Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein serine kinase activity

CDK9 MTOR RPS6KA1 PRKACA PRKACB ALPK3 CDK11A CDK11B

4.33e-05363718GO:0106310
GeneOntologyMolecularFunctioncyclin-dependent protein serine/threonine kinase activity

CDK9 CDK11A CDK11B

1.63e-0430713GO:0004693
GeneOntologyMolecularFunctioncyclin-dependent protein kinase activity

CDK9 CDK11A CDK11B

1.63e-0430713GO:0097472
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

CDK9 MTOR RPS6KA1 PRKACA PRKACB ALPK3 CDK11A CDK11B

1.81e-04446718GO:0004674
GeneOntologyMolecularFunctioncAMP-dependent protein kinase activity

PRKACA PRKACB

2.59e-047712GO:0004691
GeneOntologyMolecularFunctioncyclic nucleotide-dependent protein kinase activity

PRKACA PRKACB

4.42e-049712GO:0004690
GeneOntologyMolecularFunctionAMP-activated protein kinase activity

PRKACA PRKACB

5.51e-0410712GO:0004679
GeneOntologyMolecularFunctionprotein kinase activity

CDK9 MTOR RPS6KA1 PRKACA PRKACB ALPK3 CDK11A CDK11B

1.28e-03600718GO:0004672
GeneOntologyCellularComponentserine/threonine protein kinase complex

CDK9 PRKACA PRKACB CDK11A CDK11B

2.23e-04157735GO:1902554
GeneOntologyCellularComponentprotein kinase complex

CDK9 PRKACA PRKACB CDK11A CDK11B

3.22e-04170735GO:1902911
GeneOntologyCellularComponentcAMP-dependent protein kinase complex

PRKACA PRKACB

5.32e-0410732GO:0005952
DomainARM-like

DNAJC13 MROH1 ARMC3 MTOR MROH2A ANKAR TEX10 WDFY4

7.48e-06270708IPR011989
Domain-

DNAJC13 MROH1 ARMC3 MTOR ANKAR TEX10 WDFY4

1.94e-052227071.25.10.10
DomainARM-type_fold

DNAJC13 MROH1 ARMC3 MTOR MROH2A ANKAR TEX10 WDFY4

3.85e-05339708IPR016024
DomainHEAT_REPEAT

MROH1 MTOR MROH2A TEX10

1.38e-0470704PS50077
DomainGAIN_dom_N

ADGRB3 ADGRL1

7.45e-0411702IPR032471
DomainGAIN

ADGRB3 ADGRL1

7.45e-0411702PF16489
DomainKinase-like_dom

CDK9 MTOR RPS6KA1 PRKACA PRKACB ALPK3 CDK11A CDK11B

9.29e-04542708IPR011009
DomainAGC-kinase_C

RPS6KA1 PRKACA PRKACB

1.21e-0356703IPR000961
DomainAGC_KINASE_CTER

RPS6KA1 PRKACA PRKACB

1.21e-0356703PS51285
DomainS_TK_X

RPS6KA1 PRKACA PRKACB

1.21e-0356703SM00133
DomainHEAT

MROH1 MTOR TEX10

1.34e-0358703IPR000357
DomainRhoGAP

TAGAP ARHGAP25 ARHGAP45

1.63e-0362703SM00324
DomainRhoGAP

TAGAP ARHGAP25 ARHGAP45

1.70e-0363703PF00620
DomainRHOGAP

TAGAP ARHGAP25 ARHGAP45

1.78e-0364703PS50238
DomainRhoGAP_dom

TAGAP ARHGAP25 ARHGAP45

1.78e-0364703IPR000198
Domain-

TAGAP ARHGAP25 ARHGAP45

1.78e-03647031.10.555.10
DomainHEAT_type_2

MROH1 TEX10

1.82e-0317702IPR021133
DomainSer/Thr_kinase_AS

CDK9 RPS6KA1 PRKACA PRKACB CDK11A CDK11B

2.19e-03357706IPR008271
DomainS_TKc

CDK9 RPS6KA1 PRKACA PRKACB CDK11A CDK11B

2.25e-03359706SM00220
DomainPROTEIN_KINASE_ST

CDK9 RPS6KA1 PRKACA PRKACB CDK11A CDK11B

2.35e-03362706PS00108
DomainRCC1

HERC3 HERC1

2.52e-0320702PF00415
DomainRCC1_1

HERC3 HERC1

2.78e-0321702PS00625
DomainRCC1_2

HERC3 HERC1

2.78e-0321702PS00626
DomainRCC1_3

HERC3 HERC1

2.78e-0321702PS50012
DomainPkinase

CDK9 RPS6KA1 PRKACA PRKACB CDK11A CDK11B

3.03e-03381706PF00069
DomainReg_chr_condens

HERC3 HERC1

3.05e-0322702IPR000408
Domain-

HERC3 HERC1

3.05e-03227022.130.10.30
DomainRCC1/BLIP-II

HERC3 HERC1

3.33e-0323702IPR009091
DomainHormR

ADGRB3 ADGRL1

3.93e-0325702SM00008
DomainRho_GTPase_activation_prot

TAGAP ARHGAP25 ARHGAP45

4.41e-0388703IPR008936
DomainHECT

HERC3 HERC1

4.57e-0327702PF00632
DomainHECTc

HERC3 HERC1

4.57e-0327702SM00119
DomainHECT_dom

HERC3 HERC1

4.57e-0327702IPR000569
DomainHECT

HERC3 HERC1

4.57e-0327702PS50237
DomainHRM

ADGRB3 ADGRL1

4.91e-0328702PF02793
DomainFYVE

MTMR3 FGD1

5.27e-0329702PF01363
DomainFYVE

MTMR3 FGD1

5.27e-0329702SM00064
DomainArm

ARMC3 ANKAR

6.00e-0331702PF00514
DomainGPS

ADGRB3 ADGRL1

7.19e-0334702SM00303
DomainZnf_FYVE-rel

MTMR3 FGD1

7.19e-0334702IPR017455
DomainGPCR_2_secretin-like_CS

ADGRB3 ADGRL1

7.19e-0334702IPR017983
DomainPROTEIN_KINASE_ATP

CDK9 RPS6KA1 PRKACA PRKACB CDK11A CDK11B

7.43e-03459706PS00107
PathwayREACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS

RPS6KA1 PRKACA PRKACB

2.61e-0515563MM15103
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS

PRKACA PRKACB

1.54e-045562M26988
PathwayKEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY

