Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium ion binding	LRP4 CASR LTBP1 LTBP3 LRP1B AGRN LDLR FBN3 NOTCH1 NOTCH4	1.13e-07	749	31	10	GO:0005509
GeneOntologyMolecularFunction	extracellular matrix structural constituent	LAMB1 LTBP1 MUC2 MUC4 AGRN FBN3	3.89e-07	188	31	6	GO:0005201
GeneOntologyMolecularFunction	transforming growth factor beta binding	LTBP1 LTBP3 AGRN	8.60e-06	26	31	3	GO:0050431
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP1B LDLR	2.76e-04	16	31	2	GO:0005041
GeneOntologyMolecularFunction	structural molecule activity	LAMB1 LTBP1 MUC2 MUC4 AGRN FBN3 OTOG	3.53e-04	891	31	7	GO:0005198
GeneOntologyMolecularFunction	phosphoric diester hydrolase activity	CASR SMPD1 PDE6B	4.53e-04	97	31	3	GO:0008081
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LRP1B LDLR	4.81e-04	21	31	2	GO:0030228
GeneOntologyMolecularFunction	Notch binding	NOTCH1 NOTCH4	7.99e-04	27	31	2	GO:0005112
GeneOntologyMolecularFunction	phospholipase C activity	CASR SMPD1	9.23e-04	29	31	2	GO:0004629
GeneOntologyMolecularFunction	growth factor binding	LTBP1 LTBP3 AGRN	1.79e-03	156	31	3	GO:0019838
GeneOntologyMolecularFunction	cytokine binding	LTBP1 LTBP3 AGRN	1.82e-03	157	31	3	GO:0019955
GeneOntologyMolecularFunction	molecular function inhibitor activity	LTBP1 MDFI SPINT1 AGRN NOTCH1	2.08e-03	596	31	5	GO:0140678
GeneOntologyMolecularFunction	extracellular matrix binding	LTBP1 AGRN	5.72e-03	73	31	2	GO:0050840
GeneOntologyMolecularFunction	cargo receptor activity	LRP1B LDLR	7.69e-03	85	31	2	GO:0038024
GeneOntologyBiologicalProcess	receptor clustering	LRP4 SLITRK3 NRXN2 AGRN	7.06e-06	83	31	4	GO:0043113
GeneOntologyBiologicalProcess	positive regulation of aorta morphogenesis	NOTCH1 NOTCH4	1.31e-05	4	31	2	GO:1903849
GeneOntologyBiologicalProcess	gephyrin clustering involved in postsynaptic density assembly	SLITRK3 NRXN2	2.18e-05	5	31	2	GO:0097116
GeneOntologyBiologicalProcess	regulation of aorta morphogenesis	NOTCH1 NOTCH4	3.27e-05	6	31	2	GO:1903847
GeneOntologyBiologicalProcess	artery development	LTBP1 LDLR NOTCH1 NOTCH4	4.54e-05	133	31	4	GO:0060840
GeneOntologyBiologicalProcess	positive regulation of transcription of Notch receptor target	NOTCH1 NOTCH4	4.57e-05	7	31	2	GO:0007221
GeneOntologyBiologicalProcess	negative regulation of ossification	LRP4 LTBP3 NOTCH1	5.74e-05	50	31	3	GO:0030279
GeneOntologyBiologicalProcess	amyloid-beta clearance by cellular catabolic process	LRP4 LDLR	6.09e-05	8	31	2	GO:0150094
GeneOntologyBiologicalProcess	positive regulation of artery morphogenesis	NOTCH1 NOTCH4	7.82e-05	9	31	2	GO:1905653
GeneOntologyBiologicalProcess	postsynaptic membrane organization	LRP4 NRXN2 AGRN	8.07e-05	56	31	3	GO:0001941
GeneOntologyBiologicalProcess	negative regulation of cell-cell adhesion mediated by cadherin	NOTCH1 NOTCH4	9.76e-05	10	31	2	GO:2000048
GeneOntologyBiologicalProcess	postsynaptic membrane assembly	LRP4 NRXN2	1.19e-04	11	31	2	GO:0097104
GeneOntologyBiologicalProcess	synaptic assembly at neuromuscular junction	LRP4 AGRN	1.19e-04	11	31	2	GO:0051124
GeneOntologyBiologicalProcess	positive regulation of skeletal muscle acetylcholine-gated channel clustering	LRP4 AGRN	1.43e-04	12	31	2	GO:1904395
GeneOntologyBiologicalProcess	neuron projection morphogenesis	LRP4 LAMB1 SPRY3 SLITRK3 AGRN ATP8A2 NOTCH1	1.52e-04	802	31	7	GO:0048812
GeneOntologyBiologicalProcess	venous blood vessel morphogenesis	NOTCH1 NOTCH4	1.69e-04	13	31	2	GO:0048845
GeneOntologyBiologicalProcess	axonogenesis	LRP4 LAMB1 SLITRK3 AGRN ATP8A2 NOTCH1	1.71e-04	566	31	6	GO:0007409
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	LRP4 LAMB1 SPRY3 SLITRK3 AGRN ATP8A2 NOTCH1	1.73e-04	819	31	7	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	LRP4 LAMB1 SPRY3 SLITRK3 AGRN ATP8A2 NOTCH1	1.82e-04	826	31	7	GO:0048858
GeneOntologyBiologicalProcess	regulation of skeletal muscle acetylcholine-gated channel clustering	LRP4 AGRN	2.27e-04	15	31	2	GO:1904393
GeneOntologyBiologicalProcess	regulation of synapse assembly	LRP4 SLITRK3 NRXN2 AGRN	2.28e-04	202	31	4	GO:0051963
GeneOntologyBiologicalProcess	aorta development	LTBP1 NOTCH1 NOTCH4	2.34e-04	80	31	3	GO:0035904
GeneOntologyBiologicalProcess	negative regulation of cell adhesion molecule production	NOTCH1 NOTCH4	2.59e-04	16	31	2	GO:0060354
GeneOntologyBiologicalProcess	behavior	LAMB1 CASR NRXN2 AGRN LDLR ATP8A2 OTOG	2.90e-04	891	31	7	GO:0007610
GeneOntologyBiologicalProcess	regulation of nervous system development	LRP4 SLITRK3 SPINT1 AGRN LDLR NOTCH1	2.91e-04	625	31	6	GO:0051960
GeneOntologyBiologicalProcess	regulation of artery morphogenesis	NOTCH1 NOTCH4	2.93e-04	17	31	2	GO:1905651
GeneOntologyBiologicalProcess	regulation of postsynaptic neurotransmitter receptor activity	NRXN2 NOTCH1	2.93e-04	17	31	2	GO:0098962
GeneOntologyBiologicalProcess	cell morphogenesis	LRP4 LAMB1 SPRY3 SLITRK3 AGRN ATP8A2 NOTCH1 NOTCH4	2.94e-04	1194	31	8	GO:0000902
GeneOntologyBiologicalProcess	positive regulation of Rac protein signal transduction	LRP4 AGRN	3.29e-04	18	31	2	GO:0035022
GeneOntologyBiologicalProcess	axon development	LRP4 LAMB1 SLITRK3 AGRN ATP8A2 NOTCH1	3.36e-04	642	31	6	GO:0061564
GeneOntologyBiologicalProcess	artery morphogenesis	LDLR NOTCH1 NOTCH4	3.53e-04	92	31	3	GO:0048844
GeneOntologyBiologicalProcess	positive regulation of small GTPase mediated signal transduction	LRP4 AGRN NOTCH1	3.53e-04	92	31	3	GO:0051057
GeneOntologyBiologicalProcess	postsynapse assembly	LRP4 SLITRK3 NRXN2	3.64e-04	93	31	3	GO:0099068
GeneOntologyBiologicalProcess	positive regulation of receptor clustering	LRP4 AGRN	3.68e-04	19	31	2	GO:1903911
GeneOntologyBiologicalProcess	venous blood vessel development	NOTCH1 NOTCH4	4.08e-04	20	31	2	GO:0060841
GeneOntologyBiologicalProcess	morphogenesis of a branching epithelium	CASR SPINT1 NOTCH1 NOTCH4	4.12e-04	236	31	4	GO:0061138
GeneOntologyBiologicalProcess	regulation of cell-cell adhesion mediated by cadherin	NOTCH1 NOTCH4	4.51e-04	21	31	2	GO:2000047
GeneOntologyBiologicalProcess	skeletal muscle acetylcholine-gated channel clustering	LRP4 AGRN	4.51e-04	21	31	2	GO:0071340
GeneOntologyBiologicalProcess	neuron projection development	LRP4 LAMB1 SPRY3 SLITRK3 AGRN ATP8A2 NOTCH1 OTOG	4.82e-04	1285	31	8	GO:0031175
GeneOntologyBiologicalProcess	regulation of glial cell differentiation	SPINT1 LDLR NOTCH1	5.05e-04	104	31	3	GO:0045685
GeneOntologyBiologicalProcess	positive regulation of muscle cell differentiation	LAMB1 NOTCH1 NOTCH4	5.34e-04	106	31	3	GO:0051149
GeneOntologyBiologicalProcess	regulation of cell adhesion molecule production	NOTCH1 NOTCH4	5.42e-04	23	31	2	GO:0060353
GeneOntologyBiologicalProcess	morphogenesis of a branching structure	CASR SPINT1 NOTCH1 NOTCH4	5.77e-04	258	31	4	GO:0001763
GeneOntologyBiologicalProcess	maintenance of gastrointestinal epithelium	MUC2 MUC4	5.91e-04	24	31	2	GO:0030277
GeneOntologyBiologicalProcess	negative regulation of molecular function	SPRY3 PRMT2 SMPD1 MDFI SPINT1 AGRN NOTCH1	6.00e-04	1005	31	7	GO:0044092
GeneOntologyBiologicalProcess	positive regulation of apoptotic process	PRMT2 SMPD1 TNFRSF10A MUC2 AGRN NOTCH1	6.09e-04	718	31	6	GO:0043065
GeneOntologyBiologicalProcess	entrainment of circadian clock by photoperiod	FBXL17 PDE6B	6.42e-04	25	31	2	GO:0043153
GeneOntologyBiologicalProcess	cell adhesion molecule production	NOTCH1 NOTCH4	6.95e-04	26	31	2	GO:0060352
