Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glycolipid mannosyltransferase activity	PIGB PIGM	1.42e-04	5	76	2	GO:0004376
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ATP8B3 ABCA4 ATP10A	1.62e-04	28	76	3	GO:0140326
HumanPheno	Perifollicular hyperkeratosis	KRT81 KRT83 KRT86	8.13e-07	4	31	3	HP:0007468
HumanPheno	Abnormal perifollicular morphology	KRT81 KRT83 KRT86	4.03e-06	6	31	3	HP:0031285
Domain	NDUF_C2	NDUFC2-KCTD14 NDUFC2	1.63e-05	2	76	2	PF06374
Domain	NADH-UbQ_OxRdtase_b14.5b_su	NDUFC2-KCTD14 NDUFC2	1.63e-05	2	76	2	IPR009423
Domain	GRAM	GRAMD1B SBF1 GRAMD1A	3.49e-05	16	76	3	SM00568
Domain	VAST	GRAMD1B GRAMD1A	4.89e-05	3	76	2	PS51778
Domain	DUF4782	GRAMD1B GRAMD1A	4.89e-05	3	76	2	IPR031968
Domain	DUF4782	GRAMD1B GRAMD1A	4.89e-05	3	76	2	PF16016
Domain	Ez/rad/moesin-like	MYLIP EPB41L1 EPB41L2	8.17e-05	21	76	3	IPR000798
Domain	GRAM	GRAMD1B SBF1 GRAMD1A	9.43e-05	22	76	3	PF02893
Domain	GRAM	GRAMD1B SBF1 GRAMD1A	9.43e-05	22	76	3	IPR004182
Domain	Band_4.1_C	EPB41L1 EPB41L2	9.75e-05	4	76	2	IPR008379
Domain	4_1_CTD	EPB41L1 EPB41L2	9.75e-05	4	76	2	PF05902
Domain	SAB_dom	EPB41L1 EPB41L2	9.75e-05	4	76	2	IPR007477
Domain	SAB	EPB41L1 EPB41L2	9.75e-05	4	76	2	PF04382
Domain	Keratin_2_head	KRT81 KRT83 KRT86	1.23e-04	24	76	3	IPR032444
Domain	Keratin_2_head	KRT81 KRT83 KRT86	1.23e-04	24	76	3	PF16208
Domain	FERM_C	MYLIP EPB41L1 EPB41L2	1.57e-04	26	76	3	PF09380
Domain	Keratin_II	KRT81 KRT83 KRT86	1.57e-04	26	76	3	IPR003054
Domain	FERM_C	MYLIP EPB41L1 EPB41L2	1.77e-04	27	76	3	SM01196
Domain	FERM_PH-like_C	MYLIP EPB41L1 EPB41L2	1.77e-04	27	76	3	IPR018980
Domain	FERM_N	MYLIP EPB41L1 EPB41L2	3.24e-04	33	76	3	PF09379
Domain	FERM_N	MYLIP EPB41L1 EPB41L2	3.24e-04	33	76	3	IPR018979
Domain	Hydrolase_3	ATP8B3 ATP10A	7.20e-04	10	76	2	PF08282
Domain	FERM_M	MYLIP EPB41L1 EPB41L2	8.67e-04	46	76	3	PF00373
Domain	-	MYLIP EPB41L1 EPB41L2	1.04e-03	49	76	3	1.20.80.10
Domain	FERM_central	MYLIP EPB41L1 EPB41L2	1.04e-03	49	76	3	IPR019748
Domain	FERM_domain	MYLIP EPB41L1 EPB41L2	1.04e-03	49	76	3	IPR000299
Domain	-	SBF1 MYLIP OBSCN FGD1 PLEKHM1 EPB41L1 EPB41L2	1.06e-03	391	76	7	2.30.29.30
Domain	FERM_1	MYLIP EPB41L1 EPB41L2	1.11e-03	50	76	3	PS00660
Domain	FERM_2	MYLIP EPB41L1 EPB41L2	1.11e-03	50	76	3	PS00661
Domain	FERM_3	MYLIP EPB41L1 EPB41L2	1.11e-03	50	76	3	PS50057
Domain	Band_41_domain	MYLIP EPB41L1 EPB41L2	1.11e-03	50	76	3	IPR019749
Domain	B41	MYLIP EPB41L1 EPB41L2	1.11e-03	50	76	3	SM00295
Domain	FERM/acyl-CoA-bd_prot_3-hlx	MYLIP EPB41L1 EPB41L2	1.11e-03	50	76	3	IPR014352
Domain	FERM-adjacent	EPB41L1 EPB41L2	1.24e-03	13	76	2	IPR014847
Domain	FA	EPB41L1 EPB41L2	1.24e-03	13	76	2	SM01195
Domain	FA	EPB41L1 EPB41L2	1.24e-03	13	76	2	PF08736
Domain	Dynein_HC_stalk	DNHD1 DNAH9	1.44e-03	14	76	2	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH9	1.44e-03	14	76	2	IPR013602
Domain	DHC_N2	DNHD1 DNAH9	1.44e-03	14	76	2	PF08393
Domain	MT	DNHD1 DNAH9	1.44e-03	14	76	2	PF12777
