Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

MYO1G APPBP2 HDAC6 DCDC1 KIF1A MYO5B MYO9A MYO9B OBSCN CCDC187 SLC4A1 MAPK8IP3 IQGAP1 SPTBN4 NEFH PTPN4 LRPPRC MYO3A SHROOM1 CCT5 MACF1 SSH2 PLEC TRIM36 SCIN ALDOC AGTPBP1 KLHL17

2.78e-08109915628GO:0008092
GeneOntologyMolecularFunctionactin filament binding

MYO1G MYO5B MYO9A MYO9B IQGAP1 SPTBN4 LRPPRC MYO3A SHROOM1 MACF1 PLEC SCIN KLHL17

2.79e-0822715613GO:0051015
GeneOntologyMolecularFunctionactin binding

MYO1G HDAC6 MYO5B MYO9A MYO9B SLC4A1 IQGAP1 SPTBN4 LRPPRC MYO3A SHROOM1 MACF1 SSH2 PLEC SCIN KLHL17

1.14e-0647915616GO:0003779
GeneOntologyMolecularFunctionmicrofilament motor activity

MYO1G MYO5B MYO9A MYO9B MYO3A

1.11e-05381565GO:0000146
GeneOntologyMolecularFunctionankyrin binding

OBSCN SLC4A1 SPTBN4 PLEC

2.83e-05231564GO:0030506
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO1G APPBP2 KIF1A MYO5B MYO9A MYO9B MYO3A

3.96e-051181567GO:0003774
GeneOntologyMolecularFunctiondopamine neurotransmitter receptor activity, coupled via Gs

DRD1 DRD5

6.06e-0521562GO:0001588
GeneOntologyMolecularFunctioncalmodulin binding

MYO1G MYO5B MYO9B IQCF1 OBSCN IQGAP1 ITPKA MYO3A IQCF3

8.40e-052301569GO:0005516
GeneOntologyMolecularFunctionATP-dependent activity

MYO1G APPBP2 KIF1A MYO5B MYO9A MYO9B NAIP MYO3A CCT5 RECQL4 SMARCA2 MACF1 CHD6 DNA2

3.36e-0461415614GO:0140657
GeneOntologyMolecularFunctiontubulin binding

APPBP2 HDAC6 DCDC1 KIF1A CCDC187 NEFH LRPPRC CCT5 MACF1 TRIM36 AGTPBP1

5.57e-0442815611GO:0015631
GeneOntologyMolecularFunctionphosphatidylinositol-3,4,5-trisphosphate binding

MYO1G GBF1 OBSCN IQGAP1

5.78e-04491564GO:0005547
GeneOntologyMolecularFunctiondopamine neurotransmitter receptor activity

DRD1 DRD5

5.97e-0451562GO:0004952
GeneOntologyMolecularFunctionsmall GTPase binding

DMXL2 MYO5B MYO9B PLEKHG2 CHM IQGAP1 ITPKA TBC1D20 EXOC5

9.70e-043211569GO:0031267
GeneOntologyBiologicalProcesscell morphogenesis

PLOD3 HDAC6 KIF1A MYO5B MYO9A MYO9B NTF3 NFASC SIPA1 AP3B1 BRWD3 MAPK8IP3 IQGAP1 ITPKA TBC1D20 SPTBN4 NEFH MYO3A SHROOM1 CDH20 SPINT2 CELSR2 PTPRM NKX2-1 ANAPC2 MACF1 EIF2AK4 PLEC PHIP EPHA4

5.36e-09119415630GO:0000902
GeneOntologyBiologicalProcessorganelle transport along microtubule

HDAC6 KIF1A AP3B1 MREG NEFH LRPPRC AP3B2 AGTPBP1

7.31e-07971568GO:0072384
GeneOntologyBiologicalProcessneuron development

DRD1 HDAC6 KIF1A MYO5B UBE4B NRTN MYO9A NTF3 BAG5 HLA-F NFASC GRID2 MAPK8IP3 IQGAP1 ITPKA SPTBN4 NEFH RNF220 MYO3A CELSR2 HOXD9 PTPRM NKX2-1 ANAPC2 MACF1 EIF2AK4 AGTPBP1 EPHA4

4.63e-06146315628GO:0048666
GeneOntologyBiologicalProcesscytoskeleton-dependent intracellular transport

HDAC6 KIF1A MYO5B AP3B1 MAPK8IP3 MREG NEFH LRPPRC AP3B2 AGTPBP1

8.55e-0622515610GO:0030705
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

HDAC6 KIF1A MYO5B MYO9A MYO9B NTF3 NFASC MAPK8IP3 IQGAP1 ITPKA SPTBN4 NEFH CELSR2 PTPRM NKX2-1 ANAPC2 MACF1 EIF2AK4 EPHA4

1.42e-0581915619GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

HDAC6 KIF1A MYO5B MYO9A MYO9B NTF3 NFASC MAPK8IP3 IQGAP1 ITPKA SPTBN4 NEFH CELSR2 PTPRM NKX2-1 ANAPC2 MACF1 EIF2AK4 EPHA4

1.60e-0582615619GO:0048858
GeneOntologyBiologicalProcesstransport along microtubule

HDAC6 KIF1A AP3B1 MAPK8IP3 MREG NEFH LRPPRC AP3B2 AGTPBP1

1.96e-051971569GO:0010970
GeneOntologyBiologicalProcessaxonal transport

HDAC6 KIF1A AP3B1 MAPK8IP3 AP3B2 AGTPBP1

2.23e-05751566GO:0098930
GeneOntologyBiologicalProcesstransmission of nerve impulse

DRD1 DRD5 NFASC SPTBN4 P2RX2 SCN9A PLEC

2.31e-051121567GO:0019226
GeneOntologyBiologicalProcessneuron projection development

HDAC6 KIF1A MYO5B UBE4B NRTN MYO9A NTF3 BAG5 HLA-F NFASC GRID2 MAPK8IP3 IQGAP1 ITPKA SPTBN4 NEFH MYO3A CELSR2 PTPRM NKX2-1 ANAPC2 MACF1 EIF2AK4 EPHA4

3.62e-05128515624GO:0031175
GeneOntologyBiologicalProcessneuron projection morphogenesis

HDAC6 KIF1A MYO5B MYO9A NTF3 NFASC MAPK8IP3 IQGAP1 ITPKA SPTBN4 NEFH CELSR2 PTPRM NKX2-1 ANAPC2 MACF1 EIF2AK4 EPHA4

3.75e-0580215618GO:0048812
GeneOntologyBiologicalProcessanterograde axonal transport

KIF1A AP3B1 MAPK8IP3 AP3B2 AGTPBP1

5.95e-05551565GO:0008089
GeneOntologyBiologicalProcessaxo-dendritic transport

HDAC6 KIF1A AP3B1 MAPK8IP3 AP3B2 AGTPBP1

1.01e-04981566GO:0008088
GeneOntologyBiologicalProcessmicrotubule-based transport

HDAC6 KIF1A AP3B1 MAPK8IP3 MREG NEFH LRPPRC AP3B2 AGTPBP1

1.36e-042531569GO:0099111
GeneOntologyBiologicalProcesspositive regulation of dendrite morphogenesis

HDAC6 MYO5B ITPKA ANAPC2 EPHA4

1.54e-04671565GO:0050775
GeneOntologyBiologicalProcessleukocyte migration involved in immune response

PLEC FUT7

1.70e-0431562GO:0002522
GeneOntologyBiologicalProcesspositive regulation of cell morphogenesis

HDAC6 MYO5B ITPKA ANAPC2 EPHA4

1.77e-04691565GO:0010770
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

HDAC6 KIF1A MYO5B NTF3 NFASC MAPK8IP3 ITPKA SPTBN4 NEFH MYO3A CELSR2 PTPRM NKX2-1 ANAPC2 MACF1 EPHA4

1.80e-0474815616GO:0048667
GeneOntologyBiologicalProcessfertilization

SPAM1 IQCF1 AP3B1 FETUB ZFX SPTBN4 HOXD9 CCT5 TRIM36

1.82e-042631569GO:0009566
GeneOntologyBiologicalProcessestablishment of organelle localization

GBF1 HDAC6 KIF1A MYO5B RPS15 AP3B1 SNAP29 MREG NEFH LRPPRC EXOC5 AP3B2 AGTPBP1

2.69e-0454615613GO:0051656
GeneOntologyBiologicalProcessestablishment of vesicle localization

GBF1 KIF1A MYO5B AP3B1 SNAP29 MREG EXOC5 AP3B2

3.13e-042241568GO:0051650
GeneOntologyBiologicalProcessactomyosin contractile ring assembly actin filament organization

