Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionchromatin binding

NCOA2 NCOA1 FOXP1 THRA SALL1 EP400 EP300 ESR1 NOTCH1

1.20e-06739319GO:0003682
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

NCOA2 BPTF SP2 FOXP1 SP4 ZFHX3 THRA SALL1 EP300 ESR1 NOTCH1

1.72e-0612713111GO:0000987
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

NCOA2 NCOA1 BPTF SP2 FOXP1 SP4 ZFHX3 THRA SALL1 EP300 ESR1

6.58e-0614593111GO:0000977
GeneOntologyMolecularFunctionnuclear receptor binding

NCOA2 NCOA1 FOXP1 EP300 ESR1

9.52e-06187315GO:0016922
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

NCOA2 BPTF SP2 FOXP1 SP4 ZFHX3 THRA SALL1 EP300 ESR1

1.13e-0512443110GO:0000978
GeneOntologyMolecularFunctiontranscription factor binding

NCOA2 NCOA1 BPTF FOXP1 THRA SALL1 EP300 ESR1

1.44e-05753318GO:0008134
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

NCOA2 NCOA1 FOXP1 SALL1 EP300 ESR1

3.78e-05417316GO:0061629
GeneOntologyMolecularFunctionnuclear estrogen receptor binding

NCOA2 NCOA1 ESR1

7.53e-0553313GO:0030331
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

NCOA2 NCOA1 FOXP1 SALL1 EP300 ESR1

2.36e-04582316GO:0140297
GeneOntologyMolecularFunctionprotein antigen binding

EP400 EP300

2.76e-0416312GO:1990405
GeneOntologyMolecularFunctionintronic transcription regulatory region sequence-specific DNA binding

NCOA2 THRA

3.13e-0417312GO:0001161
GeneOntologyMolecularFunctionnuclear glucocorticoid receptor binding

NCOA2 EP300

4.36e-0420312GO:0035259
GeneOntologyMolecularFunctionRNA stem-loop binding

RC3H2 RC3H1

4.81e-0421312GO:0035613
GeneOntologyMolecularFunctionnuclear retinoid X receptor binding

NCOA2 NCOA1

5.78e-0423312GO:0046965
GeneOntologyMolecularFunctionbeta-catenin binding

SALL1 EP300 ESR1

8.41e-04120313GO:0008013
GeneOntologyMolecularFunctionmolecular adaptor activity

NCOA2 NCOA1 SUPT20HL1 FCRL2 SGTB COL19A1 EP300 NOTCH1

8.54e-041356318GO:0060090
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

SP2 FOXP1 SP4 ZFHX3 THRA SALL1 ESR1 NOTCH1

1.11e-031412318GO:0000981
GeneOntologyMolecularFunctiontranscription coactivator activity

NCOA2 NCOA1 EP300 NOTCH1

1.18e-03303314GO:0003713
GeneOntologyMolecularFunctionnuclear androgen receptor binding

FOXP1 EP300

1.20e-0333312GO:0050681
GeneOntologyMolecularFunctionTBP-class protein binding

THRA ESR1

1.20e-0333312GO:0017025
GeneOntologyMolecularFunctiontranscription coregulator binding

FOXP1 EP300 ESR1

1.31e-03140313GO:0001221
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

SP2 FOXP1 ZFHX3 SALL1

1.45e-03320314GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

SP2 FOXP1 ZFHX3 SALL1

1.55e-03326314GO:0001217
GeneOntologyMolecularFunctiontranscription coregulator activity

NCOA2 NCOA1 SUPT20HL1 EP300 NOTCH1

1.61e-03562315GO:0003712
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

NCOA2 NCOA1 SUPT20HL1 FCRL2 COL19A1 EP300 NOTCH1

1.68e-031160317GO:0030674
GeneOntologyMolecularFunctionchromatin DNA binding

THRA EP300 NOTCH1

2.17e-03167313GO:0031490
GeneOntologyMolecularFunctionhistone acetyltransferase activity

NCOA1 EP300

2.84e-0351312GO:0004402
GeneOntologyMolecularFunctiontranscription coactivator binding

EP300 ESR1

3.17e-0354312GO:0001223
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

NCOA1 EP300

3.29e-0355312GO:0061733
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

NCOA2 NCOA1

3.29e-0355312GO:0042974
GeneOntologyMolecularFunctionnuclear receptor activity

THRA ESR1

3.90e-0360312GO:0004879
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

NCOA1 EP300

3.90e-0360312GO:0034212
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

NCOA2 NCOA1

4.03e-0361312GO:0030374
GeneOntologyMolecularFunctionligand-activated transcription factor activity

THRA ESR1

4.03e-0361312GO:0098531
GeneOntologyMolecularFunctionHsp70 protein binding

SGTB ERN1

4.29e-0363312GO:0030544
GeneOntologyMolecularFunctiongeneral transcription initiation factor binding

THRA ESR1

4.43e-0364312GO:0140296
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

SCAF8 ESR1

4.70e-0366312GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

SCAF8 ESR1

4.70e-0366312GO:0001098
GeneOntologyMolecularFunctiondouble-stranded RNA binding

RC3H2 RC3H1

6.51e-0378312GO:0003725
GeneOntologyMolecularFunctionN-acetyltransferase activity

NCOA1 EP300

6.51e-0378312GO:0008080
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

EP300 ESR1

7.34e-0383312GO:1990841
GeneOntologyMolecularFunctionprotein dimerization activity

NCOA2 NCOA1 THRA SGTB ERN1 MMUT

9.56e-031205316GO:0046983
GeneOntologyMolecularFunctionN-acyltransferase activity

NCOA1 EP300

1.09e-02102312GO:0016410
GeneOntologyMolecularFunctionhormone binding

THRA ESR1

1.11e-02103312GO:0042562
GeneOntologyMolecularFunctionzinc ion binding

ZFHX3 THRA EP300 ESR1 RC3H1

1.13e-02891315GO:0008270
GeneOntologyMolecularFunctionacetyltransferase activity

NCOA1 EP300

1.13e-02104312GO:0016407
GeneOntologyMolecularFunctionsingle-stranded RNA binding