Domain	P_typ_ATPase_c	ATP8B3 ATP10A	1.44e-03	14	76	2	IPR032630
Domain	P-type_ATPase_N	ATP8B3 ATP10A	1.44e-03	14	76	2	IPR032631
Domain	P-type_ATPase_IV	ATP8B3 ATP10A	1.44e-03	14	76	2	IPR006539
Domain	PhoLip_ATPase_C	ATP8B3 ATP10A	1.44e-03	14	76	2	PF16212
Domain	PhoLip_ATPase_N	ATP8B3 ATP10A	1.44e-03	14	76	2	PF16209
Domain	DHC_fam	DNHD1 DNAH9	1.66e-03	15	76	2	IPR026983
Domain	Dynein_heavy_dom	DNHD1 DNAH9	1.66e-03	15	76	2	IPR004273
Domain	Dynein_heavy	DNHD1 DNAH9	1.66e-03	15	76	2	PF03028
Domain	PH_dom-like	SBF1 MYLIP OBSCN FGD1 PLEKHM1 EPB41L1 EPB41L2	1.73e-03	426	76	7	IPR011993
Domain	Intermediate_filament_CS	KRT81 KRT83 KRT86	2.16e-03	63	76	3	IPR018039
Domain	Filament	KRT81 KRT83 KRT86	3.03e-03	71	76	3	SM01391
Domain	IF	KRT81 KRT83 KRT86	3.16e-03	72	76	3	PS00226
Domain	Filament	KRT81 KRT83 KRT86	3.28e-03	73	76	3	PF00038
Domain	IF	KRT81 KRT83 KRT86	3.68e-03	76	76	3	IPR001664
Pubmed	Structure and site of expression of a murine type II hair keratin.	KRT81 KRT83 KRT86	1.09e-08	3	78	3	1372089
Pubmed	Transient expression of mouse hair keratins in transfected HeLa cells: interactions between "hard" and "soft" keratins.	KRT81 KRT83 KRT86	1.09e-08	3	78	3	1712823
Pubmed	Novel KRT83 and KRT86 mutations associated with monilethrix.	KRT81 KRT83 KRT86	1.09e-08	3	78	3	25557232
Pubmed	Keratins of the human hair follicle.	KRT81 KRT83 KRT86	4.33e-08	4	78	3	15797458
Pubmed	Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain.	KRT81 KRT83 KRT86	2.35e-06	12	78	3	10692104
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GRAMD1B NDUFC2-KCTD14 PDE2A SBF1 PLXNA4 FARSB SAMM50 TRAPPC3 ARID1A NDUFC2 NCDN EPB41L1 EPB41L2 IQGAP1	3.25e-06	1431	78	14	37142655
Pubmed	A missense mutation in the type II hair keratin hHb3 is associated with monilethrix.	KRT83 KRT86	4.97e-06	2	78	2	15744029
Pubmed	The function of glutamatergic synapses is not perturbed by severe knockdown of 4.1N and 4.1G expression.	EPB41L1 EPB41L2	4.97e-06	2	78	2	19225127
Pubmed	A variable monilethrix phenotype associated with a novel mutation, Glu402Lys, in the helix termination motif of the type II hair keratin hHb1.	KRT81 KRT86	4.97e-06	2	78	2	9665406
Pubmed	NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.	NDUFC2-KCTD14 NDUFC2	4.97e-06	2	78	2	37506315
Pubmed	A new mutation in the type II hair cortex keratin hHb1 involved in the inherited hair disorder monilethrix.	KRT81 KRT86	4.97e-06	2	78	2	9402962
Pubmed	Aster Proteins Regulate the Accessible Cholesterol Pool in the Plasma Membrane.	GRAMD1B GRAMD1A	4.97e-06	2	78	2	32719109
Pubmed	Comprehensive analysis of keratin gene clusters in humans and rodents.	KRT81 KRT83 KRT86	5.95e-06	16	78	3	15085952
Pubmed	PERP regulates enamel formation via effects on cell-cell adhesion and gene expression.	KRT81 KRT83 KRT86	1.02e-05	19	78	3	21285247
Pubmed	Regulation of AMPA receptor GluR1 subunit surface expression by a 4. 1N-linked actin cytoskeletal association.	EPB41L1 EPB41L2	1.49e-05	3	78	2	11050113
