Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainGOLGA6L

GOLGA6L4 GOLGA6L10 GOLGA6L19 GOLGA6L9

3.12e-0861284IPR026737
DomainGOLGA2L5

GOLGA6L4 GOLGA6L10 GOLGA6L19 GOLGA6L9

5.98e-06181284PF15070
DomainGolgin_A

GOLGA6L4 GOLGA6L10 GOLGA6L19 GOLGA6L9

5.98e-06181284IPR024858
DomainZnf_PHD-finger

ASH1L DPF2 BAZ2A NFX1 UHRF2 PYGO1

1.70e-05791286IPR019787
DomainPHD

ASH1L DPF2 BAZ2A UHRF2 RAI1 PYGO1

3.36e-05891286SM00249
DomainZnf_PHD

ASH1L DPF2 BAZ2A UHRF2 RAI1 PYGO1

3.81e-05911286IPR001965
DomainZF_PHD_2

ASH1L DPF2 BAZ2A UHRF2 RAI1 PYGO1

4.86e-05951286PS50016
DomainZF_PHD_1

ASH1L DPF2 BAZ2A UHRF2 RAI1 PYGO1

5.16e-05961286PS01359
DomainGlyco_trans_43

B3GAT1 B3GAT2

1.39e-0431282IPR005027
DomainGlyco_transf_43

B3GAT1 B3GAT2

1.39e-0431282PF03360
DomainPHD

ASH1L DPF2 BAZ2A UHRF2 PYGO1

1.64e-04751285PF00628
DomainNUT

NUTM2A NUTM2B

4.60e-0451282IPR024310
DomainNUT_N

NUTM2A NUTM2B

4.60e-0451282IPR024309
DomainNUT

NUTM2A NUTM2B

4.60e-0451282PF12881
DomainZnf_FYVE_PHD

SYTL2 ASH1L DPF2 BAZ2A UHRF2 PYGO1

5.29e-041471286IPR011011
DomainAT_hook

ASH1L AHDC1 BAZ2A

8.15e-04271283SM00384
DomainAT_hook_DNA-bd_motif

ASH1L AHDC1 BAZ2A

8.15e-04271283IPR017956
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

NOLC1 ZC3H13 U2SURP DLGAP5 NUTM2A TFIP11 PTBP1 KRR1 CDCA8 HP1BP3 NCBP3 SCML2 NUTM2B ZSCAN21 BAZ2A FEN1 DDX21 MGA NOP2 SLX4 ELL RAI1 DNMT1

1.38e-129541312336373674
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

AKAP6 NOLC1 ZC3H13 TUT7 DLGAP5 ASH1L APC TFIP11 INO80 KRR1 EHD3 SCML2 ZSCAN21 OSBPL3 NFX1 ANKRD17 AFF1 CPLANE1 KIF13A DDX21 MGA UTRN SLX4 LRRC18

2.56e-1210841312411544199
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

NOLC1 FAM193B HAUS6 TCOF1 U2SURP DLGAP5 TFIP11 HP1BP3 TWF1 GPALPP1 SCML2 BAZ2A KIAA1217 CIAPIN1 FEN1 ANKRD17 DDX21 NOP2 UTRN DNMT1

3.71e-109341312033916271
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

TCOF1 ZC3H13 U2SURP POLRMT TFIP11 INO80 KRR1 AHDC1 HP1BP3 OSBPL3 A2ML1 FEN1 ANKRD17 SLC25A11 HADHB SPATS2 DDX21 NOP2 ELL

4.95e-108471311935850772
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

NOLC1 TCOF1 ZC3H13 U2SURP DLGAP5 TFIP11 INO80 PTBP1 AHDC1 HP1BP3 CLASRP SCML2 ZSCAN21 USP42 BAZ2A OSBPL3 ISG20L2 HADHB DDX21 MGA NOP2 RAI1 DNMT1

5.83e-1012941312330804502
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

DLGAP5 INO80 CDCA8 HP1BP3 NCBP3 SCML2 TRMT6 ZSCAN21 BAZ2A RAD54B FEN1 UHRF2 MGA NOP2 RAI1 DNMT1

1.36e-096081311636089195
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

NOLC1 U2SURP TUT7 DLGAP5 POLRMT TFIP11 DPF2 PTBP1 KRR1 PIK3C2A BAZ2A A2ML1 FEN1 ANKRD17 AKAP13 SLC25A11 HADHB LTF DDX21 MGA NOP2 UTRN DNMT1

1.37e-0913531312329467282
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NOLC1 TCOF1 ZC3H13 U2SURP TUT7 POLRMT KRR1 HP1BP3 BAZ2A ANKRD17 LTF DDX21 NOP2 UTRN RAI1 DNMT1

3.74e-096531311622586326
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TCOF1 KALRN DLGAP5 ADGRB3 APC TWF1 EHD3 PTPRN2 OSBPL3 N4BP2 KIAA1217 ANKRD17 SPATS2 BRSK1 MGA NOP2 NOS1 RAI1 DNMT1

4.05e-099631311928671696
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NOLC1 PHACTR2 BAD APC RGS12 TWF1 NHSL1 NKD2 PIK3C2A SH3PXD2A OSBPL3 N4BP2 KIAA1217 ANKRD17 AKAP13 KIF13A UTRN DNMT1

4.42e-098611311836931259
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

TCOF1 TUT7 NUTM2A TFIP11 PTBP1 KRR1 HP1BP3 NCBP3 TRMT6 PIK3C2A OSBPL3 FEN1 NFX1 ANKRD17 ISG20L2 SLC25A11 HADHB SPATS2 ATP1B1 DDX21 NOP2 DNMT1

9.28e-0913711312236244648
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

HAUS6 APC INO80 SCML2 NECAP2 PIK3C2A SH3PXD2A CIAPIN1 NFX1 ANKRD17 AKAP13 SLC25A11 SPATS2 DDX21 MGA NOP2

1.59e-087241311636232890
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NOLC1 TCOF1 ZC3H13 DLGAP5 TATDN2 TFIP11 DPF2 CLASRP SCML2 USP42 BAZ2A ANKRD17 AFF1 DDX21 NOP2 DNMT1

3.99e-087741311615302935
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

NOLC1 ZC3H13 TUT7 POLRMT PTBP1 KRR1 HP1BP3 TWF1 TRMT6 KIAA1217 FEN1 ANKRD17 SLC25A11 HADHB LTF SPATS2 UHRF2 DDX21 NOP2 DNMT1

5.44e-0812571312036526897
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

NOLC1 TCOF1 ZC3H13 U2SURP TFIP11 PTBP1 KRR1 HP1BP3 NCBP3 LTF SPATS2 DDX21 NOP2 RAI1

7.58e-086051311428977666
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

TCOF1 U2SURP TATDN2 DPF2 KRR1 HP1BP3 CLASRP ZSCAN21 FEN1 RNF216 SLC25A11 ATP1B1 NOP2 TP73

2.61e-076701311422990118
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

KALRN ADGRB3 APC INO80 GPALPP1 A2ML1 NFX1 SLC25A11 SPATS2 DDX21 NOP2 DNMT1

2.68e-074751311231040226
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

ASH1L APC DPF2 KRR1 TWF1 NHSL1 TRMT6 NKD2 USP42 OSBPL3 FEN1 AKAP13 HADHB MGA

3.66e-076891311436543142
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

NOLC1 TCOF1 KALRN ZC3H13 U2SURP APC TFIP11 DPF2 INO80 PTBP1 AHDC1 HP1BP3 USP42 FEN1 SLC25A11 HADHB DDX21

7.09e-0710821311738697112
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

TUT7 TFIP11 KRR1 AHDC1 KIAA1217 A2ML1 FEN1 ANKRD17 SLC25A11 SPATS2 BRSK1 CPLANE1 DDX21 NOP2

7.50e-077321311434732716
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

TUT7 DLGAP5 SYTL2 APC SHC4 TFIP11 SCML2 NECAP2 N4BP2 CIAPIN1 ROBO1 AKAP13 MGA DNMT1

7.63e-077331311434672954
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

KRR1 HP1BP3 BAZ2A FEN1 ISG20L2 DDX21 MGA NOP2 RAI1 DNMT1

8.97e-073491311025665578
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

NOLC1 TUT7 POLRMT PTBP1 KRR1 CDCA8 HP1BP3 NCBP3 ISG20L2 SLC25A11 SPATS2 DDX21 NOP2 DNMT1

1.15e-067591311435915203
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PCSK5 TUT7 POLRMT APC TFIP11 HP1BP3 OSBPL3 RAD54B ANKRD17 RNF216 AKAP13 SLC25A11 DNMT1