PRKACA PRKACB TSHR

2.02e-0429563M47627
PathwayREACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION

PRKACA PRKACB

2.30e-046562MM14628
PathwayPID_INTEGRIN_A4B1_PATHWAY

PRKACA PRKACB JAML

2.98e-0433563M277
PathwayKEGG_MEDICUS_REFERENCE_PKA_HOLOENZYME

PRKACA PRKACB

3.21e-047562M47896
PathwayREACTOME_HDL_ASSEMBLY

PRKACA PRKACB

3.21e-047562MM15560
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

RPS6KA1 PRKACA PRKACB

3.55e-0435563MM15109
PathwayREACTOME_HDL_ASSEMBLY

PRKACA PRKACB

4.27e-048562M27840
PathwayREACTOME_ADAPTIVE_IMMUNE_SYSTEM

ASB18 ASB13 MTOR PRKACA PRKACB HERC3 KIF3C HERC1 JAML FBXO2

4.72e-047195610MM14540
PathwayREACTOME_ROBO_RECEPTORS_BIND_AKAP5

PRKACA PRKACB

5.48e-049562M27877
PathwayKEGG_MEDICUS_REFERENCE_AVP_V2R_PKA_SIGNALING_PATHWAY

PRKACA PRKACB

6.83e-0410562M47648
PathwayREACTOME_SIGNALING_BY_VEGF

MTOR PRKACA PRKACB CYFIP2

7.38e-04103564MM14752
PathwayWP_TRANSLATION_INHIBITORS_IN_CHRONICALLY_ACTIVATED_PDGFRA_CELLS

MTOR RPS6KA1 PRKACA

7.99e-0446563M39805
PathwayREACTOME_SIGNALING_BY_VEGF

MTOR PRKACA PRKACB CYFIP2

8.21e-04106564M27077
PathwayWP_THERMOGENESIS

MTOR RPS6KA1 PRKACA PRKACB

8.81e-04108564M39746
PathwayREACTOME_REGULATION_OF_GLYCOLYSIS_BY_FRUCTOSE_2_6_BISPHOSPHATE_METABOLISM

PRKACA PRKACB

9.97e-0412562M27950
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_ADENYLATE_CYCLASE

PRKACA PRKACB

9.97e-0412562M27363
Pubmed

GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor.

MTOR PRKACA PRKACB

3.54e-08473331112131
Pubmed

Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms.

CDK11A CDK11B

4.35e-0627328195233
Pubmed

Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase.

PRKACA PRKACB

4.35e-0627323023318
Pubmed

Global consequences of activation loop phosphorylation on protein kinase A.

PRKACA PRKACB

4.35e-06273219965870
Pubmed

Protein kinase A translocation and insulin secretion in pancreatic beta-cells: studies with adenylate cyclase toxin from Bordetella pertussis.

PRKACA PRKACB

4.35e-06273212180908
Pubmed

Hermansky-Pudlak syndrome: Five Chinese patients with novel variants in HPS1 and HPS6.

HPS1 HPS6

4.35e-06273233878481
Pubmed

Recurrent Rearrangements in PRKACA and PRKACB in Intraductal Oncocytic Papillary Neoplasms of the Pancreas and Bile Duct.

PRKACA PRKACB

4.35e-06273231678302
Pubmed

Alterations in the PITSLRE protein kinase gene complex on chromosome 1p36 in childhood neuroblastoma.

CDK11A CDK11B

4.35e-0627327920654
Pubmed

Regulated expression of a cell division control-related protein kinase during development.

CDK11A CDK11B

4.35e-0627322069872
Pubmed

A cyclin-dependent kinase homologue, p130PITSLRE is a phosphotyrosine-independent SH2 ligand.

CDK11A CDK11B

4.35e-0627327528743
Pubmed

Localization of the expressed human p58 protein kinase chromosomal gene to chromosome 1p36 and a highly related sequence to chromosome 15.

CDK11A CDK11B

4.35e-0627321774066
Pubmed

Systems-level identification of PKA-dependent signaling in epithelial cells.

PRKACA PRKACB

4.35e-06273228973931
Pubmed

Investigation of -PRKACA/-PRKACB fusion genes in oncocytic tumors of the pancreatobiliary and other systems.

PRKACA PRKACB

4.35e-06273236152045
Pubmed

PRKACA/PRKACB Fusions in Pancreatobiliary Intraductal Oncocytic Papillary Neoplasms Including Those With Atypical Morphology: An Analysis of 22 Cases Expanding Morphologic Spectrum.

PRKACA PRKACB

4.35e-06273238841868
Pubmed

CDK11p58 Promotes Microglia Activation via Inducing Cyclin D3 Nuclear Localization.

CDK11A CDK11B

4.35e-06273228101846
Pubmed

CDK11p110 plays a critical role in the tumorigenicity of esophageal squamous cell carcinoma cells and is a potential drug target.

CDK11A CDK11B

4.35e-06273230722725
Pubmed

Gene Rearrangement and Expression of PRKACA and PRKACB Govern Morphobiology of Pancreatobiliary Oncocytic Neoplasms.

PRKACA PRKACB

4.35e-06273237871652
Pubmed

Molecular and behavioral effects of a null mutation in all PKA C beta isoforms.

PRKACA PRKACB

4.35e-06273212139926
Pubmed

Identification and characterization of a novel cell cycle-regulated internal ribosome entry site.

CDK11A CDK11B

4.35e-06273210882096
Pubmed

The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancer.

CDK11A CDK11B

4.35e-06273227049727
Pubmed

Role of the teneurins, teneurin C-terminal associated peptides (TCAP) in reproduction: clinical perspectives.

TENM1 ADGRL1

4.35e-06273226485751
Pubmed

Structure and expression of the human p58clk-1 protein kinase chromosomal gene.

CDK11A CDK11B

4.35e-0627321639388
Pubmed

Protein expression pattern of CDK11(p58) during testicular development in the mouse.

CDK11A CDK11B

4.35e-06273215792358
Pubmed

Characterization of genomic clones coding for the C alpha and C beta subunits of mouse cAMP-dependent protein kinase.

PRKACA PRKACB

4.35e-0627322833513
Pubmed

Failure to proliferate and mitotic arrest of CDK11(p110/p58)-null mutant mice at the blastocyst stage of embryonic cell development.

CDK11A CDK11B

4.35e-06273215060143
Pubmed

Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome.

MTOR CYFIP2

4.35e-06273222268788
Pubmed

The Role of CDKs and CDKIs in Murine Development.

