Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglycosaminoglycan binding

ADAMTS5 STAB2 FN1 PPIA STAB1

2.66e-04268435GO:0005539
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

STAB2 STAB1

5.33e-0416432GO:0005041
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

STAB2 STAB1

6.78e-0418432GO:0030169
GeneOntologyMolecularFunctionextracellular matrix structural constituent

CRELD2 RELN FN1 SSPOP

7.05e-04188434GO:0005201
GeneOntologyMolecularFunctioncargo receptor activity

STAB2 ABCA7 STAB1

8.12e-0485433GO:0038024
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

STAB2 STAB1

9.27e-0421432GO:0030228
GeneOntologyMolecularFunctioncalcium ion binding

CRELD2 SNED1 PLCD4 SCUBE1 STAB2 F9 STAB1

1.01e-03749437GO:0005509
GeneOntologyMolecularFunctioncyclosporin A binding

PPIAL4A PPIA

1.21e-0324432GO:0016018
GeneOntologyMolecularFunctionscavenger receptor activity

STAB2 STAB1

1.54e-0327432GO:0005044
GeneOntologyMolecularFunctionhyaluronic acid binding

STAB2 STAB1

1.77e-0329432GO:0005540
GeneOntologyMolecularFunctionmetalloendopeptidase activity

ADAMTS16 ADAMTS5 ADAMTS7

2.19e-03120433GO:0004222
GeneOntologyMolecularFunctionendopeptidase activity

ADAMTS16 CELA3B ADAMTS5 ADAMTS7 F9

2.22e-03430435GO:0004175
GeneOntologyMolecularFunctionlipoprotein particle binding

STAB2 STAB1

2.58e-0335432GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

STAB2 STAB1

2.58e-0335432GO:0071814
GeneOntologyMolecularFunctionpeptidase activity

ADAMTS16 CELA3B RELN ADAMTS5 ADAMTS7 F9

2.62e-03654436GO:0008233
GeneOntologyMolecularFunctionprotein-disulfide reductase activity

STAB2 STAB1

2.72e-0336432GO:0015035
GeneOntologyMolecularFunctiondisulfide oxidoreductase activity

STAB2 STAB1

3.87e-0343432GO:0015036
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

PPIAL4A PPIA

5.20e-0350432GO:0003755
GeneOntologyMolecularFunctioncis-trans isomerase activity

PPIAL4A PPIA

5.82e-0353432GO:0016859
GeneOntologyMolecularFunctionintegrin binding

ADAMTS5 FN1 PPIA

6.31e-03175433GO:0005178
GeneOntologyMolecularFunctionoxidoreductase activity, acting on a sulfur group of donors

STAB2 STAB1

6.71e-0357432GO:0016667
GeneOntologyCellularComponentextracellular matrix

ADAMTS16 SNED1 LOXL4 CELA3B RELN ADAMTS5 FN1 ADAMTS7 SSPOP F9

5.14e-076564210GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

ADAMTS16 SNED1 LOXL4 CELA3B RELN ADAMTS5 FN1 ADAMTS7 SSPOP F9

5.28e-076584210GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LOXL4 CELA3B RELN ADAMTS5 FN1 SSPOP F9

8.09e-05530427GO:0062023
HumanPhenoAbnormal circulating hepcidin concentration

PIGA STAB1

3.60e-054132HP:0031875
DomainEGF_1

CRELD2 SNED1 RELN SCUBE1 STAB2 FN1 TENM3 SSPOP F9 STAB1

1.89e-102554210PS00022
DomainEGF_3

CRELD2 SNED1 RELN SCUBE1 STAB2 TENM3 SSPOP F9 STAB1

2.11e-09235429PS50026
DomainEGF-like_CS

CRELD2 SNED1 RELN SCUBE1 STAB2 FN1 TENM3 F9 STAB1

5.28e-09261429IPR013032
DomainEGF_2

CRELD2 SNED1 RELN SCUBE1 STAB2 TENM3 SSPOP F9 STAB1

6.03e-09265429PS01186
DomainEGF

CRELD2 SNED1 RELN SCUBE1 STAB2 TENM3 F9 STAB1

4.55e-08235428SM00181
DomainEGF-like_dom

CRELD2 SNED1 RELN SCUBE1 STAB2 TENM3 F9 STAB1

7.12e-08249428IPR000742
DomainEGF_CA

CRELD2 SNED1 SCUBE1 STAB2 F9 STAB1

2.97e-07122426SM00179
DomainEGF-like_Ca-bd_dom

CRELD2 SNED1 SCUBE1 STAB2 F9 STAB1

3.27e-07124426IPR001881
DomainEGF_3

SCUBE1 STAB2 STAB1

2.29e-0612423PF12947
DomainEGF_dom

SCUBE1 STAB2 STAB1

2.29e-0612423IPR024731
DomainEGF_extracell

RELN STAB2 TENM3 STAB1

9.83e-0660424IPR013111
DomainEGF_2

RELN STAB2 TENM3 STAB1

9.83e-0660424PF07974
DomainTSP_1

ADAMTS16 ADAMTS5 ADAMTS7 SSPOP

1.19e-0563424PF00090
DomainTSP1

ADAMTS16 ADAMTS5 ADAMTS7 SSPOP

1.35e-0565424SM00209
DomainTSP1_rpt

ADAMTS16 ADAMTS5 ADAMTS7 SSPOP

1.35e-0565424IPR000884
DomainTSP1

ADAMTS16 ADAMTS5 ADAMTS7 SSPOP

1.35e-0565424PS50092
DomainADAM_spacer1

ADAMTS16 ADAMTS5 ADAMTS7

1.81e-0523423IPR010294
DomainADAM_spacer1

ADAMTS16 ADAMTS5 ADAMTS7

1.81e-0523423PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS16 ADAMTS5 ADAMTS7

