Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	SUMO ligase activity	PIAS3 PIAS2 PIAS1	2.56e-05	20	58	3	GO:0061665
GeneOntologyMolecularFunction	SUMO transferase activity	PIAS3 PIAS2 PIAS1	1.55e-04	36	58	3	GO:0019789
GeneOntologyMolecularFunction	proteoglycan binding	COL2A1 CFH ADA2	4.39e-04	51	58	3	GO:0043394
GeneOntologyMolecularFunction	aminoacyl-tRNA editing activity	IARS2 VARS1	7.38e-04	14	58	2	GO:0002161
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN8A	7.38e-04	14	58	2	GO:0031402
GeneOntologyCellularComponent	extracellular matrix	COL2A1 GPLD1 ADAMTS2 ECM2 COL6A5 TFIP11 TF HCFC1 OTOG	8.64e-05	656	59	9	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL2A1 GPLD1 ADAMTS2 ECM2 COL6A5 TFIP11 TF HCFC1 OTOG	8.84e-05	658	59	9	GO:0030312
MousePheno	abnormal head movements	COL2A1 SELP SCN1A SCN8A OTOG	3.21e-05	103	50	5	MP:0000436
Domain	PINIT	PIAS3 PIAS2 PIAS1	1.13e-07	4	58	3	IPR023321
Domain	PINIT	PIAS3 PIAS2 PIAS1	1.13e-07	4	58	3	PS51466
Domain	PINIT	PIAS3 PIAS2 PIAS1	1.13e-07	4	58	3	PF14324
Domain	zf-MIZ	PIAS3 PIAS2 PIAS1	9.86e-07	7	58	3	PF02891
Domain	ZF_SP_RING	PIAS3 PIAS2 PIAS1	9.86e-07	7	58	3	PS51044
Domain	Znf_MIZ	PIAS3 PIAS2 PIAS1	1.57e-06	8	58	3	IPR004181
Domain	USP_C	USP11 USP15	2.84e-05	3	58	2	IPR029346
Domain	USP7_C2	USP11 USP15	2.84e-05	3	58	2	PF14533
Domain	-	PIAS3 PIAS2 PIAS1	3.63e-05	21	58	3	1.10.720.30
Domain	SAP	PIAS3 PIAS2 PIAS1	4.20e-05	22	58	3	PF02037
Domain	SAP	PIAS3 PIAS2 PIAS1	4.82e-05	23	58	3	SM00513
Domain	Ubiquitin_3	USP11 USP15	5.66e-05	4	58	2	PF14836
Domain	Ub_USP-typ	USP11 USP15	5.66e-05	4	58	2	IPR028135
Domain	SAP	PIAS3 PIAS2 PIAS1	6.23e-05	25	58	3	PS50800
Domain	SAP_dom	PIAS3 PIAS2 PIAS1	6.23e-05	25	58	3	IPR003034
Domain	DUSP	USP11 USP15	1.41e-04	6	58	2	SM00695
Domain	Na_trans_cytopl	SCN1A SCN8A	1.41e-04	6	58	2	PF11933
Domain	Val/Leu/Ile-tRNA-synth_edit	IARS2 VARS1	1.41e-04	6	58	2	IPR009008
Domain	Anticodon_1	IARS2 VARS1	1.41e-04	6	58	2	PF08264
Domain	M/V/L/I-tRNA-synth_anticd-bd	IARS2 VARS1	1.41e-04	6	58	2	IPR013155
Domain	DUSP	USP11 USP15	1.41e-04	6	58	2	PF06337
Domain	-	IARS2 VARS1	1.41e-04	6	58	2	3.90.740.10
Domain	Na_trans_cytopl	SCN1A SCN8A	1.41e-04	6	58	2	IPR024583
Domain	aa-tRNA-synth_Ia	IARS2 VARS1	1.97e-04	7	58	2	IPR002300
Domain	-	USP11 USP15	1.97e-04	7	58	2	3.30.2230.10
Domain	DUSP	USP11 USP15	1.97e-04	7	58	2	PS51283
Domain	tRNA-synt_1	IARS2 VARS1	1.97e-04	7	58	2	PF00133
Domain	Pept_C19_DUSP	USP11 USP15	1.97e-04	7	58	2	IPR006615
Domain	VWF_dom	COL2A1 ECM2 OTOG	2.99e-04	42	58	3	IPR001007
Domain	Na_channel_asu	SCN1A SCN8A	4.20e-04	10	58	2	IPR001696
Domain	Na_trans_assoc	SCN1A SCN8A	4.20e-04	10	58	2	IPR010526
Domain	Na_trans_assoc	SCN1A SCN8A	4.20e-04	10	58	2	PF06512
Domain	Ion_trans_dom	KCNF1 SCN1A TRPC1 SCN8A	4.33e-04	114	58	4	IPR005821
Domain	Ion_trans	KCNF1 SCN1A TRPC1 SCN8A	4.33e-04	114	58	4	PF00520
Domain	-	IARS2 VARS1	5.12e-04	11	58	2	1.10.730.10
Domain	Sushi	SELP CFH F13B	5.64e-04	52	58	3	PF00084
Domain	CCP	SELP CFH F13B	6.30e-04	54	58	3	SM00032
Domain	SUSHI	SELP CFH F13B	7.01e-04	56	58	3	PS50923
Domain	Sushi_SCR_CCP_dom	SELP CFH F13B	7.38e-04	57	58	3	IPR000436
Domain	Channel_four-helix_dom	KCNF1 SCN1A SCN8A	7.38e-04	57	58	3	IPR027359
Domain	-	KCNF1 SCN1A SCN8A	7.38e-04	57	58	3	1.20.120.350
Domain	tRNAsynth_Ia_anticodon-bd	IARS2 VARS1	9.70e-04	15	58	2	IPR009080
Domain	USP_CS	USP11 USP15 USP19	1.13e-03	66	58	3	IPR018200
Domain	USP_1	USP11 USP15 USP19	1.34e-03	70	58	3	PS00972
Domain	UCH	USP11 USP15 USP19	1.40e-03	71	58	3	PF00443
Domain	USP_2	USP11 USP15 USP19	1.40e-03	71	58	3	PS00973
Domain	aa-tRNA-synth_I_CS	IARS2 VARS1	1.40e-03	18	58	2	IPR001412
Domain	USP_3	USP11 USP15 USP19	1.46e-03	72	58	3	PS50235
Domain	USP_dom	USP11 USP15 USP19	1.46e-03	72	58	3	IPR028889
Domain	Peptidase_C19_UCH	USP11 USP15 USP19	1.46e-03	72	58	3	IPR001394
Domain	PRAME_family	PRAMEF7 PRAMEF8	1.57e-03	19	58	2	IPR026271
Domain	AA_TRNA_LIGASE_I	IARS2 VARS1	1.57e-03	19	58	2	PS00178
Domain	Bromodomain_CS	BAZ1A BRPF1	2.94e-03	26	58	2	IPR018359
Domain	VWC	COL2A1 ECM2	3.40e-03	28	58	2	PF00093
Domain	VWFC_1	COL2A1 ECM2	5.58e-03	36	58	2	PS01208
Domain	BROMODOMAIN_1	BAZ1A BRPF1	5.89e-03	37	58	2	PS00633
Domain	EGF_3	SELP TLL1 LRP1B OTOG	6.09e-03	235	58	4	PS50026
Pathway	REACTOME_SUMOYLATION_OF_TRANSCRIPTION_FACTORS	PIAS3 PIAS2 PIAS1	2.14e-05	16	49	3	MM14938
Pathway	REACTOME_SUMOYLATION_OF_TRANSCRIPTION_FACTORS	PIAS3 PIAS2 PIAS1	4.32e-05	20	49	3	M27237
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL2A1 ADAMTS2 TLL1 COL6A5	5.81e-05	61	49	4	MM14637
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL2A1 ADAMTS2 TLL1 COL6A5	8.41e-05	67	49	4	M26999
Pathway	REACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS	PIAS3 PIAS2 PIAS1	1.22e-04	28	49	3	MM15042
