Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstretch-activated, monoatomic cation-selective, calcium channel activity

NALF1 NALF2

3.03e-053642GO:0015275
GeneOntologyMolecularFunctioncalcium channel activity

TRPM6 NALF1 GRIN2B NALF2 RYR2

5.85e-05129645GO:0005262
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TRPM6 KCNH8 SLC4A8 NALF1 GRIN2B SLC4A4 NALF2 RYR2

1.15e-04465648GO:0046873
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TRPM6 NALF1 GRIN2B NALF2 RYR2

1.23e-04151645GO:0015085
GeneOntologyMolecularFunctionsodium:bicarbonate symporter activity

SLC4A8 SLC4A4

1.50e-046642GO:0008510
GeneOntologyMolecularFunctionmechanosensitive monoatomic cation channel activity

NALF1 NALF2

2.10e-047642GO:0140135
GeneOntologyMolecularFunctionATP-dependent protein folding chaperone

TCP1 HSPH1 HSPA4

2.85e-0440643GO:0140662
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC4A8 SLC4A4

7.71e-0413642GO:0140410
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TRPM6 KCNH8 NALF1 GRIN2B NALF2 RYR2

7.97e-04343646GO:0005261
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

TRPM6 KCNH8 SLC4A8 NALF1 GRIN2B SLC4A4 NALF2 RYR2

8.50e-04627648GO:0022890
GeneOntologyMolecularFunctionadenyl-nucleotide exchange factor activity

HSPH1 HSPA4

1.03e-0315642GO:0000774
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

TRPM6 KCNH8 SLC4A8 NALF1 GRIN2B SLC4A4 NALF2 RYR2

1.23e-03664648GO:0008324
GeneOntologyMolecularFunctionmechanosensitive monoatomic ion channel activity

NALF1 NALF2

1.50e-0318642GO:0008381
GeneOntologyMolecularFunctionprotein folding chaperone

TCP1 HSPH1 HSPA4

1.66e-0373643GO:0044183
GeneOntologyMolecularFunctionnucleoside diphosphate kinase activity

AK9 NME9

2.04e-0321642GO:0004550
GeneOntologyCellularComponentpericentriolar material

NEK1 TCP1 CEP192

8.49e-0528643GO:0000242
GeneOntologyCellularComponentsarcoplasmic reticulum lumen