IQGAP1 PLEC

3.38e-0441562GO:2000689
GeneOntologyCellularComponentaxon

DRD1 DRD5 HDAC6 KIF1A NRTN MYO9A NTF3 NFASC GRIA3 AP3B1 MAPK8IP3 IQGAP1 SPTBN4 NEFH P2RX2 ELFN1 AP3B2 SCN9A PLEC ALDOC AGTPBP1 EPHA4

1.01e-0689115822GO:0030424
GeneOntologyCellularComponentaxon cytoplasm

HDAC6 KIF1A AP3B1 MAPK8IP3 AP3B2 AGTPBP1

1.26e-05681586GO:1904115
GeneOntologyCellularComponentneuron projection cytoplasm

HDAC6 KIF1A AP3B1 MAPK8IP3 AP3B2 AGTPBP1 KLHL17

2.05e-051101587GO:0120111
GeneOntologyCellularComponentpostsynaptic cytoskeleton

MYO5B MYO9B ITPKA NEFH

4.13e-05261584GO:0099571
GeneOntologyCellularComponentmyosin complex

MYO1G MYO5B MYO9A MYO9B MYO3A

8.34e-05591585GO:0016459
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

APPBP2 EPPK1 HDAC6 DCDC1 KIF1A MYO9A KRT32 MYO9B IQGAP1 SPTBN4 NEFH LRPPRC MYO3A SHROOM1 CCT5 MACF1 PLEC CSPP1

1.59e-0489915818GO:0099513
GeneOntologyCellularComponentdendrite

DRD1 DRD5 HDAC6 KIF1A MYO5B NTF3 NFASC GRIA3 GRID2 MAPK8IP3 ITPKA NEFH P2RX2 ELFN1 PLEC EPHA4 KLHL17

2.76e-0485815817GO:0030425
GeneOntologyCellularComponentdendritic tree

DRD1 DRD5 HDAC6 KIF1A MYO5B NTF3 NFASC GRIA3 GRID2 MAPK8IP3 ITPKA NEFH P2RX2 ELFN1 PLEC EPHA4 KLHL17

2.84e-0486015817GO:0097447
GeneOntologyCellularComponentpostsynaptic actin cytoskeleton

MYO5B MYO9B ITPKA

3.76e-04191583GO:0098871
GeneOntologyCellularComponentactin cytoskeleton

MYO1G MYO5B MYO9A MYO9B IQGAP1 ITPKA SPTBN4 MYO3A SHROOM1 MACF1 NEURL1B SCIN KLHL17

4.46e-0457615813GO:0015629
GeneOntologyCellularComponentdendritic spine

DRD1 DRD5 MYO5B GRIA3 GRID2 ITPKA P2RX2 EPHA4

5.21e-042421588GO:0043197
GeneOntologyCellularComponentcell cortex

MYO5B MYO9B SLC4A1 IQGAP1 SPTBN4 EXOC5 SHROOM1 MACF1 EXOC3L1 SCIN

5.37e-0437115810GO:0005938
GeneOntologyCellularComponentsupramolecular fiber

APPBP2 EPPK1 HDAC6 DCDC1 KIF1A MYO9A KRT32 MYO9B OBSCN SLC4A1 IQGAP1 SPTBN4 NEFH LRPPRC MYO3A SHROOM1 CCT5 MACF1 PLEC CSPP1

5.93e-04117915820GO:0099512
GeneOntologyCellularComponentneuron spine

DRD1 DRD5 MYO5B GRIA3 GRID2 ITPKA P2RX2 EPHA4

5.96e-042471588GO:0044309
GeneOntologyCellularComponentinclusion body

HDAC6 BAG5 NEFH HOXC9 ARIH1

6.07e-04901585GO:0016234
GeneOntologyCellularComponentsupramolecular polymer

APPBP2 EPPK1 HDAC6 DCDC1 KIF1A MYO9A KRT32 MYO9B OBSCN SLC4A1 IQGAP1 SPTBN4 NEFH LRPPRC MYO3A SHROOM1 CCT5 MACF1 PLEC CSPP1

6.46e-04118715820GO:0099081
GeneOntologyCellularComponentbrush border

DRD5 MYO5B SLC9A2 TREH PLEC SCIN

1.06e-031521586GO:0005903
GeneOntologyCellularComponentcluster of actin-based cell projections

DRD5 MYO5B MYO3A SLC9A2 TREH PLEC SCIN

1.57e-032231587GO:0098862
GeneOntologyCellularComponentpostsynapse

DRD1 DRD5 KIF1A MYO5B MYO9A MYO9B GRIA3 GRID2 ITPKA NEFH RNF220 P2RX2 ELFN1 MACF1 ALDOC EPHA4 KLHL17

1.83e-03101815817GO:0098794
DomainIQ

MYO5B MYO9A MYO9B IQCF1 OBSCN IQGAP1 MYO3A IQCF3 SCN9A

8.40e-09711589PF00612
DomainIQ

MYO5B MYO9A MYO9B IQCF1 OBSCN IQGAP1 MYO3A IQCF3 SCN9A

2.74e-08811589SM00015
DomainIQ_motif_EF-hand-BS

MYO5B MYO9A MYO9B IQCF1 OBSCN IQGAP1 MYO3A IQCF3 SCN9A

6.95e-08901589IPR000048
DomainIQ

MYO5B MYO9A MYO9B IQCF1 OBSCN IQGAP1 MYO3A IQCF3 SCN9A

9.26e-08931589PS50096
DomainAP_beta

AP3B1 AP3B2 AP4B1

5.87e-0651583IPR026739
Domain-

EPPK1 MACF1 PLEC

1.17e-05615833.90.1290.10
DomainMyosin_head_motor_dom

MYO1G MYO5B MYO9A MYO9B MYO3A

1.63e-05381585IPR001609
DomainMYOSIN_MOTOR

MYO1G MYO5B MYO9A MYO9B MYO3A

1.63e-05381585PS51456
DomainMyosin_head

MYO1G MYO5B MYO9A MYO9B MYO3A

1.63e-05381585PF00063
DomainMYSc

MYO1G MYO5B MYO9A MYO9B MYO3A

1.63e-05381585SM00242
DomainPlectin

EPPK1 MACF1 PLEC

2.03e-0571583PF00681
DomainPlectin_repeat

EPPK1 MACF1 PLEC

2.03e-0571583IPR001101
DomainPLEC

EPPK1 MACF1 PLEC

2.03e-0571583SM00250
DomainAP3_beta

AP3B1 AP3B2

7.11e-0521582IPR026740
DomainAP3B_C

AP3B1 AP3B2

7.11e-0521582IPR029390
DomainAP3B1_C

AP3B1 AP3B2

7.11e-0521582PF14796
DomainAP3B1_C

AP3B1 AP3B2

7.11e-0521582SM01355
DomainHomeobox_metazoa

EVX2 HOXA6 HOXC5 HOXC9 HOXD9 NKX2-1

1.16e-04901586IPR020479
DomainCH

LRCH3 IQGAP1 SPTBN4 MACF1 PLEC

2.23e-04651585SM00033
DomainClathrin/coatomer_adapt-like_N

AP3B1 AP3B2 AP4B1

2.51e-04151583IPR002553
DomainAdaptin_N

AP3B1 AP3B2 AP4B1

2.51e-04151583PF01602
DomainCH

LRCH3 IQGAP1 SPTBN4 MACF1 PLEC

3.16e-04701585PF00307
Domain-

LRCH3 IQGAP1 SPTBN4 MACF1 PLEC

3.38e-047115851.10.418.10
DomainCH

LRCH3 IQGAP1 SPTBN4 MACF1 PLEC

3.84e-04731585PS50021
DomainB2-adapt-app_C

AP3B1 AP4B1

4.22e-0441582SM01020
DomainHox9_activation_N

HOXC9 HOXD9

4.22e-0441582IPR006711
DomainHXA9/HXB9/HXC9

HOXC9 HOXD9

4.22e-0441582IPR017112
DomainB-adaptin_app_sub_C

AP3B1 AP4B1

4.22e-0441582IPR015151
DomainHox9_act

HOXC9 HOXD9

4.22e-0441582PF04617
DomainCH-domain

LRCH3 IQGAP1 SPTBN4 MACF1 PLEC

4.36e-04751585IPR001715
DomainDopamine_rcpt

DRD1 DRD5

6.99e-0451582IPR000929
DomainACTININ_2

SPTBN4 MACF1 PLEC

9.29e-04231583PS00020
DomainACTININ_1

SPTBN4 MACF1 PLEC

9.29e-04231583PS00019
DomainActinin_actin-bd_CS

SPTBN4 MACF1 PLEC

9.29e-04231583IPR001589
DomainBRK

SMARCA2 CHD6

1.04e-0361582SM00592
DomainBRK_domain

SMARCA2 CHD6

1.04e-0361582IPR006576
DomainBRK

SMARCA2 CHD6

1.04e-0361582PF07533
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DMXL2 HDAC6 KIF1A UBE4B PPRC1 RBP4 RNF40 DCAF5 CCDC85A BRWD3 CREBZF MAPK8IP3 IQGAP1 SPTBN4 CRNKL1 RNF220 SURF6 MACF1 CHD6 PLEC ZBTB11 WDR13 VARS1 AGTPBP1

5.07e-0912851592435914814
Pubmed

Global control of motor neuron topography mediated by the repressive actions of a single hox gene.