PATL2 THRA

1.28e-02111312GO:0003727
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

BPTF EP400

1.65e-02127312GO:0008094
GeneOntologyBiologicalProcesspositive regulation of female receptivity

NCOA2 NCOA1 THRA

1.23e-084313GO:0045925
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

NCOA2 NCOA1 FOXP1 THRA MN1 EP300 ESR1

1.68e-08202317GO:0141193
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

NCOA2 NCOA1 FOXP1 THRA MN1 EP300 ESR1

6.14e-08244317GO:0009755
GeneOntologyBiologicalProcessT follicular helper cell differentiation

FOXP1 RC3H2 RC3H1

1.07e-077313GO:0061470
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

NCOA2 BPTF SP2 FOXP1 ZFHX3 THRA SALL1 SCAF8 EP300 ESR1 NOTCH1

1.92e-0710533111GO:0000122
GeneOntologyBiologicalProcessregulation of female receptivity

NCOA2 NCOA1 THRA

2.57e-079313GO:0045924
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

NCOA2 NCOA1 SUPT20HL1 BPTF FOXP1 ZFHX3 PRDM10 THRA SALL1 EP300 ESR1 NOTCH1

3.55e-0713903112GO:0045944
GeneOntologyBiologicalProcessfemale mating behavior

NCOA2 NCOA1 THRA

6.70e-0712313GO:0060180
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

NCOA2 NCOA1 FOXP1 THRA MN1 EP300 ESR1

2.23e-06416317GO:0030522
GeneOntologyBiologicalProcessT-helper 17 type immune response

RC3H2 EP300 RC3H1 NOTCH1

2.49e-0664314GO:0072538
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

NCOA2 BPTF SP2 FOXP1 ZFHX3 THRA SALL1 SCAF8 EP300 ESR1 NOTCH1

3.21e-0613993111GO:0045892
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

NCOA2 BPTF SP2 FOXP1 ZFHX3 THRA SALL1 SCAF8 EP300 ESR1 NOTCH1

3.53e-0614133111GO:1902679
GeneOntologyBiologicalProcessmRNA metabolic process

CTNNBL1 NCOA2 NCOA1 PATL2 RC3H2 THRA ERN1 SCAF8 RC3H1

5.43e-06917319GO:0016071
GeneOntologyBiologicalProcesscellular response to hormone stimulus

NCOA2 NCOA1 FOXP1 THRA MN1 EP300 ESR1 NOTCH1

8.80e-06727318GO:0032870
GeneOntologyBiologicalProcessT-helper cell differentiation

FOXP1 RC3H2 EP300 RC3H1

1.06e-0592314GO:0042093
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell differentiation involved in immune response

FOXP1 RC3H2 EP300 RC3H1

1.16e-0594314GO:0002294
GeneOntologyBiologicalProcessalpha-beta T cell differentiation involved in immune response

FOXP1 RC3H2 EP300 RC3H1

1.21e-0595314GO:0002293
GeneOntologyBiologicalProcesspositive regulation of intracellular signal transduction

NCOA2 RC3H2 THRA ERN1 MN1 NEK10 EP300 ESR1 RC3H1 NOTCH1

1.24e-0512993110GO:1902533
GeneOntologyBiologicalProcesscellular response to Thyroglobulin triiodothyronine

NCOA2 NCOA1

1.31e-054312GO:1904017
GeneOntologyBiologicalProcessalpha-beta T cell activation involved in immune response

FOXP1 RC3H2 EP300 RC3H1

1.37e-0598314GO:0002287
GeneOntologyBiologicalProcessrhythmic process

NCOA2 NCOA1 ZFHX3 EP300 ESR1 NOTCH1

1.38e-05360316GO:0048511
GeneOntologyBiologicalProcessregulation of T-helper 17 cell differentiation

RC3H2 EP300 RC3H1

1.63e-0533313GO:2000319
GeneOntologyBiologicalProcessT cell differentiation involved in immune response

FOXP1 RC3H2 EP300 RC3H1

1.66e-05103314GO:0002292
GeneOntologyBiologicalProcessregulation of miRNA metabolic process

RC3H2 EP300 ESR1 RC3H1

1.66e-05103314GO:2000628
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell differentiation

FOXP1 RC3H2 EP300 RC3H1

2.94e-05119314GO:0043367
GeneOntologyBiologicalProcessmiRNA metabolic process

RC3H2 EP300 ESR1 RC3H1

2.94e-05119314GO:0010586
GeneOntologyBiologicalProcessresponse to Thyroglobulin triiodothyronine

NCOA2 NCOA1

3.27e-056312GO:1904016
GeneOntologyBiologicalProcesspositive regulation of hydrogen peroxide-mediated programmed cell death

FOXP1 EP300

4.57e-057312GO:1901300
GeneOntologyBiologicalProcesslung development

FOXP1 RC3H2 THRA EP300 NOTCH1

4.68e-05269315GO:0030324
GeneOntologyBiologicalProcessT-helper 17 cell differentiation

RC3H2 EP300 RC3H1

4.77e-0547313GO:0072539
GeneOntologyBiologicalProcessregulation of T-helper 17 type immune response

RC3H2 EP300 RC3H1

4.77e-0547313GO:2000316
GeneOntologyBiologicalProcessnuclear receptor-mediated steroid hormone signaling pathway

NCOA2 FOXP1 EP300 ESR1

4.96e-05136314GO:0030518
GeneOntologyBiologicalProcessrespiratory tube development

FOXP1 RC3H2 THRA EP300 NOTCH1

5.02e-05273315GO:0030323
GeneOntologyBiologicalProcessregulation of thyroid hormone receptor signaling pathway

NCOA1 THRA

6.09e-058312GO:0002155
GeneOntologyBiologicalProcessmRNA transcription by RNA polymerase II