1.17e-066501311338777146
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

PAXX TFIP11 SCML2 BAZ2A FEN1 DDX21 MGA NOP2 DNMT1

1.37e-06283131930585729
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

NOLC1 U2SURP POLRMT KRR1 HP1BP3 ISG20L2 HADHB LTF SPATS2 DDX21 NOP2

2.35e-064831311136912080
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

NOLC1 TCOF1 ZC3H13 U2SURP TFIP11 PTBP1 KRR1 HP1BP3 GPALPP1 NECAP2 USP42 BAZ2A FEN1 SLC25A11 HADHB DDX21 NOP2 DNMT1

2.39e-0613181311830463901
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

RAB22A POLRMT APC TFIP11 INO80 KRR1 AHDC1 TWF1 SCML2 PIK3C2A BAZ2A CRACDL NFX1 ANKRD17 ISG20L2 SLC25A11 SPATS2 ATP1B1 UTRN

3.54e-0614971311931527615
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

TCOF1 U2SURP DPF2 PTBP1 AHDC1 HP1BP3 ANKRD17 HADHB SPATS2 DDX21 NOP2 TP73

3.94e-066151311231048545
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

HAUS6 TUT7 APC RGS12 NECAP2 OSBPL3 N4BP2 KIAA1217 CIAPIN1 NFX1 SLC25A11 CPLANE1 MGA ELL

4.43e-068531311428718761
Pubmed

Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.

TCOF1 HP1BP3 SCML2 BAZ2A FEN1

8.02e-0672131531248990
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NOLC1 PHACTR2 MYLK U2SURP RAB22A ASH1L PTBP1 NKIRAS2 PLA2G4D TRDN HP1BP3 GPALPP1 SH3PXD2A N4BP2 ISG20L2 HADHB DDX21 RAI1

8.23e-0614421311835575683
Pubmed

Knockdown of slit signaling during limb development leads to a reduction in humerus length.

GDF5 SLIT3 ROBO1

8.43e-0611131333347679
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

NOLC1 TCOF1 ZC3H13 U2SURP TUT7 POLRMT PTBP1 KRR1 NCBP3 NFX1 SLC25A11 DDX21 NOP2

1.21e-058071311322681889
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

TCOF1 U2SURP POLRMT APC PTBP1 HP1BP3 BAZ2A FEN1 ISG20L2 SLC25A11 HADHB DDX21 NOP2

1.24e-058091311332129710
Pubmed

Suppression of intestinal neoplasia by DNA hypomethylation.

APC DNMT1

1.41e-05213127537636
Pubmed

Complete genetic suppression of polyp formation and reduction of CpG-island hypermethylation in Apc(Min/+) Dnmt1-hypomorphic Mice.

APC DNMT1

1.41e-052131211888894
Pubmed

Adenomatous polyposis coli interacts with flap endonuclease 1 to block its nuclear entry and function.

APC FEN1

1.41e-052131222787431
Pubmed

Suppressive effect of global DNA hypomethylation on gastric carcinogenesis.

APC DNMT1

1.41e-052131220622006
Pubmed

Distributions of glucuronyltransferases, GlcAT-P and GlcAT-S, and their target substrate, the HNK-1 carbohydrate epitope in the adult mouse brain with or without a targeted deletion of the GlcAT-P gene.

B3GAT1 B3GAT2

1.41e-052131217935701
Pubmed

Reducing DNA methylation suppresses colon carcinogenesis by inducing tumor cell differentiation.

APC DNMT1

1.41e-052131225939752
Pubmed

Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice.

APC DNMT1

1.41e-052131212538347
Pubmed

Human DNA methyltransferase gene DNMT1 is regulated by the APC pathway.

APC DNMT1

1.41e-052131212538344
Pubmed

Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis.

APC DNMT1

1.41e-052131216174748
Pubmed

The Overexpression of FEN1 and RAD54B May Act as Independent Prognostic Factors of Lung Adenocarcinoma.

RAD54B FEN1

1.41e-052131226431531
Pubmed

INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis.

APC INO80

1.41e-052131229383140
Pubmed

Tissue-specific angiogenic and invasive properties of human neonatal thymus and bone MSCs: Role of SLIT3-ROBO1.

SLIT3 ROBO1

1.41e-052131232470195
Pubmed

The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model.

PCSK5 APC

1.41e-052131219737405
Pubmed

Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression.

APC FEN1

1.41e-052131212119409
Pubmed

ApcMin/+ mouse model of colon cancer: gene expression profiling in tumors.

APC DNMT1

1.41e-052131215486983
Pubmed

Stromal Cell-SLIT3/Cardiomyocyte-ROBO1 Axis Regulates Pressure Overload-Induced Cardiac Hypertrophy.

SLIT3 ROBO1

1.41e-052131238414132
Pubmed

Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing.

RAD54B FEN1

1.41e-052131219218431
Pubmed

A Sulfated Glycosaminoglycan Linkage Region is a Novel Type of Human Natural Killer-1 (HNK-1) Epitope Expressed on Aggrecan in Perineuronal Nets.

B3GAT1 B3GAT2

1.41e-052131226659409
Pubmed

Tbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectoderm.

SLIT3 ROBO1 B3GAT1

1.45e-0513131319700621
Pubmed

A human MAP kinase interactome.

BAD APC ATF6 N4BP2 ANKRD17 ROBO1 AKAP13 CPLANE1 MGA PYGO1

1.65e-054861311020936779
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

NOLC1 TCOF1 U2SURP BAD APC TFIP11 PTBP1 AHDC1 PIK3C2A ANKRD17 AFF1 SLC25A11 HADHB SPATS2 DDX21 MGA

1.96e-0512471311627684187
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

PCSK5 FAM193B KALRN PTBP1 TCEANC AHDC1 CLASRP TDRD7 NUTM2B PTPRN2 CYB5R1

2.04e-056081311116713569
Pubmed

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.

U2SURP POLRMT HP1BP3 SLC25A11 DDX21 MGA NOP2

2.18e-05221131729991511
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

NOLC1 TCOF1 ZC3H13 U2SURP TFIP11 PTBP1 KRR1 HP1BP3 ISG20L2 SLC25A11 DDX21 NOP2

2.21e-057311311229298432
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

NOLC1 HAUS6 TCOF1 KALRN ZC3H13 DLGAP5 APC AKAP13 KIF13A NOP2

2.22e-055031311016964243
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

NOLC1 PHACTR2 TCOF1 U2SURP TFIP11 TWF1 FEN1 DDX21 NOP2 UTRN

2.33e-055061311030890647
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

TCOF1 TFIP11 NCBP3 BAZ2A ISG20L2 HADHB SPATS2 MGA UTRN

2.69e-05410131926949251
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

NOLC1 PAXX ASH1L DPF2 INO80 HP1BP3 SCML2 SLC25A11 MGA DNMT1

3.62e-055331311030554943
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

AKAP6 PHACTR2 MYLK BAD PANX2 PTPRN2 BAZ2A KIF13A

3.72e-05329131817474147
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

NOLC1 HAUS6 TCOF1 APC PTBP1 HP1BP3 CTDSP2 NECAP2 ROBO1 MGA NOP2 DNMT1

3.99e-057771311235844135
Pubmed

Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons.