CALU CASQ1

3.28e-049642GO:0033018
DomainFAM155

NALF1 NALF2

1.12e-052632IPR029604
DomainTPR

CTR9 TTC21A GPSM2 CABIN1 PPID

7.42e-05129635SM00028
DomainTPR_repeat

CTR9 TTC21A GPSM2 CABIN1 PPID

8.57e-05133635IPR019734
DomainNa/HCO3_transpt

SLC4A8 SLC4A4

1.11e-045632IPR003024
DomainTPR-contain_dom

CTR9 TTC21A GPSM2 CABIN1 PPID

1.51e-04150635IPR013026
DomainTPR_REGION

CTR9 TTC21A GPSM2 CABIN1 PPID

2.35e-04165635PS50293
DomainTPR

CTR9 TTC21A GPSM2 CABIN1 PPID

2.35e-04165635PS50005
DomainTPR_1

CTR9 TTC21A GPSM2 PPID

2.42e-0490634PF00515
DomainTPR_1

CTR9 TTC21A GPSM2 PPID

2.42e-0490634IPR001440
DomainBand3_cytoplasmic_dom

SLC4A8 SLC4A4

3.97e-049632IPR013769
DomainBand_3_cyto

SLC4A8 SLC4A4

3.97e-049632PF07565
Domain-

SLC4A8 SLC4A4

3.97e-0496323.40.1100.10
DomainPept_M24

PA2G4 PEPD

3.97e-049632IPR000994
DomainPeptidase_M24

PA2G4 PEPD

3.97e-049632PF00557
Domain-

PA2G4 PEPD

3.97e-0496323.90.230.10
DomainHCO3_cotransp

SLC4A8 SLC4A4

4.95e-0410632PF00955
DomainHCO3_transpt_C

SLC4A8 SLC4A4

4.95e-0410632IPR011531
DomainPTrfase/Anion_transptr

SLC4A8 SLC4A4

4.95e-0410632IPR016152
DomainHCO3_transpt_euk

SLC4A8 SLC4A4

4.95e-0410632IPR003020
DomainTPR_7

GPSM2 PPID

4.95e-0410632PF13176
Domain-

CTR9 TTC21A GPSM2 CABIN1 PPID

6.65e-042076351.25.40.10
Domain-

HSPH1 HSPA4

7.23e-04126322.60.34.10
DomainHSP70_peptide-bd

HSPH1 HSPA4

7.23e-0412632IPR029047
DomainTPR_8

CTR9 TTC21A GPSM2

7.60e-0453633PF13181
Domain-

HSPH1 HSPA4

8.53e-04136321.20.1270.10
DomainHeat_shock_70_CS

HSPH1 HSPA4

8.53e-0413632IPR018181
DomainHSP70_C

HSPH1 HSPA4

8.53e-0413632IPR029048
DomainTPR-like_helical_dom

CTR9 TTC21A GPSM2 CABIN1 PPID

1.13e-03233635IPR011990
DomainHSP70

HSPH1 HSPA4

1.30e-0316632PF00012
DomainHSP70_2

HSPH1 HSPA4

1.47e-0317632PS00329
DomainHSP70_3

HSPH1 HSPA4

1.47e-0317632PS01036
DomainHSP70_1

HSPH1 HSPA4

1.47e-0317632PS00297
DomainHsp_70_fam

HSPH1 HSPA4

1.65e-0318632IPR013126
DomainEF-hand_8

CALU RYR2

5.86e-0334632PF13833
DomainIon_trans_dom

TRPM6 KCNH8 RYR2

6.74e-03114633IPR005821
DomainIon_trans

TRPM6 KCNH8 RYR2

6.74e-03114633PF00520
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

NPM1 PALD1 NEK1 NAMPT TCP1 FAM50A PA2G4 ARID2 HSPH1 PEPD YTHDC2 HSPA4

1.19e-07934641233916271
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

NPM1 MIA3 NAMPT SLC4A8 CAMKV GRAMD1A ADGRB3 GRIN2B SLC4A4 PTEN CXADR RYR2

9.80e-071139641236417873
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

NPM1 MIA3 NOP14 PDE7A PA2G4 CALU CTR9 GRAMD1A HSPH1 CEP192 PIBF1 HSPA4 CXADR

2.60e-061487641333957083
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

NPM1 MIA3 TCP1 FAM50A PA2G4 HSPH1 ADGRB3 HSPA4 ERLIN1 DYNC1LI2

3.21e-06847641035235311
Pubmed

Formation of molecular complexes by N-methyl-D-aspartate receptor subunit NR2B and ryanodine receptor 2 in neonatal rat myocard.

GRIN2B RYR2

3.33e-06264215010472
Pubmed

TRIM37 interacts with PTEN to promote the growth of human T-cell acute lymphocytic leukemia cells through regulating PI3K/AKT pathway.

PTEN TRIM37

3.33e-06264236923153
Pubmed

Ebp1 association with nucleophosmin/B23 is essential for regulating cell proliferation and suppressing apoptosis.

NPM1 PA2G4

3.33e-06264217951246
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PDE7A SATB1 KLHL7 CTR9 HSPH1 ADGRB3 GPSM2 GRIN2B CABIN1 TRIM37 DOP1B SOS1

3.42e-061285641235914814
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

MIA3 TCP1 KLHL7 HSPH1 CEP192 PIBF1 PPID TRIM37 ERLIN1 DYNC1LI2

3.42e-06853641028718761
Pubmed

Proteomic analysis of the NOS2 interactome in human airway epithelial cells.

NPM1 TCP1 CALU HSPH1 HSPA4

5.78e-0613864523438482
Pubmed

Hsp110 is a bona fide chaperone using ATP to unfold stable misfolded polypeptides and reciprocally collaborate with Hsp70 to solubilize protein aggregates.

HSPH1 HSPA4

9.99e-06364223737532
Pubmed

Nucleophosmin/B26 regulates PTEN through interaction with HAUSP in acute myeloid leukemia.

NPM1 PTEN

9.99e-06364223183427
Pubmed

SATB1 Chromatin Loops Regulate Megakaryocyte/Erythroid Progenitor Expansion by Facilitating HSP70 and GATA1 Induction.

SATB1 HSPA4

9.99e-06364236987811
Pubmed

Prevalence and pathogenesis of Barrett's esophagus in Luoyang, China.

HSPH1 HSPA4

9.99e-06364222901192
Pubmed

An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes.

NEK1 PIBF1

9.99e-06364226167768
Pubmed

KLHL7 promotes TUT1 ubiquitination associated with nucleolar integrity: Implications for retinitis pigmentosa.

NPM1 KLHL7

9.99e-06364229032201
Pubmed

KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis.

KMT2C PTEN

9.99e-06364235354467
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

PALD1 NAMPT TCP1 PA2G4 CALU PLEKHG3 GRAMD1A HSPH1 YTHDC2 CABIN1 HSPA4 ERLIN1

1.08e-051440641230833792
Pubmed

Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

TCP1 HSPA4 ERLIN1

1.68e-052764321343306
Pubmed

Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity.

NPM1 CEP192 PIBF1

1.68e-052764335709258
Pubmed

LGN loss randomizes spindle orientation and accelerates tumorigenesis in PTEN-deficient epidermis.

GPSM2 PTEN

2.00e-05464237991903
Pubmed

Development and characterization of NEX- Pten, a novel forebrain excitatory neuron-specific knockout mouse.

GRIN2B PTEN

2.00e-05464222572802
Pubmed

Histone deacetylase inhibitors prevent the degradation and restore the activity of glucocerebrosidase in Gaucher disease.

TCP1 HSPA4

2.00e-05464222160715
Pubmed

Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase.

GRIN2B PTEN

2.00e-05464210748157
Pubmed

C-terminal domain of p42 Ebp1 is essential for down regulation of p85 subunit of PI3K, inhibiting tumor growth.

PA2G4 HSPA4

2.00e-05464227464702
Pubmed

Ribosomal stress induces processing of Mybbp1a and its translocation from the nucleolus to the nucleoplasm.

NPM1 PA2G4

2.00e-05464218173745
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MIA3 NOP14 TCP1 CALU CTR9 GRAMD1A CEP192 PIBF1 PTEN CXADR

2.06e-051049641027880917
Pubmed

TRIM37 Mediates Chemoresistance and Maintenance of Stemness in Pancreatic Cancer Cells via Ubiquitination of PTEN and Activation of the AKT-GSK-3β-β-Catenin Signaling Pathway.

NPM1 TCP1 PA2G4 PTEN TRIM37 ERLIN1

2.12e-0530564633194618
Pubmed

Identification and characterization of a novel human PP1 phosphatase complex.

