Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentproteasome complex

USP25 PSME2

6.54e-0467122GO:0000502
GeneOntologyCellularComponentendopeptidase complex

USP25 PSME2

1.51e-03102122GO:1905369
GeneOntologyCellularComponentintracellular protein-containing complex

USP25 CCT5 PSME2 PCMTD1

1.70e-03972124GO:0140535
GeneOntologyCellularComponentpeptidase complex

USP25 PSME2

2.54e-03133122GO:1905368
Pubmed

Vaccinia-Related Kinase 2 Controls the Stability of the Eukaryotic Chaperonin TRiC/CCT by Inhibiting the Deubiquitinating Enzyme USP25.

USP25 CCT5

2.29e-06712225755282
Pubmed

Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains.

TCEAL9 FMN1

9.91e-06141228605874
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

CCT5 IQCE FMN1

1.04e-0427712330745168
Pubmed

Combined treatment of human multiple myeloma cells with bortezomib and doxorubicin alters the interactome of 20S proteasomes.

CCT5 PSME2

1.78e-045812230009671
InteractionPSMD14 interactions

CCT5 IQCE PSME2 FMN1 NCOA4

8.16e-06527125int:PSMD14
CoexpressionAtlasratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#5

USP25 TCEAL9 IQCE BCORL1 FMN1

4.24e-05781125ratio_ECTO_vs_SC_2500_K5
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

CCT5 PSME2

9.32e-0450102GAVISH_3CA_MALIGNANT_METAPROGRAM_8_PROTEASOMAL_DEGRADATION
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

CCT5 PSME2

9.32e-0450102GAVISH_3CA_METAPROGRAM_MACROPHAGES_PROTEASOMAL_DEGRADATION
DiseaseHIV Coinfection

CCT5 PSME2

6.50e-04103112C4505456
DiseaseHIV Infections

CCT5 PSME2

6.50e-04103112C0019693
Diseaseskin aging measurement

FMN1 PCMTD1

1.98e-03181112EFO_0008006

Protein segments in the cluster

PeptideGeneStartEntry
HKSEDKPDDPQPKMD

BCORL1

86

Q5H9F3
DSSKDKMLAPDPDPN

SLC16A2

511

P36021
EPEAKEEEEEKPHMP

PAGR1

151

Q9BTK6
DPEKHPEAEKDEMEK

FMN1

301

Q68DA7
MKKEEKEDCPEVPHK

IQCE

466

Q6IPM2
IKDQDPMVPEHPKDE

MAP6

636

Q96JE9
EEKDHNEAMKPEEPP

PCMTD1

316

Q96MG8
PKPEPEKHKDSLNMW

NCOA4

446

Q13772
DKDFSHPQMPKKVED

CCT5

231

P48643
PPPKDDEMETDKQEK

PSME2

71

Q9UL46
KAEEETDEEKPKNPM

USP25

281

Q9UHP3
KMEGKPENESEPKHE

TCEAL9

6

Q9UHQ7