Pathway	REACTOME_COLLAGEN_FORMATION	COL2A1 ADAMTS2 TLL1 COL6A5	1.38e-04	76	49	4	MM14573
Pathway	REACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS	PIAS3 PIAS2 PIAS1	1.50e-04	30	49	3	M27323
Pathway	REACTOME_COLLAGEN_FORMATION	COL2A1 ADAMTS2 TLL1 COL6A5	2.64e-04	90	49	4	M631
Pathway	REACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS	PIAS3 PIAS2 PIAS1	3.56e-04	40	49	3	MM15000
Pathway	REACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS	PIAS3 PIAS2 PIAS1	4.73e-04	44	49	3	M27295
Pathway	BIOCARTA_RANBP2_PATHWAY	PIAS2 PIAS1	6.38e-04	11	49	2	M22027
Pathway	KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS	IARS2 VARS1	6.38e-04	11	49	2	M17946
Pathway	PID_RANBP2_PATHWAY	PIAS2 PIAS1	6.38e-04	11	49	2	M140
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL2A1 TLL1 COL6A5	6.90e-04	50	49	3	MM14796
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL2A1 TLL1 COL6A5	1.23e-03	61	49	3	M27103
Pubmed	PIAS genes as disease markers in bipolar disorder.	PIAS3 PIAS2 PIAS1	4.64e-09	3	59	3	30861611
Pubmed	PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases.	PIAS3 PIAS2 PIAS1	4.64e-09	3	59	3	12077349
Pubmed	PIAS proteins are involved in the SUMO-1 modification, intracellular translocation and transcriptional repressive activity of RET finger protein.	PIAS3 PIAS2 PIAS1	4.63e-08	5	59	3	15907835
Pubmed	SUMO-triggered ubiquitination of NR4A1 controls macrophage cell death.	PIAS3 PIAS2 PIAS1	4.63e-08	5	59	3	28622293
Pubmed	SUMO Modification Reverses Inhibitory Effects of Smad Nuclear Interacting Protein-1 in TGF-β Responses.	PIAS3 PIAS2 PIAS1	4.63e-08	5	59	3	27703003
Pubmed	Sumoylation modulates transcriptional activity of MITF in a promoter-specific manner.	PIAS3 PIAS2 PIAS1	9.24e-08	6	59	3	16029420
Pubmed	Inhibition of Stat1-mediated gene activation by PIAS1.	PIAS3 PIAS2 PIAS1	1.62e-07	7	59	3	9724754
Pubmed	Phospho-regulated SUMO interaction modules connect the SUMO system to CK2 signaling.	PIAS3 PIAS2 PIAS1	1.62e-07	7	59	3	19217413
Pubmed	USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor.	USP11 USP15 USP19	2.58e-07	8	59	3	22706160
Pubmed	ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation.	PIAS3 PIAS2 PIAS1	2.58e-07	8	59	3	11117529
Pubmed	Interaction of protein inhibitor of activated STAT (PIAS) proteins with the TATA-binding protein, TBP.	PIAS3 PIAS2 PIAS1	2.58e-07	8	59	3	16522640
Pubmed	A crosstalk between hSiah2 and Pias E3-ligases modulates Pias-dependent activation.	PIAS3 PIAS2 PIAS1	3.87e-07	9	59	3	17533377
Pubmed	Sumoylation of FOXP2 Regulates Motor Function and Vocal Communication Through Purkinje Cell Development.	PIAS3 PIAS2 PIAS1	7.58e-07	11	59	3	27009683
Pubmed	HSP70-Hrd1 axis precludes the oncorepressor potential of N-terminal misfolded Blimp-1s in lymphoma cells.	PIAS3 PIAS2 PIAS1	7.58e-07	11	59	3	28842558
Pubmed	Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis.	PIAS3 PIAS2 PIAS1	1.01e-06	12	59	3	30612578
Pubmed	Foxp1 regulation of neonatal vocalizations via cortical development.	PIAS3 PIAS2 PIAS1	1.31e-06	13	59	3	29138280
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CFH PIAS3 SACS KLHL7 USP11 TFIP11 SORBS1 PIAS2 LRP1B PIAS1 TF VARS1	1.38e-06	1285	59	12	35914814
Pubmed	Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.	SCN1A SCN8A	2.83e-06	2	59	2	37901435
Pubmed	An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.	SCN1A SCN8A	2.83e-06	2	59	2	26410685
Pubmed	Isolation and characterization of the mouse ubiquitin-specific protease Usp15.	USP11 USP15	2.83e-06	2	59	2	12532266
Pubmed	Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.	SCN1A SCN8A	2.83e-06	2	59	2	33411788
Pubmed	The investigation of relevancy between PIAS1 and PIAS2 gene expression and disease severity of multiple sclerosis.	PIAS2 PIAS1	2.83e-06	2	59	2	31084243
Pubmed	Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.	SCN1A SCN8A	2.83e-06	2	59	2	31943325
Pubmed	Super-resolution study of PIAS SUMO E3-ligases in hippocampal and cortical neurons.	PIAS3 PIAS1	2.83e-06	2	59	2	34459572
Pubmed	Expression of PIAS Genes in Migraine Patients.	PIAS2 PIAS1	2.83e-06	2	59	2	33763841
Pubmed	Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.	SCN1A SCN8A	2.83e-06	2	59	2	37665666
Pubmed	The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.	SCN1A SCN8A	2.83e-06	2	59	2	17881658
Pubmed	Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides.	CFH GPLD1 TF F13B	3.17e-06	59	59	4	17330941
Pubmed	Specification of SUMO1- and SUMO2-interacting motifs.	PIAS3 PIAS2 PIAS1	6.98e-06	22	59	3	16524884
Pubmed	Cloning and analysis of a murine PIAS family member, PIASgamma, in developing skin and neurons.	PIAS3 PIAS1	8.48e-06	3	59	2	10854042
Pubmed	Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.	SCN1A SCN8A	8.48e-06	3	59	2	32845893