Pubmed	Function of a membrane-embedded domain evolutionarily multiplied in the GPI lipid anchor pathway proteins PIG-B, PIG-M, PIG-U, PIG-W, PIG-V, and PIG-Z.	PIGB PIGM	1.49e-05	3	78	2	29764287
Pubmed	Sequence data and chromosomal localization of human type I and type II hair keratin genes.	KRT81 KRT86	1.49e-05	3	78	2	7556444
Pubmed	Sequences and differential expression of three novel human type-II hair keratins.	KRT83 KRT86	1.49e-05	3	78	2	9084137
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	UBR2 CNNM4 NACC2 ABCC8 ASH1L OBSCN SAMM50 ZMIZ1 ARID1A ATP10A PLEKHM1 NCDN EPB41L1	2.54e-05	1489	78	13	28611215
Pubmed	TEAD1, MYO7A and NDUFC2 are novel functional genes associated with glucose metabolism in BXD recombinant inbred population.	NDUFC2-KCTD14 NDUFC2	2.97e-05	4	78	2	38385898
Pubmed	Characterization and chromosomal localization of human hair-specific keratin genes and comparative expression during the hair growth cycle.	KRT81 KRT86	2.97e-05	4	78	2	9457912
Pubmed	Cardiac muscle cell cytoskeletal protein 4.1: analysis of transcripts and subcellular location--relevance to membrane integrity, microstructure, and possible role in heart failure.	EPB41L1 EPB41L2	2.97e-05	4	78	2	15834631
Pubmed	Hnrnpk maintains chondrocytes survival and function during growth plate development via regulating Hif1α-glycolysis axis.	NDUFC2-KCTD14 IHH NDUFC2	4.66e-05	31	78	3	36127325
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	CNNM4 EMC1 EXD2 GRAMD1A FARSB SAMM50 TRAPPC3 NCDN LCLAT1 IQGAP1	4.82e-05	942	78	10	31073040
Pubmed	Band 4.1 proteins regulate integrin-dependent cell spreading.	EPB41L1 EPB41L2	4.94e-05	5	78	2	22982319
Pubmed	Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells.	GRAMD1B GRAMD1A	7.40e-05	6	78	2	30220461
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	UBR2 DNAH9 PLEKHM1 EPB41L1	9.08e-05	104	78	4	9205841
Pubmed	D2 and D3 dopamine receptor cell surface localization mediated by interaction with protein 4.1N.	EPB41L1 EPB41L2	1.04e-04	7	78	2	12181426
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EMC1 SBF1 RBBP5 CNOT10 EXD2 RCL1 FARSB FAM91A1 ICE1 EPB41L1 EPB41L2 IQGAP1	1.21e-04	1497	78	12	31527615
Pubmed	Energy deprivation and a deficiency in downstream metabolic target genes during the onset of embryonic heart failure in RXRalpha-/- embryos.	NDUFC2-KCTD14 NDUFC2	1.38e-04	8	78	2	9425147
Pubmed	Structural diversity of band 4.1 superfamily members.	EPB41L1 EPB41L2	1.38e-04	8	78	2	7983158
Pubmed	Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.	MYLIP EPB41L2	2.21e-04	10	78	2	22331829
Pubmed	Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.	RBBP5 CNOT10 ARID1A	3.22e-04	59	78	3	28813667
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	KRT81 KRT83 KRT86 UBASH3A IQGAP1	3.38e-04	266	78	5	19380743
Pubmed	Differential expression of putative transbilayer amphipath transporters.	ATP8B3 ATP10A	3.81e-04	13	78	2	11015572
