Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

CHD3 CHD5

1.82e-0437112GO:0140658
GeneOntologyMolecularFunctionhistone binding

CHD3 ATAD2 CHD5

3.52e-04265113GO:0042393
GeneOntologyMolecularFunctionATP hydrolysis activity

CHD3 ATAD2 CHD5

1.55e-03441113GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

CHD3 CHD5

2.13e-03127112GO:0008094
GeneOntologyMolecularFunctionhelicase activity

CHD3 CHD5

3.27e-03158112GO:0004386
GeneOntologyMolecularFunctionATP-dependent activity

CHD3 ATAD2 CHD5

3.97e-03614113GO:0140657
GeneOntologyMolecularFunctionenzyme regulator activity

BRPF1 PPP6R1 PIK3R5 FBXW7

5.57e-031418114GO:0030234
GeneOntologyMolecularFunctionchromatin binding

CHD3 ATAD2 CHD5

6.67e-03739113GO:0003682
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

CHD3 ATAD2 CHD5

7.61e-03775113GO:0017111
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

CHD3 CHD5

8.72e-03262112GO:0140097
GeneOntologyMolecularFunctionpyrophosphatase activity

CHD3 ATAD2 CHD5

9.47e-03839113GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

CHD3 ATAD2 CHD5

9.50e-03840113GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

CHD3 ATAD2 CHD5

9.50e-03840113GO:0016818
GeneOntologyCellularComponentCHD-type complex

CHD3 CHD5

3.41e-0517112GO:0090545
GeneOntologyCellularComponentNuRD complex

CHD3 CHD5

3.41e-0517112GO:0016581
GeneOntologyCellularComponenthistone deacetylase complex

CHD3 CHD5

8.78e-0485112GO:0000118
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

CHD3 CHD5

1.12e-0396112GO:0070603
GeneOntologyCellularComponentcentriolar satellite

CHD3 PIK3R5

1.97e-03128112GO:0034451
GeneOntologyCellularComponentATPase complex

CHD3 CHD5

2.00e-03129112GO:1904949
GeneOntologyCellularComponentchromatin

CHD3 BRPF1 CHD5 FERD3L

5.52e-031480114GO:0000785
GeneOntologyCellularComponentnuclear body

RBM19 CHD3 CHD5

1.02e-02903113GO:0016604
GeneOntologyCellularComponenttransferase complex

BRPF1 PIK3R5 FBXW7

1.22e-02963113GO:1990234
GeneOntologyCellularComponentnuclear speck

RBM19 CHD5

2.06e-02431112GO:0016607
DomainCHDCT2

CHD3 CHD5

9.46e-073112PF08074
DomainCHDNT

CHD3 CHD5

9.46e-073112PF08073
DomainDUF1086

CHD3 CHD5

9.46e-073112IPR009462
DomainDUF1087

CHD3 CHD5

9.46e-073112IPR009463
DomainDUF1087

CHD3 CHD5

9.46e-073112PF06465
DomainDUF1086

CHD3 CHD5

9.46e-073112PF06461
DomainDUF1087

CHD3 CHD5

9.46e-073112SM01147
DomainDUF1086

CHD3 CHD5

9.46e-073112SM01146
DomainCHD_N

CHD3 CHD5

9.46e-073112IPR012958
DomainCHD_C2

CHD3 CHD5

9.46e-073112IPR012957
DomainZinc_finger_PHD-type_CS

CHD3 BRPF1 CHD5

6.51e-0665113IPR019786
DomainZnf_PHD-finger

CHD3 BRPF1 CHD5

1.17e-0579113IPR019787
DomainPHD

CHD3 BRPF1 CHD5

1.68e-0589113SM00249
DomainZnf_PHD

CHD3 BRPF1 CHD5

1.79e-0591113IPR001965
DomainZF_PHD_2

CHD3 BRPF1 CHD5

2.04e-0595113PS50016
DomainZF_PHD_1

CHD3 BRPF1 CHD5

2.11e-0596113PS01359
DomainZnf_FYVE_PHD

CHD3 BRPF1 CHD5

7.53e-05147113IPR011011
DomainChromo_domain