HOXA6 HOXC5 HOXC9 CDH20 HOXD9 EPHA4

1.44e-0836159620826310
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DMXL2 MYO5B MYO9A RPS15 NFASC SIPA1 AP3B1 SLC4A1 MAPK8IP3 LRCH3 IQGAP1 ITPKA SPTBN4 NEFH LRPPRC CCT5 AP3B2 MACF1 SSH2 PLEC ALDOC VARS1 AGTPBP1

1.66e-0714311592337142655
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPPK1 GBF1 PLOD3 UBE4B MYO9B PPRC1 FBXL14 OBSCN RNF40 SFI1 COMTD1 MAPK8IP3 CELSR1 KMT2D CELSR2 FAM83F CSAD SURF6 PLEC KLHL17

1.79e-0711051592035748872
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SPAM1 HDAC6 DCDC1 SIPA1 PCMTD1 DCAF5 BRWD3 SLC4A1 HMG20B SNAP29 SURF6 NFKBIL1 SMARCA2 MACF1 DNA2 WDR13 PHIP AGTPBP1 PML

9.29e-0711161591931753913
Pubmed

Hox patterning of the vertebrate rib cage.

HOXA6 HOXC5 HOXC9 HOXD9

9.56e-0717159417626057
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RNF130 KIF1A UBE4B MYO9A NTF3 NAIP OBSCN NFASC BRWD3 MAPK8IP3 LRCH3 SNAP29 SPTBN4 PTPN4 LRPPRC SMARCA2 CSTF3 MACF1 CHD6 EIF2AK4 ARIH1 WDR13

1.28e-0614891592228611215
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

APPBP2 GBF1 HDAC6 KIF1A UBE4B MCL1 PCMTD1 RNF220 MACF1 PLEC AGTPBP1 PML

2.43e-064811591228190767
Pubmed

Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects.

HOXA6 HOXC5 HOXC9 HOXD9

4.16e-062415949367423
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

RNF130 KIF1A NAIP SOX13 ZFX HMG20B EVX2 HOXA6 HOXC5 HOXC9 NKX2-1 SMARCA2 MACF1 PHIP

5.23e-067091591422988430
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PLOD3 MYO5B FBXL14 BAG5 RPS15 AP3B1 PTPN4 KMT2D CCT5 PTPRM CSTF3 EIF2AK4 SSH2 TRIM36 SCIN CSPP1 AGTPBP1

6.91e-0610491591727880917
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

DMXL2 NBEAL1 AP3B1 SNAP29 AP3B2 AP4B1 TRIM36 SCIN WDR13

7.15e-06285159934369648
Pubmed

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays.

NFASC SPTBN4 TRIM36

7.72e-069159326671463
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

EPPK1 KIF1A RPS15 IQGAP1 CRNKL1 LRPPRC CCT5 SURF6 SMARCA2 MACF1 PLEC ZBTB11 PHIP

1.05e-056531591322586326
Pubmed

Ephrin-A5/EphA4 signalling controls specific afferent targeting to cochlear hair cells.

GRIA3 NEFH EPHA4

1.10e-0510159323385583
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

EPPK1 GBF1 OBSCN AP3B1 ESYT3 LRPPRC GLDC SMARCA2 ALDOC

1.20e-05304159932235678
Pubmed

Sf3b4 regulates chromatin remodeler splicing and Hox expression.

HOXA6 HOXC5 HOXC9 HOXD9

1.37e-0532159437167859
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

RNF130 EPPK1 SFI1 AP3B1 IQGAP1 EXOC5 CCT5 ANAPC2 SMARCA2 CSTF3 MACF1 PLEC

1.65e-055821591220467437
Pubmed

Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice.

CELSR1 CELSR2 EPHA4

2.00e-0512159320631168
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

EPPK1 TRA2B MYO5B MYO9B IQGAP1 CRNKL1 LRPPRC SPINT2 CCT5 CSTF3 MACF1 PLEC SCIN IMP3 VARS1 PHIP

2.04e-0510241591624711643
Pubmed

Distribution of postsynaptic GABA(A) receptor aggregates in the deep cerebellar nuclei of normal and mutant mice.

GRID2 AGTPBP1

2.08e-052159211984816
Pubmed

Plakins in development and disease.

EPPK1 PLEC

2.08e-052159217499243
Pubmed

PV plasticity sustained through D1/5 dopamine signaling required for long-term memory consolidation.

DRD1 DRD5

2.08e-052159226807952
Pubmed

Role of the extracellular amino terminus and first membrane-spanning helix of dopamine D1 and D5 receptors in shaping ligand selectivity and efficacy.

DRD1 DRD5

2.08e-052159219786093
Pubmed

Drosophila ATP6AP2/VhaPRR functions both as a novel planar cell polarity core protein and a regulator of endosomal trafficking.

CELSR1 CELSR2

2.08e-052159223292348
Pubmed

Functional importance of two conserved residues in intracellular loop 1 and transmembrane region 2 of Family A GPCRs: insights from ligand binding and signal transduction responses of D1 and D5 dopaminergic receptor mutants.

DRD1 DRD5

2.08e-052159226186971
Pubmed

Differential roles of the dopamine 1-class receptors, D1R and D5R, in hippocampal dependent memory.

DRD1 DRD5

2.08e-052159224843151
Pubmed

Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor.

DRD1 DRD5

2.08e-05215921831904
Pubmed

The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1.

IQGAP1 PTPRM

2.08e-052159216380380
Pubmed

Distinct roles of D1 and D5 dopamine receptors in motor activity and striatal synaptic plasticity.

DRD1 DRD5

2.08e-052159213679419
Pubmed

Role of D1-like receptors in amphetamine-induced behavioral sensitization: a study using D1A receptor knockout mice.

DRD1 DRD5

2.08e-052159211823893
Pubmed

Dopamine receptor ligands. Part 18: (1) modification of the structural skeleton of indolobenzazecine-type dopamine receptor antagonists.

DRD1 DRD5

2.08e-052159220180564
Pubmed

EMG analysis of harmaline-induced tremor in normal and three strains of mutant mice with Purkinje cell degeneration and the role of the inferior olive.

GRID2 AGTPBP1

2.08e-05215927666163
Pubmed

Differential dependence of the D1 and D5 dopamine receptors on the G protein gamma 7 subunit for activation of adenylylcyclase.

DRD1 DRD5

2.08e-052159211500503
Pubmed

The δ2 glutamate receptor gates long-term depression by coordinating interactions between two AMPA receptor phosphorylation sites.

GRID2 PTPN4

2.08e-052159223431139
Pubmed

The third intracellular loop of D1 and D5 dopaminergic receptors dictates their subtype-specific PKC-induced sensitization and desensitization in a receptor conformation-dependent manner.

DRD1 DRD5

2.08e-052159221893192
Pubmed

Activation of D1/5 Dopamine Receptors: A Common Mechanism for Enhancing Extinction of Fear and Reward-Seeking Behaviors.

DRD1 DRD5

2.08e-052159226763483
Pubmed

Differentiation of forebrain and hippocampal dopamine 1-class receptors, D1R and D5R, in spatial learning and memory.

DRD1 DRD5

2.08e-052159226174222
Pubmed

Class IX Myosins: Motorized RhoGAP Signaling Molecules.

MYO9A MYO9B

2.08e-052159232451867
Pubmed

LRPPRC sustains Yap-P27-mediated cell ploidy and P62-HDAC6-mediated autophagy maturation and suppresses genome instability and hepatocellular carcinomas.

HDAC6 LRPPRC

2.08e-052159232203162
Pubmed

The cooperative roles of the dopamine receptors, D1R and D5R, on the regulation of renal sodium transport.

DRD1 DRD5

2.08e-052159224552847
Pubmed

D1/D5 modulation of synaptic NMDA receptor currents.

DRD1 DRD5

2.08e-052159219279248
Pubmed

Postnatal regulation of limb proprioception by muscle-derived neurotrophin-3.

NTF3 NEFH

2.08e-052159211241389
Pubmed

Abnormalities in the cerebellar levels of trophic factors BDNF and GDNF in pcd and lurcher cerebellar mutant mice.

GRID2 AGTPBP1

2.08e-052159232109557
Pubmed

Dopamine D1 and D5 receptors modulate spike timing-dependent plasticity at medial perforant path to dentate granule cell synapses.