CDK9 CDK11A CDK11B

1.15e-052173332731332
Pubmed

Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase.

MTOR RPS6KA1

1.30e-05373215905173
Pubmed

Repression of estrogen receptor alpha by CDK11p58 through promoting its ubiquitin-proteasome degradation.

CDK11A CDK11B

1.30e-05373219122208
Pubmed

The RNP protein, RNPS1, associates with specific isoforms of the p34cdc2-related PITSLRE protein kinase in vivo.

CDK11A CDK11B

1.30e-0537329580558
Pubmed

Molecular cloning of a tissue-specific protein kinase (C gamma) from human testis--representing a third isoform for the catalytic subunit of cAMP-dependent protein kinase.

PRKACA PRKACB

1.30e-0537322342480
Pubmed

Cross-talk between protein kinase A and the MAPK-activated protein kinases RSK1 and MK5.

RPS6KA1 PRKACA

1.30e-05373220849292
Pubmed

Active cAMP-dependent protein kinase incorporated within highly purified HIV-1 particles is required for viral infectivity and interacts with viral capsid protein.

PRKACA PRKACB

1.30e-05373212842892
Pubmed

Involvement of the catalytic subunit of protein kinase A and of HA95 in pre-mRNA splicing.

PRKACA PRKACB

1.30e-05373217594903
Pubmed

Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site.

MTOR RPS6KA1

1.30e-05373211914378
Pubmed

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E.

MTOR RPS6KA1

1.30e-05373212080086
Pubmed

Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A.

RPS6KA1 PRKACA

1.30e-05373212213813
Pubmed

The cyclin-dependent kinase 11(p46) isoform interacts with RanBPM.

CDK11A CDK11B

1.30e-05373214511641
Pubmed

Haploinsufficiency of the cdc2l gene contributes to skin cancer development in mice.

CDK11A CDK11B

1.30e-05373217389615
Pubmed

A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning.

PRKACA PRKACB

1.30e-0537328548807
Pubmed

Epidermal growth factor receptor levels are reduced in mice with targeted disruption of the protein kinase A catalytic subunit.

PRKACA PRKACB

1.30e-05373218380891
Pubmed

The C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikis.

CDK11A CDK11B

1.30e-05373212624090
Pubmed

CDK11 Promotes Cytokine-Induced Apoptosis in Pancreatic Beta Cells Independently of Glucose Concentration and Is Regulated by Inflammation in the NOD Mouse Model.

CDK11A CDK11B

1.30e-05373233664748
Pubmed

Plasma lipidomic profiling in murine mutants of Hermansky-Pudlak syndrome reveals differential changes in pro- and anti-atherosclerotic lipids.

HPS1 HPS6

1.30e-05373230710063
Pubmed

Alteration of a cyclic AMP-dependent protein kinase phosphorylation site in the c-Fos protein augments its transforming potential.

RPS6KA1 PRKACA

1.30e-0537321545828
Pubmed

The paradoxical increase in cortisol secretion induced by dexamethasone in primary pigmented nodular adrenocortical disease involves a glucocorticoid receptor-mediated effect of dexamethasone on protein kinase A catalytic subunits.

PRKACA PRKACB

1.30e-05373219383776
Pubmed

ARHGAP25 Inhibits Pancreatic Adenocarcinoma Growth by Suppressing Glycolysis via AKT/mTOR Pathway.

MTOR ARHGAP25

1.30e-05373233994864
Pubmed

Negative regulation of melanogenesis by phospholipase D1 through mTOR/p70 S6 kinase 1 signaling in mouse B16 melanoma cells.

MTOR RPS6KA1

2.60e-05473215895362
Pubmed

14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation.

RPS6KA1 PRKACA

2.60e-05473210949026
Pubmed

CDK11 complexes promote pre-mRNA splicing.

CDK11A CDK11B

2.60e-05473212501247
Pubmed

CDK11(p58) kinase activity is required to protect sister chromatid cohesion at centromeres in mitosis.

CDK11A CDK11B

2.60e-05473224436071
Pubmed

A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3.

CDK11A CDK11B

2.60e-0547327777541
Pubmed

Protein kinase A-induced phosphorylation of the p65 subunit of nuclear factor-kappaB promotes Schwann cell differentiation into a myelinating phenotype.

PRKACA PRKACB

2.60e-05473218385332
Pubmed

Altered secretion of kidney lysosomal enzymes in the mouse pigment mutants ruby-eye, ruby-eye-2-J, and maroon.

HPS1 HPS6

2.60e-0547326776948
Pubmed

Regulation of the cell-cycle-dependent internal ribosome entry site of the PITSLRE protein kinase: roles of Unr (upstream of N-ras) protein and phosphorylated translation initiation factor eIF-2alpha.

CDK11A CDK11B

2.60e-05473215330758
Pubmed

BLOC-2 subunit HPS6 deficiency affects the tubulation and secretion of von Willebrand factor from mouse endothelial cells.

HPS1 HPS6

2.60e-05473227889498
Pubmed

Cloning of a mouse protein kinase A catalytic subunit pseudogene and chromosomal mapping of C subunit isoforms.

PRKACA PRKACB

2.60e-0547327873880
Pubmed

Glucose-dependent regulation of AMP-activated protein kinase in MIN6 beta cells is not affected by the protein kinase A pathway.

PRKACA PRKACB

2.60e-05473223116618
Pubmed

Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice.

MTOR PRKACA

2.60e-05473224512487
Pubmed

Role of caveolin-1 in the modulation of lipolysis and lipid droplet formation.

PRKACA PRKACB

2.60e-05473215111495
Pubmed

Increased expression of a 58-kDa protein kinase leads to changes in the CHO cell cycle.

CDK11A CDK11B

2.60e-0547322217177
Pubmed

Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2.

CDK11A CDK11B

2.60e-0547329750192
Pubmed

Pale ear and light ear in the house mouse. Mimic mutations in linkage groups XII and XVII.

HPS1 HPS6

2.60e-0547326031677
Pubmed

Cyclin D3/CDK11p58 complex is involved in the repression of androgen receptor.

CDK11A CDK11B

2.60e-05473217698582
Pubmed

Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor.

CDK11A CDK11B

2.60e-0547329115219
Pubmed

Discrete control of TRPV4 channel function in the distal nephron by protein kinases A and C.

PRKACA PRKACB

2.60e-05473223709216
Pubmed

Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase.