2.07e-0524423IPR013273
DomainFAS1

STAB2 STAB1

2.95e-054422SM00554
DomainFAS1_domain

STAB2 STAB1

2.95e-054422IPR000782
Domain-

STAB2 STAB1

2.95e-0544222.30.180.10
DomainFAS1

STAB2 STAB1

2.95e-054422PS50213
DomainFasciclin

STAB2 STAB1

2.95e-054422PF02469
DomainEGF_Ca-bd_CS

CRELD2 SNED1 SCUBE1 F9

6.58e-0597424IPR018097
DomainEGF_CA

CRELD2 SNED1 SCUBE1 F9

7.12e-0599424PS01187
DomainASX_HYDROXYL

CRELD2 SNED1 SCUBE1 F9

7.41e-05100424PS00010
DomainLaminin_EGF

CRELD2 STAB2 STAB1

8.44e-0538423IPR002049
DomainPeptidase_M12B_N

ADAMTS16 ADAMTS5 ADAMTS7

9.13e-0539423IPR002870
DomainPep_M12B_propep

ADAMTS16 ADAMTS5 ADAMTS7

9.13e-0539423PF01562
DomainEGF-type_Asp/Asn_hydroxyl_site

CRELD2 SNED1 SCUBE1 F9

9.29e-05106424IPR000152
DomainDISINTEGRIN_1

ADAMTS16 ADAMTS5 ADAMTS7

9.86e-0540423PS00427
DomainReprolysin

ADAMTS16 ADAMTS5 ADAMTS7

9.86e-0540423PF01421
DomainADAM_MEPRO

ADAMTS16 ADAMTS5 ADAMTS7

9.86e-0540423PS50215
DomainDISINTEGRIN_2

ADAMTS16 ADAMTS5 ADAMTS7

9.86e-0540423PS50214
DomainPeptidase_M12B

ADAMTS16 ADAMTS5 ADAMTS7

9.86e-0540423IPR001590
DomainDisintegrin_dom

ADAMTS16 ADAMTS5 ADAMTS7

1.06e-0441423IPR001762
DomainEGF

SNED1 STAB2 F9 STAB1

1.81e-04126424PF00008
DomainBAH

RERE BAHCC1

2.68e-0411422SM00439
Domain-

STAB2 STAB1

2.68e-04114222.40.155.10
DomainGFP-like

STAB2 STAB1

2.68e-0411422IPR023413
DomainBAH

RERE BAHCC1

2.68e-0411422PF01426
DomainBAH

RERE BAHCC1

2.68e-0411422PS51038
DomainBAH_dom

RERE BAHCC1

2.68e-0411422IPR001025
DomainLINK

STAB2 STAB1

3.79e-0413422SM00445
DomainLink_dom

STAB2 STAB1

3.79e-0413422IPR000538
DomainXlink

STAB2 STAB1

3.79e-0413422PF00193
DomainLINK_1

STAB2 STAB1

3.79e-0413422PS01241
DomainLINK_2

STAB2 STAB1

3.79e-0413422PS50963
DomainGrowth_fac_rcpt_

CRELD2 SCUBE1 STAB2 STAB1

4.09e-04156424IPR009030
DomainWD40_repeat_dom

WDR45B WDR86 TENM3 DCAF8L1 WDR62

5.17e-04297425IPR017986
DomainMetalloPept_cat_dom

ADAMTS16 ADAMTS5 ADAMTS7

7.99e-0481423IPR024079
Domain-

ADAMTS16 ADAMTS5 ADAMTS7

7.99e-04814233.40.390.10
DomainPLAC

ADAMTS16 ADAMTS7

8.24e-0419422PS50900
DomainCyclophilin-type_PPIase_CS

PPIAL4A PPIA

8.24e-0419422IPR020892
DomainPLAC

ADAMTS16 ADAMTS7

8.24e-0419422IPR010909
DomainCyclophilin-type_PPIase

PPIAL4A PPIA

1.01e-0321422IPR024936
DomainSRCR

LOXL4 CD6

1.01e-0321422PF00530
DomainCyclophilin-like_dom

PPIAL4A PPIA

1.11e-0322422IPR029000
DomainCSA_PPIASE_2

PPIAL4A PPIA

1.11e-0322422PS50072
DomainPro_isomerase

PPIAL4A PPIA

1.11e-0322422PF00160
Domain-

PPIAL4A PPIA

1.11e-03224222.40.100.10
DomainCyclophilin-type_PPIase_dom

PPIAL4A PPIA

1.11e-0322422IPR002130
DomainCSA_PPIASE_1

PPIAL4A PPIA

1.11e-0322422PS00170
Domainzf-CCHC

RBM4B RBM4

1.21e-0323422PF00098
DomainZINC_PROTEASE

ADAMTS16 ADAMTS5 ADAMTS7

1.39e-0398423PS00142
DomainSR

LOXL4 CD6

1.43e-0325422SM00202
Domain-

LOXL4 CD6

1.43e-03254223.10.250.10
DomainSRCR_1

LOXL4 CD6

1.55e-0326422PS00420
Domain-

RBM4B RBM4

1.55e-03264224.10.60.10
DomainSRCR_2

LOXL4 CD6

1.55e-0326422PS50287
DomainSRCR-like_dom

LOXL4 CD6

1.55e-0326422IPR017448
DomainSRCR

LOXL4 CD6

1.67e-0327422IPR001190
DomainEGF_LAM_2

STAB2 STAB1

2.06e-0330422PS50027
DomainEGF_LAM_1

STAB2 STAB1

2.06e-0330422PS01248
DomainWD40

WDR45B WDR86 DCAF8L1 WDR62

2.67e-03259424PF00400
DomainZF_CCHC

RBM4B RBM4

2.80e-0335422PS50158
DomainEGF_Lam

STAB2 STAB1

2.80e-0335422SM00180
DomainWD40

WDR45B WDR86 DCAF8L1 WDR62

3.02e-03268424SM00320
DomainWD40_repeat

WDR45B WDR86 DCAF8L1 WDR62

3.19e-03272424IPR001680
DomainWD_REPEATS_1

WDR45B WDR86 DCAF8L1 WDR62

3.45e-03278424PS00678
DomainWD_REPEATS_2

WDR45B WDR86 DCAF8L1 WDR62

3.49e-03279424PS50082
DomainWD_REPEATS_REGION

WDR45B WDR86 DCAF8L1 WDR62

3.49e-03279424PS50294
DomainCYSTEINE_SWITCH

ADAMTS16 ADAMTS7

3.83e-0341422PS00546
DomainPept_M10_metallopeptidase

ADAMTS16 ADAMTS7

4.20e-0343422IPR001818
