Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainMIM/ABBA

MTSS1 MTSS2

7.60e-062522IPR030127
DomainIMD

MTSS1 MTSS2

7.56e-055522PS51338
DomainIMD

MTSS1 MTSS2

1.13e-046522PF08397
DomainI-BAR_dom

MTSS1 MTSS2

5.82e-0413522IPR013606
DomainCH

MICAL2 NAV3 NAV2

7.87e-0465523SM00033
DomainCH

MICAL2 NAV3 NAV2

9.77e-0470523PF00307
Domain-

MICAL2 NAV3 NAV2

1.02e-03715231.10.418.10
DomainCH

MICAL2 NAV3 NAV2

1.10e-0373523PS50021
DomainCH-domain

MICAL2 NAV3 NAV2

1.19e-0375523IPR001715
DomainWH2

MTSS1 MTSS2

2.02e-0324522PS51082
DomainC2

ITSN1 SYT9 PLCB2

5.80e-03131523PF00168
DomainC2

ITSN1 SYT9 PLCB2

6.56e-03137523SM00239
DomainPDZ

IL16 LRRC7 PARD3

7.11e-03141523PF00595
DomainC2

ITSN1 SYT9 PLCB2

7.24e-03142523PS50004
DomainAAA+_ATPase

NAV3 NAV2 ABCB1

7.53e-03144523IPR003593
DomainAAA

NAV3 NAV2 ABCB1

7.53e-03144523SM00382
DomainPDZ

IL16 LRRC7 PARD3

8.11e-03148523SM00228
Domain-

ITSN1 SYT9 PLCB2

8.11e-031485232.60.40.150
Domain-

IL16 LRRC7 PARD3

8.42e-031505232.30.42.10
DomainPDZ

IL16 LRRC7 PARD3

8.57e-03151523PS50106
DomainPDZ

IL16 LRRC7 PARD3

8.73e-03152523IPR001478
DomainC2_dom

ITSN1 SYT9 PLCB2

1.07e-02164523IPR000008
DomainSH3_1

MYO1E SRGAP1 ITSN1

1.07e-02164523PF00018
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CDK9 ALMS1 FAM13A TTC28 MTOR TEX2 SRGAP1 NAV2 NHS KLC4 PARD3 FOXK1 MTSS2

6.67e-10861551336931259
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ALMS1 TTC28 ITSN1 NHS LRRC7 PARD3 NUP153

1.94e-0726355734702444
Pubmed

PI3K-mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models.

MTOR ABCB1

2.46e-06255227553832
Pubmed

A dual PI3 kinase/mTOR inhibitor BEZ235 reverses doxorubicin resistance in ABCB1 overexpressing ovarian and pancreatic cancer cell lines.

MTOR ABCB1

2.46e-06255232061787
Pubmed

Impulsivity and aggression in alcohol withdrawal syndrome is modulated by the interaction of ZNF804A and mTOR polymorphism.

MTOR ZNF804A

2.46e-06255238216065
Pubmed

Retinal pigment epithelium-derived transforming growth factor-β2 inhibits the angiogenic response of endothelial cells by decreasing vascular endothelial growth factor receptor-2 expression.

TGFB2 KDR

2.46e-06255230256387
Pubmed

PD-L1 Upregulation by the mTOR Pathway in VEGFR-TKI-Resistant Metastatic Clear Cell Renal Cell Carcinoma.

MTOR KDR

7.36e-06355235240013
Pubmed

Connecting COPD GWAS Genes: FAM13A Controls TGFβ2 Secretion by Modulating AP-3 Transport.

TGFB2 FAM13A

7.36e-06355234166600
Pubmed

Thioridazine inhibits angiogenesis and tumor growth by targeting the VEGFR-2/PI3K/mTOR pathway in ovarian cancer xenografts.

MTOR KDR

7.36e-06355224952635
Pubmed

Direct Evidence of Target Inhibition with Anti-VEGF, EGFR, and mTOR Therapies in a Clinical Model of Wound Healing.

MTOR KDR

7.36e-06355225878330
Pubmed

Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans.

NAV3 NAV2

7.36e-06355212079279
Pubmed

Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53.

NAV3 NAV2

7.36e-06355215158073
Pubmed

Adipose-Derived VEGF-mTOR Signaling Promotes Endometrial Hyperplasia and Cancer: Implications for Obese Women.

