Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	PAXIP1 CITED2 SMARCA4 WWTR1 IL17A TAF4 SIX4 TCF20 NFAT5 CDK12 STAT5B PYGO1	4.37e-06	1390	38	12	GO:0045944
GeneOntologyCellularComponent	mCRD-mediated mRNA stability complex	PABPC1 PABPC3	4.80e-05	6	38	2	GO:0106002
Domain	PABC	PABPC1 PABPC3	4.23e-05	5	39	2	PS51309
Domain	PolyA	PABPC1 PABPC3	4.23e-05	5	39	2	SM00517
Domain	PABP_1234	PABPC1 PABPC3	4.23e-05	5	39	2	IPR006515
Domain	PABP_HYD	PABPC1 PABPC3	4.23e-05	5	39	2	IPR002004
Domain	-	PABPC1 PABPC3	4.23e-05	5	39	2	1.10.1900.10
Domain	PABP	PABPC1 PABPC3	4.23e-05	5	39	2	PF00658
Domain	PHD	TRIM33 TCF20 PYGO1	8.44e-04	89	39	3	SM00249
Domain	Znf_PHD	TRIM33 TCF20 PYGO1	9.01e-04	91	39	3	IPR001965
Domain	ZF_PHD_2	TRIM33 TCF20 PYGO1	1.02e-03	95	39	3	PS50016
Domain	RRM_dom_euk	PABPC1 PABPC3	1.05e-03	23	39	2	IPR003954
Domain	RRM_1	PABPC1 PABPC3	1.05e-03	23	39	2	SM00361
Domain	ZF_PHD_1	TRIM33 TCF20 PYGO1	1.05e-03	96	39	3	PS01359
Domain	BROMODOMAIN_1	SMARCA4 TRIM33	2.70e-03	37	39	2	PS00633
Domain	Bromodomain	SMARCA4 TRIM33	2.85e-03	38	39	2	PF00439
Domain	BROMODOMAIN_2	SMARCA4 TRIM33	3.31e-03	41	39	2	PS50014
Domain	AAA+_ATPase	NAV2 RNF213 ABCA12	3.35e-03	144	39	3	IPR003593
Domain	AAA	NAV2 RNF213 ABCA12	3.35e-03	144	39	3	SM00382
Domain	BROMO	SMARCA4 TRIM33	3.47e-03	42	39	2	SM00297
Domain	Bromodomain	SMARCA4 TRIM33	3.47e-03	42	39	2	IPR001487
Domain	-	SMARCA4 TRIM33	3.47e-03	42	39	2	1.20.920.10
Domain	Znf_FYVE_PHD	TRIM33 TCF20 PYGO1	3.55e-03	147	39	3	IPR011011
Domain	p53-like_TF_DNA-bd	NFAT5 STAT5B	5.47e-03	53	39	2	IPR008967
Domain	Zinc_finger_PHD-type_CS	TRIM33 PYGO1	8.13e-03	65	39	2	IPR019786
Domain	PHD	TRIM33 PYGO1	1.07e-02	75	39	2	PF00628
Domain	Znf_PHD-finger	TRIM33 PYGO1	1.18e-02	79	39	2	IPR019787
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	PAXIP1 SMARCA4 TRIM33 TCF20 ACAD11 AFF3	1.73e-07	222	39	6	37071664
Pubmed	Human transcription factor protein interaction networks.	PAXIP1 SMARCA4 TRIM33 TAF4 SIX4 LHX8 TCF20 PABPC1 PABPC3 STAT5B PYGO1	3.14e-07	1429	39	11	35140242
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	CITED2 SMARCA4 SIX4 LHX8 TCF20 NFAT5 STAT5B PYGO1	1.01e-06	709	39	8	22988430
Pubmed	Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells.	PABPC1 PABPC3	1.23e-06	2	39	2	19020299
Pubmed	Functional compensation for the loss of testis-specific poly(A)-binding protein, PABPC2, during mouse spermatogenesis.	PABPC1 PABPC3	1.23e-06	2	39	2	26971890
Pubmed	TAZ suppresses NFAT5 activity through tyrosine phosphorylation.	WWTR1 NFAT5	1.23e-06	2	39	2	23045390
Pubmed	Levels of free PABP are limited by newly polyadenylated mRNA in early Spisula embryogenesis.	PABPC1 PABPC3	1.23e-06	2	39	2	10954604
Pubmed	The promoter of the Poly(A) binding protein 2 (Pabp2) retroposon is derived from the 5'-untranslated region of the Pabp1 progenitor gene.	PABPC1 PABPC3	1.23e-06	2	39	2	10534404
Pubmed	The mouse gene encoding the testis-specific isoform of Poly(A) binding protein (Pabp2) is an expressed retroposon: intimations that gene expression in spermatogenic cells facilitates the creation of new genes.	PABPC1 PABPC3	1.23e-06	2	39	2	9732454
Pubmed	Nucleotide sequence of a mouse testis poly(A) binding protein cDNA.	PABPC1 PABPC3	1.23e-06	2	39	2	1630930
Pubmed	Developmental expression of poly(A) binding protein mRNAs during spermatogenesis in the mouse.	PABPC1 PABPC3	1.23e-06	2	39	2	7893484