SLIT3 ROBO1

4.21e-053131210102269
Pubmed

MiR-211 is epigenetically regulated by DNMT1 mediated methylation and inhibits EMT of melanoma cells by targeting RAB22A.

RAB22A DNMT1

4.21e-053131227237979
Pubmed

Neuronal nitric oxide synthase-rescue of dystrophin/utrophin double knockout mice does not require nNOS localization to the cell membrane.

NOS1 UTRN

4.21e-053131222003386
Pubmed

Molecular cloning and genomic analysis of mouse glucuronyltransferase involved in biosynthesis of the HNK-1 epitope.

B3GAT1 B3GAT2

4.21e-053131211872162
Pubmed

Tannin extract from maritime pine bark exhibits anticancer properties by targeting the epigenetic UHRF1/DNMT1 tandem leading to the re-expression of TP73.

TP73 DNMT1

4.21e-053131234897340
Pubmed

Mechanism of adenomatous polyposis coli (APC)-mediated blockage of long-patch base excision repair.

APC FEN1

4.21e-053131217176113
Pubmed

Reduction of pancreatic acinar cell tumor multiplicity in Dnmt1 hypomorphic mice.

APC DNMT1

4.21e-053131221362628
Pubmed

The alpha-syntrophin PH and PDZ domains scaffold acetylcholine receptors, utrophin, and neuronal nitric oxide synthase at the neuromuscular junction.

NOS1 UTRN

4.21e-053131220720107
Pubmed

Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin.

NOS1 UTRN

4.21e-053131220483958
Pubmed

High miR-139-3p expression predicts a better prognosis for hepatocellular carcinoma: a pooled analysis.

RAD54B ISG20L2

4.21e-053131230394818
Pubmed

Human INO80 chromatin-remodelling complex contributes to DNA double-strand break repair via the expression of Rad54B and XRCC3 genes.

INO80 RAD54B

4.21e-053131220687897
Pubmed

Neuronal nitric oxide synthase localizes to utrophin expressing intercalated discs and stabilizes their structural integrity.

NOS1 UTRN

4.21e-053131226483274
Pubmed

The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.

NUTM2E NUTM2B

4.21e-053131226542179
Pubmed

The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.

NUTM2A NUTM2B

4.21e-053131222456610
Pubmed

Correlation between the expression of DNMT1, and GSTP1 and APC, and the methylation status of GSTP1 and APC in association with their clinical significance in prostate cancer.

APC DNMT1

4.21e-053131225738352
Pubmed

PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation.

TP73 DNMT1

4.21e-053131227533450
Pubmed

Gene Expression and Missplicing in the Corneal Endothelium of Patients With a TCF4 Trinucleotide Repeat Expansion Without Fuchs' Endothelial Corneal Dystrophy.

AKAP13 KIF13A

4.21e-053131231469403
Pubmed

Tumor progression in Apc(1638N) mice with Exo1 and Fen1 deficiencies.

APC FEN1

4.21e-053131217452984
Pubmed

Osteoclast-secreted SLIT3 coordinates bone resorption and formation.

SLIT3 ROBO1

4.21e-053131229504949
Pubmed

Phosphorylation of proteins by inositol pyrophosphates.

NOLC1 TCOF1

4.21e-053131215604408
Pubmed

Distinct nuclear and cytoplasmic assemblies and interactomes of the mammalian CTLH E3 ligase complex.

KRR1 HP1BP3 TRMT6 HADHB LTF NOP2

4.27e-05167131635833506
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

NOLC1 TCOF1 ZC3H13 POLRMT TFIP11 HP1BP3 NCBP3 ATF6 PIK3C2A BAZ2A N4BP2 ROBO1 AKAP13 HADHB DDX21 NOP2 DNMT1

4.54e-0514871311733957083
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

BDP1 BAD ASH1L AHDC1 HP1BP3 EHD3 ATF6 PTPRN2 SH3PXD2A KIAA1217 ANKRD17 AFF1 AKAP13 KATNIP SPATS2 UTRN RAI1

4.61e-0514891311728611215
Pubmed

Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.

NOLC1 TCOF1 U2SURP DLGAP5 PTBP1 HP1BP3 MGA NOP2 DNMT1

4.72e-05441131931239290
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

ZC3H13 U2SURP PTBP1 KRR1 TWF1 N4BP2 HADHB DDX21 MGA NOP2

4.78e-055511311034728620
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

NOLC1 TCOF1 TFIP11 HP1BP3 NCBP3 SCML2 BAZ2A NOP2

4.78e-05341131832971831
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

NOLC1 PCSK5 FAM193B PHACTR2 ZC3H13 TUT7 ASH1L AHDC1 CTDSP2 SH3PXD2A RAD54B FEN1 TOR1B SPATS2 UTRN

5.60e-0512151311515146197
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

NOLC1 TCOF1 U2SURP SHC4 PTBP1 HP1BP3 TWF1 OSBPL3 FEN1 SLC25A11 LTF DDX21 NOP2

6.42e-059491311336574265
Pubmed

The protein interaction landscape of the human CMGC kinase group.

TCOF1 APC PTBP1 KRR1 CLASRP NCBP3 AFF1 LTF SPATS2 DDX21 NOP2

6.81e-056951311123602568
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

ZC3H13 APC HP1BP3 OSBPL3 KIAA1217 AKAP13 DDX21 NOP2

7.12e-05361131830344098
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

U2SURP DPF2 AHDC1 SCML2 ZSCAN21 MGA RAI1

7.38e-05268131733640491
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NOLC1 U2SURP DPF2 PTBP1 AHDC1 GPALPP1 ZSCAN21 CIAPIN1 FEN1 HADHB UHRF2 NOP2 RAI1 DNMT1

7.50e-0511031311434189442
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

NOLC1 DPF2 KRR1 AHDC1 CLASRP NCBP3 USP42 N4BP2 DNMT1

7.56e-05469131927634302
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

TCOF1 U2SURP TFIP11 PTBP1 SCML2 FEN1 DDX21

7.92e-05271131732433965
Pubmed

Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.

KRR1 AHDC1 SCML2 NOP2 DNMT1

8.06e-05116131521282530
InteractionSMC5 interactions

NOLC1 ZC3H13 U2SURP DLGAP5 NUTM2A TFIP11 PTBP1 KRR1 CDCA8 HP1BP3 NCBP3 SCML2 NUTM2B ZSCAN21 BAZ2A FEN1 DDX21 MGA NOP2 SLX4 ELL RAI1 DNMT1

4.68e-08100012523int:SMC5
InteractionH3C3 interactions

DLGAP5 CDCA8 HP1BP3 NCBP3 SCML2 TRMT6 ZSCAN21 BAZ2A RAD54B FEN1 UHRF2 MGA NOP2 RAI1 DNMT1

4.41e-0749512515int:H3C3
InteractionNAA40 interactions

NOLC1 FAM193B HAUS6 TCOF1 U2SURP DLGAP5 TFIP11 HP1BP3 TWF1 GPALPP1 SCML2 BAZ2A KIAA1217 CIAPIN1 FEN1 ANKRD17 DDX21 NOP2 UTRN DNMT1

2.44e-0697812520int:NAA40
InteractionDOT1L interactions

TCOF1 ZC3H13 U2SURP POLRMT TFIP11 INO80 KRR1 AHDC1 HP1BP3 OSBPL3 A2ML1 FEN1 AFF1 SLC25A11 HADHB DDX21 NOP2 ELL

2.48e-0680712518int:DOT1L
InteractionMYCN interactions

NOLC1 TCOF1 ZC3H13 U2SURP TUT7 TFIP11 DPF2 PTBP1 KRR1 HP1BP3 NCBP3 NFX1 ANKRD17 AKAP13 ISG20L2 SLC25A11 HADHB SPATS2 DDX21 NOP2 ALOX12 RAI1 TP73 DNMT1

