A2 PCLO PPM1G GRIP1 PTPRK EIF2B1 EIF5B RCOR3 PARD3 AFF4 WWC1	5.46e-05	1242	122	16	EFO_0007878
Disease	Fraser syndrome (implicated_via_orthology)	GRIP1 FREM2	1.01e-04	4	122	2	DOID:0090001 (implicated_via_orthology)
Disease	4-methyl-2-oxopentanoate measurement	GNPDA2 SMYD3	1.68e-04	5	122	2	EFO_0021022
Disease	Obesity	PPARGC1B GNPDA2 HADH CTSS CNR1 AFF4	2.16e-04	205	122	6	C0028754
Disease	Schizophrenia	HDAC4 RANBP9 GC FAM3D LRP8 GSTM1 GSTM2 STXBP1 PI4KA NAV1 CNP CNR1	3.06e-04	883	122	12	C0036341
Disease	schizophrenia (is_implicated_in)	LRP8 GSTM1 CNP CNR1	3.13e-04	78	122	4	DOID:5419 (is_implicated_in)
Disease	body surface area	PDXDC1 EEF1AKMT4-ECE2 CYP21A2 NSD1 BCL6 CDPF1 NFIL3 DLEC1 POLD3 PARD3	3.49e-04	643	122	10	EFO_0022196
Disease	cathepsin S measurement	MIA3 CTSS	4.67e-04	8	122	2	EFO_0008073
Disease	microcephaly (is_implicated_in)	NSD1 EFTUD2	4.67e-04	8	122	2	DOID:10907 (is_implicated_in)
Disease	nevus count, cutaneous melanoma	KIAA0930 MIA3 HDAC4 PPARGC1B	5.63e-04	91	122	4	EFO_0000389, EFO_0004632
Disease	Degenerative Diseases, Central Nervous System	GSTM1 GSTM2 GSTM4	5.65e-04	39	122	3	C0270715
Disease	Neurodegenerative Disorders	GSTM1 GSTM2 GSTM4	5.65e-04	39	122	3	C0524851
Disease	Degenerative Diseases, Spinal Cord	GSTM1 GSTM2 GSTM4	5.65e-04	39	122	3	C0751733
Disease	JT interval	MIA3 KIAA0232 OBSCN CDPF1 EEF1A2 CTSS	5.95e-04	248	122	6	EFO_0007885
Disease	Congenital small ears	EFTUD2 GRIP1 FREM2	6.55e-04	41	122	3	C0152423
Disease	osteonecrosis (is_implicated_in)	ANXA2 GSTM1	7.47e-04	10	122	2	DOID:10159 (is_implicated_in)
Disease	apolipoprotein A 1 measurement	PDXDC1 STAG1 CYP21A2 NSD1 GSTM1 GSTM2 PPARGC1B DLEC1 MAP2K6 CTSS SNTB1	8.04e-04	848	122	11	EFO_0004614
Disease	phenylacetylglutamine measurement	RBBP8 SNTB1	1.09e-03	12	122	2	EFO_0021013
Disease	diffuse large B-cell lymphoma (is_implicated_in)	BCL6 GSTM1	1.09e-03	12	122	2	DOID:0050745 (is_implicated_in)
Disease	myotonia congenita (implicated_via_orthology)	MYH6 CLCN1	1.09e-03	12	122	2	DOID:2106 (implicated_via_orthology)
Disease	estradiol measurement	RBBP8 PPARGC1B CPQ NAV1	1.15e-03	110	122	4	EFO_0004697
Disease	salicylurate measurement	SLAIN2 RYR2	1.28e-03	13	122	2	EFO_0010532
Disease	pimelic acid measurement, 3-methyladipic acid measurement	KIAA0232 SNTB1	1.49e-03	14	122	2	EFO_0010449, EFO_0010524
Disease	renal cell carcinoma (biomarker_via_orthology)	ANXA2 ANXA2P2	1.49e-03	14	122	2	DOID:4450 (biomarker_via_orthology)
Disease	serum IgG glycosylation measurement	EFCAB6 TOPAZ1 NEUROD4 KIAA0232 RYR2 MCTP1 DHX34 SNTB1	1.52e-03	523	122	8	EFO_0005193
