Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP hydrolysis activity

MYH7 ERCC6 RNF213 CHD8 ATP10A DNAH7 ABCB4 RUVBL1 CHD5 ATP2C2 CCT6B ATP11A RAD54L

3.92e-0744110213GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

MYH7 ERCC6 ACSS1 RNF213 CHD8 ATP10A DNAH7 ABCB4 RUVBL1 CHD5 ATP2C2 CCT6B MYH15 ATP11A RAD54L

5.16e-0761410215GO:0140657
GeneOntologyMolecularFunctioncalmodulin binding

MYH7 CAMKK1 IQGAP2 UBR4 RYR1 CAMKK2 TJP1 MYH15

2.37e-052301028GO:0005516
GeneOntologyMolecularFunctioncalcium-dependent phospholipase C activity

PLCG1 PLCH1

2.58e-0521022GO:0050429
GeneOntologyMolecularFunctionbone sialoprotein binding

ANXA2 ANXA2P2

2.58e-0521022GO:0044730
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

ERCC6 CHD8 CHD5 RAD54L

3.72e-05371024GO:0140658
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

MYH7 ERCC6 RNF213 CHD8 ATP10A DNAH7 ABCB4 RUVBL1 CHD5 ATP2C2 CCT6B RAB7A ATP11A RAD54L

3.93e-0577510214GO:0017111
GeneOntologyMolecularFunctionfloppase activity

ATP10A ABCB4 ATP11A

6.90e-05161023GO:0140328
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

ERBB2 HK1 CAMKK1 SAMD8 PAK4 PFKM CDK14 STK31 PRKD3 PIKFYVE BMPR1A BMX CAMKK2 POLK REV1

8.14e-0593810215GO:0016772
GeneOntologyMolecularFunctionpyrophosphatase activity

MYH7 ERCC6 RNF213 CHD8 ATP10A DNAH7 ABCB4 RUVBL1 CHD5 ATP2C2 CCT6B RAB7A ATP11A RAD54L

9.19e-0583910214GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

MYH7 ERCC6 RNF213 CHD8 ATP10A DNAH7 ABCB4 RUVBL1 CHD5 ATP2C2 CCT6B RAB7A ATP11A RAD54L

9.31e-0584010214GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

MYH7 ERCC6 RNF213 CHD8 ATP10A DNAH7 ABCB4 RUVBL1 CHD5 ATP2C2 CCT6B RAB7A ATP11A RAD54L

9.31e-0584010214GO:0016818
GeneOntologyMolecularFunctioncadherin binding involved in cell-cell adhesion

ANXA2 PAK4 EPCAM

1.18e-04191023GO:0098641
GeneOntologyMolecularFunctionprotein kinase activity

ERBB2 HK1 CAMKK1 PAK4 CDK14 STK31 PRKD3 PIKFYVE BMPR1A BMX CAMKK2

2.47e-0460010211GO:0004672
GeneOntologyMolecularFunctionphospholipase A2 inhibitor activity

ANXA2 ANXA2P2

2.56e-0451022GO:0019834
GeneOntologyMolecularFunctionRNA polymerase II C-terminal domain phosphoserine binding

SCAF4 RTF1

2.56e-0451022GO:1990269
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

ERBB2 HK1 CAMKK1 PAK4 PFKM CDK14 STK31 PRKD3 PIKFYVE BMPR1A BMX CAMKK2

2.66e-0470910212GO:0016773
GeneOntologyMolecularFunctionphosphatidylinositol phospholipase C activity

PLCG1 PLCG2 PLCH1

3.09e-04261023GO:0004435
GeneOntologyMolecularFunctionphosphoprotein binding

SCAF4 RTF1 MID1 PLCG1 PLCG2

3.36e-041171025GO:0051219
GeneOntologyMolecularFunctionRNA polymerase binding

ERBB2 ERCC6 SCAF4 RTF1

3.42e-04651024GO:0070063
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ATP10A ABCB4 ATP11A

3.86e-04281023GO:0140326
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERCC6 CHD8 RUVBL1 CHD5 POLK RAD54L REV1

3.95e-042621027GO:0140097
GeneOntologyMolecularFunctionkinase binding

MAPKAP1 ERBB2 SPDYE17 SPDYE10 TPRKB PFKM SPDYE12 SPDYE11 SPDYE15 SPDYE3 SPDYE8 PLCG1 PLCG2 SPDYE14

4.06e-0496910214GO:0019900
GeneOntologyMolecularFunctionphospholipase C activity

PLCG1 PLCG2 PLCH1

4.29e-04291023GO:0004629
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

ERCC6 CHD8 RUVBL1 CHD5 RAD54L

4.89e-041271025GO:0008094
GeneOntologyMolecularFunctionprotein kinase binding

MAPKAP1 ERBB2 SPDYE17 SPDYE10 TPRKB SPDYE12 SPDYE11 SPDYE15 SPDYE3 SPDYE8 PLCG1 PLCG2 SPDYE14

4.99e-0487310213GO:0019901
GeneOntologyMolecularFunctionkinase activity

ERBB2 HK1 CAMKK1 PAK4 PFKM CDK14 STK31 PRKD3 PIKFYVE BMPR1A BMX CAMKK2

5.20e-0476410212GO:0016301
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ATP10A ABCB4

7.09e-0481022GO:0090554
GeneOntologyMolecularFunctionhelicase activity

ERCC6 CHD8 RUVBL1 CHD5 RAD54L

1.31e-031581025GO:0004386
GeneOntologyMolecularFunctionRNA polymerase II C-terminal domain binding

SCAF4 RTF1

1.38e-03111022GO:0099122
GeneOntologyMolecularFunctionRNA polymerase core enzyme binding

ERBB2 SCAF4 RTF1

1.57e-03451023GO:0043175
GeneOntologyMolecularFunctionphosphoserine residue binding

SCAF4 RTF1

1.65e-03121022GO:0050815
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERCC6 PIWIL4 CHD8 SLFN14 RUVBL1 CHD5 POLK TRMT5 RAD54L REV1

1.70e-0364510210GO:0140640
GeneOntologyMolecularFunctionphospholipase inhibitor activity

ANXA2 ANXA2P2

1.94e-03131022GO:0004859
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

CAMKK1 PAK4 CDK14 STK31 PRKD3 PIKFYVE BMPR1A CAMKK2

2.05e-034461028GO:0004674
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ATP10A ABCB4 ATP11A

2.26e-03511023GO:0140303
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ATP10A ATP11A

2.26e-03141022GO:0140333
GeneOntologyMolecularFunctionS100 protein binding

ANXA2 ANXA2P2

2.60e-03151022GO:0044548
GeneOntologyMolecularFunctionprotein serine kinase activity

CAMKK1 PAK4 CDK14 STK31 PRKD3 PIKFYVE CAMKK2

2.61e-033631027GO:0106310
GeneOntologyMolecularFunctionWnt receptor activity

FZD1 FZD4

3.34e-03171022GO:0042813
GeneOntologyMolecularFunctionflippase activity

ATP10A ATP11A

3.34e-03171022GO:0140327
GeneOntologyMolecularFunctionlipase inhibitor activity

ANXA2 ANXA2P2

3.75e-03181022GO:0055102
GeneOntologyMolecularFunctioncell-cell adhesion mediator activity

ANXA2 PAK4 EPCAM

3.76e-03611023GO:0098632
GeneOntologyMolecularFunctionDNA helicase activity

ERCC6 CHD8 RUVBL1

3.93e-03621023GO:0003678
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

ATP10A ABCB4

4.62e-03201022GO:0008525
GeneOntologyMolecularFunctionsphingolipid transporter activity

ATP10A ABCB4

4.62e-03201022GO:0046624
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

SCAF4 RTF1 RUVBL1

4.69e-03661023GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

SCAF4 RTF1 RUVBL1

4.69e-03661023GO:0001098
GeneOntologyMolecularFunctioncalcium ion binding

ANXA2 ANXA2P2 PCDH11Y DNAH7 RYR1 FAT1 CAMKK2 PLCG1 PLCH1 NOTCH2

4.96e-0374910210GO:0005509
GeneOntologyMolecularFunctionAMP binding

ACSS1 PFKM

5.09e-03211022GO:0016208
GeneOntologyMolecularFunctioncarbohydrate kinase activity

HK1 PFKM

5.09e-03211022GO:0019200
GeneOntologyMolecularFunctionprotein phosphorylated amino acid binding

SCAF4 RTF1 PLCG2

5.31e-03691023GO:0045309
GeneOntologyMolecularFunctionlipase activity

LIPK PLCG1 PLCG2 PLCH1

5.50e-031381024GO:0016298
GeneOntologyMolecularFunctionphospholipid transporter activity

ATP10A ABCB4 ATP11A

6.45e-03741023GO:0005548
GeneOntologyBiologicalProcesspositive regulation of low-density lipoprotein particle receptor binding

ANXA2 ANXA2P2

2.19e-052972GO:1905597
GeneOntologyBiologicalProcesspositive regulation of receptor-mediated endocytosis involved in cholesterol transport