Pubmed	New consensus nomenclature for mammalian keratins.	KRT81 KRT83 KRT86	3.91e-04	63	78	3	16831889
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	BTC KRT81 KRT83 KRT86 ICE1	4.55e-04	284	78	5	29459677
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TUBGCP6 GRAMD1B EMC1 SBF1 GRAMD1A RCL1 SAMM50 NCDN ATPAF1 EPB41L1 EPB41L2	4.71e-04	1487	78	11	33957083
Pubmed	DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis.	KRT81 KRT83 KRT86	5.33e-04	70	78	3	34255829
Pubmed	Hague (Hag). A new mouse hair mutation with an unstable semidominant allele.	KRT81 KRT86	5.84e-04	16	78	2	12399393
Pubmed	Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis.	PIGB PIGM	6.61e-04	17	78	2	11102867
Pubmed	Proteomic analysis of the mouse liver mitochondrial inner membrane.	NDUFC2-KCTD14 CYP27A1 SAMM50 NDUFC2	6.61e-04	175	78	4	12865426
Pubmed	Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions.	NDUFC2-KCTD14 SAMM50 NDUFC2 EPB41L2	6.75e-04	176	78	4	18614564
Pubmed	Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.	AMT EMC1 OBSCN PLXNA4 NDUFC2 ATPAF1 PARS2 IQGAP1	6.85e-04	859	78	8	31536960
Pubmed	Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.	PDE2A CSF2	7.42e-04	18	78	2	22446963
Pubmed	The protein interactome of collapsin response mediator protein-2 (CRMP2/DPYSL2) reveals novel partner proteins in brain tissue.	NDUFC2-KCTD14 PDE2A NDUFC2	7.59e-04	79	78	3	25921334
Pubmed	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	HLA-F ZMIZ1	8.28e-04	19	78	2	19525953
Pubmed	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	CNNM4 ZMIZ1	8.28e-04	19	78	2	18711365
Pubmed	Cancer Stem Cells Regulate Cancer-Associated Fibroblasts via Activation of Hedgehog Signaling in Mammary Gland Tumors.	CSF2 IHH	8.28e-04	19	78	2	28202523
Pubmed	Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis.	KRT81 KRT86	8.28e-04	19	78	2	27234308
Pubmed	Four paralogous protein 4.1 genes map to distinct chromosomes in mouse and human.	EPB41L1 EPB41L2	9.19e-04	20	78	2	9828140
Pubmed	Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.	UBR2 LONRF1 MYLIP	9.39e-04	85	78	3	19028597
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	CNOT10 ABCC8 GRAMD1A HLA-F ASH1L EPB41L1 PIGM	9.72e-04	697	78	7	28298427
Pubmed	Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.	UBR2 CNNM4 SBF1 CNOT10 RCL1 FAM91A1 SAMM50 NCDN	1.15e-03	931	78	8	27432908
Pubmed	Contribution of calumin to embryogenesis through participation in the endoplasmic reticulum-associated degradation activity.	EMC1 IHH	1.33e-03	24	78	2	25009997
Pubmed	Vegf regulates embryonic erythroid development through Gata1 modulation.	LMO2 IHH	1.33e-03	24	78	2	20554972
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	RBBP5 EXOC3L4 OBSCN PLXNA4 ICE1 EPB41L2 PIGM	1.33e-03	736	78	7	29676528
Pubmed	Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.	KRT81 KRT83 KRT86	1.33e-03	96	78	3	23580065
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	GRAMD1B CNNM4 EMC1 RBBP5 GRAMD1A FARSB SAMM50 TRAPPC3 LCLAT1 IQGAP1	1.40e-03	1440	78	10	30833792