KMT2C TCP1 HSPA4

2.57e-053164320516061
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

PALD1 NEK1 KLHL7 PA2G4 CTR9 TTC21A PIBF1 USH1C PPID ERLIN1 DYNC1LI2

2.66e-051321641127173435
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TRPM6 KMT2C MIA3 PA2G4 CTR9 HSPH1 CEP192 TRIM37 ERLIN1 DYNC1LI2

2.73e-051084641011544199
Pubmed

Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.

TCP1 CALU HSPH1 ERLIN1 RYR2

3.07e-0519564517110338
Pubmed

PTENα Modulates CaMKII Signaling and Controls Contextual Fear Memory and Spatial Learning.

GRIN2B PTEN

3.32e-05564228636948
Pubmed

Proteostasis modulators prolong missense VHL protein activity and halt tumor progression.

TCP1 HSPA4

3.32e-05564223318261
Pubmed

Chromosome mapping of five human cardiac and skeletal muscle sarcoplasmic reticulum protein genes.

CASQ1 RYR2

3.32e-0556428406504
Pubmed

Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3.

NPM1 TCP1 PA2G4 CABIN1 PPID HSPA4

3.40e-0533264630595499
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

NPM1 NAMPT TCP1 FAM50A PA2G4 CALU HSPH1 PPID HSPA4 ERLIN1 PPL

3.64e-051367641132687490
Pubmed

CHFR regulates chemoresistance in triple-negative breast cancer through destabilizing ZEB1.

NPM1 TCP1 HSPH1 HSPA4

3.72e-0510164434462429
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

NPM1 KMT2C TCP1 YTHDC2 PPL

4.17e-0520864533230847
Pubmed

P42 Ebp1 regulates the proteasomal degradation of the p85 regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70/CHIP.

PA2G4 HSPA4

4.98e-05664224651434
Pubmed

GINS1 promotes the proliferation and migration of glioma cells through USP15-mediated deubiquitination of TOP2A.

NPM1 PA2G4

4.98e-05664236065190
Pubmed

WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.

TCP1 HSPA4

4.98e-05664215967112
Pubmed

PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation.

TCP1 HSPH1 YTHDC2 PTEN HSPA4

5.10e-0521764531685992
Pubmed

The tumour suppressor PTEN mediates a negative regulation of the E3 ubiquitin-protein ligase Nedd4.

NPM1 TCP1 PTEN HSPA4

5.20e-0511064418307411
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TRPM6 NPM1 NAMPT TCP1 PA2G4 CALU CTR9 HSPH1 PEPD YTHDC2 HSPA4

5.30e-051425641130948266
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

NPM1 NAMPT NOP14 TCP1 PA2G4 HSPH1 HSPA4 ERLIN1

5.43e-0572564827025967
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

TCP1 GLIS2 ZNF112 CABIN1 ERLIN1 CXADR

5.58e-0536364614691545
Pubmed

Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.

NPM1 NOP14 HSPH1 YTHDC2 HSPA4

5.81e-0522364520020773
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

NPM1 NAMPT TCP1 PA2G4 CALU CTR9 HSPH1 PEPD PPID HSPA4 DYNC1LI2

6.39e-051455641122863883
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NPM1 MIA3 SLC4A8 CAMKV KLHL7 ADGRB3 GRIN2B SLC4A4 CABIN1

6.48e-0596364928671696
Pubmed

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.

NEK1 SYTL4 FAM50A HSPH1 YTHDC2 PPID HSPA4

6.56e-0554764737267103
Pubmed

DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC.

NOP14 TCP1 ARID2 HSPH1

6.84e-0511864437105989
Pubmed

Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain.

GRIN2B PTEN

6.96e-05764221664258
Pubmed

A novel HSF1-mediated death pathway that is suppressed by heat shock proteins.

HSPH1 HSPA4

6.96e-05764217024176
Pubmed

USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.

NPM1 NAMPT TCP1 CALU HSPH1 HSPA4 ERLIN1

8.03e-0556564733567341
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

TCP1 PA2G4 CALU HSPH1 CASQ1 HSPA4 DOP1B

8.76e-0557364728330616
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

NPM1 TCP1 SYTL4 CEP192 PPL CXADR RYR2 DYNC1LI2

8.79e-0577764835844135
Pubmed

Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II.

NPM1 NAMPT CALU HSPH1 HSPA4

8.88e-0524464530349055
Pubmed

Quantitative assessment of complex formation of nuclear-receptor accessory proteins.

PPID HSPA4

9.27e-05864210642522
Pubmed

Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.

CASQ1 RYR2

9.27e-05864211784029
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

NPM1 NOP14 TCP1 KLHL7 PA2G4 PLEKHG3 HSPH1 YTHDC2 ERLIN1 PPL

9.42e-051257641036526897
Pubmed

FAM46C and FNDC3A Are Multiple Myeloma Tumor Suppressors That Act in Concert to Impair Clearing of Protein Aggregates and Autophagy.

NPM1 NAMPT PA2G4 CALU HSPH1

9.58e-0524864532963011
Pubmed

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.

NPM1 CAMKV TCP1 HSPH1 GRIN2B HSPA4

9.92e-0540364630562941
Pubmed

APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

NPM1 TCP1

1.19e-04964219188445
Pubmed

Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus.

PPID HSPA4

1.19e-04964215004035
Pubmed

The Krüppel-like zinc finger protein Glis2 functions as a negative modulator of the Wnt/beta-catenin signaling pathway.