CHD3 CHD5

8.64e-0524112IPR023780
DomainChromo

CHD3 CHD5

1.02e-0426112PF00385
DomainCHROMO_2

CHD3 CHD5

1.18e-0428112PS50013
DomainCHROMO_1

CHD3 CHD5

1.18e-0428112PS00598
DomainSNF2_N

CHD3 CHD5

1.55e-0432112PF00176
DomainSNF2_N

CHD3 CHD5

1.55e-0432112IPR000330
DomainChromodomain-like

CHD3 CHD5

1.55e-0432112IPR016197
DomainCHROMO

CHD3 CHD5

1.65e-0433112SM00298
DomainChromo/shadow_dom

CHD3 CHD5

1.65e-0433112IPR000953
DomainDNA/RNA_helicase_DEAH_CS

CHD3 CHD5

1.86e-0435112IPR002464
DomainBROMODOMAIN_1

ATAD2 BRPF1

2.08e-0437112PS00633
DomainBromodomain

ATAD2 BRPF1

2.19e-0438112PF00439
DomainDEAH_ATP_HELICASE

CHD3 CHD5

2.19e-0438112PS00690
DomainBROMODOMAIN_2

ATAD2 BRPF1

2.55e-0441112PS50014
DomainBROMO

ATAD2 BRPF1

2.68e-0442112SM00297
DomainBromodomain

ATAD2 BRPF1

2.68e-0442112IPR001487
Domain-

ATAD2 BRPF1

2.68e-04421121.20.920.10
Domain-

CHD3 CHD5

4.60e-04551121.10.30.10
DomainHMG_box_dom

CHD3 CHD5

6.43e-0465112IPR009071
DomainPHD

CHD3 CHD5

8.55e-0475112PF00628
DomainHelicase_C

CHD3 CHD5

1.73e-03107112PF00271
DomainHELICc

CHD3 CHD5

1.73e-03107112SM00490
DomainHelicase_C

CHD3 CHD5

1.76e-03108112IPR001650
DomainHELICASE_CTER

CHD3 CHD5

1.79e-03109112PS51194
DomainHELICASE_ATP_BIND_1

CHD3 CHD5

1.79e-03109112PS51192
DomainDEXDc

CHD3 CHD5

1.79e-03109112SM00487
DomainHelicase_ATP-bd

CHD3 CHD5

1.83e-03110112IPR014001
Domain-

CHD3 BRPF1 CHD5

1.97e-034491133.30.40.10
DomainZnf_RING/FYVE/PHD

CHD3 BRPF1 CHD5

2.10e-03459113IPR013083
Domain-

CHD3 ATAD2 CHD5

8.23e-037461133.40.50.300
DomainP-loop_NTPase

CHD3 ATAD2 CHD5

1.17e-02848113IPR027417
DomainRING

CHD3 CHD5

1.33e-02305112SM00184
DomainZnf_RING

CHD3 CHD5

1.51e-02326112IPR001841
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION

CHD3 BRPF1

1.46e-042992MM15340
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION

CHD3 BRPF1

1.56e-043092M27637
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

CHD3 ATAD2 BRPF1 CHD5 NOL4

6.80e-0760811536089195
Pubmed

DLX1 and the NuRD complex cooperate in enhancer decommissioning and transcriptional repression.

CHD3 CHD5

9.53e-061511235695185
Pubmed

A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.

CHD3 CHD5

1.23e-051711227806305
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CHD3 BRPF1 CHD5 PPP6R1 NOL4

1.33e-05111611531753913
Pubmed

Human transcription factor protein interaction networks.

CHD3 CHD5 PPP6R1 NOL4 FBXW7

4.37e-05142911535140242
Pubmed

Identification of the BRD1 interaction network and its impact on mental disorder risk.

CHD3 CHD5

5.38e-053511227142060
Pubmed

Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.

CHD3 CHD5

6.35e-053811233283408
Pubmed

The functional interactome landscape of the human histone deacetylase family.

CHD3 ATAD2 PPP6R1

8.92e-0528911323752268
Pubmed

BioID-based proteomic analysis of the Bid interactome identifies novel proteins involved in cell-cycle-dependent apoptotic priming.