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	PDE2A SBF1 FARSB TRAPPC3 NCDN EPB41L1 EPB41L2 IQGAP1	1.42e-03	963	78	8	28671696
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	NDUFC2-KCTD14 EMC1 SBF1 HLA-F ARID1A NDUFC2 EPB41L1 LCLAT1 EPB41L2 IQGAP1	1.48e-03	1451	78	10	30550785
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	CNNM4 OBSCN PLXNA4	1.54e-03	101	78	3	10997877
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	RBBP5 CNOT10 FAM91A1 NCDN EPB41L2 IQGAP1	1.64e-03	560	78	6	35241646
Pubmed	The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.	SBF1 LONRF1 EPB41L1 EPB41L2	1.67e-03	225	78	4	25277244
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	ZNF430 OBSCN DNAH9 EPB41L2	1.70e-03	226	78	4	31452512
Pubmed	The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes.	NDUFC2-KCTD14 OBSCN SAMM50 NDUFC2 ATPAF1	1.71e-03	382	78	5	29222160
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	TBC1D12 ATP10A NCDN	1.73e-03	105	78	3	9628581
Pubmed	Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy.	PDE2A EMC1 SAMM50	1.77e-03	106	78	3	33087821
Cytoband	12q13	KRT81 KRT83 KRT86	2.48e-04	71	78	3	12q13
GeneFamily	Erythrocyte membrane protein band 4.1\|FERM domain containing	EPB41L1 EPB41L2	4.48e-05	4	50	2	951
GeneFamily	Keratins, type II	KRT81 KRT83 KRT86	5.56e-05	27	50	3	609
GeneFamily	Dolichyl D-mannosyl phosphate dependent mannosyltransferases\|Phosphatidylinositol glycan anchor biosynthesis	PIGB PIGM	2.67e-04	9	50	2	430
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	MYLIP EPB41L1 EPB41L2	3.56e-04	50	50	3	1293
GeneFamily	WD repeat domain containing\|GRAM domain containing\|BEACH domain containing	GRAMD1B GRAMD1A	5.73e-04	13	50	2	1146
GeneFamily	ATPase phospholipid transporting	ATP8B3 ATP10A	7.69e-04	15	50	2	1210
GeneFamily	Aminoacyl tRNA synthetases, Class II	FARSB PARS2	1.24e-03	19	50	2	132
GeneFamily	Glycosyl transferases group 1 domain containing\|Phosphatidylinositol glycan anchor biosynthesis	PIGB PIGM	1.52e-03	21	50	2	680
Coexpression	GSE25677_MPL_VS_R848_STIM_BCELL_DN	PDE2A LMO2 TENT5A GRAMD1A MYLIP ICE1 IQGAP1	1.17e-06	181	78	7	M8187
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_pDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MYBPH KRT81 KRT86 PLXNA4 ATP10A EPB41L1	4.92e-07	167	78	6	8ddf9da71a7c4ed53588435db826563a24cee616
ToppCell	IPF-Lymphoid-ILC_B\|Lymphoid / Disease state, Lineage and Cell class	KRT81 KRT86 PLXNA4 ZMIZ1 IHH ATP10A	8.40e-07	183	78	6	9b507547e6adf78e46e7f542cd9958224ec5826a
ToppCell	PCW_07-8.5-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_natural_killer_[NK]_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CSF2 SNX20 KRT81 KRT86 HLA-F UBASH3A	1.05e-06	190	78	6	5c6801046ab88aad76697984342319872a8f9e38
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-NK\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TUBGCP6 CSF2 KRT81 KRT86 MYLIP UBAP1L	1.11e-06	192	78	6	930319cbd82b9e54864147ffcdc8bd0ea7b937be