DRD1 DRD5

2.08e-052159225429131
Pubmed

Specific role of dopamine D1 receptors in spinal network activation and rhythmic movement induction in vertebrates.

DRD1 DRD5

2.08e-052159219204052
Pubmed

Mutation-related differences in exploratory, spatial, and depressive-like behavior in pcd and Lurcher cerebellar mutant mice.

GRID2 AGTPBP1

2.08e-052159226029065
Pubmed

Agonist-dependent and -independent dopamine-1-like receptor signalling differentially regulates downstream effectors.

DRD1 DRD5

2.08e-052159225154512
Pubmed

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.

DMXL2 EPPK1 TRA2B OBSCN IQGAP1 LRPPRC CCT5 CSTF3 PLEC

2.45e-05333159932665550
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

SMG1 GBF1 TRA2B KIF1A MYO9A BAG5 CSTF3 CHD6 AGTPBP1 EPHA4

2.56e-054201591028065597
Pubmed

Complete mutation analysis panel of the 39 human HOX genes.

HOXA6 HOXC5 HOXC9 HOXD9

2.75e-0538159411857506
Pubmed

Atlas of Hox gene expression in the developing kidney.

HOXA6 HOXC5 HOXC9 HOXD9

2.75e-0538159415042701
Pubmed

Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster.

HOXA6 HOXC5 HOXC9 HOXD9

3.05e-0539159433257809
Pubmed

Organization and expression of mouse Hox3 cluster genes.

HOXA6 HOXC5 HOXC9

3.29e-051415938099712
Pubmed

Hox-1.11 and Hox-4.9 homeobox genes.

HOXA6 HOXC5 HOXD9

3.29e-051415931348361
Pubmed

Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.

MYO5B MYO9A MYO9B

3.29e-051415938022818
Pubmed

Quantification of Hox and surfactant protein-B transcription during murine lung development.

HOXA6 HOXC5 HOXC9 HOXD9

3.38e-0540159419204410
Pubmed

Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates.

HOXA6 HOXC5 HOXC9 HOXD9

3.73e-0541159432479258
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

DMXL2 TRA2B NFASC GRIA3 SIPA1 MAPK8IP3 IQGAP1 SPTBN4 NEFH LRPPRC CELSR2 DCHS1 MACF1 SSH2 EPHA4

3.87e-059631591528671696
Pubmed

Reduction of Hox gene expression by histone H1 depletion.

HOXA6 HOXC5 HOXC9 HOXD9

4.52e-0543159422701719
Pubmed

Nomenclature for human homeobox genes.

HOXA6 HOXC5 HOXC9 HOXD9

4.95e-054415941973146
Pubmed

Hox genes and the evolution of vertebrate axial morphology.

HOXC5 HOXC9 HOXD9

5.03e-051615937768176
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

HDAC6 TRA2B UBE4B MYO9A MYO9B RPS15 IQGAP1 CRNKL1 LRPPRC CCT5 RECQL4 SMARCA2 MACF1 PLCG2 PLEC WDR13 VARS1 PHIP

5.05e-0513531591829467282
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

PLOD3 KIF1A RPS15 COMTD1 AP3B1 LRCH3 IQGAP1 HMG20B CRNKL1 CELSR1 CCT5 SURF6 SMARCA2 CSTF3 MACF1 CHD6 ZBTB11 IMP3 VARS1

5.79e-0514971591931527615
Pubmed

Characterization of 'non-N-methyl-D-Aspartate' binding sites for gacyclidine enantiomers in the rat cerebellar and telencephalic structures.

GRID2 AGTPBP1

6.21e-053159211279275
Pubmed

Identification of a cyclic adenosine 3',5'-monophosphate-dependent protein kinase phosphorylation site in the carboxy terminal tail of human D1 dopamine receptor.

DRD1 DRD5

6.21e-05315927609904
Pubmed

Screening of candidate genes at GLC3B and GLC3C loci in Chinese primary congenital glaucoma patients with targeted next generation sequencing.

ZC2HC1C VPS13D

6.21e-053159236193031
Pubmed

Activation of D1/D5 dopamine receptors protects neurons from synapse dysfunction induced by amyloid-beta oligomers.

DRD1 DRD5

6.21e-053159221115476
Pubmed

Dopamine D₁-like receptors regulate the α₁A-adrenergic receptor in human renal proximal tubule cells and D₁-like dopamine receptor knockout mice.

DRD1 DRD5

6.21e-053159225339698
Pubmed

Motor neuron columnar fate imposed by sequential phases of Hox-c activity.

HOXC5 HOXC9

6.21e-053159214586461
Pubmed

The AP-3 complex required for endosomal synaptic vesicle biogenesis is associated with a casein kinase Ialpha-like isoform.

AP3B1 AP3B2

6.21e-053159210930456
Pubmed

The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.

CELSR1 CELSR2

6.21e-053159211677057
Pubmed

Target neuron controls the integrity of afferent axon phenotype: a study on the Purkinje cell-climbing fiber system in cerebellar mutant mice.

GRID2 AGTPBP1

6.21e-05315927891151
Pubmed

The protein-tyrosine phosphatase PTPMEG interacts with glutamate receptor delta 2 and epsilon subunits.

GRID2 PTPN4

6.21e-053159210748123
Pubmed

The dopaminergic D1 receptor modulates the hyperactivity of Bapa mutant mice.

DRD1 KMT2D

6.21e-053159237394124
Pubmed

Course and targets of the calbindin D-28k subpopulation of primary vestibular afferents.

GRID2 AGTPBP1

6.21e-05315929831049
Pubmed

Plakins: a family of versatile cytolinker proteins.

EPPK1 PLEC

6.21e-053159211854008
Pubmed

Calcium signaling by dopamine D5 receptor and D5-D2 receptor hetero-oligomers occurs by a mechanism distinct from that for dopamine D1-D2 receptor hetero-oligomers.

DRD1 DRD5

6.21e-053159219171671
Pubmed

Dopamine and angiotensin type 2 receptors cooperatively inhibit sodium transport in human renal proximal tubule cells.

DRD1 DRD5

6.21e-053159222710646
Pubmed

Differential D1 and D5 receptor regulation and degradation of the angiotensin type 1 receptor.

DRD1 DRD5

6.21e-053159218172057
Pubmed

Vestibular ganglion neurons survive the loss of their cerebellar targets.

GRID2 AGTPBP1

6.21e-05315929926858
Pubmed

Dopamine receptor genes and migraine with and without aura: an association study.

DRD1 DRD5

6.21e-053159212047334
Pubmed

The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2.

AP3B1 PRF1

6.21e-053159223403622
Pubmed

Receptor subtypes involved in the presynaptic and postsynaptic actions of dopamine on striatal interneurons.

DRD1 DRD5

6.21e-053159212867509
Pubmed

Vertebrate homeobox gene nomenclature.

HOXA6 HOXC5 HOXC9 HOXD9

6.44e-054715941358459
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

KIF1A RPS15 RNF40 ZFX IQGAP1 CCT5 SCN9A CHD6 PHIP MAST3

7.16e-054751591031040226
Pubmed

Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons.

HOXA6 HOXC5 HOXC9

7.27e-0518159323359544
Pubmed

New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice.

HOXA6 HOXC5 HOXC9 HOXD9

8.22e-0550159428188179
Pubmed

Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1.

SFI1 SNAP29 CELSR1

1.01e-0420159316009131
Pubmed

The mouse PcG gene eed is required for Hox gene repression and extraembryonic development.

HOXA6 HOXC5 ASCL2

1.01e-0420159312370779
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

PLOD3 OBSCN CCDC187 CRNKL1 VPS13D CCT5 SURF6 SCN9A EIF2AK4 CSPP1

1.04e-044971591036774506
Pubmed

GABAA/benzodiazepine receptor gamma 2 subunit gene expression in developing normal and mutant mouse cerebellum.

GRID2 AGTPBP1

1.24e-04415928395631
Pubmed

N-Acetylglucosaminyl transferase regulates the expression of the sulfoglucuronyl glycolipids in specific cell types in cerebellum during development.

GRID2 AGTPBP1

1.24e-04415928910533
Pubmed

Low affinity binding of the classical D1 antagonist SCH23390 in rodent brain: potential interaction with A2A and D2-like receptors.

DRD1 DRD5

1.24e-044159216962565
Pubmed

Isolation and regional localization of the murine homeobox-containing gene Hox-3.3 to mouse chromosome region 15E.

HOXC5 HOXC9

1.24e-04415922570032
Pubmed

Expression of Somatostatin, cortistatin, and their receptors, as well as dopamine receptors, but not of neprilysin, are reduced in the temporal lobe of Alzheimer's disease patients.

DRD1 DRD5

1.24e-044159220164562
Pubmed

Hereditary Sensory and Autonomic Neuropathy Type II

KIF1A SCN9A

1.24e-044159221089229
Pubmed

Association study between the phenotype migraine without aura-panic disorder and dopaminergic receptor genes.