CHD3 CHD5

1.34e-045511233067418
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

ATAD2 BRPF1

2.49e-047511225593309
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

CHD3 PPP6R1 NOL4

2.65e-0441811334709266
InteractionZMYND8 interactions

CHD3 BRPF1 CHD5 FBXW7

2.45e-06191114int:ZMYND8
InteractionH3C3 interactions

CHD3 ATAD2 BRPF1 CHD5 NOL4

3.58e-06495115int:H3C3
InteractionRPL7A interactions

RBM19 CHD3 ATAD2 PPP6R1 FBXW7

1.67e-05679115int:RPL7A
InteractionSHPRH interactions

CHD3 CHD5 FBXW7

1.73e-0597113int:SHPRH
InteractionHP1BP3 interactions

RBM19 CHD3 BRPF1 FBXW7

2.10e-05329114int:HP1BP3
InteractionH3-3A interactions

CHD3 ATAD2 BRPF1 CHD5 NOL4

2.68e-05749115int:H3-3A
InteractionCENPV interactions

RBM19 CHD3 FBXW7

3.36e-05121113int:CENPV
InteractionCHD4 interactions

RBM19 CHD3 CHD5 NOL4 FBXW7

7.89e-05938115int:CHD4
InteractionNUMA1 interactions

CHD3 ATAD2 BRPF1 FBXW7

8.39e-05469114int:NUMA1
InteractionFBP2 interactions

CHD3 FBXW7

8.74e-0526112int:FBP2
InteractionDDX23 interactions

RBM19 CHD3 BRPF1 FBXW7

9.18e-05480114int:DDX23
InteractionRCOR1 interactions

CHD3 PPP6R1 NOL4 FBXW7

1.03e-04494114int:RCOR1
InteractionDDX10 interactions

RBM19 CHD3 FBXW7

1.29e-04190113int:DDX10
InteractionARID4B interactions

CHD3 CHD5 FBXW7

1.48e-04199113int:ARID4B
InteractionUSP20 interactions

BRPF1 SEC62 FBXW7

1.63e-04206113int:USP20
InteractionSGPL1 interactions

PPP6R1 SEC62 FBXW7

1.80e-04213113int:SGPL1
InteractionJAG1 interactions

SEC62 FBXW7

2.20e-0441112int:JAG1
InteractionMBD3L2 interactions

CHD3 CHD5

2.20e-0441112int:MBD3L2
InteractionBRSK1 interactions

PPP6R1 FBXW7

2.30e-0442112int:BRSK1
InteractionGPATCH4 interactions

RBM19 CHD3 FBXW7

2.32e-04232113int:GPATCH4
InteractionDCLRE1C interactions

PPP6R1 FBXW7

2.42e-0443112int:DCLRE1C
InteractionCDK2AP2 interactions

CHD3 CHD5

3.14e-0449112int:CDK2AP2
InteractionKNOP1 interactions

RBM19 CHD3 FBXW7

3.70e-04272113int:KNOP1
InteractionHNRNPCL2 interactions

RBM19 CHD3 ATAD2

3.78e-04274113int:HNRNPCL2
InteractionRAD51B interactions

CHD3 CHD5

3.96e-0455112int:RAD51B
InteractionADAR interactions

CHD3 CHD5 FBXW7

4.29e-04286113int:ADAR
InteractionMRE11 interactions

CHD3 SEC62 FBXW7

4.33e-04287113int:MRE11
InteractionNAT10 interactions

RBM19 CHD3 FBXW7

5.03e-04302113int:NAT10
InteractionZKSCAN1 interactions

CHD3 FBXW7

5.70e-0466112int:ZKSCAN1
InteractionRRP12 interactions

RBM19 CHD3 FBXW7

5.95e-04320113int:RRP12
InteractionTSR1 interactions

RBM19 CHD3 FBXW7

6.06e-04322113int:TSR1
InteractionEBNA1BP2 interactions

RBM19 CHD3 FBXW7

6.17e-04324113int:EBNA1BP2
InteractionMBD3L1 interactions

CHD3 CHD5

6.41e-0470112int:MBD3L1
InteractionCHD6 interactions

CHD3 FBXW7

6.59e-0471112int:CHD6
InteractionBCL11B interactions

CHD3 CHD5

7.16e-0474112int:BCL11B
InteractionBRD1 interactions

CHD3 BRPF1 CHD5

7.35e-04344113int:BRD1
InteractionPHF20L1 interactions

CHD3 FBXW7

7.35e-0475112int:PHF20L1
InteractionPWWP2A interactions

CHD3 CHD5

7.55e-0476112int:PWWP2A
InteractionCHD5 interactions

CHD3 CHD5

7.75e-0477112int:CHD5
Cytoband17p13.1

CHD3 PIK3R5

3.55e-0411811217p13.1
CytobandEnsembl 112 genes in cytogenetic band chr17p13

CHD3 PIK3R5

2.98e-03346112chr17p13
GeneFamilyPHD finger proteins

CHD3 BRPF1 CHD5

6.56e-06908388
GeneFamilyPHD finger proteins|NuRD complex

CHD3 CHD5

1.13e-0512821305
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

CHD3 CHD5 NOL4

1.37e-0519911377b4aa00f14b86ef5db0490be98787e063979541
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Lancl3_(Cortical_Subplate_pyramidal_cells)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SEC62 PIK3R5