ANXA2 ANXA2P2

6.55e-053972GO:1905602
GeneOntologyBiologicalProcessnegative regulation of low-density lipoprotein particle receptor catabolic process

ANXA2 ANXA2P2

6.55e-053972GO:0032804
GeneOntologyBiologicalProcessregulation of plasma membrane organization

ANXA2 ANXA2P2 ATP10A

1.08e-0420973GO:1903729
GeneOntologyBiologicalProcesspositive regulation of low-density lipoprotein particle clearance

ANXA2 ANXA2P2

1.31e-044972GO:1905581
GeneOntologyBiologicalProcessnegative regulation of receptor catabolic process

ANXA2 ANXA2P2

1.31e-044972GO:2000645
GeneOntologyBiologicalProcesspositive regulation of intracellular cholesterol transport

ANXA2 ANXA2P2

1.31e-044972GO:0032385
GeneOntologyBiologicalProcesspositive regulation of intracellular sterol transport

ANXA2 ANXA2P2

1.31e-044972GO:0032382
GeneOntologyBiologicalProcesspositive regulation of protein phosphorylation

MAPKAP1 ERBB2 ERCC6 ANXA2 ANXA2P2 FZD1 FZD4 CAMKK2 SPDYE3 PLCG2 EIF4G3 NOTCH2

1.48e-047249712GO:0001934
GeneOntologyBiologicalProcesscell-cell junction maintenance

MTSS1 F2RL1 TJP1

1.67e-0423973GO:0045217
GeneOntologyBiologicalProcessphosphatidylinositol-mediated signaling

PLCG1 PLCG2 PLCH1

1.90e-0424973GO:0048015
GeneOntologyBiologicalProcesspositive regulation of plasma membrane repair

ANXA2 ANXA2P2

2.17e-045972GO:1905686
GeneOntologyBiologicalProcessregulation of low-density lipoprotein particle receptor binding

ANXA2 ANXA2P2

2.17e-045972GO:1905595
GeneOntologyBiologicalProcesspositive regulation of intracellular lipid transport

ANXA2 ANXA2P2

2.17e-045972GO:0032379
GeneOntologyBiologicalProcesstranslesion synthesis

ZBTB1 POLK REV1

2.42e-0426973GO:0019985
GeneOntologyBiologicalProcesspositive regulation of phosphorylation

MAPKAP1 ERBB2 ERCC6 ANXA2 ANXA2P2 FZD1 FZD4 CAMKK2 SPDYE3 PLCG2 EIF4G3 NOTCH2

2.94e-047809712GO:0042327
GeneOntologyBiologicalProcesspositive regulation of low-density lipoprotein receptor activity

ANXA2 ANXA2P2

3.24e-046972GO:1905599
GeneOntologyBiologicalProcesslipid localization

ANXA2 ANXA2P2 RNF213 ATP10A STX12 ABCB4 FZD4 OSBPL6 ATP11A IL1A

3.26e-045659710GO:0010876
GeneOntologyBiologicalProcessmembrane organization

BTBD8 ANXA2 ANXA2P2 MTSS1 F2RL1 ATP10A STX12 ABCB4 PIKFYVE GCLC RAB7A ATP11A PLCG2

3.46e-049149713GO:0061024
GeneOntologyBiologicalProcessnegative regulation of programmed cell death

MAPKAP1 ERBB2 HK1 PAK4 DNAJB6 CHD8 MADD FZD1 GCLC TJP1 ARNT2 PLCG2 IL1A EPCAM NOTCH2

3.62e-0411719715GO:0043069
GeneOntologyBiologicalProcessphospholipase C-activating G protein-coupled receptor signaling pathway

GPR17 F2RL1 CCKBR PRKD3 NMBR

4.14e-04133975GO:0007200
GeneOntologyBiologicalProcesscholesterol transport

ANXA2 ANXA2P2 STX12 ABCB4 OSBPL6

4.29e-04134975GO:0030301
GeneOntologyBiologicalProcessregulation of low-density lipoprotein particle receptor catabolic process

ANXA2 ANXA2P2

4.53e-047972GO:0032803
GeneOntologyBiologicalProcesslow-density lipoprotein particle receptor catabolic process

ANXA2 ANXA2P2

4.53e-047972GO:0032802
GeneOntologyBiologicalProcesslow-density lipoprotein receptor particle metabolic process

ANXA2 ANXA2P2

4.53e-047972GO:0032799
GeneOntologyBiologicalProcessangiogenesis

ERBB2 ANXA2 ANXA2P2 PAK4 RNF213 FZD4 BMPR1A TJP1 PLCG1 IL1A NOTCH2

4.91e-047089711GO:0001525
GeneOntologyBiologicalProcessin utero embryonic development

MTSS1 DNAJB6 CHD8 RTF1 BMPR1A TJP1 ARNT2 ATP11A PLCG1 NOTCH2

4.96e-045969710GO:0001701
GeneOntologyBiologicalProcesssterol transport

ANXA2 ANXA2P2 STX12 ABCB4 OSBPL6

5.07e-04139975GO:0015918
GeneOntologyBiologicalProcessregulation of receptor-mediated endocytosis involved in cholesterol transport

ANXA2 ANXA2P2

6.02e-048972GO:1905600
GeneOntologyBiologicalProcessregulation of plasma membrane repair

ANXA2 ANXA2P2

6.02e-048972GO:1905684
GeneOntologyBiologicalProcesspositive regulation of receptor binding

ANXA2 ANXA2P2

6.02e-048972GO:1900122
GeneOntologyBiologicalProcesslipid transport

ANXA2 ANXA2P2 ATP10A STX12 ABCB4 FZD4 OSBPL6 ATP11A IL1A

6.33e-04506979GO:0006869
GeneOntologyBiologicalProcessregulation of cholesterol transport

ANXA2 ANXA2P2 ABCB4 OSBPL6

6.36e-0483974GO:0032374
GeneOntologyBiologicalProcessregulation of sterol transport

ANXA2 ANXA2P2 ABCB4 OSBPL6

6.36e-0483974GO:0032371
GeneOntologyCellularComponentruffle

ERBB2 ANXA2 ANXA2P2 MTSS1 BMX PLCG1 PLCG2

5.28e-05206987GO:0001726
GeneOntologyCellularComponentAnxA2-p11 complex

ANXA2 ANXA2P2

6.51e-053982GO:1990665
GeneOntologyCellularComponentPCSK9-AnxA2 complex

ANXA2 ANXA2P2

6.51e-053982GO:1990667
GeneOntologyCellularComponentmembrane raft

HK1 ANXA2 ANXA2P2 STX12 ABCB4 PIKFYVE BMPR1A PLCG2

3.04e-04362988GO:0045121
GeneOntologyCellularComponentmembrane microdomain

HK1 ANXA2 ANXA2P2 STX12 ABCB4 PIKFYVE BMPR1A PLCG2

3.15e-04364988GO:0098857
GeneOntologyCellularComponentmyelin sheath adaxonal region

ANXA2 ANXA2P2

4.50e-047982GO:0035749
GeneOntologyCellularComponentcell-cell junction

ANXA2 PAK4 MTSS1 ABCB4 FZD4 PIKFYVE FAT1 TJP1 PLCG1 EPCAM

4.55e-045919810GO:0005911
GeneOntologyCellularComponentMLL1/2 complex

KMT2B CHD8 RUVBL1

4.92e-0433983GO:0044665
GeneOntologyCellularComponentcell leading edge

ERBB2 IQGAP2 ANXA2 ANXA2P2 MTSS1 FAT1 BMX PLCG1 PLCG2

5.70e-04500989GO:0031252
GeneOntologyCellularComponentintercellular canaliculus

ABCB4 TJP1

7.67e-049982GO:0046581
GeneOntologyCellularComponentbasolateral plasma membrane

ERBB2 SLC2A9 ANXA2 ANXA2P2 TJP1 ATP2C2 EPCAM

7.76e-04320987GO:0016323
GeneOntologyCellularComponentpinosome

ANXA2 ANXA2P2

1.16e-0311982GO:0044352
GeneOntologyCellularComponentmacropinosome

ANXA2 ANXA2P2

1.16e-0311982GO:0044354
GeneOntologyCellularComponentbasal plasma membrane

ERBB2 SLC2A9 ANXA2 ANXA2P2 TJP1 ATP2C2 EPCAM

1.39e-03354987GO:0009925
GeneOntologyCellularComponentruffle membrane

ERBB2 BMX PLCG1 PLCG2

1.68e-03108984GO:0032587
GeneOntologyCellularComponentphospholipid-translocating ATPase complex