GLIS2 GPSM2

1.19e-04964217289029
Pubmed

Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

TCP1 SYTL4 CALU USH1C PPID

1.26e-0426364512665801
Pubmed

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.

TCP1 CTR9 HSPH1 HSPA4 ERLIN1 CXADR

1.27e-0442264627342126
Pubmed

Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.

TCP1 HSPH1 HSPA4

1.38e-045464331792442
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

NPM1 NAMPT NOP14 TCP1 KLHL7 PA2G4 CTR9 HSPH1 HSPA4 ERLIN1

1.39e-041318641030463901
Pubmed

Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.

NPM1 TCP1 HSPA4 CXADR PCYT1B

1.40e-0426964530442662
Pubmed

A pathway of multi-chaperone interactions common to diverse regulatory proteins: estrogen receptor, Fes tyrosine kinase, heat shock transcription factor Hsf1, and the aryl hydrocarbon receptor.

PPID HSPA4

1.49e-04106429222609
Pubmed

Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS.

HSPH1 HSPA4

1.49e-041064219171884
Pubmed

Identification of novel SHPS-1-associated proteins and their roles in regulation of insulin-like growth factor-dependent responses in vascular smooth muscle cells.

NEK1 HSPA4 SOS1

1.54e-045664319299420
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

NEK1 CEP192 PIBF1 DYNC1LI2

1.56e-0414664421399614
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

NPM1 MIA3 CTR9 ARID2 YTHDC2 HSPA4

1.60e-0444064634244565
Pubmed

RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.

HSPH1 YTHDC2 HSPA4 PPL

1.64e-0414864435676246
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

NPM1 NAMPT NOP14 TCP1 PA2G4 PLEKHG3 CTR9 HSPH1 HSPA4 ERLIN1

1.72e-041353641029467282
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

KMT2C NOP14 TCP1 PA2G4 CALU CTR9 ARID2 HSPH1 HSPA4

1.81e-04110364934189442
Pubmed

INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4.

HSPH1 HSPA4

1.81e-041164231081062
Pubmed

CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.

HSPH1 HSPA4

1.81e-041164236385105
Pubmed

A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.

KMT2C CTR9 ARID2

1.98e-046164320305087
Pubmed

SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.

NPM1 NAMPT PA2G4 CTR9 HSPH1 HSPA4

2.10e-0446364634901782
Pubmed

Cell cycle-dependent palmitoylation of protocadherin 7 by ZDHHC5 promotes successful cytokinesis.

NPM1 TCP1 PA2G4 HSPA4

2.16e-0415964436762613
Pubmed

Characterization of the Cullin7 E3 ubiquitin ligase--heterodimerization of cullin substrate receptors as a novel mechanism to regulate cullin E3 ligase activity.

TCP1 HSPA4

2.17e-041264221946088
Pubmed

Respiratory distress and early neonatal lethality in Hspa4l/Hspa4 double-mutant mice.

HSPH1 HSPA4

2.17e-041264223980576
Pubmed

Heat-shock protein HSPA4 is required for progression of spermatogenesis.

HSPH1 HSPA4

2.17e-041264221487003
Pubmed

Ebp1 sumoylation, regulated by TLS/FUS E3 ligase, is required for its anti-proliferative activity.

NPM1 PA2G4

2.17e-041264219946338
Pubmed

Aerobic glycolysis tunes YAP/TAZ transcriptional activity.

NPM1 PA2G4 HSPH1 HSPA4

2.32e-0416264425796446
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

NAMPT FAM50A ARID2 PEPD PPID DYNC1LI2

2.33e-0447264638943005
Pubmed

A novel LZAP-binding protein, NLBP, inhibits cell invasion.

NPM1 HSPA4

2.57e-041364220164180
Pubmed

Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis.

KMT2C HSPA4

2.57e-041364221502505
Pubmed

Human transcription factor protein interaction networks.

KMT2C NOP14 SATB1 TCP1 CALU ARID2 HSPH1 CEP192 CABIN1 HSPA4

2.66e-041429641035140242
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NEK1 SLC4A8 PLEKHG3 ARID2 GRAMD1A HSPH1

2.94e-0449364615368895
Pubmed

Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor.

NPM1 PA2G4

2.99e-041464219037095
Pubmed

The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.

KMT2C CTR9

2.99e-041464219136632
Pubmed

MED12 regulates a transcriptional network of calcium-handling genes in the heart.

CASQ1 RYR2

2.99e-041464228724790
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

NPM1 PALD1 TCP1 HSPH1 YTHDC2 HSPA4 ERLIN1

3.20e-0470864739231216
Pubmed

Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells.

SATB1 TCP1 HSPH1 CABIN1

3.32e-0417864427637333
Pubmed

RNA Directed Modulation of Phenotypic Plasticity in Human Cells.

