Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	pyrimidine nucleotide transmembrane transporter activity	SLC25A36 SLC25A33	1.83e-05	2	86	2	GO:0015218
GeneOntologyBiologicalProcess	pyrimidine nucleotide import into mitochondrion	SLC25A36 SLC25A33	1.68e-05	2	85	2	GO:1990519
GeneOntologyBiologicalProcess	pyrimidine nucleotide transport	SLC25A36 SLC25A33	1.68e-05	2	85	2	GO:0006864
GeneOntologyCellularComponent	main axon	ANK3 KCNC3 DLG2 CDH1 GABBR1	3.91e-05	89	89	5	GO:0044304
GeneOntologyCellularComponent	axon	DIP2B GABRR2 NEFL ANK3 KCNC3 NECTIN1 SH2D3C INSRR DLG2 CDH1 GABBR1 HTT	3.87e-04	891	89	12	GO:0030424
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex, class I	PIK3R6 PIK3R2	6.33e-04	9	89	2	GO:0097651
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex, class IA	PIK3R6 PIK3R2	6.33e-04	9	89	2	GO:0005943
GeneOntologyCellularComponent	dendrite	DIP2B SNX14 ANK3 KCNC3 NECTIN1 KIRREL1 DLG2 EPHA10 GABBR1 HTT SHISA8	1.03e-03	858	89	11	GO:0030425
GeneOntologyCellularComponent	dendritic tree	DIP2B SNX14 ANK3 KCNC3 NECTIN1 KIRREL1 DLG2 EPHA10 GABBR1 HTT SHISA8	1.05e-03	860	89	11	GO:0097447
Domain	DEAD_ATP_HELICASE	DDX52 DDX3Y DDX4	3.99e-04	31	87	3	PS00039
Domain	Q_MOTIF	DDX52 DDX3Y DDX4	6.76e-04	37	87	3	PS51195
Domain	RNA_helicase_DEAD_Q_motif	DDX52 DDX3Y DDX4	6.76e-04	37	87	3	IPR014014
Domain	Helicase_C	DDX52 DDX3Y CHD7 DDX4	1.57e-03	107	87	4	PF00271
Domain	HELICc	DDX52 DDX3Y CHD7 DDX4	1.57e-03	107	87	4	SM00490
Domain	Helicase_C	DDX52 DDX3Y CHD7 DDX4	1.63e-03	108	87	4	IPR001650
Domain	HELICASE_CTER	DDX52 DDX3Y CHD7 DDX4	1.68e-03	109	87	4	PS51194
Domain	HELICASE_ATP_BIND_1	DDX52 DDX3Y CHD7 DDX4	1.68e-03	109	87	4	PS51192
Domain	DEXDc	DDX52 DDX3Y CHD7 DDX4	1.68e-03	109	87	4	SM00487
Domain	Helicase_ATP-bd	DDX52 DDX3Y CHD7 DDX4	1.74e-03	110	87	4	IPR014001
Domain	CA	FREM2 FAT2 PCDHA5 CDH1	2.05e-03	115	87	4	SM00112
Domain	Cadherin	FREM2 FAT2 PCDHA5 CDH1	2.25e-03	118	87	4	IPR002126
Domain	SAM_1	CNKSR3 SAMD5 EPHA10	3.93e-03	68	87	3	PF00536
Domain	DEAD/DEAH_box_helicase_dom	DDX52 DDX3Y DDX4	4.80e-03	73	87	3	IPR011545
Domain	DEAD	DDX52 DDX3Y DDX4	4.80e-03	73	87	3	PF00270
Pubmed	Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.	NEFL NCOR1 CHD7 BCOR SPEN HNRNPH3	4.90e-08	78	88	6	28611094
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RALGAPA1 USP31 NEFL NCOR1 PPP2CB ANK3 P3H1 MIB1 SEC16A PUS1 KIRREL1 MARVELD2 CCDC77 BCOR	3.82e-07	1049	88	14	27880917
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	GPRASP1 DIP2B NEFL NCOR1 PPP2CB AMPD2 ANK3 CNKSR3 SEC16A DLG2 CHD7 BCOR CIT	9.15e-07	963	88	13	28671696
Pubmed	Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epithelium.	MMP7 CDH1	6.33e-06	2	88	2	12759241
Pubmed	Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance.	ANK3 CDH1	6.33e-06	2	88	2	37891324
Pubmed	A conserved structural motif reveals the essential transcriptional repression function of Spen proteins and their role in developmental signaling.	NCOR1 SPEN	6.33e-06	2	88	2	12897056
Pubmed	Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington's disease.	NEFL HTT	6.33e-06	2	88	2	30209243
Pubmed	Identification of the mitochondrial pyruvate carrier in Saccharomyces cerevisiae.	SLC25A36 SLC25A33	6.33e-06	2	88	2	12887330
Pubmed	The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation.	MARVELD2 HTT	6.33e-06	2	88	2	19915590
Pubmed	Association of extracellular cleavage of E-cadherin mediated by MMP-7 with HGF-induced in vitro invasion in human stomach cancer cells.	MMP7 CDH1	6.33e-06	2	88	2	17396032
Pubmed	Cadherin controls nectin recruitment into adherens junctions by remodeling the actin cytoskeleton.	NECTIN1 CDH1	6.33e-06	2	88	2	25395582
Pubmed	The human SLC25A33 and SLC25A36 genes of solute carrier family 25 encode two mitochondrial pyrimidine nucleotide transporters.	SLC25A36 SLC25A33	6.33e-06	2	88	2	25320081
Pubmed	Association between the gamma-aminobutyric acid type B receptor 1 and 2 gene polymorphisms and mesial temporal lobe epilepsy in a Han Chinese population.	GABRR2 GABBR1	6.33e-06	2	88	2	18653317
Pubmed	[Protein kinase D3 is involved in negative regulation of MMP-7 in prostate cancer cells].	PRKD3 MMP7	6.33e-06	2	88	2	20813660
Pubmed	SUMO-Targeted Ubiquitin Ligases (STUbLs) Reduce the Toxicity and Abnormal Transcriptional Activity Associated With a Mutant, Aggregation-Prone Fragment of Huntingtin.	RNF4 HTT	6.33e-06	2	88	2	30279700
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	NCOR1 GAPVD1 DIS3L CNKSR3 ZNF185 MIB1 PUS1 MLXIP PPIP5K2 CCDC77 HNRNPH3	1.04e-05	853	88	11	28718761