NCOA2 NCOA1 THRA

6.46e-0552313GO:0042789
GeneOntologyBiologicalProcessT cell activation involved in immune response

FOXP1 RC3H2 EP300 RC3H1

6.89e-05148314GO:0002286
GeneOntologyBiologicalProcessthyroid hormone receptor signaling pathway

NCOA1 THRA

7.82e-059312GO:0002154
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell activation

FOXP1 RC3H2 EP300 RC3H1

7.84e-05153314GO:0035710
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

NCOA2 FOXP1 EP300 ESR1

8.24e-05155314GO:0043401
GeneOntologyBiologicalProcessrespiratory system development

FOXP1 RC3H2 THRA EP300 NOTCH1

8.48e-05305315GO:0060541
GeneOntologyBiologicalProcessmRNA transcription

NCOA2 NCOA1 THRA

8.51e-0557313GO:0009299
GeneOntologyBiologicalProcessmating behavior

NCOA2 NCOA1 THRA

8.51e-0557313GO:0007617
GeneOntologyBiologicalProcessregulation of T-helper cell differentiation

RC3H2 EP300 RC3H1

8.51e-0557313GO:0045622
GeneOntologyBiologicalProcessalpha-beta T cell differentiation

FOXP1 RC3H2 EP300 RC3H1

8.66e-05157314GO:0046632
GeneOntologyBiologicalProcessresponse to hormone

NCOA2 NCOA1 FOXP1 THRA MN1 EP300 ESR1 NOTCH1

1.15e-041042318GO:0009725
GeneOntologyBiologicalProcessnuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

PATL2 RC3H2 RC3H1

1.26e-0465313GO:0000288
GeneOntologyBiologicalProcessprostate glandular acinus development

ESR1 NOTCH1

1.43e-0412312GO:0060525
GeneOntologyBiologicalProcessconnective tissue development

NCOA2 NCOA1 THRA EP300 NOTCH1

1.47e-04343315GO:0061448
GeneOntologyBiologicalProcessnegative regulation of epithelial cell differentiation

FOXP1 SALL1 NOTCH1

1.51e-0469313GO:0030857
GeneOntologyBiologicalProcessregulation of CD4-positive, alpha-beta T cell differentiation

RC3H2 EP300 RC3H1

1.78e-0473313GO:0043370
GeneOntologyBiologicalProcessreproductive behavior

NCOA2 NCOA1 THRA

1.85e-0474313GO:0019098
GeneOntologyBiologicalProcesspositive regulation of adipose tissue development

NCOA2 NCOA1

1.97e-0414312GO:1904179
GeneOntologyBiologicalProcessnegative regulation of T-helper 17 cell differentiation

RC3H2 RC3H1

1.97e-0414312GO:2000320
GeneOntologyBiologicalProcessregulation of morphogenesis of an epithelium

FOXP1 SALL1 ESR1

2.01e-0476313GO:1905330
GeneOntologyBiologicalProcessnegative regulation of T-helper 17 type immune response

RC3H2 RC3H1

2.27e-0415312GO:2000317
GeneOntologyBiologicalProcessresponse to steroid hormone

NCOA2 NCOA1 FOXP1 EP300 ESR1

2.40e-04381315GO:0048545
GeneOntologyBiologicalProcessregulation of intracellular steroid hormone receptor signaling pathway

NCOA2 FOXP1 EP300

2.99e-0487313GO:0033143
GeneOntologyBiologicalProcessdevelopmental growth

SP2 FOXP1 RC3H2 SALL1 EP300 ESR1 NOTCH1

3.32e-04911317GO:0048589
GeneOntologyBiologicalProcessskeletal muscle tissue development

FOXP1 COL19A1 EP300 NOTCH1

3.33e-04223314GO:0007519
GeneOntologyBiologicalProcessalpha-beta T cell activation

FOXP1 RC3H2 EP300 RC3H1

3.56e-04227314GO:0046631
GeneOntologyBiologicalProcessregulation of alpha-beta T cell differentiation

RC3H2 EP300 RC3H1

3.64e-0493313GO:0046637
GeneOntologyBiologicalProcessregulation of hydrogen peroxide-mediated programmed cell death

FOXP1 EP300

3.68e-0419312GO:1901298
GeneOntologyBiologicalProcessovulation cycle

NCOA1 ESR1 NOTCH1

3.87e-0495313GO:0042698
GeneOntologyBiologicalProcessregulation of cardiac muscle hypertrophy

FOXP1 EP300 NOTCH1

4.12e-0497313GO:0010611
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

NCOA2 FOXP1 EP300 ESR1

4.33e-04239314GO:0071383
GeneOntologyBiologicalProcessskeletal muscle organ development

FOXP1 COL19A1 EP300 NOTCH1

4.39e-04240314GO:0060538
GeneOntologyBiologicalProcessmuscle organ development

FOXP1 ZFHX3 COL19A1 EP300 NOTCH1

4.45e-04436315GO:0007517
GeneOntologyBiologicalProcessregulation of muscle hypertrophy

FOXP1 EP300 NOTCH1

4.50e-04100313GO:0014743
GeneOntologyBiologicalProcessregulation of CD4-positive, alpha-beta T cell activation

RC3H2 EP300 RC3H1

4.50e-04100313GO:2000514
GeneOntologyBiologicalProcessregulation of cardiac muscle tissue growth

FOXP1 EP300 NOTCH1

4.50e-04100313GO:0055021
GeneOntologyBiologicalProcessregulation of adipose tissue development

NCOA2 NCOA1

4.51e-0421312GO:1904177
GeneOntologyBiologicalProcesslocomotor rhythm

NCOA2 ZFHX3

4.96e-0422312GO:0045475
GeneOntologyBiologicalProcesshydrogen peroxide-mediated programmed cell death

FOXP1 EP300

4.96e-0422312GO:0010421
GeneOntologyBiologicalProcessnegative regulation of T-helper cell differentiation

