Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	ARM-type_fold	IPO5 CUL9 RELCH RYR3	7.19e-04	339	23	4	IPR016024
Domain	-	IPO5 CUL9 RELCH	2.46e-03	222	23	3	1.25.10.10
Domain	HEAT_REPEAT	IPO5 RELCH	3.33e-03	70	23	2	PS50077
Domain	ARM-like	IPO5 CUL9 RELCH	4.27e-03	270	23	3	IPR011989
Domain	C2	FER1L6 RAB11FIP1	1.12e-02	131	23	2	PF00168
Domain	C2	FER1L6 RAB11FIP1	1.22e-02	137	23	2	SM00239
Pubmed	The landscape of genetic mutations in patients with chronic lymphocytic leukaemia and complex karyotype.	SETD2 NOTCH1	4.18e-07	2	23	2	31344256
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	WEE1 CUL9 ATXN7L3 ELL3 SETD2 RAB11FIP1 IYD	5.37e-06	1116	23	7	31753913
Pubmed	Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3.	PLA2G7 RYR3	7.10e-05	19	23	2	31847788
Pubmed	Histone Lysine Methyltransferase SETD2 Regulates Coronary Vascular Development in Embryonic Mouse Hearts.	SETD2 NOTCH1	9.59e-05	22	23	2	33898448
Pubmed	Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays.	WEE1 TRIM52 ERMN	3.18e-04	203	23	3	19953087
Pubmed	Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development.	PLA2G7 NOTCH1	4.25e-04	46	23	2	23555292
Interaction	ZNF445 interactions	CUL9 TRIM52 LDOC1 ZSCAN20	4.89e-07	57	23	4	int:ZNF445
CoexpressionAtlas	FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#3	IPO5 PLA2G7 RAB11FIP1 ERMN	3.39e-05	182	22	4	Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K3
Disease	Squamous cell carcinoma of the head and neck	WEE1 NOTCH1	5.67e-04	52	20	2	C1168401
Disease	eotaxin measurement	HFM1 PDZD2	1.34e-03	80	20	2	EFO_0008122
Disease	sleep duration	IPO5 CUL9 PDZD2	1.79e-03	362	20	3	EFO_0005271
Disease	Adenoid Cystic Carcinoma	SETD2 NOTCH1	2.08e-03	100	20	2	C0010606
Disease	Squamous cell carcinoma	SEM1 NOTCH1	3.17e-03	124	20	2	C0007137
Disease	Malignant Neoplasms	SETD2 NOTCH1	3.37e-03	128	20	2	C0006826
Disease	retinal vasculature measurement	IPO5 SEM1 PDZD2	4.88e-03	517	20	3	EFO_0010554
Disease	alcohol use disorder (implicated_via_orthology)	NOTCH1 RYR3	7.63e-03	195	20	2	DOID:1574 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
NQDLQEGEDWEQEDE	ELL3	246	Q9HB65
SDQEDNDDINDNDWS	ATXN7L3	131	Q14CW9
DENDDQDFELWDDVG	RELCH	281	Q9P260
MDDNQNEWGDEDLET	NOTCH1	1806	P46531
KQCFGWDDDEDDDDE	LDOC1	126	O95751
DAQFWQEEEGDFDEQ	GPATCH3	341	Q96I76
QEEEGDFDEQTADDW	GPATCH3	346	Q96I76
ETFNDWSDDNIFDDE	PCNX4	816	Q63HM2
EDVSSWTDNEDQEAD	PDZD2	441	O15018
WTDNEDQEADGEEDE	PDZD2	446	O15018
WANADELEDDDFDSN	IPO5	321	O00410
VWDEEIDDDDDDNCN	ERMN	181	Q8TAM6
DFDQWDCLIEGDDEN	PLA2G7	401	Q13093
LGNEVWDDFDDENLE	HFM1	1266	A2PYH4
WQQDEFDEELDNDSF	CUL9	2476	Q8IWT3
QFWNDDDSEGDNESE	PARP6	6	Q2NL67
QAEEDADEWQESEEN	IYD	56	Q6PHW0
DGDLESEFNNFEDWV	FER1L6	1281	Q2WGJ9
GDFQSQWDEDDNEDE	RAB11FIP1	251	Q6WKZ4
DNWDDDNVEDDFSNQ	SEM1	41	P60896
ADEELFQDQDDDELW	TRIM52	91	Q96A61
NAASEEGDEDDWASN	WEE1	441	P30291
LDWGEDSENENEDEG	ZSCAN20	661	P17040
ANLWNSFNDEEEEEA	RYR3	4446	Q15413
EEEENWDQQDGSHFS	SETD2	1336	Q9BYW2