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	AMPD2 GAPVD1 ANK3 DDX52 SEC16A PHTF2 DDX3Y CHD7 CCDC77 BCOR CDH1 ZMAT1	1.84e-05	1084	88	12	11544199
Pubmed	Ankyrin-G is a molecular partner of E-cadherin in epithelial cells and early embryos.	ANK3 CDH1	1.90e-05	3	88	2	17620337
Pubmed	Diverse species-specific phenotypic consequences of loss of function sorting nexin 14 mutations.	SNX14 CDH1	1.90e-05	3	88	2	32792680
Pubmed	Circadian control of fatty acid elongation by SIRT1 protein-mediated deacetylation of acetyl-coenzyme A synthetase 1.	ACSS1 CLOCK	1.90e-05	3	88	2	24425865
Pubmed	Mutant huntingtin increases nuclear corepressor function and enhances ligand-dependent nuclear hormone receptor activation.	NCOR1 HTT	1.90e-05	3	88	2	12799135
Pubmed	E-cadherin and metalloproteinase-1 and -7 polymorphisms in colorectal cancer.	MMP7 CDH1	1.90e-05	3	88	2	19634113
Pubmed	Syndecan-2 enhances E-cadherin shedding and fibroblast-like morphological changes by inducing MMP-7 expression in colon cancer cells.	MMP7 CDH1	1.90e-05	3	88	2	27270030
Pubmed	Separation force measurements reveal different types of modulation of E-cadherin-based adhesion by nectin-1 and -3.	NECTIN1 CDH1	1.90e-05	3	88	2	15550395
Pubmed	E-cadherin, beta-catenin adhesion complex and relation to matrilysin expression in pT3 rectosigmoid cancers.	MMP7 CDH1	1.90e-05	3	88	2	18674869
Pubmed	Association of E-cadherin, matrix metalloproteinases, and tissue inhibitors of metalloproteinases with the progression and metastasis of hepatocellular carcinoma.	MMP7 CDH1	1.90e-05	3	88	2	16474379
Pubmed	The E3 ubiquitin ligase MIB1 suppresses breast cancer cell migration through regulating CTNND1 protein level.	MIB1 CDH1	1.90e-05	3	88	2	37209565
Pubmed	Decreased GABA(B) receptors in the cingulate cortex and fusiform gyrus in autism.	GABRR2 GABBR1	1.90e-05	3	88	2	20557420
Pubmed	Aberrant expression of Pax-2 in Danforth's short tail (Sd) mice.	NEFL CDH1	1.90e-05	3	88	2	8482415
Pubmed	Regulation of E-cadherin endocytosis by nectin through afadin, Rap1, and p120ctn.	NECTIN1 CDH1	1.90e-05	3	88	2	15857834
Pubmed	Mesothelial cells interact with tumor cells for the formation of ovarian cancer multicellular spheroids in peritoneal effusions.	MUC16 CDH1	1.90e-05	3	88	2	27612856
Pubmed	Matrilysin (Matrix Metalloproteinase-7) regulates anti-inflammatory and antifibrotic pulmonary dendritic cells that express CD103 (alpha(E)beta(7)-integrin).	MMP7 CDH1	1.90e-05	3	88	2	19893044
Pubmed	BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.	NCOR1 SEC16A BCOR	3.05e-05	24	88	3	33722704
Pubmed	Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin.	NCOR1 HTT	3.79e-05	4	88	2	10441327
Pubmed	Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of β-catenin.	ANK3 CDH1	3.79e-05	4	88	2	24821222
Pubmed	Transcriptional activity of Sp1 is regulated by molecular interactions between the zinc finger DNA binding domain and the inhibitory domain with corepressors, and this interaction is modulated by MEK.	NCOR1 BCOR	3.79e-05	4	88	2	15878880
Pubmed	Distinction of hepatocellular adenoma from hepatocellular carcinoma with and without cirrhosis using E-cadherin and matrix metalloproteinase immunohistochemistry.	MMP7 CDH1	3.79e-05	4	88	2	19465902
Pubmed	Phosphorylated hepatocyte growth factor receptor/c-Met is associated with tumor growth and prognosis in patients with bladder cancer: correlation with matrix metalloproteinase-2 and -7 and E-cadherin.	MMP7 CDH1	3.79e-05	4	88	2	19121849
Pubmed	E-cadherin polarity is determined by a multifunction motif mediating lateral membrane retention through ankyrin-G and apical-lateral transcytosis through clathrin.	ANK3 CDH1	3.79e-05	4	88	2	23530049
Pubmed	TOPAZ1, a novel germ cell-specific expressed gene conserved during evolution across vertebrates.	TOPAZ1 DDX4	3.79e-05	4	88	2	22069478
Pubmed	Glycogen synthase kinase 3β suppresses polyglutamine aggregation by inhibiting Vaccinia-related kinase 2 activity.	MARVELD2 HTT	3.79e-05	4	88	2	27377031
Pubmed	JNK signaling regulates E-cadherin junctions in germline cysts and determines primordial follicle formation in mice.	CDH1 DDX4	3.79e-05	4	88	2	27013242
Pubmed	Scaffold attachment factor SAFB1 suppresses estrogen receptor alpha-mediated transcription in part via interaction with nuclear receptor corepressor.	NCOR1 SAFB	3.79e-05	4	88	2	16195251