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS16 ADAMTS5 ADAMTS7 SSPOP

8.38e-0739274M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS16 ADAMTS5 ADAMTS7 SSPOP

8.38e-0739274MM15165
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS16 ADAMTS5 ADAMTS7 SSPOP

7.99e-0668274M27303
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS16 ADAMTS5 ADAMTS7 SSPOP

5.17e-05109274MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS16 ADAMTS5 ADAMTS7 SSPOP

5.56e-05111274M27416
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

ADAMTS16 SCUBE1 ADAMTS5 FN1

1.37e-04140274M587
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS16 ADAMTS5 ADAMTS7 SSPOP

1.49e-04143274M27275
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

ADAMTS16 LOXL4 SCUBE1 ADAMTS5 FN1

2.32e-04300275M610
PathwayWP_INTERACTIONS_BETWEEN_LOXL4_AND_OXIDATIVE_STRESS_PATHWAY

LOXL4 FN1

5.30e-0418272M39586
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTS16 ADAMTS5 ADAMTS7 SSPOP

1.23e-03250274M27554
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

SCUBE1 ADAMTS5 FN1

1.31e-03114273MM14571
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LOXL4 SCUBE1 ADAMTS5 FN1

1.38e-03258274MM14572
Pubmed

Phylogenetic and molecular characterization of the splicing factor RBM4.

RBM4B RBM4

1.56e-06244223527094
Pubmed

Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors.

STAB2 STAB1

1.56e-06244221293057
Pubmed

A Selective Extracellular Matrix Proteomics Approach Identifies Fibronectin Proteolysis by A Disintegrin-like and Metalloprotease Domain with Thrombospondin Type 1 Motifs (ADAMTS16) and Its Impact on Spheroid Morphogenesis.

ADAMTS16 FN1

1.56e-06244229669734
Pubmed

Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding.

STAB2 STAB1

1.56e-06244215572036
Pubmed

Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin-deficient mice.

STAB2 STAB1

1.56e-06244238946049
Pubmed

The LARK/RBM4a protein is highly expressed in cerebellum as compared to cerebrum.

RBM4B RBM4

1.56e-06244218708123
Pubmed

FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products.

STAB2 STAB1

1.56e-06244212473645
Pubmed

Identifying Stabilin-1 and Stabilin-2 Double Knockouts in Reproduction and Placentation: A Descriptive Study.

STAB2 STAB1

1.56e-06244233008099
Pubmed

Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues.

STAB2 STAB1

1.56e-06244211829752
Pubmed

Exploring the transcriptomic network of multi-ligand scavenger receptor Stabilin-1- and Stabilin-2-deficient liver sinusoidal endothelial cells.

STAB2 STAB1

1.56e-06244233130055
Pubmed

FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities.

STAB2 STAB1

1.56e-06244212077138
Pubmed

Stabilin-1 mediates beneficial monocyte recruitment and tolerogenic macrophage programming during CVB3-induced viral myocarditis.

FN1 STAB1

1.56e-06244234968453
Pubmed

Association of Differentially Altered Liver Fibrosis with Deposition of TGFBi in Stabilin-Deficient Mice.

STAB2 STAB1

1.56e-06244237446152
Pubmed

Scavenging Endothelium of Pancreatic Islets: Differential Expression of Stabilin-1 and Stabilin-2 in Mice and Humans.

STAB2 STAB1

1.56e-06244227977633
Pubmed

Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver.

STAB2 STAB1

1.56e-06244221427291
Pubmed

Novel transcription factor Satb2 interacts with matrix attachment region DNA elements in a tissue-specific manner and demonstrates cell-type-dependent expression in the developing mouse CNS.

RELN STAB2 STAB1

2.12e-062044315733084
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS16 ADAMTS5 ADAMTS7 SSPOP

2.54e-067544420637190
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

CRELD2 CELA3B RELN FN1 SSPOP

2.82e-0617544528071719
Pubmed

Highly oxidized albumin is cleared by liver sinusoidal endothelial cells via the receptors stabilin-1 and -2.