Disease	QRS duration	PDXDC1 USP34 UBR4 CDPF1 PPARGC1B DLEC1	1.53e-03	298	122	6	EFO_0005055
Disease	neuroimaging measurement	PDXDC1 STAG1 MAP2 C5orf63 WNT3 CYP21A2 LRP8 EFTUD2 RAB3GAP2 PARD3 SLC4A9 WWC1	1.61e-03	1069	122	12	EFO_0004346
Disease	free cholesterol to total lipids in large HDL percentage	PDXDC1 GSTM1 GSTM2	1.63e-03	56	122	3	EFO_0022279
Disease	Hypertrophic Cardiomyopathy	MYH6 OBSCN RYR2	1.71e-03	57	122	3	C0007194
Disease	diffuse idiopathic skeletal hyperostosis	NFIL3 POLD3	1.72e-03	15	122	2	EFO_0007236
Disease	fibrinogen measurement, factor VII measurement	STAG1 CYP21A2 PARD3	1.80e-03	58	122	3	EFO_0004619, EFO_0004623
Disease	celiac disease	WNT3 PTPRK NAV1 HYDIN	1.89e-03	126	122	4	EFO_0001060
Disease	Disorder of eye	MAK GRIP1 FREM2 RP2 CNGA1	1.92e-03	212	122	5	C0015397
Disease	Sarcomatoid Renal Cell Carcinoma	PDXDC1 ANXA4 GSTM1 CPQ	2.00e-03	128	122	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	PDXDC1 ANXA4 GSTM1 CPQ	2.00e-03	128	122	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	PDXDC1 ANXA4 GSTM1 CPQ	2.00e-03	128	122	4	C1266044
Disease	Papillary Renal Cell Carcinoma	PDXDC1 ANXA4 GSTM1 CPQ	2.00e-03	128	122	4	C1306837
Disease	Renal Cell Carcinoma	PDXDC1 ANXA4 GSTM1 CPQ	2.00e-03	128	122	4	C0007134
Disease	obesity (implicated_via_orthology)	DHX33 GSTM1 GSTM2 GSTM4 CNR1	2.04e-03	215	122	5	DOID:9970 (implicated_via_orthology)
Disease	ulcerative colitis (is_implicated_in)	GC GSTM1	2.21e-03	17	122	2	DOID:8577 (is_implicated_in)
Disease	nevus count	HDAC4 PPARGC1B	2.48e-03	18	122	2	EFO_0004632
Disease	obsessive-compulsive disorder, autism spectrum disorder	ANXA2 DLEC1	2.77e-03	19	122	2	EFO_0003756, EFO_0004242
Disease	hydrocephalus (implicated_via_orthology)	DPCD HYDIN	2.77e-03	19	122	2	DOID:10908 (implicated_via_orthology)
Disease	bipolar disorder	SLAIN2 MAP2 PCLO EEF1A2 MCTP1 DLEC1 SMYD3 PUS7	2.80e-03	577	122	8	MONDO_0004985
Disease	creatinine measurement	STAG1 CYP21A2 OBSCN NSD1 PPM1G EEF1A2 HOXA13 RCOR3 DLEC1 PARD3 CTSS	2.84e-03	995	122	11	EFO_0004518
Disease	freckles	PPARGC1B PARD3	3.07e-03	20	122	2	EFO_0003963
Disease	Lymphoma, Follicular	BCL6 RRAGC	3.07e-03	20	122	2	C0024301
Disease	emphysema imaging measurement	PTPRK DLEC1 ANKRD12 WWC1	3.22e-03	146	122	4	EFO_0007626
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	PDXDC1 ANXA4 GSTM1 CPQ	3.38e-03	148	122	4	C0279702
Disease	saturated fatty acids to total fatty acids percentage	GSTM1 GSTM2	3.38e-03	21	122	2	EFO_0022305
Disease	cerebellar cortex volume measurement	CYP21A2 WWC1	3.38e-03	21	122	2	EFO_0010291