Pubmed	BAX-mediated cell death affects early germ cell loss and incidence of testicular teratomas in Dnd1(Ter/Ter) mice.	CDH1 DDX4	3.79e-05	4	88	2	19389346
Pubmed	PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.	PPP2CB GAPVD1 SAFB PIK3R2 MIB1 SEC16A	4.02e-05	247	88	6	32989298
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	DIP2B NEFL PPP2CB ANK3 DLG2 CIT	4.40e-05	251	88	6	27507650
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NCOR1 CHD7 BCOR SPEN	6.04e-05	83	88	4	28794006
Pubmed	Co-repressor activity of scaffold attachment factor B1 requires sumoylation.	NCOR1 SAFB	6.30e-05	5	88	2	21527249
Pubmed	Circadian proteins CLOCK and BMAL1 in the chromatoid body, a RNA processing granule of male germ cells.	CLOCK DDX4	6.30e-05	5	88	2	22900038
Pubmed	HIV-associated disruption of tight and adherens junctions of oral epithelial cells facilitates HSV-1 infection and spread.	NECTIN1 CDH1	6.30e-05	5	88	2	24586397
Pubmed	Novel domains of expression for orphan receptor tyrosine kinase Ror2 in the human and mouse reproductive system.	CDH1 DDX4	6.30e-05	5	88	2	24753105
Pubmed	Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase.	MRPS30 NLN	6.30e-05	5	88	2	16497723
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	SOX6 NCOR1 SEC16A CHD7 SPEN CLOCK	8.37e-05	282	88	6	23667531
Pubmed	Distinct role of protein phosphatase 2A subunit Calpha in the regulation of E-cadherin and beta-catenin during development.	PPP2CB CDH1	9.43e-05	6	88	2	10781942
Pubmed	The cell adhesion gene PVRL3 is associated with congenital ocular defects.	NECTIN1 CDH1	9.43e-05	6	88	2	21769484
Pubmed	KR-POK interacts with p53 and represses its ability to activate transcription of p21WAF1/CDKN1A.	NCOR1 BCOR	9.43e-05	6	88	2	22253232
Pubmed	EpCAM is essential for maintenance of the small intestinal epithelium architecture via regulation of the expression and localization of proteins that compose adherens junctions.	NECTIN1 CDH1	9.43e-05	6	88	2	33416101
Pubmed	Characterization and significance of adhesion and junction-related proteins in mouse ovarian follicles.	NECTIN1 CDH1	9.43e-05	6	88	2	22321830
Pubmed	Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo.	NECTIN1 CDH1	9.43e-05	6	88	2	15108322
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	USP31 TOPAZ1 P3H1 INSRR SEC16A MUC16 SPEN	9.76e-05	420	88	7	28065597
Pubmed	A cellular system that degrades misfolded proteins and protects against neurodegeneration.	RNF4 HTT	1.32e-04	7	88	2	24882209
Pubmed	Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.	ANK3 CDH1	1.32e-04	7	88	2	7495297
Pubmed	The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling.	NCOR1 SPEN	1.32e-04	7	88	2	11867749
Pubmed	CHD1 associates with NCoR and histone deacetylase as well as with RNA splicing proteins.	NCOR1 SAFB	1.32e-04	7	88	2	12890497
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	RALGAPA1 PPP2CB SEC16A DDX3Y CHD7	1.48e-04	197	88	5	20811636
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	NCOR1 GAPVD1 ANK3 SEC16A MUC16 KIRREL1 MARVELD2 SPEN ZMAT1	1.57e-04	777	88	9	35844135
Pubmed	A novel POK family transcription factor, ZBTB5, represses transcription of p21CIP1 gene.	NCOR1 BCOR	1.75e-04	8	88	2	19491398
Pubmed	AnkG hemizygous mice present cognitive impairment and elevated anxiety/depressive-like traits associated with decreased expression of GABA receptors and postsynaptic density protein.	ANK3 GABBR1	1.75e-04	8	88	2	28821923
Pubmed	Essential role of citron kinase in cytokinesis of spermatogenic precursors.	CIT DDX4	1.75e-04	8	88	2	12432070
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TBC1D32 NCOR1 MIB1 MUC16 FGD5 CHD7 BCOR SPEN	2.18e-04	638	88	8	31182584
Pubmed	p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis.	NECTIN1 CDH1	2.25e-04	9	88	2	25387952
Pubmed	Expression of catenins during mouse embryonic development and in adult tissues.	NEFL CDH1	2.25e-04	9	88	2	8821035
Pubmed	Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling.	CDH1 DDX4	2.25e-04	9	88	2	24784881
Pubmed	NANOS2 acts as an intrinsic regulator of gonocytes-to-spermatogonia transition in the murine testes.	CDH1 DDX4	2.25e-04	9	88	2	29339164
Pubmed	Ank3 (epithelial ankyrin), a widely distributed new member of the ankyrin gene family and the major ankyrin in kidney, is expressed in alternatively spliced forms, including forms that lack the repeat domain.	ANK3 TFAP2B	2.25e-04	9	88	2	7615634
Pubmed	Generation of a biotinylatable Sox2 mouse model to identify Sox2 complexes in vivo.	SAFB ANK3	2.25e-04	9	88	2	29383478