2.06e-04881127838c65160cf81c02b923fc34f566c0610c8d81b
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Lancl3_(Cortical_Subplate_pyramidal_cells)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SEC62 PIK3R5

2.06e-0488112fcc15c5c30517c63a835b28627c5f779d9bcd17e
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RBM19 BRPF1

3.69e-041181123b077ad5c68c01b3fcc93f203cb130bb90705af9
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RBM19 BRPF1

3.69e-0411811208bdf7bc3c9dcbc0f690658fe14e6cc4b9581698
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD5 NOL4

6.35e-04155112498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 CHD5

6.35e-0415511272a19a9ecfd13f6769c4b447d3ce01a855ec6ec7
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM19 PIK3R5

6.77e-04160112296e53e1e0786346d38db2d4188b9a1c0430627b
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM19 PIK3R5

6.77e-0416011255f599df6e3b7a5a505df4b094c834281311d94a
ToppCellfacs-Lung-EPCAM-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRPF1 PIK3R5

6.94e-04162112484ea4ac40de672dcbd2583a52cb7f385c918814
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRPF1 PIK3R5

6.94e-04162112bba144ac5332bab9eba2ccf599703c781a7f88f1
ToppCellfacs-BAT-Fat-18m-Lymphocytic-NK_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 PIK3R5

7.11e-04164112ab9c17f86b98e1a4d5db1bd3086edab1320ebda8
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATAD2 PIK3R5

7.19e-041651125f606959a060b1ae241217889560c6761ac73bbb
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATAD2 CHD5

7.46e-04168112a1755afa2cc50960ba60e07d84d61be429cdea72
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ATAD2 PPP6R1

7.54e-04169112c6e5b179461996ced6c7621dc01cec00d401f4e8
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ATAD2 PPP6R1

7.54e-04169112ea600c63cf9572bc4b3cad6392f67bd0d92c7fc9
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CHD5 NOL4

7.54e-0416911296a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATAD2 CHD5

7.99e-0417411265147b0f8c2ccadd5685430d31081520c157536a
ToppCellClub-club-15|World / Class top

ATAD2 FBXW7

8.09e-04175112ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BRPF1 PIK3R5

8.18e-041761128488997e0f02e874f53fae1690da63e0dd1d0780
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATAD2 PIK3R5

8.18e-04176112270d7908dbd84028958d257f94941dc685e20255
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEC62 FBXW7

8.83e-04183112cf5c98f451a568308c52da5c926543dd4836c6b2
ToppCellILEUM-inflamed-(5)_IgA_plasma_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SEC62 FBXW7

8.83e-04183112a113558ca4220bac31f9336033dff82a618d9258
ToppCell10x5'-GI_large-bowel-Lymphocytic_B_plasma|GI_large-bowel / Manually curated celltypes from each tissue

SEC62 FBXW7

9.03e-04185112989583c487d8c121e3731faf68f863ba43a582e6
ToppCell10x5'-GI_large-bowel-Lymphocytic_B_plasma-Plasma_cells|GI_large-bowel / Manually curated celltypes from each tissue

SEC62 FBXW7

9.03e-041851122cad994207c4afc9d70f4c2d243ffbbcdbba693e
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 CHD5

9.12e-041861127278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellILEUM-inflamed-(5)_Plasma|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SEC62 FBXW7

9.12e-041861124d105437487bf04f8cd6129b822d5c060af0bee8
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 CHD5

9.22e-041871122f153b203fe79f206319603cf94d3a03ab49a05d
ToppCellCerebellum-Neuronal|Cerebellum / BrainAtlas - Mouse McCarroll V32

CHD5 NOL4

9.22e-0418711261b9d6eb131a674598aa8409d7fa909c8765442d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 CHD5

9.22e-04187112e04a84989d624378141042768383b9c846901f2d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD2 PIK3R5