ALMS1 MTOR

7.36e-06355229133593
Pubmed

Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms.

NAV3 NAV2

7.36e-06355212062803
Pubmed

Mouse multidrug resistance 1a/3 gene is the earliest known endothelial cell differentiation marker during blood-brain barrier development.

KDR ABCB1

7.36e-0635527734734
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CDK9 MRE11 IL16 ALMS1 EP400 TTC28 PKP4 LRP2 PARD3 FOXK1

8.75e-061116551031753913
Pubmed

Hydrogen sulfide promotes angiogenesis by downregulating miR-640 via the VEGFR2/mTOR pathway.

MTOR KDR

1.47e-05455226879375
Pubmed

ABBA regulates plasma-membrane and actin dynamics to promote radial glia extension.

MTSS1 MTSS2

1.47e-05455218413296
Pubmed

Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-γ in NK cells.

MTOR IL22

1.47e-05455232154791
Pubmed

A novel actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis protein.

MTSS1 MTSS2

1.47e-05455214752106
Pubmed

The antihypertension drug doxazosin inhibits tumor growth and angiogenesis by decreasing VEGFR-2/Akt/mTOR signaling and VEGF and HIF-1α expression.

MTOR KDR

1.47e-05455224952732
Pubmed

Resveratrol Increases Anti-Proliferative Activity of Bestatin Through Downregulating P-Glycoprotein Expression Via Inhibiting PI3K/Akt/mTOR Pathway in K562/ADR Cells.

MTOR ABCB1

1.47e-05455226460589
Pubmed

Pharmacogenetics of telatinib, a VEGFR-2 and VEGFR-3 tyrosine kinase inhibitor, used in patients with solid tumors.

KDR ABCB1

2.45e-05555219924384
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

MYO1E MTOR MICAL2 PKP4 NAV2 PARD3 ABCB1

3.11e-0556955730639242
Pubmed

RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repair.

MRE11 RNF169

3.67e-05655230104380
Pubmed

Physical interaction between the histone acetyl transferase Tip60 and the DNA double-strand breaks sensor MRN complex.

MRE11 EP400

3.67e-05655220070254
Pubmed

Ranking novel cancer driving synthetic lethal gene pairs using TCGA data.

MTOR KDR

3.67e-05655227438146
Pubmed

FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration.

IL16 SYT9 ABCB1

4.11e-054255329348145
Pubmed

Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.

NAV3 NAV2

5.13e-05755225065758
Pubmed

Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila.

MTOR NUP153

5.13e-05755216543150
Pubmed

Spatial regulation of VEGF receptor endocytosis in angiogenesis.

KDR PARD3

5.13e-05755223354168
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

CCHCR1 ALMS1 TTC28 ITSN1 PKP4 LRP2 KLC4 CLCC1

5.57e-0585355828718761
Pubmed

Microtubule-associated protein 6 mediates neuronal connectivity through Semaphorin 3E-dependent signalling for axonal growth.

ITSN1 KDR

6.83e-05855226037503
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

CDK9 ALMS1 ZNF280D MTOR PREP PKP4 RRP1

8.68e-0567055722990118
Pubmed

GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.

MTSS1 PARD3

8.78e-05955223446420
Pubmed

Influence of pharmacogenetic variability on the pharmacokinetics and toxicity of the aurora kinase inhibitor danusertib.

KDR ABCB1

8.78e-05955220182906
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

CDK9 RNF169 FAM13A SRGAP1 ITSN1 PKP4 CLCC1 NUP153

9.14e-0591655832203420
Pubmed

ASXL3 bridges BRD4 to BAP1 complex and governs enhancer activity in small cell lung cancer.

CDK9 FOXK1

1.10e-041055232669118
Pubmed

Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase.

PKP4 SDK1 ABCB1

1.20e-046055322889411
Pubmed

Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.

TGFB2 FAM13A

1.34e-041155224621683
Pubmed

Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism.

KDR ABCB1

1.34e-041155220389299
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

RNF169 FAM13A NAV2 NHS KLC4 NUP153

1.41e-0450355616964243
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

RNF169 ALMS1 EP400 TTC28 TEX2 ITSN1 CLCC1

1.51e-0473355734672954
Pubmed

Rudhira/BCAS3 is essential for mouse development and cardiovascular patterning.