ATP10A ATP11A

1.91e-0314982GO:1990531
GeneOntologyCellularComponentearly endosome

ERBB2 ANXA2 ANXA2P2 F2RL1 STX12 PIKFYVE OSBPL6 ATP11A

1.91e-03481988GO:0005769
GeneOntologyCellularComponentbasal part of cell

ERBB2 SLC2A9 ANXA2 ANXA2P2 TJP1 ATP2C2 EPCAM

2.02e-03378987GO:0045178
GeneOntologyCellularComponentlipid droplet

ANXA2 ANXA2P2 RNF213 RAB7A

2.18e-03116984GO:0005811
GeneOntologyCellularComponentmyosin complex

MYH7 MYH15 MYH16

2.69e-0359983GO:0016459
GeneOntologyCellularComponentSchmidt-Lanterman incisure

ANXA2 ANXA2P2

2.83e-0317982GO:0043220
MousePhenoabnormal vascular development

ERBB2 ANXA2 ANXA2P2 UBR4 RNF213 PFKM SLFN14 FZD4 TJP1 ATP11A PLCG1 IL1A

3.29e-055427612MP:0000259
MousePhenoabnormal atrium myocardium morphology

ERBB2 PIKFYVE ATP11A

6.70e-0515763MP:0010493
MousePhenoabnormal placenta labyrinth morphology

UBR4 PAK4 DNAJB6 TJP1 ATP11A EPCAM NOTCH2

8.66e-05194767MP:0001716
MousePhenoabnormal cardiovascular development

ERBB2 KMT2B ANXA2 ANXA2P2 UBR4 RNF213 PFKM SLFN14 RYR1 FZD4 TJP1 ATP11A PLCG1 IL1A

9.23e-058027614MP:0002925
DomainNPIP

NPIPA1 NPIPA7 NPIPB2 NPIPA5

6.58e-0714974IPR009443
DomainSNF2_N

ERCC6 CHD8 CHD5 RAD54L

2.20e-0532974IPR000330
DomainSNF2_N

ERCC6 CHD8 CHD5 RAD54L

2.20e-0532974PF00176
DomainPLC-gamma

PLCG1 PLCG2

2.67e-052972IPR016279
DomainEF-hand_like

PLCG1 PLCG2 PLCH1

5.91e-0515973PF09279
DomainPI-PLC-Y

PLCG1 PLCG2 PLCH1

5.91e-0515973PF00387
DomainPLCYc

PLCG1 PLCG2 PLCH1

5.91e-0515973SM00149
DomainPLipase_C_Pinositol-sp_Y

PLCG1 PLCG2 PLCH1

5.91e-0515973IPR001711
DomainPIPLC_Y_DOMAIN

PLCG1 PLCG2 PLCH1

5.91e-0515973PS50008
DomainPI-PLC_fam

PLCG1 PLCG2 PLCH1

5.91e-0515973IPR001192
DomainPLC_EF-hand-like

PLCG1 PLCG2 PLCH1

5.91e-0515973IPR015359
DomainPI-PLC-X

PLCG1 PLCG2 PLCH1

1.05e-0418973PF00388
DomainPLCXc

PLCG1 PLCG2 PLCH1

1.05e-0418973SM00148
DomainP-loop_NTPase

MYH7 THNSL1 ERCC6 RNF213 CHD8 SLFN14 DNAH7 ABCB4 RUVBL1 TJP1 CHD5 RAB7A MYH15 RAD54L

1.19e-048489714IPR027417
DomainPIPLC_X_DOMAIN

PLCG1 PLCG2 PLCH1

1.24e-0419973PS50007
DomainPLipase_C_PInositol-sp_X_dom

PLCG1 PLCG2 PLCH1

1.24e-0419973IPR000909
DomainIMS

POLK REV1

1.59e-044972PF00817
DomainIMS_C

POLK REV1

1.59e-044972PF11799
DomainUMUC

POLK REV1

1.59e-044972PS50173
Domain-

POLK REV1

1.59e-0449723.30.1490.100
DomainDNA_pol_Y-fam_little_finger

POLK REV1

1.59e-044972IPR017961
Domain-

PLCG1 PLCG2 PLCH1

2.87e-04259733.20.20.190
DomainPLC-like_Pdiesterase_TIM-brl

PLCG1 PLCG2 PLCH1

2.87e-0425973IPR017946
DomainUmuC

POLK REV1

3.95e-046972IPR001126
Domain-

THNSL1 ERCC6 RNF213 CHD8 SLFN14 DNAH7 ABCB4 RUVBL1 TJP1 CHD5 RAB7A RAD54L

4.79e-0474697123.40.50.300
DomainPROTEIN_KINASE_ATP

ERBB2 CAMKK1 PAK4 CDK14 STK31 PRKD3 BMPR1A BMX CAMKK2

6.39e-04459979PS00107
DomainATPase_P-typ_cyto_domN

ATP10A ATP2C2 ATP11A

7.88e-0435973IPR023299
DomainProtein_kinase_ATP_BS

ERBB2 CAMKK1 PAK4 CDK14 PRKD3 BMPR1A BMX CAMKK2

8.02e-04379978IPR017441
DomainATPase_P-typ_P_site

ATP10A ATP2C2 ATP11A

8.56e-0436973IPR018303
DomainP_typ_ATPase

ATP10A ATP2C2 ATP11A

8.56e-0436973IPR001757
DomainATPASE_E1_E2

ATP10A ATP2C2 ATP11A

8.56e-0436973PS00154
DomainATPase_P-typ_transduc_dom_A

ATP10A ATP2C2 ATP11A

9.28e-0437973IPR008250
DomainE1-E2_ATPase

ATP10A ATP2C2 ATP11A

9.28e-0437973PF00122
DomainProt_kinase_dom

ERBB2 CAMKK1 PAK4 CDK14 STK31 PRKD3 BMPR1A BMX CAMKK2

9.99e-04489979IPR000719
DomainPROTEIN_KINASE_DOM

ERBB2 CAMKK1 PAK4 CDK14 STK31 PRKD3 BMPR1A BMX CAMKK2

1.06e-03493979PS50011
DomainCENP-B_N

TIGD2 JRKL

1.17e-0310972PF04218
DomainFrizzled

FZD1 FZD4

1.42e-0311972IPR000539
DomainFrizzled

FZD1 FZD4

1.42e-0311972PF01534
Domain-

PIKFYVE CCT6B

1.42e-03119723.30.260.10
DomainTCP-1-like_intermed

PIKFYVE CCT6B

1.42e-0311972IPR027410
DomainFrizzled

FZD1 FZD4

1.42e-0311972SM01330
DomainHTH_Psq

TIGD2 JRKL

1.70e-0312972IPR007889
DomainHTH_PSQ

TIGD2 JRKL

1.70e-0312972PS50960
DomainCENPB

TIGD2 JRKL

1.70e-0312972SM00674
DomainDDE_1

TIGD2 JRKL

1.70e-0312972PF03184
DomainDDE_SF_endonuclease_dom

TIGD2 JRKL

1.70e-0312972IPR004875
DomainHTH_CENPB

TIGD2 JRKL

2.01e-0313972PS51253
DomainHTH_Tnp_Tc5

TIGD2 JRKL

2.01e-0313972PF03221
DomainHTH_CenpB_DNA-bd_dom

TIGD2 JRKL

2.01e-0313972IPR006600
DomainKinase-like_dom

ERBB2 CAMKK1 PAK4 CDK14 STK31 PRKD3 BMPR1A BMX CAMKK2

2.03e-03542979IPR011009
DomainP_typ_ATPase_c

ATP10A ATP11A

2.33e-0314972IPR032630
DomainP-type_ATPase_N

ATP10A ATP11A

2.33e-0314972IPR032631
DomainP-type_ATPase_IV

ATP10A ATP11A

2.33e-0314972IPR006539
DomainPhoLip_ATPase_C

ATP10A ATP11A

2.33e-0314972PF16212
DomainPhoLip_ATPase_N

ATP10A ATP11A

2.33e-0314972PF16209
DomainHelicase_C

ERCC6 CHD8 CHD5 RAD54L

2.34e-03107974PF00271
DomainHELICc

ERCC6 CHD8 CHD5 RAD54L

2.34e-03107974SM00490
DomainHelicase_C

ERCC6 CHD8 CHD5 RAD54L

2.43e-03108974IPR001650
DomainHELICASE_CTER

ERCC6 CHD8 CHD5 RAD54L

2.51e-03109974PS51194
DomainHELICASE_ATP_BIND_1

ERCC6 CHD8 CHD5 RAD54L

2.51e-03109974PS51192
DomainDEXDc

ERCC6 CHD8 CHD5 RAD54L

2.51e-03109974SM00487
DomainSer/Thr_kinase_AS

CAMKK1 PAK4 CDK14 STK31 PRKD3 BMPR1A CAMKK2

2.59e-03357977IPR008271
DomainHelicase_ATP-bd

ERCC6 CHD8 CHD5 RAD54L

2.59e-03110974IPR014001
DomainS_TKc

CAMKK1 PAK4 CDK14 STK31 PRKD3 BMPR1A CAMKK2

2.67e-03359977SM00220
DomainGroEL-like_apical_dom

PIKFYVE CCT6B

2.68e-0315972IPR027409
DomainCpn60/TCP-1

PIKFYVE CCT6B

2.68e-0315972IPR002423
DomainCpn60_TCP1

PIKFYVE CCT6B

2.68e-0315972PF00118
Domain-

PIKFYVE CCT6B

2.68e-03159723.50.7.10
DomainMyosin_N

MYH7 MYH15

2.68e-0315972PF02736
DomainMyosin_N

MYH7 MYH15

2.68e-0315972IPR004009
DomainPROTEIN_KINASE_ST

CAMKK1 PAK4 CDK14 STK31 PRKD3 BMPR1A CAMKK2

2.80e-03362977PS00108
DomainFrizzled/SFRP

FZD1 FZD4

3.06e-0316972IPR015526
DomainPH

PRKD3 BMX OSBPL6 PLCG1 PLCG2 PLCH1

3.29e-03278976SM00233
DomainPH_DOMAIN

PRKD3 BMX OSBPL6 PLCG1 PLCG2 PLCH1

3.35e-03279976PS50003
DomainPH_domain

PRKD3 BMX OSBPL6 PLCG1 PLCG2 PLCH1

3.40e-03280976IPR001849
DomainPkinase

CAMKK1 PAK4 CDK14 STK31 PRKD3 BMPR1A CAMKK2

3.71e-03381977PF00069
DomainMyosin_tail_1

MYH7 MYH15

3.87e-0318972PF01576
DomainMyosin_tail

MYH7 MYH15

3.87e-0318972IPR002928
DomainMyosin-like_IQ_dom

MYH7 MYH15

4.31e-0319972IPR027401
Domain-

MYH7 MYH15

4.31e-03199724.10.270.10
DomainFRI

FZD1 FZD4

4.77e-0320972SM00063
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MAPKAP1 ERBB2 CAMKK1 PAK4 DNAJB6 CDK14 DNAH7 MADD BMX TJP1 OSBPL6 PLCH1 EIF4G3 NOTCH2 CCSER1

8.34e-088611091536931259
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYH7 HK1 IQGAP2 ANXA2 MTRES1 UBR4 DNAJB6 PFKM STK31 F2RL1 ABCB4 BMPR1A GCLC TJP1 CHD5 MYH15 ATP11A PLCH1 EIF4G3

1.11e-0714421091935575683
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

