Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	semaphorin receptor complex	PLXNA3 ERBB2 PLXNC1	4.46e-05	13	115	3	GO:0002116
Domain	EGF	PCSK5 STAB2 DLL4 NTNG1 TECTA ITGB5 HHIP SCUBE1 OIT3 JAG1 ADGRE1	2.04e-07	235	114	11	SM00181
Domain	DUF4195	ZNF280D ZNF280C ZNF280B	8.82e-07	4	114	3	IPR025243
Domain	DUF4195	ZNF280D ZNF280C ZNF280B	8.82e-07	4	114	3	PF13836
Domain	EGF-like_dom	PCSK5 STAB2 DLL4 NTNG1 TECTA HHIP SCUBE1 OIT3 JAG1 ADGRE1	2.99e-06	249	114	10	IPR000742
Domain	Znf_C2H2-like	RAG1 ZNF280D MATR3 KCMF1 ZNF280C TRPS1 ZNF507 ZNF280B ZNF581 ZBTB1 ZBTB49 ZNF526 ZNF530 ZBTB40 ZNF239 ZNF646	2.65e-05	796	114	16	IPR015880
Domain	EGF_1	STAB2 DLL4 NTNG1 ITGB5 HHIP SCUBE1 OIT3 JAG1 ADGRE1	2.67e-05	255	114	9	PS00022
Domain	ZnF_C2H2	RAG1 ZNF280D MATR3 KCMF1 ZNF280C TRPS1 ZNF507 ZNF280B ZNF581 ZBTB1 ZBTB49 ZNF526 ZNF530 ZBTB40 ZNF239 ZNF646	3.17e-05	808	114	16	SM00355
Domain	EGF_extracell	STAB2 DLL4 ITGB5 HHIP JAG1	3.24e-05	60	114	5	IPR013111
Domain	EGF_2	STAB2 DLL4 ITGB5 HHIP JAG1	3.24e-05	60	114	5	PF07974
Domain	EGF_2	STAB2 DLL4 NTNG1 ITGB5 HHIP SCUBE1 OIT3 JAG1 ADGRE1	3.60e-05	265	114	9	PS01186
Domain	Growth_fac_rcpt_	PCSK5 ERBB2 STAB2 DLL4 SCUBE1 JAG1 ADGRE1	4.83e-05	156	114	7	IPR009030
Domain	EGF_3	STAB2 DLL4 NTNG1 HHIP SCUBE1 OIT3 JAG1 ADGRE1	9.76e-05	235	114	8	PS50026
Domain	EGF_CA	STAB2 DLL4 SCUBE1 OIT3 JAG1 ADGRE1	1.03e-04	122	114	6	SM00179
Domain	EGF-like_Ca-bd_dom	STAB2 DLL4 SCUBE1 OIT3 JAG1 ADGRE1	1.13e-04	124	114	6	IPR001881
Domain	PLAC	PCSK5 ADAMTS12 ADAMTS10	2.00e-04	19	114	3	PS50900
Domain	PLAC	PCSK5 ADAMTS12 ADAMTS10	2.00e-04	19	114	3	IPR010909
Domain	EGF-like_CS	STAB2 DLL4 NTNG1 ITGB5 HHIP SCUBE1 JAG1 ADGRE1	2.01e-04	261	114	8	IPR013032
Domain	DSL	DLL4 JAG1	2.20e-04	4	114	2	PF01414
Domain	DSL	DLL4 JAG1	2.20e-04	4	114	2	SM00051
Domain	ZINC_FINGER_C2H2_2	ZNF280D KCMF1 ZNF280C TRPS1 ZNF507 ZNF280B ZNF581 ZBTB1 ZBTB49 ZNF526 ZNF530 ZBTB40 ZNF239 ZNF646	2.67e-04	775	114	14	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF280D KCMF1 ZNF280C TRPS1 ZNF507 ZNF280B ZNF581 ZBTB1 ZBTB49 ZNF526 ZNF530 ZBTB40 ZNF239 ZNF646	2.74e-04	777	114	14	PS00028
Domain	DSL	DLL4 JAG1	3.65e-04	5	114	2	PS51051
Domain	Notch_ligand_N	DLL4 JAG1	3.65e-04	5	114	2	IPR011651
Domain	MNNL	DLL4 JAG1	3.65e-04	5	114	2	PF07657
Domain	DSL	DLL4 JAG1	3.65e-04	5	114	2	IPR001774
Domain	ASX_HYDROXYL	DLL4 SCUBE1 OIT3 JAG1 ADGRE1	3.68e-04	100	114	5	PS00010
Domain	Znf_C2H2	ZNF280D KCMF1 ZNF280C TRPS1 ZNF507 ZNF280B ZNF581 ZBTB1 ZBTB49 ZNF526 ZNF530 ZBTB40 ZNF239 ZNF646	3.91e-04	805	114	14	IPR007087
Domain	EGF-type_Asp/Asn_hydroxyl_site	DLL4 SCUBE1 OIT3 JAG1 ADGRE1	4.81e-04	106	114	5	IPR000152
Domain	GF_recep_IV	PCSK5 ERBB2	5.45e-04	6	114	2	PF14843
Domain	GF_recep_IV	PCSK5 ERBB2	5.45e-04	6	114	2	IPR032778
Domain	EGF	STAB2 DLL4 TECTA ITGB5 JAG1	1.05e-03	126	114	5	PF00008
Domain	Plexin_cytopl	PLXNA3 PLXNC1	1.29e-03	9	114	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA3 PLXNC1	1.29e-03	9	114	2	IPR013548
Domain	Plexin	PLXNA3 PLXNC1	1.29e-03	9	114	2	IPR031148
Domain	Rho_GTPase_activation_prot	PLXNA3 GAPVD1 ARHGAP35 PLXNC1	2.07e-03	88	114	4	IPR008936
Domain	EGF_dom	STAB2 SCUBE1	2.34e-03	12	114	2	IPR024731
Domain	EGF_3	STAB2 SCUBE1	2.34e-03	12	114	2	PF12947
Domain	PSI	PLXNA3 ITGB5 PLXNC1	2.44e-03	44	114	3	IPR016201
Domain	PSI	PLXNA3 ITGB5 PLXNC1	2.78e-03	46	114	3	SM00423
Domain	EGF_Ca-bd_CS	SCUBE1 OIT3 JAG1 ADGRE1	2.95e-03	97	114	4	IPR018097
Domain	EGF_CA	SCUBE1 OIT3 JAG1 ADGRE1	3.17e-03	99	114	4	PS01187
Domain	ZP_2	TECTA OIT3	3.20e-03	14	114	2	PS51034
Domain	PLAC	PCSK5 ADAMTS10	3.20e-03	14	114	2	PF08686
Domain	ZP_1	TECTA OIT3	3.20e-03	14	114	2	PS00682
Domain	zf-C2H2	ZNF280D TRPS1 ZNF507 ZNF581 ZBTB1 ZBTB49 ZNF526 ZNF530 ZBTB40 ZNF239 ZNF646	3.42e-03	693	114	11	PF00096
Domain	Bbox_C	TRIM45 TRIM66	3.68e-03	15	114	2	IPR003649
Domain	BBC	TRIM45 TRIM66	3.68e-03	15	114	2	SM00502
Domain	ZP	TECTA OIT3	3.68e-03	15	114	2	SM00241
Domain	-	PLXNA3 GAPVD1	4.19e-03	16	114	2	1.10.506.10
Domain	ZP_dom	TECTA OIT3	4.73e-03	17	114	2	IPR001507
Domain	Zona_pellucida	TECTA OIT3	4.73e-03	17	114	2	PF00100
Domain	ZF_ZZ_2	KCMF1 HERC2	5.30e-03	18	114	2	PS50135
Domain	ZF_ZZ_1	KCMF1 HERC2	5.30e-03	18	114	2	PS01357
Domain	ZZ	KCMF1 HERC2	5.30e-03	18	114	2	PF00569
Domain	RasGAP_dom	PLXNA3 GAPVD1	5.30e-03	18	114	2	IPR001936
Domain	Furin_repeat	PCSK5 ERBB2	5.30e-03	18	114	2	IPR006212
Domain	FU	PCSK5 ERBB2	5.30e-03	18	114	2	SM00261
Domain	VWC_out	TECTA JAG1	5.90e-03	19	114	2	SM00215
Domain	Znf_ZZ	KCMF1 HERC2	5.90e-03	19	114	2	IPR000433
Domain	ZnF_ZZ	KCMF1 HERC2	5.90e-03	19	114	2	SM00291
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HAUS6 GNB1L NTNG1 RNF213 ARHGAP35 EFTUD2 TRIM66 RFTN1 ZNF526 VPS13D PER3 MACF1	1.05e-07	493	116	12	15368895
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NRIP1 ZFAND3 ERBB2 KIF1B TRPS1 RNF213 ARHGAP35 TECTA ITGB5 SFMBT2 BMPR1B RIC8B GUCY1A1 SUPT6H USP40 NLRC5 MACF1 AKAP13 C1orf159 ANKRD12	1.05e-07	1489	116	20	28611215
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	PLXNA3 POLR3K ZNF280D KCMF1 ZNF280C TRPS1 ZNF507 ZNF280B PER3 PLXNC1 SMAD1 ZNF239 ZNF646	3.19e-06	808	116	13	20412781
Pubmed	The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition.	DLL4 JAG1 ADGRE1	5.85e-06	11	116	3	34910918
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MIIP MAPKAP1 ERBB2 GAPVD1 DSG2 MATR3 KIF1B STIL EDC4 VPS13D MACF1 AKAP13 UVRAG	6.32e-06	861	116	13	36931259
Pubmed	Expression and functional roles of Smad1 and BMPR-IB in glioma development.	BMPR1B SMAD1	1.10e-05	2	116	2	19513897
Pubmed	The expression profile of Jagged1 and Delta-like 4 in hepatocellular carcinoma.	DLL4 JAG1	1.10e-05	2	116	2	30660174
Pubmed	HER2Δ16 Engages ENPP1 to Promote an Immune-Cold Microenvironment in Breast Cancer.	ERBB2 ENPP1	1.10e-05	2	116	2	37311021
Pubmed	KSHV manipulates Notch signaling by DLL4 and JAG1 to alter cell cycle genes in lymphatic endothelia.	DLL4 JAG1	1.10e-05	2	116	2	19816565
Pubmed	The clinicopathological significance of Jagged1 and DLL4 in gallbladder cancer.	DLL4 JAG1	1.10e-05	2	116	2	27174628