Disease	Major Depressive Disorder	MAP2 PCLO LRP8 CNP CNR1	3.45e-03	243	122	5	C1269683
Disease	multiple sclerosis (is_implicated_in)	GC GSTM1 CNP	3.47e-03	73	122	3	DOID:2377 (is_implicated_in)
Disease	Retinitis pigmentosa	MAK RP2 CNGA1	3.61e-03	74	122	3	cv:C0035334
Disease	cortical surface area measurement	USP34 STAG1 MAP2 WNT3 CYP21A2 LRP8 GRIP1 RAB3GAP2 NAV1 POLD3 PARD3 SNTB1 WWC1	3.80e-03	1345	122	13	EFO_0010736
Disease	Paroxysmal atrial fibrillation	USP34 MYH6 WNT3 IRF2BPL	4.07e-03	156	122	4	C0235480
Disease	familial atrial fibrillation	USP34 MYH6 WNT3 IRF2BPL	4.07e-03	156	122	4	C3468561
Disease	Persistent atrial fibrillation	USP34 MYH6 WNT3 IRF2BPL	4.07e-03	156	122	4	C2585653

Protein segments in the cluster

Peptide	Gene	Start	Entry
DYDMGLDAPKTISSD	C5orf63	101	A6NC05
ESFKELDPDSSMGKA	BARGIN	91	Q6ZT62
GSDSEDSELMYQPKA	SLC4A9	961	Q96Q91
LKMGAKTYPDTDSFN	CPQ	256	Q9Y646
MKAADEPAYLTVGTD	ARID4A	1	P29374
SIDPGADLSQYKMDV	RBBP8	656	Q99708
GGPLMCKDSKESAYV	ACR	241	P10323
MADADGATKFPDVEK	ALG5	161	Q9Y673
ASKGKTMADSSYQPE	FERMT1	471	Q9BQL6
EESYVMKDPFTSDKD	CDPF1	41	Q6NVV7
PAQYDASELKASMKG	ANXA2	106	P07355
AEKLYKSMKGLGTDD	ANXA4	251	P09525
DSDSNMVEKPYGRKS	ANKRD12	16	Q6UB98
PAQYDASELKASMKG	ANXA2P2	106	A6NMY6
KKTAFDPSVDMEDSG	DMXL1	1296	Q9Y485
LVDKDFMTPKTADYA	DISP1	431	Q96F81
ILADSGIDTSDMKYP	IQCA1	141	Q86XH1
EAYAKPEAEAMPTSE	ARMCX4	1061	Q5H9R4
MKLKNYLAPDATAAD	AFF4	981	Q9UHB7
KMLKDAFSLLAYSDP	RANBP9	646	Q96S59
MDGNDSDYDPKKEAK	RCOR3	166	Q9P2K3
AKEYGLPFMETSAKT	RAB26	196	Q9ULW5
RVFPYMEGDVSSKDK	NSD1	1811	Q96L73
AGSSHLDYPKDSDLM	RAD1	196	O60671
SLDYKDVIPMADAAG	ITGAX	266	P20702
FSAATYLMDKVGKSP	RAB3GAP2	1066	Q9H2M9
AEYDLMVKATDKGSP	FAT1	1631	Q14517
SYDDPGTKMNDESRK	FAM3D	146	Q96BQ1
GMYDAKDDFPLRKTA	HDAC4	231	P56524
DLKAMDSNGLSDPYV	MCTP1	481	Q6DN14
KKEAEEEYRNSMPAS	LUC7L	166	Q9NQ29
KMTYLPKTSGSEDDN	NEDD4	566	P46934
SPDMDGYPALKVDKE	WWC1	876	Q8IX03
KEDIDTAMKLGAGYP	HADH	241	Q16836
LMYDDTSKAKESAEP	FREM2	2381	Q5SZK8
KHPMDSKGEESKISY	KIAA0930	146	Q6ICG6
TFGDKIKDDNLMPAY	CYP21A2	176	P08686
DPGYSTEMKEESVKK	ENOSF1	411	Q7L5Y1
EDPKLLSMAYSAVGK	ECPAS	411	Q5VYK3
YVTESQPDLSGKKMA	EIF2B1	151	Q14232
DAVSKPGMDYELKLF	IRF2BPL	406	Q9H1B7
KYGDSMTEADKTKPL	PCLO	3496	Q9Y6V0
KDPGSTEGKDLYMEN	KIAA0232	376	Q92628
ESDLTFKIGPEYKSM	PDXDC1	556	Q6P996
VEMKDSGYKVSDPEN	NFIL3	416	Q16649
SSYEEKKYTMGDAPD	GSTM2	26	P28161
YFMSKGILDDSPKEI	FBXO8	156	Q9NRD0
DIDYKSGTPMQSAAK	PI4KA	1786	P42356
DMTPFLKESGNALDY	KIAA2012	711	Q0VF49
GAMLAYTPLDEKSLA	MORF4L2	236	Q15014
SELMKEVPGDDYKNK	LRRC37B	891	Q96QE4
MPDGQFKDISLSDYK	PRDX1	21	Q06830
DLSTKDLGDPSMDKA	OBSCN	4861	Q5VST9