MAPKAP1 HK1 HECTD3 UBR4 PAK4 DNAJB6 MRPL45 PFKM USP16 UBE2O CAMKK2 MRPS17 TMEM209 RAB7A MRPS5 PLCH1 EIF4G3 NOTCH2

8.51e-0714871091833957083
Pubmed

The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes.

ERBB2 UBR4 DNAJB6 FAT1 NOTCH2

2.64e-0669109526792178
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

IQGAP2 MRPL45 STX12 PRKD3 PIKFYVE FAT1 UBE2O TJP1 MRPS17 TMEM209 RAB7A MRPS5 NOTCH2

9.25e-069521091338569033
Pubmed

Phospholipase C gamma 2 is essential for specific functions of Fc epsilon R and Fc gamma R.

PLCG1 PLCG2

9.73e-062109212471105
Pubmed

Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy.

ANXA2 ANXA2P2

9.73e-062109219536308
Pubmed

Differential AMP-activated Protein Kinase (AMPK) Recognition Mechanism of Ca2+/Calmodulin-dependent Protein Kinase Kinase Isoforms.

CAMKK1 CAMKK2

9.73e-062109227151216
Pubmed

HER2 Overexpression Triggers an IL1α Proinflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance.

ERBB2 IL1A

9.73e-062109229382706
Pubmed

Annexin A2 modulates radiation-sensitive transcriptional programming and cell fate.

ANXA2 ANXA2P2

9.73e-062109223148505
Pubmed

EpCAM expression varies significantly and is differentially associated with prognosis in the luminal B HER2(+), basal-like, and HER2 intrinsic subtypes of breast cancer.

ERBB2 EPCAM

9.73e-062109223519058
Pubmed

Cloning of mouse Ca2+/calmodulin-dependent protein kinase kinase beta (CaMKKbeta) and characterization of CaMKKbeta and CaMKKalpha distribution in the adult mouse brain.

CAMKK1 CAMKK2

9.73e-062109212654522
Pubmed

ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.

ANXA2 ANXA2P2

9.73e-062109238290972
Pubmed

The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats.

ANXA2 ANXA2P2

9.73e-06210923013423
Pubmed

Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis.

ANXA2 ANXA2P2

9.73e-062109235064931
Pubmed

Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.

ANXA2 ANXA2P2

9.73e-062109228130864
Pubmed

Sodium and potassium regulate endothelial phospholipase C-γ and Bmx.

BMX PLCG1

9.73e-062109224785188
Pubmed

Localization of annexin II in the paranodal regions and Schmidt-Lanterman incisures in the peripheral nervous system.

ANXA2 ANXA2P2

9.73e-062109217549680
Pubmed

Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice.

ANXA2 ANXA2P2

9.73e-062109239384746
Pubmed

Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.

ANXA2 ANXA2P2

9.73e-062109220826156
Pubmed

Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.

ANXA2 ANXA2P2

9.73e-062109227468426
Pubmed

Possible CaMKK-dependent regulation of AMPK phosphorylation and glucose uptake at the onset of mild tetanic skeletal muscle contraction.

CAMKK1 CAMKK2

9.73e-062109217213473
Pubmed

Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.

ANXA2 ANXA2P2

9.73e-062109219841537
Pubmed

Evaluation of HER2 expression in urothelial carcinoma cells as a biomarker for circulating tumor cells.

ERBB2 EPCAM

9.73e-062109232212383
Pubmed

Oncogenic forms of the neu/HER2 tyrosine kinase are permanently coupled to phospholipase C gamma.

ERBB2 PLCG1

9.73e-06210921676673
Pubmed

Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice.

ANXA2 ANXA2P2

9.73e-062109227389701
Pubmed

Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation.

ANXA2 ANXA2P2

9.73e-062109217360942
Pubmed

Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina.

ANXA2 ANXA2P2

9.73e-062109219587120
Pubmed

Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate.

ANXA2 ANXA2P2

9.73e-062109219022301
Pubmed

Myosin gene mutation correlates with anatomical changes in the human lineage.

MYH15 MYH16

9.73e-062109215042088
Pubmed

Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.

ANXA2 ANXA2P2

9.73e-062109238253182
Pubmed

Role of Ca(2+)/calmodulin-dependent protein kinase kinase in adrenal aldosterone production.

CAMKK1 CAMKK2

9.73e-062109225679868
Pubmed

Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis.

ANXA2 ANXA2P2

9.73e-062109222185818
Pubmed

The isoforms of phospholipase C-gamma are differentially used by distinct human NK activating receptors.

PLCG1 PLCG2

9.73e-062109215972651
Pubmed

A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events.

ANXA2 ANXA2P2

9.73e-062109221486955
Pubmed

Lipid raft endocytosis and exosomal transport facilitate extracellular trafficking of annexin A2.

ANXA2 ANXA2P2

9.73e-062109221737841
Pubmed

Molecular species of phospholipids in a murine stem-cell line responsive to erythropoietin.

PLCG1 PLCG2

9.73e-06210928615781
Pubmed

Regulation of the low-dose radiation paracrine-specific anchorage-independent growth response by annexin A2.

ANXA2 ANXA2P2

9.73e-062109219580511
Pubmed

Positive selection of a gene family during the emergence of humans and African apes.

NPIPA1 NPIPA8

9.73e-062109211586358
Pubmed

Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth.

ANXA2 ANXA2P2

9.73e-062109236739096
Pubmed

Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.

ANXA2 ANXA2P2

9.73e-062109222517898
Pubmed

Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.

ANXA2 ANXA2P2

9.73e-062109230462534
Pubmed

Co-localization of Interleukin-1α and Annexin A2 at the plasma membrane in response to oxidative stress.

ANXA2 IL1A

9.73e-062109232615410
Pubmed

Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis.

ANXA2 ANXA2P2

9.73e-062109238092984
Pubmed

Elevated content of the tyrosine kinase substrate phospholipase C-gamma 1 in primary human breast carcinomas.

ERBB2 PLCG1

9.73e-06210921683701
Pubmed

Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.

ANXA2 ANXA2P2

9.73e-062109221572519
Pubmed

Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice.

ANXA2 ANXA2P2

9.73e-062109221788340
Pubmed

The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis of Cryptococcus neoformans and Impacts Survival in Fungal Infection.

ANXA2 ANXA2P2

9.73e-062109227371724
Pubmed

Restoration of responsiveness of phospholipase Cγ2-deficient platelets by enforced expression of phospholipase Cγ1.

PLCG1 PLCG2

9.73e-062109225793864
Pubmed

Translesional DNA synthesis through a C8-guanyl adduct of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro: REV1 inserts dC opposite the lesion, and DNA polymerase kappa potentially catalyzes extension reaction from the 3'-dC terminus.

POLK REV1

9.73e-062109219628463
Pubmed

Ca2+/calmodulin kinase kinase alpha is dispensable for brain development but is required for distinct memories in male, though not in female, mice.

CAMKK1 CAMKK2

9.73e-062109217015468
Pubmed

Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice.

ANXA2 ANXA2P2

9.73e-062109231817350
Pubmed

ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Î’3.