3.32e-06137312524int:MYCN
InteractionMEN1 interactions

NOLC1 TCOF1 ZC3H13 U2SURP POLRMT TFIP11 INO80 KRR1 AHDC1 HP1BP3 NCBP3 SCML2 BAZ2A OSBPL3 ANKRD17 SLC25A11 HADHB SPATS2 DDX21 NOP2

5.24e-06102912520int:MEN1
InteractionH2BC8 interactions

DLGAP5 DPF2 CDCA8 HP1BP3 NCBP3 GPALPP1 SCML2 TRMT6 ZSCAN21 BAZ2A FEN1 MGA RAI1 DNMT1

1.38e-0557612514int:H2BC8
InteractionSIRT7 interactions

NOLC1 TCOF1 ZC3H13 U2SURP TUT7 POLRMT KRR1 HP1BP3 BAZ2A ANKRD17 LTF DDX21 NOP2 UTRN RAI1 DNMT1

1.49e-0574412516int:SIRT7
InteractionCHD3 interactions

NOLC1 ZC3H13 U2SURP TFIP11 PTBP1 KRR1 HP1BP3 NCBP3 NFX1 LTF SPATS2 UHRF2 DDX21 NOP2 RAI1 TP73

1.84e-0575712516int:CHD3
InteractionRPL31 interactions

NOLC1 TCOF1 ZC3H13 U2SURP TUT7 KRR1 CDCA8 NCBP3 ZSCAN21 BAZ2A FEN1 NFX1 ISG20L2 DDX21 NOP2

2.09e-0568012515int:RPL31
InteractionUSP36 interactions

NOLC1 U2SURP POLRMT PTBP1 KRR1 HP1BP3 USP42 ISG20L2 HADHB LTF SPATS2 DDX21 NOP2 SLX4

2.13e-0559912514int:USP36
InteractionCENPA interactions

ZC3H13 CDCA8 HP1BP3 NCBP3 ZSCAN21 BAZ2A FEN1 ISG20L2 NOP2 RAI1 DNMT1

2.34e-0537712511int:CENPA
InteractionGSK3A interactions

FAM193B U2SURP APC PTBP1 AHDC1 NHSL1 ROBO1 SLC25A11 LTF BRSK1 UTRN SLX4

3.23e-0546412512int:GSK3A
InteractionHECTD1 interactions

NOLC1 U2SURP TUT7 POLRMT APC PTBP1 KRR1 CDCA8 HP1BP3 NCBP3 SH3PXD2A ISG20L2 SLC25A11 SPATS2 DDX21 NOP2 UTRN DNMT1

3.65e-0598412518int:HECTD1
InteractionSLIT3 interactions

THBS2 SLIT3 ROBO1

3.71e-05111253int:SLIT3
InteractionSRPK2 interactions

NOLC1 TCOF1 ZC3H13 U2SURP POLRMT TFIP11 PTBP1 KRR1 HP1BP3 CLASRP NCBP3 AKAP13 CPLANE1 DDX21 NOP2

3.85e-0571712515int:SRPK2
InteractionH3-3A interactions

ASH1L INO80 CDCA8 HP1BP3 NCBP3 SCML2 TRMT6 ZSCAN21 BAZ2A FEN1 HADHB UHRF2 MGA RAI1 DNMT1

6.31e-0574912515int:H3-3A
InteractionDAXX interactions

NOLC1 TFIP11 KRR1 HP1BP3 HADHB GOLGA6L9 SLX4 RAI1 TP73 DNMT1

7.14e-0535312510int:DAXX
InteractionCAMKV interactions

NOLC1 TCOF1 GPALPP1 AFF1 HADHB ELL

9.44e-051181256int:CAMKV
InteractionZNF330 interactions

NOLC1 CDCA8 HP1BP3 NCBP3 TRMT6 ZSCAN21 FEN1 DDX21 NOP2 RAI1 DNMT1

1.06e-0444612511int:ZNF330
InteractionNUP43 interactions

ZC3H13 ASH1L APC INO80 CDCA8 AHDC1 HP1BP3 NCBP3 TDRD7 GPALPP1 BAZ2A MGA SLX4

1.38e-0462512513int:NUP43
InteractionEGLN3 interactions

FAM193B HAUS6 DLGAP5 APC TATDN2 NKIRAS2 NHSL1 PIK3C2A OSBPL3 N4BP2 CIAPIN1 RAD54B ANKRD17 ROBO1 AKAP13 SLC25A11 HADHB MGA UTRN SLX4

1.38e-04129612520int:EGLN3
InteractionCBX8 interactions

TFIP11 DPF2 KRR1 SCML2 BAZ2A GOLGA6L9 MGA NOP2

1.65e-042491258int:CBX8
InteractionDHX40 interactions

ZC3H13 TFIP11 NCBP3 ZSCAN21 MGA NOP2 SLX4 RAI1

1.65e-042491258int:DHX40
InteractionSUZ12 interactions

NOLC1 ZC3H13 PTBP1 KRR1 AHDC1 HP1BP3 NCBP3 USP42 N4BP2 SLC25A11 UHRF2 NOP2 DNMT1

1.85e-0464412513int:SUZ12
InteractionCBX3 interactions

TCOF1 ZC3H13 CDCA8 AHDC1 HP1BP3 SCML2 ZSCAN21 BAZ2A FEN1 UHRF2 MGA SLX4 DNMT1

1.91e-0464612513int:CBX3
InteractionPRKRA interactions

TCOF1 IL17B TUT7 POLRMT KRR1 HP1BP3 USP42 SPATS2 DDX21 NOP2

1.98e-0440012510int:PRKRA
InteractionDDX23 interactions

NOLC1 TCOF1 ZC3H13 U2SURP TFIP11 PTBP1 CLASRP GPALPP1 DDX21 NOP2 TP73

2.02e-0448012511int:DDX23
InteractionFGFBP1 interactions

ASH1L POLRMT INO80 KRR1 HP1BP3 ANKRD17 SPATS2 DDX21

2.04e-042571258int:FGFBP1
InteractionRPL11 interactions

NOLC1 BDP1 TCOF1 KRR1 HP1BP3 USP42 OSBPL3 NFX1 ANKRD17 DDX21 NOP2 SLX4 TP73

2.09e-0465212513int:RPL11
InteractionHDAC4 interactions

KALRN ADGRB3 APC TFIP11 INO80 GPALPP1 SH3PXD2A NFX1 SLC25A11 SPATS2 GOLGA6L9 DDX21 NOP2 DNMT1

2.15e-0474412514int:HDAC4
InteractionCHD4 interactions

NOLC1 TCOF1 U2SURP TFIP11 DPF2 PTBP1 KRR1 HP1BP3 NCBP3 BAZ2A LTF DDX21 NOP2 SLX4 RAI1 DNMT1

2.28e-0493812516int:CHD4
InteractionBMI1 interactions

ZC3H13 TFIP11 DPF2 PTBP1 KRR1 HP1BP3 NCBP3 SCML2 NFX1 SLC25A11 UHRF2 MGA NOP2

2.32e-0465912513int:BMI1
InteractionADARB1 interactions

TCOF1 U2SURP TUT7 TFIP11 PTBP1 TCEANC HP1BP3 SCML2 FEN1 DDX21 NOP2

2.37e-0448912511int:ADARB1
InteractionYWHAG interactions

NOLC1 PHACTR2 ZC3H13 BAD APC KRR1 RGS12 TWF1 NHSL1 NKD2 PIK3C2A SH3PXD2A OSBPL3 N4BP2 ANKRD17 AKAP13 KIF13A UTRN DNMT1

2.46e-04124812519int:YWHAG
InteractionS100A2 interactions

FAM193B HAUS6 PAXX POLRMT CDCA8 TDRD7 NHSL1 SPATS2 BRSK1 RAI1

2.51e-0441212510int:S100A2
InteractionKIF20A interactions

NOLC1 POLRMT TFIP11 DPF2 PTBP1 KRR1 TCEANC CDCA8 RGS12 TWF1 PIK3C2A AFF1 HADHB KIF13A DDX21 NOP2 UTRN

2.71e-04105212517int:KIF20A
InteractionPRNP interactions

MYLK ASH1L APC DPF2 KRR1 TWF1 NHSL1 TRMT6 NECAP2 NKD2 USP42 OSBPL3 FEN1 AKAP13 HADHB ATP1B1 MGA NOS1

2.83e-04115812518int:PRNP
GeneFamilyPHD finger proteins

ASH1L DPF2 BAZ2A NFX1 UHRF2 PYGO1

1.54e-069072688
GeneFamilyBeta-1,3-glucuronyltransferases

B3GAT1 B3GAT2

4.68e-053722423
GeneFamilyTudor domain containing

TDRD7 UHRF2 TDRD12

4.27e-0437723780
GeneFamilyAF4/FMR2 family|Super elongation complex

AFF1 ELL

5.53e-0497221280
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

AKAP6 GARNL3 MYLK KALRN SYTL2 SLIT3 KIF13A

1.36e-06188130734e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KALRN ADGRB3 THBS2 NKD2 SH3PXD2A DDX21 ELL