NPM1 PA2G4

3.45e-041564227082860
InteractionMET interactions

CAMKV CALU GLIS2 GRIN2B SLC4A4 PTEN HSPA4 CXADR SOS1

2.43e-07290629int:MET
InteractionAPEX2 interactions

GRAMD1A HSPA4 TRIM37 ERLIN1

7.55e-0641624int:APEX2
InteractionCNTNAP2 interactions

NPM1 NAMPT SLC4A8 CTR9 SLC4A4 CXADR

9.03e-06158626int:CNTNAP2
InteractionTRIM37 interactions

NPM1 ZNF776 TCP1 SYTL4 PA2G4 CEP192 PIBF1 PTEN TRIM37 ERLIN1

2.06e-056306210int:TRIM37
InteractionLRRC4C interactions

SLC4A8 ADGRB3 GRIN2B SLC4A4 CXADR

2.23e-05110625int:LRRC4C
InteractionNAA40 interactions

NPM1 PALD1 NEK1 NAMPT TCP1 FAM50A PA2G4 ARID2 HSPH1 PEPD YTHDC2 HSPA4

3.64e-059786212int:NAA40
CytobandEnsembl 112 genes in cytogenetic band chr3p24

KCNH8 SATB1 DAZL

5.42e-04113643chr3p24
Cytoband3p24.3

KCNH8 DAZL

6.57e-04276423p24.3
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

CTR9 TTC21A GPSM2 PPID

1.73e-04115444769
GeneFamilyHeat shock 70kDa proteins

HSPH1 HSPA4

7.69e-0417442583
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

HSPH1 AOX1 PEPD SLC4A4 USH1C HSPA4

2.92e-07187646acd305475f3609800af0d7bc68d83ef41228080b
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal-CFuPNs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

SATB1 ABCA6 CAMKV ADGRB3 GRIN2B CXADR

3.73e-07195646574354ef4bcefeb9856b65d19bb92e2cffe5dc7a
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

SATB1 AOX1 SLC4A4 USH1C HSPA4

5.47e-0617664536f77d878a53b30465b0dea8333a3865dba75613
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE7A AOX1 PEPD SLC4A4 USH1C

5.94e-0617964578fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NALF1 ABCA6 ADGRB3 RYR2 SULT1E1

6.27e-061816459ede19228ba5c0668a9c06c915510b95585216ef
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE7A AOX1 PEPD SLC4A4 USH1C

7.35e-06187645dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE7A AOX1 PEPD SLC4A4 USH1C

7.35e-06187645f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell(02)_Cycling_Basal_(regeneration)-(1)_24hpi|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint

NPM1 PA2G4 HSPH1 PPID PPL

7.74e-06189645311f3aed469be3c8ff913dcc5a2442daa8446d55
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 AOX1 ADGRB3 GPSM2 RYR2

7.74e-061896452a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 AOX1 ADGRB3 GPSM2 RYR2

8.14e-06191645b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NAMPT TCP1 HSPH1 HSPA4 TRIM37

8.35e-061926453f925a80b5e2b0577d573e88598a2984a5f6a789
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NPM1 NALF1 ADGRB3 SLC4A4 SULT1E1

8.78e-0619464528c5482da199bcee9e85258a88af453d9fdbd56a
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NALF1 ADGRB3 GPSM2 RYR2 SULT1E1

8.78e-0619464535f132cc38ac133be01834ed0946188aa0757eb4
ToppCellE12.5|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NPM1 TCP1 PA2G4 HSPH1 PPID

8.78e-061946454b335e4da58de1cd94194dc4208ce83854e5e50a
ToppCellIPF-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

NAMPT NALF1 ADGRB3 USH1C SULT1E1

8.78e-06194645e8a9005963704286bcc50785bda8d7d63ec001b1
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NPM1 NALF1 ADGRB3 SLC4A4 SULT1E1

9.00e-06195645c5d2d9f12fd893331c9de261af30607d845d4f6a
ToppCellCV-Severe-2|CV / Virus stimulation, Condition and Cluster

NPM1 NAMPT NOP14 TCP1 PA2G4

9.00e-061956451cde7f6e6c9c610bacc79014519447112c27dd9d
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NALF1 ABCA6 ADGRB3 SLC4A4 SULT1E1

9.46e-0619764573a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLC4A8 TTC21A AK9 NME9 DRC3

9.93e-0619964515f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Proliferative_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NPM1 SYTL4 GPSM2 NALF2 SULT1E1

9.93e-06199645b65fbfed4a9938820cf900afd350b4ecb789b7b3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

NOP14 ZNF658 PLEKHG3 TTC21A NME9

1.02e-052006456b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

ABCA6 SYTL4 AOX1 GPSM2 RYR2

1.02e-05200645a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell367C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PALD1 SLC4A8 ZNF620 CXADR

1.17e-0597644a1279377bf0ee5662db8b9303f5f1fd418dee6df
ToppCell367C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PALD1 SLC4A8 ZNF620 CXADR

1.17e-059764412cbd03b33e76e5e471bbee2a9c11f27e8b21123
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma-4|TCGA-Cervix / Sample_Type by Project: Shred V9

TTC21A ZNF620 SLC4A4 DRC3

5.22e-05142644369f2e51e0283a4de70e6c7a3b95672c0838f205
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNH8 SLC4A8 CAMKV AK9

1.02e-04169644606aa4ff25380d9470ec116ca86cd20f8b19587a
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNH8 SLC4A8 CAMKV AK9

1.02e-04169644052aae2af5446a0de071d5dda5381b0b9a0ed54d
ToppCelldroplet-Lung-LUNG-30m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 SLC4A4 CXADR DRC3

1.20e-041766445201f003192c033655ba47f0faf8c47a96eae03d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NALF1 ABCA6 AOX1 RYR2

1.22e-041776449ec7f1e64312d26d434b3312b58386715dbad644
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NALF1 ABCA6 AOX1 RYR2

1.22e-04177644016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 SLC4A4 CXADR RYR2

1.25e-0417864476e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 SLC4A4 CXADR RYR2

1.25e-0417864482f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCelldroplet-Lung-30m-Epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 SLC4A4 CXADR RYR2