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TUBGCP6 CSF2 KRT81 KRT86 MYLIP UBAP1L	1.11e-06	192	78	6	c7bcebcb88a25b2c97d798120efa9d5958e7f798
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	LMO2 TBC1D12 PLXNA4 ZMIZ1 EPB41L2	1.19e-05	169	78	5	a0681317867e31319210a23e56660a53f4529efe
ToppCell	COPD-Lymphoid-ILC_A\|Lymphoid / Disease state, Lineage and Cell class	CSF2 KRT81 KRT83 KRT86 PLXNA4	1.33e-05	173	78	5	4a0043b29f8ede5a74bdb38cbf2c70e12b25e130
ToppCell	wk_20-22-Hematologic_Lymphocytic-T_&_ILC-ILCP\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GRAMD1B SNX20 KRT81 KRT86 ATP10A	1.37e-05	174	78	5	5e6050d20a5b27640f6a200441125b8ceba123c8
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILCP\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GRAMD1B CSF2 SNX20 KRT81 KRT86	1.45e-05	176	78	5	238244294d08975df6bfa26b2b437db3654408ae
ToppCell	3'-GW_trimst-1-LargeIntestine-Hematopoietic-T_cells-ILCP\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GRAMD1B SNX20 KRT81 KRT83 KRT86	1.57e-05	179	78	5	dd3cf8fd10dc257d933a7f45860dc2e244c158b7
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-SELL+_CD4_T\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP8B3 SNX20 KRT81 HLA-F UBASH3A	1.62e-05	180	78	5	702673c0b7c5b0d22a6af3884374804b8c4d6254
ToppCell	mild_COVID-19_(asymptomatic)-cDC\|World / disease group, cell group and cell class (v2)	LMO2 TBC1D12 ZMIZ1 EPB41L1 EPB41L2	1.62e-05	180	78	5	68d1c867734fb2977b01ac686b20bf602f9a6b72
ToppCell	wk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILCP\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	GRAMD1B KRT81 KRT83 KRT86 ATP10A	1.70e-05	182	78	5	6bd48c5d60a259719f65cacee4b8135247e78fa9
ToppCell	wk_08-11-Hematologic_Lymphocytic-T_&_ILC-ILCP\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SNX20 KRT81 KRT83 KRT86 UBASH3A	1.75e-05	183	78	5	797eb968c57e48db33ff8e2236ee22e9425c4676
ToppCell	PCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC3_(12)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CSF2 KRT81 KRT86 UBASH3A ATP10A	1.80e-05	184	78	5	3e9d75af578297950e469f23fb2d28393a2feef8
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-ILCP\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SNX20 KRT81 KRT83 KRT86 ATP10A	1.84e-05	185	78	5	e1fd66f4295056807aa29c0e4ce6b1a79cc8dfcf
ToppCell	NS-moderate-d_07-13-Lymphoid-NKT\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CSF2 KRT81 KRT83 KRT86 UBASH3A	2.04e-05	189	78	5	24519fa45e7d1c2fb397e9ffe00ecb7f7d4cefd8
ToppCell	PCW_07-8.5-Immune_Lymphocytic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CSF2 SNX20 KRT81 KRT86 UBASH3A	2.15e-05	191	78	5	8911b88f70e5deed027177be2e6745b80308616b
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SNX20 KRT81 KRT83 KRT86 ATP10A	2.43e-05	196	78	5	609959609ab1870c562cefca0fd49e0d701d1e5b