ANXA2 ANXA2P2

9.73e-062109237832154
Pubmed

Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice.

ANXA2 ANXA2P2

9.73e-062109230902828
Pubmed

Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis.

ANXA2 ANXA2P2

9.73e-062109224742684
Pubmed

Calcium/calmodulin kinase kinase beta has a male-specific role in memory formation.

CAMKK1 CAMKK2

9.73e-062109217207577
Pubmed

Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.

ANXA2 ANXA2P2

9.73e-062109232687500
Pubmed

Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.

ANXA2 ANXA2P2

9.73e-062109222453828
Pubmed

Agents that bind annexin A2 suppress ocular neovascularization.

ANXA2 ANXA2P2

9.73e-062109220607799
Pubmed

Calcium/calmodulin-dependent protein kinase kinase 2 regulates macrophage-mediated inflammatory responses.

CAMKK1 CAMKK2

9.73e-062109222334678
Pubmed

The G-protein-coupled CCK2 receptor associates with phospholipase Cgamma1.

CCKBR PLCG1

9.73e-062109215196926
Pubmed

A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study.

ANXA2 ANXA2P2

9.73e-062109231253864
Pubmed

The explanation for the blockade of glycolysis in early mouse embryos.

HK1 PFKM

9.73e-06210924275392
Pubmed

Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo.

ANXA2 ANXA2P2

9.73e-062109219628708
Pubmed

Annexin A2 binds to the localization signal in the 3' untranslated region of c-myc mRNA.

ANXA2 ANXA2P2

9.73e-062109215654879
Pubmed

Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis.

ANXA2 ANXA2P2

9.73e-062109220847146
Pubmed

Spatiotemporal role of SETD2-H3K36me3 in murine pancreatic organogenesis.

ANXA2 ANXA2P2 EPCAM

1.06e-0514109338265933
Pubmed

Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy.

STX12 RAB7A PLCG1 PLCG2

1.12e-0544109438351062
Pubmed

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.

ERBB2 FAT1 PLCG1 EPCAM NOTCH2

1.21e-0594109532062451
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

ERBB2 THNSL1 HK1 MTRES1 ACSS1 UBR4 RNF213 MRPL45 PFKM NUDCD2 PIKFYVE MRPS17 TMEM209 RAB7A MRPS5 TRMT5

1.73e-0514961091632877691
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

RNF213 PSMD12 MADD PIKFYVE UBE2O TJP1 MID1 ARNT2 TMEM209 PLCH1 MED27

2.00e-057331091134672954
Pubmed

Human immunodeficiency virus-1 glycoproteins gp120 and gp160 specifically inhibit the CD3/T cell-antigen receptor phosphoinositide transduction pathway.

PLCG1 PLCG2 PLCH1

2.36e-051810931979339
Pubmed

STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.

ANXA2 ANXA2P2

2.91e-053109235098646
Pubmed

The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.

ANXA2 ANXA2P2

2.91e-053109235413401
Pubmed

Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases.

ANXA2 ANXA2P2

2.91e-053109228694388
Pubmed

High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2.

ANXA2 ANXA2P2

2.91e-053109227470587
Pubmed

Increased intracellular calcium activates serum and glucocorticoid-inducible kinase 1 (SGK1) through a calmodulin-calcium calmodulin dependent kinase kinase pathway in Chinese hamster ovary cells.

CAMKK1 CAMKK2

2.91e-053109212628440
Pubmed

Annexins--unique membrane binding proteins with diverse functions.

ANXA2 ANXA2P2

2.91e-053109215169834
Pubmed

Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9.

ANXA2 ANXA2P2

2.91e-053109224808179
Pubmed

The Annexin a2 Promotes Development in Arthritis through Neovascularization by Amplification Hedgehog Pathway.

ANXA2 ANXA2P2

2.91e-053109226963384
Pubmed

Annexin A2 links poor myofiber repair with inflammation and adipogenic replacement of the injured muscle.

ANXA2 ANXA2P2

2.91e-053109228334824
Pubmed

Annexin II interactions with the annexin II receptor enhance multiple myeloma cell adhesion and growth in the bone marrow microenvironment.

ANXA2 ANXA2P2

2.91e-053109222223826
Pubmed

Phospholipase Cγ2 plays a role in TCR signal transduction and T cell selection.

PLCG1 PLCG2

2.91e-053109222837484
Pubmed

Real time fluorescence imaging of PLC gamma translocation and its interaction with the epidermal growth factor receptor.

PLCG1 PLCG2

2.91e-053109211331309
Pubmed

Annexin-2 is a regulator of stromal cell-derived factor-1/CXCL12 function in the hematopoietic stem cell endosteal niche.

ANXA2 ANXA2P2

2.91e-053109221108988
Pubmed

Multifaceted recognition of vertebrate Rev1 by translesion polymerases ζ and κ.

POLK REV1

2.91e-053109222700975
Pubmed

Spleen tyrosine kinase influences the early stages of multilineage differentiation of bone marrow stromal cell lines by regulating phospholipase C gamma activities.

PLCG1 PLCG2

2.91e-053109228786489
Pubmed

Tau complexes with phospholipase C-gamma in situ.

PLCG1 PLCG2

2.91e-05310929592050
Pubmed

Control of cortical axon elongation by a GABA-driven Ca2+/calmodulin-dependent protein kinase cascade.

CAMKK1 CAMKK2

2.91e-053109219864584
Pubmed

FOXQ1 promotes the osteogenic differentiation of bone mesenchymal stem cells via Wnt/β-catenin signaling by binding with ANXA2.

ANXA2 ANXA2P2

2.91e-053109232943107
Pubmed

Prostaglandin-endoperoxide synthase-2 deletion affects the natural trafficking of Annexin A2 in monocytes and favours venous thrombosis in mice.

ANXA2 ANXA2P2

2.91e-053109228536720
Pubmed

Annexin II is a thiazolidinedione-responsive gene involved in insulin-induced glucose transporter isoform 4 translocation in 3T3-L1 adipocytes.

ANXA2 ANXA2P2

2.91e-053109214726447
Pubmed

Mitochondrially mediated integrin αIIbβ3 protein inactivation limits thrombus growth.

ANXA2 ANXA2P2

2.91e-053109224014035
Pubmed

Annexin A2 contributes to lung injury and fibrosis by augmenting factor Xa fibrogenic activity.

ANXA2 ANXA2P2

2.91e-053109228283478
Pubmed

SHP-2 modulates interleukin-1-induced Ca2+ flux and ERK activation via phosphorylation of phospholipase Cgamma1.

PLCG1 IL1A

2.91e-053109215563458
Pubmed

Annexin A2 promotes angiogenesis after ischemic stroke via annexin A2 receptor - AKT/ERK pathways.

ANXA2 ANXA2P2

2.91e-053109236367512
Pubmed

Revealing Annexin A2 and ARF-6 enrollment during Trypanosoma cruzi extracellular amastigote-host cell interaction.

ANXA2 ANXA2P2

2.91e-053109226416603
Pubmed

Annexin A2 depletion delays EGFR endocytic trafficking via cofilin activation and enhances EGFR signaling and metastasis formation.

ANXA2 ANXA2P2

2.91e-053109223792445
Pubmed

A biosensor capable of identifying low quantities of breast cancer cells by electrical impedance spectroscopy.

ERBB2 EPCAM

2.91e-053109231015522
Pubmed

Cell surface interaction of annexin A2 and galectin-3 modulates epidermal growth factor receptor signaling in Her-2 negative breast cancer cells.

ERBB2 ANXA2

2.91e-053109226438086
InteractionRHOB interactions

ERBB2 IQGAP2 ANXA2 PAK4 STX12 PRKD3 BMPR1A FAT1 TJP1 TMEM209 OSBPL6 RAB7A MRPS5 ATP11A PLCH1 NOTCH2

2.78e-068409816int:RHOB
InteractionCAMK1 interactions

GPR17 CAMKK1 PSMD12 CDK14 CAMKK2 EIF4G3

1.11e-05103986int:CAMK1
InteractionNPHS2 interactions

ERBB2 UBR4 DNAJB6 FAT1 NOTCH2

1.49e-0564985int:NPHS2
InteractionCTR9 interactions

MAPKAP1 ERCC6 DNAJB6 RTF1 BMX RUVBL1 POLR1E EIF4G3

1.82e-05233988int:CTR9
CytobandEnsembl 112 genes in cytogenetic band chr7q11

SPDYE17 SPDYE10 SPDYE9 SPDYE12 SPDYE11 SPDYE13 SPDYE15 SPDYE8 SPDYE14

2.28e-082711119chr7q11
Cytoband7q11.23

SPDYE10 SPDYE9 SPDYE8 SPDYE14

9.43e-059711147q11.23
CytobandEnsembl 112 genes in cytogenetic band chr17q12

ERBB2 MRPL45 SLFN14 CCT6B

4.87e-041491114chr17q12
Cytoband5q13

F2RL1 POLK

1.30e-032211125q13
Cytoband16p13.11

NPIPA1 NPIPA5

1.42e-0323111216p13.11
Cytoband4q22.1

TIGD2 CCSER1

1.81e-032611124q22.1
Cytoband17q12

ERBB2 SLFN14 CCT6B

1.82e-0399111317q12
Cytoband16q24.1

ATP2C2 PLCG2

2.91e-0333111216q24.1
GeneFamilySpeedy/RINGO cell cycle regulator family

SPDYE9 SPDYE3 SPDYE8

1.65e-0512783756
GeneFamilyMyosin heavy chains

MYH7 MYH15 MYH16

3.39e-05157831098
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCG1 PLCG2 PLCH1