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RALGAPA1 USP31 NEFL PPP2CB SAFB ANK3 ZNF185 SEC16A DLG2 DDX3Y CIT NDUFS8	2.57e-04	1431	88	12	37142655
Pubmed	Interaction network of human early embryonic transcription factors.	NCOR1 SEC16A CHD7 BCOR SPEN CDH1	2.74e-04	351	88	6	38297188
Pubmed	BCoR, a novel corepressor involved in BCL-6 repression.	NCOR1 BCOR	2.81e-04	10	88	2	10898795
Pubmed	GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.	SOX6 MBOAT1	2.81e-04	10	88	2	25199915
Pubmed	Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing.	GABRR2 GABBR1	2.81e-04	10	88	2	30902970
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	PRKD3 NCOR1 AMPD2 SAFB SEC16A PUS1 SPEN	2.94e-04	503	88	7	16964243
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	PRKD3 RALGAPA1 SNX14 PIK3R2 SEC16A POMGNT1 MARVELD2	2.97e-04	504	88	7	34432599
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RALGAPA1 USP31 DIP2B AMPD2 GAPVD1 CNKSR3 SEC16A MLXIP PPIP5K2	3.34e-04	861	88	9	36931259
Pubmed	Loss-of-function mutations in FREM2 disrupt eye morphogenesis.	FREM2 CDH1	3.43e-04	11	88	2	30802441
Pubmed	Sharp, an inducible cofactor that integrates nuclear receptor repression and activation.	NCOR1 SPEN	3.43e-04	11	88	2	11331609
Pubmed	Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth.	NECTIN1 CDH1	3.43e-04	11	88	2	21038445
Pubmed	The proto-oncoprotein FBI-1 interacts with MBD3 to recruit the Mi-2/NuRD-HDAC complex and BCoR and to silence p21WAF/CDKN1A by DNA methylation.	NCOR1 BCOR	3.43e-04	11	88	2	23658227
Pubmed	Somatic FGFR2 is Required for Germ Cell Maintenance in the Mouse Ovary.	CDH1 DDX4	3.43e-04	11	88	2	36786658
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	TBC1D32 FICD PPIP5K2 BCOR CDH1 NDUFS8	3.67e-04	371	88	6	15747579
Pubmed	The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.	PIK3R2 SH2D3C CDH1 GABBR1	3.82e-04	134	88	4	24658140
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	MRPS30 DIP2B NEFL ACSS1 MIB1 SEC16A PUS1 CCDC77 DDX4 HNRNPH3 NDUFS8 SHISA8	3.83e-04	1496	88	12	32877691
Pubmed	miRNAs control tracheal chondrocyte differentiation.	SOX6 SPEN	4.11e-04	12	88	2	21945074
Pubmed	DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary.	CDH1 DDX4	4.11e-04	12	88	2	21621532
Pubmed	Centrosome linker protein C-Nap1 maintains stem cells in mouse testes.	CDH1 DDX4	4.11e-04	12	88	2	35599622
Pubmed	Synergistic action of nectins and cadherins generates the mosaic cellular pattern of the olfactory epithelium.	NECTIN1 CDH1	4.11e-04	12	88	2	26929452
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	NCOR1 SAFB DDX52 CHD7 MLXIP BCOR SPEN CLOCK CDCA7L HNRNPH3 NDUFS8	4.21e-04	1294	88	11	30804502
Pubmed	The transcription factors AP-2β and AP-2α are required for survival of sympathetic progenitors and differentiated sympathetic neurons.	NEFL TFAP2B	4.85e-04	13	88	2	21539825
Pubmed	hnRNPU is required for spermatogonial stem cell pool establishment in mice.	CDH1 DDX4	4.85e-04	13	88	2	38625792
Pubmed	Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling.	CDH1 DDX4	4.85e-04	13	88	2	28341395
Interaction	DDX4 interactions	MIB1 CIT DDX4 HTT	5.27e-06	27	87	4	int:DDX4
GeneFamily	DEAD-box helicases	DDX52 DDX3Y DDX4	4.61e-04	42	65	3	499
Coexpression	BILD_E2F3_ONCOGENIC_SIGNATURE	NEFL MBOAT1 DIS3L PHTF2 CHD7 BCOR SHISA8	2.06e-05	248	88	7	M13061
Coexpression	GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN	MIB1 CHD7 MMP7 SPEN HTT SHISA8	5.58e-05	198	88	6	M6128
Coexpression	GSE3691_IFN_PRODUCING_KILLER_DC_VS_CONVENTIONAL_DC_SPLEEN_UP	FAM78A GPRASP1 DIP2B GAPVD1 DDX4 HTT	5.90e-05	200	88	6	M6363
Coexpression	GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_DN	DIS3L CNKSR3 DLG2 DDX3Y PPIP5K2 ZMAT1	5.90e-05	200	88	6	M5096
Coexpression	GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_DN	PRKD3 RALGAPA1 GPRASP1 GAPVD1 POMGNT1 CHD7	5.90e-05	200	88	6	M8040
Coexpression	GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_UP	PRKD3 NLN MBOAT1 DDX3Y CHD7 STN1	5.90e-05	200	88	6	M8489
CoexpressionAtlas	kidney_e10.5_UretericTrunk_HoxB7_top-relative-expression-ranked_100	FREM2 CHD7 MARVELD2 CDH1 TFAP2B	2.18e-05	81	88	5	gudmap_kidney_e10.5_UretericTrunk_HoxB7_100
CoexpressionAtlas	kidney_e10.5_UretericTip_HoxB7_top-relative-expression-ranked_200	FREM2 MBOAT1 CHD7 MARVELD2 CDH1 TFAP2B	3.13e-05	145	88	6	gudmap_kidney_e10.5_UretericTip_HoxB7_200
CoexpressionAtlas	kidney_e10.5_UretericTrunk_HoxB7_top-relative-expression-ranked_200	FREM2 MBOAT1 CHD7 MARVELD2 CDH1 TFAP2B	3.93e-05	151	88	6	gudmap_kidney_e10.5_UretericTrunk_HoxB7_200