Pubmed	The Vascular Notch Ligands Delta-Like Ligand 4 (DLL4) and Jagged1 (JAG1) Have Opposing Correlations with Microvascularization but a Uniform Prognostic Effect in Primary Glioblastoma: A Preliminary Study.	DLL4 JAG1	1.10e-05	2	116	2	26546995
Pubmed	Tumor-derived Jagged1 promotes cancer progression through immune evasion.	RAG1 JAG1	1.10e-05	2	116	2	35263601
Pubmed	Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth.	DLL4 JAG1	1.10e-05	2	116	2	28445154
Pubmed	Recruitment of trimeric eIF2 by phosphatase non-catalytic subunit PPP1R15B.	PPP1R15B EIF2S2	1.10e-05	2	116	2	38159565
Pubmed	Distinct gene expression profiles associated with Notch ligands Delta-like 4 and Jagged1 in plaque material from peripheral artery disease patients: a pilot study.	DLL4 JAG1	1.10e-05	2	116	2	28472949
Pubmed	[CHANGES OF THE CONTENT OF DLL4 AND Jag-1 ANGIOGENESIS REGULATORS IN HUMAN DERMIS IN ONTOGENESIS].	DLL4 JAG1	1.10e-05	2	116	2	27487663
Pubmed	Jagged1 and DLL4 expressions in benign and malignant pancreatic lesions and their clinicopathological significance.	DLL4 JAG1	1.10e-05	2	116	2	27919854
Pubmed	Plasma factor XIII binds specifically to fibrinogen molecules containing gamma chains.	F13B FGG	1.10e-05	2	116	2	8756701
Pubmed	Expression of vascular Notch ligands Delta-like 4 and Jagged-1 in glioblastoma.	DLL4 JAG1	1.10e-05	2	116	2	22296176
Pubmed	Endothelial Jagged1 antagonizes Dll4 regulation of endothelial branching and promotes vascular maturation downstream of Dll4/Notch1.	DLL4 JAG1	1.10e-05	2	116	2	25767274
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	NRIP1 HAUS6 GAPVD1 ZNF280D TRPS1 ZNF507 ZBTB1 SFMBT2 BRCA2	1.18e-05	418	116	9	34709266
Pubmed	Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation.	RAG1 BMPR1B SMAD1	1.28e-05	14	116	3	12421925
Pubmed	Endothelial Jarid2/Jumonji is required for normal cardiac development and proper Notch1 expression.	ERBB2 DLL4 JAG1	1.28e-05	14	116	3	21402699
Pubmed	BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling.	BMPR1B JAG1 SMAD1	1.60e-05	15	116	3	16324690
Pubmed	Genetic variations strongly influence phenotypic outcome in the mouse retina.	NRIP1 ITGB5 JAG1 ABCD2	1.72e-05	46	116	4	21779340
Pubmed	Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation.	DLL4 HHIP JAG1 SMAD1	1.88e-05	47	116	4	32747435
Pubmed	Impairment of endothelial-mesenchymal transformation during atrioventricular cushion formation in Tmem100 null embryos.	DLL4 JAG1 SMAD1	1.96e-05	16	116	3	25318679
Pubmed	BMP signaling is necessary for patterning the sensory and nonsensory regions of the developing mammalian cochlea.	BMPR1B JAG1 SMAD1	2.38e-05	17	116	3	21068310
Pubmed	SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling.	BMPR1B SCUBE1 SMAD1	2.84e-05	18	116	3	33308444
Pubmed	Association of Germline Genetic Testing Results With Locoregional and Systemic Therapy in Patients With Breast Cancer.	ERBB2 BRCA2	3.30e-05	3	116	2	32027353
Pubmed	Interleukin-23 drives intestinal inflammation through direct activity on T cells.	RAG1 IL23R	3.30e-05	3	116	2	20732640
Pubmed	SerpinB1 controls encephalitogenic T helper cells in neuroinflammation.	RAG1 IL23R	3.30e-05	3	116	2	31548399
Pubmed	Inhibition of HER2 Increases JAGGED1-dependent Breast Cancer Stem Cells: Role for Membrane JAGGED1.	ERBB2 JAG1	3.30e-05	3	116	2	29895705
Pubmed	DLL4 and Jagged1 are angiogenic targets of orphan nuclear receptor TR3/Nur77.	DLL4 JAG1	3.30e-05	3	116	2	30930165
Pubmed	Clinicopathological features and BRCA1 and BRCA2 mutation status in a prospective cohort of young women with breast cancer.	ERBB2 BRCA2	3.30e-05	3	116	2	34703009
Pubmed	Notch exhibits ligand bias and maneuvers stage-specific steering of neural differentiation in embryonic stem cells.	DLL4 JAG1	3.30e-05	3	116	2	20154142
Pubmed	PKCα Attenuates Jagged-1-Mediated Notch Signaling in ErbB-2-Positive Breast Cancer to Reverse Trastuzumab Resistance.	ERBB2 JAG1	3.30e-05	3	116	2	26350262
Pubmed	The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90.	RAG1 IL23R	3.30e-05	3	116	2	23202271
Pubmed	ZBTB1 is a determinant of lymphoid development.	RAG1 ZBTB1	3.30e-05	3	116	2	22201126
Pubmed	Notch ligands, Delta-1 and Delta-4 suppress the self-renewal capacity and long-term growth of two myeloblastic leukemia cell lines.	DLL4 JAG1	3.30e-05	3	116	2	12684674
Pubmed	Cross talk between engulfment receptors stabilin-2 and integrin αvβ5 orchestrates engulfment of phosphatidylserine-exposed erythrocytes.	STAB2 ITGB5	3.30e-05	3	116	2	22566688
Pubmed	Hexokinase 2-mediated Warburg effect is required for PTEN- and p53-deficiency-driven prostate cancer growth.	HK2 BRCA2	3.30e-05	3	116	2	25176644
Pubmed	New insights into the genetic basis of premature ovarian insufficiency: Novel causative variants and candidate genes revealed by genomic sequencing.	NRIP1 MACF1	3.30e-05	3	116	2	33036707
Pubmed	DOCK8 regulates protective immunity by controlling the function and survival of RORγt+ ILCs.	RAG1 IL23R	3.30e-05	3	116	2	25091235
Pubmed	A novel tumor suppressor ZBTB1 regulates tamoxifen resistance and aerobic glycolysis through suppressing HER2 expression in breast cancer.	ERBB2 ZBTB1	3.30e-05	3	116	2	32690611
Pubmed	Zinc Finger 280B regulates sGCα1 and p53 in prostate cancer cells.	ZNF280B GUCY1A1	3.30e-05	3	116	2	24236047
Pubmed	Purinergic receptor P2Y12 boosts autoimmune hepatitis through hexokinase 2-dependent glycolysis in T cells.	RAG1 HK2	3.30e-05	3	116	2	37497007
Pubmed	Low prevalence of HER2 positivity amongst BRCA1 and BRCA2 mutation carriers and in primary BRCA screens.	ERBB2 BRCA2	3.30e-05	3	116	2	26888723
Pubmed	The interaction between fibrinogen and zymogen FXIII-A2B2 is mediated by fibrinogen residues γ390-396 and the FXIII-B subunits.	F13B FGG	3.30e-05	3	116	2	27561317
Pubmed	Prevalence of germline BRCA mutations in HER2-negative metastatic breast cancer: global results from the real-world, observational BREAKOUT study.	ERBB2 BRCA2	3.30e-05	3	116	2	33109210
Pubmed	A role for ErbB signaling in the induction of reactive astrogliosis.	ERBB2 MLC1	3.30e-05	3	116	2	29238610
Pubmed	Sequential Ligand-Dependent Notch Signaling Activation Regulates Valve Primordium Formation and Morphogenesis.	DLL4 JAG1 SMAD1	3.37e-05	19	116	3	27056911