DRD1 DRD5

1.24e-044159212967601
Pubmed

BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity.

MYO9A MYO9B

1.24e-044159215644318
Pubmed

Dopamine genes and pathological gambling in discordant sib-pairs.

DRD1 DRD5

1.24e-044159217394052
GeneFamilyEF-hand domain containing|Plakins

EPPK1 MACF1 PLEC

1.04e-0581053939
GeneFamilyHOXL subclass homeoboxes

EVX2 HOXA6 HOXC5 HOXC9 HOXD9

1.26e-05521055518
GeneFamilyMyosins, class IX

MYO9A MYO9B

3.34e-05210521103
GeneFamilyAdhesion G protein-coupled receptors, subfamily C|CELSR cadherins

CELSR1 CELSR2

9.98e-0531052913
GeneFamilyAdhesion G protein-coupled receptors, subfamily C|CELSR cadherins

CELSR1 CELSR2

9.98e-05310521189
GeneFamilyDopamine receptors

DRD1 DRD5

3.30e-0451052181
GeneFamilyFibronectin type III domain containing

OBSCN NFASC PTPRM ELFN1 TRIM36 EPHA4

3.42e-041601056555
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

DRD5 MYO5B NTF3 RBP4 SFI1 SOX13 ITPKA NEFH ESYT3 RNF220 SLC9A2 SHROOM1 P2RX2 GLDC ELFN1 ASCL2 HS3ST6 PLCG2 TRIM36 SCIN PIK3R5

2.33e-06107415921M1941
CoexpressionBENPORATH_ES_WITH_H3K27ME3

DRD5 MYO5B RIMKLA FBXL14 RBP4 HLA-F ITPKA HOXA6 SPTBN4 NEFH SLC9A2 HOXC5 HOXD9 NKX2-1 ASCL2 PLEC TRIM36 SCIN EPHA4 KLHL17

1.46e-05111515920M10371
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

SMG1 GBF1 UBE4B NBEAL1 MYO9B CELSR2 MACF1 NEURL1B

1.48e-051801598M8239
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO5B RBP4 SLC24A3 GRID2 MYO3A SLC9A2 PTPRM ELFN1

3.65e-07186159896f6603cc75fa1ffc2a2fdb94ec0ec09498e540a
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G SMG1 APPBP2 SFI1 COMTD1 CREBZF PLCG2

2.78e-061711597e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DRD1 NTF3 NFASC GRID2 PLEKHG2 SOX13 NEURL1B

4.67e-06185159751dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DRD1 NTF3 NFASC GRID2 PLEKHG2 SOX13 NEURL1B

4.67e-061851597a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO5B SLC24A3 RPP25 SLC9A2 PTPRM ELFN1 SCN9A

6.17e-0619315974979862c0c16e6b4baa4c79894f1d237c861f5a5
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO5B RBP4 SLC24A3 GRID2 SLC9A2 PTPRM ELFN1

6.38e-0619415971bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMXL2 TRA2B MYO9B NAIP PLEKHG2 SSH2 AGTPBP1

6.38e-061941597dfe0ece81922bfd7c6673726d3ea2365cbdb5513
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

KIF1A RIMKLA USHBP1 ASCL2 AP3B2 HS3ST6 OTULINL

6.38e-061941597ccff0b5814f5de2d42720018e7f5dc5dcdafb568
ToppCelldroplet-Heart-HEART-1m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G SLC4A1 VPS13D SHROOM1 OTULINL TRIM36

6.44e-061271596983489a69d3b1f1fe21110a862ac1dba53e9d31c
ToppCell10x5'v1-week_14-16-Myeloid_monocytic|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MYO1G RNF130 DMXL2 AZU1 NAIP RPS15 OTULINL

7.53e-0619915975caaf66b6cddcc8f0d0aee3c9ba80d02075e87e5
ToppCell10x5'v1-week_14-16-Myeloid_monocytic-monocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MYO1G RNF130 DMXL2 AZU1 NAIP RPS15 OTULINL

7.53e-0619915977f5d47e49776114d9f4a42017fead9eeb415a94c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

OBSCN SLC24A3 CCDC85A SPTBN4 SCN9A PLEC ALDOC

7.78e-0620015975c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

OBSCN SLC24A3 CCDC85A SPTBN4 SCN9A PLEC ALDOC

7.78e-06200159761d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp4_Mab21l1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NRTN SLC24A3 RPP25 CDH20 ELFN1 PLCG2

9.53e-0613615969cf076597e6fd9390850fda259daa13022f15893
ToppCellP15-Epithelial-epithelial_progenitor_cell-epi_progenitor|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPINT2 NKX2-1 P2RX2 ELFN1 ASCL2 PLCG2

2.32e-051591596a4bfd59c53237964fc24a24de5c1925fdd01db99
ToppCelldroplet-Heart-nan-24m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G SLC4A1 ESYT3 OTULINL DNA2 ALDOC

2.48e-0516115967e60001637ef0f6fc67ef8a36ab80ebb25b0b0ab
ToppCelldroplet-Lung-nan-18m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G PLOD3 PLCG2 SSH2 OTULINL DNA2

2.85e-0516515960fbdd043e11aa8dbff4cd3a4da1b2feb49878a09
ToppCelldroplet-Lung-nan-18m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G PLOD3 PLCG2 SSH2 OTULINL DNA2

2.85e-051651596e32697321cef424c2ad4e11ee9da3e510d5ce505
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

HOXA6 FSTL1 ANAPC2 VARS1 ZNF654 EPHA4

3.05e-051671596b5d15773be32cd277125fd3b4056a8fefaefa5ec
ToppCellFrontal_cortex-Neuronal-Inhibitory|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NRTN SLC24A3 RPP25 ELFN1 SCN9A CHD6

3.26e-05169159678eb70dd916724e476eabccf18fb7fcec4210308
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|390C / Donor, Lineage, Cell class and subclass (all cells)

MYO1G HLA-F PTPN4 ASCL2 PRF1 MAST3

3.48e-051711596d6d8ea45b443d95f64720c9bc07d324148f5b239
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NRTN SLC24A3 RPP25 CDH20 KCNT2 ELFN1

3.48e-0517115965efd15300f865ebf651e0888265cbd717bc3b9d3
ToppCellfacs-Lung-EPCAM-18m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G KIF1A MYO9B MREG SCIN PIK3R5

3.60e-0517215967c085c02b59e24e2a2cd393b5e692f9fb19257fe
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G KIF1A MYO9B MREG SCIN PIK3R5

3.60e-051721596c5caae0b21e35a2d5dcd898fbfa1ef33f92c019f
ToppCellIonocyte-iono-2|World / Class top

IQGAP1 ADHFE1 PTPRM SURF6 PLCG2 NEURL1B

3.72e-051731596e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCellfacs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN GRIA3 ITPKA PTPN4 SLC9A2 FAM83F

4.09e-05176159674f851a398c7562dd713bc0d8d488c0037243112
ToppCellfacs-Marrow-T_cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN GRIA3 ITPKA PTPN4 SLC9A2 FAM83F

4.09e-05176159631b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell3'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRTN FBXL14 TREH NTN5 PLCG2 PIK3R5

4.50e-051791596906555ce2ca264a0215b120c7ff7c9b411de6a34
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HDAC6 BRWD3 ESYT3 FSTL1 PTPRM DCHS1

4.64e-0518015962d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HDAC6 BRWD3 ESYT3 FSTL1 PTPRM DCHS1

4.64e-051801596baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HDAC6 BRWD3 ESYT3 FSTL1 PTPRM DCHS1

4.64e-0518015960f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCellControl-Lymphocytic_NKT-iNKT/MAIT|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO1G SLC24A3 PRF1 PLCG2 OTULINL PIK3R5

5.08e-05183159659e8d07556390828f7557ba3fd2f7d49851498b7
ToppCellControl-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO1G SLC24A3 PRF1 PLCG2 OTULINL PIK3R5

5.08e-0518315962c5707ada3442eb7100a2a5f9438d5a2ac53a9e1
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC85A TBC1D20 PTPN4 PTPRM SCN9A PML

5.08e-051831596e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RBP4 GRID2 FSTL1 PTPRM ELFN1 SCN9A

5.40e-051851596ae53aa2ecfe418a5dbd7d963a995bc06dab94f56
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

DMXL2 GBF1 SFI1 KMT2D MACF1 AGTPBP1

5.40e-051851596a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NRTN RBP4 SLC24A3 RPP25 PTPRM ELFN1

5.40e-051851596739260f8abebaf10a5cc49d91726278579e26170
ToppCelldroplet-Skin|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 KRT32 SLC24A3 FAM83F ASCL2 HS3ST6