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX6 FREM2 ANK3 SAMD5 DLG2 CDH1	1.84e-06	181	90	6	aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	SOX6 FREM2 ANK3 SAMD5 KIRREL1 DLG2	2.36e-06	189	90	6	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	DIP2B NEFL FAT2 ZNF185 HSF5	1.63e-05	156	90	5	ffb9249a115ce31f50b99a7a3d40bf48b9d7f2b0
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	GPRASP1 NCOR1 DCPS SH2D3C CDCA7L	2.39e-05	169	90	5	b66ffc2b2b6bfcc3a6e639d9d31d3de95f4a94e1
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	RALGAPA1 DIS3L ACOT11 MLXIP PNPO	2.83e-05	175	90	5	78a86cac3e6c0d115c997d1c29ee0e24af54551f
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SNED1 ZNF185 INSRR CDH1 TFAP2B	3.07e-05	178	90	5	cda7695411655bd6d0ba69e5041ca7530a9dad3a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FREM2 SLC25A36 ANK3 DDX3Y CIT	3.15e-05	179	90	5	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SNED1 TMPRSS9 PXDNL SAMD5 DLG2	3.24e-05	180	90	5	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SNED1 TMPRSS9 PXDNL SAMD5 DLG2	3.24e-05	180	90	5	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ACOT11 PXDNL SLC25A33 ACSS1 TFAP2B	3.50e-05	183	90	5	31ab55d5f3639f5964541d5eae23044dbda3356e
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SNED1 FAT2 ZNF185 CDH1 TFAP2B	3.59e-05	184	90	5	235890e8b424f4386b6ea52d173d20a00898df73
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX6 FREM2 ANK3 MMP7 CDH1	3.69e-05	185	90	5	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ACOT11 PXDNL SLC25A33 ACSS1 TFAP2B	3.69e-05	185	90	5	898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell	Control-Epithelial-ATII\|World / Disease state, Lineage and Cell class	FREM2 ANK3 CNKSR3 DLG2 CDH1	3.78e-05	186	90	5	f4b6e401e19a71beddc73d8a1e08359f7c4025cf
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	FREM2 ANK3 CNKSR3 DLG2 CDH1	3.98e-05	188	90	5	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MBOAT1 ANK3 KCNC3 DLG2 CDH1	4.08e-05	189	90	5	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MBOAT1 ANK3 PHTF2 DLG2 CDH1	4.08e-05	189	90	5	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	Control-Epithelial-ATII\|Control / Disease state, Lineage and Cell class	FREM2 ANK3 CNKSR3 DLG2 CDH1	4.19e-05	190	90	5	d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCell	wk_08-11-Epithelial-PNS-Schwann_precursor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NEFL TMPRSS9 DLG2 CHD7 TFAP2B	4.19e-05	190	90	5	4a777d8aa19cadd3b61b023772df142421a89113
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACOT11 PXDNL SLC25A33 ACSS1 TFAP2B	4.19e-05	190	90	5	cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	SOX6 ANK3 ACOT11 PXDNL DLG2	4.29e-05	191	90	5	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	T_cells-Central_memory_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	NEFL ANK3 CHD7 MLXIP GABBR1	4.29e-05	191	90	5	25dd538d6a361bd3367c8a1c0dfc9e7003061af3
ToppCell	Control-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	FREM2 ANK3 CNKSR3 DLG2 CDH1	4.40e-05	192	90	5	1bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MBOAT1 ANK3 DLG2 MMP7 CDH1	4.40e-05	192	90	5	0bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	USP31 FAT2 ANK3 NECTIN1 CDH1	4.40e-05	192	90	5	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SOX6 DIP2B ANK3 SAMD5 DLG2	4.40e-05	192	90	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	RALGAPA1 DIP2B MARVELD2 BCOR CLOCK	4.51e-05	193	90	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT2 MBOAT1 ANK3 NECTIN1 CDH1	4.51e-05	193	90	5	a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX6 FREM2 ANK3 ACOT11 CDH1	4.62e-05	194	90	5	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX6 FREM2 ANK3 ACOT11 SAMD5	4.62e-05	194	90	5	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FREM2 ANK3 DLG2 CDH1 CIT	4.62e-05	194	90	5	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP ANK3 ACOT11 PXDNL DLG2	4.74e-05	195	90	5	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NECTIN1 ZNF185 MUC16 BCOR CIT	4.85e-05	196	90	5	547901c7a665770eff78eede69b8625b416c8186
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX6 FREM2 ANK3 ACOT11 CDH1	4.85e-05	196	90	5	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX6 FREM2 ANK3 ACOT11 CDH1	4.85e-05	196	90	5	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NECTIN1 ZNF185 MUC16 BCOR CIT	4.85e-05	196	90	5	6e08d7ba67da161c2dca1a17c440ffb9d9b5bc3b