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	SMARCA4 SIX4 TCF20 CDK12	2.33e-06	83	39	4	28794006
Pubmed	Interaction network of human early embryonic transcription factors.	PAXIP1 SMARCA4 TRIM33 TAF4 SIX4 TCF20	2.49e-06	351	39	6	38297188
Pubmed	Embryonic Poly(A)-Binding Protein Is Required During Early Stages of Mouse Oocyte Development for Chromatin Organization, Transcriptional Silencing, and Meiotic Competence.	PABPC1 PABPC3	3.67e-06	3	39	2	26134869
Pubmed	Human testis expresses a specific poly(A)-binding protein.	PABPC1 PABPC3	3.67e-06	3	39	2	11328870
Pubmed	Superovulation alters embryonic poly(A)-binding protein (Epab) and poly(A)-binding protein, cytoplasmic 1 (Pabpc1) gene expression in mouse oocytes and early embryos.	PABPC1 PABPC3	3.67e-06	3	39	2	25034140
Pubmed	Epab is dispensable for mouse spermatogenesis and male fertility.	PABPC1 PABPC3	3.67e-06	3	39	2	24599567
Pubmed	Differential 3' Processing of Specific Transcripts Expands Regulatory and Protein Diversity Across Neuronal Cell Types.	PABPC1 PABPC3	3.67e-06	3	39	2	29578408
Pubmed	SIRT1 Functions as a Negative Regulator of Eukaryotic Poly(A)RNA Transport.	PABPC1 PABPC3	3.67e-06	3	39	2	28756945
Pubmed	The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.	PABPC1 PABPC3	3.67e-06	3	39	2	26843391
Pubmed	Domain-functional analyses of PIWIL1 and PABPC1 indicate their synergistic roles in protein translation via 3'-UTRs of meiotic mRNAs.	PABPC1 PABPC3	3.67e-06	3	39	2	29701755
Pubmed	Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs.	PABPC1 PABPC3	3.67e-06	3	39	2	21940797
Pubmed	Translation repression via modulation of the cytoplasmic poly(A)-binding protein in the inflammatory response.	PABPC1 PABPC3	3.67e-06	3	39	2	28635594
Pubmed	The mouse Y-box protein, MSY2, is associated with a kinase on non-polysomal mouse testicular mRNAs.	PABPC1 PABPC3	3.67e-06	3	39	2	10076007
Pubmed	Epab and Pabpc1 are differentially expressed in the postnatal mouse ovaries.	PABPC1 PABPC3	3.67e-06	3	39	2	25370180
Pubmed	Epab and Pabpc1 are differentially expressed during male germ cell development.	PABPC1 PABPC3	3.67e-06	3	39	2	22814100
Pubmed	Cytoplasmic poly(A)-binding protein 1 (PABPC1) interacts with the RNA-binding protein hnRNPLL and thereby regulates immunoglobulin secretion in plasma cells.	PABPC1 PABPC3	3.67e-06	3	39	2	28611064
Pubmed	A twin UGUA motif directs the balance between gene isoforms through CFIm and the mTORC1 signaling pathway.	PABPC1 PABPC3	3.67e-06	3	39	2	37665675
Pubmed	De novo variants in the PABP domain of PABPC1 lead to developmental delay.	PABPC1 PABPC3	3.67e-06	3	39	2	35511136
Pubmed	Regulation of poly(A) binding protein function in translation: Characterization of the Paip2 homolog, Paip2B.	PABPC1 PABPC3	7.34e-06	4	39	2	16804161
Pubmed	Evolution of complexity in the zebrafish synapse proteome.	PABPC1 PABPC3	7.34e-06	4	39	2	28252024
Pubmed	An embryonic poly(A)-binding protein (ePAB) is expressed in mouse oocytes and early preimplantation embryos.	PABPC1 PABPC3	7.34e-06	4	39	2	15630085
Pubmed	Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP.	PABPC1 PABPC3	7.34e-06	4	39	2	18490513
Pubmed	UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant.	PABPC1 PABPC3	7.34e-06	4	39	2	15314026