5.40e-051851596657fd191ed160f8620d57b33820ec7222806f289
ToppCelldroplet-Bladder-nan-24m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFASC CCDC85A PTPRM USHBP1 EXOC3L1 NEURL1B

5.40e-05185159690caab8d9361a541c5d5121c97c3f1cdffeeae4a
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIF1A RIMKLA NFASC ASCL2 HS3ST6 ACOXL

5.56e-051861596c7983281a290201567b398e9ea6baddb96c692bb
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

DMXL2 GBF1 SFI1 MACF1 DNA2 AGTPBP1

5.56e-0518615968571956890fc9894d766ba294a28e376b4aba428
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYO5B ESYT3 RNF220 NKX2-1 GLDC ACOXL

5.73e-051871596db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellfacs-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYO5B SPINT2 NKX2-1 ELFN1 NTN5 ACOXL

5.73e-051871596a5318c888b334e8695f38971a7d100b93cdaf04b
ToppCellfacs-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYO5B SPINT2 NKX2-1 ELFN1 NTN5 ACOXL

5.73e-05187159664ba0df991eab8b2632751805d758c5f2711f4d7
ToppCellfacs-Heart-LV-3m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRTN OBSCN CHM RPP25 PTPN4 AGTPBP1

5.90e-05188159640ce7125fca6f6b6b5cc1637c87d43c29b08f4f1
ToppCellfacs-Heart-LV-3m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRTN OBSCN CHM RPP25 PTPN4 AGTPBP1

5.90e-051881596ba7f7ce034c0f42742bf2461f68f8d343ee593a5
ToppCell(2)_NK/T-(21)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

MYO1G IQGAP1 SNAP29 ASCL2 PRF1 MACF1

6.08e-051891596b37ad24898a14a4a3b2d6cea2637de2471f76e20
ToppCell(2)_NK/T-(210)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

MYO1G IQGAP1 SNAP29 ASCL2 PRF1 MACF1

6.08e-051891596fa72e87e1e8cd7cbddae7b47e19cf90d181820a7
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NTF3 MCL1 SLC24A3 HS3ST6 SSH2 SCIN

6.08e-0518915961cfc1fe27c4b57b4e52700fa8f679ce172cee5a9
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTF3 NFASC GRID2 PLEKHG2 KCNT2 NEURL1B

6.08e-051891596fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO1G PTPN4 PRF1 MACF1 SSH2 PIK3R5

6.26e-051901596d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO5B RPP25 SLC9A2 PTPRM ELFN1 SCN9A

6.26e-05190159626843ec1d19ac85a50990705353b802745d33e4d
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AZU1 KMT2D SURF6 RECQL4 SCN9A DNA2

6.26e-0519015963f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Neuroendocrine|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFASC NKX2-1 AP3B2 SCN9A HS3ST6 SCIN

6.44e-051911596501d4f6ad389d9ac5051d4247b9bd3da96f713f9
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5B CELSR1 NKX2-1 ELFN1 NTN5 ACOXL

6.44e-051911596c06bbad24e4897b2c3b5015e4de02411ebf75367
ToppCellfacs-Lung-EPCAM-24m-Epithelial-lung_neuroendocrine_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFASC NKX2-1 AP3B2 SCN9A HS3ST6 SCIN

6.44e-0519115968e06cc61eaff1796c2ce014074029408ba88d561
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC GRID2 PLEKHG2 SOX13 KCNT2 NEURL1B

6.44e-0519115967b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellfacs-Lung-EPCAM-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 MYO5B CELSR1 SPINT2 NKX2-1 ACOXL

6.44e-051911596629007189034ee8451411428f1c6cc57daee2d91
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC GRID2 PLEKHG2 SOX13 KCNT2 NEURL1B

6.44e-051911596cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

GBF1 SFI1 IQGAP1 MACF1 DNA2 AGTPBP1

6.44e-0519115969454f642c3621370fa23640b631301346b300950
ToppCellfacs-Lung-nan-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5B CELSR1 NKX2-1 ELFN1 NTN5 ACOXL

6.44e-0519115965f43f98cfe7a08d61ed55f34808fabfe47f1ac2e
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

MYO5B NBEAL1 MREG CELSR2 NKX2-1 ACOXL

6.44e-051911596d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B MYO3A CELSR1 SPINT2 NKX2-1 GLDC

6.63e-05192159625378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EPPK1 MYO5B MREG NKX2-1 GLDC ACOXL

6.63e-05192159639804d9ddc67c1b41887752df2503389eae44a1a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RBP4 SLC24A3 SLC9A2 PTPRM ELFN1 SCN9A

6.63e-051921596dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCellfacs-Lung-nan-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 MYO5B CELSR1 NKX2-1 ELFN1 ACOXL

6.63e-051921596cca2d0fedfbd946c54d6f4fc45887117c8dae58a
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AZU1 KMT2D SURF6 RECQL4 SCN9A DNA2

6.63e-051921596c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RBP4 SLC24A3 GRID2 SLC9A2 PTPRM ELFN1

6.83e-051931596d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO5B RBP4 SLC24A3 SLC9A2 PTPRM ELFN1

6.83e-051931596010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO5B RBP4 SLC24A3 SLC9A2 PTPRM ELFN1

6.83e-0519315962189da4b727e25e62669d7b9257f06493be21a27
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO5B SLC24A3 RPP25 PTPRM ELFN1 SCN9A

6.83e-05193159653bcd50892c379b2a571751f6eb1062436339fe7
ToppCellfacs-Trachea-24m-Epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPPK1 MYO5B CELSR1 SPINT2 CELSR2 NKX2-1

6.83e-051931596ec49a83b24371579d4ad46aad91c25115aa226f9
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MYO5B RIMKLA CELSR1 NKX2-1 ASCL2 SCN9A

6.83e-051931596aa10924b203c71e65fdbd2b90ba131dbd362d8b1
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC24A3 RPP25 SPINT2 PTPRM ELFN1 ALDOC

6.83e-0519315969f9eb241b0b82a6f12de6921c3acf6fed7cf65bb
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC85A TBC1D20 PTPRM SCN9A SMARCA2 EXOC3L1

6.83e-051931596aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC85A TBC1D20 PTPRM SCN9A SMARCA2 EXOC3L1

6.83e-051931596c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 SFI1 LRCH3 ELFN1 MACF1 PLCG2

6.83e-0519315969337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RBP4 SLC24A3 GRID2 SLC9A2 PTPRM ELFN1

6.83e-051931596e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RBP4 SLC24A3 GRID2 SLC9A2 PTPRM ELFN1

6.83e-051931596658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCellfacs-Lung-3m-Epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPPK1 MYO5B CELSR1 SPINT2 NKX2-1 ACOXL

6.83e-051931596db5e43e0b571737e7006365bdf0575340b8b900b
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-1|TCGA-Stomach / Sample_Type by Project: Shred V9

CCDC187 SFI1 HMG20B SPTBN4 KLHL17

6.83e-0511915955d5fcddb5723e7a94bfcf56e165a980fa450b789
ToppCellCOVID-19-Heart-Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

RNF130 DMXL2 NAIP SCN9A OTULINL PIK3R5

7.02e-051941596f09675cd472200363c458952f00d2e41990800ee
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO5B RBP4 SLC24A3 GRID2 SLC9A2 ELFN1

7.02e-05194159683863da11dfbe59b2d0a2c08db40b537c150588c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO5B SLC24A3 RPP25 SLC9A2 PTPRM ELFN1

7.02e-05194159602a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MYO5B MREG ESYT3 NKX2-1 GLDC ACOXL

7.02e-051941596c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYO1G DMXL2 MYO9B NAIP PLEKHG2 PIK3R5

7.02e-0519415963043f6230fa723037c8cf7123f611ae847b39fd4
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO5B SLC24A3 RPP25 SLC9A2 PTPRM ELFN1

7.02e-051941596e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTF3 NFASC SLC24A3 FSTL1 KCNT2 NEURL1B

7.02e-051941596e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B RIMKLA NFASC CELSR1 NKX2-1 SCN9A

7.02e-051941596b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCellCOVID-19_Severe-CD8+_Tem|COVID-19_Severe / Disease condition and Cell class

MYO1G PTPN4 PTPRM ASCL2 PRF1 MACF1

7.22e-051951596ff7ae62393e1c858a10592db8e6d9f36b8bae396
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SLC9A2 USHBP1 SCN9A PLCG2 SCIN ACOXL

7.43e-051961596a4cc02ea41479d24044bd2ca6441f85d683c0ca9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTF3 NFASC GRID2 FSTL1 KCNT2 NEURL1B

7.43e-051961596b8759e6231e0254797d6c30930407b79440c57bb
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SLC9A2 USHBP1 SCN9A PLCG2 SCIN ACOXL