RPS6KA1 PRKACA

2.60e-0547328248197
Pubmed

Regulation of protein kinase A activity by p90 ribosomal S6 kinase 1.

RPS6KA1 PRKACA

2.60e-05473219808666
Pubmed

Germline and Mosaic Variants in PRKACA and PRKACB Cause a Multiple Congenital Malformation Syndrome.

PRKACA PRKACB

2.60e-05473233058759
Pubmed

Differential role of PKA catalytic subunits in mediating phenotypes caused by knockout of the Carney complex gene Prkar1a.

PRKACA PRKACB

2.60e-05473221852354
Pubmed

IL-6 impairs myogenic differentiation by downmodulation of p90RSK/eEF2 and mTOR/p70S6K axes, without affecting AKT activity.

MTOR RPS6KA1

4.33e-05573224967341
Pubmed

The PtdIns3-phosphatase MTMR3 interacts with mTORC1 and suppresses its activity.

MTOR MTMR3

4.33e-05573226787466
Pubmed

CDK11(p58) protein kinase activity is associated with Bcl-2 down-regulation in pro-apoptosis pathway.

CDK11A CDK11B

4.33e-05573217516030
Pubmed

Phosphorylation of elongation factor-2 kinase on serine 499 by cAMP-dependent protein kinase induces Ca2+/calmodulin-independent activity.

RPS6KA1 PRKACA

4.33e-05573211171059
Pubmed

Riz maps to distal chromosome 4 near genes involved in tumorigenesis and nerve degeneration.

CDK11A CDK11B

4.33e-0557328679000
Pubmed

Developmentally acquired PKA localisation in mouse oocytes and embryos.

PRKACA PRKACB

4.33e-05573218367160
Pubmed

HIV-1 gp120 induces anergy in naive T lymphocytes through CD4-independent protein kinase-A-mediated signaling.

PRKACA PRKACB

4.33e-05573212972513
Pubmed

Progenitor cell defect correctable by bone marrow transplantation in five independent mouse models of platelet storage pool deficiency.

HPS1 HPS6

4.33e-0557323516713
Pubmed

BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival.

RPS6KA1 PRKACA

4.33e-05573210837486
Pubmed

Genetics of aldehyde dehydrogenase isozymes in the mouse: evidence for multiple loci and localization of Ahd-2 on chromosome 19.

HPS1 HPS6

4.33e-0557327274657
Pubmed

Exome sequencing identifies SLC24A5 as a candidate gene for nonsyndromic oculocutaneous albinism.

HPS1 HPS6

4.33e-05573223364476
Pubmed

Involvement of protein kinase A in patterning of the mouse somatosensory cortex.

PRKACA PRKACB

4.33e-05573216707791
Pubmed

Overexpressing PKIB in prostate cancer promotes its aggressiveness by linking between PKA and Akt pathways.

PRKACA PRKACB

4.33e-05573219483721
Pubmed

Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation.

MTOR RPS6KA1

4.33e-05573218722121
Pubmed

The gene for mouse p58cdc2L1 (Cdc2l1) protein kinase maps to distal mouse chromosome 4.

CDK11A CDK11B

4.33e-0557328199413
Pubmed

Analysis of atherosclerosis susceptibility in mice with genetic defects in platelet function.

HPS1 HPS6

4.33e-0557322369371
Pubmed

PKACs attenuate innate antiviral response by phosphorylating VISA and priming it for MARCH5-mediated degradation.

PRKACA PRKACB

4.33e-05573228934360
Pubmed

Chromosome 19 of the house mouse.

HPS1 HPS6

4.33e-0557324436535
Pubmed

Phosphorylation of PITSLRE p110 isoforms accompanies their processing by caspases during Fas-mediated cell death.

CDK11A CDK11B

4.33e-0557329632733
Pubmed

HIV-1 Tat binds to SH3 domains: cellular and viral outcome of Tat/Grb2 interaction.

PRKACA PRKACB

4.33e-05573221745501
Pubmed

Identification of novel mutations and sequence variation in the Zellweger syndrome spectrum of peroxisome biogenesis disorders.

PEX10 PEX26

4.33e-05573219105186
Pubmed

Protein kinase A (PKA)- and protein kinase C-phosphorylated glia maturation factor promotes the catalytic activity of PKA.

RPS6KA1 PRKACA

4.33e-0557329030586
Pubmed

Effects of [D-Ala1] peptide T-NH2 and HIV envelope glycoprotein gp120 on cyclic AMP dependent protein kinases in normal and psoriatic human fibroblasts.

PRKACA PRKACB

4.33e-0557329540970
Pubmed

PKA-mediated stabilization of FoxH1 negatively regulates ERalpha activity.

PRKACA PRKACB

4.33e-05573219711044
Pubmed

Cyclin T1-dependent genes in activated CD4 T and macrophage cell lines appear enriched in HIV-1 co-factors.

CDK9 CDK11B

4.33e-05573218773076
Pubmed

Protein kinases A and C in post-mortem prefrontal cortex from persons with major depression and normal controls.

PRKACA PRKACB

4.33e-05573219573263
Pubmed

The human HERC family of ubiquitin ligases: novel members, genomic organization, expression profiling, and evolutionary aspects.

HERC3 HERC1

4.33e-05573215676274
Pubmed

Ferritin is secreted via 2 distinct nonclassical vesicular pathways.

HPS1 HPS6

6.48e-05673229074498
Pubmed

Phosphorylation of the neurogenic transcription factor SOX11 on serine 133 modulates neuronal morphogenesis.

PRKACA PRKACB

6.48e-05673230385877
Pubmed

Cyclin-dependent kinase 11(p58) interacts with HBO1 and enhances its histone acetyltransferase activity.