TGFB2 KDR

1.89e-041355229618843
Pubmed

Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.

MTSS1 MTSS2

1.89e-041355221406566
Pubmed

RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma.

CDK9 MYO1E NUP153 RRP1

2.05e-0418355428186131
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MRE11 RNF169 FAM13A EP400 ITSN1 PARD3 NUP153

2.11e-0477455715302935
Pubmed

Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling.

KDR PARD3

2.21e-041455221396893
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

MRE11 PKP4 NAV2 NHS LRRC7 PARD3

2.64e-0456555625468996
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

PKP4 NAV2 PNRC2 LRRC7 ZNF804A SDK1 NUP153

2.86e-0481455723251661
Pubmed

Notch signaling regulates remodeling and vessel diameter in the extraembryonic yolk sac.

TGFB2 KDR

2.90e-041655221352545
Pubmed

Upregulation of soluble vascular endothelial growth factor receptor 1 contributes to angiogenesis defects in the placenta of alpha 2B-adrenoceptor deficient mice.

TGFB2 KDR

3.29e-041755217673674
Pubmed

Conserved and Divergent Features of Human and Mouse Kidney Organogenesis.

LRP2 KDR

3.29e-041755229449453
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

ALMS1 TTC28 TEX2 NHS

3.40e-0420955436779422
Pubmed

USP10 deubiquitinates Tau, mediating its aggregation.

PLCB2 FOXK1

3.70e-041855235987808
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

CCHCR1 KIAA1549L LRP2 MBD6 KLC4 ZNF804A

3.90e-0460855616713569
Pubmed

A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular development.

TGFB2 KDR

4.58e-042055212588999
Pubmed

Coronary development is regulated by ATP-dependent SWI/SNF chromatin remodeling component BAF180.

TGFB2 KDR

5.06e-042155218508041
Pubmed

Ubiquitin-specific protease 7 sustains DNA damage response and promotes cervical carcinogenesis.

CDK9 MRE11

5.06e-042155230179224
Pubmed

ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration.

MTOR PARD3

5.06e-042155230985297
Pubmed

Cited2 is required for fetal lung maturation.

TGFB2 KDR

5.56e-042255218358466
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

EP400 ITSN1 KDR ZNF804A NUP153

5.91e-0443055535044719
Pubmed

Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development.

TGFB2 KDR

6.08e-042355225759071
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

ALMS1 TTC28 PKP4 KLC4 PARD3

6.96e-0444655524255178
Pubmed

Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation.

TGFB2 KDR

7.20e-042555216887829
Pubmed

Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development.

LRP2 KDR

7.20e-042555223554936
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MTOR ITSN1 PKP4 LRRC7 PARD3 NUP153 MTSS2

7.79e-0496355728671696
Pubmed

Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation.

LRP2 KDR

7.79e-042655228087629
Pubmed

Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction.

TGFB2 KDR

8.40e-042755235894043
Pubmed

mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation.

MTOR PARD3

8.40e-042755227807348
Pubmed

Roles and functions of HIV-1 Tat protein in the CNS: an overview.

CDK9 ABCB1

8.40e-042755224359561
Pubmed

Deletion of Pdcd5 in mice led to the deficiency of placenta development and embryonic lethality.

MTOR KDR

8.40e-042755228542142
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

MRE11 TTC28 LRRC7 PARD3 CLCC1 NUP153

8.66e-0470855639231216
Pubmed

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

RNF169 MYO1E NUP153

8.78e-0411855330979931
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

CDK9 EP400 MTOR

9.22e-0412055327320910
Pubmed

A human MAP kinase interactome.

KIAA1549L ITSN1 NAV3 NAV2 NUP153

1.02e-0348655520936779
Pubmed

HAND2 Target Gene Regulatory Networks Control Atrioventricular Canal and Cardiac Valve Development.

TGFB2 KDR

1.04e-033055228538179
Pubmed

Proliferative activity of extracellular HIV-1 Tat protein in human epithelial cells: expression profile of pathogenetically relevant genes.

TGFB2 KDR

1.04e-033055215857508
Pubmed

TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin.

MRE11 EP400

1.11e-033155226095369
Pubmed

Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response.