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	MAPKAP1 HAUS6 HK2 DLL4 MATR3 KCMF1 EDC4 METTL23 ITGB5 HNRNPK TRAPPC13 ZBTB49 EIF2S2 ZBTB40 PPIL2	3.64e-05	1327	116	15	32694731
Pubmed	Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.	DLL4 BMPR1B JAG1	6.10e-05	23	116	3	14701881
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	ZNF280D ZNF280C TRPS1 ZNF280B ZBTB1	6.45e-05	125	116	5	32891193
Pubmed	The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis.	DLL4 JAG1	6.59e-05	4	116	2	19524514
Pubmed	IkappaB kinase alpha kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells.	RAG1 ERBB2	6.59e-05	4	116	2	17890319
Pubmed	Association of BRCA1, BRCA2, RAD51, and HER2 gene polymorphisms with the breast cancer risk in the Bangladeshi population.	ERBB2 BRCA2	6.59e-05	4	116	2	27068824
Pubmed	Phenotypic analysis of familial breast cancer: comparison of BRCAx tumors with BRCA1-, BRCA2-carriers and non-familial breast cancer.	ERBB2 BRCA2	6.59e-05	4	116	2	25736863
Pubmed	Notch1 and Notch4 core binding domain peptibodies exhibit distinct ligand-binding and anti-angiogenic properties.	DLL4 JAG1	6.59e-05	4	116	2	36376768
Pubmed	Notch ligands transduce different magnitudes of signaling critical for determination of T-cell fate.	DLL4 JAG1	6.59e-05	4	116	2	20602435
Pubmed	Inflammatory Th17 Cells Express Integrin αvβ3 for Pathogenic Function.	RAG1 IL23R	6.59e-05	4	116	2	27452457
Pubmed	No evidence for a functional role of bi-directional Notch signaling during angiogenesis.	DLL4 JAG1	6.59e-05	4	116	2	23300864
Pubmed	Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2.	PCSK5 VEGFD	6.59e-05	4	116	2	17242158
Pubmed	Hierarchies in the binding of human factor XIII, factor XIIIa, and endothelial cell transglutaminase to human plasma fibrinogen, fibrin, and fibronectin.	F13B FGG	6.59e-05	4	116	2	8905624
Pubmed	Tissue-intrinsic dysfunction of circadian clock confers transplant arteriosclerosis.	RAG1 PER3	6.59e-05	4	116	2	21969583
Pubmed	Combination DLL4 with Jagged1-siRNA can enhance inhibition of the proliferation and invasiveness activity of human gastric carcinoma by Notch1/VEGF pathway.	DLL4 JAG1	6.59e-05	4	116	2	22020917
Pubmed	Mechanical regulation of cancer cell apoptosis and autophagy: roles of bone morphogenetic protein receptor, Smad1/5, and p38 MAPK.	BMPR1B SMAD1	6.59e-05	4	116	2	24021264
Pubmed	Loss of Gata5 in mice leads to bicuspid aortic valve.	ERBB2 DLL4 JAG1	6.95e-05	24	116	3	21633169
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GAPVD1 HK2 ZNF280D DSG2 MATR3 GNB1L ZNF280C EDC4 RFC3 HNRNPK EFTUD2 RIC8B GAR1 SUPT6H EIF2S2	8.11e-05	1425	116	15	30948266
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PCSK5 PLXNA3 ERBB2 EDC4 ARHGAP35 CIT ITGB5 PPP1R15B USP40 NLRC5 AKAP13 HERC2 UVRAG	8.38e-05	1105	116	13	35748872
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	HK2 PPP1R15B EIF2S2	8.89e-05	26	116	3	18500982
Pubmed	Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye.	BMPR1B JAG1 SMAD1	9.97e-05	27	116	3	23676271
Pubmed	Notch signaling is essential for ventricular chamber development.	ERBB2 DLL4 SMAD1	9.97e-05	27	116	3	17336907
Pubmed	The Ube2m-Rbx1 neddylation-Cullin-RING-Ligase proteins are essential for the maintenance of Regulatory T cell fitness.	RAG1 UBE2F	1.10e-04	5	116	2	35641500
Pubmed	Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling.	RAG1 IL23R	1.10e-04	5	116	2	36070768
Pubmed	Trps1 plays a pivotal role downstream of Gdf5 signaling in promoting chondrogenesis and apoptosis of ATDC5 cells.	TRPS1 BMPR1B	1.10e-04	5	116	2	18363966
Pubmed	Mutual regulation of follicle-stimulating hormone signaling and bone morphogenetic protein system in human granulosa cells.	BMPR1B SMAD1	1.10e-04	5	116	2	16436528
Pubmed	The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation.	RAG1 IL23R	1.10e-04	5	116	2	24586521
Pubmed	Notch signal strength controls cell fate in the haemogenic endothelium.	DLL4 JAG1	1.10e-04	5	116	2	26465397
Pubmed	Two distinct Notch signals, Delta-like 4/Notch1 and Jagged-1/Notch2, antagonistically regulate chemical hepatocarcinogenesis in mice.	DLL4 JAG1	1.10e-04	5	116	2	35064244
Pubmed	Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads.	BMPR1B SMAD1	1.10e-04	5	116	2	11483516
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	MATR3 ARHGAP35 CIT HNRNPK MACF1 FGG	1.30e-04	231	116	6	16452087
Pubmed	Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy.	DSG2 ADGRE1 SMAD1	1.37e-04	30	116	3	21880664
Pubmed	Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.	MBL2 CPED1 JAG1 ZBTB40	1.46e-04	79	116	4	22504420
Pubmed	BMP/SMAD signaling regulates the cell behaviors that drive the initial dorsal-specific regional morphogenesis of the otocyst.	BMPR1B SMAD1	1.64e-04	6	116	2	20837004
Pubmed	Aluminum adjuvants elicit fibrin-dependent extracellular traps in vivo.	RAG1 FGG	1.64e-04	6	116	2	20876456
Pubmed	Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation.	BMPR1B SMAD1	1.64e-04	6	116	2	12151307
Pubmed	Plasmin-mediated fibrinolysis enables macrophage migration in a murine model of inflammation.	F13B FGG	1.64e-04	6	116	2	31101623
Pubmed	A study on Notch signaling in human breast cancer.	DLL4 JAG1	1.64e-04	6	116	2	17822320
Pubmed	Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression.	BMPR1B SMAD1	1.64e-04	6	116	2	16604073
Pubmed	NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.	RAG1 HK2	1.64e-04	6	116	2	33398181
Pubmed	Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches.	DLL4 JAG1	1.64e-04	6	116	2	19217325
Pubmed	Notch4 reveals a novel mechanism regulating Notch signal transduction.	DLL4 JAG1	1.64e-04	6	116	2	24667410
Pubmed	p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling.	ERBB2 BRCA2	1.64e-04	6	116	2	16951165
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	GAPVD1 DSG2 MATR3 EDC4 RFC3 CIT HNRNPK EFTUD2 GAR1 SUPT6H MACF1 HERC2	1.65e-04	1024	116	12	24711643
Pubmed	Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis.	DLL4 JAG1 SMAD1	2.01e-04	34	116	3	21311046
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	CFAP251 MATR3 SFMBT2 HNRNPK ASXL3 MACF1 AKAP13	2.17e-04	361	116	7	26167880