Pubmed	Evolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11.	USP11 USP15	8.48e-06	3	59	2	26503449
Pubmed	Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.	SCN1A SCN8A	8.48e-06	3	59	2	28518218
Pubmed	Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.	SCN1A SCN8A	8.48e-06	3	59	2	24704313
Pubmed	The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels.	SCN1A SCN8A	8.48e-06	3	59	2	28117367
Pubmed	Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.	SCN1A SCN8A	8.48e-06	3	59	2	17928448
Pubmed	Structural variability of the ubiquitin specific protease DUSP-UBL double domains.	USP11 USP15	8.48e-06	3	59	2	22001210
Pubmed	Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.	SCN1A SCN8A	8.48e-06	3	59	2	26182346
Pubmed	De novo SCN1A, SCN8A, and CLCN2 mutations in childhood absence epilepsy.	SCN1A SCN8A	8.48e-06	3	59	2	31054517
Pubmed	Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways.	CFH ADAMTS2 PIAS2 PIAS1 TF	1.36e-05	179	59	5	18624398
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN8A	1.69e-05	4	59	2	17537961
Pubmed	Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.	SCN1A SCN8A	1.69e-05	4	59	2	35031483
Pubmed	DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor.	PIAS3 PIAS2	1.69e-05	4	59	2	11477070
Pubmed	The transactivating function of peroxisome proliferator-activated receptor gamma is negatively regulated by SUMO conjugation in the amino-terminal domain.	PIAS2 PIAS1	1.69e-05	4	59	2	15507114
Pubmed	Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.	SCN1A SCN8A	1.69e-05	4	59	2	29578003
Pubmed	Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity.	PIAS3 PIAS1	1.69e-05	4	59	2	15961505
Pubmed	FLI-1 functionally interacts with PIASxalpha, a member of the PIAS E3 SUMO ligase family.	PIAS2 PIAS1	1.69e-05	4	59	2	16148010
Pubmed	Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.	SCN1A SCN8A	1.69e-05	4	59	2	21156207
Pubmed	Genome-Wide Association Mapping for Female Infertility in Inbred Mice.	SORBS1 PLCE1	1.69e-05	4	59	2	27449513
Pubmed	SUMOylation modulates the transcription repressor function of RIP140.	PIAS3 PIAS1	1.69e-05	4	59	2	18211901
Pubmed	Transcriptional activity of peroxisome proliferator-activated receptor gamma is modulated by SUMO-1 modification.	PIAS2 PIAS1	1.69e-05	4	59	2	15123625
Pubmed	Protein inhibitors of activated STAT resemble scaffold attachment factors and function as interacting nuclear receptor coregulators.	PIAS2 PIAS1	1.69e-05	4	59	2	11877418
Pubmed	Association between the development of the body axis and the craniofacial skeleton studied by immunohistochemical analyses using collagen II, Pax9, Pax1, and Noggin antibodies.	COL2A1 NOG	1.69e-05	4	59	2	18594453
Pubmed	Models for discovery of targeted therapy in genetic epileptic encephalopathies.	SCN1A SCN8A	1.69e-05	4	59	2	28742937
Pubmed	PIAS proteins promote SUMO-1 conjugation to STAT1.	PIAS3 PIAS1	1.69e-05	4	59	2	12855578
Pubmed	Detecting Genes and Gene-gene Interactions for Age-related Macular Degeneration with a Forest-based Approach.	CFH BBS9	1.69e-05	4	59	2	20161521
Pubmed	Severity of Demyelinating and Axonal Neuropathy Mouse Models Is Modified by Genes Affecting Structure and Function of Peripheral Nodes.	SH3TC2 SCN8A	1.69e-05	4	59	2	28355569
Pubmed	SUMOylation of the corepressor N-CoR modulates its capacity to repress transcription.	PIAS3 PIAS1	1.69e-05	4	59	2	16421255
Pubmed	Distinct effects of PIAS proteins on androgen-mediated gene activation in prostate cancer cells.	PIAS2 PIAS1	1.69e-05	4	59	2	11439351
Pubmed	PAPILLARY THYROID CANCER IS CHARACTERIZED BY ALTERED EXPRESSION OF GENES INVOLVED IN THE SUMOYLATION PROCESS.	PIAS2 PIAS1	2.82e-05	5	59	2	26403403
Pubmed	SUMO-1 modification of centrosomal protein hNinein promotes hNinein nuclear localization.	PIAS2 PIAS1	2.82e-05	5	59	2	16154161
Pubmed	PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription.	PIAS2 PIAS1	2.82e-05	5	59	2	12177000
Pubmed	Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity.	PIAS2 PIAS1	2.82e-05	5	59	2	23202365
Pubmed	Regulation of cardiac specific nkx2.5 gene activity by small ubiquitin-like modifier.	PIAS2 PIAS1	2.82e-05	5	59	2	18579533
Pubmed	Molecular cloning of the b subunit of mouse coagulation factor XIII and assignment of the gene to chromosome 1: close evolutionary relationship to complement factor H.	CFH F13B	2.82e-05	5	59	2	8468048
Pubmed	SUMO E3 ligases are expressed in the retina and regulate SUMOylation of the metabotropic glutamate receptor 8b.	PIAS3 PIAS1	2.82e-05	5	59	2	21288202
Pubmed	PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1.	COL2A1 TLL1	2.82e-05	5	59	2	12393877
Pubmed	Control of peroxisome proliferator-activated receptor gamma2 stability and activity by SUMOylation.	PIAS2 PIAS1	2.82e-05	5	59	2	15229330