STAB2 STAB1

4.69e-06344237926735
Pubmed

RBM4 Regulates Neuronal Differentiation of Mesenchymal Stem Cells by Modulating Alternative Splicing of Pyruvate Kinase M.

RBM4B RBM4

4.69e-06344227821480
Pubmed

Stabilin receptors clear LPS and control systemic inflammation.

STAB2 STAB1

4.69e-06344234816100
Pubmed

A novel splicing regulator shares a nuclear import pathway with SR proteins.

RBM4B RBM4

4.69e-06344212628928
Pubmed

Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction.

ADAMTS5 FN1 ADAMTS7

9.13e-063244331434798
Pubmed

Regulated proteolytic processing of Reelin through interplay of tissue plasminogen activator (tPA), ADAMTS-4, ADAMTS-5, and their modulators.

RELN ADAMTS5

9.37e-06444223082219
Pubmed

Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18.

ADAMTS16 ADAMTS5

9.37e-06444216507336
Pubmed

Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression.

STAB2 STAB1

9.37e-06444236325910
Pubmed

Deficiency for scavenger receptors Stabilin-1 and Stabilin-2 leads to age-dependent renal and hepatic depositions of fasciclin domain proteins TGFBI and Periostin in mice.

STAB2 STAB1

9.37e-06444237357460
Pubmed

Regulation of aggrecanases from the ADAMTS family and aggrecan neoepitope formation during in vitro chondrogenesis of human mesenchymal stem cells.

ADAMTS16 ADAMTS5

1.56e-05544222562232
Pubmed

Comparison of the four mouse fasciclin-containing genes expression patterns during valvuloseptal morphogenesis.

STAB2 STAB1

1.56e-05544215907457
Pubmed

RBM4 promotes neuronal differentiation and neurite outgrowth by modulating Numb isoform expression.

RBM4B RBM4

2.34e-05644227009199
Pubmed

LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1.

RBM4B RBM4

3.27e-05744217264215
Pubmed

Activation of TrkB signaling mitigates cerebellar anomalies caused by Rbm4-Bdnf deficiency.

RBM4B RBM4

5.60e-05944237670183
Pubmed

ADAMTS: a novel family of extracellular matrix proteases.

ADAMTS5 ADAMTS7

6.99e-051044211167130
Pubmed

Zinc transporter Slc39a8 is essential for cardiac ventricular compaction.

ADAMTS5 ADAMTS7

8.54e-051144229337306
Pubmed

Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development.

ADAMTS5 FN1

8.54e-051144238750698
Pubmed

Searching QTL by gene expression: analysis of diabesity.

CELA3B PLCD4 FN1

1.02e-047144315760467
Pubmed

RBM4 Modulates Radial Migration via Alternative Splicing of Dab1 during Cortex Development.

RBM4B RBM4

1.02e-041244229581187
Pubmed

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

ADAMTS5 ADAMTS7

1.02e-041244225770910
Pubmed

E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3.

FN1 RBM4

1.63e-041544218276110
Pubmed

Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation.

ADAMTS16 FN1

1.63e-041544238018454
Pubmed

ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.

ADAMTS16 ADAMTS5

1.86e-041644230579834
Pubmed

RBM4 promotes pancreas cell differentiation and insulin expression.

RBM4B RBM4

2.10e-041744223129807
Pubmed

ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family.

ADAMTS5 ADAMTS7

2.10e-041744210464288
Pubmed

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

ZBTB46 CD6 ALPK2

2.12e-049144321833088
Pubmed

Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly.

RELN WDR62

2.36e-041844228272472
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

ADAMTS5 FN1 ADAMTS7 PPIA

2.74e-0424844424006456
Pubmed

Integration of H-2Z1, a somatosensory cortex-expressed transgene, interferes with the expression of the Satb1 and Tbc1d5 flanking genes and affects the differentiation of a subset of cortical interneurons.

RELN STAB2

2.93e-042044222623674
Pubmed

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.

RBM4B RBM4 STAB1

2.97e-0410244321926972
Pubmed

Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex.

RELN FN1

6.65e-043044218055048
Pubmed

Molecular profiling of the vestibular lamina highlights a key role for Hedgehog signalling.

SNED1 SCUBE1

7.11e-043144236971701
Pubmed

Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth.

SCUBE1 FN1

8.06e-043344226952977
Pubmed

Galnt1 is required for normal heart valve development and cardiac function.

ADAMTS5 FN1

9.59e-043644225615642
Pubmed

Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.

ADAMTS16 FN1

1.01e-033744234323105
Pubmed

Epicardial cell shape and maturation are regulated by Wt1 via transcriptional control of Bmp4.

RELN FN1

1.07e-033844231624071
Pubmed

Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation.

ADAMTS5 FN1

1.07e-033844229743679
Cytoband11q13

CD6 RBM4B RBM4

2.17e-0411845311q13
Cytoband12q23.3

WSCD2 STAB2

5.48e-043545212q23.3
Cytoband1q21.1

ANKRD34A PPIAL4A

1.71e-03624521q21.1
Cytoband7q36.1

WDR86 SSPOP

2.43e-03744527q36.1
CytobandEnsembl 112 genes in cytogenetic band chr17q25

WDR45B ACOX1 BAHCC1

3.41e-03307453chr17q25
Cytoband17q25.3

WDR45B BAHCC1

4.46e-0310145217q25.3
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS16 ADAMTS5 ADAMTS7