Pubmed	The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina.	DLL4 ITGB5 JAG1	2.19e-04	35	116	3	28402857
Pubmed	An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart.	BMP2K BMPR1B SMAD1	2.19e-04	35	116	3	18832392
Cytoband	12q23.3	STAB2 RIC8B PLXNC1	9.70e-05	35	116	3	12q23.3
GeneFamily	Plexins	PLXNA3 PLXNC1	6.99e-04	9	81	2	683
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	TRPS1 ZNF507 ZNF581 ZBTB1 ZBTB49 ZNF526 ZNF530 ZBTB40 ZNF239 ZNF646	1.35e-03	718	81	10	28
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	PCSK5 HAUS6 HK2 TRPS1 RNF213 CPED1 ITGB5 HHIP LRRN3 SCUBE1 BRCA2 GUCY1A1 PLXNC1 ASXL3 JAG1 USP40 VEGFD	7.26e-07	768	114	17	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500	HK2 TRPS1 RNF213 CPED1 ITGB5 HHIP LRRN3 SCUBE1 GUCY1A1 PLXNC1 VEGFD	4.30e-06	364	114	11	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	PCSK5 NRIP1 GAPVD1 ZNF280D ENPP1 MATR3 KIF1B TRPS1 LRRN3 NOTUM GUCY1A1 ASXL3 PCDH19 USP40 ANKRD12 ADGRE1	5.91e-06	801	114	16	gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_200	RNF213 CPED1 HHIP SCUBE1 GUCY1A1 PLXNC1 VEGFD	9.70e-06	138	114	7	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_200
CoexpressionAtlas	kidney_e10.5_UretericTip_HoxB7_k-means-cluster#4_top-relative-expression-ranked_1000	POLR3K HAUS6 ZNF280C TRPS1 STIL BMPR1B GAR1 PUS10 JAG1 EIF2S2	1.85e-05	348	114	10	gudmap_kidney_e10.5_UretericTip_HoxB7_k4_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500	TRPS1 RNF213 CPED1 HHIP LRRN3 SCUBE1 GUCY1A1 PLXNC1 JAG1 VEGFD	2.25e-05	356	114	10	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_100	CPED1 HHIP GUCY1A1 PLXNC1 VEGFD	3.25e-05	68	114	5	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_100
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#3	ZNF280D TRPS1 NTNG1 DGKB RNF213 STIL RFC3 ITGB5 ADAMTS10 BRCA2 ASXL3 MACF1 AKAP13 ANKRD12 VEGFD	4.01e-05	834	114	15	Facebase_RNAseq_e10.5_Mandibular Arch_2500_K3
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_100	CPED1 HHIP GUCY1A1 VEGFD	4.54e-05	37	114	4	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_100
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_100	CPED1 HHIP GUCY1A1 PLXNC1 VEGFD	4.59e-05	73	114	5	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_100
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_100	CPED1 HHIP GUCY1A1 PLXNC1 VEGFD	5.57e-05	76	114	5	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_100
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_100	CPED1 HHIP GUCY1A1 PLXNC1 VEGFD	6.31e-05	78	114	5	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_100
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500	PCSK5 ZNF280D TRPS1 NTNG1 CPED1 CIT SCUBE1 BRCA2 ASXL3 PCDH19 MACF1	6.95e-05	492	114	11	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	PCSK5 TRPS1 NTNG1 RNF213 CPED1 ITGB5 HHIP LRRN3 SCUBE1 GUCY1A1 PLXNC1 ASXL3 JAG1 VEGFD	7.26e-05	777	114	14	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#5	ZNF280D TRPS1 NTNG1 RNF213 STIL RFC3 BRCA2 ASXL3 VEGFD	7.53e-05	331	114	9	Facebase_RNAseq_e10.5_Mandibular Arch_1000_K5
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500	HK2 TRPS1 RNF213 CPED1 ADAMTS12 SCUBE1 GUCY1A1 PLXNC1 ASXL3 VEGFD	8.65e-05	418	114	10	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500	TRPS1 CPED1 ADAMTS12 SCUBE1 GUCY1A1 ASXL3 VEGFD	1.29e-04	207	114	7	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200	CPED1 HHIP SCUBE1 GUCY1A1 PLXNC1 VEGFD	1.38e-04	146	114	6	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	ERBB2 HK2 TRPS1 RNF213 CPED1 ZBTB1 ITGB5 ADAMTS12 SCUBE1 GUCY1A1 PLXNC1 ASXL3 USP40 VEGFD	1.40e-04	827	114	14	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200	CPED1 HHIP SCUBE1 GUCY1A1 PLXNC1 VEGFD	1.43e-04	147	114	6	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_200
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200	CPED1 HHIP SCUBE1 GUCY1A1 PLXNC1 VEGFD	1.78e-04	153	114	6	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_200
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#1_top-relative-expression-ranked_1000	NRIP1 ZNF280D LRRN3 NOTUM ASXL3	1.95e-04	99	114	5	gudmap_developingGonad_e14.5_ epididymis_1000_k1
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500	NTNG1 CPED1 HHIP LRRN3 GUCY1A1 VEGFD	1.98e-04	156	114	6	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_1000	ERBB2 HK2 ZBTB1 ITGB5 PLXNC1	2.46e-04	104	114	5	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_100	CPED1 HHIP VEGFD	2.81e-04	24	114	3	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k3_100
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_200	CPED1 HHIP GUCY1A1 VEGFD	2.86e-04	59	114	4	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_200
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	PCSK5 NRIP1 GAPVD1 ENPP1 KIF1B TRPS1 CIT HHIP VPS13D ASXL3 USP40 ANKRD12 ADGRE1	3.23e-04	790	114	13	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000	NRIP1 GAPVD1 ZNF280D MATR3 KIF1B TRPS1 RNF213 CIT PLXNC1 ASXL3 EIF2S2 USP40 ANKRD12	3.81e-04	804	114	13	gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlas	kidney_e15.5_Podocyte_MafB_k-means-cluster#3_top-relative-expression-ranked_1000	TRPS1 CPED1 ZBTB1 BMPR1B GAR1 PUS10 JAG1	3.97e-04	249	114	7	gudmap_kidney_e15.5_Podocyte_MafB_k3_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_200	CPED1 HHIP VEGFD	4.01e-04	27	114	3	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_200
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5	POLR3K ZNF280D ZNF507 NTNG1 ARHGAP35 CIT ZBTB1 BRCA2 SUPT6H EIF2S2 MACF1	5.75e-04	629	114	11	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#2_top-relative-expression-ranked_1000	DSG2 RNF213 ZBTB1 SCUBE1 PLXNC1	5.95e-04	126	114	5	gudmap_dev gonad_e11.5_F_GonMes_Sma_k2_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4	ZNF280D CIT SCUBE1 BRCA2 PCDH19 MACF1	6.00e-04	192	114	6	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000	HK2 DSG2 TRPS1 RNF213 STIL RFC3 ZBTB1 ITGB5 ADAMTS12 SCUBE1 GUCY1A1 PLXNC1 ASXL3	6.36e-04	849	114	13	gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	TRPS1 NTNG1 RNF213 STIL ITGB5 BRCA2 ASXL3 EIF2S2 MACF1 AKAP13 ANKRD12 VEGFD	6.60e-04	744	114	12	Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K4