RC3H2 RC3H1

4.96e-0422312GO:0045623
GeneOntologyBiologicalProcessimmune system development

CTNNBL1 FOXP1 RC3H2 RC3H1

4.97e-04248314GO:0002520
GeneOntologyBiologicalProcesslymphocyte activation involved in immune response

FOXP1 RC3H2 EP300 RC3H1

5.20e-04251314GO:0002285
GeneOntologyBiologicalProcessP-body assembly

PATL2 RC3H1

5.42e-0423312GO:0033962
GeneOntologyBiologicalProcessresponse to ketone

NCOA2 NCOA1 FOXP1 EP300

5.44e-04254314GO:1901654
GeneOntologyBiologicalProcessregulation of heart growth

FOXP1 EP300 NOTCH1

5.49e-04107313GO:0060420
GeneOntologyBiologicalProcessregulation of neuron differentiation

NCOA1 ZFHX3 SALL1 NOTCH1

5.52e-04255314GO:0045664
GeneOntologyBiologicalProcessorgan growth

FOXP1 EP300 ESR1 NOTCH1

5.60e-04256314GO:0035265
GeneOntologyBiologicalProcessprogrammed cell death in response to reactive oxygen species

FOXP1 EP300

5.91e-0424312GO:0097468
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell differentiation

RC3H2 RC3H1

6.95e-0426312GO:0043371
GeneOntologyBiologicalProcesspositive regulation of programmed cell death

CTNNBL1 NCOA1 FOXP1 TOMM22 EP300 NOTCH1

7.09e-04739316GO:0043068
GeneOntologyBiologicalProcessperoxisome proliferator activated receptor signaling pathway

NCOA2 NCOA1

8.06e-0428312GO:0035357
GeneOntologyBiologicalProcessregulation of striated muscle cell differentiation

FOXP1 EP300 NOTCH1

8.23e-04123313GO:0051153
GeneOntologyBiologicalProcessnegative regulation of alpha-beta T cell differentiation

RC3H2 RC3H1

9.89e-0431312GO:0046639
GeneOntologyBiologicalProcessregulation of androgen receptor signaling pathway

FOXP1 EP300

9.89e-0431312GO:0060765
GeneOntologyBiologicalProcessdevelopmental growth involved in morphogenesis

SALL1 EP300 ESR1 NOTCH1

1.00e-03299314GO:0060560
GeneOntologyBiologicalProcessembryo development

NCOA1 SUPT20HL1 BPTF SP2 FOXP1 SALL1 EP300 NOTCH1

1.01e-031437318GO:0009790
GeneOntologyBiologicalProcessnuclear-transcribed mRNA catabolic process

PATL2 RC3H2 RC3H1

1.01e-03132313GO:0000956
GeneOntologyBiologicalProcesscardiac cell development

FOXP1 EP300 NOTCH1

1.01e-03132313GO:0055006
GeneOntologyBiologicalProcessregulation of muscle adaptation

FOXP1 EP300 NOTCH1

1.03e-03133313GO:0043502
GeneOntologyBiologicalProcessregulation of glucose metabolic process

NCOA2 SUPT20HL1 EP300

1.05e-03134313GO:0010906
GeneOntologyBiologicalProcesslymph node development

RC3H2 RC3H1

1.12e-0333312GO:0048535
GeneOntologyBiologicalProcessprostate gland epithelium morphogenesis

ESR1 NOTCH1

1.12e-0333312GO:0060740
GeneOntologyBiologicalProcesscardiac muscle tissue growth

FOXP1 EP300 NOTCH1

1.15e-03138313GO:0055017
GeneOntologyBiologicalProcessresponse to lipid

NCOA2 NCOA1 FOXP1 MN1 EP300 ESR1 NOTCH1

1.17e-031126317GO:0033993
GeneOntologyBiologicalProcessnegative regulation of miRNA metabolic process

EP300 ESR1

1.19e-0334312GO:2000629
GeneOntologyBiologicalProcessprostate gland morphogenesis

ESR1 NOTCH1

1.19e-0334312GO:0060512
GeneOntologyCellularComponentchromatin

NCOA2 NCOA1 SUPT20HL1 BPTF SP2 FOXP1 SP4 ZFHX3 PRDM10 THRA SALL1 EP400 EP300 ESR1

6.31e-0914803114GO:0000785
GeneOntologyCellularComponenttranscription regulator complex

NCOA2 NCOA1 ZFHX3 PRDM10 THRA SALL1 EP300 ESR1

1.84e-06596318GO:0005667
GeneOntologyCellularComponenthistone acetyltransferase complex

SUPT20HL1 EP400 EP300

3.61e-0494313GO:0000123
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

BPTF SALL1 EP400

3.84e-0496313GO:0070603
GeneOntologyCellularComponentP-body

PATL2 RC3H2 RC3H1

4.59e-04102313GO:0000932
GeneOntologyCellularComponentprotein acetyltransferase complex

SUPT20HL1 EP400 EP300

4.86e-04104313GO:0031248
GeneOntologyCellularComponentacetyltransferase complex

SUPT20HL1 EP400 EP300

5.57e-04109313GO:1902493
GeneOntologyCellularComponentnuclear protein-containing complex

CTNNBL1 NCOA2 NCOA1 BPTF THRA SALL1 EP400 SCAF8

6.99e-041377318GO:0140513
GeneOntologyCellularComponentATPase complex

BPTF SALL1 EP400

9.09e-04129313GO:1904949
MousePhenolethality during fetal growth through weaning, incomplete penetrance

SP2 FOXP1 RC3H2 SP4 ZFHX3 THRA SALL1 COL19A1 MN1 EP300 MMUT

1.13e-0511243011MP:0011112
MousePhenoabnormal thyroid-stimulating hormone level

NCOA1 ZFHX3 THRA

4.66e-0533303MP:0003971
MousePhenoabnormal response/metabolism to endogenous compounds