GeneOntologyBiologicalProcess	response to abiotic stimulus	FBXL17 PRMT2 CASR SMPD1 NRXN2 PDE6B ATP8A2 NOTCH1	7.07e-04	1361	31	8	GO:0009628
GeneOntologyBiologicalProcess	positive regulation of programmed cell death	PRMT2 SMPD1 TNFRSF10A MUC2 AGRN NOTCH1	7.09e-04	739	31	6	GO:0043068
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	LRP4 LAMB1 SLITRK3 AGRN ATP8A2 NOTCH1	7.55e-04	748	31	6	GO:0048667
GeneOntologyBiologicalProcess	motor neuron apoptotic process	TNFRSF10A AGRN	8.06e-04	28	31	2	GO:0097049
GeneOntologyBiologicalProcess	positive regulation of smooth muscle cell differentiation	NOTCH1 NOTCH4	8.06e-04	28	31	2	GO:0051152
GeneOntologyBiologicalProcess	photoperiodism	FBXL17 PDE6B	8.06e-04	28	31	2	GO:0009648
GeneOntologyBiologicalProcess	regulation of receptor clustering	LRP4 AGRN	8.65e-04	29	31	2	GO:1903909
GeneOntologyBiologicalProcess	digestive system process	MUC2 MUC4 LDLR	8.83e-04	126	31	3	GO:0022600
GeneOntologyBiologicalProcess	entrainment of circadian clock	FBXL17 PDE6B	9.26e-04	30	31	2	GO:0009649
GeneOntologyBiologicalProcess	negative regulation of biomineral tissue development	LTBP3 NOTCH1	1.05e-03	32	31	2	GO:0070168
GeneOntologyBiologicalProcess	synapse assembly	LRP4 SLITRK3 NRXN2 AGRN	1.12e-03	308	31	4	GO:0007416
GeneOntologyBiologicalProcess	regulation of cell junction assembly	LRP4 SLITRK3 NRXN2 AGRN	1.13e-03	309	31	4	GO:1901888
GeneOntologyBiologicalProcess	neuron development	LRP4 LAMB1 SPRY3 SLITRK3 AGRN ATP8A2 NOTCH1 OTOG	1.14e-03	1463	31	8	GO:0048666
GeneOntologyBiologicalProcess	regulation of MAPK cascade	SPRY3 CASR SMPD1 MDFI TNFRSF10A NOTCH1	1.18e-03	815	31	6	GO:0043408
GeneOntologyBiologicalProcess	postsynapse organization	LRP4 SLITRK3 NRXN2 AGRN	1.18e-03	313	31	4	GO:0099173
GeneOntologyBiologicalProcess	postsynaptic density assembly	SLITRK3 NRXN2	1.19e-03	34	31	2	GO:0097107
GeneOntologyBiologicalProcess	regulation of Rac protein signal transduction	LRP4 AGRN	1.26e-03	35	31	2	GO:0035020
GeneOntologyBiologicalProcess	epithelial structure maintenance	MUC2 MUC4	1.33e-03	36	31	2	GO:0010669
GeneOntologyBiologicalProcess	regulation of ossification	LRP4 LTBP3 NOTCH1	1.38e-03	147	31	3	GO:0030278
GeneOntologyBiologicalProcess	response to auditory stimulus	NRXN2 ATP8A2	1.41e-03	37	31	2	GO:0010996
GeneOntologyBiologicalProcess	cellular response to growth factor stimulus	SPRY3 CASR LTBP1 LTBP3 SPINT1 NOTCH1	1.46e-03	850	31	6	GO:0071363
GeneOntologyBiologicalProcess	regulation of gliogenesis	SPINT1 LDLR NOTCH1	1.49e-03	151	31	3	GO:0014013
GeneOntologyBiologicalProcess	regulation of small GTPase mediated signal transduction	LRP4 SPRY3 AGRN NOTCH1	1.49e-03	333	31	4	GO:0051056
GeneOntologyBiologicalProcess	anatomical structure homeostasis	LTBP3 MUC2 MUC4 NOTCH1	1.50e-03	334	31	4	GO:0060249
GeneOntologyBiologicalProcess	tissue homeostasis	LTBP3 MUC2 MUC4 NOTCH1	1.50e-03	334	31	4	GO:0001894
GeneOntologyBiologicalProcess	cellular response to low-density lipoprotein particle stimulus	CASR LDLR	1.56e-03	39	31	2	GO:0071404
GeneOntologyBiologicalProcess	negative regulation of glial cell differentiation	LDLR NOTCH1	1.56e-03	39	31	2	GO:0045686
GeneOntologyBiologicalProcess	viral life cycle	SMPD1 SPINT1 LDLR NOTCH1	1.61e-03	340	31	4	GO:0019058
GeneOntologyBiologicalProcess	amyloid-beta clearance	LRP4 LDLR	1.65e-03	40	31	2	GO:0097242
GeneOntologyBiologicalProcess	response to lipoprotein particle	CASR LDLR	1.65e-03	40	31	2	GO:0055094
GeneOntologyBiologicalProcess	aorta morphogenesis	NOTCH1 NOTCH4	1.73e-03	41	31	2	GO:0035909
GeneOntologyBiologicalProcess	digestion	MUC2 MUC4 LDLR	1.76e-03	160	31	3	GO:0007586
GeneOntologyBiologicalProcess	response to growth factor	SPRY3 CASR LTBP1 LTBP3 SPINT1 NOTCH1	1.78e-03	883	31	6	GO:0070848
GeneOntologyBiologicalProcess	biological process involved in symbiotic interaction	SMPD1 SPINT1 MUC2 LDLR	1.80e-03	351	31	4	GO:0044403
GeneOntologyBiologicalProcess	negative regulation of developmental process	LRP4 SPRY3 LTBP3 TMEM215 LDLR NOTCH1 NOTCH4	1.87e-03	1220	31	7	GO:0051093
GeneOntologyBiologicalProcess	cellular response to lipoprotein particle stimulus	CASR LDLR	1.90e-03	43	31	2	GO:0071402
GeneOntologyBiologicalProcess	regulation of astrocyte differentiation	LDLR NOTCH1	1.90e-03	43	31	2	GO:0048710
GeneOntologyBiologicalProcess	rhythmic process	FBXL17 PDE6B AGRN NOTCH1	1.98e-03	360	31	4	GO:0048511
GeneOntologyBiologicalProcess	regulation of postsynapse assembly	LRP4 NRXN2	1.99e-03	44	31	2	GO:0150052
GeneOntologyBiologicalProcess	postsynaptic specialization assembly	SLITRK3 NRXN2	1.99e-03	44	31	2	GO:0098698
GeneOntologyBiologicalProcess	symbiont entry into host cell	SMPD1 SPINT1 LDLR	2.05e-03	169	31	3	GO:0046718
GeneOntologyBiologicalProcess	excitatory synapse assembly	SLITRK3 NRXN2	2.17e-03	46	31	2	GO:1904861
GeneOntologyBiologicalProcess	negative regulation of neurogenesis	LRP4 LDLR NOTCH1	2.19e-03	173	31	3	GO:0050768
GeneOntologyBiologicalProcess	negative regulation of cell adhesion	LAMB1 MUC4 NOTCH1 NOTCH4	2.29e-03	375	31	4	GO:0007162
GeneOntologyCellularComponent	extracellular matrix	LAMB1 LTBP1 LTBP3 MUC2 MUC4 AGRN SPON2 FBN3 OTOG	3.03e-07	656	31	9	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	LAMB1 LTBP1 LTBP3 MUC2 MUC4 AGRN SPON2 FBN3 OTOG	3.11e-07	658	31	9	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	LAMB1 LTBP1 LTBP3 MUC2 MUC4 AGRN	1.11e-04	530	31	6	GO:0062023
GeneOntologyCellularComponent	cell surface	LRP4 CASR SLITRK3 TNFRSF10A AGRN LDLR NOTCH1 NOTCH4	1.64e-04	1111	31	8	GO:0009986
GeneOntologyCellularComponent	microfibril	LTBP1 FBN3	1.64e-04	13	31	2	GO:0001527
GeneOntologyCellularComponent	Golgi lumen	MUC2 MUC4 AGRN	5.57e-04	109	31	3	GO:0005796
GeneOntologyCellularComponent	endolysosome	SMPD1 LDLR	9.02e-04	30	31	2	GO:0036019
GeneOntologyCellularComponent	apical part of cell	CASR MUC4 LDLR NOTCH1 OTOG	1.65e-03	592	31	5	GO:0045177
GeneOntologyCellularComponent	apical plasma membrane	CASR MUC4 NOTCH1 OTOG	5.56e-03	487	31	4	GO:0016324
MousePheno	abnormal posture	LRP4 LAMB1 CASR SMPD1 NRXN2 ATP8A2 OTOG	1.62e-07	243	25	7	MP:0001504
MousePheno	failure of neuromuscular synapse presynaptic differentiation	LRP4 AGRN	4.59e-05	6	25	2	MP:0001054
MousePheno	increased macrophage derived foam cell number	SMPD1 LDLR	6.41e-05	7	25	2	MP:0004778
MousePheno	foam cell reticulosis	SMPD1 LDLR	6.41e-05	7	25	2	MP:0009841
MousePheno	abnormal macrophage derived foam cell morphology	SMPD1 LDLR	8.54e-05	8	25	2	MP:0008243
MousePheno	decreased circulating unsaturated transferrin level	LRP1B LDLR	8.54e-05	8	25	2	MP:0011897
MousePheno	decreased circulating transferrin level	LRP1B LDLR	1.37e-04	10	25	2	MP:0011894
MousePheno	abnormal somatic nervous system morphology	LRP4 CASR PDE6B AGRN LDLR ATP8A2 NOTCH1 OTOG	2.85e-04	1025	25	8	MP:0002752
Domain	EGF-like_dom	LRP4 LAMB1 LTBP1 LTBP3 C9 NRXN2 MUC4 LRP1B AGRN LDLR FBN3 NOTCH1 NOTCH4 OTOG	8.42e-19	249	31	14	IPR000742
Domain	EGF_3	LRP4 LTBP1 LTBP3 C9 NRXN2 MUC4 LRP1B AGRN LDLR FBN3 NOTCH1 NOTCH4 OTOG	2.40e-17	235	31	13	PS50026
Domain	EGF_1	LRP4 LAMB1 LTBP1 LTBP3 C9 NRXN2 MUC4 LRP1B AGRN LDLR FBN3 NOTCH1 NOTCH4	6.99e-17	255	31	13	PS00022
Domain	EGF-like_CS	LRP4 LAMB1 LTBP1 LTBP3 C9 NRXN2 MUC4 LRP1B AGRN LDLR FBN3 NOTCH1 NOTCH4	9.48e-17	261	31	13	IPR013032
Domain	EGF_2	LRP4 LAMB1 LTBP1 LTBP3 C9 NRXN2 MUC4 LRP1B AGRN LDLR FBN3 NOTCH1 NOTCH4	1.16e-16	265	31	13	PS01186