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500	CPED1 HHIP LRRN3 GUCY1A1 VEGFD	6.86e-04	130	114	5	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500	NTNG1 CPED1 HHIP LRRN3 SCUBE1 GUCY1A1 PLXNC1 VEGFD	7.44e-04	361	114	8	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#3	PCSK5 TRPS1 NTNG1 CPED1 ASXL3	7.86e-04	134	114	5	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K3
ToppCell	10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3\|bone_marrow / Manually curated celltypes from each tissue	DSG2 ENPP1 TRIM45 JAG1 KCNS3 IL23R ZNF646	1.71e-07	155	116	7	83430a64c2cb5ad29caa3dacba76c28dd204ac40
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	STIL RFC3 CPED1 CIT HHIP BRCA2 NOTUM	6.78e-07	190	116	7	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	MIIP ZNF507 SFMBT2 BMPR1B PER3 AKAP13	4.25e-06	162	116	6	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HK2 HHIP NOTUM PLA2G1B AKAP13 FGG	4.56e-06	164	116	6	b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HK2 HHIP NOTUM PLA2G1B AKAP13 FGG	4.56e-06	164	116	6	3aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RFC3 CPED1 HHIP MIXL1 MACF1 VEGFD	5.60e-06	170	116	6	e20568c8f3f17d94de78229617eb2f7e4c5af2bc
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK2 BMP2K ITGB5 MACF1 AKAP13 FGG	6.62e-06	175	116	6	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RFC3 CPED1 HHIP BRCA2 MACF1 VEGFD	6.84e-06	176	116	6	cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-CD45____plasma_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXNA3 ENPP1 CPED1 ADORA3 LRRN3 JCHAIN	7.06e-06	177	116	6	41cbb2c109eaa7be366fc0510cce64abc06837b4
ToppCell	RV-11._Adipocyte\|RV / Chamber and Cluster_Paper	PCSK5 NRIP1 HK2 TRPS1 ADAMTS12 ABCD2	7.29e-06	178	116	6	278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 HK2 RDH5 BMPR1B GUCY1A1 MLC1	8.54e-06	183	116	6	25c96df8ea0c7bbedbb7699ee84ad6234d19cba8
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	NRIP1 ENPP1 GUCY1A1 JAG1 KCNS3 IL23R	8.81e-06	184	116	6	479e60f76c191253e23699c9dd7ef7efc08c59ad
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RDH5 CPED1 GAR1 GUCY1A1 MLC1 BST1	8.81e-06	184	116	6	e7b9c69fc77040c5191ad8089697051e2589c30e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 HK2 RDH5 BMPR1B GUCY1A1 MLC1	9.09e-06	185	116	6	dbbd348714cd16a4948a04648e914b1e71e2a8ef
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 HK2 RDH5 BMPR1B GUCY1A1 MLC1	9.09e-06	185	116	6	bea69058afa5aa927fe15c1f8d46460562ec4dd4
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DGKB HHIP GUCY1A1 OTOGL KCNS3 ZNF239	9.37e-06	186	116	6	aa88d9573a237b2b8e6025fee31f69fbce824497
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DGKB HHIP GUCY1A1 OTOGL KCNS3 ZNF239	9.37e-06	186	116	6	ecc5acd111a6ee50d59544d1bdd7ed94e2812aae
ToppCell	facs-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DGKB HHIP GUCY1A1 OTOGL KCNS3 ZNF239	9.37e-06	186	116	6	26458ff8cad5577de4306cffa0ca69eb26940e0d
ToppCell	facs-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DGKB HHIP GUCY1A1 OTOGL KCNS3 ZNF239	9.37e-06	186	116	6	a71397efc68d2916ddc373d92cfd07be58033e1c
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 HHIP NOTUM GUCY1A1 CORIN KCNS3	9.66e-06	187	116	6	8bd635abdee5d5a12a3f7bf74eab4282e8e40741
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 HHIP NOTUM GUCY1A1 CORIN KCNS3	9.66e-06	187	116	6	3cb8cd7f7a4306ff74d1f7f9964014008ec1c6a0
ToppCell	droplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 HHIP NOTUM GUCY1A1 CORIN KCNS3	1.03e-05	189	116	6	cd42ce4aa217d0bd95e0cc0ba357bdfeb3e55a48
ToppCell	droplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 HHIP NOTUM GUCY1A1 CORIN KCNS3	1.03e-05	189	116	6	102501eee7760d5882dec41ea9d00147b3f4fb73
ToppCell	droplet-Lung-21m-Mesenchymal-myofibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 HHIP NOTUM GUCY1A1 CORIN KCNS3	1.03e-05	189	116	6	6e83bf855d4771885b60bb8992df2f9b508eef97
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	NTNG1 ADAMTS12 LRRN3 GUCY1A1 MACF1 KCNS3	1.06e-05	190	116	6	71e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CPED1 CIT HHIP BRCA2 NOTUM PLXNC1	1.16e-05	193	116	6	516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCell	control-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NRIP1 RNF213 ZNF526 TIMM9 ANKRD12 IL23R	1.23e-05	195	116	6	66959ae839eb60a573da06bdd227090ebb5bb9ed
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NTNG1 LRRN3 GUCY1A1 MACF1 KCNS3 VEGFD	1.26e-05	196	116	6	6730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NTNG1 LRRN3 GUCY1A1 MACF1 KCNS3 VEGFD	1.26e-05	196	116	6	21dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|normal_Lung / Location, Cell class and cell subclass	NTNG1 ADAMTS12 LRRN3 MACF1 KCNS3 VEGFD	1.30e-05	197	116	6	6c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DGKB RFTN1 LRRN3 GUCY1A1 JAG1 KCNS3	1.30e-05	197	116	6	6668f0da54f3bf96769275e668cd57e00b8a5ef9
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DGKB RFTN1 LRRN3 GUCY1A1 JAG1 KCNS3	1.30e-05	197	116	6	7c275a2ac24a9a4f83fceda93a067e754837102f
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NTNG1 ADAMTS12 GUCY1A1 ASXL3 MACF1 VEGFD	1.30e-05	197	116	6	11a4c417f035e554431a8f03be13b5eefa3530c0
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	ERBB2 RNF213 EDC4 MLC1 SUPT6H MACF1	1.34e-05	198	116	6	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	NTNG1 LRRN3 GUCY1A1 MACF1 KCNS3 VEGFD	1.34e-05	198	116	6	e0e47cf65774191981840b22905b2094b95abe0f
ToppCell	Hematolymphoid-Microglia-TYROBP----L1-3\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	NRIP1 BMP2K CPED1 ITGB5 SFMBT2 AKAP13	1.41e-05	200	116	6	a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCell	Hematolymphoid-Microglia-TYROBP--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	NRIP1 BMP2K CPED1 ITGB5 SFMBT2 AKAP13	1.41e-05	200	116	6	dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCell	Hematolymphoid-Microglia-TYROBP-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	NRIP1 BMP2K CPED1 ITGB5 SFMBT2 AKAP13	1.41e-05	200	116	6	3bba5219453322198e8fdb0921d5f8c403598751