7.12e-0519783832
GeneFamilyPhospholipases

PLCG1 PLCG2 PLCH1

7.86e-0442783467
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD1 FZD4

9.85e-0411782286
GeneFamilyHelix-turn-helix CENPB type domain containing

TIGD2 JRKL

1.39e-0313782533
GeneFamilyATPase phospholipid transporting

ATP10A ATP11A

1.86e-03157821210
GeneFamilyDNA polymerases

POLK REV1

4.38e-0323782535
GeneFamilyMitochondrial ribosomal proteins

MRPL45 MRPS17 MRPS5

4.83e-0379783646
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000

THNSL1 ERCC6 DNAJB6 RNF213 PIWIL4 MRPL45 STK31 ATP10A RUVBL1 GCLC TRMT5 EPCAM RAD54L REV1

2.32e-058109914gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

THNSL1 ERCC6 DNAJB6 STK31 ATP10A MADD PIKFYVE GCLC TMEM209 PLCG2 TRMT5 EPCAM RAD54L REV1

2.65e-058209914gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BTBD8 GANC MTSS1 BMX PLCG2 CCSER1

2.14e-06156107658b9520fce6e259b36c3d59e82b712f5e7729e3e
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRPF3 SLFN14 F2RL1 UBE2O IL1A EPCAM

2.56e-06161107660f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCellP28-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYH7 ACSS1 PIWIL4 GCLC ATP11A EPCAM

4.15e-0617510768a4ed775ff973123dbcfe9c809959d11a62450c9
ToppCellmild-B_memory|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MTSS1 CDK14 PRKD3 PIKFYVE FAT1 PLCG2

8.66e-061991076e6ac9a0959b0de2c6a99298feb7715aa80ade1dd
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial-Astrocyte|GW10 / Sample Type, Dataset, Time_group, and Cell type.

IQGAP2 ACSS1 ARL17A GCLC POLR1E NOTCH2

8.91e-06200107698a994692440cb4f505b050276f0c8022c814a21
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial|GW10 / Sample Type, Dataset, Time_group, and Cell type.

IQGAP2 ACSS1 ARL17A GCLC POLR1E NOTCH2

8.91e-062001076ef222dc4a205d670172dae74990bdb952ac92e5b
ToppCelldroplet-Tongue-Unstain-18m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR1 TJP1 POLK JRKL NOTCH2

1.75e-051331075f7d0763b5eec2db33044d6850fd57462494038c1
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue-3|TCGA-Thryoid / Sample_Type by Project: Shred V9

DNAH7 ATP2C2 MYH15 PLCH1 CCSER1

3.53e-0515410754e9203c220a44c70cd7979796a0b461991422257
ToppCellfacs-Marrow-KLS-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB2 BRPF3 SLFN14 ABCB4 UBE2O

4.50e-051621075860ebf2390b4ad86475ad54717cbefcf61cd3b2a
ToppCellfacs-Marrow-KLS-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB2 BRPF3 SLFN14 ABCB4 UBE2O

4.50e-05162107514e9f8aaba308619eb9da90796c336e76cedac1f
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BTBD8 MTSS1 BMX PLCG2 CCSER1

4.50e-051621075ded08da888d8c481f0f96d1e0bfd03d617966910
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THNSL1 RYR1 UBE2O PLCG2 MED27

5.81e-051711075e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KMT2B MTSS1 PRKD3 PIKFYVE PLCG2

6.31e-051741075ebe6ce173ad12d4a2afa39f8d6185c0e4f97fb1e
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)|Hippocampus / BrainAtlas - Mouse McCarroll V32

GPR17 PAK4 USP16 EPCAM

6.32e-05891074a707477b4aad91817ead162474e9a3c92326f60b
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P2-Tnr|Hippocampus / BrainAtlas - Mouse McCarroll V32

GPR17 PAK4 USP16 EPCAM

6.32e-058910741d2891e2ab271eae6ded2891208bd2bf37a17500
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P2|Hippocampus / BrainAtlas - Mouse McCarroll V32

GPR17 PAK4 USP16 EPCAM

6.32e-05891074e58b9da18cce5553e18f716c6637fedaaf4858fa
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

GPR17 PAK4 USP16 EPCAM

6.32e-058910744b807b23f0c315c8293a62278d48c67c9be25a1c
ToppCelldroplet-Spleen-nan-18m-Hematologic-erythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRPF3 SLFN14 ABCB4 UBE2O

6.60e-0590107485e5280b5b7d79fed3d356070843a26b50af944b
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERCC6 ACSS1 FZD1 UBE2O NOTCH2

7.03e-05178107509d2687e0d79f12e90af35fc1c0453d249cf2d19
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MTSS1 CDK14 ABCB4 PLCG2 CCSER1

8.22e-051841075d18e94839a62fca536ae1630c154e5d0aafc44c5
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ATP2C2 ATP11A PLCH1 EPCAM CCSER1

8.22e-051841075fa4915b0498f3069fd5ef497286445528f75187e
ToppCelldroplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAMD8 MTSS1 ATP10A CHD5 EPCAM

8.65e-051861075f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCelldroplet-Lung-nan-21m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAMD8 MTSS1 ATP10A CHD5 EPCAM

8.65e-0518610758f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ATP2C2 ATP11A PLCH1 EPCAM CCSER1

8.65e-051861075bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATP2C2 ATP11A PLCH1 EPCAM CCSER1

8.87e-051871075db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK1 ACSS1 CDK14 ARNT2 EPCAM

9.32e-051891075e127e3be626bc513e151d41812f0b7adb89d5da6
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SAMD8 MTSS1 ATP10A CHD5 EPCAM

9.32e-051891075f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK1 ACSS1 CDK14 ARNT2 EPCAM

9.32e-051891075ff637ae0afdb1fdc67451be7e1e4fe575fbcfff4
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ATP2C2 ATP11A PLCH1 EPCAM CCSER1

9.56e-051901075625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH7 PIWIL4 GCLC ATP11A EPCAM

9.80e-05191107508b1d3b3be78bf7fd9e9039027e35275f2be88d0
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH7 PIWIL4 GCLC ATP11A EPCAM

9.80e-051911075f896fb490c4a17adac5e00ed9b6e6145eab1e564
ToppCell5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GANC MTSS1 BMX PLCG2 CCSER1

9.80e-05191107554f07e4de61735051498846afb44b1798bed8144
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MTSS1 CDK14 ABCB4 PLCG2 CCSER1

1.03e-0419310756e6c5ae39ea880ba809019a7d39f50e4e02007ed
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MTSS1 CDK14 ABCB4 PLCG2 CCSER1

1.03e-041931075c04ac5884be4245b75d211046f04d76ae0cfb998
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDK14 ABCB4 PIKFYVE PLCG2 CCSER1

1.03e-041931075749faa5c592ee354733f5a7363a4277ef3462b93
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RNF213 DNAH7 ATP11A PLCH1 CCSER1

1.05e-041941075e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

THNSL1 BTBD8 UBR4 MYH15 JRKL

1.05e-0419410755031f324628ff12a33e84cc52157be4786e0961d
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SAMD8 MTSS1 PRKD3 PLCG2 CCSER1

1.05e-041941075d852aebf7a763b9a776c4570711f0c759f591910
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MTSS1 CDK14 PRKD3 PIKFYVE PLCG2

1.08e-041951075481989d2e5bd2582da3d86b0155c4d6615317067
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MTSS1 CDK14 PRKD3 PIKFYVE PLCG2

1.08e-0419510756108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B-Memory_B_cells|lymph-node_spleen / Manually curated celltypes from each tissue

CDK14 PIKFYVE PLCG2 NOTCH2 CCSER1

1.08e-0419510758b307079cee67fc1df55277d0cab21ea4b97e552
ToppCellCOVID-19_Convalescent-Lymphoid_B-B_intermediate|COVID-19_Convalescent / Disease group, lineage and cell class

CDK14 ABCB4 PIKFYVE PLCG2 CCSER1

1.08e-041951075b213f19dad4c8d5a6bf20cadb1135fb2bb0b40ee
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial-Astrocyte|GW19 / Sample Type, Dataset, Time_group, and Cell type.