NCOA1 THRA ERN1 ESR1

6.83e-05104304MP:0003638
MousePhenoabnormal rete testis morphology

NCOA2 ESR1

1.24e-048302MP:0006416
MousePhenoabnormal left-right axis symmetry of the somites

SUPT20HL1 NOTCH1

1.24e-048302MP:0005224
MousePhenochronic liver inflammation

RC3H1 NOTCH1

1.24e-048302MP:0031301
MousePhenoabnormal small intestinal villus morphology

THRA EP300 RC3H1

1.94e-0453303MP:0008108
MousePhenodecreased areal bone mineral density

THRA ESR1

1.98e-0410302MP:0013618
MousePhenoincreased circulating triiodothyronine level

NCOA1 THRA

2.42e-0411302MP:0005480
MousePhenoincreased triiodothyronine level

NCOA1 THRA

3.42e-0413302MP:0005474
MousePhenoabnormal areal bone mineral density

THRA ESR1

3.99e-0414302MP:0013614
MousePhenoincreased circulating thyroxine level

NCOA1 THRA

4.59e-0415302MP:0005477
MousePhenoreduced male mating frequency

SP4 ESR1

4.59e-0415302MP:0001380
MousePhenoventricle myocardium hypoplasia

FOXP1 EP300 NOTCH1

4.62e-0471303MP:0010502
MousePhenoincreased thyroxine level

NCOA1 THRA

5.24e-0416302MP:0005470
MousePhenosmall heart

FOXP1 THRA EP300 ESR1 NOTCH1

5.50e-04321305MP:0002188
MousePhenoabnormal offspring retrieval

THRA ESR1

5.94e-0417302MP:0009731
MousePhenoincreased circulating thyroid-stimulating hormone level

NCOA1 THRA

5.94e-0417302MP:0005122
MousePhenoabnormal pup retrieval

THRA ESR1

5.94e-0417302MP:0001384
MousePhenochronic inflammation

ESR1 RC3H1 NOTCH1

6.32e-0479303MP:0002499
MousePhenoincreased amino acid level

NCOA1 THRA MMUT

6.32e-0479303MP:0014527
MousePhenoincreased circulating estradiol level

NCOA1 ESR1

6.67e-0418302MP:0005182
MousePhenoincreased circulating levels of thyroid hormone