ToppCell	Hematolymphoid-Microglia\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	NRIP1 BMP2K CPED1 ITGB5 SFMBT2 AKAP13	1.41e-05	200	116	6	21bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCell	Hematolymphoid-Microglia-TYROBP---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	NRIP1 BMP2K CPED1 ITGB5 SFMBT2 AKAP13	1.41e-05	200	116	6	a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCell	Hematolymphoid-Microglia-TYROBP\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	NRIP1 BMP2K CPED1 ITGB5 SFMBT2 AKAP13	1.41e-05	200	116	6	33036d21c1c82109284473a515c4f890b33fdd5c
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	KIF1B CSMD2 VPS13D ASXL3 ZBTB40	2.77e-05	135	116	5	3351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCell	367C-Epithelial_cells-Epithelial-D_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RFTN1 HHIP NLRC5 PLA2G1B FGG	3.41e-05	141	116	5	f3b1d757c4cac8596c542959c8f27f8bcaf3f513
ToppCell	367C-Epithelial_cells-Epithelial-D_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RFTN1 HHIP NLRC5 PLA2G1B FGG	3.41e-05	141	116	5	bf68a54e755cda89fbc416636e522cd71d1e42d0
ToppCell	MS-CD4-CD8_2\|MS / Condition, Cell_class and T cell subcluster	ATP13A4 ZNF280D MLC1 ADGRE1 SMAD1	4.44e-05	149	116	5	08fb6be5599c5988890c851ce5ac6781c319948e
ToppCell	tumor_Lung-B_lymphocytes-GC_B_cells_in_the_LZ\|tumor_Lung / Location, Cell class and cell subclass	CFAP251 ZNF581 RFTN1 MIXL1 JCHAIN	5.53e-05	156	116	5	b5851474ba14dd2b4867415828b52dd98ecdd6d3
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	ENPP1 RNF213 JCHAIN NLRC5 MACF1	5.53e-05	156	116	5	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-plasmacytoid_dendritic_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	C12orf71 DLL4 ZNF507 NTNG1 USP40	5.70e-05	157	116	5	ffb8dd381e6b9adc5283fb49586e8bd63773c8d6
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	C12orf71 DLL4 ZNF507 NTNG1 USP40	5.70e-05	157	116	5	c488ab1d6c6c7e5c2f4426805d1366b44711a031
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D231\|Adult / Lineage, Cell type, age group and donor	DGKB CPED1 ADAMTS10 GUCY1A1 JAG1	5.87e-05	158	116	5	8d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCell	10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-LMPP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	NTNG1 GUCY1A1 MLC1 JCHAIN ZNF239	6.23e-05	160	116	5	60fa1c717410aad7e8647703cb416cd7617cac29
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	NRIP1 ENPP1 GUCY1A1 JAG1 IL23R	7.42e-05	166	116	5	773673a5d0430640439845b264740bfbbdad0cb2
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like\|GI_small-bowel / Manually curated celltypes from each tissue	NRIP1 ENPP1 GUCY1A1 JAG1 IL23R	7.63e-05	167	116	5	3ae46c6363da76c8e1f5579e6027bf88ed637a44
ToppCell	10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like\|GI_small-bowel / Manually curated celltypes from each tissue	NRIP1 ENPP1 JAG1 FGG IL23R	7.85e-05	168	116	5	d02eba7ece17edcdd47fd6b784c93910ce61090f
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-plasma_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP1 CPED1 ADORA3 LRRN3 JCHAIN	7.85e-05	168	116	5	bc7d5f0e5d222922eaf1c8e8c87aab189209d6b6
ToppCell	10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	NRIP1 ENPP1 PLXNC1 JAG1 IL23R	8.30e-05	170	116	5	97df5ffb328196c46568975d2d97722bcc753bf5
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CPED1 RFTN1 OTOGL PLXNC1 KCNS3	8.30e-05	170	116	5	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 CPED1 ADAMTS12 RFTN1 FGG	8.53e-05	171	116	5	5d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HAUS6 CPED1 HHIP LRRN3 VEGFD	8.77e-05	172	116	5	29c8510f26527d487d0fc3543102d067cdb281a6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRPS1 CPED1 GUCY1A1 PCDH19 KCNS3	9.01e-05	173	116	5	d17e50dc400098374af626803dec1241ec566769
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Pro-B/Pre-B_transition\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	RAG1 GNB1L JCHAIN NLRC5 SMAD1	9.51e-05	175	116	5	f86d2d212f8314b2410d5d84ef092b0b38607ea4
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Fst\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NTNG1 RFTN1 BMPR1B AKAP13 VEGFD	9.77e-05	176	116	5	a1b9f8f199a028b3fa85de43fe96bc29f387bfd8
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DSG2 ENPP1 BMPR1B SCUBE1 NOTUM	9.77e-05	176	116	5	77c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 RAG1 DLL4 TRIM45 BST1	9.77e-05	176	116	5	7292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATR3 CPED1 ADAMTS10 GUCY1A1 MACF1	9.77e-05	176	116	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPED1 ADAMTS10 LRRN3 BST1 C1orf159	9.77e-05	176	116	5	b4a23d8d1414434adeb237a96f28c825f1aebd77
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPED1 ADAMTS10 LRRN3 BST1 C1orf159	9.77e-05	176	116	5	66c9c6b59030f67e8d746a9c6930e50923f2ded1
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 RAG1 DLL4 TRIM45 BST1	9.77e-05	176	116	5	88ca2f83d8301633232735f39b0683efe49d0b86
ToppCell	facs-Skin-Anagen-3m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 ADORA3 RFTN1 PLXNC1 IL23R	1.00e-04	177	116	5	7853430fb0d1a18d835e8956777e0616c5d7d412
ToppCell	facs-Skin-Anagen-3m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 ADORA3 RFTN1 PLXNC1 IL23R	1.00e-04	177	116	5	395f005f019aabb18738d3a10a04c37f216deda3
ToppCell	facs-Skin-Anagen-3m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 ADORA3 RFTN1 PLXNC1 IL23R	1.00e-04	177	116	5	9a5bf67a801826d094f679dd2189b62296c9694f
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRIM45 PER3 PLXNC1 MACF1 ABCD2	1.03e-04	178	116	5	c87945146b2734141f07b39d268e0d8086ee0364
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_4\|Classical_Monocyte / Disease condition and Cell class	ARHGAP35 RFC3 RFTN1 GAR1 C1orf159	1.06e-04	179	116	5	9d51318ac198a8801bd5c7031ebf2b0c74ffeeb6
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ENPP1 DGKB ADAMTS12 GUCY1A1 JAG1	1.11e-04	181	116	5	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAUS6 STAB2 DLL4 OIT3 PLXNC1	1.11e-04	181	116	5	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	droplet-Lung-nan-21m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 HHIP NOTUM GUCY1A1 KCNS3	1.17e-04	183	116	5	b153425ab0df1e5fa9b953e1f6d4e8e3dc6621b0