IQGAP2 ACSS1 RNF213 FAT1 NOTCH2

1.16e-041981075bfad1c51cf884ff7ce89f8278820800582541dc7
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

IQGAP2 ACSS1 RNF213 FAT1 NOTCH2

1.16e-0419810756372e65242236c497d9b3be147092897c1609d22
ToppCell5'-Adult-LargeIntestine-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMX PLCG2 EPCAM NOTCH2 CCSER1

1.16e-041981075a631be84e29c277216d89ec6265bd43e87c1dc86
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

MRPL45 PSMD12 USP16 RTF1 TJP1

1.16e-04198107576d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

IQGAP2 ANXA2 PSMD12 USP16 RTF1

1.19e-04199107553ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCellCOVID-19-COVID-19_Convalescent-Lymphocyte-B-B_intermediate|COVID-19_Convalescent / Disease, condition lineage and cell class

CDK14 ABCB4 PIKFYVE PLCG2 CCSER1

1.22e-042001075fdc0df661a34e0db3279334bdeebfdf60c85ef41
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MTSS1 RNF213 FZD4 CAMKK2 TJP1

1.22e-042001075bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

IQGAP2 ACSS1 RNF213 FAT1 NOTCH2

1.22e-0420010753a954d9d542e52c9b181f0850a09b1bff0a0c82d
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC2A9 ANXA2 MID1 ATP2C2 CCSER1

1.22e-042001075d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellmild-B_intermediate|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CDK14 ABCB4 PIKFYVE PLCG2 CCSER1

1.22e-042001075fe815824e9e4be3f3db73610e3814a7fd533da65
ToppCellmild-B_intermediate|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CDK14 ABCB4 PIKFYVE PLCG2 CCSER1

1.22e-0420010758e3132a1fe3708f725c5c4077878fb87bbea3678
ToppCellmild-B_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MTSS1 CDK14 ABCB4 PLCG2 CCSER1

1.22e-042001075222789b897e2a683bbfd1d00b6fd8705015d90df
Drugmercury

MYH7 ANXA2 CDK14 ZBTB1 RYR1 SCAF4 PIKFYVE GCLC ATP2C2 PLCG1 IL1A NOTCH2

5.66e-0654210212CID000023931
Drugfura 2

F2RL1 RYR1 CCKBR PRKD3 ATP2C2

1.09e-05651025CID000057054
DrugC14:1n-5

HK1 ANXA2 PFKM

1.40e-05111023CID000068344
DrugNSC618487

CAMKK1 PAK4 F2RL1 USP16 MADD PRKD3 PIKFYVE BMX CAMKK2 TJP1 ATP2C2 PLCG1 PLCG2 PLCH1 IL1A

1.72e-0593310215CID000005279
DrugST271

PLCG1 PLCG2 PLCH1 IL1A

1.79e-05351024CID006439072
DrugAC1L1KS5

F2RL1 RYR1 PRKD3 PIKFYVE ATP2C2 PLCG1 PLCG2 NMBR PLCH1

1.96e-053341029CID000005631
Drugnorathyriol

PRKD3 PLCG1 PLCG2 PLCH1

2.24e-05371024CID005281656
DrugLobeline alpha (-) hydrochoride [134-63-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A

ERBB2 KMT2B PAK4 FZD1 FZD4 PRKD3 EIF4G3

3.01e-0519710272763_DN
DrugSulfachloropyridazine [80-32-0]; Up 200; 14uM; MCF7; HT_HG-U133A

MTSS1 DNAH7 RYR1 ABCB4 CAMKK2 MID1 IL1A

3.21e-0519910273944_UP
Diseaseresponse to phenylephrine

IQGAP2 ATP10A NPIPB2

2.41e-0517993EFO_0010152
DiseaseMyocardial Ischemia

HK1 PFKM F2RL1 GCLC RAB7A IL1A

2.93e-05176996C0151744
Diseasereticulocyte measurement

HK1 IQGAP2 PFKM SLFN14 NPIPB2 ABCB4 PIKFYVE FAT1 UBE2O SPDYE3 MYH15 ATP11A PLCG2

5.11e-0510539913EFO_0010700
DiseaseCongenital myopathy with fiber type disproportion

MYH7 RYR1

1.66e-046992cv:C0546264
Diseasereticulocyte count

HK1 IQGAP2 PFKM SLFN14 F2RL1 NPIPB2 ABCB4 PIKFYVE FAT1 UBE2O ATP11A PLCG2

1.99e-0410459912EFO_0007986
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH7 MYH15

4.93e-0410992DOID:0111269 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH7 MYH15

4.93e-0410992DOID:0111602 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH7 MYH15

4.93e-0410992DOID:0111596 (implicated_via_orthology)
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH7 MYH15

4.93e-0410992DOID:0110454 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH7 MYH15

4.93e-0410992DOID:0080719 (implicated_via_orthology)
DiseaseMuscular dystrophy, limb-girdle, autosomal dominant

MYH7 DNAJB6

4.93e-0410992cv:C5675009
Diseaseinclusion body myositis (implicated_via_orthology)

MYH7 MYH15

4.93e-0410992DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH7 MYH15

4.93e-0410992DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH7 MYH15

4.93e-0410992DOID:0080326 (implicated_via_orthology)
DiseaseGlioblastoma Multiforme

PRKD3 FAT1 POLK NOTCH2

5.42e-04111994C1621958
Diseasepeanut allergy measurement, parental genotype effect measurement

RYR1 ATP2C2

6.01e-0411992EFO_0005939, EFO_0007017
DiseaseEnzymopathy

HK1 GCLC

6.01e-0411992C0520572
Diseasecholestasis (biomarker_via_orthology)

ABCB4 TJP1 IL1A

6.03e-0449993DOID:13580 (biomarker_via_orthology)
Diseasedistal myopathy (implicated_via_orthology)

MYH7 MYH15

7.20e-0412992DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH7 MYH15

7.20e-0412992DOID:2106 (implicated_via_orthology)
Diseasepolychlorinated biphenyls measurement, gestational serum measurement

CCKBR CCSER1

7.20e-0412992EFO_0007042, EFO_0007964
DiseaseAutosomal Dominant Myotubular Myopathy

MYH7 RYR1

8.48e-0413992C3661489
DiseaseCentronuclear myopathy

MYH7 RYR1

8.48e-0413992C0175709
DiseaseX-linked centronuclear myopathy

MYH7 RYR1

8.48e-0413992C0410203
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH7 MYH15

8.48e-0413992DOID:397 (implicated_via_orthology)
DiseaseMyopathy, Centronuclear, 1

MYH7 RYR1

8.48e-0413992C4551952
DiseaseCongenital Structural Myopathy

MYH7 RYR1

8.48e-0413992C0752282
DiseaseMyopathy, Centronuclear, Autosomal Dominant

MYH7 RYR1

9.88e-0414992C1834558
DiseaseTubular Aggregate Myopathy

MYH7 RYR1

9.88e-0414992C0410207
DiseaseNeoplasm of lung

ERBB2 ERCC6

9.88e-0414992cv:C0024121
DiseaseLung cancer

ERBB2 ERCC6

9.88e-0414992cv:C0242379
DiseaseLUNG CANCER

ERBB2 ERCC6

9.88e-0414992211980
Diseaserenal cell carcinoma (biomarker_via_orthology)

ANXA2 ANXA2P2

9.88e-0414992DOID:4450 (biomarker_via_orthology)
Diseaseovarian neoplasm

ERBB2 ERCC6 CAMKK2 EPCAM

1.10e-03134994C0919267
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH7 MYH15

1.14e-0315992DOID:0050646 (implicated_via_orthology)
DiseaseAutosomal Recessive Centronuclear Myopathy

MYH7 RYR1

1.14e-0315992C3645536
DiseaseMalignant neoplasm of ovary

ERBB2 ERCC6 CAMKK2 EPCAM

1.19e-03137994C1140680
Diseaselung non-small cell carcinoma (is_implicated_in)

ERCC6 FAT1 PLCG1 IL1A

1.26e-03139994DOID:3908 (is_implicated_in)
Diseaseeicosapentaenoate EPA; 20:5n3 measurement

CDK14 FZD1

1.47e-0317992EFO_0021049
DiseaseCongenital Fiber Type Disproportion

MYH7 RYR1

1.65e-0318992C0546264
Diseasecardiomyopathy (implicated_via_orthology)

ERBB2 MYH7 MYH15

1.77e-0371993DOID:0050700 (implicated_via_orthology)
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

ERBB2 PLCG1

1.84e-0319992DOID:2876 (is_marker_for)
DiseaseLung Neoplasms

ERBB2 ERCC6 ANXA2 GCLC NOTCH2

2.03e-03265995C0024121
DiseaseMalignant neoplasm of lung

ERBB2 ERCC6 ANXA2 GCLC NOTCH2

2.06e-03266995C0242379
DiseaseGlioblastoma

FAT1 POLK NOTCH2

2.41e-0379993C0017636
Diseasehypothyroidism (biomarker_via_orthology)

MYH7 ANXA2 ANXA2P2

2.50e-0380993DOID:1459 (biomarker_via_orthology)
Diseasedilated cardiomyopathy (implicated_via_orthology)