Domain	EGF	LRP4 LAMB1 LTBP1 LTBP3 NRXN2 MUC4 LRP1B AGRN LDLR FBN3 NOTCH1 NOTCH4	1.36e-15	235	31	12	SM00181
Domain	Growth_fac_rcpt_	LRP4 LAMB1 LTBP1 LTBP3 C9 LRP1B LDLR FBN3 NOTCH1 NOTCH4	4.71e-14	156	31	10	IPR009030
Domain	EGF_CA	LRP4 LTBP1 LTBP3 LRP1B AGRN LDLR FBN3 NOTCH1 NOTCH4	2.87e-13	122	31	9	SM00179
Domain	EGF-like_Ca-bd_dom	LRP4 LTBP1 LTBP3 LRP1B AGRN LDLR FBN3 NOTCH1 NOTCH4	3.33e-13	124	31	9	IPR001881
Domain	EGF	LRP4 LTBP1 NRXN2 MUC4 LRP1B AGRN FBN3 NOTCH1 NOTCH4	3.85e-13	126	31	9	PF00008
Domain	EGF_CA	LRP4 LTBP1 LTBP3 LRP1B LDLR FBN3 NOTCH1 NOTCH4	1.05e-12	86	31	8	PF07645
Domain	EGF_Ca-bd_CS	LRP4 LTBP1 LTBP3 LRP1B LDLR FBN3 NOTCH1 NOTCH4	2.82e-12	97	31	8	IPR018097
Domain	EGF_CA	LRP4 LTBP1 LTBP3 LRP1B LDLR FBN3 NOTCH1 NOTCH4	3.33e-12	99	31	8	PS01187
Domain	ASX_HYDROXYL	LRP4 LTBP1 LTBP3 LRP1B LDLR FBN3 NOTCH1 NOTCH4	3.62e-12	100	31	8	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	LRP4 LTBP1 LTBP3 LRP1B LDLR FBN3 NOTCH1 NOTCH4	5.83e-12	106	31	8	IPR000152
Domain	cEGF	LRP4 LTBP1 LTBP3 LRP1B FBN3	5.76e-10	26	31	5	IPR026823
Domain	cEGF	LRP4 LTBP1 LTBP3 LRP1B FBN3	5.76e-10	26	31	5	PF12662
Domain	LDLR_class-A_CS	LRP4 C9 SPINT1 LRP1B LDLR	5.67e-09	40	31	5	IPR023415
Domain	Ldl_recept_a	LRP4 C9 SPINT1 LRP1B LDLR	1.05e-08	45	31	5	PF00057
Domain	-	LRP4 C9 SPINT1 LRP1B LDLR	1.17e-08	46	31	5	4.10.400.10
Domain	LDLRA_1	LRP4 C9 SPINT1 LRP1B LDLR	1.46e-08	48	31	5	PS01209
Domain	LDrepeatLR_classA_rpt	LRP4 C9 SPINT1 LRP1B LDLR	1.63e-08	49	31	5	IPR002172
Domain	LDLa	LRP4 C9 SPINT1 LRP1B LDLR	1.63e-08	49	31	5	SM00192
Domain	LDLRA_2	LRP4 C9 SPINT1 LRP1B LDLR	1.63e-08	49	31	5	PS50068
Domain	hEGF	LTBP3 FBN3 NOTCH1 NOTCH4	1.24e-07	28	31	4	PF12661
Domain	TB	LTBP1 LTBP3 FBN3	1.44e-07	7	31	3	PF00683
Domain	-	LTBP1 LTBP3 FBN3	2.31e-07	8	31	3	3.90.290.10
Domain	TB	LTBP1 LTBP3 FBN3	3.45e-07	9	31	3	PS51364
Domain	TB_dom	LTBP1 LTBP3 FBN3	3.45e-07	9	31	3	IPR017878
Domain	Ldl_recept_b	LRP4 LRP1B LDLR	1.49e-06	14	31	3	PF00058
Domain	LDLRB	LRP4 LRP1B LDLR	1.49e-06	14	31	3	PS51120
Domain	LY	LRP4 LRP1B LDLR	1.86e-06	15	31	3	SM00135
Domain	LDLR_classB_rpt	LRP4 LRP1B LDLR	1.86e-06	15	31	3	IPR000033
Domain	VWFD	MUC2 MUC4 OTOG	2.28e-06	16	31	3	PS51233
Domain	VWD	MUC2 MUC4 OTOG	2.28e-06	16	31	3	SM00216
Domain	VWF_type-D	MUC2 MUC4 OTOG	2.28e-06	16	31	3	IPR001846
Domain	VWD	MUC2 MUC4 OTOG	2.28e-06	16	31	3	PF00094
Domain	NOD	NOTCH1 NOTCH4	1.60e-05	4	31	2	PF06816
Domain	Notch	NOTCH1 NOTCH4	1.60e-05	4	31	2	IPR008297
Domain	NODP	NOTCH1 NOTCH4	1.60e-05	4	31	2	PF07684
Domain	Notch_NODP_dom	NOTCH1 NOTCH4	1.60e-05	4	31	2	IPR011656
Domain	Notch_NOD_dom	NOTCH1 NOTCH4	1.60e-05	4	31	2	IPR010660
Domain	NOD	NOTCH1 NOTCH4	1.60e-05	4	31	2	SM01338
Domain	NODP	NOTCH1 NOTCH4	1.60e-05	4	31	2	SM01339
Domain	LNR	NOTCH1 NOTCH4	2.66e-05	5	31	2	PS50258
Domain	-	LRP4 LRP1B LDLR	3.63e-05	39	31	3	2.120.10.30
Domain	Notch_dom	NOTCH1 NOTCH4	5.57e-05	7	31	2	IPR000800
Domain	Notch	NOTCH1 NOTCH4	5.57e-05	7	31	2	PF00066
Domain	NL	NOTCH1 NOTCH4	5.57e-05	7	31	2	SM00004
Domain	6-blade_b-propeller_TolB-like	LRP4 LRP1B LDLR	5.99e-05	46	31	3	IPR011042
Domain	TIL	MUC2 OTOG	1.74e-04	12	31	2	PF01826
Domain	C8	MUC2 OTOG	1.74e-04	12	31	2	PF08742
Domain	Unchr_dom_Cys-rich	MUC2 OTOG	2.06e-04	13	31	2	IPR014853
Domain	C8	MUC2 OTOG	2.06e-04	13	31	2	SM00832
Domain	TIL_dom	MUC2 OTOG	2.40e-04	14	31	2	IPR002919
Domain	VWC_out	MUC2 OTOG	4.48e-04	19	31	2	SM00215
Domain	CT	MUC2 OTOG	6.03e-04	22	31	2	SM00041
Domain	Cys_knot_C	MUC2 OTOG	7.81e-04	25	31	2	IPR006207
Domain	CTCK_2	MUC2 OTOG	7.81e-04	25	31	2	PS01225
Domain	EGF_LAM_2	LAMB1 AGRN	1.13e-03	30	31	2	PS50027
Domain	EGF_LAM_1	LAMB1 AGRN	1.13e-03	30	31	2	PS01248
Domain	Laminin_EGF	LAMB1 AGRN	1.53e-03	35	31	2	PF00053
Domain	EGF_Lam	LAMB1 AGRN	1.53e-03	35	31	2	SM00180
Domain	LAM_G_DOMAIN	NRXN2 AGRN	1.81e-03	38	31	2	PS50025
Domain	Laminin_EGF	LAMB1 AGRN	1.81e-03	38	31	2	IPR002049
Domain	VWF_dom	MUC2 OTOG	2.20e-03	42	31	2	IPR001007
Domain	LamG	NRXN2 AGRN	2.42e-03	44	31	2	SM00282
Domain	Laminin_G	NRXN2 AGRN	4.16e-03	58	31	2	IPR001791
Domain	EGF_extracell	LRP1B NOTCH1	4.44e-03	60	31	2	IPR013111
Domain	EGF_2	LRP1B NOTCH1	4.44e-03	60	31	2	PF07974
Domain	TSP_1	C9 SPON2	4.89e-03	63	31	2	PF00090
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	MUC4 AGRN SPON2 NOTCH1 NOTCH4	6.75e-06	143	27	5	M27275
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	MUC4 SPON2 NOTCH1 NOTCH4	7.99e-06	68	27	4	M27303
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	LRP4 LAMB1 LTBP1 LTBP3 AGRN FBN3	1.79e-05	300	27	6	M610
Pathway	REACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3	NOTCH1 NOTCH4	3.52e-05	5	27	2	M27411
Pathway	REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI	NOTCH1 NOTCH4	3.52e-05	5	27	2	MM14733
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	LTBP1 LTBP3 FBN3	4.66e-05	37	27	3	M27134
Pathway	REACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM	NOTCH1 NOTCH4	5.27e-05	6	27	2	M27068
Pathway	REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING	NOTCH1 NOTCH4	7.38e-05	7	27	2	MM14734
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	LTBP1 LTBP3 FBN3	7.88e-05	44	27	3	M26969
Pathway	KEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA	LTBP1 LTBP3	9.82e-05	8	27	2	M47850
Pathway	REACTOME_DISEASES_OF_METABOLISM	MUC4 AGRN SPON2 NOTCH1 NOTCH4	9.89e-05	250	27	5	M27554
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION	NOTCH1 NOTCH4	1.92e-04	11	27	2	M47865
Pathway	KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380	NOTCH1 NOTCH4	2.30e-04	12	27	2	M47532
Pathway	KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381	NOTCH1 NOTCH4	2.30e-04	12	27	2	M47533
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY	NOTCH1 NOTCH4	2.72e-04	13	27	2	M47423
Pathway	KEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382	NOTCH1 NOTCH4	2.72e-04	13	27	2	M47534
Pathway	REACTOME_ECM_PROTEOGLYCANS	LRP4 LAMB1 AGRN	4.01e-04	76	27	3	M27219
Pathway	KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY	NOTCH1 NOTCH4	4.17e-04	16	27	2	M47424
Pathway	REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI	NOTCH1 NOTCH4	5.30e-04	18	27	2	M614
Pathway	REACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	NOTCH1 NOTCH4	6.57e-04	20	27	2	M27881
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC2 MUC4	7.25e-04	21	27	2	MM15706
Pathway	REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY	NOTCH1 NOTCH4	8.72e-04	23	27	2	MM14954
Pathway	REACTOME_VISUAL_PHOTOTRANSDUCTION	PDE6B AGRN LDLR	8.95e-04	100	27	3	M27158
Pathway	KEGG_DORSO_VENTRAL_AXIS_FORMATION	NOTCH1 NOTCH4	9.50e-04	24	27	2	M11190
Pathway	WP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE	LTBP1 FBN3	1.03e-03	25	27	2	M39713
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	MUC2 MUC4 SPON2	1.15e-03	109	27	3	MM15164
Pathway	WP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING	NOTCH1 NOTCH4	1.20e-03	27	27	2	M39545
Pathway	PID_TRAIL_PATHWAY	SMPD1 TNFRSF10A	1.29e-03	28	27	2	M79
Pathway	REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY	NOTCH1 NOTCH4	1.29e-03	28	27	2	M6177
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	LTBP1 LTBP3	1.69e-03	32	27	2	MM14854
Pathway	WP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT	NOTCH1 NOTCH4	1.91e-03	34	27	2	M39390
Pathway	KEGG_PRION_DISEASES	C9 NOTCH1	2.02e-03	35	27	2	M13036
Pathway	WP_NEOVASCULARIZATION_PROCESSES	NOTCH1 NOTCH4	2.26e-03	37	27	2	M39506