CDK11A CDK11B

6.48e-05673215963510
CytobandEnsembl 112 genes in cytogenetic band chr1p36

DRAXIN MTOR RPS6KA1 PEX10 CDK11A CDK11B FBXO2

1.07e-04681737chr1p36
Cytoband10p15.1

ASB13 TRDMT1

9.18e-042873210p15.1
Cytoband1p36.22

DRAXIN FBXO2

1.60e-03377321p36.22
GeneFamilyCyclin dependent kinases

CDK9 CDK11A CDK11B

5.90e-0526533496
GeneFamilyRho GTPase activating proteins|BCH domain containing

TAGAP ARHGAP25 ARHGAP45

4.23e-0450533721
GeneFamilyMaestro heat like repeat containing

MROH1 MROH2A

4.56e-0411532636
GeneFamilyAAA ATPases|Peroxins

PEX10 PEX26

9.85e-0416532957
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

MTMR3 FGD1

3.71e-033153281
GeneFamilyAnkyrin repeat domain containing

ASB18 ASB13 ANKAR MYO16

5.49e-03242534403
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

ARMC3 ANKAR

7.05e-0343532409
GeneFamilyDNAJ (HSP40) heat shock proteins|C2 tensin-type domain containing

DNAJC13 DNAJB14

9.08e-0349532584
GeneFamilyOlfactory receptors, family 52

OR52W1 OR52P1

9.08e-0349532165
CoexpressionGSE3982_MAST_CELL_VS_MAC_UP

MLC1 PRKACA SLC10A3 ARHGAP25 HERC1 TEX10 CYFIP2

1.27e-06199727M5429
ToppCellAT1-AT2_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

GPC1 ASB18 ABCA4 TMC4 MYO16

6.21e-061587353bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCellfacs-Aorta-Heart-3m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS6KA1 ARHGAP45 JAML WDFY4 CYFIP2

9.64e-06173735513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EXD1 TENM1 FGD1 STIL FBXO2

1.23e-0518273539f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCellwk_08-11-Hematologic-Myeloid-pre-pDC/DC5|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TAGAP RPS6KA1 ARHGAP25 JAML WDFY4

1.23e-05182735fec8a2d6d4099722b8e1bb41222108ed74268fcf
ToppCellfacs-Aorta-Heart-3m-Myeloid-macrophage|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS6KA1 ARHGAP45 JAML WDFY4 CYFIP2

1.23e-05182735df26388c0c46d1c4775103c8e802937b4d4e7470
ToppCellfacs-Aorta-Heart-3m-Myeloid-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS6KA1 ARHGAP45 JAML WDFY4 CYFIP2

1.27e-05183735062ec08d66c923f90fee771b1bf8d98bdc7e6c1b
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TAGAP ARHGAP25 ARHGAP45 WDFY4 CYFIP2

1.48e-05189735a12ca69eebc88725272c89d71a57fc6ce0c06813
ToppCell18-Airway-Immune-Immune|Airway / Age, Tissue, Lineage and Cell class

TAGAP ARHGAP25 ARHGAP45 JAML FBXO2

1.52e-0519073509e6bbe4f1be48153dc6cd647a57a0b531b8bf99
ToppCellAdult-Immune-monocyte-D175|Adult / Lineage, Cell type, age group and donor

SERPINB9 ARHGAP25 ARHGAP45 JAML WDFY4

1.56e-05191735cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCellmedial-Hematologic-Natural_Killer_T|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TAGAP RPS6KA1 ARHGAP25 ARHGAP45 CYFIP2

1.76e-051967356d8430ea37bb5ade25ae6b2b1a05158e72705e66
ToppCellmedial-Hematologic-Natural_Killer_T-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TAGAP RPS6KA1 ARHGAP25 ARHGAP45 CYFIP2

1.76e-05196735510a2359947fc6658515b363f975329697692848
ToppCellmedial-2-Hematologic-Natural_Killer_T|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TAGAP RPS6KA1 ARHGAP25 ARHGAP45 CYFIP2

1.76e-05196735c0a3749b06c47574ab252e96688aec9eea2924de
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TAGAP ARHGAP25 ARHGAP45 JAML WDFY4

1.80e-051977350523aec9713ae21e6b879aa98e07fa2576610d5f
ToppCellFetal_29-31_weeks-Immune|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TAGAP ARHGAP25 ARHGAP45 JAML WDFY4

1.85e-051987355dff131356b8c22743bd27b2b21f86ee6e4a0a0d
ToppCellLymphoid-T_cells_(Cd8+_T_cell)|World / shred on cell class and cell subclass (v4)

TAGAP ARHGAP25 HERC3 JAML

8.05e-05139734c85f50fb536f4df6fa4dbdebe48e1ecea1df1121
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GPC1 TOM1L1 STIL JAML

8.74e-05142734e160f35b3c18e77c4107fe96db5f56227c91785e
ToppCellfacs-GAT-Fat-3m-Lymphocytic-NK_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC1 SERPINB9 TAGAP CYFIP2

1.11e-041517343d07b79ecbcfad13116f0f2b039bd181a7ffe853
ToppCellfacs-MAT-Fat-24m-Lymphocytic-NK_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC1 TAGAP RPS6KA1 STIL

1.14e-04152734fa03262e2853b7d35ef8cdbb652930abad90563c
ToppCellLPS-IL1RA-Myeloid_granulocytic|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA4 TENM1 JAML FBXO2

1.20e-04154734d55fb73461885e1e02061a344ff89624ef4de487
ToppCellLPS-IL1RA-Myeloid_granulocytic-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA4 TENM1 JAML FBXO2

1.20e-0415473443735f7c58cac51855ded486ee8d8729a1b9909e
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-Undetermined|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

TAGAP PRKACB ARHGAP45 WDFY4

1.20e-04154734e16f200391537aa1002b0079481b94e1fb86b9ad
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SERPINB9 ARHGAP25 WDFY4 CYFIP2

1.23e-041557349f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TAGAP JAML WDFY4 CYFIP2

1.26e-04156734af47a4b17342bdb3cb62d7e2d52a81168e588629
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC1 SERPINB9 RPS6KA1 CYFIP2

1.29e-04157734ad8c6eb34f5288288c4066119c17325afefbaafc
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EXD1 MROH2A POLN SDR9C7

1.39e-04160734f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TAGAP ARHGAP45 JAML WDFY4

1.39e-041607347f1b58641ba149d20420fafad34ba78a65a2c701
ToppCelldroplet-Heart-nan-24m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EXD1 TSPO2 JAML WDFY4

1.42e-041617347e60001637ef0f6fc67ef8a36ab80ebb25b0b0ab
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

MTOR CDK11A ARHGAP45 WDFY4

1.45e-04162734810881210e015c788814e4fe8d7a24c929cf2621
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPS6KA1 HERC3 JAML WDFY4

1.45e-04162734388670cf3acef17df971c0d8ae3ce14398945192
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPS6KA1 HERC3 JAML WDFY4

1.45e-041627349333d923225df7bfdf6b3a4c32816751315aec50
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TAGAP ARHGAP45 JAML WDFY4

1.67e-04168734907692c1f03d3c9889ba1bed5a4844e2c379db8e
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARMC3 DRAXIN CFAP210 POLN