1.51e-06191130708720998aa55131d7377c4c67c4c935865bd7d79
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

PIK3C2A BAZ2A N4BP2 AFF1 CPLANE1 MGA UTRN

1.62e-061931307abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYLK ADGRB3 THBS2 NKD2 SLIT3 CHRDL1 ROBO1

1.80e-0619613077d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYLK ADGRB3 THBS2 NKD2 SLIT3 CHRDL1 ROBO1

1.92e-0619813073ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

PCSK5 NDNF MYLK SYTL2 CHRDL1 ROBO1 ALOX12

2.06e-062001307a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK5 FAM193B ADAM32 GOLGA6L4 KIAA1755 TOR1B

4.34e-061451306e808502fa52baf1c400f3c9b918a167127e78af9
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

GARNL3 KALRN ZIM2 A2ML1 SLIT3 BRSK1

7.91e-06161130664891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GDF5 DLGAP5 EHD3 OSBPL3 RAD54B FEN1

8.79e-0616413065621c2e3fae84d5a2e4f1595e454bcb3a2b3f93c
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHC4 NKD2 BAZ2A CRACDL ATP1B1 UTRN

1.31e-05176130629cda51a99100ddd2928cadc92da40f001d7e1f4
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHC4 NKD2 BAZ2A CRACDL ATP1B1 UTRN

1.31e-05176130601774a86d7d92f31a056b753f9844f923038003e
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 GDF5 NKD2 PTPRN2 TP73 TDRD12

1.36e-0517713069b02fd91c110b405eba6cb74ceb90b1286535973
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

AKAP6 GARNL3 MYLK KALRN THBS2 SLIT3

1.49e-051801306d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

AKAP6 MYLK KALRN SYTL2 SLIT3 KIF13A

1.64e-051831306818fd886e0188091310825f9145fa53328f2c979
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

AKAP6 MYLK KALRN SYTL2 SLIT3 KIF13A

1.97e-0518913066b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHACTR2 KIAA1217 ROBO1 NOS1 UTRN PYGO1

2.15e-051921306dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCell368C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CDCA8 ATF6 SLIT3 CHRDL1 CFAP119 CPLANE1

2.21e-0519313065f5904cec8b2967154ef2eab3c48f51df53aca4a
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

MYLK ADGRB3 THBS2 NKD2 SLIT3 ROBO1

2.21e-051931306ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 PHACTR2 KIAA1217 ROBO1 NOS1 PYGO1

2.28e-05194130683863da11dfbe59b2d0a2c08db40b537c150588c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 PHACTR2 KIAA1217 ROBO1 NOS1 PYGO1

2.28e-0519413061bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYLK ADGRB3 NKD2 SLIT3 KIAA1755 ROBO1

2.28e-05194130689b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK ADGRB3 THBS2 NKD2 SLIT3 CHRDL1

2.41e-05196130642e9828222a9663525d571633e8a454c30bfa7f8
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 GARNL3 MYLK KALRN SYTL2 SLIT3

2.48e-051971306bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

MYLK KALRN ADGRB3 THBS2 SLIT3 ROBO1

2.48e-051971306f1c8936986123a3151140c374fcd62d6705c530b
ToppCellCOPD-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

MYLK THBS2 NKD2 SLIT3 CHRDL1 ROBO1

2.48e-051971306d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYLK ZIM2 THBS2 SLIT3 KIAA1755 ROBO1

2.48e-05197130644673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

MYLK ADGRB3 THBS2 NKD2 SLIT3 ROBO1

2.55e-05198130626e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

MYLK ADGRB3 THBS2 NKD2 SLIT3 ROBO1

2.55e-051981306df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYLK ADGRB3 THBS2 NKD2 SLIT3 ROBO1

2.55e-0519813068f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PCSK5 NDNF MYLK SYTL2 CHRDL1 ROBO1

2.63e-05199130638cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellTCGA-Stomach-Primary_Tumor|TCGA-Stomach / Sample_Type by Project: Shred V9

DLGAP5 CDCA8 OSBPL3 DDX21 NOP2 DNMT1

2.63e-05199130638f1f612b29feb868322999ceeda78e52447ec4f
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 GARNL3 MYLK KALRN SYTL2 SLIT3

2.63e-051991306b1753474152b82a0b811b9878c890a359e14919a
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma|TCGA-Stomach / Sample_Type by Project: Shred V9

DLGAP5 CDCA8 OSBPL3 DDX21 NOP2 DNMT1

2.63e-051991306b10698aee2e6c17bc559eb4f723024141f914b90
ToppCellBiopsy_Other_PF-Mesenchymal-Myofibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

MYLK THBS2 NKD2 SLIT3 CHRDL1 ROBO1

2.70e-052001306e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

GARNL3 ADGRB3 PTPRN2 KIAA1217 SLIT3 LTF

2.70e-052001306682960e28542a3d6c119047cd0131941932cfdea
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PHACTR2 KIAA1217 ROBO1 NOS1 B3GAT2 PYGO1

2.70e-0520013066a44439e4a7ce3627271375b04cfcfb9467218f4
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

AKAP6 PCSK5 MYLK IL17B SYTL2 CHRDL1

2.70e-052001306f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A|Neuronal / cells hierarchy compared to all cells using T-Statistic

PHACTR2 KIAA1217 ROBO1 NOS1 B3GAT2 PYGO1

2.70e-0520013068d51b4f7b7002ee51401ebe5eaca1e8f04bfadd5
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYLK ADGRB3 THBS2 NKD2 SLIT3 ROBO1

2.70e-052001306cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellNeuronal-Excitatory|Neuronal / cells hierarchy compared to all cells using T-Statistic

KALRN SYTL2 ADGRB3 CRACDL SLIT3 AKAP13

2.70e-0520013064409065bc7aa995354c71e0f9d6f3726cf393d6b
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

AKAP6 PCSK5 MYLK IL17B CHRDL1 CPLANE1

2.70e-052001306dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A--L4-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

PHACTR2 KIAA1217 ROBO1 NOS1 B3GAT2 PYGO1

2.70e-052001306cb1f4b0d66da5b0466ff17b29e7034d451d93e4f
ToppCellBiopsy_IPF-Mesenchymal-Myofibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

MYLK THBS2 NKD2 SLIT3 CHRDL1 ROBO1

2.70e-052001306c2c6f687c49ba790174b27c7b8b084af30b34c86
ToppCellE16.5-samps|World / Age Group, Lineage, Cell class and subclass

PTBP1 CDCA8 AHDC1 ROBO1 DNMT1

7.64e-051491305e94d075f68c1c70c89fab50b1b765b5dda650d09
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CDCA8 THBS2 NKD2 NOP2 DNMT1

8.66e-05153130565641cc82883716dba0fefb749a30174a63f4da5
ToppCellChildren_(3_yrs)-Immune-mast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SYTL2 TRDN EHD3 ZSCAN21 BRSK1