Pathway	WP_GENETIC_CAUSES_OF_PORTOSINUSOIDAL_VASCULAR_DISEASE	NOTCH1 NOTCH4	2.26e-03	37	27	2	M45513
Pathway	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS	LTBP1 LTBP3	2.38e-03	38	27	2	MM14874
Pathway	REACTOME_SIGNALING_BY_NOTCH	NOTCH1 NOTCH4	2.51e-03	39	27	2	MM14604
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	LTBP1 LTBP3	2.51e-03	39	27	2	MM14601
Pathway	WP_NOTCH_SIGNALING_WP268	NOTCH1 NOTCH4	3.32e-03	45	27	2	M39571
Pathway	WP_NOTCH_SIGNALING_PATHWAY	NOTCH1 NOTCH4	3.47e-03	46	27	2	MM15971
Pathway	KEGG_NOTCH_SIGNALING_PATHWAY	NOTCH1 NOTCH4	3.62e-03	47	27	2	M7946
Pathway	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS	LTBP1 LTBP3	3.62e-03	47	27	2	M646
Pathway	REACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS	AGRN LDLR	3.77e-03	48	27	2	M27642
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	LRP4 LAMB1 SMPD1 LTBP1 LTBP3 ERGIC3 LRP1B AGRN LDLR NOTCH1	5.32e-08	1201	31	10	35696571
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	LAMB1 LTBP1 LTBP3 AGRN NOTCH1	6.54e-08	118	31	5	21078624
Pubmed	Introduction to Notch signaling.	NOTCH1 NOTCH4	7.69e-07	2	31	2	25053477
Pubmed	Differential patterns of NOTCH1-4 receptor expression are markers of glioma cell differentiation.	NOTCH1 NOTCH4	7.69e-07	2	31	2	24305720
Pubmed	Acid Sphingomyelinase Deficiency Prevents Diet-induced Hepatic Triacylglycerol Accumulation and Hyperglycemia in Mice.	SMPD1 LDLR	7.69e-07	2	31	2	19074137
Pubmed	Notch signaling in cancer.	NOTCH1 NOTCH4	7.69e-07	2	31	2	12496471
Pubmed	Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy.	NOTCH1 NOTCH4	7.69e-07	2	31	2	23389453
Pubmed	Notch signaling: from the outside in.	NOTCH1 NOTCH4	7.69e-07	2	31	2	11112321
Pubmed	Clinicopathological significance of aberrant Notch receptors in intrahepatic cholangiocarcinoma.	NOTCH1 NOTCH4	7.69e-07	2	31	2	25031748
Pubmed	Thymosin beta4 induces angiogenesis through Notch signaling in endothelial cells.	NOTCH1 NOTCH4	7.69e-07	2	31	2	23749167
Pubmed	Amitriptyline inhibits nonalcoholic steatohepatitis and atherosclerosis induced by high-fat diet and LPS through modulation of sphingolipid metabolism.	SMPD1 LDLR	7.69e-07	2	31	2	31821039
Pubmed	Critical role of endothelial Notch1 signaling in postnatal angiogenesis.	NOTCH1 NOTCH4	7.69e-07	2	31	2	17158336
Pubmed	Notch-1 and Notch-4 biomarker expression in triple-negative breast cancer.	NOTCH1 NOTCH4	7.69e-07	2	31	2	22084425
Pubmed	Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses.	LRP4 AGRN	7.69e-07	2	31	2	22854782
Pubmed	Notch-1 and notch-4 receptors as prognostic markers in breast cancer.	NOTCH1 NOTCH4	7.69e-07	2	31	2	20444726
Pubmed	Elevation of ceramide in serum lipoproteins during acute phase response in humans and mice: role of serine-palmitoyl transferase.	SMPD1 LDLR	7.69e-07	2	31	2	14592455
Pubmed	Notch1 and Notch4 are markers for poor prognosis of hepatocellular carcinoma.	NOTCH1 NOTCH4	7.69e-07	2	31	2	23742774
Pubmed	Agrin binds to the nerve-muscle basal lamina via laminin.	LAMB1 AGRN	7.69e-07	2	31	2	9151673
Pubmed	Hepatitis B virus X protein activates Notch signaling by its effects on Notch1 and Notch4 in human hepatocellular carcinoma.	NOTCH1 NOTCH4	7.69e-07	2	31	2	26530164
Pubmed	AGRN promotes lung adenocarcinoma progression by activating Notch signaling pathway and acts as a therapeutic target.	AGRN NOTCH1	7.69e-07	2	31	2	37321467
Pubmed	MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.	LRP4 LRP1B LDLR	8.44e-07	21	31	3	21337463
Pubmed	ERp57 is essential for efficient folding of glycoproteins sharing common structural domains.	LAMB1 AGRN LDLR	1.46e-06	25	31	3	17170699
Pubmed	Secretory carcinoma of breast: pattern of MUC 2/MUC 4/MUC 6 expression.	MUC2 MUC4	2.31e-06	3	31	2	23305535
Pubmed	Notch receptor expression in human brain arteriovenous malformations.	NOTCH1 NOTCH4	2.31e-06	3	31	2	25846406
Pubmed	Acid sphingomyelinase promotes lipoprotein retention within early atheromata and accelerates lesion progression.	SMPD1 LDLR	2.31e-06	3	31	2	18669882
Pubmed	Diagnosis of pancreatic neoplasms using a novel method of DNA methylation analysis of mucin expression in pancreatic juice.	MUC2 MUC4	2.31e-06	3	31	2	24714692
Pubmed	Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches.	NOTCH1 NOTCH4	2.31e-06	3	31	2	18593923
Pubmed	Characterization of Notch Signalling Pathway Members in Normal Prostate, Prostatic Intraepithelial Neoplasia (PIN) and Prostatic Adenocarcinoma.	NOTCH1 NOTCH4	2.31e-06	3	31	2	26341090
Pubmed	MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters.	LRP4 AGRN	2.31e-06	3	31	2	24244707
Pubmed	Differential expression of Notch genes in human osteoblastic cells.	NOTCH1 NOTCH4	2.31e-06	3	31	2	11836628
Pubmed	Agrin binds to the N-terminal region of Lrp4 protein and stimulates association between Lrp4 and the first immunoglobulin-like domain in muscle-specific kinase (MuSK).	LRP4 AGRN	2.31e-06	3	31	2	21969364
Pubmed	Isolation of a novel latent transforming growth factor-beta binding protein gene (LTBP-3).	LTBP1 LTBP3	2.31e-06	3	31	2	7730318
Pubmed	Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation.	NOTCH1 NOTCH4	2.31e-06	3	31	2	14988227
Pubmed	Two atypical enteropathogenic Escherichia coli strains induce the production of secreted and membrane-bound mucins to benefit their own growth at the apical surface of human mucin-secreting intestinal HT29-MTX cells.	MUC2 MUC4	2.31e-06	3	31	2	20065027
Pubmed	Delta-like 4/Notch pathway is differentially regulated in benign and malignant thyroid tissues.	NOTCH1 NOTCH4	2.31e-06	3	31	2	22066479
Pubmed	Unique patterns of Notch1, Notch4 and Jagged1 expression in ovarian vessels during folliculogenesis and corpus luteum formation.	NOTCH1 NOTCH4	2.31e-06	3	31	2	15939383
Pubmed	Endothelial Notch signaling is upregulated in human brain arteriovenous malformations and a mouse model of the disease.	NOTCH1 NOTCH4	2.31e-06	3	31	2	19546852
Pubmed	NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications.	NOTCH1 NOTCH4	2.31e-06	3	31	2	21679465
Pubmed	Notch signaling: cell fate control and signal integration in development.	NOTCH1 NOTCH4	2.31e-06	3	31	2	10221902
Pubmed	Clinicopathological and prognostic significance of MUC-2, MUC-4 and MUC-5AC expression in japanese gastric carcinomas.	MUC2 MUC4	2.31e-06	3	31	2	23464473
Pubmed	Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.	NOTCH1 NOTCH4	2.31e-06	3	31	2	28871079
Pubmed	Latent TGF-beta binding proteins (LTBPs)-1 and -3 coordinate proliferation and osteogenic differentiation of human mesenchymal stem cells.	LTBP1 LTBP3	2.31e-06	3	31	2	18672106
Pubmed	Notch1 is pan-endothelial at the onset of flow and regulated by flow.	NOTCH1 NOTCH4	2.31e-06	3	31	2	25830332
Pubmed	Latent transforming growth factor-beta binding proteins (LTBPs)--structural extracellular matrix proteins for targeting TGF-beta action.	LTBP1 LTBP3	2.31e-06	3	31	2	10743502
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	LAMB1 LTBP1 AGRN LDLR SPON2	2.59e-06	248	31	5	24006456
Pubmed	Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.	NOTCH1 NOTCH4	4.61e-06	4	31	2	28061457
Pubmed	The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.	NOTCH1 NOTCH4	4.61e-06	4	31	2	24145721
Pubmed	A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.	NOTCH1 NOTCH4	4.61e-06	4	31	2	20069356
Pubmed	ADAM10-Dependent Signaling Through Notch1 and Notch4 Controls Development of Organ-Specific Vascular Beds.	NOTCH1 NOTCH4	4.61e-06	4	31	2	27354212