Pubmed	Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP.	PIAS3 PIAS2 PIAS1	3.75e-05	38	59	3	28680062
Pubmed	Pias1 interaction and sumoylation of metabotropic glutamate receptor 8.	PIAS2 PIAS1	4.23e-05	6	59	2	16144832
Pubmed	The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA.	PIAS2 PIAS1	4.23e-05	6	59	2	22406621
Pubmed	Repression of the Transactivating Capacity of the Oncoprotein PLAG1 by SUMOylation.	PIAS2 PIAS1	4.23e-05	6	59	2	15208321
Pubmed	Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity.	PIAS2 PIAS1	4.23e-05	6	59	2	11867732
Pubmed	SUMOylation of RORalpha potentiates transcriptional activation function.	PIAS3 PIAS2	4.23e-05	6	59	2	19041634
Pubmed	The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration.	CFH F13B	4.23e-05	6	59	2	18541031
Pubmed	Sumoylation of peroxisome proliferator-activated receptor gamma by apoptotic cells prevents lipopolysaccharide-induced NCoR removal from kappaB binding sites mediating transrepression of proinflammatory cytokines.	PIAS2 PIAS1	4.23e-05	6	59	2	18832723
Pubmed	A novel role for protein inhibitor of activated STAT (PIAS) proteins in modulating the activity of Zimp7, a novel PIAS-like protein, in androgen receptor-mediated transcription.	PIAS3 PIAS1	4.23e-05	6	59	2	20159969
Pubmed	A SUMOylation-dependent pathway regulates SIRT1 transcription and lung cancer metastasis.	PIAS3 PIAS2	4.23e-05	6	59	2	23704280
Pubmed	Regulation of procollagen amino-propeptide processing during mouse embryogenesis by specialization of homologous ADAMTS proteases: insights on collagen biosynthesis and dermatosparaxis.	COL2A1 ADAMTS2	4.23e-05	6	59	2	16556917
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN1A SCN8A	4.23e-05	6	59	2	23652591
Pubmed	Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes.	COL2A1 NOG	4.23e-05	6	59	2	21624478
Pubmed	Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2.	PIAS3 PIAS2 PIAS1	4.72e-05	41	59	3	18157088
Pubmed	SUMOylation of Csk Negatively Modulates its Tumor Suppressor Function.	PIAS3 PIAS1	5.91e-05	7	59	2	31125786
Pubmed	ZNF451 is a novel PML body- and SUMO-associated transcriptional coregulator.	PIAS2 PIAS1	5.91e-05	7	59	2	18656483
Pubmed	Precise spatial restriction of BMP signaling is essential for articular cartilage differentiation.	COL2A1 NOG	5.91e-05	7	59	2	25758226
Pubmed	Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.	SCN1A SCN8A	5.91e-05	7	59	2	25818041
Pubmed	An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity.	PIAS2 PIAS1	5.91e-05	7	59	2	17283066
Pubmed	RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation.	PIAS2 PIAS1	5.91e-05	7	59	2	22162396
Pubmed	Human cystathionine beta-synthase is a target for sumoylation.	PIAS3 PIAS1	5.91e-05	7	59	2	17087506
Pubmed	Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules.	PIAS2 PIAS1	5.91e-05	7	59	2	14609633
Pubmed	Regulation of Sox9 by Sonic Hedgehog (Shh) is essential for patterning and formation of tracheal cartilage.	COL2A1 NOG	5.91e-05	7	59	2	20034104
Pubmed	Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.	SCN1A SCN8A	5.91e-05	7	59	2	15272007
Pubmed	Regulation of skeletal progenitor differentiation by the BMP and retinoid signaling pathways.	COL2A1 NOG	5.91e-05	7	59	2	10684250
Pubmed	Functional proteomics mapping of a human signaling pathway.	THSD7A PIAS3 CDC123 BAZ1A PIAS2 PIAS1 PRPF40A	6.27e-05	591	59	7	15231748
Pubmed	Phosphorylation-dependent interaction of SATB1 and PIAS1 directs SUMO-regulated caspase cleavage of SATB1.	PIAS3 PIAS1	7.87e-05	8	59	2	20351170
Pubmed	Tissue interaction is required for glenoid fossa development during temporomandibular joint formation.	COL2A1 NOG	7.87e-05	8	59	2	21953591
Pubmed	Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription.	PIAS2 PIAS1	7.87e-05	8	59	2	14752048
Pubmed	SUMO E3 ligase activity of TRIM proteins.	PIAS2 PIAS1	7.87e-05	8	59	2	20972456
Pubmed	Sumoylation of Mdm2 by protein inhibitor of activated STAT (PIAS) and RanBP2 enzymes.	PIAS2 PIAS1	7.87e-05	8	59	2	12393906
Pubmed	SUMO-1 modification of the C-terminal KVEKVD of Axin is required for JNK activation but has no effect on Wnt signaling.	PIAS2 PIAS1	7.87e-05	8	59	2	12223491
Interaction	PGR interactions	PIAS3 SORBS1 USP15 PIAS2 PIAS1	3.94e-06	84	57	5	int:PGR
Interaction	DNAJC10 interactions	PDIA4 IARS2 CDC123 USP11 USP15 LRP1B PRPF40A	8.37e-06	260	57	7	int:DNAJC10
Interaction	SIAH2 interactions	PIAS3 PIAS2 PIAS1 USP19 PLCE1	1.12e-05	104	57	5	int:SIAH2
Interaction	SIAH1 interactions	PIAS3 PIAS2 PIAS1 HCFC1 USP19 PLCE1	3.89e-05	223	57	6	int:SIAH1
Interaction	GOLM1 interactions	THSD7A CDC123 CNPY3 NIPSNAP3A TF	5.58e-05	145	57	5	int:GOLM1