NCOA1 THRA

7.44e-0419302MP:0003350
MousePhenoincreased circulating estrogen level

NCOA1 ESR1

7.44e-0419302MP:0003370
MousePhenomyocardium hypoplasia

FOXP1 EP300 NOTCH1

8.09e-0486303MP:0010500
MousePhenodecreased compact bone area

THRA ESR1

8.26e-0420302MP:0010968
MousePhenoincreased thyroid-stimulating hormone level

NCOA1 THRA

8.26e-0420302MP:0005135
MousePhenothin ventricle myocardium compact layer

FOXP1 EP300

8.26e-0420302MP:0010556
MousePhenoabnormal nervous system development

NCOA1 SUPT20HL1 SP2 THRA SALL1 EP400 EP300 RC3H1 NOTCH1

9.37e-041257309MP:0003861
DomainNuc_rcpt_coact

NCOA2 NCOA1 EP300

7.45e-086303IPR009110
DomainDUF1518

NCOA2 NCOA1

7.48e-063302PF07469
DomainDUF1518

NCOA2 NCOA1

7.48e-063302IPR010011
DomainSrc1_rcpt_coact

NCOA2 NCOA1

7.48e-063302IPR008955
DomainNuclear_rcpt_coactivator

NCOA2 NCOA1

7.48e-063302IPR017426
DomainDUF1518

NCOA2 NCOA1

7.48e-063302SM01151
DomainNuc_rcpt_coact_Ncoa-typ

NCOA2 NCOA1

7.48e-063302IPR014920
DomainSRC-1

NCOA2 NCOA1

7.48e-063302IPR014935
DomainSRC-1

NCOA2 NCOA1

7.48e-063302PF08832
Domain-

NCOA2 NCOA1

7.48e-0633024.10.630.10
DomainNuc_rec_co-act

NCOA2 NCOA1

7.48e-063302PF08815
DomainSp1_fam

SP2 SP4

1.11e-0410302IPR030450
DomainPAS

NCOA2 NCOA1

7.31e-0425302PF00989
DomainPAS_fold

NCOA2 NCOA1

7.31e-0425302IPR013767
DomainBromodomain_CS

BPTF EP300

7.91e-0426302IPR018359
DomainPAS

NCOA2 NCOA1

1.20e-0332302SM00091
DomainZINC_FINGER_C2H2_2

SP2 FOXP1 SP4 ZFHX3 PRDM10 SALL1

1.27e-03775306PS50157
DomainZINC_FINGER_C2H2_1

SP2 FOXP1 SP4 ZFHX3 PRDM10 SALL1

1.28e-03777306PS00028
DomainPAS

NCOA2 NCOA1

1.36e-0334302IPR000014
DomainZnf-RING_LisH

RC3H2 RC3H1

1.36e-0334302IPR027370
Domainzf-RING_UBOX

RC3H2 RC3H1

1.36e-0334302PF13445
DomainPAS

NCOA2 NCOA1

1.36e-0334302PS50112
DomainZnf_C2H2-like

SP2 FOXP1 SP4 ZFHX3 PRDM10 SALL1

1.45e-03796306IPR015880
DomainZnf_C2H2

SP2 FOXP1 SP4 ZFHX3 PRDM10 SALL1

1.54e-03805306IPR007087
DomainZnF_C2H2

SP2 FOXP1 SP4 ZFHX3 PRDM10 SALL1

1.57e-03808306SM00355
DomainBROMODOMAIN_1

BPTF EP300

1.60e-0337302PS00633
DomainBromodomain

BPTF EP300

1.69e-0338302PF00439
Domain-

RC3H2 RC3H1

1.87e-03403024.10.1000.10
DomainBROMODOMAIN_2

BPTF EP300

1.97e-0341302PS50014
DomainBROMO

BPTF EP300

2.06e-0342302SM00297
DomainBromodomain

BPTF EP300

2.06e-0342302IPR001487
Domain-

BPTF EP300

2.06e-03423021.20.920.10
Domainzf-C4

THRA ESR1

2.47e-0346302PF00105
DomainNUCLEAR_REC_DBD_1

THRA ESR1

2.47e-0346302PS00031
DomainZnf_hrmn_rcpt

THRA ESR1

2.47e-0346302IPR001628
DomainNuclear_hrmn_rcpt

THRA ESR1

2.47e-0346302IPR001723
DomainZnF_C4

THRA ESR1

2.47e-0346302SM00399
DomainNUCLEAR_REC_DBD_2

THRA ESR1

2.47e-0346302PS51030
Domain-

THRA ESR1

2.58e-03473021.10.565.10
DomainZnF_C3H1

RC3H2 RC3H1

2.69e-0348302SM00356
DomainHOLI

THRA ESR1

2.69e-0348302SM00430
DomainNucl_hrmn_rcpt_lig-bd

THRA ESR1

2.69e-0348302IPR000536
DomainHormone_recep

THRA ESR1

2.69e-0348302PF00104
Domainzf-CCCH

RC3H2 RC3H1

2.80e-0349302PF00642
PathwayKEGG_MEDICUS_REFERENCE_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY

NCOA2 NCOA1 ESR1

3.40e-0711193M47503
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

NCOA2 NCOA1 EP300 ESR1

1.33e-0663194MM15613
PathwayPID_ERA_GENOMIC_PATHWAY

NCOA2 NCOA1 EP300 ESR1

1.42e-0664194M200
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

NCOA2 NCOA1 EP300

1.67e-0618193M26942
PathwayPID_SMAD2_3NUCLEAR_PATHWAY

NCOA2 NCOA1 EP300 ESR1

3.86e-0682194M2
PathwayREACTOME_SUMOYLATION

NCOA2 NCOA1 THRA EP300 ESR1

4.10e-06189195M27214
PathwayPID_RETINOIC_ACID_PATHWAY

NCOA2 NCOA1 EP300

8.24e-0630193M207
PathwayBIOCARTA_PELP1_PATHWAY

EP300 ESR1

1.72e-055192MM1575
PathwayKEGG_MEDICUS_VARIANT_ESR1_POSITIVE_TO_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY

NCOA1 ESR1

1.72e-055192M48983
PathwayBIOCARTA_PELP1_PATHWAY

EP300 ESR1

2.57e-056192M22062
PathwayREACTOME_ESR_MEDIATED_SIGNALING

NCOA2 NCOA1 EP300 ESR1

2.63e-05133194MM15529
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

NCOA2 NCOA1 EP300

2.65e-0544193M27295
PathwayREACTOME_HATS_ACETYLATE_HISTONES

NCOA2 NCOA1 EP400 EP300

3.40e-05142194M27233
PathwayPID_HES_HEY_PATHWAY

NCOA1 EP300 NOTCH1

3.46e-0548193M288
PathwayREACTOME_HEME_SIGNALING

NCOA2 NCOA1 EP300

3.68e-0549193M41832
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

NCOA1 SALL1 EP400 EP300 NOTCH1

3.90e-05301195MM15983
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

NCOA2 NCOA1 EP300 ESR1

4.11e-05149194M27888
PathwayPID_AR_TF_PATHWAY

NCOA2 NCOA1 EP300

4.66e-0553193M151
PathwayBIOCARTA_PPARG_PATHWAY

NCOA1 EP300

4.80e-058192M22058
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

EP300 NOTCH1

4.80e-058192M48024
PathwayREACTOME_SUMOYLATION

NCOA1 THRA EP300 ESR1

6.71e-05169194MM14919
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

EP300 NOTCH1

7.70e-0510192MM15535
PathwayPID_HIF1_TFPATHWAY

NCOA2 NCOA1 EP300

9.00e-0566193M255
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

EP300 NOTCH1

9.40e-0511192M48021
PathwayREACTOME_CIRCADIAN_CLOCK

NCOA2 NCOA1 EP300

1.07e-0470193M938
PathwayREACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

NCOA2 NCOA1 EP300 ESR1

1.08e-04191194MM15586
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

NCOA1 EP300

1.33e-0413192MM15622
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3

ZFHX3 EP300 NOTCH1

1.37e-0476193MM15520
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

NCOA2 NCOA1

1.55e-0414192M27074
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

NCOA2 NCOA1

1.55e-0414192MM14748
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

EP300 NOTCH1

1.55e-0414192M27808
PathwayREACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS

NCOA2 NCOA1 EP300 NOTCH1

1.56e-04210194M41836
PathwayPID_REG_GR_PATHWAY

NCOA2 NCOA1 EP300

1.72e-0482193M115
PathwayPID_ERB_GENOMIC_PATHWAY

NCOA2 NCOA1

1.79e-0415192M119
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION

NCOA2 NCOA1 EP300

1.85e-0484193M1008
PathwayREACTOME_ESR_MEDIATED_SIGNALING

NCOA2 NCOA1 EP300 ESR1

1.86e-04220194M27794
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

EP300 NOTCH1

2.04e-0416192M27121
PathwayWP_ANDROGEN_RECEPTOR_SIGNALING

NCOA2 NCOA1 EP300

2.34e-0491193M39700
PathwayREACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS

NCOA2 NCOA1

2.60e-0418192M4862
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

NCOA2 NCOA1

2.60e-0418192MM15034
PathwayREACTOME_SIGNALING_BY_NOTCH1

EP300 NOTCH1

2.60e-0418192MM14775
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3

ZFHX3 EP300 NOTCH1

2.74e-0496193M27784
PathwayREACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS

NCOA2 NCOA1

2.90e-0419192MM14612
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

EP300 NOTCH1

3.22e-0420192M27881
PathwayREACTOME_ADIPOGENESIS

NCOA2 NCOA1 EP300

4.09e-04110193M48259
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

NCOA2 NCOA1 EP400 EP300

4.18e-04272194M29619
PathwayBIOCARTA_HER2_PATHWAY

EP300 ESR1

4.28e-0423192MM1480
PathwayBIOCARTA_HER2_PATHWAY

EP300 ESR1

4.28e-0423192M18719
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

NCOA2 NCOA1

4.28e-0423192M1926
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

NCOA2 NCOA1

4.28e-0423192MM14741
PathwayREACTOME_CELLULAR_RESPONSES_TO_STIMULI

NCOA2 NCOA1 ERN1 EP400 EP300

4.43e-04505195MM15548
PathwayBIOCARTA_VDR_PATHWAY

NCOA1 EP300

4.67e-0424192M13404
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

NCOA2 NCOA1 EP300

5.02e-04118193M27316
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

EP300 NOTCH1

5.07e-0425192M27880
PathwayREACTOME_ENDOGENOUS_STEROLS

NCOA2 NCOA1

5.07e-0425192M11184
PathwayBIOCARTA_CARM_ER_PATHWAY

EP300 ESR1

5.49e-0426192M2499
PathwayPID_RXR_VDR_PATHWAY

NCOA1 THRA

5.49e-0426192M162
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS

EP300 ESR1

5.49e-0426192MM15502
PathwayREACTOME_CELLULAR_RESPONSES_TO_STIMULI

NCOA2 NCOA1 ERN1 EP400 EP300 NOTCH1

5.65e-04828196M27827
PathwayREACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

NCOA2 NCOA1 EP300 ESR1

5.75e-04296194M27869
PathwayREACTOME_ENDOGENOUS_STEROLS

NCOA2 NCOA1

5.92e-0427192MM14844
PathwayREACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION

NCOA2 NCOA1

5.92e-0427192M26943
PathwayREACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS

THRA ESR1

6.37e-0428192MM15042
PathwayWP_NUCLEAR_RECEPTORS_METAPATHWAY

NCOA2 NCOA1 EP300 ESR1

7.18e-04314194M39428
PathwayREACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS

THRA ESR1

7.32e-0430192M27323
PathwayWP_CONSTITUTIVE_ANDROSTANE_RECEPTOR_PATHWAY

NCOA2 NCOA1

7.82e-0431192M39476
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_PLURIPOTENT_STEM_CELLS

FOXP1 SALL1

7.82e-0431192M27393
PathwayWP_PREGNANE_X_RECEPTOR_PATHWAY

NCOA2 NCOA1

8.33e-0432192M39567
PathwayWP_ENDODERM_DIFFERENTIATION

BPTF SP4 NOTCH1

8.79e-04143193M39591
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

NCOA2 NCOA1

8.86e-0433192M5967
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

NCOA2 NCOA1

8.86e-0433192MM14737
PathwayWP_BREAST_CANCER_PATHWAY

NCOA1 ESR1 NOTCH1

1.09e-03154193M39739
PathwayREACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

NCOA1 EP300

1.11e-0337192M29790
PathwayWP_GENETIC_CAUSES_OF_PORTOSINUSOIDAL_VASCULAR_DISEASE

ESR1 NOTCH1

1.11e-0337192M45513
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS

EP300 ESR1

1.18e-0338192M27757
PathwayWP_NUCLEAR_RECEPTORS

THRA ESR1

1.18e-0338192M39657
PathwayWP_NUCLEAR_RECEPTORS

THRA ESR1

1.18e-0338192MM15865
PathwayREACTOME_SIGNALING_BY_NOTCH

EP300 NOTCH1

1.24e-0339192MM14604
PathwayREACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS

NCOA2 NCOA1 EP300

1.26e-03162193MM15688
PathwayPID_FOXM1_PATHWAY

EP300 ESR1

1.30e-0340192M176
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

NCOA1 EP300

1.30e-0340192MM15000
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

EP300 NOTCH1

1.43e-0342192M17541
PathwayREACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP

NCOA2 NCOA1

1.43e-0342192M27172
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

NCOA2 NCOA1

1.57e-0344192M499
PathwayPID_HNF3A_PATHWAY

EP300 ESR1

1.57e-0344192M285
PathwayWP_ARYL_HYDROCARBON_RECEPTOR_PATHWAY_WP2873

NCOA1 EP300

1.65e-0345192M39615
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

NCOA2 NCOA1

1.65e-0345192MM14751
PathwayREACTOME_HATS_ACETYLATE_HISTONES

NCOA2 NCOA1

1.72e-0346192MM14935
PathwayWP_ARYL_HYDROCARBON_RECEPTOR_PATHWAY_WP2586

EP300 ESR1

1.72e-0346192M39661
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

EP300 NOTCH1

1.79e-0347192M7946
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

NCOA1 EP300

1.79e-0347192M29777
PathwayWP_ENERGY_METABOLISM

NCOA1 EP300

1.87e-0348192M39590
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

EP300 NOTCH1

1.87e-0348192M611
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

THRA ESR1

1.87e-0348192MM14987
PathwayREACTOME_SIGNALING_BY_NOTCH3

EP300 NOTCH1

1.95e-0349192M618
PathwayREACTOME_CYTOPROTECTION_BY_HMOX1

NCOA2 NCOA1

2.19e-0352192MM15684
PathwayBIOCARTA_PPARA_PATHWAY

NCOA1 EP300

2.19e-0352192M2404
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

THRA ESR1

2.28e-0353192M8276
PathwayWP_CIRCADIAN_RHYTHM_GENES

NCOA2 ZFHX3 EP300

2.34e-03201193M39605
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS

NCOA2 NCOA1

2.45e-0355192M27145
Pubmed

Ligand-independent interactions of p160/steroid receptor coactivators and CREB-binding protein (CBP) with estrogen receptor-alpha: regulation by phosphorylation sites in the A/B region depends on other receptor domains.