Pubmed	Expression and clinical significance of Notch receptors in human renal cell carcinoma.	NOTCH1 NOTCH4	4.61e-06	4	31	2	19404845
Pubmed	Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.	NOTCH1 NOTCH4	4.61e-06	4	31	2	28669409
Pubmed	Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.	LTBP1 LTBP3	4.61e-06	4	31	2	15611103
Pubmed	Evolutionary analysis of vertebrate Notch genes.	NOTCH1 NOTCH4	4.61e-06	4	31	2	11466531
Pubmed	Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.	NOTCH1 NOTCH4	4.61e-06	4	31	2	24151014
Pubmed	Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin.	NOTCH1 NOTCH4	4.61e-06	4	31	2	17984306
Pubmed	Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.	NOTCH1 NOTCH4	4.61e-06	4	31	2	11401408
Pubmed	The collagen ColQ binds to LRP4 and regulates the activation of the Muscle-Specific Kinase-LRP4 receptor complex by agrin at the neuromuscular junction.	LRP4 AGRN	4.61e-06	4	31	2	37356721
Pubmed	Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.	NOTCH1 NOTCH4	4.61e-06	4	31	2	10194420
Pubmed	Functional conservation of mouse Notch receptor family members.	NOTCH1 NOTCH4	4.61e-06	4	31	2	8898100
Pubmed	Notch1 and Notch4 core binding domain peptibodies exhibit distinct ligand-binding and anti-angiogenic properties.	NOTCH1 NOTCH4	4.61e-06	4	31	2	36376768
Pubmed	Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.	NOTCH1 NOTCH4	4.61e-06	4	31	2	11459941
Pubmed	Notch1 deficiency results in decreased inflammation during wound healing and regulates vascular endothelial growth factor receptor-1 and inflammatory cytokine expression in macrophages.	NOTCH1 NOTCH4	4.61e-06	4	31	2	20739676
Pubmed	Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.	NOTCH1 NOTCH4	4.61e-06	4	31	2	18184405
Pubmed	Mucin expression pattern in pancreatic diseases: findings from EUS-guided fine-needle aspiration biopsies.	MUC2 MUC4	4.61e-06	4	31	2	21647207
Pubmed	Butyrate enemas upregulate Muc genes expression but decrease adherent mucus thickness in mice colon.	MUC2 MUC4	4.61e-06	4	31	2	18198997
Pubmed	Extracellular fibrillar structure of latent TGF beta binding protein-1: role in TGF beta-dependent endothelial-mesenchymal transformation during endocardial cushion tissue formation in mouse embryonic heart.	LTBP1 LTBP3	4.61e-06	4	31	2	9008713
Pubmed	The latent transforming growth factor beta binding protein (LTBP) family.	LTBP1 LTBP3	4.61e-06	4	31	2	11104663
Pubmed	Expression of NOTCH1, NOTCH4, HLA-DMA and HLA-DRA is synergistically associated with T cell exclusion, immune checkpoint blockade efficacy and recurrence risk in ER-negative breast cancer.	NOTCH1 NOTCH4	4.61e-06	4	31	2	35543859
Pubmed	Notch signaling in the mammalian central nervous system: insights from mouse mutants.	NOTCH1 NOTCH4	4.61e-06	4	31	2	15917835
Pubmed	Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.	NOTCH1 NOTCH4	4.61e-06	4	31	2	23444212
Pubmed	Deregulated expression of Notch receptors in human hepatocellular carcinoma.	NOTCH1 NOTCH4	4.61e-06	4	31	2	17920003
Pubmed	Sequential deposition of latent TGF-beta binding proteins (LTBPs) during formation of the extracellular matrix in human lung fibroblasts.	LTBP1 LTBP3	4.61e-06	4	31	2	16157329
Pubmed	Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.	MUC2 NOTCH1 NOTCH4	6.68e-06	41	31	3	22675208
Pubmed	Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo.	LRP4 LRP1B	7.68e-06	5	31	2	20383322
Pubmed	Polymorphism of human mucin genes in chest disease: possible significance of MUC2.	MUC2 MUC4	7.68e-06	5	31	2	11062147
Pubmed	Assessment of the association between genetic polymorphisms in transforming growth factor beta, and its binding protein (LTBP), and the presence, and expansion, of Abdominal Aortic Aneurysm.	LTBP1 LTBP3	7.68e-06	5	31	2	19897194
Pubmed	Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease.	MUC2 MUC4	7.68e-06	5	31	2	17058067
Pubmed	Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.	NOTCH1 NOTCH4	7.68e-06	5	31	2	21124806
Pubmed	Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice.	LRP4 AGRN	7.68e-06	5	31	2	31268420
Pubmed	Multifaceted transcriptional regulation of the murine intestinal mucus layer by endogenous microbiota.	MUC2 MUC4	7.68e-06	5	31	2	18035521
Pubmed	Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).	NOTCH1 NOTCH4	7.68e-06	5	31	2	23675950
Pubmed	MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.	NOTCH1 NOTCH4	7.68e-06	5	31	2	11101851
Pubmed	Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.	NOTCH1 NOTCH4	7.68e-06	5	31	2	15882997
Pubmed	Nrf2 Transcriptional Activity Governs Intestine Development.	MUC2 NOTCH1	7.68e-06	5	31	2	35682851
Pubmed	Association of Notch pathway down-regulation with Triple Negative/Basal-like breast carcinomas and high tumor-infiltrating FOXP3+ Tregs.	NOTCH1 NOTCH4	7.68e-06	5	31	2	27118257
Pubmed	MUC1, MUC2, MUC4, MUC5AC and MUC6 expression in the progression of prostate cancer.	MUC2 MUC4	7.68e-06	5	31	2	16475027
Pubmed	Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.	NOTCH1 NOTCH4	7.68e-06	5	31	2	20554499
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	LAMB1 LTBP1 LTBP3 AGRN	8.59e-06	146	31	4	27068509
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	PRMT2 LTBP1 LTBP3 MDFI AGRN NOTCH1	8.87e-06	560	31	6	21653829
Pubmed	RBP-L, a transcription factor related to RBP-Jkappa.	NOTCH1 NOTCH4	1.15e-05	6	31	2	9111338
Pubmed	Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.	NOTCH1 NOTCH4	1.15e-05	6	31	2	20870902
Pubmed	A study on Notch signaling in human breast cancer.	NOTCH1 NOTCH4	1.15e-05	6	31	2	17822320
Pubmed	Characterization of Notch receptor expression in the developing mammalian heart and liver.	NOTCH1 NOTCH4	1.15e-05	6	31	2	12244553
Pubmed	Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site.	NOTCH1 NOTCH4	1.15e-05	6	31	2	18239137
Pubmed	Notch4 Negatively Regulates the Inflammatory Response to Mycobacterium tuberculosis Infection by Inhibiting TAK1 Activation.	NOTCH1 NOTCH4	1.15e-05	6	31	2	29228365
Pubmed	Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.	NOTCH1 NOTCH4	1.15e-05	6	31	2	19503073
Pubmed	Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3.	NOTCH1 NOTCH4	1.15e-05	6	31	2	7835890
Pubmed	Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development.	LAMB1 NOTCH4	1.15e-05	6	31	2	10444590
Pubmed	Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.	NOTCH1 NOTCH4	1.15e-05	6	31	2	18299578
Pubmed	Notch4 reveals a novel mechanism regulating Notch signal transduction.	NOTCH1 NOTCH4	1.15e-05	6	31	2	24667410
Interaction	NTN5 interactions	LRP4 LTBP1 LRP1B LDLR NOTCH1	2.56e-10	24	31	5	int:NTN5
Interaction	IGFL3 interactions	LRP4 LAMB1 LRP1B AGRN LDLR NOTCH1	1.48e-09	75	31	6	int:IGFL3
Interaction	ZFP41 interactions	LRP4 LTBP1 LRP1B AGRN LDLR	2.43e-08	57	31	5	int:ZFP41
Interaction	FOXD4L6 interactions	MDFI LRP1B LDLR NOTCH1	9.25e-07	49	31	4	int:FOXD4L6
Interaction	CACNA1A interactions	LAMB1 LTBP1 LTBP3 AGRN NOTCH1	1.17e-06	123	31	5	int:CACNA1A
Interaction	IGSF5 interactions	LRP4 LDLR NOTCH1	1.19e-06	14	31	3	int:IGSF5
Interaction	DEFB123 interactions	LRP4 LRP1B LDLR	1.82e-06	16	31	3	int:DEFB123
Interaction	ZNF408 interactions	LRP4 LTBP1 MDFI LRP1B LDLR	2.63e-06	145	31	5	int:ZNF408
Interaction	FEZF1 interactions	LRP4 MDFI LRP1B	1.05e-05	28	31	3	int:FEZF1