Interaction	SEL1L interactions	PDIA4 CDC123 CNPY3 USP15 USP19	5.58e-05	145	57	5	int:SEL1L
Interaction	HOOK1 interactions	PPP2R3A CDC123 BRPF1 TFIP11 PIAS2 LRP1B	5.85e-05	240	57	6	int:HOOK1
Interaction	CHAD interactions	COL2A1 CNPY3	7.82e-05	5	57	2	int:CHAD
Cytoband	3q22.1	PPP2R3A COL6A5 TF	2.35e-05	42	60	3	3q22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr3q22	PPP2R3A COL6A5 TF	7.53e-04	135	60	3	chr3q22
Cytoband	1p36.21	PRAMEF7 PRAMEF8	3.12e-03	63	60	2	1p36.21
Cytoband	1q41	BPNT1 IARS2	3.41e-03	66	60	2	1q41
Cytoband	Ensembl 112 genes in cytogenetic band chr2q22	LRP1B NXPH2	3.83e-03	70	60	2	chr2q22
Cytoband	Ensembl 112 genes in cytogenetic band chr1q31	CFH F13B	4.38e-03	75	60	2	chr1q31
GeneFamily	Zinc fingers MIZ-type	PIAS3 PIAS2 PIAS1	5.36e-07	7	46	3	85
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN8A	2.25e-04	9	46	2	1203
GeneFamily	Ubiquitin specific peptidases	USP11 USP15 USP19	3.89e-04	56	46	3	366
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELP CFH F13B	4.10e-04	57	46	3	1179
GeneFamily	Aminoacyl tRNA synthetases, Class I	IARS2 VARS1	1.05e-03	19	46	2	131
GeneFamily	PRAME family	PRAMEF7 PRAMEF8	1.69e-03	24	46	2	686
GeneFamily	Collagens	COL2A1 COL6A5	6.10e-03	46	46	2	490
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5\|TCGA-Skin / Sample_Type by Project: Shred V9	PDIA4 THSD7A KCNF1 OSMR LRP1B PLCE1	1.48e-07	178	60	6	ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	SELP CFH SH3TC2 NOG THSD7A LRP1B	2.31e-07	192	60	6	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	COVID-19-kidney-Mito-rich_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL2A1 THSD7A TLL1 PAX4 OTOG	1.54e-06	145	60	5	afed661aef990edb8e7012ab67ace56443520c9f
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Tpbg\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NOG THSD7A TLL1 MYPN NXPH2	2.81e-06	164	60	5	f0499e6c1b17c4df72b18b294e3b53ef723da2ac
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 ZNF182 ECM2 TRPC1 LRP1B	2.90e-06	165	60	5	0edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 ZNF182 ECM2 TRPC1 LRP1B	2.90e-06	165	60	5	fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Tpbg\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NOG THSD7A TLL1 MYPN NXPH2	2.98e-06	166	60	5	b4241f8d2a0aa910dbb0d0d5d3631a9b73453fe9
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 ZFHX4 LRP1B OTOG PLCE1	4.93e-06	184	60	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 ZFHX4 LRP1B OTOG PLCE1	4.93e-06	184	60	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 ZFHX4 LRP1B OTOG PLCE1	4.93e-06	184	60	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COPD-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	SELP NOG THSD7A TLL1 OSMR	5.33e-06	187	60	5	be42ee71d3412bb1f52593d8814de85c354a0efa
ToppCell	Control-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	SELP SH3TC2 TLL1 SORBS1 OSMR	5.62e-06	189	60	5	f83f7521e377ded1522639e9a35c98b3e2725bac
ToppCell	Control-Endothelial-VE_Venous\|Control / Disease state, Lineage and Cell class	SELP SH3TC2 TLL1 SORBS1 OSMR	5.91e-06	191	60	5	617546cf4883dedf3323e03a53ba5adec334cf8e
ToppCell	COPD-Endothelial-VE_Arterial\|COPD / Disease state, Lineage and Cell class	SELP NOG THSD7A TLL1 OSMR	6.22e-06	193	60	5	1c701b6ab5f0f0239634adac94fa1c92bf3c36f4
ToppCell	Control-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	SELP SH3TC2 NOG THSD7A TLL1	6.22e-06	193	60	5	52c0f2c7af57436f23e0c0e0c87086c47695e2c4
ToppCell	Control-Endothelial-VE_Arterial\|Control / Disease state, Lineage and Cell class	SELP NOG THSD7A TLL1 OSMR	6.54e-06	195	60	5	56c66a3655820961e1390b8f4bcc5618e8d0c5a8
ToppCell	Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	CFH ZFHX4 ADAMTS2 ECM2 OSMR	7.22e-06	199	60	5	40de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 TLL1 COL6A5 LRP1B	6.43e-05	160	60	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 TLL1 COL6A5 LRP1B	6.43e-05	160	60	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D122\|Adult / Lineage, Cell type, age group and donor	SACS ECM2 SORBS1 HCFC1	6.59e-05	161	60	4	64891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFHX4 ECM2 SCN1A PLCE1	6.59e-05	161	60	4	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFHX4 ECM2 SCN1A PLCE1	6.59e-05	161	60	4	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFHX4 ECM2 SCN1A PLCE1	6.59e-05	161	60	4	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	BPNT1 ADAMTS2 SORBS1 OSMR	6.75e-05	162	60	4	68c40d12689cc1b6c797e6e48173f0110f8144e4
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFHX4 ECM2 SCN1A PLCE1	6.75e-05	162	60	4	96c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	BPNT1 ADAMTS2 SORBS1 OSMR	6.75e-05	162	60	4	735fa3f77b31a4189e431d05c326403c18cbbffb