TDPAADLYKFAEEMK	DNAH1	3681	Q9P2D7
AKEKADAIYDMIGFP	EEF1AKMT4-ECE2	606	P0DPD8
YSDSQSDFMPSLKGK	CEFIP	711	Q711Q0
RNPSGDDTKMYKLDV	IGSF10	2216	Q6WRI0
SRDKYKSSLFPGNME	HYDIN	2836	Q4G0P3
PSLKGLMEAISDKYD	GRHL1	551	Q9NZI5
MFTSELSEKGKPYVD	KLHL12	61	Q53G59
MKEAGAETPSFYSAL	EFCAB6	1411	Q5THR3
YSLSEMEAAGKKPAG	DNAJB2	261	P25686
DASDGKDELSYSIPM	FRMPD3	1541	Q5JV73
GVNKMDSTEPAYSEK	EEF1A2	151	Q05639
PDGKEMAEEYDEKTS	DPCD	31	Q9BVM2
DTGMVKAKKYNPDSG	DHX33	371	Q9H6R0
DGTKMVSADAYKITP	CNP	76	P09543
EDIKGDMASKLGYFP	CNR1	31	P21554
SDMHYSVAEGLKPAA	BCL6	271	P41182
PSYGEMAAEKLKERS	EHBP1	886	Q8NDI1
EDYDFGASHSKKPSM	MAK	411	P20794
AKYFDGDLSKVPTMA	GNPDA2	171	Q8TDQ7
LETNDGSSEKPYFMD	SLC44A3	601	Q8N4M1
KGIDSDASYPYKAMD	CTSS	196	P25774
STRGDADMYDLPKKE	EMD	66	P50402
DSSPAQKPGKLSDMY	GRIP1	781	Q9Y3R0
GETFSMDSIKCYPDK	DLEC1	661	Q9Y238
VDSGKVKEMSYDPQA	DHX34	456	Q14147
PKADMVTYDDKAEAG	ERVFC1	211	P60507
KFYNKSEDGDTPDMK	RYR2	4791	Q92736
SAYMDKASDPKEQEV	LRP8	476	Q14114
SYMIVDSSDHDPGEK	PTPRK	76	Q15262
KSYDKPAVDDDDEGM	PARD3	931	Q8TEW0
ATDSLPGKFEDMYKL	MKNK1	36	Q9BUB5
DSVAKTIDAGCKPYM	MAP2K6	206	P52564
DMLASLGKNPTDAYL	MYL12B	56	O14950
FKDYISKMDPASTLG	NAV1	1466	Q8NEY1
KKFKYAEDMGPGAAE	P2RX1	366	P51575
PSEDRKIGENYSKMD	SYDE2	1116	Q5VT97
SPYEKLKMSSDDGIR	SNTB1	481	Q13884
EGKAYVDDTPAEQMK	EPRS1	286	P07814
LKEDGSGSAYDKESM	RRAGC	301	Q9HB90
SLPAPKTYGSMKDDS	SLAIN2	561	Q9P270
YSKDANDVITMDPKD	TRGC2	121	P03986
GEDMKTPAKSGVEKY	MIA3	336	Q5JRA6
GFNEMEAPTTAYKKT	HCLS1	211	P14317
MATYDSFLEKSPSDK	NHS	756	Q6T4R5
TAKPKVEMYSGSDDD	EIF5B	126	O60841
SSYEEKKYTMGDAPD	GSTM4	26	Q03013
SSYEEKKYTMGDAPD	GSTM1	26	P09488
AGKALDMSYDHKPED	PPM1G	356	O15355
DPMLDFYSDKNAKLT	TENT5D	181	Q8NEK8
EALPASGKSKYEAMD	PPARGC1B	996	Q86YN6
SEGKYRALKMDFSLP	PUS7	616	Q96PZ0
KVKADRDESSPYAAM	RPS14	61	P62263
VPYDMSGDRELKSSK	TELO2	496	Q9Y4R8
GGYAKDAKMKAPSSL	TENM1	1486	Q9UKZ4
AMLKDSGPLFNTDYD	POLD3	106	Q15054
PDGTEDADKSAYLMG	MYH6	376	P13533
QDKLDAYKADDPTMG	STXBP1	206	P61764
AYKADDPTMGEGPDK	STXBP1	211	P61764
FADKYMDTAGPAAEE	HOXA13	206	P31271
KLMDGAPSESEKLYS	SMYD3	111	Q9H7B4
KPYMETAKTGDNRKE	ACTL7A	101	Q9Y615
LTEYPDAKTMLEEKG	CNGA1	581	P29973
EMARKLSELPYDGKA	CLCN1	676	P35523
ISFYEKMQSDKGSIP	TRBV13	76	A0A0A6YYD4
EEKKGAETQMPSYSL	TEP1	196	Q99973
DPKDYMFSGLKDETV	RP2	36	O75695
DPGNTKVMDKYTFEL	GC	336	P02774
GDFLKDKYDSASEMV	WNT3	231	P56703
PMLLSKYSADAEKVA	STAG1	576	Q8WVM7
LAKDFYKNGTVMAPD	MAP2	791	P11137
ASEPLGYESMASKED	TOPAZ1	431	Q8N9V7
AKYEIMDGAPVKGES	VPS26A	231	O75436
PTMVETSKGKDDVYD	USP34	3121	Q70CQ2
PDTKGKSYLFNIMDT	EFTUD2	191	Q15029
DMPIYEAADKALKTF	UBR4	5131	Q5T4S7
KQDGSPDLEKSYSFM	NEUROD4	266	Q9HD90