ToppCell	LV-07._Pericyte\|World / Chamber and Cluster_Paper	DGKB ADAMTS12 VPS13D GUCY1A1 JAG1	1.17e-04	183	116	5	273db6a3b00a93ca852498471187b642b5368185
ToppCell	droplet-Lung-nan-21m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 HHIP NOTUM GUCY1A1 KCNS3	1.17e-04	183	116	5	19e7be1cfdd111bfb840532a6f7c780345dffccf
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ZFAND3 CPED1 HHIP NOTUM PLXNC1	1.17e-04	183	116	5	e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 STAB2 DGKB OTOGL ASXL3	1.20e-04	184	116	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like\|lymph-node_spleen / Manually curated celltypes from each tissue	NRIP1 ENPP1 GUCY1A1 KCNS3 IL23R	1.20e-04	184	116	5	d97471a4fe17cba6880ccf1a04cc00c741558124
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 STAB2 DGKB OTOGL ASXL3	1.20e-04	184	116	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A4 STAB2 DGKB OTOGL ASXL3	1.20e-04	184	116	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ENPP1 DGKB ADAMTS12 GUCY1A1 JAG1	1.20e-04	184	116	5	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBL2 F13B TIMM9 GAR1 EIF2S2	1.23e-04	185	116	5	5414a66169c39d09a67b1050aad5e61f46b3749a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CFAP251 ZNF280B ADAMTS10 BMPR1B MLC1	1.27e-04	186	116	5	facc1bd8920003ad03d1893c32fc606d82b4d50a
ToppCell	droplet-Lung-nan-18m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 HHIP NOTUM GUCY1A1 CORIN	1.27e-04	186	116	5	b58db5abdd3e9f0214b198c3cbd09b0b3c321eab
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 HHIP NOTUM GUCY1A1 CORIN	1.27e-04	186	116	5	cd6502bbf9dce318fdbb4965d49df8951e5f795c
ToppCell	facs-Heart-LA-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RDH5 DGKB GUCY1A1 PCDH19 JAG1	1.30e-04	187	116	5	a12f383b02b07af32cc53a154685df8dba8fbd3f
ToppCell	droplet-Fat-SCAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM45 BMPR1B PER3 BRCA2 FGG	1.30e-04	187	116	5	5fada3c5a58c1890029ccbfff2608b33f8cd2df7
ToppCell	droplet-Fat-SCAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM45 BMPR1B PER3 BRCA2 FGG	1.30e-04	187	116	5	766e808138fc2cd623c2e6d57fcb5c7378da0e03
ToppCell	facs-Heart-LA-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RDH5 DGKB GUCY1A1 PCDH19 JAG1	1.30e-04	187	116	5	c40c152fa14e6afc9188549534b64ccbaded56b3
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GNB1L ZBTB49 BMPR1B BST1 PUS10	1.30e-04	187	116	5	22fd1959879705a8c1128faa9de66696c4e0b7e3
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GNB1L ZBTB49 BMPR1B BST1 PUS10	1.30e-04	187	116	5	5fae538de481367cf6d9a2d52190d77b99f6922c
ToppCell	droplet-Fat-SCAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM45 BMPR1B PER3 BRCA2 FGG	1.30e-04	187	116	5	f49d06600060deeb2fc1b1da5b93496535f20104
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GNB1L ZBTB49 BMPR1B BST1 PUS10	1.30e-04	187	116	5	0526c0a818cf28fd5b6ff65fe260e3c3a4a98a2a
ToppCell	10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-ELP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	RAG1 SFMBT2 GUCY1A1 JCHAIN MACF1	1.33e-04	188	116	5	0a47de24812c619f6756c9351a413b109128d54f
ToppCell	IPF-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	RFTN1 HHIP PLA2G1B AKAP13 FGG	1.33e-04	188	116	5	5f5fad2773e421760e67dbace23fd1f847a2e1e0
ToppCell	COPD-Myeloid-DC_Mature\|COPD / Disease state, Lineage and Cell class	BMP2K DSG2 RFTN1 UBE2F UVRAG	1.33e-04	188	116	5	de93ccb53edb8599da9e312db0e3af604c21f673
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CPED1 HHIP GUCY1A1 MACF1 VEGFD	1.33e-04	188	116	5	3f0f662be684e3a4c6652e636cc135a39a1d2790
Disease	Malignant neoplasm of breast	NRIP1 ERBB2 DLL4 GNB1L TECTA HNRNPK PER3 BRCA2 OTOGL JAG1 EIF2S2 NLRC5 MACF1 HERC2 ZNF646	1.53e-05	1074	113	15	C0006142
Disease	complex trait	GAPVD1 TRPS1 ZNF507 F13B HHIP NLRC5 MACF1	8.60e-05	271	113	7	EFO_0010578
Disease	squamous cell carcinoma	TRPS1 ADAMTS12 BRCA2 HERC2	1.30e-04	67	113	4	EFO_0000707
Disease	Moyamoya disease (is_implicated_in)	RNF213 GUCY1A1	1.44e-04	5	113	2	DOID:13099 (is_implicated_in)
Disease	Bone Diseases, Developmental	PCSK5 TRPS1 BMPR1B	1.50e-04	27	113	3	C0005941
Disease	Breast Carcinoma	NRIP1 ERBB2 DLL4 HNRNPK PER3 BRCA2 JAG1 EIF2S2 HERC2	2.32e-04	538	113	9	C0678222
Disease	diverticular disease	MAPKAP1 PCSK5 TRPS1 HHIP BMPR1B NOTUM	3.04e-04	236	113	6	EFO_0009959
Disease	Bipolar Disorder	GNB1L MBL2 NTNG1 DGKB PER3 BRCA2 MLC1 PLA2G1B	5.12e-04	477	113	8	C0005586
Disease	Idiopathic pulmonary hypertension	BMPR1B SMAD1	5.14e-04	9	113	2	C0152171
Disease	Glioma	ERBB2 BRCA2	5.14e-04	9	113	2	cv:C0017638
Disease	Neoplasm of uncertain or unknown behavior of breast	ERBB2 BRCA2 HERC2	5.24e-04	41	113	3	C0496956
Disease	Breast adenocarcinoma	ERBB2 BRCA2 HERC2	5.24e-04	41	113	3	C0858252
Disease	Malignant neoplasm of salivary gland	GUCY1A1 MLC1 JAG1	6.90e-04	45	113	3	C0220636
Disease	Salivary Gland Neoplasms	GUCY1A1 MLC1 JAG1	7.84e-04	47	113	3	C0036095
Disease	HMG CoA reductase inhibitor use measurement	TRPS1 BMPR1B OIT3 BRCA2 GUCY1A1	8.21e-04	189	113	5	EFO_0009932
Disease	basal cell carcinoma	HAUS6 TRPS1 ADAMTS12 BRCA2 HERC2	8.21e-04	189	113	5	EFO_0004193
Disease	Mammary Carcinoma, Human	NRIP1 ERBB2 DLL4 HNRNPK PER3 BRCA2 JAG1 EIF2S2	9.53e-04	525	113	8	C4704874
Disease	Mammary Neoplasms, Human	NRIP1 ERBB2 DLL4 HNRNPK PER3 BRCA2 JAG1 EIF2S2	9.53e-04	525	113	8	C1257931
Disease	Mammary Neoplasms	NRIP1 ERBB2 DLL4 HNRNPK PER3 BRCA2 JAG1 EIF2S2	9.76e-04	527	113	8	C1458155
Disease	juvenile polyposis syndrome (implicated_via_orthology)	BMPR1B SMAD1	1.10e-03	13	113	2	DOID:0050787 (implicated_via_orthology)
Disease	keratinocyte carcinoma	HAUS6 TRPS1 BRCA2 HERC2	1.12e-03	118	113	4	EFO_0010176
Disease	cortical thickness	TRPS1 ARHGAP35 CPED1 ITGB5 HHIP VPS13D SCUBE1 PLXNC1 JAG1 EIF2S2 MACF1 KCNS3	1.17e-03	1113	113	12	EFO_0004840
Disease	actinic keratosis	TRPS1 HERC2	1.28e-03	14	113	2	EFO_0002496
Disease	triacylglycerol 48:4 measurement	MBL2 SFMBT2	1.28e-03	14	113	2	EFO_0010407