1.71e-041697348bca402e144819cb9a8d431d6bf9429be2fff6d6
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPO2 ARHGAP45 JAML CYFIP2

1.75e-0417073426178277bf9c7f2f06b5c0b03d4b69d78e9580c4
ToppCellLPS-IL1RA-Lymphocytic_B-B_cells-B-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TAGAP ARHGAP45 WDFY4 CYFIP2

1.75e-0417073492e0873f618b2fa60c4d555b10f234d5cbcf3325
ToppCellLPS-IL1RA-Lymphocytic_B-B_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TAGAP ARHGAP45 WDFY4 CYFIP2

1.75e-04170734c181991f933b779f99afc3782f292306f209e2ac
ToppCellLPS-IL1RA-Lymphocytic_B|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TAGAP ARHGAP45 WDFY4 CYFIP2

1.75e-0417073456284fbfd1e53f67c8c0b7fba64505a4002adba2
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TAGAP ARHGAP25 TEX10 CYFIP2

1.75e-04170734bda900c836e0f2c1d7b442beb50b672d025b2420
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP25 POLN ARHGAP45 PLOD2

1.87e-041737347456a417c5c1d4ba25f9489065aae322421308a6
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP25 POLN ARHGAP45 PLOD2

1.87e-0417373435586a9e5f15b41609b6224e33eb3aa3cb7e03b7
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP25 POLN ARHGAP45 PLOD2

1.87e-04173734cd635751f999e12b14c0accfa1c4c1fd3c1d4540
ToppCelldroplet-Bladder-Unstain-18m-Hematologic-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARMC3 TAGAP POLN JAML

1.91e-04174734773329bb91b97578df138446cf62101dd0dad758
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP TENM1 ARHGAP45 JAML

2.04e-04177734ffc4c675b25ffe8bd3441ce26dd0984fef4b3b88
ToppCellNS-moderate-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SERPINB9 ARHGAP25 JAML WDFY4

2.04e-04177734de1ffe3df76100d46ca158bdd2fea2ebbd4656b4
ToppCellPBMC-Mild-cDC_11|Mild / Compartment, Disease Groups and Clusters

SERPINB9 TOM1L1 WDFY4 CYFIP2

2.04e-04177734974305e4c0eff90134c4e58cf11b955d1eee0501
ToppCell3'-Adult-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TENM1 ARHGAP25 ARHGAP45 JAML

2.04e-04177734bb496fbec7cacc52847abe2b2714249c47879763
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP ARHGAP45 JAML CYFIP2

2.04e-0417773431201a72b7c1bdb0eff892b7072a35c80fd34727
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP ARHGAP45 JAML CYFIP2

2.04e-0417773489d0131320cd96af8b0ee54f0f4d4771d17ef44e
ToppCelldroplet-Kidney-nan-18m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP ARHGAP45 JAML WDFY4

2.13e-0417973458be9ab455875035978c78ba7d7e4b3c9f3dc4e5
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO4 TENM1 PLOD2 MYO16

2.13e-04179734d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCellfacs-Lung-18m-Hematologic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGAP45 JAML WDFY4 CYFIP2

2.13e-0417973462fd60963203a3db98c83b19292c40cc4421cd94
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ASB13 TENM1 TSHR MYO16

2.17e-041807348f774dcacc1626e4e6492f1eb927b0ed56fbe686
ToppCellfacs-Heart-RA-18m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP ARHGAP45 JAML CYFIP2

2.17e-041807349be0af61d496a29d737bb772ad09864797994299
ToppCellCiliated_cells-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

ANO4 ASB18 ARMC3 CFAP210

2.17e-04180734bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCellNS-moderate-d_0-4-Lymphoid-CTL|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DRAXIN TAGAP ARHGAP45 JAML

2.22e-041817347fb3c1d29c542a3cea7fa654432d501d82df138f
ToppCellfacs-Heart-LV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP DDX52 ARHGAP25 ARHGAP45

2.22e-0418173457f82f54e20e19aa17a2ea22af22e3bc8965d622
ToppCellfacs-Heart-LV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP DDX52 ARHGAP25 ARHGAP45

2.22e-041817348855812c85ef45c1be6bd511619b2dfe5e441264
ToppCell11.5-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

TAGAP ARHGAP45 JAML WDFY4

2.22e-04181734193ee02f547a218b2fc13e1174ea4cff4f8a3450
ToppCelldroplet-Pancreas-Endocrine-21m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP ARHGAP25 ARHGAP45 WDFY4

2.27e-04182734cf32603ad9b9882b0bb873327d58b50dd26a5bd3
ToppCelldroplet-Pancreas-Endocrine-21m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP ARHGAP25 ARHGAP45 WDFY4

2.27e-0418273471cfd0b6d464e3e1b1cca34f423abdf699cda48a
ToppCelldroplet-Limb_Muscle-nan-24m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP25 ARHGAP45 WDFY4 CYFIP2

2.27e-041827346946ab8d91fb8dce5af065f57a13659b8d97ed5c
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-1|TCGA-Skin / Sample_Type by Project: Shred V9

TAGAP ARHGAP25 JAML WDFY4

2.32e-04183734cd00e2cd901df4b3f5f7aed747cc0b47f6d3c811
ToppCelldroplet-Heart-nan-24m-Hematologic-erythrocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPO2 STIL POLN

2.35e-047373330374f4d30519ca8cd9582da1f9f906420e50244
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 MROH2A TENM1 MYO16

2.36e-041847342cbed6462fea2622871bb7e49b0df3d984239281
ToppCellwk_08-11-Hematologic-Myeloid-DC3|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TAGAP RPS6KA1 ARHGAP45 JAML

2.36e-041847347d9294e5a55964903feda135e5bea0338824ed83
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 MROH2A TENM1 MYO16

2.36e-04184734ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 MROH2A TENM1 MYO16

2.36e-041847342b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells-Pre-B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TAGAP TSHR WDFY4 CYFIP2

2.41e-041857340fa7970709dc957dea95fabbd83263a0335babd5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP TSPO2 ALPK3 TSHR

2.41e-0418573405bc89a566b0db90ae06506e067190a4739a0974
ToppCellCOVID-19-lung-B_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

ARHGAP25 ARHGAP45 WDFY4 CYFIP2

2.41e-04185734e8f1ad580f19705b5ca1d7d8867b2125f4891684
ToppCelldroplet-Mammary_Gland-nan-18m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP25 ARHGAP45 WDFY4 CYFIP2

2.46e-04186734124a618a0911aba9fc2a071dc3ca40fc003bb1ed
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TAGAP ARHGAP45 JAML WDFY4