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 THSD7A ADAMTS2 ECM2	7.25e-05	165	60	4	f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_CCDC184\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CCNG2 F13B PMFBP1 PLCE1	7.59e-05	167	60	4	ef3ef83c213e818597600da15764c5b37763d7b6
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NOG TLL1 MYPN NXPH2	7.77e-05	168	60	4	2572a3dd4f3f619bd26a3cd6e60de43821d8bb64
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH KCNF1 TRPC1 COL6A5	8.90e-05	174	60	4	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL2A1 SACS ECM2 SCN8A	9.10e-05	175	60	4	8b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GPLD1 NOG ADAMTS2 PRAMEF8	9.10e-05	175	60	4	1d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL2A1 SACS ECM2 SCN8A	9.10e-05	175	60	4	a5db428b078938627e61b7e944c1e0c1d61ac2da
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GPLD1 NOG ADAMTS2 PRAMEF8	9.10e-05	175	60	4	427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D175\|Adult / Lineage, Cell type, age group and donor	SELP THSD7A TLL1 LRP1B	9.10e-05	175	60	4	0a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KCNF1 SCN1A SORBS1 OSMR	9.10e-05	175	60	4	e99e145a152f534b75267ec492a252a0b814b4f8
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL2A1 ZFHX4 ECM2 PIAS2	9.10e-05	175	60	4	085cceb1fc2c4ae2f27e85cea5702defecc2cf44
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELP CFH THSD7A TLL1	9.51e-05	177	60	4	6f6cf93893daac6ae228df36219ee3acf8de8f97
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH ZFHX4 ADAMTS2 SORBS1	9.72e-05	178	60	4	d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYPN TACR2 SORBS1 LRP1B	9.72e-05	178	60	4	8ec2a25dda96c9cc9c2904b6cb18f75a293f4969
ToppCell	Adult-Epithelial-club_cell-D122\|Adult / Lineage, Cell type, age group and donor	CFH TLL1 LRP1B PLCE1	9.72e-05	178	60	4	35a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYPN TACR2 SORBS1 LRP1B	9.72e-05	178	60	4	6c91331196696e0cf239d105f458e3230659fa38
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CCNG2 THSD7A NXPH2 PLCE1	1.04e-04	181	60	4	062f00736eed96e4f4327615d093558dd7d82b20
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH ADAMTS2 ECM2 COL6A5	1.04e-04	181	60	4	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH ADAMTS2 ECM2 COL6A5	1.04e-04	181	60	4	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	wk_20-22-Mesenchymal-Chondrocyte-intermediate_chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL2A1 CFH PPP2R3A SORBS1	1.08e-04	183	60	4	1464b5c4425e8776c4aeb4d2b560481d4bf13931
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SELP THSD7A TLL1 OSMR	1.08e-04	183	60	4	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CFH SH3TC2 TLL1 NXPH2	1.13e-04	185	60	4	492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ZFHX4 ADAMTS2 SORBS1 OSMR	1.17e-04	187	60	4	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A ECM2 OSMR IL1RL2	1.17e-04	187	60	4	e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELP CFH THSD7A TLL1	1.20e-04	188	60	4	524d1d928c9386acf20e53d31894107dd7290dc7
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELP CFH THSD7A TLL1	1.20e-04	188	60	4	f5a2f324f3f6c5078d57130392d3f1ba74f29094
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZFHX4 ECM2 TLL1 PLCE1	1.20e-04	188	60	4	dc52dd2957be3f40001f0a56f3d9ac9d66ea466e
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZFHX4 ECM2 TLL1 PLCE1	1.20e-04	188	60	4	2ef08313087e91985bcffc46c3798470cdeec49c
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZFHX4 ECM2 TLL1 PLCE1	1.20e-04	188	60	4	1f1604b6dc0a8ad0be3d9aac0bef448459c22465
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH THSD7A ADAMTS2 ECM2	1.20e-04	188	60	4	bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELP CFH THSD7A TLL1	1.20e-04	188	60	4	1b57995d70cf81212e8d46dfaf44dbaf9c7bc4d5
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELP CFH THSD7A TLL1	1.20e-04	188	60	4	cd2d1f8e43c252dd8730a5758458ef63e7ffc836
ToppCell	5'-Airway_Nasal-Endothelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELP CFH THSD7A TLL1	1.20e-04	188	60	4	6c9d5e4014f807149328ff4eabd5e86dfe18094d
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL2A1 ZFHX4 ECM2 PLCE1	1.22e-04	189	60	4	eccf3d49354a67c94f1ed7c15a98a48a5e8e2ed0
ToppCell	facs-Kidney-nan-3m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAMTS2 ECM2 COL6A5	1.22e-04	189	60	4	a5306561026e4dfcc39beeb785e5108ac595d136
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	CFH THSD7A TLL1 OSMR	1.22e-04	189	60	4	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL2A1 ZFHX4 ECM2 PLCE1	1.22e-04	189	60	4	40764f461b8aa1d3a2c5a30590b7fb9307d47d09