LRP2 ABCB1

1.11e-033155220031551
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

ALMS1 EP400 TTC28

1.16e-0313055312421765
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

CCHCR1 MRE11 MYO1E MTOR CLCC1 NUP153

1.20e-0375455633060197
Pubmed

Cdx2 regulates endo-lysosomal function and epithelial cell polarity.

MYO1E PARD3

1.26e-033355220551175
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

EP400 TTC28 PARD3 SDK1 CLCC1 DMXL1

1.39e-0377755635844135
Pubmed

Host PDZ-containing proteins targeted by SARS-CoV-2.

LRRC7 PARD3

1.41e-033555233864728
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

CDK9 MYO1E PARD3 ABCB1

1.53e-0331355438270169
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

CCHCR1 MRE11 TEX2 ITSN1 LRP2 PARD3 NUP153

1.54e-03108455711544199
Pubmed

Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay.

LRP2 KDR

1.58e-033755216319116
InteractionYWHAH interactions

CDK9 ALMS1 FAM13A MYO1E TTC28 MTOR TEX2 SRGAP1 NAV2 NHS KLC4 PARD3 FOXK1 MTSS2

6.37e-0711025314int:YWHAH
InteractionING5 interactions

CDK9 CCHCR1 EP400 NAV3 NAV2

1.23e-05114535int:ING5
InteractionYWHAG interactions

CDK9 ALMS1 FAM13A TTC28 MTOR SRGAP1 NAV2 NHS KDR KLC4 PARD3 FOXK1 MTSS2

1.52e-0512485313int:YWHAG
GeneFamilyI-BAR domain containing

MTSS1 MTSS2

4.06e-0553721287
CoexpressionLAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2

TTC28 ITSN1 LRP2 NHS PARD3 SDK1

1.86e-06176556M39223
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TTC28 LRP2 NHS PARD3 SDK1 ABCB1

1.16e-071875569d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TTC28 LRP2 NHS PARD3 SDK1 ABCB1

1.24e-071895563b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

TTC28 SRGAP1 NAV3 NAV2 PARD3 SDK1

1.49e-07195556603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCHCR1 ALMS1 SRGAP1 KDR MTSS2

2.64e-061775558ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E MICAL2 NHS PARD3 SDK1

3.19e-06184555d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MRE11 MYO1E NHS ZNF804A SDK1

3.28e-06185555e87e6e097dc29ece8aea671935bde281b99b93ea
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

TTC28 NAV3 NAV2 PARD3 SDK1

3.28e-06185555a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TTC28 LRP2 NHS PARD3 SDK1

3.37e-06186555b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

IL16 SRGAP1 NAV3 NAV2 SDK1

3.46e-0618755592d468dde81125d51daf7abd4703741abe1ab91c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHS PARD3 ZNF804A SDK1 EGFEM1P

3.55e-061885556ee3f8f94ea7bdf652c9575fc65bff08070093a4
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MYO1E ITSN1 NAV2 NHS SDK1

3.55e-06188555b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 NHS PARD3 SDK1 ABCB1

3.64e-0618955528b502611829e4a24caff2562545c7db97686099
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TTC28 LRP2 NHS PARD3 SDK1

3.73e-06190555989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TTC28 LRP2 NHS PARD3 SDK1

3.83e-061915551cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TGFB2 NHS PARD3 ZNF804A SDK1

3.93e-061925556a252e298f8a454623fa9c1c893a7a45a886d694
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

TTC28 LRP2 NHS PARD3 SDK1

3.93e-06192555e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

IL16 SRGAP1 NAV3 NAV2 SDK1

4.03e-0619355599525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

IL16 SRGAP1 NAV3 NAV2 SDK1

4.13e-06194555e93de9428c986b8943fc169258847c650cfab0e5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PKP4 UGT8 NHS PARD3 SDK1

4.24e-061955556477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

IL16 SRGAP1 NAV3 NAV2 SDK1

4.24e-0619555561c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

IL16 SRGAP1 NAV3 NAV2 SDK1

4.24e-06195555aa0add081881d349099d12efca5cdee098038d4e
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

TTC28 NAV3 NHS PARD3 SDK1

4.45e-06197555f1c8936986123a3151140c374fcd62d6705c530b
ToppCellIPF-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

MYO1E PKP4 NAV3 NAV2 ABCB1

4.57e-06198555b8bd1ba268480f54451648e01631b615a3401144
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