1.25e-041786445442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 SLC4A4 CXADR RYR2

1.25e-04178644523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCellCOPD-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

NAMPT NALF1 HERC2P3 SULT1E1

1.28e-04179644e816dd846a6918ec143b57a380c3a47ed073b66e
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 GPSM2 RYR2 SULT1E1

1.31e-0418064408ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NALF1 ABCA6 GPSM2 SULT1E1

1.33e-041816449e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCellhealthy_donor-Myeloid-Monocytic-SC_&_Eosinophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

TRPM6 SYTL4 AOX1 ZNF112

1.36e-041826446bd6c32c48fecd6d03ac8a09e405b3b99bdc12ae
ToppCellfacs-Skin-Telogen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SATB1 TCP1 HSPA4 PPL

1.39e-0418364426b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 PALD1 ADGRB3 RYR2

1.39e-04183644dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 PALD1 ADGRB3 RYR2

1.39e-041836444759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NPM1 PALD1 PA2G4 PPID

1.39e-04183644523896bd1a93bdda81a009768baa3a1bdbd108b8
ToppCelldroplet-Lung-LUNG-30m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC21A NME9 DRC3 PCYT1B

1.39e-041836443991830726d05cf19606d540de04093985b7bdeb
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC21A NME9 DRC3 PCYT1B

1.39e-04183644cc844f54c7564bf432b179ca63bc7c4b9b8cfdd9
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PALD1 ABCA6 CAMKV ADGRB3

1.42e-041846441c56378b3888c46258d446b47de4d6282fe74b0d
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

AOX1 PEPD SLC4A4 USH1C

1.42e-04184644dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PALD1 ABCA6 CAMKV ADGRB3

1.42e-04184644a45980306c4e697a2703bed72a7b48fb23d942f4
ToppCelldroplet-Mammary_Gland-nan-3m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPM1 SATB1 GRAMD1A HSPH1

1.45e-0418564402a2cbae9238c6c1e80b9a52a575e3b22f0eebb4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AOX1 PEPD SLC4A4 USH1C

1.48e-041866448287146f0ba415ea04475588117d4668ae00f75c
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAMKV ADGRB3 GRIN2B NALF2

1.48e-04186644bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AOX1 PEPD SLC4A4 USH1C

1.48e-041866445784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AOX1 PEPD SLC4A4 USH1C

1.51e-0418764471eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NALF1 ADGRB3 SLC4A4 SULT1E1

1.51e-04187644a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

AOX1 PEPD SLC4A4 USH1C

1.51e-04187644d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 NALF1 ABCA6 PPL

1.51e-0418764477886f99c229610abd28c4c370d2c7d1536c9782
ToppCell(04)_Pre-ciliated-(3)_72hpi|(04)_Pre-ciliated / shred by cell type and Timepoint

HSPH1 NME9 PPID DRC3

1.54e-04188644f911dc61b008b60aaa2a1e9354085f480a669e2c
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-ELP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NPM1 SATB1 TTC21A AOX1

1.54e-041886440a47de24812c619f6756c9351a413b109128d54f
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

NEK1 TTC21A AK9 DRC3

1.54e-041886448f30535a32968a81a304315a49c0d90a77d36948
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 AOX1 GPSM2 SULT1E1

1.57e-04189644a153b83314cf52808f685296cff8c95af3f4983d
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

ABCA6 AOX1 ADGRB3 RYR2

1.61e-041906443a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NAMPT NALF1 ADGRB3 RYR2

1.64e-0419164408720998aa55131d7377c4c67c4c935865bd7d79
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA6 AOX1 ADGRB3 RYR2

1.64e-041916446688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 AOX1 ADGRB3 GPSM2

1.67e-041926446f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ARID2 HSPH1 HSPA4 SOS1

1.67e-04192644916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

NPM1 PDE7A SATB1 HSPH1

1.67e-0419264435557254738844c27ffcd00f3287fbcc0a4d0f3b
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NAMPT ADGRB3 HSPA4 SULT1E1

1.67e-041926446bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 AOX1 GPSM2 RYR2

1.67e-04192644f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA6 AOX1 ADGRB3 RYR2

1.67e-0419264499ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 AOX1 GPSM2 SULT1E1

1.67e-04192644dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-CFuPNs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

SATB1 CAMKV ADGRB3 CXADR

1.67e-04192644a8841ebd879f1c344ab4246fdef77044170f644d
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 AOX1 GPSM2 RYR2

1.67e-041926443d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NAMPT TCP1 HSPH1 HSPA4

1.71e-04193644dbf0fe496254320c894568c31e5f9ce63707d1b5
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA6 AOX1 ADGRB3 RYR2

1.71e-0419364499525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 AOX1 ADGRB3 GPSM2

1.71e-04193644fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

ABCA6 SYTL4 AOX1 ADGRB3

1.71e-04193644dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellbackground-Cholangiocytes|background / Sample and Cell Type and Tumor Cluster (all cells)

KCNH8 NALF1 SLC4A4 USH1C

1.71e-041936449152241073dbe02ac2c11d86bec9b5b529196f6e
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ARID2 HSPH1 HSPA4 SOS1

1.71e-04193644e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

NALF1 ABCA6 ADGRB3 RYR2

1.71e-04193644acad568621ed677031797b8c2e34dafea798d681
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA6 AOX1 ADGRB3 RYR2

1.74e-04194644e93de9428c986b8943fc169258847c650cfab0e5
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NALF1 ABCA6 ADGRB3 RYR2