Interaction	HOXA1 interactions	SPRY3 LTBP1 LTBP3 MDFI AGRN NOTCH1	1.48e-05	356	31	6	int:HOXA1
Interaction	OS9 interactions	LAMB1 CASR SMPD1 LRP1B AGRN	1.95e-05	219	31	5	int:OS9
Interaction	WNT10A interactions	LTBP3 LDLR NOTCH1	2.47e-05	37	31	3	int:WNT10A
Interaction	NOTCH3 interactions	CASR LTBP1 NOTCH1 NOTCH4	2.62e-05	113	31	4	int:NOTCH3
Interaction	DLL4 interactions	NOTCH1 NOTCH4	3.42e-05	6	31	2	int:DLL4
Interaction	CFC1 interactions	LAMB1 SPINT1 AGRN NOTCH1	4.02e-05	126	31	4	int:CFC1
Interaction	EXT1 interactions	ERGIC3 LDLR NOTCH1	9.12e-05	57	31	3	int:EXT1
Interaction	ZNF563 interactions	LRP4 LRP1B	1.50e-04	12	31	2	int:ZNF563
Interaction	MBD1 interactions	LTBP3 MDFI NOTCH1	2.23e-04	77	31	3	int:MBD1
Interaction	ZNF707 interactions	LRP4 MDFI NOTCH1	2.41e-04	79	31	3	int:ZNF707
Interaction	MAML2 interactions	NOTCH1 NOTCH4	3.07e-04	17	31	2	int:MAML2
Interaction	PSEN2 interactions	ERGIC3 NOTCH1 NOTCH4	3.09e-04	86	31	3	int:PSEN2
Interaction	OLFM3 interactions	LRP1B AGRN	3.45e-04	18	31	2	int:OLFM3
Interaction	ELSPBP1 interactions	SPINT1 AGRN NOTCH1	3.77e-04	92	31	3	int:ELSPBP1
Interaction	FBXO2 interactions	LAMB1 SPINT1 LRP1B AGRN NOTCH1	3.78e-04	411	31	5	int:FBXO2
Interaction	CCN6 interactions	LDLR NOTCH1	3.85e-04	19	31	2	int:CCN6
Interaction	MAML3 interactions	NOTCH1 NOTCH4	4.28e-04	20	31	2	int:MAML3
Interaction	ZNF224 interactions	LRP4 LRP1B	4.28e-04	20	31	2	int:ZNF224
Interaction	NOTCH2 interactions	FBXL17 CASR LTBP1 NOTCH1 NOTCH4	4.31e-04	423	31	5	int:NOTCH2
Interaction	TMEM126A interactions	FBXL17 LAMB1 SMPD1	4.54e-04	98	31	3	int:TMEM126A
Interaction	EGFL6 interactions	LRP1B LDLR	4.72e-04	21	31	2	int:EGFL6
Interaction	CASR interactions	CASR NOTCH1	5.19e-04	22	31	2	int:CASR
Interaction	EDN3 interactions	AGRN LDLR NOTCH1	6.03e-04	108	31	3	int:EDN3
Interaction	GOLGA8G interactions	LRP4 LDLR	6.19e-04	24	31	2	int:GOLGA8G
Interaction	DNAJC10 interactions	LAMB1 LTBP3 LRP1B LDLR	6.48e-04	260	31	4	int:DNAJC10
Interaction	PCDHGA7 interactions	SLITRK3 LTBP1	6.72e-04	25	31	2	int:PCDHGA7
Interaction	FBXO6 interactions	LAMB1 LTBP1 LTBP3 ERGIC3 AGRN LDLR	6.83e-04	717	31	6	int:FBXO6
Cytoband	4p16.3	PDE6B SPON2	1.52e-03	85	31	2	4p16.3
GeneFamily	Low density lipoprotein receptors	LRP4 LRP1B LDLR	3.29e-07	13	20	3	634
GeneFamily	Latent transforming growth factor beta binding proteins	LTBP1 LTBP3	6.97e-06	4	20	2	628
GeneFamily	CD molecules\|Mucins	MUC2 MUC4	2.41e-04	21	20	2	648
GeneFamily	Ankyrin repeat domain containing	NOTCH1 NOTCH4	2.89e-02	242	20	2	403
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMB1 LTBP1 LTBP3 VWA7 AGRN SPON2 FBN3 OTOG	5.77e-11	196	31	8	M3008
Coexpression	NABA_CORE_MATRISOME	LAMB1 LTBP1 LTBP3 VWA7 AGRN SPON2 FBN3 OTOG	8.49e-10	275	31	8	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMB1 LTBP1 LTBP3 VWA7 AGRN SPON2 OTOG	2.22e-09	191	31	7	MM17059
Coexpression	NABA_CORE_MATRISOME	LAMB1 LTBP1 LTBP3 VWA7 AGRN SPON2 OTOG	2.42e-08	270	31	7	MM17057
Coexpression	NABA_MATRISOME	LAMB1 LTBP1 LTBP3 VWA7 MUC2 MUC4 AGRN SPON2 FBN3 OTOG	1.69e-07	1026	31	10	M5889
Coexpression	NABA_MATRISOME	LAMB1 LTBP1 LTBP3 VWA7 MUC2 MUC4 AGRN SPON2 OTOG	1.67e-06	1008	31	9	MM17056
Coexpression	LAKE_ADULT_KIDNEY_C13_THICK_ASCENDING_LIMB	FBXL17 LAMB1 CASR LRP1B	1.69e-05	131	31	4	M39232
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	LAMB1 SMPD1 LTBP1 LTBP3 TNFRSF10A LDLR	1.51e-04	703	31	6	MM1055
Coexpression	FUKUSHIMA_TNFSF11_TARGETS	NOTCH1 NOTCH4	1.61e-04	16	31	2	M2207
Coexpression	FUKUSHIMA_TNFSF11_TARGETS	NOTCH1 NOTCH4	1.61e-04	16	31	2	MM1296
Coexpression	LAKE_ADULT_KIDNEY_C17_COLLECTING_SYSTEM_PCS_STRESSED_DISSOC_SUBSET	FBXL17 LAMB1 LRP1B LDLR	1.78e-04	240	31	4	M39236
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500	LRP4 LAMB1 LTBP1 SPINT1 AGRN NOTCH1	1.69e-05	398	30	6	gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlas	kidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_500	LRP4 LAMB1 LTBP1 NOTCH1	5.39e-05	148	30	4	gudmap_kidney_P3_CapMes_Crym_k2_500
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_500	LRP4 LAMB1 AGRN NOTCH1	8.23e-05	165	30	4	gudmap_kidney_P4_CapMesRenVes_Crym_k3_500
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	LAMB1 PRMT2 SMPD1 LTBP1 MDFI C9 PDE6B AGRN FBN3	1.32e-04	1466	30	9	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP4 LAMB1 LTBP1 NRXN2 SPON2	1.93e-07	189	31	5	324c81285c51f4f8bb1aef428b18fe2c549c2c11
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP4 LAMB1 LTBP1 NRXN2 SPON2	2.03e-07	191	31	5	5c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP4 LAMB1 LTBP1 NRXN2 SPON2	2.03e-07	191	31	5	80484d39f34703a33b9bac09826b7a526e883cab
ToppCell	facs-Heart-LV-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB1 LTBP3 NRXN2 SPON2	5.58e-06	169	31	4	849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCell	356C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 SLITRK3 LTBP1 MDFI	6.13e-06	173	31	4	75e26a65071b0d2f30ed0b2aa9859c488f5cf362
ToppCell	356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 SLITRK3 LTBP1 MDFI	6.13e-06	173	31	4	26e2e674f5d312fa8f61c11b553dc6101f063b16
ToppCell	facs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB1 LTBP3 NRXN2 SPON2	6.56e-06	176	31	4	f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 LTBP1 NRXN2 LRP1B	6.56e-06	176	31	4	2e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 LTBP1 NRXN2 LRP1B	6.56e-06	176	31	4	f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell	facs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB1 LTBP3 NRXN2 SPON2	6.56e-06	176	31	4	fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 LTBP1 MDFI NRXN2	6.70e-06	177	31	4	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 LTBP1 MDFI NRXN2	6.70e-06	177	31	4	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP1 MDFI SPON2 ATP8A2	7.16e-06	180	31	4	79c5725f02e038d0187f4a1e1591f2492538aa57
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LAMB1 LTBP1 MDFI SPON2	7.32e-06	181	31	4	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRP4 LTBP1 MDFI SPON2	7.65e-06	183	31	4	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP3 VWA7 SPON2 ATP8A2	8.69e-06	189	31	4	d00410010283dc6191ce9857d6c7952678fed588
ToppCell	droplet-Lung-immune-endo-depleted\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP4 LAMB1 LTBP3 SPON2	8.69e-06	189	31	4	c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCell	droplet-Lung-immune-endo-depleted-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP4 LAMB1 LTBP3 SPON2	8.69e-06	189	31	4	2a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCell	droplet-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP4 LAMB1 LTBP3 SPON2	8.69e-06	189	31	4	5a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP4 LTBP1 NRXN2 SPON2	8.87e-06	190	31	4	00fd993675faf53adf985b9316a18c8a33242029
ToppCell	IPF-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	LRP4 MDFI NOTCH1 NOTCH4	8.87e-06	190	31	4	4f15842b424eefadbfe451875e517cf70e29607f
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP4 LAMB1 LTBP3 SPON2	8.87e-06	190	31	4	9cd147a174017ebda23cc47b6d4552d898acd092
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP4 LTBP1 NRXN2 SPON2	8.87e-06	190	31	4	8cda09d761c6b504a744959d587c183f94f1beeb
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP4 LAMB1 LTBP1 SPON2	9.05e-06	191	31	4	094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP4 LTBP1 NRXN2 SPON2	9.05e-06	191	31	4	beb5bb42bd53bce01339da9110d374901548793c