9.22e-0418711273931a5ea73799095daff100b5f18853c57c74dc
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 CHD5

9.22e-0418711224cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_regulatory_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CHD3 PPP6R1

9.82e-0419311228138c35ea82c6b2163f0cae045ca55859347c73
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD5 NOL4

9.82e-04193112a189d46c39067b717509cd144e0225cc93d7731d
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)|356C / Donor, Lineage, Cell class and subclass (all cells)

RBM19 BRPF1

9.92e-0419411299a90de637e3babec2131cdd9f05ea965d8a8f30
ToppCellCV-Severe-6|Severe / Virus stimulation, Condition and Cluster

CHD3 SEC62

9.92e-04194112d33be6ed1de907aeea0c2dce09796556b8efdd4e
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEC62 FBXW7

9.92e-04194112f083777353e76a2d9c39f8b6cb1a689b68b81c56
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)-|356C / Donor, Lineage, Cell class and subclass (all cells)

RBM19 BRPF1

9.92e-041941124c40d6b50675eae52c419d69e719a9223df02ae3
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ATAD2 SEC62

9.92e-0419411240c6e17e9e48d4fa6da3a0a1066c4c6565a1e096
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CHD5 NOL4

1.01e-031961124bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ATAD2 PPP6R1

1.01e-0319611236ed1918f70b6f5760bb088b15ce422998055cc7
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Neuronal-CPNs|6_mon / Sample Type, Dataset, Time_group, and Cell type.

CHD5 FBXW7

1.01e-03196112c9e7ac34993c873de4f198cdae77dcf099731532
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-cortical_neurons_1|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

CHD3 NOL4

1.03e-03198112d81f35c0066558ff96dd06f58fca72cd82e681e8
ToppCellTransverse-(2)_B_cell-(21)_B_cell_IgG_Plasma|Transverse / shred on region, Cell_type, and subtype

SEC62 FBXW7

1.03e-03198112d6052b5a44246798e90f4779cd940ffac7539fcd
ToppCellTransverse-B_cell-B_cell_IgG_Plasma|Transverse / Region, Cell class and subclass

SEC62 FBXW7

1.03e-03198112a4ece1fe3d15acfde0e6ff14cddb3a3d16f61ce0
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHD5 FBXW7

1.03e-031981128ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellTransverse-B_cell-B_cell_IgA_Plasma|Transverse / Region, Cell class and subclass

SEC62 FBXW7

1.04e-03199112ea65cadaf464ff4c1040fceb5f3724706f8447c1
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

CHD3 CHD5

1.04e-031991121b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellSigmoid-(2)_B_cell|Sigmoid / shred on region, Cell_type, and subtype

SEC62 FBXW7

1.04e-03199112646960845ede4c5b00cdfe73051d5d4577648bf8
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

CHD5 NOL4

1.04e-031991125de2a32bc2e9c752eb19a013b1807949153728fc
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

CHD3 CHD5

1.04e-031991124bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellSigmoid-B_cell|Sigmoid / Region, Cell class and subclass

SEC62 FBXW7

1.04e-03199112997ee1b622b1e349d5e98026afbc4f8d283b2136
ToppCellSigmoid-B_cell-B_cell_IgA_Plasma|Sigmoid / Region, Cell class and subclass

SEC62 FBXW7

1.04e-03199112634e0b614ab45e7520da67375b3498db5442b7ae
ToppCellSigmoid-(2)_B_cell-(20)_B_cell_IgA_Plasma|Sigmoid / shred on region, Cell_type, and subtype

SEC62 FBXW7

1.04e-03199112f3c583f8521f63834d1afbf8b07940fee7712f9a
ToppCellNeuron-Postmitotic-Excitatory_Neuron_|World / Primary Cells by Cluster

CHD3 FBXW7

1.04e-03199112058373b4ac3cec2108cb24265628ff0a50646e33
ToppCellTransverse-(2)_B_cell-(20)_B_cell_IgA_Plasma|Transverse / shred on region, Cell_type, and subtype

SEC62 FBXW7

1.04e-031991128caaa08b046f766af298d03961ccac6e4569e2a6
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal|10w / Sample Type, Dataset, Time_group, and Cell type.

CHD3 CHD5

1.05e-03200112979258173b82f37aeaaedd53b4a527da1dbe1b80
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Cortical_neuron|3m / Sample Type, Dataset, Time_group, and Cell type.