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ANK3 CHD7 MMP7 CDH1 ZMAT1	4.97e-05	197	90	5	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SLC25A36 GAPVD1 ANK3 MUC16 CDH1	5.34e-05	200	90	5	64462a18afca3c1a8548a857924b8166058bf958
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FAT2 ANK3 ACOT11 MUC16 CDH1	5.34e-05	200	90	5	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT2 TOPAZ1 MUC16 CDCA7L	1.49e-04	132	90	4	694b79dc31b8d7ef3c01962916d25980b76da33e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT2 TOPAZ1 MUC16 CDCA7L	1.49e-04	132	90	4	36bb06f9e97a8abbea4d06beff9e38641a5f0ff2
ToppCell	Cerebellum\|World / BrainAtlas - Mouse McCarroll V32	FAT2 CDH1 TFAP2B NDUFS8	2.25e-04	147	90	4	dd730224e39571ca2c35042e242a908a02ee377d
ToppCell	droplet-Heart-4Chambers-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POMGNT1 DDX3Y MMP7 CDH1	2.37e-04	149	90	4	38890ddde0979977c8350f01497f1245ab51641a
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb\|Cerebellum / BrainAtlas - Mouse McCarroll V32	INSRR KIRREL1 CDH1 TFAP2B	2.37e-04	149	90	4	6e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FAT2 ZNF185 INSRR CDH1	2.62e-04	153	90	4	151c469b26f9adf04dd6f117f03bef760cc3d45d
ToppCell	Ionocyte\|World / shred by cell class for nasal brushing	TMPRSS9 SAMD5 DDX4 HSF5	2.68e-04	154	90	4	6b78fb0c96fc7b5e901c39b3424f4aa8d0a6b9cf
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-Tfh\|Liver / Manually curated celltypes from each tissue	SNED1 NEFL ANK3 TMEM168	2.82e-04	156	90	4	85bc34ff507f9a66c6e3ba7a3ffd5416d0073ccf
ToppCell	facs-Marrow-KLS-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NECTIN1 MARVELD2 CLOCK HSF5	2.89e-04	157	90	4	5d08ff0ba9d3df9cc30f13cab2d2b395ea6f3446
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|343B / Donor, Lineage, Cell class and subclass (all cells)	PRKD3 RALGAPA1 DIS3L ACOT11	2.89e-04	157	90	4	0362c04b7b0b5017964b3a73ee678ae53e7238d7
ToppCell	facs-Marrow-KLS-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NECTIN1 MARVELD2 CLOCK HSF5	2.89e-04	157	90	4	ad9c9b7dfeee3ae46e7e593c51a0407df12195b4
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FREM2 ANK3 CDH1 CIT	3.03e-04	159	90	4	e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-LTi-like_NCR+_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NECTIN1 NCR2 CLOCK STN1	3.18e-04	161	90	4	d59713ca84aa2acadfc9b3150d5f525e1b288860
ToppCell	Influenza_Severe-B_memory\|World / Disease group and Cell class	MUC16 CHD7 CDCA7L SHISA8	3.25e-04	162	90	4	21eb96cd4fecd85dd6acbbc3760944fa1a7cff42
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NEFL ACSS1 EXTL1 TFAP2B	3.33e-04	163	90	4	cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ANK3 SAMD5 KIRREL1 DLG2	3.41e-04	164	90	4	b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ANK3 SAMD5 KIRREL1 DLG2	3.41e-04	164	90	4	3aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEFL DLG2 CIT EPHA10	3.49e-04	165	90	4	6d8b5669eee9b0903c9260fea707d186c9d7fefa
ToppCell	Influenza_Severe-B_memory\|Influenza_Severe / Disease group and Cell class	MUC16 CHD7 CDCA7L SHISA8	3.49e-04	165	90	4	51172acaeb667b34b8b8c7878d67cfa0c4a2dffc
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEFL DLG2 CIT EPHA10	3.49e-04	165	90	4	02cd87dfa2ca40e13455a4b9308477e82f76289b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KCNC3 PIK3R2 FGD5 BCOR	3.57e-04	166	90	4	c8fd241088de27c6e741a5dfee3cd770183b6bcb
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FREM2 NRG2 MUC16 EXTL1	3.65e-04	167	90	4	7abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FREM2 NRG2 MUC16 EXTL1	3.65e-04	167	90	4	d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCell	COVID-19_Mild-PLT_2\|World / Disease Group and Platelet Clusters	TBC1D32 GPRASP1 TOPAZ1 CHD7	3.82e-04	169	90	4	6abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANK3 ZNF185 DLG2 CDH1	3.82e-04	169	90	4	d382a76d85875663502cc7dde2e3e0682605768e
ToppCell	droplet-Lung-nan-3m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBOAT1 CDH1 CIT GABBR1	3.82e-04	169	90	4	da607c1d068038d5a3d1117f6aa6e4c6f3552e97
ToppCell	droplet-Lung-nan-3m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBOAT1 CDH1 CIT GABBR1	3.82e-04	169	90	4	a14b46231e079a0fd9f3ca13d5d48113be76fd0f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT2 KCNC3 DLG2 CDH1	3.90e-04	170	90	4	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9\|TCGA-Bladder / Sample_Type by Project: Shred V9	FAT2 ANK3 NECTIN1 SPEN	3.99e-04	171	90	4	adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIRREL1 FGD5 CHD7 SHISA8	3.99e-04	171	90	4	a5634b76476b8b2488a706bbab5141f7bd94631f