3.17e-061928350
GeneFamilyWD repeat domain containing

WDR45B WDR86 DCAF8L1 WDR62

6.71e-04262284362
GeneFamilyZinc fingers CCHC-type|RNA binding motif containing

RBM4B RBM4

6.79e-042528274
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

STAB2 STAB1

7.93e-04272821253
CoexpressionNABA_MATRISOME

ADAMTS16 CRELD2 SNED1 LOXL4 CELA3B RELN SCUBE1 ADAMTS5 FN1 ADAMTS7 SSPOP F9

6.63e-0810084412MM17056
CoexpressionNABA_MATRISOME

ADAMTS16 CRELD2 SNED1 LOXL4 CELA3B RELN SCUBE1 ADAMTS5 FN1 ADAMTS7 SSPOP F9

8.04e-0810264412M5889
CoexpressionNABA_ECM_REGULATORS

ADAMTS16 LOXL4 CELA3B ADAMTS5 ADAMTS7 F9

2.78e-06238446M3468
CoexpressionNABA_ECM_REGULATORS

ADAMTS16 LOXL4 CELA3B ADAMTS5 ADAMTS7 F9

3.06e-06242446MM17062
CoexpressionNABA_ECM_GLYCOPROTEINS

CRELD2 SNED1 RELN FN1 SSPOP

1.68e-05191445MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

CRELD2 SNED1 RELN FN1 SSPOP

1.90e-05196445M3008
CoexpressionNABA_CORE_MATRISOME

CRELD2 SNED1 RELN FN1 SSPOP

8.74e-05270445MM17057
CoexpressionNABA_CORE_MATRISOME

CRELD2 SNED1 RELN FN1 SSPOP

9.53e-05275445M5884
CoexpressionAIZARANI_LIVER_C13_LSECS_2

RELN IFI44L STAB2 EXOC3L2 STAB1

1.09e-04283445M39117
CoexpressionAIZARANI_LIVER_C9_LSECS_1

RELN IFI44L STAB2 EXOC3L2 STAB1

1.52e-04304445M39113
CoexpressionAtlasratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#2

LOXL4 RELN ADAMTS5 FN1 ALPK2 BAHCC1

1.15e-06170436ratio_DE_vs_SC_500_K2
CoexpressionAtlasratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_500

LOXL4 RELN ADAMTS5 FN1 MARCHF11 ALPK2 BAHCC1

5.59e-05495437PCBC_ratio_DE_vs_SC_500
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#3_top-relative-expression-ranked_100

STAB2 EXOC3L2 STAB1

1.11e-0446433DevelopingKidney_e15.5_Endothelial cells_emap-29977_k3_100
CoexpressionAtlasratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_1000

LOXL4 ATP13A4 RELN SCUBE1 WDR86 AFDN-DT SSPOP ALPK2 BAHCC1

1.31e-04986439PCBC_ratio_ECTO_vs_SC_1000
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNED1 RELN ADAMTS5 STAB2 TENM3 STAB1

3.72e-08190456e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNED1 RELN ADAMTS5 STAB2 TENM3 STAB1

3.72e-08190456f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNED1 RELN ADAMTS5 STAB2 TENM3 STAB1

3.72e-08190456b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SCUBE1 IFI44L EXOC3L2 ZKSCAN4 FN1

6.98e-071664559d4b44eb56ad38c26aed73444edf389abca6bdf6
ToppCellEndothelial-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

PLCD4 RELN ADAMTS5 STAB2 AFDN-DT

7.62e-071694558889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

RELN STAB2 FN1 ADAMTS7 SSPOP

8.32e-07172455c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCellEndothelial-Endothelial-G|Endothelial / shred on cell class and cell subclass (v4)

SNED1 RELN STAB2 FN1 STAB1

8.32e-07172455644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCellP28-Endothelial-lymphatic_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SNED1 RELN STAB2 PPIA STAB1

9.58e-071774556e330aa3c87fd640526b746a9deb3b2250d2518c
ToppCellP28-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SNED1 RELN STAB2 PPIA STAB1

9.58e-07177455e96a7e4544710aaab8bd2800ecff9667880a8bf4
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTS16 WSCD2 RELN TENM3 ALPK2

9.85e-07178455544379f5a6145429762258d426b876bb36c112f5
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

WSCD2 LOXL4 RELN TENM3 ALPK2

1.01e-06179455e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS16 ATP13A4 RELN STAB2 SSPOP

1.16e-061844552cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS16 ATP13A4 RELN STAB2 SSPOP

1.16e-06184455ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS16 ATP13A4 RELN STAB2 SSPOP

1.16e-061844552b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WSCD2 LOXL4 RELN TENM3 ALPK2

1.29e-06188455b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WSCD2 LOXL4 RELN TENM3 ALPK2

1.29e-06188455874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell21-Trachea-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

RELN IFI44L STAB2 EXOC3L2 STAB1

1.36e-06190455bce09634acbc2cfd53666328e8aed8bf8835f845
ToppCell21-Trachea-Endothelial-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

RELN IFI44L STAB2 EXOC3L2 STAB1

1.36e-0619045508437396a98ca9526f69c3a74bbf2929f3c68b8e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB46 RELN SCUBE1 EXOC3L2 FN1

1.50e-06194455b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB46 RELN IFI44L EXOC3L2 FN1

1.50e-06194455fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

SNED1 SCUBE1 EXOC3L2 FN1 STAB1

1.54e-06195455a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

SNED1 ZBTB46 RELN STAB2 STAB1

1.58e-06196455e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SCUBE1 IFI44L EXOC3L2 FN1 STAB1

1.58e-0619645595c5b8fd4ebfae1f42de9b1475c1161d4a80e515
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