IL16 SRGAP1 NAV3 NAV2 SDK1

4.57e-061985553ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

MTSS1 KDR PARD3 SDK1 EGFEM1P

4.79e-06200555ca5401b76ab014080914bf78042d368cf318effa
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1|Neuronal / cells hierarchy compared to all cells using T-Statistic

MTSS1 KDR PARD3 SDK1 EGFEM1P

4.79e-0620055540286010bd17cf9e34ecd5440953b072ebfae208
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IL16 SRGAP1 NAV3 NAV2 SDK1

4.79e-06200555cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IL16 SRGAP1 NAV3 NAV2 SDK1

4.79e-06200555e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3|Neuronal / cells hierarchy compared to all cells using T-Statistic

TGFB2 NHS PARD3 ZNF804A SDK1

4.79e-062005557e51715525fdb001b7042b2bfcb9de81ecb5e4ee
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1--L2-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

MTSS1 KDR PARD3 SDK1 EGFEM1P

4.79e-0620055570c47d3bbe67d88c5b9dff99c33a603d25fa2ab0
ToppCellEndothelial-endothelial_cell_of_bronchial_vessel|World / Lineage, Cell type, age group and donor

PKP4 NAV3 KDR ABCB1

5.14e-0516555484e553d699ac56df89a77248f7308b9133e1b683
ToppCellPosterior_cortex-Neuronal-Inhibitory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MTSS1 NHS ZNF804A MTSS2

5.39e-051675549a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL16 MICAL2 NAV3 LRRC7

5.51e-051685544b2d29a7843bf45922038c093ca7ec0600756adc
ToppCellControl|World / group, cell type (main and fine annotations)

MICAL2 LRP2 NAV2 PARD3

5.51e-05168554a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP2 NHS SDK1 ABCB1

5.51e-05168554a086c306be430adf0632ba53e98cd8014d2de330
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL16 MICAL2 NAV3 LRRC7

5.91e-051715545d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

TGFB2 TTC28 LRP2 SDK1

6.04e-0517255436a96714a0eb6ac438648135336c9791881ddadb
ToppCellControl-Endothelial_cells-Systemic_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

PKP4 NAV3 KDR ABCB1

6.04e-05172554c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SRGAP1 NHS PARD3 SDK1

6.18e-05173554af85fb9f6e26a044ca4d23e5872039b1a7b73b1b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-5_VIP_KCNJ2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SRGAP1 PARD3 ZNF804A SDK1

6.32e-05174554fdadac1eaab2c4a67e4832f0901df22e893add6a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TGFB2 PARD3 ZNF804A SDK1

6.46e-051755549d09636a103daa8f622c3dbfd1f1536aaec3b6bb
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MICAL2 UGT8 ZNF804A CHRNB4

6.46e-0517555419eda8b5d39dc93d79737ebdbeeba5ec0cb23c51
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MTOR METTL4 KLC4 DMXL1

6.75e-0517755436b5d29caa9cffbc0284f771a4db71aa72171a89
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E SRGAP1 MTSS1 ZNF804A

6.75e-051775544d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SRGAP1 SDK1 EGFEM1P ABCB1

6.75e-05177554bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP2 NHS PARD3 SDK1

6.90e-05178554544379f5a6145429762258d426b876bb36c112f5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E SRGAP1 MTSS1 ZNF804A

6.90e-05178554edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP1 NAV2 NHS PARD3

6.90e-05178554a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SRGAP1 SDK1 EGFEM1P ABCB1

7.05e-051795547954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SRGAP1 NHS ZNF804A SDK1

7.05e-051795543b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MTOR METTL4 KLC4 DMXL1

7.21e-05180554a682a5d55c612709c9ee9fa4289d6f8bef7fe1af
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SRGAP1 NHS PARD3 SDK1

7.21e-05180554b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SRGAP1 NHS ZNF804A SDK1

7.36e-05181554153709b4dd3d81e09f251fa8765b58bed1932fda
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E SRGAP1 MTSS1 ZNF804A

7.36e-051815545bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MTSS1 PARD3 SDK1 EGFEM1P

7.36e-0518155435bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E SRGAP1 MTSS1 ZNF804A

7.36e-051815548e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

FAM13A NAV2 PARD3 SDK1

7.36e-05181554c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TGFB2 PARD3 ZNF804A SDK1