8.66e-051531305d3fb83ca984c7583b1e51c364be6c7c17f67b048
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

PDE6G MYLK THBS2 NKD2 SLIT3

1.04e-0415913053f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYLK KALRN SYTL2 SLIT3 UTRN

1.07e-04160130529c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 TG SLIT3 CHRDL1 ROBO1

1.10e-0416113051b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

MYLK KALRN SYTL2 SLIT3 UTRN

1.10e-04161130547b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

PDE6G MYLK THBS2 NKD2 SLIT3

1.20e-0416413052ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYLK KALRN SYTL2 SLIT3 UTRN

1.23e-041651305f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellICU-SEP-Lymphocyte-T_NK-dnT|ICU-SEP / Disease, Lineage and Cell Type

PHACTR2 KALRN PTPRN2 SH3PXD2A CRACDL

1.27e-04166130596d92316cee20b722fe782db9dafcceb8f2c220b
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

ADGRB3 AHDC1 SCML2 CFAP119 SPATS2

1.31e-041671305bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SHC4 PANX2 NKD2 N4BP2 KIAA1755

1.31e-04167130555c3c68af269fcf40f2b080ae4489523609ad388
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NHSL1 OSBPL3 CRACDL CPLANE1 TP73

1.46e-0417113051854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

MYLK KALRN SYTL2 SLIT3 UTRN

1.46e-041711305e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DLGAP5 CDCA8 SLAMF1 TG DNMT1

1.50e-041721305282017db72d0537ac82aecc69393ccde9590be60
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYLK KALRN SYTL2 SLC13A1 SLIT3

1.54e-0417313055416b092321c7d9b63f0418c60f2402a138355bf
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA8 EHD3 KIAA1217 CHRDL1 ISG20L2

1.67e-041761305e9152defb4fd41267fb33c42c01fd0c683280783
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA8 EHD3 KIAA1217 CHRDL1 ISG20L2

1.67e-041761305a4d269075aa0efc46fa251b379f334e50c69391d
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 MYLK SYTL2 NHSL1 ALOX12

1.67e-0417613057292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA8 EHD3 KIAA1217 CHRDL1 ISG20L2

1.67e-041761305cc6f65a7d2c622841c9d1ab3755586039d4ccc4d
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AKAP6 MYLK TRDN FEN1 SLX4

1.67e-0417613054ed73c73972334f6dc4229920205547823252fa0
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 MYLK SYTL2 NHSL1 ALOX12

1.67e-04176130588ca2f83d8301633232735f39b0683efe49d0b86
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHC4 SLAMF1 SYT16 CFAP119 ALOX12

1.76e-041781305f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYTL2 SH3PXD2A KIAA1217 GOLGA6L9 RAI1

1.81e-0417913056e965e424eebef50f0202cff75f458be395cfca1
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDF5 NDNF NKD2 PTPRN2 TP73

1.81e-041791305479116ac65488c60104a053530830763ec1f95b2
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDF5 NDNF NKD2 PTPRN2 TP73

1.81e-0417913051dfc0cb8b369aef35c59f3d4c52603dc9f3728c1
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHACTR2 SYTL2 CRACDL SLIT3 AKAP13

1.81e-041791305747a32460b257fffca30527b56a74720eb9c12e4
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP5 SYTL2 CDCA8 RAD54B DNMT1

1.81e-04179130554621d2b3a66e62aa76b7e444118878ed97c1e02
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDF5 NDNF NKD2 PTPRN2 TP73

1.81e-04179130569a1b3b05c921de6343ffe6ad998aa2b804312a7
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 THBS2 USP42 SLIT3 KIAA1755

1.81e-041791305ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCellRSV-Healthy-0|RSV / Virus stimulation, Condition and Cluster

NECAP2 B3GAT1 CPLANE1 UTRN TP73

1.85e-041801305974044056e2f7e909cb11c6f6ca89e58bf95f7e5
ToppCellmild_COVID-19_(asymptomatic)-cDC|World / disease group, cell group and cell class (v2)

TCOF1 PANX2 RGS12 TRMT6 ATP1B1

1.85e-04180130568d1c867734fb2977b01ac686b20bf602f9a6b72
ToppCellRSV-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

NECAP2 B3GAT1 CPLANE1 UTRN TP73

1.85e-041801305703a1d0f9536af94d56757eb01221878d7b7fe61
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 NDNF THBS2 NKD2 SLIT3

1.90e-041811305269b39ac65790061d54eab47a8eeb024403f0348
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 NDNF THBS2 NKD2 SLIT3

1.90e-041811305cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 NDNF THBS2 NKD2 SLIT3

1.90e-041811305c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK THBS2 SCML2 KIAA1755 CHRDL1

1.90e-041811305b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

KALRN SYTL2 ADGRB3 SLIT3 UTRN

1.95e-0418213052075efeae633550fb2eb026d0dfd741c8252482e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZIM2 OSBPL3 CRACDL NOS1 RAI1

1.95e-041821305a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NDNF MYLK A2ML1 CHRDL1 LRRC18

2.00e-04183130561a73de857f4ae02dcba3af348f436f602b28ff2
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

AKAP6 MYLK KALRN SYTL2 SLIT3

2.00e-041831305cae2ee08f985a6f005b4b8e959e465350315156a
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APC HP1BP3 ATP1B1 DDX21 UTRN

2.05e-0418413051154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DLGAP5 CDCA8 SLAMF1 RAD54B FEN1

2.05e-041841305a0831e850bc0b585296ed350fdd075c1f730308e
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP5 CDCA8 SCML2 RAD54B DNMT1

2.05e-04184130516aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCell21-Trachea-Mesenchymal-Airway_Smooth_Muscle|Trachea / Age, Tissue, Lineage and Cell class

NDNF MYLK ADGRB3 THBS2 CHRDL1

2.05e-04184130586a96cd88e50eacad1f0badfbbf6dc626f41725e
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 PCSK5 MYLK IL17B CHRDL1

2.16e-0418613056add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

PCSK5 SH3PXD2A ROBO1 SPATS2 UTRN

2.16e-041861305de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DLGAP5 CDCA8 SLAMF1 FEN1 TP73

2.16e-041861305993c58ef4445bf81bbc9b489635883848b5b4c8e
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KALRN SLAMF1 PTPRN2 LTF NOS1

2.16e-04186130592092f11ecce22c14f244e42c499af0822977e6f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 KALRN IL17B SYTL2 SLIT3

2.16e-0418613054780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

PCSK5 SH3PXD2A ROBO1 SPATS2 UTRN

2.16e-0418613050b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 IL17B SYTL2 THBS2 SLIT3

2.16e-041861305a95744b8649096bd7cfc3591a02841fa411085b3
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

PHACTR2 MYLK ZC3H13 APC PIK3C2A

2.16e-04186130503db813598b67b1e08f759758a1c2023396921fa
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AKAP6 NDNF IL17B TRDN SCML2

2.21e-041871305218c9b4f28499389c43005d9626af2ac01066027
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

AKAP6 MYLK KALRN THBS2 SLIT3

2.21e-041871305464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYLK KALRN ADGRB3 SLIT3 ROBO1

2.21e-041871305a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

MYLK ADGRB3 NKD2 SLIT3 ROBO1

2.21e-04187130592d468dde81125d51daf7abd4703741abe1ab91c
Diseaseadenoma (is_implicated_in)

APC TP73

1.59e-0521182DOID:657 (is_implicated_in)
DiseaseHematochezia

APC LTF

9.46e-0541182C0018932
Diseasetrochanter size

GDF5 CTDSP2

1.57e-0451182EFO_0010074
DiseaseEndometrial Stromal Sarcoma

NUTM2A NUTM2B

1.57e-0451182C0206630
DiseaseClear cell sarcoma of kidney

NUTM2E NUTM2B

2.35e-0461182C0334488
DiseaseTreacher Collins syndrome (implicated_via_orthology)