WSCD2 SNED1 SCUBE1 FN1 WDR62

1.62e-061974552cb1f557ce1400398975de94638126b4522567f3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCUBE1 IFI44L EXOC3L2 FN1 STAB1

1.66e-06198455259fbcc0f2ac281a3e4d693de45b986fe5e24841
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

WSCD2 SNED1 SCUBE1 FN1 WDR62

1.70e-06199455fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS16 WSCD2 RELN TENM3 ALPK2

1.70e-06199455b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS16 WSCD2 RELN TENM3 ALPK2

1.70e-06199455c972d3036151403f26fa9d6271520639c281ab84
ToppCellGlobus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Gfap_(Gfap)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ATP13A4 IFI44L STAB2 SDS

3.88e-06105454c41264e8b7d306d5d3ffa5b29eb36c7131d1cedf
ToppCellGlobus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Gfap_(Gfap)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ATP13A4 IFI44L STAB2 SDS

3.88e-06105454ed570cfdd452767dfb4dcae72282fe0fb25a4029
ToppCellGlobus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Gfap_(Gfap)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ATP13A4 IFI44L STAB2 SDS

3.88e-06105454ed3a431195c42c96c7d9c420e4b9fb00f415012d
ToppCellGlobus_pallidus-Macroglia-ASTROCYTE-Gja1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ATP13A4 IFI44L STAB2 SDS

4.84e-061114547d7aad8e9811c67fb9abfb4ebc75def01a517adf
ToppCellGlobus_pallidus-Macroglia-ASTROCYTE|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ATP13A4 IFI44L STAB2 SDS

4.84e-06111454cb45322fbeafec2f1ab7a3727da69abb1047567d
ToppCellEndothelial-G|World / shred on cell class and cell subclass (v4)

SNED1 RELN STAB2 STAB1

7.50e-061244544b72809463f2986b7d1b7ab9de633ac4d7854a92
ToppCell10x5'-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

ZBTB46 SDS ALPK2 STAB1

1.25e-051414547671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WSCD2 STAB2 TENM3 ALPK2

1.55e-05149454cc6224c6b79f43b97adc1ce48ca4906bff2ad318
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WSCD2 STAB2 TENM3 ALPK2

1.55e-0514945424a7538b54b2a5291503c7493fefed4e45e8d710
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RELN ALPK2 BAHCC1 STAB1

1.76e-05154454c6ecc46b99a783373729f7fae0b23216148ffb78
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 RELN STAB2 STAB1

2.26e-051644544cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 RELN STAB2 STAB1

2.26e-051644547a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 RELN STAB2 STAB1

2.26e-051644545e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCellPND10-Endothelial-Endothelial_lymphatic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 RELN STAB2 STAB1

2.26e-05164454f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN STAB2 MARCHF11 STAB1

2.31e-05165454347b59aa625a8a960828b8620824d8ac48990e07
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN STAB2 MARCHF11 STAB1

2.31e-05165454507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN STAB2 MARCHF11 STAB1

2.31e-0516545439a25be081a5d59c7cf107a997d352793d5025fb
ToppCellPND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN STAB2 MARCHF11 STAB1

2.31e-051654541890f9c33b0c5b381d57f97042da2610a093a6de
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB46 FN1 WDR62 BAHCC1

2.48e-051684542e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTS16 WSCD2 TENM3 ALPK2

2.48e-05168454a086c306be430adf0632ba53e98cd8014d2de330
ToppCellEndothelial-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

PPIAL4A RELN ADAMTS5 STAB2

2.48e-051684544977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCellEndothelial-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

RELN ADAMTS5 STAB2 TENM3

2.54e-0516945495c617143e1fbdd1d55a93ffdcc210e0be37cf2f
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN STAB2 MARCHF11 STAB1

2.60e-0517045435e3945d8a540a3e2cec1b559316265aaad023d1
ToppCellPND01-Endothelial-Endothelial_lymphatic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN STAB2 MARCHF11 STAB1

2.60e-051704540ea625abaa25bab93b70b7000e8f90d5c0f9a0fb
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN STAB2 MARCHF11 STAB1

2.60e-051704540b5ddc7d452db0a389927a367914f7d257703f7e
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLCD4 RELN STAB2 FN1

2.60e-051704544848965bc7e9356c6601bb41eeea1553d2eea87e
ToppCellEndothelial-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

RELN ADAMTS5 STAB2 TENM3

2.66e-0517145407ff7059071da83da1d8f266a586573920d75b58
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB46 WDR86 SSPOP BAHCC1

2.84e-051744547be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB46 PIGA PRICKLE3 ABCA7

2.84e-05174454ff13a5c55d18b951315908f33cb47c7f9cb901bf
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZBTB46 WDR86 SSPOP BAHCC1

2.91e-051754541b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCellP15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RELN STAB2 MARCHF11 STAB1

2.91e-0517545484d252f3e432231687613299bbea14978bb4b06b
ToppCellP15-Endothelial-lymphatic_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RELN STAB2 MARCHF11 STAB1

2.91e-05175454a00c6fa9b33640710dd05a3799031147196f0986
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Cst3_(Cst3)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

STAB2 SDS ALPK2

2.92e-05594531b89466083bb454812e150137514300aa8228828
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Cst3_(Cst3)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

STAB2 SDS ALPK2

2.92e-0559453e81235f93aaf7f373d7cbd00882e32b73da29633
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Cst3_(Cst3)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

STAB2 SDS ALPK2

2.92e-05594534f0bfb48c0a98487f37da31e14e64282c70d5e66
ToppCellEndothelial-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