7.43e-05196159650aaca81b593ff71790bb75403b2e4c3ab03a6d2
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO5B SLC24A3 RPP25 SLC9A2 PTPRM ELFN1

7.43e-0519615967af6c5147ac859353504d19727dbe24f63a29dd4
ToppCellT_cells-CTLs|World / Immune cells in Kidney/Urine in Lupus Nephritis

MYO1G PTPN4 ASCL2 PRF1 MACF1 PIK3R5

7.64e-0519715962de34e20915a247bee75aa40495e23c20bb23e18
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

MYO1G DMXL2 MYO9B NAIP SSH2 PIK3R5

7.64e-051971596a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYO1G DMXL2 MYO9B NAIP SSH2 PIK3R5

7.86e-051981596ea34096bee852a7e996f097fa279381afa8f86ff
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DCDC1 AZU1 CCDC187 FETUB MYO3A MORN5

7.86e-051981596f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

SMG1 DMXL2 MYO9B HLA-F MCL1 PLCG2

7.86e-05198159661ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellCOVID-19-lung|COVID-19 / Disease (COVID-19 only), tissue and cell type

DMXL2 MYO9B HLA-F NKX2-1 PIK3R5 ACOXL

8.08e-051991596155b03b859157013e9142e9248551369127d9204
DrugNizatidine [76963-41-2]; Up 200; 12uM; PC3; HT_HG-U133A

SPAM1 KIF1A KRT32 MYO9B ITPKA HMG20B VPS13D SLC9A2 HOXC5 PRF1 FUT7

1.39e-07196159116305_UP
DrugTolbutamide [64-77-7]; Down 200; 14.8uM; HL60; HT_HG-U133A

MCL1 SIPA1 CREBZF MAPK8IP3 EXOC5 SMARCA2 FUT7 ALDOC CSPP1 ZNF654

1.19e-06195159102359_DN
DrugLithocholic acid [434-13-9]; Up 200; 10.6uM; MCF7; HT_HG-U133A

DRD1 SPAM1 TSGA10 ZC2HC1C SFI1 HOXC5 AP3B2 SMARCA2 FUT7 MAST3

1.37e-06198159103433_UP
DrugDeltaline [6836-11-9]; Up 200; 7.8uM; MCF7; HT_HG-U133A

NTF3 ZC2HC1C SFI1 CREBZF SLC9A2 TRIM36 PIK3R5 PML PSD4

1.10e-0519815993831_UP
DrugPepstatin A [26305-03-3]; Up 200; 5.8uM; MCF7; HT_HG-U133A

MYO9A SLC24A3 SFI1 SOX13 ZFX HOXC5 CSTF3 MACF1 PML

1.14e-0519915993264_UP
DiseaseNeuropathy, Hereditary Sensory And Autonomic, Type IIA

KIF1A SCN9A

1.63e-0441552C2752089
DiseaseHereditary sensory and autonomic neuropathy type 2

KIF1A SCN9A

1.63e-0441552cv:C5574675
DiseaseNeuropathy, hereditary sensory and autonomic, type 2A

KIF1A SCN9A

1.63e-0441552cv:C2752089
DiseaseNEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIA

KIF1A SCN9A

1.63e-0441552201300
Diseaselymphocyte count

MYO1G EPPK1 GBF1 TRA2B UBE4B SFI1 SLC4A1 IQGAP1 HOXA6 PTPN4 PRF1 SURF6 SSH2 PLEC NEURL1B FUT7 VARS1 ACOXL PSD4

2.56e-04146415519EFO_0004587
Diseasestanniocalcin-1 measurement

CELSR2 B4GALNT3

7.52e-0481552EFO_0020753
DiseasePARTINGTON X-LINKED MENTAL RETARDATION SYNDROME

GRIA3 BRWD3

7.52e-0481552C0796250
Diseasethyroid gland papillary carcinoma (is_implicated_in)

KMT2D NKX2-1

1.20e-03101552DOID:3969 (is_implicated_in)
Diseasecolorectal cancer, hormone replacement therapy

TRA2B RBP4 SLC24A3 LRPPRC

1.21e-03881554EFO_0003961, MONDO_0005575
Disease3-methylglutarylcarnitine (2) measurement

MREG GLDC

1.46e-03111552EFO_0800074
DiseaseHereditary Motor and Sensory-Neuropathy Type II

KIF1A SCN9A

2.06e-03131552C0270914
DiseaseCD209 antigen measurement

CELSR2 SURF6

2.39e-03141552EFO_0008077
Diseaseneutrophil measurement

SPAM1 EPPK1 AZU1 SSH2 PLEC

2.49e-031771555EFO_0803548
Diseaseunipolar depression, response to escitalopram, response to citalopram, mood disorder

SLC24A3 CSTF3

2.75e-03151552EFO_0003761, EFO_0004247, EFO_0006329, EFO_0007871
DiseaseChronic Lymphocytic Leukemia

RPS15 PLCG2 ACOXL

3.05e-03551553C0023434
Diseaseplatelet-to-lymphocyte ratio

MYO1G HLA-F SLC4A1 IQGAP1 PTPN4 PLEC VARS1

3.17e-033631557EFO_0008446
Diseaseimmature platelet measurement

MYO1G MYO9B DCAF5 PLEC

3.64e-031191554EFO_0803541
Diseasechronic lymphocytic leukemia

KRT32 SFI1 ASCL2 ACOXL

3.64e-031191554EFO_0000095
Diseasealcohol use disorder (implicated_via_orthology)