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-ILC\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GRAMD1B CSF2 KRT81 KRT83 KRT86	2.61e-05	199	78	5	3bac69726153e988a7f36613ee280c74d2fa7545
ToppCell	Transverse-T_cell-gd_T\|T_cell / Region, Cell class and subclass	KRT81 KRT86 PLXNA4 ZMIZ1 ATP10A	2.61e-05	199	78	5	8baea162803cea7d72dff5866a0eebfcf2e5dcd6
ToppCell	Sigmoid-ILC\|Sigmoid / Region, Cell class and subclass	CSF2 KRT81 KRT83 KRT86 GRAMD1A	2.68e-05	200	78	5	dfb06821f1019833f5d81f9c93808219b5fef407
ToppCell	Sigmoid-(3)_ILC\|Sigmoid / shred on region, Cell_type, and subtype	CSF2 KRT81 KRT83 KRT86 GRAMD1A	2.68e-05	200	78	5	a7326c43987a5eb4f4f5b48c4252cf4870432e5d
ToppCell	Sigmoid-(3)_ILC-(30)_ILC\|Sigmoid / shred on region, Cell_type, and subtype	CSF2 KRT81 KRT83 KRT86 GRAMD1A	2.68e-05	200	78	5	c39de94623383da7b2b260eb016ddaa5da7f4350
ToppCell	Sigmoid-ILC-ILC\|Sigmoid / Region, Cell class and subclass	CSF2 KRT81 KRT83 KRT86 GRAMD1A	2.68e-05	200	78	5	4ac1e6d7f358003e2448eb69e545772cd261c55f
Drug	Ethosuximide [77-67-8]; Up 200; 28.4uM; PC3; HT_HG-U133A	ATP8B3 CSF2 LMO2 LYPD3 IHH ARID1A ATP10A NCDN	4.27e-07	200	78	8	2116_UP
Drug	tebuquine	KRT81 KRT83	1.16e-05	2	78	2	CID000071991
Drug	3,5-di-O-galloylquinic acid	KRT81 KRT83	1.16e-05	2	78	2	CID000460896
Drug	melicopicine	KRT81 KRT83	1.16e-05	2	78	2	CID000101253
Disease	Beaded hair	KRT81 KRT83 KRT86	1.64e-08	3	76	3	cv:C0546966
Disease	MONILETHRIX	KRT81 KRT83 KRT86	1.64e-08	3	76	3	158000
Disease	monilethrix (is_implicated_in)	KRT81 KRT83 KRT86	1.64e-08	3	76	3	DOID:0050472 (is_implicated_in)
Disease	Monilethrix	KRT81 KRT83 KRT86	6.56e-08	4	76	3	C0546966
Disease	hair disease (is_implicated_in)	KRT81 KRT86	6.55e-06	2	76	2	DOID:421 (is_implicated_in)
Disease	osteoprotegerin measurement	SAMM50 ARID1A	5.84e-04	14	76	2	EFO_0005918
Disease	response to statin, LDL cholesterol change measurement	MYLIP EPB41L2	6.73e-04	15	76	2	EFO_0007804, GO_0036273
Disease	Colorectal Neoplasms	ABCA4 CSF2 ABCC8 ZMIZ1 ARID1A	7.54e-04	277	76	5	C0009404
Disease	phosphatidylcholine 40:6 measurement	SNX20 DNAH9	8.68e-04	17	76	2	EFO_0010389
Disease	hair colour measurement	BTC KRT86 ZMIZ1 ARID1A ATP10A EPB41L1 EPB41L2	1.04e-03	615	76	7	EFO_0007822
Disease	alcohol drinking	LONRF1 PLXNA4 ICE1	1.21e-03	81	76	3	EFO_0004329
Disease	Deep Vein Thrombosis	CSF2 PIGM	1.33e-03	21	76	2	C0149871
Disease	Venous Thrombosis	CSF2 PIGM	1.33e-03	21	76	2	C0042487
Disease	lymphocyte percentage of leukocytes	GRAMD1B UBR2 TENT5A RCL1 ZMIZ1 ARID1A IQGAP1	1.63e-03	665	76	7	EFO_0007993
Disease	Malignant neoplasm of breast	CNNM4 PDE2A ABCA4 CSF2 OBSCN ZMIZ1 KLHDC7A ARID1A DNAH9	1.74e-03	1074	76	9	C0006142
Disease	response to peginterferon alfa-2a	GRAMD1B ATP10A	1.89e-03	25	76	2	EFO_0010103
Disease	inflammatory bowel disease (implicated_via_orthology)	EPB41L1 EPB41L2	1.89e-03	25	76	2	DOID:0050589 (implicated_via_orthology)
Disease	gamma-glutamyltyrosine measurement	ASH1L ZMIZ1	2.20e-03	27	76	2	EFO_0021144