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP4 LTBP1 NRXN2 SPON2	9.05e-06	191	31	4	6609d85fd2577633dcc067507304a6f9e5865ca3
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP4 LAMB1 LTBP1 SPON2	9.05e-06	191	31	4	997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCell	facs-Lung-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP4 LAMB1 LTBP1 SPON2	9.05e-06	191	31	4	ba02cbdfda6a94374a6472eb88499059979af472
ToppCell	droplet-Lung-nan-18m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP4 LAMB1 LTBP1 SPON2	9.24e-06	192	31	4	c09966f4d63a739a56db4df7e0e0ee9ecacd21ad
ToppCell	droplet-Lung-1m-Mesenchymal\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMB1 LTBP1 LTBP3 SPON2	9.24e-06	192	31	4	01433bd4794b8bcc51fe4249124a0f4289b9d6e2
ToppCell	facs-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP4 LAMB1 LTBP1 SPON2	9.24e-06	192	31	4	8df15085b35b86f39debd933284cb703c5dd63c2
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP4 LAMB1 LTBP1 SPON2	9.24e-06	192	31	4	d22c1135867bcb9076435e2c6eb1cc1248990d0c
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB1 LTBP1 LTBP3 SPON2	9.43e-06	193	31	4	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP4 LAMB1 LTBP1 NRXN2	1.00e-05	196	31	4	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP4 LAMB1 LTBP1 NRXN2	1.00e-05	196	31	4	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	droplet-Mammary_Gland-nan-3m-Epithelial-luminal_progenitor_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDFI SPINT1 MUC4 LDLR	1.00e-05	196	31	4	22fcfb713f402ebbd43b2822f0fd919cdbfba6e4
ToppCell	368C-Fibroblasts-Fibroblast-G-\|368C / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 MDFI SPON2 ATP8A2	1.02e-05	197	31	4	d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCell	368C-Fibroblasts-Fibroblast-G\|368C / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 MDFI SPON2 ATP8A2	1.02e-05	197	31	4	156155c2f0c1a2461e45803da578af18ee221660
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG-25\|World / Primary Cells by Cluster	LRP4 LTBP1 LDLR NOTCH1	1.02e-05	197	31	4	9d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRP4 LAMB1 LTBP1 ATP8A2	1.02e-05	197	31	4	ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG\|World / Primary Cells by Cluster	LRP4 LTBP1 LDLR NOTCH1	1.02e-05	197	31	4	61749ccafeb938c310cff1de5ff924a1c794325a
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRP4 LAMB1 MUC4 ATP8A2	1.02e-05	197	31	4	1da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMB1 SMPD1 SLITRK3 LTBP1	1.02e-05	197	31	4	6806ec223e542f0475303698eb78c1cc527f5c6b
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 LTBP1 MDFI ATP8A2	1.04e-05	198	31	4	a9afedbc0556faf4a46f7bf28f4a9adb3bc859d8
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 LTBP1 MDFI ATP8A2	1.04e-05	198	31	4	7b5350768f306ec528e271d2ac4470bf668ec6f0
ToppCell	facs-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB1 LTBP1 LTBP3 SPON2	1.04e-05	198	31	4	0dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 LTBP1 MDFI SPON2	1.09e-05	200	31	4	731e55070a7ff315091855bd88cda30e5a7e1a98
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SLITRK3 LTBP1 NRXN2 SPON2	1.09e-05	200	31	4	0b2614b8513693dd508c9003699049efd9abac52
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 LTBP1 MDFI SPON2	1.09e-05	200	31	4	082e718c1da3f4fdd33a001d15ad3ddb2be985c7
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	LRP4 LAMB1 LTBP1 LTBP3	1.09e-05	200	31	4	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	Biopsy_IPF-Epithelial-Basal\|Biopsy_IPF / Sample group, Lineage and Cell type	LRP4 MDFI SPINT1 NOTCH1	1.09e-05	200	31	4	5cea84581201cee7ba8141b96e65864f4fd67113
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-2,_SCARA5\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SLITRK3 LTBP1 NRXN2 SPON2	1.09e-05	200	31	4	c338a08c1605527ab9aaf62ea151a19e8469dc6d
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	LRP4 LAMB1 LTBP1 LTBP3	1.09e-05	200	31	4	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SLITRK3 LTBP1 NRXN2 SPON2	1.09e-05	200	31	4	8d2ceb2080c67b20f452eeca605aa27a58033c04
ToppCell	Bronchial_Biopsy-Mesenchymal-Fibroblasts\|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X	LAMB1 LTBP1 SPON2	9.76e-05	129	31	3	13cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCell	E17.5-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LRP4 SMPD1 SPINT1	1.52e-04	150	31	3	201d5b68e71c6c003285428be96c488e6d526edf
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SPINT1 MUC4 LRP1B	1.59e-04	152	31	3	1b2a39ae159e79f1fb18d6d164bd7acab5299fca
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP1 MUC4 LDLR	1.62e-04	153	31	3	0ef7c45cdd854c79e527006034029767f8e108b2
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-3\|TCGA-Adrenal / Sample_Type by Project: Shred V9	MDFI NOTCH1 NOTCH4	1.88e-04	161	31	3	52239a887799362256ecd7e740b716b88ed59a62
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LTBP1 TMEM215 C9	1.95e-04	163	31	3	e526104a3a574ee860078ce7c049e7fec9443f37
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 NRXN2 SPON2	1.95e-04	163	31	3	6c4d4c55fc8a731acca13c1ba7287f238a9d81e0
ToppCell	facs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP3 VWA7 SPON2	2.09e-04	167	31	3	78909f685ccd1321064eb0887caf9263e0e54879
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP4 TMEM215 SPON2	2.13e-04	168	31	3	d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCell	Endothelial-Endothelial-G\|Endothelial / shred on cell class and cell subclass (v4)	LAMB1 NRXN2 ATP8A2	2.28e-04	172	31	3	644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell	Adult-Endothelial-endothelial_cell_of_bronchial_vessel\|Adult / Lineage, Cell type, age group and donor	TNFRSF10A LRP1B NOTCH4	2.28e-04	172	31	3	ad4ffdb3fc0c560a9cbaa2bc048476cbc43e8fd6
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRP4 LAMB1 SPON2	2.32e-04	173	31	3	cbd65dd5b01cc959e3ccbc89330ddd0122296ea3
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRP4 LAMB1 SPON2	2.32e-04	173	31	3	f9d6e892d66f9b94e4d5beb9f5dec9b606bc868a
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDFI LDLR NOTCH1	2.32e-04	173	31	3	5d7c53c6d1cdd385e44b79b82faec901747d1736
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDFI LDLR NOTCH1	2.36e-04	174	31	3	b2fc2a756f8e373ad903bd416d9de703d945fa1c
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	AGRN NOTCH1 NOTCH4	2.36e-04	174	31	3	b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDFI LDLR NOTCH1	2.36e-04	174	31	3	9eab43885496b8586f8ec5b4bcb1fd5b209218e5
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDFI LDLR NOTCH1	2.36e-04	174	31	3	a9f34d1237f335d27c5560ff514368f4709f9144
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDFI LDLR NOTCH1	2.36e-04	174	31	3	0fccd90ef72ec2e5eb369fe6d6d126c60886485a
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CASR MDFI ATP8A2	2.40e-04	175	31	3	f1394aacc8a94ca555dd19aaed5a18da99c6bf40
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CASR MDFI ATP8A2	2.40e-04	175	31	3	7bf1194d93fbe2dbf9d953e0a32b2a6d88251ed1
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	LAMB1 CASR LRP1B	2.44e-04	176	31	3	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBXL17 LTBP1 TMEM215	2.48e-04	177	31	3	4553ee8cd9c24db6511b09fe49ed11a89e7cde9e