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ECM2 TRPC1 SCN8A PLCE1	1.22e-04	189	60	4	26cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCell	facs-Kidney-nan-3m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAMTS2 ECM2 COL6A5	1.22e-04	189	60	4	302b950a6ad578f8aeff7ea6fd15fe631225287d
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SELP CFH THSD7A TLL1	1.22e-04	189	60	4	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	facs-Kidney-nan-3m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAMTS2 ECM2 COL6A5	1.22e-04	189	60	4	381058f55908f84375b54601d617389ef43ab855
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ECM2 TRPC1 SCN8A PLCE1	1.25e-04	190	60	4	2ab604d35456beba71c25511e0f819000e6642d2
ToppCell	COVID-19-Heart-EC_3\|Heart / Disease (COVID-19 only), tissue and cell type	SELP THSD7A TLL1 OSMR	1.25e-04	190	60	4	78e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCell	COVID-19-Endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SELP THSD7A TLL1 SORBS1	1.25e-04	190	60	4	9fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	SELP SH3TC2 NOG THSD7A	1.27e-04	191	60	4	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH ADAMTS2 ECM2 SORBS1	1.27e-04	191	60	4	a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	PPP2R3A KLHL7 MYPN SORBS1	1.27e-04	191	60	4	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL2A1 ZFHX4 ECM2 PLCE1	1.27e-04	191	60	4	5271198116343c07202649889057e5774d7fdde3
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH ZFHX4 ECM2 SORBS1	1.27e-04	191	60	4	2c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCell	facs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A ECM2 TLL1 PLCE1	1.27e-04	191	60	4	48823a97c38263f2c6e58348214f5b62773a6368
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH ADAMTS2 ECM2 SORBS1	1.27e-04	191	60	4	8f6d592edc32fdb901af30501d4360512334e8c2
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A ECM2 TLL1 PLCE1	1.27e-04	191	60	4	0eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	SELP CFH THSD7A TLL1	1.30e-04	192	60	4	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAMTS2 COL6A5 OSMR	1.30e-04	192	60	4	853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAMTS2 COL6A5 OSMR	1.30e-04	192	60	4	d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH ZFHX4 ADAMTS2 ECM2	1.30e-04	192	60	4	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAMTS2 ECM2 IL1RL2	1.30e-04	192	60	4	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH ADAMTS2 ECM2 OSMR	1.30e-04	192	60	4	7a2e79490e4f7058bb76b46c45b5df9f729e3146
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH ZFHX4 ADAMTS2 SORBS1	1.30e-04	192	60	4	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL2A1 ZFHX4 SCN1A LRP1B	1.30e-04	192	60	4	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAMTS2 COL6A5 OSMR	1.30e-04	192	60	4	49281626ecad0456fdbded2378b7028d7b589686
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH ADAMTS2 ECM2 IL1RL2	1.30e-04	192	60	4	7b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCell	facs-Trachea-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH ADAMTS2 ECM2 OSMR	1.30e-04	192	60	4	e8af6ad1ae99cae13a82d0d8d7f38af9b777f0ba
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAMTS2 ECM2 IL1RL2	1.30e-04	192	60	4	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH ADAMTS2 ECM2 OSMR	1.30e-04	192	60	4	fc940f91ff8e051631dbf25e6e8d73cf8337eccb
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	CFH THSD7A TLL1 OSMR	1.33e-04	193	60	4	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	droplet-Heart-nan-24m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH CCNG2 ADAMTS2 ECM2	1.33e-04	193	60	4	d08919db9601941569b9a143dad4d8e6f56a4389
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP THSD7A TLL1 OSMR	1.33e-04	193	60	4	c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	SELP THSD7A TLL1 OSMR	1.33e-04	193	60	4	194e7fa00a50cc4e026987b715323d125d79594e
ToppCell	IPF-Endothelial-VE_Venous\|IPF / Disease state, Lineage and Cell class	SELP TLL1 SORBS1 OSMR	1.33e-04	193	60	4	29a655fa80feaabe846c90a28363b037e22d24ae
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH ZFHX4 ADAMTS2 SORBS1	1.33e-04	193	60	4	5b602b1702283184bd3943c2a6f2290b7c37e407
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH ZFHX4 ECM2 SORBS1	1.33e-04	193	60	4	09a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	SELP THSD7A TLL1 OSMR	1.33e-04	193	60	4	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	facs-MAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH THSD7A ZFHX4 ECM2	1.33e-04	193	60	4	733f557bdc80293b40ccdf560f1675793df932d6
Disease	hematologic cancer (implicated_via_orthology)	PIAS3 PIAS2 PIAS1	1.73e-06	13	55	3	DOID:2531 (implicated_via_orthology)
Disease	BMP-binding endothelial regulator protein measurement	CFH BBS9	3.41e-06	2	55	2	EFO_0020183