NOLC1 TCOF1

2.35e-0461182DOID:2908 (implicated_via_orthology)
DiseaseGastrointestinal Hemorrhage

APC LTF

5.60e-0491182C0017181
DiseaseGlaucoma

MYLK TDRD7

5.60e-0491182C0017601
DiseaseChildhood Medulloblastoma

APC SCML2 DNMT1

6.85e-04431183C0278510
DiseaseMelanotic medulloblastoma

APC SCML2 DNMT1

6.85e-04431183C1275668
DiseaseMedullomyoblastoma

APC SCML2 DNMT1

6.85e-04431183C0205833
DiseaseDesmoplastic Medulloblastoma

APC SCML2 DNMT1

6.85e-04431183C0751291
DiseaseAdult Medulloblastoma

APC SCML2 DNMT1

6.85e-04431183C0278876
DiseaseAnxiety States, Neurotic

TG RAI1 DNMT1

7.33e-04441183C0376280
DiseaseAnxiety neurosis (finding)

TG RAI1 DNMT1

7.33e-04441183C1279420
DiseaseAnxiety Disorders

TG RAI1 DNMT1

7.33e-04441183C0003469
Diseasehematocrit

KALRN ASH1L PTBP1 CTDSP2 ANKRD17 CHRDL1 AFF1 UHRF2 NYAP1 ELL RAI1 TDRD12

7.48e-04101111812EFO_0004348
Diseaseprostatic hypertrophy (is_marker_for)

BAD TP73

8.52e-04111182DOID:11132 (is_marker_for)
Diseasecolon cancer (implicated_via_orthology)

BAD APC

8.52e-04111182DOID:219 (implicated_via_orthology)
Diseaseurate measurement, bone density

AKAP6 ADGRB3 TG PTPRN2 A2ML1 KIAA1755 ROBO1 UTRN B3GAT2

8.75e-046191189EFO_0003923, EFO_0004531
DiseaseNeurobehavioral Manifestations

NOS1 RAI1

1.02e-03121182C0525041
DiseaseMedulloblastoma

APC SCML2 DNMT1

1.07e-03501183C0025149
DiseaseCongenital Hypothyroidism

CDCA8 TG

1.20e-03131182C0010308
Diseaseimpotence (implicated_via_orthology)

BAD NOS1

1.61e-03151182DOID:1875 (implicated_via_orthology)
Diseaselevel of Sterol ester (27:1/18:1) in blood serum

CLASRP ANKRD17

1.83e-03161182OBA_2045195
Diseaselung non-small cell carcinoma (is_implicated_in)

BAD LTF TP73 DNMT1

2.39e-031391184DOID:3908 (is_implicated_in)
Diseasemonocyte count

KALRN U2SURP ASH1L AHDC1 EHD3 ATF6 RNF216 AKAP13 NYAP1 DISP1 ELL RAI1 DNMT1

2.42e-03132011813EFO_0005091
Diseaserenal cell carcinoma (is_implicated_in)

APC LTF TP73

2.70e-03691183DOID:4450 (is_implicated_in)
Diseaseunipolar depression, bipolar disorder, schizophrenia

PCSK5 NCBP3

2.87e-03201182EFO_0003761, MONDO_0004985, MONDO_0005090
DiseaseSchizophrenia

APC RGS12 SH3PXD2A SLIT3 B3GAT1 NOS1 ALOX12 B3GAT2 RAI1 DNMT1

2.92e-0388311810C0036341
DiseaseJoubert syndrome 1

KATNIP CPLANE1

3.17e-03211182C4551568
Diseaseplatelet component distribution width

KALRN U2SURP PTBP1 CTDSP2 EHD3 BAZ2A AKAP13 SLC25A11 NYAP1

3.37e-037551189EFO_0007984
DiseaseProstatic Neoplasms

BAD ASH1L APC BAZ2A ROBO1 AKAP13 MGA DNMT1

3.39e-036161188C0033578
DiseaseMalignant neoplasm of prostate

BAD ASH1L APC BAZ2A ROBO1 AKAP13 MGA DNMT1

3.39e-036161188C0376358
DiseaseParkinson's disease (is_implicated_in)

GDF5 PHACTR2 NOS1

3.54e-03761183DOID:14330 (is_implicated_in)
DiseaseAlzheimer's disease (is_marker_for)

PHACTR2 BAD APC HADHB NOS1

3.80e-032571185DOID:10652 (is_marker_for)
Diseaseprostate carcinoma (is_marker_for)