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)\|343B / Donor, Lineage, Cell class and subclass (all cells)	LTBP1 MDFI NRXN2	2.48e-04	177	31	3	e55d21d4d61a069b9bbe0e7595fbfb7cfbacfd87
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	LTBP1 MDFI NRXN2	2.48e-04	177	31	3	43ba6f12c2fb32698a420bf799d46ac1b558f146
ToppCell	Adult-Endothelial-endothelial_cell_of_bronchial_vessel-D175\|Adult / Lineage, Cell type, age group and donor	TNFRSF10A LRP1B NOTCH4	2.48e-04	177	31	3	c9f269765c7d5d29caab75910e51645606ed562e
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1-Excitatory_Neuron.Slc17a7.Parm1.Cadm2_(Deep_layer_pyramidal_cells--layer_5)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	VWA7 MUC2	2.54e-04	34	31	2	c217c09c1d7e84f14b9e0d1e7c6e8e916b3c7d10
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRP4 MDFI SPON2	2.56e-04	179	31	3	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-BEST2+_Goblet_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC2 MUC4 LDLR	2.56e-04	179	31	3	c833ded1f9e87be2ba2037820d92a389560b711c
ToppCell	droplet-Liver-LIVER-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP1 TMEM215 PDE6B	2.61e-04	180	31	3	47e345359064dc8ceec982b062e47802e728b43f
ToppCell	droplet-Liver-LIVER-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP1 TMEM215 PDE6B	2.61e-04	180	31	3	3d95232b5785c705f41e01e3ffe0fa8dce1ff0a7
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMB1 LTBP1 MDFI	2.61e-04	180	31	3	01f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRP4 LAMB1 LTBP1	2.65e-04	181	31	3	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-proliferating_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	LAMB1 AGRN NOTCH4	2.69e-04	182	31	3	997d37ca2af661c92a56add888762724dfccc890
ToppCell	Basal\|World / shred by cell class for mouse tongue	LAMB1 LTBP1 AGRN	2.74e-04	183	31	3	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDFI AGRN ATP8A2	2.74e-04	183	31	3	6c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCell	droplet-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP3 TMEM215 SPON2	2.74e-04	183	31	3	ddc45fb591ba0ce3fa05c08051d58286a89ef835
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP3 TMEM215 SPON2	2.74e-04	183	31	3	a253ad65673fce6cb453e709cb235ce7cbfa18b7
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|normal_Lung / Location, Cell class and cell subclass	LTBP1 TMEM215 MDFI	2.78e-04	184	31	3	0b336489c10e8c3c957795dd845454f03404382b
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	SPINT1 AGRN FBN3	2.78e-04	184	31	3	bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|343B / Donor, Lineage, Cell class and subclass (all cells)	SPINT1 AGRN FBN3	2.78e-04	184	31	3	cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LAMB1 LTBP1 MDFI	2.82e-04	185	31	3	87c416d14ca6255bee39b16e7571553e36ee3069
ToppCell	droplet-Marrow-nan-18m-Hematologic-hematopoietic_precursor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LTBP1 LTBP3 MDFI	2.82e-04	185	31	3	de353368f4f6a7a0a66e391d586879876fbe2734
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRMT2 SLITRK3 NRXN2	2.87e-04	186	31	3	2f103ce2427f9cf2c1fafb6bd6045c5863a47549
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB1 LRP1B LDLR	2.87e-04	186	31	3	d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCell	Control-Endothelial-Endothelial-Artery\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LTBP1 TNFRSF10A LRP1B	2.87e-04	186	31	3	2d3a975d2bf92e18e3410dd413fc9f84831d82de
Drug	ametryn	CASR SMPD1 ATP8A2	1.53e-06	17	31	3	CID000013263
Drug	prometryn	CASR SMPD1 ATP8A2	1.84e-06	18	31	3	CID000004929
Drug	swep	CASR ATP8A2	5.38e-06	3	31	2	CID000015969
Drug	monatepil	LRP4 LRP1B LDLR	8.15e-06	29	31	3	CID000060810
Drug	PSA11-SPM	SMPD1 LDLR	3.75e-05	7	31	2	CID006439362
Drug	funiferine N-oxide	LTBP1 LTBP3 AGRN	4.04e-05	49	31	3	CID000191631
Drug	ezetimibe	LRP4 SMPD1 LRP1B LDLR	4.58e-05	147	31	4	CID000150311
Drug	Verteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A	LAMB1 LTBP1 AGRN LDLR	5.63e-05	155	31	4	6817_DN
Drug	25-hydroxycholesterol	LRP4 SMPD1 LRP1B LDLR	6.37e-05	160	31	4	CID000065094
Drug	probucol	LRP4 SMPD1 LRP1B LDLR	6.69e-05	162	31	4	CID000004912
Drug	chlorpyrifos-methyl	SMPD1 ATP8A2	8.02e-05	10	31	2	CID000021803
Disease	level of spondin-2 in blood serum	PDE6B SPON2	3.20e-06	3	31	2	OBA_2043641
Disease	mucositis (biomarker_via_orthology)	MUC2 MUC4	1.07e-05	5	31	2	DOID:0080178 (biomarker_via_orthology)
Disease	mucinous adenocarcinoma (is_marker_for)	MUC2 MUC4	1.07e-05	5	31	2	DOID:3030 (is_marker_for)
Disease	hemangiopericytoma (is_marker_for)	NOTCH1 NOTCH4	3.83e-05	9	31	2	DOID:264 (is_marker_for)
Disease	cholangiocarcinoma (is_marker_for)	MUC2 MUC4 NOTCH1	4.19e-05	64	31	3	DOID:4947 (is_marker_for)
Disease	allergic conjunctivitis (is_marker_for)	MUC2 MUC4	4.78e-05	10	31	2	DOID:11204 (is_marker_for)
Disease	Myasthenic Syndromes, Congenital, Slow Channel	LRP4 AGRN	1.27e-04	16	31	2	C0751885
Disease	Congenital Myasthenic Syndromes, Postsynaptic	LRP4 AGRN	1.44e-04	17	31	2	C0751883
Disease	Congenital Myasthenic Syndromes, Presynaptic	LRP4 AGRN	1.81e-04	19	31	2	C0751884
Disease	Myasthenic Syndromes, Congenital	LRP4 AGRN	2.91e-04	24	31	2	C0751882
Disease	lateral orbital frontal cortex volume measurement	FBXL17 OTOG	2.91e-04	24	31	2	EFO_0010312
Disease	Carcinoma, Pancreatic Ductal	NOTCH1 NOTCH4	2.91e-04	24	31	2	C0887833
Disease	ulcerative colitis	FBXL17 LAMB1 NOTCH1 NOTCH4	4.03e-04	335	31	4	EFO_0000729
Disease	Age related macular degeneration	TNFRSF10A C9	4.56e-04	30	31	2	C0242383
Disease	Takayasu arteritis	VWA7 LRP1B NOTCH4	5.01e-04	148	31	3	EFO_1001857
Disease	glaucoma	LTBP1 LTBP3 LRP1B	5.63e-04	154	31	3	MONDO_0005041
Disease	worry measurement	FBXL17 VWA7 NOTCH4	5.63e-04	154	31	3	EFO_0009589
Disease	liver cirrhosis (biomarker_via_orthology)	SPINT1 MUC2	5.87e-04	34	31	2	DOID:5082 (biomarker_via_orthology)
Disease	endometrial cancer (is_marker_for)	NOTCH1 NOTCH4	6.22e-04	35	31	2	DOID:1380 (is_marker_for)
Disease	colon cancer (biomarker_via_orthology)	TNFRSF10A MUC2	7.73e-04	39	31	2	DOID:219 (biomarker_via_orthology)
Disease	asthma	CASR VWA7 MUC2 LRP1B NOTCH4	1.03e-03	751	31	5	MONDO_0004979

Protein segments in the cluster

Peptide	Gene	Start	Entry
DCPRSESQGEEPAEC	PRMT2	6	P55345
LEGTDPDCADPLCCR	SMPD1	216	P17405
EGEPTCCFECVECPD	CASR	556	P41180
PCSCDPQGAVRDDCE	AGRN	846	O00468
CEDIDECSLSDGLCP	FBN3	1111	Q75N90
CEDVDECGSRESPCQ	FBN3	1761	Q75N90
CRMPPPCSDSCDFDD	ATP8A2	466	Q9NTI2
CEGSEDACEEPCFPS	MUC4	5071	Q99102
THCEVDIDECDPDPC	NOTCH1	561	P46531
PDCPDDSDESLDTCP	LRP1B	56	Q9NZR2
CEDIDECLNPSTCPD	LTBP1	996	Q14766
CEDPEEEVAPASCSE	MUC2	206	Q02817
CEDGCPPDCDSLRDL	PDE6B	36	P35913
VFDPDSLDPDRCESC	ERGIC3	131	Q9Y282
PCQAERDDSDCEEPI	NRXN2	1476	Q9P2S2
ACDCDPRGIETPQCD	LAMB1	1131	P07942
GDADCRESPENPCDC	FBXL17	296	Q9UF56
SGECADCDLPCDLDC	MDFI	206	Q99750
CEDIDECRDPSSCPD	LTBP3	701	Q9NS15
RQCVPTEPCEDAEDD	C9	86	P02748
PSYSCECDPDLCEAE	OTOG	2536	Q6ZRI0
ECDPDLCEAELVPSC	OTOG	2541	Q6ZRI0
CPELEEEAECVPDNC	SPON2	316	Q9BUD6
DSEEIDEPCFDPCYC	SLITRK3	36	O94933
TRCEEDIDECRSSPC	NOTCH4	546	Q99466
DDEDNCADEPCSCGP	SPRY3	201	O43610
CSARDRSECPEPEDS	TMEM215	181	Q68D42
DTPNCPDASDEAACE	SPINT1	356	O43278
PCTACKSDEEERSPC	TNFRSF10A	166	O00220
EPSPCDCAETDRGDS	ZNF70	111	Q9UC06
DPTCSDCEELSCPRN	VWA7	206	Q9Y334
RCEDIDECQDPDTCS	LDLR	351	P01130
CEDDSDEQDCPPREC	LRP4	96	O75096