Disease	retinal detachment (is_implicated_in)	COL2A1 CFH	3.41e-06	2	55	2	DOID:5327 (is_implicated_in)
Disease	dementia, Parkinson disease, disease progression measurement	BBS9 LRP1B	1.02e-05	3	55	2	EFO_0008336, MONDO_0001627, MONDO_0005180
Disease	potassium voltage-gated channel subfamily F member 1 measurement	CFH TF	3.40e-05	5	55	2	EFO_0802890
Disease	mediator of RNA polymerase II transcription subunit 1 measurement	CFH CNPY3	5.09e-05	6	55	2	EFO_0008228
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN8A	1.52e-04	10	55	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN8A	1.52e-04	10	55	2	DOID:0080422 (implicated_via_orthology)
Disease	transmembrane glycoprotein NMB measurement	CFH KLHL7	1.52e-04	10	55	2	EFO_0008303
Disease	receptor-interacting serine/threonine-protein kinase 2 measurement	CFH ECM2	1.86e-04	11	55	2	EFO_0802997
Disease	craniosynostosis (is_implicated_in)	NOG BBS9	2.22e-04	12	55	2	DOID:2340 (is_implicated_in)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN8A	2.22e-04	12	55	2	DOID:0060170 (implicated_via_orthology)
Disease	T-cell surface glycoprotein CD3 epsilon chain measurement	SELP CFH	2.63e-04	13	55	2	EFO_0802114
Disease	intraocular pressure measurement	PPP2R3A THSD7A ADAMTS2 TLL1 NDUFAF6 BBS9	3.62e-04	509	55	6	EFO_0004695
Disease	cortical surface area change measurement, age at assessment	USP15 TF	5.72e-04	19	55	2	EFO_0008007, EFO_0021503
Disease	optic disc size measurement	SELP MYPN LRP1B PLCE1	5.85e-04	205	55	4	EFO_0004832
Disease	gestational age, birth measurement	COL2A1 PPP2R3A	7.00e-04	21	55	2	EFO_0005112, EFO_0006921
Disease	complement factor H-like 1 protein measurement	CFH THSD7A	7.69e-04	22	55	2	EFO_0600092
Disease	chronic kidney disease	THSD7A ECM2 MYPN COL6A5	9.73e-04	235	55	4	EFO_0003884
Disease	Malignant mesothelioma	ADAMTS2 OSMR TF	1.12e-03	109	55	3	C0345967
Disease	aortic measurement	CFH TLL1 USP15 PLCE1	1.24e-03	251	55	4	EFO_0020865
Disease	complement factor H-related protein 2 measurement	CFH F13B	1.34e-03	29	55	2	EFO_0600055
Disease	osteoarthritis, hip, body mass index	COL2A1 NOG	1.44e-03	30	55	2	EFO_0004340, EFO_1000786
Disease	HbA1c measurement	COL2A1 CDC123 MYPN NDUFAF6 TACR2 PAX4	1.57e-03	675	55	6	EFO_0004541
Disease	word list delayed recall measurement, memory performance	ADA2 PIAS1	1.74e-03	33	55	2	EFO_0004874, EFO_0006805
Disease	primary dental caries	CFH TLL1	1.84e-03	34	55	2	EFO_0600095

Protein segments in the cluster

Peptide	Gene	Start	Entry
DCKPWYCDKPPSKYI	FAM47DP	16	A6NHR8
SSPECCKPDLKKLVW	CCNG2	256	Q16589
EKWSHPPSCIKTDCL	CFH	976	P08603
PGCKKWDTCAPEVIL	BPNT1	241	O95861
YEWALKKWSPCSKPC	ADAMTS2	856	O95450
KLKTVPEGDWFCPEC	BAZ1A	1181	Q9NRL2
YNDKDVWKPEPCRIC	COL2A1	41	P02458
SWLCSKPFKVICIYI	NXPH2	221	O95156
SEITYLVPWCKLEKP	NIPSNAP3A	126	Q9UFN0
LKSQWIKETCYPDIP	OSMR	761	Q99650
VCCKDLWYLETEKPP	HCFC1	351	P51610
DCQDLPVSYKCKCWP	LRP1B	2941	Q9NZR2
CTTEGWSPEPRCFKK	F13B	76	P05160
WSPEPRCFKKCTKPD	F13B	81	P05160
ECLTYGWSLTPKCTK	F13B	196	P05160
FWKKTVEDIYCDNPP	NDUFAF6	116	Q330K2
PKDYSWTDIRCPFEK	KLHL7	311	Q8IXQ5
KIAKVCGCPLYWKAP	PPP2R3A	751	Q06190
KKLDWSPSCFLPYCS	BBS9	281	Q3SYG4
LSDTPPKACLKPCWD	PAX4	291	O43316
FTTLKCECPAYLPWL	DDO	136	Q99489
CECPAYLPWLEKRIK	DDO	141	Q99489
TPAEQLLSKCPWKEY	PRPF40A	176	O75400
PKSCVLGPIKWYKDC	IL1RL2	151	Q9HB29
PDPCIEYELVLRKWC	CDC123	156	O75794
DWVRLPSKCEVCKYV	CNPY3	41	Q9BT09
LREHSPCWKEKCPAY	COL6A5	1741	A8TX70
PCWKEKCPAYPTELV	COL6A5	1746	A8TX70
TYSWKKDIPIEVCPI	ADA2	396	Q9NZK5
YNKAVWSPEPCTTCL	ECM2	111	O94769
CVEIYIKSPSAPGKW	SELP	131	P16109
CCPWELSTLVKFAPY	PRAMEF8	211	Q5VWM4
LPAKSLCYNDCPWIK	SACS	2461	Q9NZJ4
LCYNDCPWIKVKDTT	SACS	2466	Q9NZJ4
AFRCCPWVTPTKEDK	TACR2	321	P21452
TPKEKECEELKSCPW	PRR14L	266	Q5THK1
PTWICPVCDKKAAYE	PIAS2	381	O75928
GWIPIQYPIISECKC	NOG	216	Q13253
FLPEECPCTWKGKEY	OTOG	941	Q6ZRI0
DKEPCCLPQWSVPKD	PMFBP1	861	Q8TBY8
LCVTPYPEPSECSWK	VARS1	1086	P26640
PDKYPSRKECTWEIS	TLL1	791	O43897
IPCEEPACYDWKAVR	THSD7A	566	Q9UPZ6
LPCKKDCIVTPYSDW	THSD7A	766	Q9UPZ6
CGYVLKPPVLWDKNC	PLCE1	1836	Q9P212
EDCYLKTLSLCPPWL	SH3TC2	1186	Q8TF17
DPKKDVLIEFYAPWC	PDIA4	541	P13667
PTTKEKCPRCWKYTA	IARS2	981	Q9NSE4
TWVCPVCDKKAPYEH	PIAS1	371	O75925
ELEESRQKCPPCWYK	SCN1A	726	P35498
HIPPARWKLTCYICK	BRPF1	376	P55201
KPTWTCPVCDKKAPY	PIAS3	361	Q9Y6X2
KLWLSYFDDKCTLPP	TRPC1	666	P48995
CCPWELSTLVKFAPY	PRAMEF7	211	Q5VXH5
PKQKPTWRCEVCDYE	ZFHX4	761	Q86UP3
EVLAPEEAWYCPQCK	USP19	1071	O94966
PYECPVCWKAFSQKS	ZNF182	541	P17025
PEAPTDECKPVKWCA	TF	351	P02787
KEVYKDPPLCAWEAN	SMRP1	26	Q8NCR6
PKKIWDYTPGDCSIL	SORBS1	581	Q9BX66
KSWITPCPEEKAQYV	GPLD1	776	P80108
TTKEKLGAEDPWYCP	USP15	796	Q9Y4E8
ELEESQRKCPPCWYK	SCN8A	711	Q9UQD0
VETLEKENPWYCPSC	USP11	791	P51784
PLKDCTYGTEIISKW	TFIP11	441	Q9UBB9
KCVWKFLEKPESSCP	KCNF1	166	Q9H3M0
PVFYWKKDNETIPCT	MYPN	1201	Q86TC9