1.74e-04194644011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NALF1 ABCA6 ADGRB3 SLC4A4

1.74e-04194644b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 AOX1 ADGRB3 GPSM2

1.74e-0419464460622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 AOX1 ADGRB3 GPSM2

1.74e-0419464489b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NPM1 NALF1 ADGRB3 SULT1E1

1.74e-04194644a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAMPT ABCA6 AOX1 GPSM2

1.77e-04195644ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NALF1 ABCA6 ADGRB3 SULT1E1

1.77e-041956441cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 AOX1 ADGRB3 RYR2

1.77e-04195644df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 AOX1 ADGRB3 RYR2

1.77e-041956444243190ad291d56694e2155954dbaa879c9d3844
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Ciliated|Control_saline / Treatment groups by lineage, cell group, cell type

TTC21A AK9 NME9 DRC3

1.77e-0419564460067b5359174f0d1a8b5748bfc0690762e9e740
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

ABCA6 AOX1 ADGRB3 RYR2

1.77e-04195644aa0add081881d349099d12efca5cdee098038d4e
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CALU GPSM2 RYR2 SULT1E1

1.81e-04196644525d6c8a277364e624e7cc586275f8a891436b57
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NPM1 ADGRB3 SLC4A4 SULT1E1

1.81e-04196644dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NALF1 ADGRB3 GRIN2B RYR2

1.81e-04196644676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 PLEKHG3 PPL CXADR

1.81e-0419664422fcfb713f402ebbd43b2822f0fd919cdbfba6e4
ToppCellPCW_07-8.5-Mesenchymal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NPM1 ADGRB3 SLC4A4 SULT1E1

1.81e-041966448e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-41|World / Primary Cells by Cluster

CAMKV TCP1 GRIN2B CXADR

1.81e-04196644dee0984cd63a1a2fdebb4421af48ab566a5b684e
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NPM1 NALF1 ADGRB3 SULT1E1

1.81e-0419664422538376a95fe3afe8639a216a5497087aa94110
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NALF1 ABCA6 ADGRB3 SULT1E1

1.81e-041966441450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA6 AOX1 ADGRB3 RYR2

1.81e-04196644bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA6 AOX1 ADGRB3 RYR2

1.81e-041966447d8505dac15fa59935ccf592afc54b04c4c6554f
Drugp-nitrobenzoyl chloride

SLC4A4 TRIM37

7.54e-062632CID000008502
DrugAlbendazole

TCP1 HSPH1 PPID HSPA4

7.96e-0646634ctd:D015766
DrugTag Peptide

NAMPT HSPH1 AOX1

1.34e-0517633CID005486959
DrugIsoxsuprine hydrochloride [579-56-6]; Down 200; 11.8uM; HL60; HG-U133A

KLHL7 CALU PEPD PPID HSPA4 ERLIN1

1.65e-051956361985_DN
DrugLY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A

CALU CABIN1 NALF2 ERLIN1 DOP1B SOS1

1.75e-051976366935_DN
DrugSulfathiazole [72-14-0]; Down 200; 15.6uM; HL60; HG-U133A

NEK1 MIA3 PIBF1 HSPA4 TRIM37 SOS1

1.80e-051986361963_DN
DiseaseAdenocarcinoma of lung (disorder)

TRPM6 NPM1 NEK1 SATB1 SLC4A4 SOS1

5.76e-06206646C0152013
Diseasefetal alcohol spectrum disorder (biomarker_via_orthology)

GRIN2B PTEN

2.77e-054642DOID:0050696 (biomarker_via_orthology)
DiseaseLong QT Syndrome

PTEN RYR2

2.52e-0411642C0023976
Diseaseretinitis pigmentosa (biomarker_via_orthology)

GRIN2B PTEN

3.56e-0413642DOID:10584 (biomarker_via_orthology)
DiseaseProstatic Neoplasms

KMT2C TCP1 ARID2 AOX1 PTEN PPL SULT1E1

3.70e-04616647C0033578
DiseaseMalignant neoplasm of prostate

KMT2C TCP1 ARID2 AOX1 PTEN PPL SULT1E1

3.70e-04616647C0376358
Diseaseanemia (implicated_via_orthology)

SLC4A8 SLC4A4

4.77e-0415642DOID:2355 (implicated_via_orthology)
Diseasesuperior frontal gyrus volume measurement