Disease	ovarian cancer (is_implicated_in)	ERBB2 MBL2 BRCA2	1.31e-03	56	113	3	DOID:2394 (is_implicated_in)
Disease	Idiopathic pulmonary arterial hypertension	BMPR1B SMAD1	1.68e-03	16	113	2	C3203102
Disease	Eye Abnormalities	BMPR1B JAG1	1.90e-03	17	113	2	C0015393
Disease	Moyamoya Disease	RNF213 JAG1	1.90e-03	17	113	2	C0026654
Disease	Schizophrenia	NRIP1 GNB1L NTNG1 CSMD2 ADAMTS12 ZNF530 MLC1 JAG1 PLA2G1B KCNS3	2.12e-03	883	113	10	C0036341
Disease	migraine disorder, systolic blood pressure	RNF213 ITGB5	2.14e-03	18	113	2	EFO_0006335, MONDO_0005277
Disease	colorectal cancer	TRPS1 RFC3 HHIP SCUBE1 ZBTB40 MACF1 KCNS3 HERC2	2.30e-03	604	113	8	MONDO_0005575
Disease	skin sensitivity to sun	ADAMTS12 HERC2	2.38e-03	19	113	2	EFO_0004795
Disease	osteochondrodysplasia (is_implicated_in)	TRPS1 BMPR1B	2.38e-03	19	113	2	DOID:2256 (is_implicated_in)
Disease	blood arsenic measurement	ZNF280D MBL2	2.38e-03	19	113	2	EFO_0021527
Disease	anorectal malformation	ZNF507 CSMD2	2.38e-03	19	113	2	MONDO_0019938
Disease	multiple sclerosis (is_implicated_in)	KIF1B JAG1 IL23R	2.80e-03	73	113	3	DOID:2377 (is_implicated_in)
Disease	bone density, lean body mass	CPED1 ZBTB40	2.91e-03	21	113	2	EFO_0003923, EFO_0004995
Disease	stem Cell Growth Factor beta measurement	PCSK5 STAB2 KCNS3	3.02e-03	75	113	3	EFO_0008292
Disease	Autosomal Recessive Primary Microcephaly	STIL CIT	3.19e-03	22	113	2	C3711387
Disease	Primary microcephaly	STIL CIT	3.19e-03	22	113	2	C0431350
Disease	body surface area	PCSK5 TRPS1 CPED1 ADAMTS10 TRIM66 HHIP MACF1 AKAP13	3.37e-03	643	113	8	EFO_0022196
Disease	Carcinoma of lung	ERBB2 BRCA2	3.49e-03	23	113	2	C0684249
Disease	dilated cardiomyopathy (implicated_via_orthology)	ERBB2 DLL4 JAG1	3.63e-03	80	113	3	DOID:12930 (implicated_via_orthology)
Disease	Neoplasm of the genitourinary tract	ERBB2 BRCA2	3.80e-03	24	113	2	cv:C0042065
Disease	lateral orbital frontal cortex volume measurement	KIF1B RFTN1	3.80e-03	24	113	2	EFO_0010312

Protein segments in the cluster

Peptide	Gene	Start	Entry
HTAQEPSTVCKICEL	ZNF280B	366	Q86YH2
HTPHEFSTICKICEL	ZNF280D	381	Q6N043
CTLVCPLHNQEVTAE	ERBB2	311	P04626
CPINCTHSCVDLDDK	ERBB2	626	P04626
VKLLQCVDHSTHPDC	BST1	266	Q10588
CEVHCPTNELLTDST	CSMD2	2351	Q7Z408
EIHCSDDENTPCHIK	CPED1	561	A4D0V7
ENTEILHCTETICEK	ABCD2	61	Q9UBJ2
ILKACVVCHPSDSLD	ADORA3	296	P0DMS8
HCVPCSLQEADTVLL	ATP13A4	61	Q4VNC1
ETIAPGHDCCETVKV	AKAP13	56	Q12802
LHSEKPECRISAICS	DLL4	646	Q9NR61
HCPESEKCLLSIEDE	ANKRD12	1671	Q6UB98
DTCEAVARLHQCKTP	BMP2K	161	Q9NSY1
CTERNECNKDLHPTL	BMPR1B	96	O00238
KEIETSEPCSCIHFT	CIT	1726	O14578
SICECQDENHKTIPE	ASXL3	461	Q9C0F0
PDTVDICVSGECKHV	ADAMTS10	666	Q9H324
IRSVTCAKNHDEPCD	ADAMTS12	966	P58397
LFVEPKDAICAISCH	CFAP251	601	Q8TBY9
CEHILADPVETNCKH	RAG1	296	P15918
LNLELHCDLTPKTCE	PPIL2	291	Q13356
LDCCSSLDHPTDQKL	RFTN1	126	Q14699
EDCCEESSPTVALLH	EDC4	246	Q6P2E9
PEKQVLTLTVCECLH	DSG2	581	Q14126
CLHCISVSPISEEQD	PCDH19	736	Q8TAB3
IKSQDPSVCCIQETH	nan	31	O00370
SEQKVCSRIACHEEP	GNB1L	196	Q9BYB4
HLCSICDLPVHSNKE	MATR3	291	P43243
DLELDTLPCCAETHK	HERC2	3856	O95714
LDHCIQPAVITKDVC	KIF1B	1391	O60333
LLERSKCHESTVCPD	KRT37	136	O76014
LLERSKCHESTVCPD	KRT38	136	O76015
SPAECCQHAKILEDT	GAPVD1	66	Q14C86
LDPTQEDCVATHRIC	HK2	361	P52789
SSQPTCRKEHETCLA	F13B	141	P05160
ESEPCCLTVVEKIHS	PER3	246	P56645
QDCIHEKTCKECTPE	PCSK5	1331	Q92824
KTLTLHCVCPENEGS	PLXNA3	1476	P51805
NKHKSCSECLTATDP	PLXNC1	456	O60486
SEDNHTCQVPVLCKS	OIT3	256	Q8WWZ8
FCDVHPVLKLACTET	OR4S2	176	Q8NH73
EVILAVCHPDCITTI	MACF1	2961	O94854
EDAQKTCPAVIACSS	MBL2	26	P11226
SNCVPIDLSCKHRTE	NRIP1	436	P48552
DSSELPHCLEVCRQS	METTL23	51	Q86XA0
VDQCSEDAPEKCHEL	KCNS3	421	Q9BQ31
TSCKDTSQTPLHCEN	ENPP1	836	P22413
CHTCRSPDTILQKDT	EIF2S2	281	P20042
KPDNQTCHSLCRDEV	ITGB5	651	P18084
KVVELCHCVDETQEP	NLRC5	611	Q86WI3
HTDCVDTITCAPTEA	NOTUM	276	Q6P988
ITTVLDDHTPQCNCT	OTOP1	241	Q7RTM1
SPKAVCAVLEIECAH	PUS10	271	Q3MIT2
CQEPCKDTVQIHDIT	FGG	161	P02679
EIHTVCSQKEDSLCP	BRCA2	541	P51587
DKSTLPFCQAHLCEE	DHRS4-AS1	11	Q9P1J3
CTAECPKHFQETLIC	IL23R	101	Q5VWK5
NTCSPEVIHLKDIVC	DGKB	126	Q9Y6T7
CTILVPKCDVNTGEH	CORIN	511	Q9Y5Q5
SHLTEEKVISDCECV	HAUS6	651	Q7Z4H7
DCECVPQKHVLTSHI	HAUS6	661	Q7Z4H7
HAETSTEVICPICAA	KCMF1	101	Q9P0J7
HLSDLCKKCDPTEVE	JCHAIN	86	P01591
ALTHTAQLPECCVDV	C1orf159	56	Q96HA4
TDDCHIDAICQNTPK	SCUBE1	41	Q8IWY4
TTSFQDCEAKVHCSP	SCUBE1	731	Q8IWY4
QCESPDETIKPCEAH	OTOGL	1111	Q3ZCN5
APSIEDICHVLSTVC	RFC3	186	P40938
SHLKDHCRTTPCEVI	JAG1	561	P78504
SKLTCECEHNTTGPD	NTNG1	311	Q9Y2I2
FLHPCEDDIVCKCTT	GAR1	76	Q9NY12
EFHPVSEAELCCTVE	UVRAG	616	Q9P2Y5
HTVCTTCLEQLEPFS	TRIM45	46	Q9H8W5
VAELEANLPCTCKVH	UBE2F	41	Q969M7
KEISIHSNPIRCDCV	LRRN3	361	Q9H3W5
SCLDVLICPLTHEET	RIC8B	291	Q9NVN3
TTIKLFQECCPHSTD	HNRNPK	176	P61978
RETNKEECICSHPEP	MIIP	206	Q5JXC2
LLCACDLAEEKSPSH	MAPKAP1	436	Q9BPZ7
SGTPVDELDKCCQTH	PLA2G1B	56	P04054
QTLTPESSCLREDHC	PPP1R15B	251	Q5SWA1
ICDPDLTKVSRCLEH	RDH5	256	Q92781
SCPACVDAKIEHLIS	ARHGAP35	561	Q9NRY4
LLEEIKCALCSPHSQ	HHIP	106	Q96QV1
DLQSHHELKPLECCE	SMAD1	96	Q15797
TDINECLTSSVCPEH	ADGRE1	131	Q14246
SPHCVPSKLCLDDTE	C12orf40	96	Q86WS4
PEKDDTPSHTQAQCC	C12orf71	196	A8MTZ7
TVKACLPDEHCQSTT	TEPP	111	Q6URK8
CSSDEDILCLKFHPL	SUPT6H	931	Q7KZ85
TDNRVHCETIPCKDD	TECTA	1066	O75443
TTEAISCIKEVLCDH	RNF213	2491	Q63HN8
CHQCSFTTPDVDVLL	TRPS1	616	Q9UHF7
DFLIPCKVHTQELCS	STIL	121	Q15468
EKTCPLCRTVISDHI	RNFT1	406	Q5M7Z0
CDTITEKGTVPHSCE	TMEM179	136	Q6ZVK1
EIILNHCAPGTETKC	MIXL1	156	Q9H2W2
KPETDTCSSLAVCDH	STYXL2	906	Q5VZP5
SENCPENCSIHTKTK	SFMBT2	646	Q5VUG0
TPAADKTAAHICSIC	ZNF646	566	O15015
VKPEETTCSEHCLQK	TIMM9	41	Q9Y5J7
CEPITSCLEQTGKCH	STAB2	951	Q8WWQ8
NVDSTAESCPKCEHP	POLR3K	61	Q9Y2Y1
SCEKLLDEHVLTCTN	ZBTB1	226	Q9Y2K1
CPICEHIADNSKDLE	ZNF507	671	Q8TCN5
ECSTLCATPEEFLEH	ZNF526	201	Q8TF50
TVESQPCAVSHSECI	ZBTB49	251	Q6ZSB9
STDKSHPCEICTPVL	ZNF530	86	Q6P9A1
HTPHEFSTICKICEL	ZNF280C	376	Q8ND82
SITHSEVKPFECDIC	ZNF581	106	Q9P0T4
SCSQQRAHTEEKPCD	ZNF239	166	Q16600
EEDRCSHSKKLCPID	VEGFD	211	O43915
GKTCFVDCLIEQTHP	EFTUD2	141	Q15029
EPFHITCKITNCSER	TRAPPC13	321	A5PLN9
PLHTQEVLKLFCETC	TRIM66	66	O15016
SSDGEKCCQVIESPH	USP40	651	Q9NVE5
KEECGPCTDTAHVSL	ZFAND3	96	Q9H8U3
EHFKQSETTFPCELC	ZBTB40	1126	Q9NUA8
QESSSPEDHVCLLDC	VPS13D	2141	Q5THJ4
SSESCKATVPICQDI	GUCY1A1	36	Q02108
SHVAAECPSKCLVEV	MLC1	246	Q15049