DRD1 DRD5 SMARCA2 SSH2 PSD4

3.76e-031951555DOID:1574 (implicated_via_orthology)
Diseaseatopic asthma

ITPKA SLC9A2 GLDC NFKBIL1 OTULINL

4.10e-031991555EFO_0010638

Protein segments in the cluster

PeptideGeneStartEntry
VAFQLRSYVQRLQER

USHBP1

421

Q8N6Y0
VRTNRARDIRRYLET

NAIP

581

Q13075
QLARLGQYRSREVQR

EXOC3L1

46

Q86VI1
RRRQLGEIQLTVRYV

ESYT3

751

A0FGR9
RLQRRVEELCQRVYS

RNF40

201

O75150
RLNENRIRSVQYASL

ELFN1

66

P0C7U0
ELRSRRLQEVYRQQR

CCDC187

666

A0A096LP49
RYLRTREDTVRQIVA

ANAPC2

426

Q9UJX6
ARRRAVIEVQTLITY

BAG5

331

Q9UL15
TRRRYETQVQTRLQT

EIF2AK4

1546

Q9P2K8
VPVQRELLRRRYQSS

SLC4A1

336

P02730
LNQRSRGRYQLQRIV

B4GALNT3

681

Q6L9W6
RGRYQLQRIVNVEKR

B4GALNT3

686

Q6L9W6
RRLYRQVLFSADDRV

ALDOC

56

P09972
DQVRRYRTAFTREQI

EVX2

186

Q03828
HIQADRLRYRNVIQR

AP4B1

21

Q9Y6B7
TDLNTIRRRLENRFY

BRWD3

1186

Q6RI45
VVDNYIRSRRDIRSL

APPBP2

21

Q92624
IGSYERHQIERRRLQ

DMXL2

2121

Q8TDJ6
RTQRRLDRENVAVYN

CELSR1

951

Q9NYQ6
LRRLDRENVAQYVLR

CELSR2

876

Q9HCU4
RIYRIAQKQIRRIAA

DRD1

216

P21728
NARRAVDRGYVQVLL

AGTPBP1

236

Q9UPW5
FRERVLQRGLVARIY

ACOXL

441

Q9NUZ1
QNYDIRDRTRFIRQL

AP3B1

566

O00203
QNYDIRDRARFTRQL

AP3B2

571

Q13367
TLRSAVEYIRALQRL

ASCL2

91

Q99929
LINDIARDIRNQRRY

IQGAP1

1481

P46940
RRKRRVLFSQAQVYE

NKX2-1

161

P43699
SQIREIHLRRYNLRR

NBEAL1

1936

Q6ZS30
RVQYRQISRAVLITD

CHM

446

P24386
RRIREDYPQVQILRA

RIMKLA

11

Q8IXN7
TRIYRIAQVQIRRIS

DRD5

246

P21918
IRYTNARDRNQRRLG

RNF130

221

Q86XS8
RRRYCQVLNAVRIIQ

IQCF1

141

Q8N6M8
RVALRNLLRRYNQSE

HLA-F

96

P30511
RTYNVRASELARDRQ

PTPN4

11

P29074
TLDARIARLAQYRAL

NRTN

46

Q99748
RDAQERSRAALQRYL

ARIH1

401

Q9Y4X5
LKFDRNRVRIRNVAY

PLOD3

231

O60568
VRTARVLDREQRDRY

DCHS1

101

Q96JQ0
LMEIRANYARIRRQQ

DCDC1

1746

M0R2J8
FNRYLTRRRRIEIAN

HOXC5

176

Q00444
RRYEVARVLNLTERQ

HOXC9

221

P31274
VERTRREAQLAALQY

LRCH3

476

Q96II8
FNRYLTRRRRIEIAN

HOXA6

176

P31267
RAYRRLNRTVAELVQ

MAGEF1

71

Q9HAY2
SSARREQKREQYRQV

MAPK8IP3

636

Q9UPT6
RLASYLTRVRQLEQE

KRT32

106

Q14532
RSYRIVRTAARNTDI

EPHA4

486

P54764
VLRLNRVNDAQEYRR

FETUB

61

Q9UGM5
VIAEAFRYLRRQRVD

GRIA3

316

P42263
NRYRDTLRRAILVMN

GRID2

221

O43424
RNLQDLARIYIRRTL

PCMTD1

241

Q96MG8
LARIYIRRTLRNFIN

PCMTD1

246

Q96MG8
RREALRRALSQYLTD

PRF1

356

P14222
ENQRITAVRRVYQRG

CSTF3

161

Q12996
RRLAEQRARIQQEYE

CSPP1

801

Q1MSJ5
VVSNFQERQLRARLY

FUT7

176

Q11130
AASRQQRLSALRRYQ

DCAF5

506

Q96JK2
SERYARLERAQVLVN

MACF1

1896

O94854
TRDRRYEVARILNLT

HOXD9

311

P28356
ANSRLIITQVRRDYL

LRPPRC

1106

P42704
NDIVKQGYVRIRSRR

DOK5

6

Q9P104
ITQQRLNLYRRSERQ

KCNT2

1036

Q6UVM3
LYSSCRQLRRRQEEL

PLCG2

1196

P16885
EQGALRRYLRVQQVR

NFKBIL1

326

Q9UBC1
ELLRQQRRYNSPRVL

NTF3

91

P20783
RRVQILSLRRSLSYV

FBXL14

71

Q8N1E6
RQRRQALLRVYVIQE

IQCF3

76

P0C7M6
LINERQRLINSRAYT

SLC24A3

351

Q9HC58
LLNSERYARLERAQV

MACF1

5766

Q9UPN3
RYARLERAQVLVNQF

MACF1

5771

Q9UPN3
RQVRRDNYDALRSVL

OTULINL

131

Q9NUU6
RRYLNRLQQIRDTLE

ITPKA

371

P23677
LRSRTRAQAYRERDI

OBSCN

6501

Q5VST9
VRNRRLGVLYRAVQL

P2RX2

36

Q9UBL9
YRRQLQARTTELEAL

NEFH

321

P12036
RNQLIRVILYNRTRL

NFASC

436

O94856
FVQLRADYRSARLAR

EXOC5

691

O00471
ETERTRNLYRRLLQR

CRNKL1

691

Q9BZJ0
TRRRYVRVATLDGNL

KLHL17

471

Q6TDP4
ARLRRLVTVYQRCNR

CHD6

1396

Q8TD26
RLDREERAQYTLRAQ

CDH20

121

Q9HBT6
ERAQYTLRAQALDRR

CDH20

126

Q9HBT6
VVCYQSNRDELRRRI

FSTL1

111

Q12841
NERIRRDVRVYISLL

COMTD1

236

Q86VU5
RIITAFYNEARARAR

DNAJC4

191

Q9NNZ3
TLSYVRQLEARVRQL

CCDC85A

416

Q96PX6
SQKQILERCRAVIRY

CSAD

66

Q9Y600
VYLVRHRDTRQRFAI

MAST3

381

O60307
TRYNQLSRAVRELAR

IMP3

46

Q9NV31
ARRQVRMQALTYLQR

GBF1

1556

Q92538
LYVRNRVREAIRVSK

SPAM1

276

P38567
VMRRQLYAVNRRLRA

FATE1

136

Q969F0
RYAQQKHRIRRVLIV

HDAC6

236

Q9UBN7
LGAYDLRRRERQSRQ

AZU1

81

P20160
RSQVVLYTLLSQERR

DNA2

311

P51530
YRVRRNMIQSRLTQE

POLR3E

661

Q9NVU0
LSLSEYRRRRQQRQA

PPRC1

751

Q5VV67
RVPQALVRRLQEFYR

HS3ST6

311

Q96QI5
QRRRRRVLDTSVAYV

KIF1A

1341

Q12756
RQSLEIISRYLREQA

MCL1

176

Q07820
VDIYNCVRELRSRRV

PTPRM

1121

P28827
RARVAYLLRQLQRAA

ADHFE1

6

Q8IWW8
LHQVTRLRYRSVREV

RPP25

91

Q9BUL9
GYVRFLNERREQIRT

HMG20B

76

Q9P0W2
RAVRSLRADYNLTRI

VARS1

1116

P26640
YQGRVRSILREVAAR

SFI1

661

A8K8P3
IVERYRQAARAATAI

TRIM36

141

Q9NQ86
RNRVTDRYFRIQEVL

MRPL20

11

Q9BYC9
REYRLQARIAHRIQE

SMARCA2

346

P51531
LANTRAYQQSRRARI

SAMD8

366

Q96LT4
RLAVRVLAVYKQRAQ

NTN5

386

Q8WTR8
RLFQVRRNLASITRI

SCIN

511

Q9Y6U3
YGRVQARERQALARL

RECQL4

1056

O94761
NYDIHTLRQVRREVR

MREG

91

Q8N565
SLQRRLSVYRQIVDA

PML

111

P29590
QRYAADINSRLIRQV

SMG1

2711

Q96Q15
LRRYRQREVTLGQVA

EPPK1

851

P58107
ETQERERILYQFSRR

PSD4

651

Q8NDX1
RRYRLRQNVKNISSI

SCN9A

1901

Q15858
RQQYLRQEVLRRAEA

SNAP29

41

O95721
YRVIVRTTQLRTLRG

SIPA1

261

Q96FS4
YRQRLQGAQRRVLRE

SHROOM1

141

Q2M3G4
LCVIRNLIRDNRVVY

CCT5

406

P48643
FRTQYIRRRSQLLRE

WDR13

26

Q9H1Z4
YRQLLERLQARQSRL

SURF6

236

O75683
YQTFLRVRANRQTRL

RNF220

301

Q5VTB9
LQLTDFRIRNIRVRS

FAM83F

211

Q8NEG4
RASAREVRQEGRYRV

SLC7A6OS

91

Q96CW6
EQLMQLYSARQRRRL

RPS15

31

P62841
VRAQLSVRQFTLRVR

SWI5

36

Q1ZZU3
LMRTRRQDARQSYVI

SOX13

516

Q9UN79
RLRQRSVNEGAYIRL

ZBTB11

506

O95625
LYQRTRISLLQREAA

NDUFAF3

41

Q9BU61
RRRLRNRAQSYDIQA

PHIP

1306

Q8WWQ0
RLAVRLESTYQNRTR

SSH2

91

Q76I76
VARAYSNLRRLENNR

PIK3R5

531

Q8WYR1
IRELLSRNLYQIRQR

SLC9A2

601

Q9UBY0
SMVYLIRVARRNQER

SPINT2

216

O43291
RQRQEELCLARQYRL

RBP4

171

P02753
YIRRLRAIRELNRTV

UBE4B

776

O95155
IRLYEQVRLRLVAVR

NEURL1B

76

A8MQ27
YRILRSQRLAALNTV

TREH

376

O43280
RVQALQEESRYLRAV

CREBZF

256

Q9NS37
RYGNVNLELVTRIIR

ZNF654

146

Q8IZM8
YDIRRVAAQRDSVLR

SPTBN4

501

Q9H254
RELYQQLQRGERSVR

PLEC

3131

Q15149
YRIQRLKRERLVASN

ZC2HC1C

321

Q53FD0
RERAVQELRRQNYSS

TSGA10

641

Q9BZW7
RRRPDSRQYQTAIII

ZFX

401

P17010
YQQVLLDVRRSLRRF

TBC1D20

96

Q96BZ9
RVRELARLYSERIQQ

PLEKHG2

816

Q9H7P9
RAAQDRDQIYRRRSP

TRA2B

251

P62995
RMRLYDVNRRQLNLT

VPS13D

3251

Q5THJ4
YRLALQTREQHIRRD

GLDC

361

P23378
VTRVVKDYRNRFLRN

MORN5

131

Q5VZ52
YIGTIIRNEVANRRE

KMT2D

5426

O14686
QVAYLGLLENVRVRR

MYO1G

621

B0I1T2
QLRYTGILETARIRR

MYO3A

971

Q8NEV4
QRARQAYQRVRRAAV

MYO5B

826

Q9ULV0
RQRYLELRAAAIVIQ

MYO9A

1091

B2RTY4
RRALERTQAAVYLQA

MYO9B

996

Q13459