RELN ADAMTS5 STAB2 TENM3

2.97e-05176454b288116a4588a1f9db9d49af92cea118937c9201
ToppCell3'_v3-blood-Mast-Mast_cells|blood / Manually curated celltypes from each tissue

WSCD2 SCUBE1 PRICKLE3 ACOX1

2.97e-05176454b9da3deaf62622d47eb30b6be7548253eee95597
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 ZBTB46 EXOC3L2 F9

2.97e-05176454dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-chondrocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

WSCD2 LOXL4 FN1 TENM3

3.04e-05177454915b848d789051a1c3bc6f6dc86955bb752276ab
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

ADAMTS16 ADAMTS5 TENM3 ALPK2

3.18e-05179454cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNED1 RELN STAB2 STAB1

3.39e-051824542cc434e46985c66fc36de05344a67aa96d90abc9
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNED1 RELN STAB2 STAB1

3.39e-051824540cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNED1 RELN STAB2 STAB1

3.39e-051824543e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN STAB2 MARCHF11 STAB1

3.39e-05182454fc020d784ab81af80d9331cc322b7c259284eaef
ToppCellP03-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RELN STAB2 MARCHF11 STAB1

3.46e-0518345489727b4f65949ed2dce9d2e0228c79fe4280230c
ToppCellP03-Endothelial-lymphatic_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RELN STAB2 MARCHF11 STAB1

3.46e-05183454113e6d8d4bb271be984af06cd6c22b180425dcfc
ToppCelldroplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN PIGA WDR62 STAB1

3.61e-051854546a85399cfdb9b89683c874e7f046957f9a601dc2
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

WSCD2 ADAMTS5 FN1 TENM3

3.61e-05185454c85bba1210f1d389add3e40be9b96abac40cf8c1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WSCD2 RELN TENM3 ALPK2

3.61e-0518545434fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCelldroplet-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN PIGA WDR62 STAB1

3.61e-0518545464791056cdbb739136dbef08f4b16e2b5427faad
ToppCellEndoth-Lymph|World / shred by cell class for parenchyma

RELN ADAMTS5 STAB2 STAB1

3.61e-0518545497a6c4cd00684d4085d36ef32f7dbb99563ed357
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WSCD2 RELN TENM3 ALPK2

3.61e-051854548816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellNS-critical-d_16-33-Myeloid-Monocyte-derived_DC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FN1 PPIA SDS STAB1

3.85e-0518845408eb1e4b719af53c52895557523d0a1b7421d849
ToppCelldroplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNED1 RELN STAB2 STAB1

3.85e-05188454a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RELN STAB2 FN1 ADAMTS7

3.85e-0518845426915db8863f4115b46a81982e187322e21600fd
ToppCelldroplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNED1 RELN STAB2 STAB1

3.85e-0518845454550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RELN STAB2 FN1 ADAMTS7

3.85e-051884543f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-chondrocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

WSCD2 LOXL4 PLCD4 FN1

3.85e-051884545a89587ee6f2b4dc14244bd88bb31efb81c50dbe
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RELN STAB2 FN1 ADAMTS7

3.85e-0518845461ee7b152745164293d8a44ef91ee2393efbdca5
ToppCellEC-Sinusoidal_ECs|World / Lineage and Cell class

RELN STAB2 EXOC3L2 STAB1

3.93e-051894549a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RELN STAB2 FN1 TENM3

4.01e-051904549ce301841ce9486701fa28eb2a9929e35d476878
ToppCellFibroblasts-CD55+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

ADAMTS16 ADAMTS5 FN1 ABCA7

4.01e-05190454b4088128f5acf53f43244c9af9fe44e033f1a57a
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNED1 RELN STAB2 STAB1

4.01e-05190454a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNED1 RELN STAB2 STAB1

4.01e-051904540bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNED1 RELN STAB2 STAB1

4.01e-0519045426e2237f65cb43723c5da853831b40df2982d6e4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB46 RELN EXOC3L2 FN1

4.09e-05191454f663131a4810584c5854bd64ee7991a237b7707f
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SNED1 WDR86 FN1 TENM3

4.09e-0519145408720998aa55131d7377c4c67c4c935865bd7d79
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNED1 RELN STAB2 STAB1

4.09e-0519145448823a97c38263f2c6e58348214f5b62773a6368
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNED1 RELN STAB2 STAB1

4.09e-051914540eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 SCUBE1 IFI44L EXOC3L2

4.18e-051924541ee4783051ec94ea94600f040edcb385fc4289f1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IFI44L EXOC3L2 FN1 STAB1

4.18e-0519245425cb6cc6cbf8dc20139d938adfc02ed7a8c3dfb6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB46 IFI44L EXOC3L2 FN1

4.18e-0519245428eb3a5728e8901bcb5ba12f6b009f41b065fa37
DrugDichloroacetic Acid

CRELD2 SNED1 LOXL4 CELA3B PLCD4 IFI44L TENM3 ADAMTS7 ACOX1 ALPK2

9.74e-069674310ctd:D003999
DrugOxamniquine [21738-42-1]; Up 200; 14.4uM; MCF7; HT_HG-U133A

SNED1 RERE PRICKLE3 ABCA7 WDR62

3.24e-051954354124_UP
DrugVinpocetine [42971-09-5]; Up 200; 11.4uM; PC3; HT_HG-U133A

STAB2 CD6 PRICKLE3 ABCA7 WDR62

3.40e-051974355859_UP
DrugChelidonine monohydrate (+) [476-32-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A