Pubmed	Stress granules inhibit apoptosis by reducing reactive oxygen species production.	PABPC1 PABPC3	7.34e-06	4	39	2	23230274
Pubmed	Transthyretin Upregulates Long Non-Coding RNA MEG3 by Affecting PABPC1 in Diabetic Retinopathy.	PABPC1 PABPC3	7.34e-06	4	39	2	31847264
Pubmed	RNA-binding proteins in mouse oocytes and embryos: expression of genes encoding Y box, DEAD box RNA helicase, and polyA binding proteins.	PABPC1 PABPC3	7.34e-06	4	39	2	9883581
Pubmed	Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.	PABPC1 PABPC3	7.34e-06	4	39	2	24129315
Pubmed	cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation.	PABPC1 PABPC3	7.34e-06	4	39	2	28910620
Pubmed	ATXN2-CAG42 sequesters PABPC1 into insolubility and induces FBXW8 in cerebellum of old ataxic knock-in mice.	PABPC1 PABPC3	7.34e-06	4	39	2	22956915
Pubmed	Functional cloning of genes that suppress oxidative stress-induced cell death: TCTP prevents hydrogen peroxide-induced cell death.	PABPC1 PABPC3	7.34e-06	4	39	2	19328788
Pubmed	HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage.	PABPC1 PABPC3	1.22e-05	5	39	2	19956697
Pubmed	Interaction of HuDA and PABP at 5'UTR of mouse insulin2 regulates insulin biosynthesis.	PABPC1 PABPC3	1.22e-05	5	39	2	29590218
Pubmed	Poly(A) tail length regulates PABPC1 expression to tune translation in the heart.	PABPC1 PABPC3	1.22e-05	5	39	2	28653618
Pubmed	Embryonic Poly(A)-Binding Protein (EPAB) Is Required for Granulosa Cell EGF Signaling and Cumulus Expansion in Female Mice.	PABPC1 PABPC3	1.22e-05	5	39	2	26492470
Pubmed	Isolation of cDNAs from a mouse astroglial cell line by a subtracted cDNA library.	PABPC1 PABPC3	1.22e-05	5	39	2	1701491
Pubmed	AKAP3 synthesis is mediated by RNA binding proteins and PKA signaling during mouse spermiogenesis.	PABPC1 PABPC3	1.22e-05	5	39	2	24648398
Pubmed	MKRN3-mediated ubiquitination of Poly(A)-binding proteins modulates the stability and translation of GNRH1 mRNA in mammalian puberty.	PABPC1 PABPC3	1.22e-05	5	39	2	33744966
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	PRPF38B SEC31A SIX4 TCF20 CDK12 PABPC3	1.35e-05	472	39	6	38943005
Pubmed	A human MAP kinase interactome.	NAV2 WWTR1 SEC31A TCF20 CSN1S1 PYGO1	1.59e-05	486	39	6	20936779
Pubmed	Disruption of mouse poly(A) polymerase mGLD-2 does not alter polyadenylation status in oocytes and somatic cells.	PABPC1 PABPC3	1.83e-05	6	39	2	17927953
Pubmed	Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation.	IL17A STAT5B	1.83e-05	6	39	2	17363300
Pubmed	Translation of insulin granule proteins are regulated by PDI and PABP.	PABPC1 PABPC3	1.83e-05	6	39	2	32248978
Pubmed	Sensitivity and resistance to regulation by IL-4 during Th17 maturation.	IL17A STAT5B	1.83e-05	6	39	2	21949021
Pubmed	The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein.	PABPC1 PABPC3	1.83e-05	6	39	2	10358005
Pubmed	Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway.	IL17A STAT5B	1.83e-05	6	39	2	17951529
Pubmed	Embryonic poly(A)-binding protein is differently expressed and interacts with the messenger RNAs in the mouse oocytes and early embryos.	PABPC1 PABPC3	1.83e-05	6	39	2	30302808
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PAXIP1 DOCK2 SMARCA4 TRIM33 PRPF38B TAF4 TCF20 PABPC1	2.56e-05	1103	39	8	34189442
Pubmed	E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer.	PABPC1 PABPC3	2.56e-05	7	39	2	34143182