7.52e-05182554d3a037268f026eb2f84428b1821022503cef7756
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MTSS1 NHS PARD3 SDK1

7.52e-05182554420a8fd30543e37a66ba0786215d056d308660d0
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP2 UGT8 NHS ABCB1

7.52e-051825549d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DHX58 SRGAP1 MTSS1 KDR

7.68e-05183554e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PARD3 ZNF804A SDK1 EGFEM1P

7.85e-0518455432473dbdb2de66391157c5814ef34e790806e4f2
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHS PARD3 ZNF804A SDK1

7.85e-05184554c4c1a3d279ca733b865ce46570d7642dc137f9a4
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHS PARD3 ZNF804A SDK1

7.85e-051845542ba98708dfd7f1b2a661578a334684094ff453ad
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MICAL2 NAV3 NAV2 LRRC7

7.85e-05184554e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellControl-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

TGFB2 SRGAP1 NHS KDR

8.01e-051855546814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SRGAP1 ITSN1 MTSS1 NAV2

8.01e-051855548207f9eff113eed429e961748c6b17d672a13b33
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

MYO1E PKP4 KDR ABCB1

8.01e-05185554f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TTC28 NHS PARD3 SDK1

8.01e-05185554027020754dbf71b0034791f9a34ae795e3b85f81
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TGFB2 PARD3 ZNF804A SDK1

8.01e-051855540b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E SRGAP1 MTSS1 ZNF804A

8.01e-05185554b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E SRGAP1 MTSS1 ZNF804A

8.01e-051855549197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E SRGAP1 MTSS1 ZNF804A

8.01e-05185554ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 NHS PARD3 SDK1

8.18e-05186554f28d72b47624b69a580b4429e2be560a26898591
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MTSS1 NHS PARD3 SDK1

8.35e-05187554ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MYO1E NAV2 NHS SDK1

8.35e-051875547e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

LRP2 NHS PARD3 SDK1

8.35e-05187554d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

SRGAP1 NAV3 NAV2 SDK1

8.35e-05187554e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E SYT9 SDK1 ABCB1

8.35e-05187554e3095455d2f255854f339f6b05fa87852af0700f
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

TTC28 NAV3 KDR ABCB1

8.52e-05188554117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

MYO1E MICAL2 NHS SDK1

8.52e-0518855434e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHS KDR SDK1 EGFEM1P

8.52e-051885543139540a656c0436b2123ea50741ff8d00112165
ToppCellControl-Endothelial-VE_Peribronchial|World / Disease state, Lineage and Cell class

PKP4 NAV3 KDR ABCB1

8.70e-05189554c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E SYT9 SDK1 ABCB1

8.70e-05189554fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYO1E MICAL2 NHS SDK1

8.70e-051895546b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E PKP4 NAV2 NHS

8.70e-051895548c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1E PKP4 NAV2 NHS

8.70e-051895545d902a4660a27548764bf04c6de152b565da835c
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

LRP2 NHS PARD3 SDK1

8.70e-051895540be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MICAL2 SRGAP1 NAV2 NUP153

8.88e-051905541121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MICAL2 SRGAP1 NAV2 NUP153

8.88e-05190554048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 NHS PARD3 SDK1

9.06e-051915543c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 NHS PARD3 SDK1

9.06e-051915541c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PKP4 NAV2 UGT8 NHS

9.06e-05191554963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellE15.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TGFB2 FAM13A NAV2 DNASE2

9.06e-05191554402c341b00f98e8215458766b3c219fff8dcb447
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO1E PKP4 KDR ABCB1

9.06e-05191554a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL16 NAV3 NAV2 SDK1

9.06e-051915546688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL16 NAV3 NAV2 SDK1

9.25e-0519255499ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MTSS1 NHS PARD3 SDK1

9.25e-051925543abee376c37c3646da33ac381aa63d50a01607a6
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MTSS1 NHS PARD3 SDK1

9.25e-0519255467d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NHS PARD3 ZNF804A SDK1

9.25e-05192554025fac36b862f9ca7f96fb4a1946c44ba7cbc382
ComputationalNeighborhood of PTPRB

IL16 FAM13A KDR CHRNB4 ABCB1

5.29e-04254295MORF_PTPRB
ComputationalNeighborhood of FSHR

IL16 FAM13A KDR CHRNB4 ABCB1

8.09e-04279295MORF_FSHR
ComputationalGenes in the cancer module 178.