ERBB2 MYH7 MYH15

2.50e-0380993DOID:12930 (implicated_via_orthology)
DiseaseCarcinoma of lung

ERBB2 ERCC6

2.69e-0323992C0684249
DiseaseGiant Cell Glioblastoma

FAT1 POLK NOTCH2

2.87e-0384993C0334588
Diseaseuveitis (biomarker_via_orthology)

TJP1 IL1A

3.18e-0325992DOID:13141 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
ILKDLMKTAGTAKVR

AHSA2P

131

Q719I0
QMRILKETELRKVKV

ERBB2

711

P04626
AGIVVLVISRKKRMA

EPCAM

281

P16422
GKVMRRLLRKIITSE

ACSS1

641

Q9NUB1
AAIVDKVLSMRIVKK

CHD8

641

Q9HCK8
LTRIGVMSLVRKKVQ

CHD5

1501

Q8TDI0
MKRGSRKGSIEIKKI

BMX

46

P51813
LRVEKRLKTKAVRMI

GPR17

251

Q13304
TVDKLKMLEGRKTSI

BRPF3

1161

Q9ULD4
KMLEGRKTSIRKSVQ

BRPF3

1166

Q9ULD4
KKMRILILSLDTAGK

ARL17A

16

Q8IVW1
KGTRDKVLIRIMVSR

ANXA2

281

P07355
VKTLLLKMKRVLQES

CCSER1

631

Q9C0I3
EKIGKMKKLRRTLSE

CDK14

11

O94921
TQAKLLAKKRVVRML

CCKBR

321

P32239
KGTRDKVLIRIMVSR

ANXA2P2

281

A6NMY6
MEVIRLKGLVSIKDK

CBWD5

311

Q5RIA9
KRSGKMIVVESLLKI

ERCC6

836

Q03468
TLVLGVLRMAKKRVI

ATP2C2

346

O75185
KLVRSKLKAMTLAIG

ATP10A

1016

O60312
MTGRILDLKTGTVKK

ARNT2

206

Q9HBZ2
MTSRKKVLLKVIILG

RAB7A

1

P51149
VRLDGTMSIKKRAKV

RAD54L

541

Q92698
SVKGMRKSERRIKEL

MYH7

1836

P12883
RQVETKVRAKIRKMK

NPIPA1

111

Q9UND3
VVVFVLCRKMISRKK

FAT1

4196

Q14517
FIILLGVIMAKRKRK

NOTCH2

1691

Q04721
MVVVATNGKVLKKRR

IL1A

71

P01583
KQMETRKRLAKIVLV

NMBR

256

P28336
DIRKKVRRLMGKSHI

MADD

1391

Q8WXG6
DRKMVRIVLTKTKRD

NUDCD2

81

Q8WVJ2
TVILVKSMLRKRSFG

CAMKK1

446

Q8N5S9
MEVIRLKGLVSIKDK

CBWD2

311

Q8IUF1
MEVIRLKGLVSIKDK

CBWD1

311

Q9BRT8
MLNAIRRGVKLKKTT

MTSS1

731

O43312
MKTTVKRGLVLRNEK

PFKM

616

P08237
MQELLRSKKRKLVVI

GANC

421

Q8TET4
LIKKRASGELMTVAR

GCLC

561

P48506
RKTGRDVAIKVIDKM

PRKD3

596

O94806
RKMERLAKKGRTIVK

KMT2B

1011

Q9UMN6
MSGKRKRVVLTIKDK

JRKL

1

Q9Y4A0
KRKTTETLIILSRIM

MS4A5

106

Q9H3V2
QRKILMTLTVKVLGA

PLCG2

1056

P16885
KLRLIDTLRMVTEGK

PSMD12

121

O00232
LVTLGKVLKVIVVMR

MED27

191

Q6P2C8
LLVKIRSGKKRTVEM

HK1

541

P19367
VGLSVMSIKKKARRI

OSBPL6

136

Q9BZF3
RKKTKTVKMIGVLTL

ABCB4

31

P21439
KRKRAIKLIVTVLAM

F2RL1

281

P55085
LSTVLKRLKEIMEGK

PIKFYVE

131

Q9Y2I7
KTEKLEKLMVRIGVF

FZD1

526

Q9UP38
KTDKLERLMVKIGVF

FZD4

426

Q9ULV1
KMVNGRKITTKRIVE

DNAJB6

196

O75190
EILRKKIMEIGISQK

BTBD8

131

Q5XKL5
LTVVTIDRMLERLKK

DNAH7

1031

Q8WXX0
RLTALRIKKTLAKMV

BMPR1A

511

P36894
MEVIRLKGLVSIKDK

CBWD3

311

Q5JTY5
MEVIRLKGLVSIKDK

CBWD6

311

Q4V339
LATVILVKTMIRKRS

CAMKK2

481

Q96RR4
LIVKMIGKVLGRKHT

SLC2A9

126

Q9NRM0
ISRAKMILITKAAIK

SCAF4

21

O95104
SRLMSLLEKVRLVKK

RYR1

2061

P21817
MEKIVKERKTSSRIR

EIF4G3

956

O43432
SLDRRTGMLTVVKKL

PCDH11Y

546

Q9BZA8
RSSGKLVAVKKMDLR

PAK4

341

O96013
RQVETKVRAKIRKMK

NPIPA7

111

E9PJI5
RQVETKVRAKIRKMK

NPIPA8

111

P0DM63
IAKAMRLKISKRRVS

POLR1E

371

Q9GZS1
MVKKRKGRVVIDSDT

RTF1

41

Q92541
MTAKEGRKKSIRVLV

MRPS5

231

P82675
VRKEIVSKLMRSLKR

TRMT5

101

Q32P41
KEMKRKILLDVARTS

CCT6B

141

Q92526
GVRKTALAIKIMEKI

SLFN14

596

P0C7P3
VLGDIKRLMLSVRKL

SAMD8

61

Q96LT4
RQVETKVRAKIRKMK

NPIPA5

111

E9PKD4
SKEGLIERTERMKKT

MRPL45

101

Q9BRJ2
SRSLMIKTKKLIIDV

IQGAP2

1296

Q13576
EAKSRIEVTRLKKKM

MYH15

1616

Q9Y2K3
RGETIKMTITLKREL

PIWIL4

181

Q7Z3Z4
GLKMKAKRRRVSLVL

SPDYE10

91

P0DUX0
GLKMKAKRRRVSLVL

SPDYE11

91

P0DTA3
GLKMKAKRRRVSLVL

SPDYE8

91

P0DUD1
MKEILLKAVKRRKGS

MAPKAP1

301

Q9BPZ7
VEITLERTKMTKGIK

SPATA16

56

Q9BXB7
KEAGTETVMRILLKK

MTRES1

196

Q9P0P8
KMQKTAKVRVTRLVL

MRPS17

21

Q9Y2R5
KQSRKLRVGDIVMVK

ATP11A

141

P98196
LGSLIFEKEIKMRIK

STK31

166

Q9BXU1
LTGKVIKRDVMTRDL

RNF213

2336

Q63HN8
MLGKRKRVVLTIKDK

TIGD2

1

Q4W5G0
RELLKEVKMSGTIVK

USP16

221

Q9Y5T5
REKLKKMKTGRSALV

REV1

386

Q9UBZ9
GLKMKAKRRRVSLVL

SPDYE12

91

P0DUX1
GLKMKAKRRRVSLVL

SPDYE13

91

A0A494C0Z2
GLKMKAKRRRVSLVL

SPDYE14

91

P0DUD3
GLKMKAKRRRVSLVL

SPDYE15

91

P0DUD4
GLKMKAKRRRVSLVL

SPDYE17

91

P0DUD2
GLKMKAKRRRVSLVL

SPDYE3

156

A6NKU9
KSRKKMCILVLVLSV

STX12

246

Q86Y82
RRQIIGTKIKEGKVM

MID1

276

O15344
GTKIKEGKVMRLRKL

MID1

281

O15344
IRKVSGIGKVTEKML

POLK

351

Q9UBT6
VKRLLKKQVVRIMSC

UBE2O

386

Q9C0C9
RLMKITGLTKGEIKK

ZHX1

496

Q9UKY1
RLTEGKIMERRKKIA

PLCG1

936

P19174
LICRLKLMKTDRIVG

THNSL1

161

Q8IYQ7
ETKGRAKIRKMKVTT

NPIPB2

131

A6NJ64
TQMIKLKRGTKGLVR

PLCH1

26

Q4KWH8
VIVELIKSKKMAGRA

RUVBL1

51

Q9Y265
GKRTIMKLEARIKEL

MYH16

971

Q9H6N6
TIKMRKETEARKVVL

TMEM209

16

Q96SK2
KSRAAERKRIIIKME

ZBTB1

316

Q9Y2K1
KTLIERSKGKLKMVV

TJP1

246

Q07157
GLKMKAKRRRVSLVL

SPDYE9

91

A0A494C191
VKIGDLKRTKMVRTI

UBR4

3576

Q5T4S7
KLGKMKTRTLSTEII

TPRKB

66

Q9Y3C4
VRLTMKKGTIVKKLL

HECTD3

281

Q5T447
MKKLTTLSRRVVKVL

LIPK

211

Q5VXJ0