Pubmed	Genetic imbalances in preleukemic thymuses.	PABPC1 PABPC3	2.56e-05	7	39	2	11322760
Pubmed	Chromosomal localization of three human poly(A)-binding protein genes and four related pseudogenes.	PABPC1 PABPC3	2.56e-05	7	39	2	10543404
Pubmed	NMD abnormalities during brain development in the Fmr1-knockout mouse model of fragile X syndrome.	PABPC1 PABPC3	2.56e-05	7	39	2	34784943
Pubmed	Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse.	PABPC1 PABPC3	3.42e-05	8	39	2	21262862
Pubmed	The induction and function of the anti-inflammatory fate of TH17 cells.	TRIM33 IL17A	3.42e-05	8	39	2	32620760
Pubmed	Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.	PABPC1 PABPC3	3.42e-05	8	39	2	22621333
Pubmed	RNA binding protein RBM46 regulates mitotic-to-meiotic transition in spermatogenesis.	PABPC1 PABPC3	4.39e-05	9	39	2	36001654
Pubmed	Embryonic poly(A)-binding protein is required at the preantral stage of mouse folliculogenesis for oocyte-somatic communication.	PABPC1 PABPC3	4.39e-05	9	39	2	28203794
Pubmed	Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase.	PABPC1 PABPC3	4.39e-05	9	39	2	24396066
Pubmed	Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells.	PABPC1 PABPC3	4.39e-05	9	39	2	18625844
Pubmed	Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway.	SMARCA4 TRIM33	5.48e-05	10	39	2	16751102
Pubmed	The RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulator.	PABPC1 PABPC3	5.48e-05	10	39	2	21984414
Pubmed	Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis.	PABPC1 PABPC3	5.48e-05	10	39	2	16798735
Pubmed	Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program.	SMARCA4 TRIM33	6.70e-05	11	39	2	18003620
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	PAXIP1 TRIM33 PRPF38B TCF20 CDK12	7.81e-05	396	39	5	26687479
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	PAXIP1 SMARCA4 TRIM33 SIX4 TCF20	8.00e-05	398	39	5	35016035
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SMARCA4 TRIM33 TAF4 TCF20 PABPC1 CDK12 PABPC3	8.17e-05	954	39	7	36373674
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SMARCA4 SEC31A TAF4 CTNND2 TCF20 PABPC1 PABPC3	8.66e-05	963	39	7	28671696
Pubmed	The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing.	PABPC1 PABPC3	9.48e-05	13	39	2	17218272
Pubmed	Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.	PABPC1 PABPC3	1.11e-04	14	39	2	19716330
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	SMARCA4 TRIM33 RNF213 PRPF38B TAF4 TCF20 CDK12	1.19e-04	1014	39	7	32416067
Pubmed	Uncovering a mammalian neural-specific poly(A) binding protein with unique properties.	PABPC1 PABPC3	1.27e-04	15	39	2	37704377
Pubmed	Developmental diversification of cortical inhibitory interneurons.	CITED2 WWTR1 LHX8	1.48e-04	91	39	3	29513653
Pubmed	IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells.	IL17A STAT5B	1.65e-04	17	39	2	19666510
Pubmed	JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse.	PABPC1 PABPC3	1.65e-04	17	39	2	26627310
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	PAXIP1 SMARCA4 PRPF38B CDK12	1.79e-04	251	39	4	31076518
Pubmed	TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.	SMARCA4 TRIM33	1.85e-04	18	39	2	28068325
Pubmed	Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SEC31A NFAT5 CDK12	1.96e-04	100	39	3	10048485