2.46e-04186734fc6e591089c87a66653c8e552be9c0fe0c82ecd5
ToppCellP15-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SERPINB9 TMC4 ARHGAP45 PLOD2

2.46e-04186734521e6e007bbae73e7328153aa170cf04ca3c1093
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASB18 DRAXIN STIL TEX10

2.51e-04187734a2076599b33ae6750961b573bfebcb9036fa4ee8
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASB18 DRAXIN STIL TEX10

2.51e-0418773438ee33295a21db4aae5ba085df033db9693e41c6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASB18 DRAXIN STIL TEX10

2.51e-04187734dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ASB13 TENM1 TSHR MYO16

2.57e-0418873472cbfe9dc0583dbeafa6cb0945fa370d0c808284
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO4 TENM1 PLOD2 MYO16

2.57e-041887348de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MLC1 ARHGAP45 JAML WDFY4

2.62e-04189734a010f3e4da6e9bb23b0b9a7f82ad5cee4e607ecd
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO4 ASB13 TENM1 MYO16

2.62e-0418973499a13b1b669b0cd36e3096632351d9ade25d1173
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TAGAP ARHGAP45 JAML WDFY4

2.67e-04190734e5625feb21915d4545cfad2659745ef180efcb1f
ToppCellPCW_05-06-Hematologic_ErythroMegGranulo-Hem_Granulocytic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TAGAP ARHGAP45 JAML WDFY4

2.67e-041907348e254fc77dd1d2d2a4ce0700af3c37829ca089bf
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TAGAP PRKACB ARHGAP25 CYFIP2

2.67e-04190734d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TAGAP ARHGAP25 ARHGAP45 JAML

2.67e-04190734ba61f04fd38efae01f721ba616252d1372ff1002
ToppCellwk_08-11-Hematologic-Myeloid-DC2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TAGAP RPS6KA1 JAML WDFY4

2.67e-04190734902afe2121593ae08d083c2cea2d1ba9f848574a
ToppCellFetal_29-31_weeks-Immune-B_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TAGAP ARHGAP25 WDFY4 CYFIP2

2.67e-04190734424550418c1bd4eb070cf3c41cf09fa9d89aef37
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TAGAP ARHGAP25 ARHGAP45 JAML

2.67e-041907345a37568000dfc33fcbb59b578c1963fb7cf872ec
ToppCellcontrol-Lymphoid-CTL|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TAGAP PRKACB ARHGAP45 JAML

2.72e-041917348df23473e24cfa51c09986102ddd391ed0f0b9cc
ToppCellFetal_29-31_weeks-Immune-B_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TAGAP ARHGAP25 WDFY4 CYFIP2

2.72e-0419173484452125d1b5b76974e3f9126f611eff16d45c25
ToppCell(3)_MNP-(3)_DC_2|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

SERPINB9 TAGAP ARHGAP45 JAML

2.72e-041917343ff163484af8c12ef4eef87246cf044257fd2547
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DRAXIN ADGRB3 ARHGAP45 JAML

2.72e-0419173447a2afc4102199b4bc76bd01b2967c8016186462
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TAGAP TENM1 ARHGAP45 CYFIP2

2.78e-0419273469a2b04f03a1b82d067018379f7b8a116e954040
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TAGAP MLC1 ARHGAP25 ARHGAP45

2.78e-04192734fd7f034f0d5a5d577dc9e26a15856f5defbdef43
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_proliferating_myeloid_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TAGAP ARHGAP45 JAML WDFY4

2.78e-041927347e7383093efaadceadd4d1f900c2d39cd690102e
ToppCellNS-moderate-d_07-13-Lymphoid|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PRKACB ARHGAP25 ARHGAP45 CYFIP2

2.78e-04192734bd4059bfc2159f5ed8bbb2a5408b56117ca6f8e1
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

TAGAP ARHGAP25 STIL WDFY4

2.83e-0419373408696a99309f5b088692ddac8cca35413b5e810d
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TAGAP ARHGAP45 JAML WDFY4

2.83e-041937349a6c5b7c8e88cf7a261f8e052df1709d2c0a91f0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TAGAP ARHGAP25 WDFY4 DNAJB14

2.89e-041947345cd72330c9d9bb21b6c9d5d35085eade101486d1
ToppCellmoderate-Epithelial-FOXN4+|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TMC4 STIL CPLANE1 PLOD2

2.89e-041947345dffa578149104dda33774361e9e77b227b5f1ce
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte1_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TAGAP ARHGAP45 JAML WDFY4

2.89e-04194734fad22d5cf62016cad979e6943e357106d8d2a4b4
ToppCellcellseq-Immune-Immune_Myeloid-Myeloid_Dendritic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SERPINB9 TAGAP JAML WDFY4

2.89e-0419473474d588de2f84a4ef112fd642f7e112a542d5ef11
DrugMianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A

ASB13 DNAJC13 MTOR HPS6 PRKACA FGD1 KIF3C

2.81e-061987172068_DN
DiseasePEROXISOME BIOGENESIS DISORDER 2B

PEX10 PEX26

5.21e-055682C3550234
Diseaseperoxisomal biogenesis disorder (is_implicated_in)

PEX10 PEX26

1.45e-048682DOID:0080377 (is_implicated_in)
DiseaseHermanski-Pudlak Syndrome

HPS1 HPS6

2.33e-0410682C0079504
DiseaseHermansky-Pudlak syndrome

HPS1 HPS6

2.33e-0410682cv:C0079504
DiseasePEROXISOME BIOGENESIS DISORDER 1A (ZELLWEGER)

PEX10 PEX26

2.84e-0411682C4721541
DiseaseAdrenal Gland Neoplasms

PRKACA TSHR

2.84e-0411682C0001624
DiseaseAdrenal Cancer

PRKACA TSHR

2.84e-0411682C0750887
DiseaseZellweger Spectrum

PEX10 PEX26

4.02e-0413682C3658299
DiseaseInfantile Refsum Disease (disorder)

PEX10 PEX26

4.02e-0413682C0282527
DiseaseZellweger-Like Syndrome

PEX10 PEX26

4.02e-0413682C0751594
DiseasePeroxisome biogenesis disorders

PEX10 PEX26

5.39e-0415682C1832200
DiseaseAdrenoleukodystrophy, Neonatal

PEX10 PEX26

5.39e-0415682C0282525
DiseaseZellweger Syndrome

PEX10 PEX26

6.15e-0416682C0043459
Diseaseneutrophil count

DNAJC13 ARMC3 TAGAP TGFBRAP1 ARHGAP25 TMC4 TSHR PPP2R3C ARHGAP45 JAML

1.20e-0313826810EFO_0004833
DiseaseCharcot-Marie-Tooth disease (implicated_via_orthology)