Disease	Colorectal Carcinoma	ABCA4 CSF2 ABCC8 OBSCN ZMIZ1 ARID1A NCDN	2.21e-03	702	76	7	C0009402
Disease	Seizures	PIGB CYP27A1 ZMIZ1 PIGM	2.45e-03	218	76	4	C0036572

Protein segments in the cluster

Peptide	Gene	Start	Entry
LFRTGLGILRLYEDI	TBC1D12	696	O60347
ELARDARGCEQLYIL	EXOC3L4	326	Q17RC7
LLRDDLLLRQGDCVY	ASH1L	2656	Q9NR48
LGDRIAIIAQGRLYC	ABCA4	1126	P78363
GQGLRYLEHLCLVLE	C8orf58	186	Q8NAV2
KYSLDIGNLLLRGCR	ATP8B3	326	O60423
SVRLGYGCLLVLRAL	DNHD1	1796	Q96M86
SCALQREILLQGRLY	GRAMD1A	111	Q96CP6
SCALQRDILLQGRLY	GRAMD1B	116	Q3KR37
GLYKENLLLRGCTLR	ATP10A	256	O60312
EGLITRLQARCRGYL	IQGAP1	746	P46940
RRDYLRLFGQDGLCA	LMO2	81	P25791
GRNCARLLLEEIYRG	RCL1	276	Q9Y2P8
RLLLEEIYRGGCVDS	RCL1	281	Q9Y2P8
LEGECLELLRRYLEN	HLA-F	181	P30511
GLLELLVEYFRRCLI	ARID1A	1711	O14497
YLCLQLRADIITGRL	EPB41L1	191	Q9H4G0
GVCANGLLIYRDRLR	EPB41L1	301	Q9H4G0
VTEALGLCGRYLERQ	KLHL34	111	Q8N239
GLAGRLLLCNYERRV	MYCNOS	56	P40205
ECYRDLQAGLARILG	NCDN	256	Q9UBB6
LAGGLRLLDLSYNRI	LRRC3	111	Q9BY71
LGALVDCLVFNYRLR	LONRF1	86	Q17RB8
YRRLLEGEEQRLCEG	KRT86	406	O43790
ADCLRLLGIGRNQYI	FAM91A1	121	Q658Y4
RIFGGLEIIELACYR	LCLAT1	386	Q6UWP7
LGVCANGLLIYKDRL	EPB41L2	421	O43491
LQDYGLVVRGCLDLR	EXD2	176	Q9NVH0
TVLDCDLLLYGRGHR	HARBI1	6	Q96MB7
GSLYQGICKLLRLED	PLXNA4	131	Q9HCM2
RDRKILQLCGELYDL	PDE2A	226	O00408
LGYCSGLIDNLIRRR	NDUFC2	36	O95298
EVLRLNRCLVYLDIG	LRRC74A	296	Q0VAA2
CRRLGIIEVDYFGLQ	MYLIP	31	Q8WY64
LGRQLRYLAELCGVG	TUBGCP6	466	Q96RT7
LLLLRGGAQALECYS	LYPD3	21	O95274
IIRVYDGREILTCGR	RBBP5	221	Q15291
CVLDGLRVYLLPDGR	SBF1	896	O95248
GDRYILRQEGTRCEL	OBSCN	3491	Q5VST9
CLQTRLELYKQGLRG	CSF2	71	P04141
VYVGICRQLGDLERA	ICE1	1996	Q9Y2F5
VLQVAGLYRGLCAVR	ATPAF1	16	Q5TC12
YGVRACLGRRIAELE	CYP27A1	471	Q02318
IYGCLSGAERELILQ	KLHDC7A	471	Q5VTJ3
AEQGRLCGYRLRKDL	EMC1	676	Q8N766
GLYEKLEDIQGRLCL	DNAH9	1571	Q9NYC9
RDSLRLEAGLCLYGN	AMT	261	P48728
YLRGDRGQILVICLI	BTC	111	P35070
VLRLGNIARLELNYC	SAMM50	431	Q9Y512
LLSIYDERGARQLGL	COL5A3	106	P25940
QLLYRLGRLLLEEGS	IHH	386	Q14623
YRRLLEGEEQRLCEG	KRT83	411	P78385
RREQLKLLGDYLGLC	PLEKHM1	921	Q9Y4G2
RRRGDLLGENIYLLL	PIGB	51	Q92521
LLRLRDRHGKEYCLG	PARS2	141	Q7L3T8
NDRLLYCVPRLRLLG	FGD1	616	P98174
RLGRLGLQGYVLELC	MYBPH	96	Q13203
ARNELLILCGYIGAL	WDR17	1156	Q8IZU2
LILCGYIGALLAIRR	WDR17	1161	Q8IZU2
GNLGLVALIYVERRL	OR5K4	41	A6NMS3
RYDLLCLEGLVRGLQ	FARSB	71	Q9NSD9
ENILLCVGDAYIRRL	SRPK3	216	Q9UPE1
QLRFCLTGLLVILYG	ABCC8	166	Q09428
RRKGNYLLCSLLLGN	CNNM4	236	Q6P4Q7
ELLYNCGIQLLHIGR	CNOT10	356	Q9H9A5
LQEYLGLLYAIRCVR	SNX20	161	Q7Z614
GRDRLIRVLGYCCQL	PEX11G	16	Q96HA9
ELIGTRRIYCGLGLL	SLC16A13	331	Q7RTY0
QDLRRDYGALGISLL	SLC26A1	631	Q9H2B4
IYSNLLCGVLRGALE	TRAPPC3	126	O43617
LGYCSGLIDNLIRRR	NDUFC2-KCTD14	36	E9PQ53
CDRLLRQGYEEGLVD	UBAP1L	311	F5GYI3
ILRRYGKCGHEDLQL	ZNF430	131	Q9H8G1
GYSDGLRRILCQVGL	UBR2	326	Q8IWV8
EEIRGGGLLKYCNLL	TENT5A	286	Q96IP4
YRLLLLKGLGRRQAC	PIGM	111	Q9H3S5
LDLGYRLLAVCAANR	ZMIZ1	71	Q9ULJ6
CLYEALKRAGDRLLG	UBASH3A	126	P57075
YRRLLEGEEQRLCEG	KRT81	406	Q14533
YLIRALQLLRGSGGC	ART5	136	Q96L15
VLGCLNEQRLLGLYC	NACC2	16	Q96BF6