ToppCell	severe_influenza-B_memory\|World / disease group, cell group and cell class (v2)	MUC16 CHD7 CDCA7L SHISA8	4.08e-04	172	90	4	0ff38f9431cec73250c580a6010cb7891a3fe3f1
ToppCell	normal_Lung-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	NLN KCNC3 ACOT11 GABBR1	4.26e-04	174	90	4	e324320b52c904496e26fcecfa179b3431729ec0
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT2 NECTIN1 ZNF185 MUC16	4.26e-04	174	90	4	207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACOT11 PXDNL ACSS1 TFAP2B	4.35e-04	175	90	4	e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIRREL1 FGD5 CHD7 SHISA8	4.35e-04	175	90	4	e78bf0c33a741bb97e987e41ac33da9e623a08ec
ToppCell	P28-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ANK3 KCNC3 ACSS1 CDH1	4.35e-04	175	90	4	8a4ed775ff973123dbcfe9c809959d11a62450c9
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	KCNC3 SLC25A33 DDX3Y CDH1	4.35e-04	175	90	4	c58a1f02d1e559d3638fe1500e960e82a8a7187b
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBOAT1 MARVELD2 CDH1 TFAP2B	4.45e-04	176	90	4	8e4600efeea095a92178cfd26d7c58db7dfc0c80
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	TMEM168 CHD7 HSF5 HTT	4.45e-04	176	90	4	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PXDNL DLG2 DDX3Y MMP7	4.54e-04	177	90	4	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	TMEM168 CHD7 HSF5 HTT	4.54e-04	177	90	4	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-NK_T_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIK3R6 EXTL1 DDX4 STN1	4.54e-04	177	90	4	89e9ac601bc80bd33141da84056189950e563a1e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MBOAT1 ANK3 SAMD5 CDH1	4.54e-04	177	90	4	f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SOX6 FREM2 MUC16 EXTL1	4.64e-04	178	90	4	1e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIK3R2 MMP7 CDH1 EPHA10	4.64e-04	178	90	4	f3b5eeca6081d65d48824b5d13e3b8eb5fdeb2dd
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIRREL1 FGD5 CHD7 SHISA8	4.74e-04	179	90	4	01302505816f272243659e20d751b61a198a2fc0
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX6 SNED1 KIRREL1 TFAP2B	4.74e-04	179	90	4	c7c74e26bbf86c5326ee38bac7de111d5414f46b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX6 FREM2 ANK3 SAMD5	4.74e-04	179	90	4	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ACOT11 PXDNL ACSS1 TFAP2B	4.84e-04	180	90	4	9e09b3dfe344b5d50520711513d389865d73a861
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIRREL1 FGD5 CHD7 SHISA8	4.84e-04	180	90	4	c6030e725e3d86d5d74a1676330c77ffeceb324f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MBOAT1 ANK3 KCNC3 DLG2	4.84e-04	180	90	4	023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SNED1 TMPRSS9 PXDNL SAMD5	4.94e-04	181	90	4	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	severe_influenza-B_memory\|severe_influenza / disease group, cell group and cell class (v2)	MUC16 CHD7 CDCA7L SHISA8	4.94e-04	181	90	4	92e572c92109a6dae0f73138c57c3bbd2e0a2f36
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	FREM2 ANK3 CDH1 CIT	4.94e-04	181	90	4	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBOAT1 INSRR CDH1 TFAP2B	5.05e-04	182	90	4	fe4fb213dc0ca482b0f94097fe1b0a51fc2690e2
ToppCell	Hippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Ndrg2_(MyelinProcesses)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GABRR2 NRAP HSF5	5.09e-04	77	90	3	4720aa099bd00d05b721634eedc9a08b0213ee67
ToppCell	Hippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Ndrg2_(MyelinProcesses)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GABRR2 NRAP HSF5	5.09e-04	77	90	3	25a8dd4cdba4d96d6b0c35fa6310bfff6ce64265
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	FREM2 ANK3 DLG2 CDH1	5.15e-04	183	90	4	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	PND07-28-samps-Epithelial-Alveolar_epithelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	FAT2 ANK3 NECTIN1 CDH1	5.15e-04	183	90	4	23e55f88a802a9299d2773f9394970e86e8bbfaa
ToppCell	PND07-28-samps-Epithelial-Alveolar_epithelial-AT2\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	FAT2 ANK3 NECTIN1 CDH1	5.15e-04	183	90	4	0a69e22750dd8b66ab988cf36d0dd2b59e2f7d26
ToppCell	Control-Epithelial_alveolar-AT_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FREM2 ANK3 MMP7 CDH1	5.26e-04	184	90	4	51e129b3fcc2df083eda05a3afe3717218b1e52b