TNFSF12 KDR

9.32e-0417292MODULE_178
ComputationalGenes in the cancer module 444.

TNFSF12 KDR

1.05e-0318292MODULE_444
ComputationalNeighborhood of MLLT10

IL16 FAM13A KDR CHRNB4 ABCB1

1.16e-03302295MORF_MLLT10
ComputationalNeighborhood of PRKCA

IL16 FAM13A CHRNB4 ABCB1

1.33e-03181294MORF_PRKCA
ComputationalAngiogenesis.

TNFSF12 KDR

1.43e-0321292MODULE_362
Diseasebiological sex

ZNF280D TTC28 ITSN1 PKP4 LRRC7 PARD3 SDK1

1.58e-07230527PATO_0000047
Diseaseintellectual developmental disorder with ocular anomalies and distinctive facial features (implicated_via_orthology)

MTSS1 MTSS2

3.05e-062522DOID:0081301 (implicated_via_orthology)
Diseasecarotid artery intima media thickness

FAM13A PREP NAV2 LRRC7 METTL4 ZNF804A FOXK1

1.36e-05450527EFO_0007117
Diseasecolorectal adenocarcinoma (is_implicated_in)

IL16 KDR ABCB1

3.25e-0535523DOID:0050861 (is_implicated_in)
Diseaseasthma (is_marker_for)

IL16 IL22 KDR ABCB1

7.32e-05126524DOID:2841 (is_marker_for)
DiseaseMalignant Neoplasms

MRE11 MTOR KDR ABCB1

7.78e-05128524C0006826
Diseasetemporal lobe epilepsy (implicated_via_orthology)

MTOR ABCB1

1.09e-049522DOID:3328 (implicated_via_orthology)
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

MTOR NAV3 KDR ZNF804A

1.36e-04148524C0279702
Diseaseattempted suicide

KIAA1549L FAM13A NAV3 LRP2

2.76e-04178524EFO_0004321
Diseasevital capacity

TGFB2 FAM13A MYO1E TNFSF12 LRP2 KDR PARD3 TSGA10IP FOXK1

2.79e-041236529EFO_0004312
DiseaseN-acetylmethionine measurement

ALMS1 MICAL2

3.15e-0415522EFO_0021427
Diseaseperipheral arterial disease, traffic air pollution measurement

TGFB2 IL16 MTSS1 NAV2

3.83e-04194524EFO_0004265, EFO_0007908
Diseasecerebral microbleeds

SRGAP1 ABCB1

5.11e-0419522EFO_0010059
Diseaseend stage renal disease (implicated_via_orthology)

MTOR ABCB1

5.67e-0420522DOID:783 (implicated_via_orthology)
Diseasemalignant astrocytoma (is_marker_for)

MRE11 IL16

7.53e-0423522DOID:3069 (is_marker_for)
DiseaseDupuytren Contracture

MYO1E KDR SDK1

9.25e-04108523EFO_0004229
Diseasecup-to-disc ratio measurement

TGFB2 KIAA1549L TTC28 NAV2 FOXK1

9.50e-04430525EFO_0006939
Diseaseblood chromium measurement

KIAA1549L MICAL2

9.64e-0426522EFO_0007579
Diseasecreatinine measurement, glomerular filtration rate