BAD TP73

3.80e-03231182DOID:10286 (is_marker_for)
DiseaseMalignant tumor of colon

APC RAD54B LTF DNMT1

3.87e-031591184C0007102
DiseaseMalignant neoplasm of breast

AKAP6 KALRN PANX2 SLAMF1 CLASRP N4BP2 AFF1 ROBO1 HADHB TP73 DNMT1

3.90e-03107411811C0006142
DiseaseUnipolar Depression

KALRN EHD3 TG SLIT3 NOS1

3.92e-032591185C0041696

Protein segments in the cluster

PeptideGeneStartEntry
KPVLVNEGKKGFTDP

B3GAT1

316

Q9P2W7
FQRPKPNLSRAGKKS

BDP1

616

A6H8Y1
GRLQKPKPNAGKAAE

BDP1

706

A6H8Y1
PGLRKKLKRSNPFNE

BDP1

2536

A6H8Y1
GLVTKDPGKKPVFNA

ASH1L

281

Q9NR48
NRVLGFKPKPPKNES

ATP1B1

181

P05026
VGKLCPKNFEGPSKT

ERVK11-1

91

P61568
LGKKVQFRKPAPGAT

ELL

156

P55199
IKEIFCPKKSNGRPN

DNMT1

996

P26358
KKGLPRPKSAGTATQ

BAD

126

Q92934
RRVFPTNFPGLQKKG

ADGRB3

131

O60242
EFTQKPGFPKRGQKR

BAZ2A

1731

Q9UIF9
GFVPQKGRSDTLIKP

A2ML1

886

A8K2U0
KKKNKTSRSQPGDGP

AKAP13

2786

Q12802
GKKPNFEVGSSRQLK

CIAPIN1

161

Q6FI81
QKKSPKPVCGNGRLE

ADAM32

386

Q8TC27
GPRNKTENGLTPKKK

ATF6

156

P18850
RGGAAAKAKFIPKPQ

AHDC1

1286

Q5TGY3
PNGKLTVASPKRGQK

ANKRD17

1701

O75179
EDNGNPLNPKSKGKL

DISP1

796

Q96F81
PFKVPGKDTVTKDNG

HADHB

266

P55084
PGKAASVKQRGSKPA

HP1BP3

466

Q5SSJ5
GSKPAPKVSAAQRGK

HP1BP3

476

Q5SSJ5
APSQLQGNSFKKPKF

RAD54B

6

Q9Y620
QGNSFKKPKFIPPGR

RAD54B

11

Q9Y620
QPGGTALAPKKRSRK

RAI1

1436

Q7Z5J4
GGKGFKLRRQPSEPK

RAB22A

176

Q9UL26
PKQPVGGGQKLLTRK

NOLC1

406

Q14978
GGNFKPDTLKPKEVV

INO80

1251

Q9ULG1
QTGVGSKSKLKFLPP

PTPRN2

591

Q92932
PGESLINPGFKSKKP

PAXX

181

Q9BUH6
PATPDFRSVLGGKKK

MYLK

976

Q15746
GQTGGLTQPKKDEPK

GDF5

81

P43026
FLGLGQPRSPKSKRK

IL17B

16

Q9UHF5
GRPPKNTGKSLISTK

MGA

626

Q8IWI9
TNRPGKNLKAFVPAK

MGA

1511

Q8IWI9
PKPNRAKSLGKAGTT

KIAA1755

506

Q5JYT7
QPSPTGKDRKQGGRK

KATNIP

756

O60303
PPSKKRTQSIQGKGK

CDCA8

146

Q53HL2
VFLKSVSPANGKGKP

NHSL1

871

Q5SYE7
PSQLRNFKTPGKLKE

PCSK5

576

Q92824
PDSNKQRKGPEALGK

PIK3C2A

776

O00443
NTGKNEATGPRKPKD

KALRN

2416

O60229
EATGPRKPKDILGNK

KALRN

2421

O60229
ERRGFLSKKNQPPSK

ISG20L2

36

Q9H9L3
KNRIGNKLPPEKFAD

NCBP3

451

Q53F19
ADPRGAKPKKATQFV

NFX1

161

Q12986
PQSKSAFPLSRKNKG

NKIRAS2

171

Q9NYR9
KLNIKRNPFPKPGES

LRRC18

171

Q8N456
NSGKERSFQAKPSPK

NDNF

261

Q8TB73
KGAGKSEFRNQKPKP

KRR1

11

Q13601
PAGANRKKKINGSSP

GOLGA6L3

41

A6NEY3
PAGANRKKKINGSSP

GOLGA6L4

41

A6NEF3
PAGANRKKKINGSSP

GOLGA6L9

41

A6NEM1
PAGANRKKKVNGSSP

GOLGA6L10

41

A6NI86
PAGANRKKKVNGSSP

GOLGA6L19

41

H0YKK7
AGSQTPPFKRKGKLS

PHACTR2

21

O75167
SGPKPKAVLNQFRTD

ALOX12

616

P18054
PEKQFLKSPKGSGKP

NKD2

326

Q969F2
DKPGARTLKSEPGKQ

CRACDL

846

Q6NV74
GIDGKPRTSPKSVKF

SLC25A11

11

Q02978
NGSPSKCPRFLKVKN

NOS1

296

P29475
KNGAASKRAFKQSPP

TP73

321

O15350
ERPFQLPPGKGKSKT

CFAP119

316

A1A4V9
DGKPPQLKSGELAKR

FEN1

86

P39748
SQGLPKPEFRFKGQS

CPLANE1

2651

Q9H799
VCPGKKAKELPGQSF

CHRDL1

321

Q9BU40
EPVSSGGKPQKGKRQ

FAM193B

706

Q96PV7
QGLVSKSSPKKPRGR

CTDSP2

21

O14595
SNPKAVFKRRGSQPG

B3GAT2

256

Q9NPZ5
QPLRAKGKRPKDTFN

LINC00032

6

P0C843
PPGFIKSTQKSDKGR

GPALPP1

116

Q8IXQ4
GRPAKNVETKPDKGI

DLGAP5

246

Q15398
RGPPKDKKLLATNGT

BRSK1

761

Q8TDC3
FGGSLPAKKSDPFQK

HAUS6

521

Q7Z4H7
GETREKSPKLKNGFP

DDX21

141

Q9NR30
KEKTKPVPGYNNDTG

SLC13A1

196

Q9BZW2
ISRKPNTRKQKNGFP

POLRMT

1106

O00411
GPPKFKQRQTRQFKS

PDE6G

26

P18545
RQFKSKPPKKGVQGF

PDE6G

36

P18545
KSKPRKRLEESQGGP

GARNL3

931

Q5VVW2
IGKDAKGTLQVPKPF

OSBPL3

281

Q9H4L5
GRAPKIEKQIQSKGP

PANX2

171

Q96RD6
PGKLLRKTFSQSPQG

PLA2G4D

116

Q86XP0
KKAGSQKPTPEGRES

NYAP1

141

Q6ZVC0
PSNTKQGERKPPKVF

KIF13A

41

Q9H1H9
RGLNLAPSPANKAKK

NUTM2A

806

Q8IVF1
APSPANKAKKRPLFG

NUTM2A

811

Q8IVF1
RGLNLAPSPANKAKK

NUTM2B

806

A6NNL0
APSPANKAKKRPLFG

NUTM2B

811

A6NNL0
RGLNLAPSPANKAKK

NUTM2E

806

B1AL46
DKKKRKANTQGPSFP

PYGO1

36

Q9Y3Y4
EKRKNPFNSSKLPEG

SYTL2

156

Q9HCH5
INARFSKSGKPPIND

UTRN

41

P46939
SGGPSSPKRLKAQKE

TATDN2

46

Q93075
KSPKFQLFGSPSGQK

LTF

301

P02788
GKQTGLEQKPKFSRS

SYT16

216

Q17RD7
KPKKGAGNPQASTLA

TCOF1

1276

Q13428
DLKKALQRNKFPGPS

TDRD12

426

Q587J7
KPGPLQKKLDSFPAQ

SLAMF1

286

Q13291
NRPGTLDKPGKQSKL

KIAA1217

1756

Q5T5P2
KENGKKPGSFPTQLR

SPATA31D4

426

Q6ZUB0
KRKNGENTFKRIGPP

RNF216

756

Q9NWF9
KKPNPAPLRDKGNSV

TDRD7

136

Q8NHU6
TGKGHFNIQPNKKSP

CYB5R1

156

Q9UHQ9
KKGPQSLFNAPRGKK

NOP2

91

P46087
VDPKKPFRKLNAFGN

EHD3

116

Q9NZN3
GLETPKGANRKKNLP

SLX4

1541

Q8IY92
DELESGKRPKKPGQS

U2SURP

856

O15042
GKRPKKPGQSFQEQV

U2SURP

861

O15042
GIPERQKGKPNVTSK

AKAP6

1901

Q13023
PPGKGSRQRKAEDKQ

AFF1

776

P51825
SNKGPRILKPGEKST

APC

2161

P25054
AGKETGAAKPKLTPQ

CLASRP

561

Q8N2M8
GANGAIKKRKPPVKF

SHC4

231

Q6S5L8
KGTPKSLGKLQKQPA

SLIT3

1256

O75094
KGQSKKQPSGTTKRP

UHRF2

651

Q96PU4
KENGKKPGSFPTQLR

SPATA31D3

426

P0C874
FKKGLPQRKPRTSQT

SPATS2

526

Q86XZ4
KSKPSPQKDQALGDG

USP42

71

Q9H9J4
PKAKTRTLFGKDVPG

ZNF542P

56

Q5EBM4
NEKGTKPPLQEAGSK

ZSCAN21

246

Q9Y5A6
KPPLQEAGSKKGRES

ZSCAN21

251

Q9Y5A6
PSRGKASADKQKGVP

RGS12

1106

O14924
KLFPVRGNKEENSGP

TCEANC

91

Q8N8B7
VKNITPRKKGPNSGK

SCML2

301

Q9UQR0
DKFPIEGGQKDPKQR

SH3PXD2A

56

Q5TCZ1
GEFQFPPKSLNKREG

TPRG1L

146

Q5T0D9
EQKSKKGPDGLALPN

DPF2

256

Q92785
KGRGNKAAKRDLPPA

ROBO1

1561

Q9Y6N7
GGSLQPKKKREEPTA

TRMT6

71

Q9UJA5
KQSKDPLGKDPQEGT

ZIM2

296

Q9NZV7
NGSVPKSPGKVLKRT

TRDN

21

Q13061
NRKTIGAKQFRGPDP

THBS2

36

P35442
KRPKEAGPQGKATQA

PRR30

316

Q53SZ7
LQKKKITPGNYGNTP

TUT7

51

Q5VYS8
GNSPLHRFKKPGSKN

PTBP1

431

P26599
QAIPGTRSAIGKPKK

TG

711

P01266
PRKLKTGGNFKPSQK

TFIP11

116

Q9UBB9
AAQQSKKKRGPRTPP

ZC3H13

1021

Q5T200
QSFAKPKGPAGKRGI

TWF1

321

Q12792
TGFRNNKNPKKPLTL

TOR1B

91

O14657
KNLGGNPFRKTANPK

N4BP2

6

Q86UW6
KKKEGAAGNPRVRPA

NECAP2

166

Q9NVZ3