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SHISA9 EVC RNF213 PRPF38B TAF4 NFAT5 STAT5B AFF3	2.08e-04	1489	39	8	28611215
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	TRIM33 PRPF38B TAF4 SIX4 CTNND2 ACAD11 BMP2K CDK12	2.16e-04	1497	39	8	31527615
Pubmed	The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.	PRPF38B PABPC1 CDK12	2.20e-04	104	39	3	31365120
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	PAXIP1 SMARCA4 TRIM33 TCF20	2.29e-04	268	39	4	33640491
Pubmed	A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.	PABPC1 PABPC3	2.54e-04	21	39	2	19345177
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	CITED2 SIX4 LHX8 TCF20 NFAT5 STAT5B	2.62e-04	808	39	6	20412781
Pubmed	Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes.	SEC31A PABPC1	3.05e-04	23	39	2	20696395
Pubmed	Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation.	SMARCA4 WWTR1	3.33e-04	24	39	2	37543677
Pubmed	Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R.	PABPC1 PABPC3	3.33e-04	24	39	2	25157170
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SMARCA4 WWTR1 TAF4 TCF20 CDK12	3.56e-04	549	39	5	38280479
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	NAV2 RNF213 SEC31A CLCA2 CDK12	3.65e-04	552	39	5	10737800
Pubmed	TERRA transcripts are bound by a complex array of RNA-binding proteins.	PABPC1 PABPC3	4.55e-04	28	39	2	20975687
Pubmed	Specification of jaw identity by the Hand2 transcription factor.	SIX4 LHX8	4.55e-04	28	39	2	27329940
Interaction	SOX7 interactions	PAXIP1 SMARCA4 TRIM33 TCF20	1.69e-05	82	38	4	int:SOX7
Interaction	SP7 interactions	PAXIP1 SMARCA4 TRIM33 SIX4 TCF20 PYGO1	2.06e-05	304	38	6	int:SP7
Cytoband	Ensembl 112 genes in cytogenetic band chr3q22	ACAD11 RYK ASTE1	2.27e-04	135	40	3	chr3q22
Cytoband	3q22.1	ACAD11 ASTE1	6.23e-04	42	40	2	3q22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr4q21	SEC31A BMP2K	6.05e-03	133	40	2	chr4q21
GeneFamily	PHD finger proteins	TRIM33 PYGO1	5.79e-03	90	23	2	88
GeneFamily	RNA binding motif containing	PABPC1 PABPC3	2.97e-02	213	23	2	725
Coexpression	GROSS_HYPOXIA_VIA_HIF1A_ONLY	CITED2 PABPC1 PABPC3	3.35e-07	10	38	3	MM1122
Coexpression	GSE13887_ACT_CD4_VS_NO_TREATED_CD4_TCELL_UP	NAV2 WWTR1 SIX4 LHX8	3.63e-05	129	38	4	M481
Coexpression	GARY_CD5_TARGETS_DN	CITED2 NAV2 PRPF38B BMP2K CDK12 AFF3	3.79e-05	440	38	6	M13893
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	PAXIP1 CITED2 TRIM33 PRPF38B SEC31A TAF4 BMP2K NFAT5 CDK12	4.63e-05	1215	38	9	M41122
CoexpressionAtlas	DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_1000	PAXIP1 CITED2 TAF4 SIX4 NFAT5 PABPC1 CDK12 RYK MDM1 PYGO1	1.01e-06	779	39	10	gudmap_developingKidney_e15.5_Cap mesenchyme_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000	CITED2 DOCK2 NAV2 RNF213 CLCA2 BMP2K NFAT5 AFF3	4.94e-05	740	39	8	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000	CITED2 SIX4 NFAT5 PABPC1 CDK12 RYK	6.16e-05	379	39	6	gudmap_developingKidney_e15.5_1000_k3
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000	CITED2 DOCK2 NAV2 RNF213 WWTR1 NFAT5 SCAMP5 AFF3	8.77e-05	803	39	8	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_1000
CoexpressionAtlas	dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000	CITED2 DOCK2 NAV2 RNF213 CLCA2 BMP2K NFAT5 AFF3	8.84e-05	804	39	8	gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000	SIX4 LHX8 CTNND2 CLCA2 NFAT5 CDK12 STAT5B PYGO1	9.00e-05	806	39	8	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_500	SIX4 LHX8 CLCA2 NFAT5 CDK12 PYGO1	9.13e-05	407	39	6	gudmap_developingLowerUrinaryTract_e14.5_ urethra_500