MTMR3 FGD1

1.40e-0324682DOID:10595 (implicated_via_orthology)
DiseaseIntrahepatic Cholangiocarcinoma

PRKACA PRKACB

1.40e-0324682C0345905
DiseaseExtrahepatic Cholangiocarcinoma

PRKACA PRKACB

1.40e-0324682C3805278
DiseaseLymphatic Metastasis

MTOR TSHR

1.64e-0326682C0024232
DiseaseCholangiocarcinoma

PRKACA PRKACB

1.64e-0326682C0206698

Protein segments in the cluster

PeptideGeneStartEntry
LIYLLKQDPPGIDLA

DDX52

296

Q9Y2R4
SPENLPALVALLLLY

ABCA4

1756

P78363
VLGAVLYKNLDLILP

ADGRB3

761

O60242
LYKALEEPLLLPRAQ

ADGRL1

1336

O94910
KIAKLNIPPRLIDYL

ASB13

261

Q8WXK3
PGLIDSLKNYLLLLL

ALPK3

1156

Q96L96
ILDLLKSEYPVIQLL

ARMC3

196

Q5W041
IELKQELPKYLPALQ

CDK11B

416

P21127
LISYLIPDLPKDLRD

ANO4

901

Q32M45
ALRDLHPLPKIILEY

POLN

521

Q7Z5Q5
PLETIIPILQHLKYK

INTS3

821

Q68E01
YILELIPTLPQLDGL

PPP2R3C

196

Q969Q6
VLPYLLDKALLPLEQ

PEX10

101

O60683
EVLKYIIKLNIPELP

ANKAR

686

Q7Z5J8
LDLIYRDLKPENLLI

PRKACA

161

P17612
KPVHILLSNIYLLLP

OR52W1

276

Q6IF63
NVLKLYLRQLPEPLI

ARHGAP45

831

Q92619
DILLLVNPYKELPIY

MYO16

436

Q9Y6X6
KQLHPQLLLPDDYLD

GPC1

176

P35052
IYLILPEFPLLQDSK

HERC3

506

Q15034
LLPLPKPLQNYLLLE

ASB18

446

Q6ZVZ8
LKILALEATYLLPLR

EXD1

246

Q8NHP7
LLSYLLDLLPPLDCL

HERC1

1081

Q15751
ELKLKYLIIENFIPP

KIF3C

626

O14782
YLDELPEPLLLRVLA

FBXO2

46

Q9UK22
ILMADIYLLLPPVLN

OR51L1

276

Q8NGJ5
PILYLLLPLIFVNKC

SLC10A3

191

P09131
LPPKVLELCILLYSK

PEX26

116

Q7Z412
PYQDLPLLDIKALHK

GDPD2

426

Q9HCC8
ILLANVYLLLPPALN

OR52P1

276

Q8NH57
AKYAPLHLVPLIERL

CYFIP2

1076

Q96F07
EQLPKLLPGILALYK

MROH1

261

Q8NDA8
LPRFLDILLTLDYPK

PLOD2

311

O00469
PQQLLPVLFLLYLLM

OR10H3

21

O60404
LDIVQLYLKPLLIGE

FADS2B

116

A8MWK0
LQDKDLLLGLALPYP

DRAXIN

106

Q8NBI3
LDLIYRDLKPENLLI

PRKACB

161

P22694
LDAKLLYIPLAKLPT

SDR9C7

281

Q8NEX9
PQLLVPDVYLNLKLS

CPLANE1

2571

Q9H799
KLYPLPSARALLEII

DNAJB14

36

Q8TBM8
LLPIELKQELPKYLP

CDK11A

401

Q9UQ88
LLKRILPPGLLAYLE

DNAJC13

651

O75165
PADLLALILLVQDLY

HPS1

231

Q92902
PAELLLLLRTYLPDE

HPS6

701

Q86YV9
PYALDLIDKLLVLDP

CDK9

286

P50750
YLDPPNERLILEALK

DHX40

451

Q8IX18
PQIVALAKLLLDPYY

MTMR3

421

Q13615
NLDDYLHLLLPPIVK

MTOR

1106

P42345
KLPDFLPDLIYTLLL

MROH2A

1241

A6NES4
PVLYQEKLLKPAALL

MROH2A

1376

A6NES4
HILDILPRLQKLPKY

TRDMT1

101

O14717
LPRLQKLPKYILLEN

TRDMT1

106

O14717
LVKLLNPRYNLPLDI

TOM1L1

101

O75674
LPRPNLLLLKHLVYV

TAGAP

201

Q8N103
KLILLPVLLDYSLGL

JAML

6

Q86YT9
SELLPRPLNAKKLYL

SLITRK3

401

O94933
PRYELLLKDYLLKLP

FGD1

521

P98174
PKPELENLELTYELL

TENM1

2446

Q9UKZ4
LTIFPPLMLLLQLDY

OR6C3

151

Q9NZP0
QVLYLPLLPSKVDLQ

CFAP210

31

Q0VFZ6
LQVLYPLLSDPALNL

CHST6

181

Q9GZX3
VVLAPLLYPEKRDIL

CNOT1

221

A5YKK6
LLLESDPKVYSLPLV

STIL

246

Q15468
YILVPLPLEKQIQDL

TGFBRAP1

306

Q8WUH2
LLELPYARKELSLLV

SERPINB9

216

P50453
VASLLKLYLRDLPEP

ARHGAP25

231

P42331
LVQELPLLKLGVNYL

TMC4

381

Q7Z404
PLLLKVLLRYDGLTQ

WDFY4

316

Q6ZS81
LKVLDILLEQYPALI

TEX10

161

Q9NXF1
EDYNLKLELLHPIIP

SUGT1

216

Q9Y2Z0
PINKLAALLLLPYLA

TSPO2

126

Q5TGU0
QVLLLRLPPEYEKEL

SLC30A5

646

Q8TAD4
DYPELAEIALKLLLL

ZBED9

1256

Q6R2W3
YIDPDALKELPLLKF

TSHR

116

P16473
AIKPSYDVLLLLLLL

MLC1

296

Q15049
LGIIYRDLKPENILL

RPS6KA1

181

Q15418