Disease	sleep disorder (implicated_via_orthology)	INSRR CLOCK TFAP2B	3.61e-06	11	84	3	DOID:535 (implicated_via_orthology)
Disease	Cleft palate with cleft lip	NECTIN1 CDH1	2.85e-04	9	84	2	C0158646
Disease	developmental disorder of mental health (implicated_via_orthology)	GABRR2 NCOR1 DLG2	3.73e-04	49	84	3	DOID:0060037 (implicated_via_orthology)
Disease	cutaneous melanoma	SOX6 CDH1 CDCA7L STN1	4.03e-04	121	84	4	EFO_0000389
Disease	third ventricle volume measurement	GABRR2 ANK3	8.21e-04	15	84	2	EFO_0010335
Disease	cleft lip (is_implicated_in)	NECTIN1 CDH1	8.21e-04	15	84	2	DOID:9296 (is_implicated_in)
Disease	neuroimaging measurement	DIP2B NEFL NCOR1 ANK3 CNKSR3 DLG2 CHD7 MMP7 GABBR1 HTT	9.10e-04	1069	84	10	EFO_0004346
Disease	frailty measurement	ANK3 HTT	1.95e-03	23	84	2	EFO_0009885
Disease	nephrotic syndrome (implicated_via_orthology)	GAPVD1 KIRREL1	2.12e-03	24	84	2	DOID:1184 (implicated_via_orthology)
Disease	Sjogren's syndrome (is_marker_for)	NEFL MUC16	2.12e-03	24	84	2	DOID:12894 (is_marker_for)
Disease	nevus count, cutaneous melanoma	SOX6 TFAP2B STN1	2.26e-03	91	84	3	EFO_0000389, EFO_0004632
Disease	refractive error	ANK3 KIRREL1 DLG2 CHD7 TFAP2B	2.42e-03	326	84	5	MONDO_0004892
Disease	diabetes mellitus (implicated_via_orthology)	INSRR CLOCK	2.49e-03	26	84	2	DOID:9351 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
TSSVEYIHRIGRTGR	DDX52	491	Q9Y2R4
ERDEPGTEVRITYRE	ACSS1	131	Q9NUB1
DLPSTIDEYVHRIGR	DDX4	616	Q9NQI0
NLEYGRDDVRVTHPR	TBC1D32	761	Q96NH3
RRPSRERKESSEHYQ	CCDC77	201	Q9BR77
VTLPTHRETPEYRRG	ACOT11	511	Q8WXI4
HRETPEYRRGETLCS	ACOT11	516	Q8WXI4
VRGVVHVYTRREPDE	AMPD2	326	Q01433
RSRSHERARYEDPTL	BCOR	746	Q6W2J9
IRETGDDYRNITLPH	DCPS	151	Q96C86
ARSTDDRGEPVTHYL	CHD7	891	Q9P2D1
REPSTPHRYREGRTE	CIT	1951	O14578
QLSGLDPRRDYHSVR	TFAP2B	131	Q92481
EHTRSIGPRESAKEY	P3H1	351	Q32P28
YHLTSREITIPRDGT	MUC16	1111	Q8WXI7
YTRDLPHITVDRLVS	MMP7	116	P09237
SPVEREILYHTVART	NCR2	251	O95944
RSGDAESLHRYTLIP	NRAP	1481	Q86VF7
RTPHSERRAVYIGAL	GABBR1	161	Q9UBS5
SEIRHILETRYAVPG	FICD	241	Q9BVA6
ELGVRYRHTAASRSP	FREM2	261	Q5SZK8
HSYPERLVRSRSSDI	GAPVD1	891	Q14C86
VVTGHLDRESEPRYI	FAT2	876	Q9NYQ8
YHGPSRILEVDRRSL	FGD5	686	Q6ZNL6
EERRRATAPPYHDSV	NRG2	566	O14511
GLRYHPIDIETSVSR	DIP2B	1471	Q9P265
LREFETRIGERYITH	PRKD3	841	O94806
IGHRYIEIFRSSRSE	HNRNPH3	81	P31942
RHRISSFRPVEDITE	CDCA7L	316	Q96GN5
VSHQSSVIPDREYLR	PNPO	171	Q9NVS9
ISGVDEHDRPIRTYQ	EPHA10	61	Q5JZY3
RRVGERPLSSYVSVH	PCDHA5	496	Q9Y5H7
RYPERITILRGNHES	PPP2CB	106	P62714
RHRFYRITTPGSERV	MIB1	121	Q86YT6
EPRADGSRRTTRYDI	NDUFS8	131	O00217
YGRRETVPIHDRSAT	PTTG1IP2	136	P0DTF9
ERTGLDSESHYRPEL	PIK3R2	136	O00459
DEHRRPEAITTEGKY	MLXIP	196	Q9HAP2
EYPRRLHGRAVASVT	PXDNL	211	A1KZ92
YVTLTELRRVHPSED	HTT	2721	P42858
TSPIRRYSDIVVHRL	DIS3L	796	Q8TF46
RTEVVHVIRSYDPSA	ANK3	2166	Q12955
RDPYGSLDRHTQTVR	MARVELD2	156	Q8N4S9
RIYLRPGTTSSDVRH	MBOAT1	51	Q6ZNC8
EHIYRLEEVTGTRGR	INSRR	451	P14616
YNVRAHEDRPSSRAV	KIRREL1	606	Q96J84
HTTRPKRDYEVDGRD	DLG2	711	Q15700
LPSDIEEYVHRIGRT	DDX3Y	516	O15523
YRRGIETHTTRQPLR	FAM27D1	131	Q5T7N8
SYTFTVPRRHLERGR	CDH1	36	P12830
GYPRSHILTEEERQD	GABRR2	391	P28476
DPSYRSVQEIREHLR	GPRASP1	1116	Q5JY77
RRVHRYEESEVISLP	MRPS30	161	Q9NP92
DTGLATPARYREHRS	HSF5	551	Q4G112
ETGYSLRRHVDRTSE	PHTF2	341	Q8N3S3
GSIRTYREEREIHAT	STN1	136	Q9H668
RGHTTAPRSRELVSY	SAMD5	111	Q5TGI4
ESSSVVLRYRTPHFR	FAM78A	56	Q5JUQ0
EHIYPTIIGTERDER	PUS1	371	Q9Y606
RGRECIIPDVSRSYH	POMGNT1	486	Q8WZA1
HPGSDRPQERRTSYE	NCOR1	76	O75376
SPSREGHVERLEEIY	PIK3R6	241	Q5UE93
RDPGRERSHTAVYAV	SHISA8	131	B8ZZ34
TTIAYPHEVVRTRLR	SLC25A36	241	Q96CQ1
VRVTREEQSHPARLY	NPRL2	331	Q8WTW4
YPAVGTISETHRRIL	EXTL1	101	Q92935
AYPHEVIRTRLREEG	SLC25A33	251	Q9BSK2
RYPDHSVDRREGSRS	SAFB	756	Q15424
HLYIITSPRDGADRR	SNED1	1191	Q8TER0
RVYRDARGRASSEPH	SOX6	606	P35712
TIQRTHRPSYEDRVC	CLOCK	236	O15516
RPTTERHLVRGADYI	CNKSR3	486	Q6P9H4
AGRPSLLRHDEVRTY	NLN	481	Q9BYT8
RYRPSIRTQERDHTG	ZNF700	176	Q9H0M5
EAYTEHRPEITSRAI	ZER1	361	Q7Z7L7
SEHTRDYRRGIIPTE	RALGAPA1	1911	Q6GYQ0
LPSVVHRDIYRDDIT	SPEN	211	Q96T58
RDPYGEEVDRRSVHS	SEC16A	1336	O15027
YGPELHVALRSRRDE	SNX14	226	Q9Y5W7
SRDRDVYVTTHTPRN	RNF4	101	P78317
SLRRETSDYHRTLTP	TMPRSS9	71	Q7Z410
ELRTVDGPRHDTYIL	TMEM168	486	Q9H0V1
SPNEYHIERRSSRED	TOPAZ1	456	Q8N9V7
YHGRIPREVSETLVQ	SH2D3C	221	Q8N5H7
YIPDAESVRLQRERH	USP31	576	Q70CQ4
YSRGVLSPERHVRTR	PPIP5K2	806	O43314
ASGVLRRTAPREHSY	ZNF185	181	O15231
RRTAPREHSYVLSAA	ZNF185	186	O15231
ETRRYREVVDSRPRH	ZMAT1	251	Q5H9K5
GVRHETYRSTLRTLP	KCNC3	96	Q14003
RRYVETPRVHISSVR	NEFL	16	P07196
TVISRYRLVPSREAH	NECTIN1	206	Q15223