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_1000	CITED2 NAV2 RNF213 WWTR1 AFF3	1.07e-04	259	39	5	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k1_1000
Disease	blood osmolality measurement	NAV2 NFAT5 ABCA12	6.26e-05	58	39	3	EFO_0007967
Disease	ventricular septal defect (is_implicated_in)	CITED2 EVC	1.53e-04	14	39	2	DOID:1657 (is_implicated_in)
Disease	Muscular Atrophy	CITED2 WWTR1	1.77e-04	15	39	2	C0026846
Disease	Neurogenic Muscular Atrophy	CITED2 WWTR1	1.77e-04	15	39	2	C0270948
Disease	clinical and behavioural ideal cardiovascular health	SMARCA4 NFAT5	4.23e-04	23	39	2	EFO_0007654
Disease	triacylglycerol 48:0 measurement	CTNND2 LINC02876	5.42e-04	26	39	2	EFO_0010403
Disease	gastric adenocarcinoma (is_marker_for)	CDK12 STAT5B	6.30e-04	28	39	2	DOID:3717 (is_marker_for)
Disease	Neoplasm of uncertain or unknown behavior of ovary	SMARCA4 CDK12	6.76e-04	29	39	2	C0496920
Disease	Ovarian Carcinoma	SMARCA4 CDK12	7.23e-04	30	39	2	C0029925
Disease	coronary aneurysm	DOCK2 NAV2	9.85e-04	35	39	2	EFO_1000881
Disease	autism spectrum disorder (implicated_via_orthology)	CTNND2 TCF20 SCAMP5	1.07e-03	152	39	3	DOID:0060041 (implicated_via_orthology)
Disease	colitis (biomarker_via_orthology)	SI IL17A	1.42e-03	42	39	2	DOID:0060180 (biomarker_via_orthology)
Disease	Acute Promyelocytic Leukemia	IL17A STAT5B	1.70e-03	46	39	2	C0023487
Disease	cannabis dependence measurement	CTNND2 AFF3	1.85e-03	48	39	2	EFO_0008457
Disease	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	SMARCA4 STAT5B	2.25e-03	53	39	2	C1961099
Disease	interleukin 1 receptor antagonist measurement	LILRA2 TCF20	2.25e-03	53	39	2	EFO_0004754

Protein segments in the cluster

Peptide	Gene	Start	Entry
NHCNMNINSVAIPIN	AFF3	856	P51826
HSNPEMQQQLEALNQ	CDK12	1141	Q9NYV4
NSFHLLNQAIPMLQN	ABCA12	851	Q86UK0
QQAFFQQQMLAQHQP	BMP2K	541	Q9NSY1
QQQMLAQHQPSQQQA	BMP2K	546	Q9NSY1
IQMLQHQFPSVQSNA	CTNND2	556	Q9UQB3
QVENMQQPNAHRISQ	ASTE1	356	Q2TB18
QYQAAAHQDIPAMQQ	ACAD11	186	Q709F0
QQHLNAQPQVTMQQP	PABPC1	521	P11940
HQAQQNQAEFRMGPV	LILRA2	371	Q8N149
PETHMLQQQQQAQQQ	PAXIP1	396	Q6ZW49
MNENSHVQVPFQQLN	CSN1S1	126	P47710
ARMNNLQLPQHEAFN	MDM1	661	Q8TC05
NSQNNLPQIMAKHQN	LCA5L	191	O95447
QLQVMQAQFAQDNNP	LHX8	236	Q68G74
MVNLNIHNRNTNTNP	IL17A	46	Q16552
NPMANQEQQNQSIFH	NFAT5	1296	O94916
QQHRNAQPQVTMQQL	PABPC3	516	Q9H361
QVMQTGQQHPQTHRQ	DOCK2	1261	Q92608
NHESPVNQLGNMQNM	LINC02876	31	F2Z3M2
FPVHQQMRLHAQQQQ	EVC	866	P57679
KNPHVQQAAQNAAMG	SCAMP5	196	Q8TAC9
ANNPQAISQQDLVHM	RYK	431	P34925
QMQAANNLNQENSRP	C18orf63	496	Q68DL7
YNNALSQNVNMPNQH	PYGO1	161	Q9Y3Y4
QALAQMQAQAHAQPQ	TAF4	471	O00268
QQHPRQAAPQMLQQQ	TRIM33	551	Q9UPN9
QQHQQQQGMSDHDSP	TMCC2	106	O75069
QPAPHQQSKAQAEMQ	NAV2	241	Q8IVL1
HQQFQPLHRMQQTNV	PPP1R32	291	Q7Z5V6
PFNQNQLHQLRAQIM	SMARCA4	171	P51532
LMPVNQNAQVNANLS	SIX4	581	Q9UIU6
PINNLHATQMNNAVP	SHISA9	226	B4DS77
QAQQLQGEALHQMQA	STAT5B	6	P51692
RVAENNQPMNAHSNF	SI	891	P14410
QQQPQHAFNALMGEH	CITED2	41	Q99967
STHNQEAPNLQNQMC	CLCA2	256	Q9UQC9
QNHMNLSENASNNVP	RNF213	3696	Q63HN8
NSQPQHQAAAAAAQQ	PRPF38B	11	Q5VTL8
QQPQQQQHPSQHVMQ	TCF20	316	Q9UGU0
RMPSHQGAEQQQQQH	SEC31A	411	O94979
QPNLVMNHQHQQQMA	WWTR1	186	Q9GZV5