PALD1 GRAMD1A

6.93e-0418642EFO_0010329
DiseaseJoubert syndrome 1

PIBF1 TRIM37

9.47e-0421642C4551568
DiseaseLEOPARD Syndrome

PTEN SOS1

1.04e-0322642C0175704
DiseaseNeurodevelopmental Disorders

KMT2C GRIN2B PTEN

1.10e-0393643C1535926
DiseaseIntrahepatic Cholangiocarcinoma

KMT2C PTEN

1.24e-0324642C0345905
DiseaseExtrahepatic Cholangiocarcinoma

KMT2C PTEN

1.24e-0324642C3805278
DiseaseRS-10-hydroxywarfarin measurement

TRPM6 NALF1 KLHL7

1.28e-0398643EFO_0803330
DiseaseTEMPS-A questionnaire

ADGRB3 SLC4A4

1.35e-0325642EFO_0004783
DiseaseCholangiocarcinoma

KMT2C PTEN

1.46e-0326642C0206698
DiseaseSezary Syndrome

KMT2C PTEN

1.57e-0327642C0036920
DiseaseCiliopathies

NEK1 GLIS2 USH1C

1.78e-03110643C4277690
DiseaseChild Development Disorders, Specific

SLC4A4 PTEN

1.81e-0329642C0085997
DiseaseChild Development Deviations

SLC4A4 PTEN

1.81e-0329642C0085996
DiseaseDevelopmental Disabilities

SLC4A4 PTEN

1.94e-0330642C0008073

Protein segments in the cluster

PeptideGeneStartEntry
HKVDFLIENDAEKDY

USH1C

11

Q9Y6N9
EEQLDEEHLESHKKY

AKAP2

251

Q9Y2D5
LAYQFDHFSHEKIKD

ADGRB3

86

O60242
ADYDKTLIFNKIHHE

ERLIN1

111

O75477
HKLEAVKHNFNLEEY

ABCA6

1561

Q8N139
YLEKYEKVHHFGEDD

ARID2

96

Q68CP9
DKVHNDAQSFDYDHD

CALU

36

O43852
DYFHHLERELAKAEK

GRAMD1A

521

Q96CP6
ADKYESALEDLHSKH

AOX1

546

Q06278
DKDYHFKVDNDENEH

NPM1

26

P06748
IHSKEHFKEKYAVDD

PEPD

111

P12955
KEEFQIHDELLKAHY

PALD1

66

Q9ULE6
KDHEKAEFEVHEVYA

PA2G4

211

Q9UQ80
QDYEKAIDYHLKHLA

GPSM2

296

P81274
YKFDFEDDQHKIPCH

KMT2C

4886

Q8NEZ4
FKNKEDQYDHLDAAD

HSPA4

716

P34932
FEINVHEDAKEHEKE

NEK1

736

Q96PY6
QKFIDADVEERHHAY

DOP1B

346

Q9Y3R5
ADFRNKDEKYNHIDE

HSPH1

731

Q92598
EKEHDYRDEHLDFIQ

DYNC1LI2

241

O43237
EFLEKHKIDFVAHDD

PCYT1B

156

Q9Y5K3
DYHQFHEDVKDAQEL

PPL

321

O60437
TEEFFHQGDIEKKYH

PDE7A

381

Q13946
DDFIHQHFTEVYKTD

KLHL7

166

Q8IXQ5
HAQEKYDEFDLVLHK

NALF2

256

O75949
VDHVNDYHVKPEKDA

GLIS2

186

Q9BZE0
RHHEKKSIYNLNEDE

NOP14

111

P78316
LQKHDRFEESAKAYH

CABIN1

46

Q9Y6J0
EDDYENHDKNLFRKI

CAMKV

226

Q8NCB2
DKKFSAHYDAVEAEL

FAM50A

46

Q14320
QAEEKFEDAYEKLHH

AXDND1

941

Q5T1B0
FEDAYEKLHHTLIKN

AXDND1

946

Q5T1B0
EEKYEKEVHHDIRED

CXADR

266

P78310
SEHYKAFEDAAEEFH

CASQ1

191

P31415
AKAEAEHDEHYYNAI

CTR9

481

Q6PD62
QEDEKQKDYSHVRHF

CEP192

751

Q8TEP8
VTQDDYFKDKRVHHF

DAZL

271

Q92904
AEAKHQYSIDELKHQ

DRC3

201

Q9H069
KLEYFINKYAEHSHD

RYR2

2716

Q92736
DDVVRFLDSKHKNHY

PTEN

51

P60484
HVKECHQLAYADEAK

SYTL4

376

Q96C24
EKFLEHPEDYVAHEE

AK9

971

Q5TCS8
EEKIQNEDYHHELSD

TRIM37

501

O94972
EAKEDSLDEEFFHHK

MIA3

681

Q5JRA6
LLDKIKSYYENAEHH

PLEKHG3

716

A1L390
EKFEDENFHYKHDRE

PPID

101

Q08752
ESKDDKHGSYEDAVH

TCP1

536

P17987
QEAKDVYKEHFQDDV

NAMPT

81

P43490
DEIFHDVAYKAKERD

SLC4A8

366

Q2Y0W8
SQIHYSYNEEKDEDH

HERC2P3

76

Q9BVR0
INDKDDTNEYKHAFE

SOS1

501

Q07889
LEEAHELSEDHYKKY

SOS1

901

Q07889
EIDHYCKHSEEIKDN

SIX6OS1

61

Q8N1H7
EHYENAIEYDCKEEH

SATB1

81

Q01826
LHDFEEQCVEKYFHE

TRPM6

1146

Q9BX84
HFTVALNEKFDKHYE

SULT1E1

266

P49888
RDHYKTEYENKLHDE

PIBF1

366

Q8WXW3
ARHHEAYEVKNGEKF

ZNF620

156

Q6ZNG0
YQHKAGEEAFEKLVH

NME9

206

Q86XW9
AEHYLAEKEYDKAVQ

TTC21A

896

Q8NDW8
KAHAEEKSYEHGENA

ZNF658

181

Q5TYW1
DKLEVHRKENYSCHD

ZNF112

221

Q9UJU3
LLKAYHHSFDDEKVD

YTHDC2

591

Q9H6S0
EVFHDIAYKAKDRHD

SLC4A4

351

Q9Y6R1
FGAYEKKLDDDANHH

ZNF776

116

Q68DI1
EYAHKFVEDIQHDLT

KCNH8

656

Q96L42
YDHHAQEKYEEFESV

NALF1

271

B1AL88
DEVAIKDAHEKDDFH

GRIN2B

46

Q13224