CHD3 NOL4

1.05e-03200112c248233b004f8ef0bab3c65ecfe295887966f2ee
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-cortical_neurons_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

CHD3 NOL4

1.05e-032001120cb0755a101ec655359d051d6a8807408d727c55
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal|3m / Sample Type, Dataset, Time_group, and Cell type.

CHD3 NOL4

1.05e-03200112af99d90070e2933fd2e9512590c6cf3bd6e15539
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

CHD3 NOL4

1.05e-03200112e4f0bb57be1112869c7068d0a789c2b802a442dd
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Cortical_neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

CHD3 CHD5

1.05e-0320011268c90376e2779434e4ad8dc6dd3b44baa700e2f4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Interneuron|2m / Sample Type, Dataset, Time_group, and Cell type.

CHD5 NOL4

1.05e-0320011208bee924a2654e05df3b39e8a51f93c8b3472175
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal|6m / Sample Type, Dataset, Time_group, and Cell type.

CHD5 NOL4

1.05e-03200112cedbc47b1defb5973cf7ab6baaa2d6f2fd481f88
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Cortical_neuron|6m / Sample Type, Dataset, Time_group, and Cell type.

CHD5 NOL4

1.05e-032001126f7ff0533339fcc9d316f2c77334a79c1409ec4f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

CHD5 FBXW7

1.05e-032001125c7263c862093ad9dbc81d06b16b6f74e8a6b634
DrugPyrantel tartrate [33401-94-4]; Down 200; 11.2uM; HL60; HG-U133A

RBM19 CHD3 PPP6R1

9.27e-051921131413_DN
DrugIsocarboxazid [59-63-2]; Down 200; 17.2uM; MCF7; HT_HG-U133A

RBM19 CHD3 FBXW7

9.70e-051951134706_DN
DrugBenzonatate [104-31-4]; Down 200; 6.6uM; MCF7; HT_HG-U133A

RBM19 CHD3 BRPF1

9.85e-051961131679_DN
DrugAdamantamine fumarate [80789-67-9]; Up 200; 9.6uM; HL60; HT_HG-U133A

RBM19 CHD3 BRPF1

9.85e-051961131344_UP
DrugPantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; MCF7; HT_HG-U133A

CHD3 BRPF1 PPP6R1

9.85e-051961133248_DN
DrugSulfasalazine [599-79-1]; Up 200; 10uM; HL60; HG-U133A

CHD3 BRPF1 FBXW7

1.02e-041981131733_UP
DrugMimosine [500-44-7]; Down 200; 20.2uM; MCF7; HT_HG-U133A

CHD3 BRPF1 FBXW7

1.03e-041991135302_DN
DrugTrolox [53188-07-1]; Down 200; 16uM; MCF7; HT_HG-U133A

RBM19 CHD3 FBXW7

1.03e-041991132883_DN
DrugIdoxuridine [54-42-2]; Up 200; 11.2uM; HL60; HG-U133A

CHD3 ATAD2 FBXW7

1.05e-042001131980_UP
DiseaseColorectal Carcinoma

CHD5 FERD3L PIK3R5 FBXW7

9.17e-05702114C0009402
Diseaseasthma, response to diisocyanate

NOL4 FERD3L

4.07e-03261112EFO_0006995, MONDO_0004979
Disease3-hydroxypropylmercapturic acid measurement

NOL4 PIK3R5

7.27e-03352112EFO_0007014

Protein segments in the cluster

PeptideGeneStartEntry
DEEEEGGCEEEEDDH

CHD5

401

Q8TDI0
EEGEDQEHEDDGEDE

ATAD2

246

Q6PL18
DEAVHCDEGSEAEEE

RBM19

231

Q9Y4C8
ECEVDQGDGEEEEEE

FERD3L

66

Q96RJ6
EEGEEEGEKEEEDDH

CHD3

441

Q12873
DEEHAGEQDEEDEEE

FBXW7

101

Q969H0
GDEDEDDHEDHDDSE

NOL4

381

O94818
HSEGEEDEDEEEDEG

BRPF1

461

P55201
DGDCEEDEEEENDGE

SEC62

376

Q99442
EEEEVEEDLETDGHC

PIK3R5

326

Q8WYR1
EDEEEEEDEEGIGCA

PPP6R1

676

Q9UPN7