ALMS1 LRP2 EGFEM1P

1.17e-03117523EFO_0004518, EFO_0005208
DiseaseToxic Encephalitis

MTOR ABCB1

1.20e-0329522C0154659
DiseaseNeurotoxicity Syndromes

MTOR ABCB1

1.20e-0329522C0235032
DiseaseEncephalopathy, Toxic

MTOR ABCB1

1.20e-0329522C0149504
DiseasePapillary Renal Cell Carcinoma

MTOR NAV3 ZNF804A

1.51e-03128523C1306837
DiseaseRenal Cell Carcinoma

MTOR NAV3 ZNF804A

1.51e-03128523C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

MTOR NAV3 ZNF804A

1.51e-03128523C1266043
DiseaseChromophobe Renal Cell Carcinoma

MTOR NAV3 ZNF804A

1.51e-03128523C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

MTOR NAV3 ZNF804A

1.51e-03128523C1266044

Protein segments in the cluster

PeptideGeneStartEntry
SSYSSPAREQNRRLQ

PKP4

1096

Q99569
LNRVNPSSYSRGLKN

ZNF280D

61

Q6N043
NKTRYNNLIRPATSS

CHRNB4

36

P30926
KSKNNRPLRTSQIYA

EP400

2436

Q96L91
LSPRRIKLYSSITNQ

ALMS1

3801

Q8TCU4
RLAVAYKQPASNSRS

DMXL1

1056

Q9Y485
AQSLQVPYRNSLRKA

ABCB1

921

P08183
KRAASLNYLNQPSAA

KLC4

586

Q9NSK0
KYNPTRNSNSSRQDI

MBD6

956

Q96DN6
VKNLTQRRPLSARSY

LRRC7

1191

Q96NW7
RYNIPAPQSRNVSKN

PNRC2

6

Q9NPJ4
NYRRLIQTKRPASTA

MTSS2

526

Q765P7
YRSSNLAQQAPVRLS

MTSS1

301

O43312
YSNITVPSRKNTQLR

NAV3

911

Q8IVL0
PYSLCSNRKSLSQQL

IL16

166

Q14005
MKNSVYRSRQSLNSP

KIAA1549L

1466

Q6ZVL6
KTRRTVVQYLNNPRS

LRP2

816

P98164
ISRNLYSTNPRTQSI

LRP2

1831

P98164
RQRSNTLPKSFGSQL

FAM13A

736

O94988
RTNQVILTAPNRSSY

NPC1L1

406

Q9UHC9
TFKTNRQSPNYRVIN

PREP

301

P48147
GRSLQPLYRSNTSQL

DNASE2

76

O00115
AVPQSSRLKYRQLFN

ITSN1

216

Q15811
VINNPSYRQRAQKLS

UGT8

416

Q16880
KILQRQFSSSNSPRG

DHX58

356

Q96C10
NLSLNRYFIKVPRSQ

FOXK1

356

P85037
QLPSLNNRLSYAVRK

CCHCR1

456

Q8TD31
LAKNSQPNRYTNRVV

CDK9

176

P50750
LSRRSSPMKYQQNVS

EGFEM1P

151

Q0D2K5
RTKQRYNNPRSLSTK

SEC22A

121

Q96IW7
SISRLQNPRYKVLAS

SDK1

426

Q7Z5N4
KRSNRYSYLSPLQIQ

METTL4

296

Q8N3J2
KSSISNNYLNLTFPR

MICAL2

646

O94851
QAQRQYSSLPRQSRK

PARD3

1216

Q8TEW0
YSSLPRQSRKNASSV

PARD3

1221

Q8TEW0
NDPTSLRKNLSIQRY

MTOR

2211

P42345
RKTSTKRNTLNPVYN

SYT9

406

Q86SS6
FSQRQSRRKSTANLP

TSGA10IP

141

Q3SY00
RKSRPRSQYNTKLFN

SRGAP1

491

Q7Z6B7
LNDLKTNDPYRSLSN

NHS

951

Q6T4R5
LQYRSLPRPSKSNSR

NAV2

1211

Q8IVL1
ASRQSTPSQNRKRLY

RRP1

311

P56182
PRNLNRSLQKQTSYE

RNF169

411

Q8NCN4
RLDKSNFQQPYITNR

IL22

41

Q9GZX6
STRQQPSRNVTTKNY

MRE11

626

P49959
SQSNPVFRRYLNKIL

CLCC1

91

Q96S66
LPSYRLESQQTNRRK

TGFB2

286

P61812
VKSYNQASTRSRPQS

SRRM5

266

B3KS81
AAVRQSKLRNTPYQA

NUP153

271

P49790
RRYRTKLSPSTNSIN

PLCB2

716

Q00722
SKNAYLQRSTLPRSQ

TTC28

2026

Q96AY4
RLYNTRGKSLTQNSA

ZNF26

126

P17031
TQNSAPSRSYLRKNP

ZNF26

136

P17031
ARINSSSPLRYNRQI

TNFSF12

136

O43508
SQYLQNSKRKSRPVS

KDR

1221

P35968
LSKPNKNISRRASYN

TEX2

581

Q8IWB9
NIERNFRQSQPKSYL

ZNF804A

956

Q7Z570
QRSNQKSLYTSMARP

MYO1E

981

Q12965