STAB2 CD6 FN1 WDR62 STAB1

3.40e-051974352779_UP
DrugGLA-27

RELN F9

3.47e-055432CID000163574
Drug(R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; MCF7; HT_HG-U133A

STAB2 FN1 TENM3 SIPA1L3 BAHCC1

3.48e-051984356096_DN
DrugIobenguane sulfate; Up 200; 10.8uM; PC3; HT_HG-U133A

RERE PRICKLE3 ABCA7 SIPA1L3 STAB1

3.48e-051984357299_UP
DrugSulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A

SNED1 RERE CD6 SDS SIPA1L3

3.65e-052004354740_UP
Diseasefamily history of Alzheimer’s disease

EXOC3L2 ABCA7 ALPK2

1.54e-0471433EFO_0009268
Diseaseserum gamma-glutamyl transferase measurement

ZBTB46 AFDN-DT PPIA ALPK2 SIPA1L3 BAHCC1 STAB1

3.25e-04914437EFO_0004532
DiseaseInvolutional paraphrenia

RELN IFI44L

6.09e-0425432C1571983
DiseasePsychosis, Involutional

RELN IFI44L

6.09e-0425432C1571984
DiseaseInvolutional Depression

RELN IFI44L

6.09e-0425432C0011574
DiseasePeriodontal Pocket

IFI44L TENM3

6.09e-0425432EFO_1001393
DiseaseAlzheimer disease, family history of Alzheimer’s disease

EXOC3L2 ABCA7 ALPK2

7.02e-04119433EFO_0009268, MONDO_0004975
Diseaseferritin measurement

FN1 TENM3 STAB1

7.02e-04119433EFO_0004459
Diseaseosteoarthritis (is_marker_for)

ADAMTS5 FN1

1.20e-0335432DOID:8398 (is_marker_for)
Diseaseanthropometric measurement

WSCD2 ADAMTS5 FN1

1.89e-03168433EFO_0004302
Diseaseurinary albumin to creatinine ratio

ZBTB46 BAHCC1 STAB1

2.27e-03179433EFO_0007778

Protein segments in the cluster

PeptideGeneStartEntry
GERMAHCCLGGLAEF

EXOC3L2

81

Q2M3D2
GLDMSCHACLSAGTG

ERC2-IT1

56

O76042
NGEMGRAALASCAGG

BAHCC1

291

Q9P281
LGGCEHFLSGMGCGS

ALPK2

371

Q86TB3
CGDGANDCGALKMAH

ATP13A4

846

Q4VNC1
CGHHSCDTLGMADVG

ADAMTS5

371

Q9UNA0
MGAAGSDGRCCVRSG

AFDN-DT

1

Q9Y6Z5
CSVSCGGGQMTVREG

ADAMTS16

881

Q8TE57
GAMEDRCGVCHGNGS

ADAMTS7

681

Q9UKP4
MEDGSCGQHLCTGIA

ABCA7

1156

Q8IZY2
LMHACAGGGGAAVAS

ANKRD34A

81

Q69YU3
MGDQSGCYRCGKEGH

RBM4

156

Q9BWF3
GGGACAGRVEMLEHG

CD6

166

P30203
SHGGGRFLAGVSCMD

LOXL4

516

Q96JB6
CDTMGLDGAEGAGLC

IFI44L

261

Q53G44
CAGFHEGGRDSCQGD

F9

396

P00740
MGDQSGCYRCGKEGH

RBM4B

156

Q9BQ04
YIGDGCIDMCSGHGR

RELN

2476

P78509
CDGCGEHIGLDQGQM

PRICKLE3

311

O43900
MCQGGDFTRHNGTGD

PPIAL4A

61

Q9Y536
NTGIEACRMACGGHG

ACOX1

386

Q15067
GHMMRCTCVGNGRGE

FN1

491

P02751
TMVCAGGDIRSGCNG

CELA3B

201

P08861
MSFEGGHGGSRCRGA

MARCHF11

1

A6NNE9
CGDSTLAMCGHDGQV

DCAF8L1

251

A6NGE4
GDGSRQGDGSCRCHM

CRELD2

156

Q6UXH1
GTHFGGELGQCVSCM

SCUBE1

636

Q8IWY4
GCAHFVCSSAGNAGM

SDS

56

P20132
GCGEGQMTCSSGHCL

SSPOP

1416

A2VEC9
MDICDGHFRQNGGCG

PLCD4

586

Q9BRC7
MCQGGDFTRHNGTGG

PPIA

61

P62937
MGLCGGGREAAGRSH

SIPA1L3

1341

O60292
DHGCFACGMENGFRV

WDR45B

21

Q5MNZ6
AGMCDGGSTEDGCVA

RERE

341

Q9P2R6
NTQCPDGGYCMEHGG

SNED1

511

Q8TER0
MACRGGAGNGHRASA

PIGA

1

P37287
NGHGTCLDGMDRNGT

STAB1

121

Q9NY15
NGRGSCAEGMEGNGT

STAB2

121

Q8WWQ8
CSVDCGSHGVCMGGT

TENM3

681

Q9P273
GSHGVCMGGTCRCEE

TENM3

686

Q9P273
CGVACGRGRMAGSTF

WDR62

256

O43379
MCDVSGGGGECVSGS

ZNF516-DT

116

Q6ZTR6
GLAQGGCCREDAMVA

ZKSCAN4

196

Q969J2
DMECKGERGSVCGGA

WSCD2

196

Q2TBF2
MGGGGSALRVCADHR

WDR86

1

Q86TI4
CTDCAGRGMAGPLDH

ZBTB46

501

Q86UZ6