NCOA2 NCOA1 EP300 ESR1

2.58e-12531412714702
Pubmed

Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly.

NCOA2 NCOA1 EP300 ESR1

7.73e-12631416923966
Pubmed

Regulation of glucocorticoid receptor activity by 14--3-3-dependent intracellular relocalization of the corepressor RIP140.

NCOA2 NCOA1 THRA ESR1

3.67e-101331411266503
Pubmed

MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation.

NCOA1 THRA EP300 ESR1

5.14e-101431417641689
Pubmed

Interaction network of human early embryonic transcription factors.

NCOA2 NCOA1 BPTF FOXP1 ZFHX3 SALL1 EP400 EP300

6.40e-1035131838297188
Pubmed

Mediator and p300/CBP-steroid receptor coactivator complexes have distinct roles, but function synergistically, during estrogen receptor alpha-dependent transcription with chromatin templates.

NCOA1 EP300 ESR1

6.41e-10331312482985
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

NCOA2 NCOA1 BPTF SP2 FOXP1 SP4 ZFHX3 THRA SALL1 ESR1

1.24e-09808311020412781
Pubmed

Human transcription factor protein interaction networks.

NCOA2 NCOA1 BPTF SP2 FOXP1 ZFHX3 SALL1 EP400 SCAF8 EP300 ESR1 RC3H1

1.51e-091429311235140242
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NCOA2 NCOA1 SP2 FOXP1 RC3H2 SALL1 EP400 EP300

1.72e-0939831835016035
Pubmed

Analysis of the steroid receptor coactivator 1 (SRC1)-CREB binding protein interaction interface and its importance for the function of SRC1.

NCOA1 EP300 ESR1

2.56e-09431311113179
Pubmed

Transcriptional synergism on the pS2 gene promoter between a p160 coactivator and estrogen receptor-alpha depends on the coactivator subtype, the type of estrogen response element, and the promoter context.

NCOA2 NCOA1 ESR1

2.56e-09431312403846
Pubmed

Reduction of coactivator expression by antisense oligodeoxynucleotides inhibits ERalpha transcriptional activity and MCF-7 proliferation.

NCOA2 NCOA1 ESR1

2.56e-09431311818499
Pubmed

Cyclic changes in the expression of steroid receptor coactivators and corepressors in the normal human endometrium.

NCOA1 EP300 ESR1

2.56e-09431312574227
Pubmed

Unique roles of p160 coactivators for regulation of breast cancer cell proliferation and estrogen receptor-alpha transcriptional activity.

NCOA2 NCOA1 ESR1

2.56e-09431319095746
Pubmed

A simple method to screen ligands of peroxisome proliferator-activated receptor delta.

NCOA2 NCOA1 EP300

2.56e-09431316930961
Pubmed

Isoform-specific transcriptional regulation by thyroid hormone receptors: hormone-independent activation operates through a steroid receptor mode of co-activator interaction.

NCOA2 NCOA1 THRA

2.56e-09431311435616
Pubmed

Conformational changes and coactivator recruitment by novel ligands for estrogen receptor-alpha and estrogen receptor-beta: correlations with biological character and distinct differences among SRC coactivator family members.

NCOA2 NCOA1 ESR1

6.40e-09531311014206
Pubmed

Ligands specify coactivator nuclear receptor (NR) box affinity for estrogen receptor subtypes.

NCOA2 NCOA1 ESR1

6.40e-09531311376110
Pubmed

Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells.

NCOA2 EP300 ESR1

6.40e-09531316645043
Pubmed

SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.

NCOA2 NCOA1 EP300

6.40e-0953139812974
Pubmed

Isoform-selective interactions between estrogen receptors and steroid receptor coactivators promoted by estradiol and ErbB-2 signaling in living cells.

NCOA2 NCOA1 ESR1

6.40e-09531312554772
Pubmed

Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action.

NCOA2 NCOA1 EP300 ESR1

1.04e-082831424880616
Pubmed

Mutual antagonism of estrogen receptors alpha and beta and their preferred interactions with steroid receptor coactivators in human osteoblastic cell lines.

NCOA2 NCOA1 ESR1

1.28e-08631312630920
Pubmed

Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells.

EP300 ESR1 NOTCH1

1.28e-08631319838210
Pubmed

BRCA1-IRIS regulates cyclin D1 expression in breast cancer cells.

NCOA2 NCOA1 ESR1

2.24e-08731316860316
Pubmed

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function.

NCOA2 NCOA1 ESR1

2.24e-0873139192892
Pubmed

Temporal formation of distinct thyroid hormone receptor coactivator complexes in HeLa cells.

NCOA2 NCOA1 THRA

2.24e-08731311117530
Pubmed

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex.

NCOA2 NCOA1 EP300

2.24e-0873139590696
Pubmed

The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine.

NCOA2 NCOA1 EP300

2.24e-08731312709428
Pubmed

Synergistic enhancement of nuclear receptor function by p160 coactivators and two coactivators with protein methyltransferase activities.

NCOA2 NCOA1 ESR1

3.58e-08831311050077
Pubmed

Targeting of SWI/SNF chromatin remodelling complexes to estrogen-responsive genes.

NCOA2 NCOA1 ESR1

3.58e-08831312145209
Pubmed

Different classes of coactivators recognize distinct but overlapping binding sites on the estrogen receptor ligand binding domain.

NCOA2 NCOA1 ESR1

3.58e-0883139774463
Pubmed

The activation function-1 domain of Nur77/NR4A1 mediates trans-activation, cell specificity, and coactivator recruitment.

NCOA2 NCOA1 EP300

3.58e-08831312082103
Pubmed

A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors.

NCOA1 THRA ESR1

3.58e-0883138616895
Pubmed

Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase.

NCOA2 EP300 ESR1

3.58e-08831310490106
Pubmed

A census of human transcription factors: function, expression and evolution.

NCOA1 SP2 FOXP1 RC3H2 SP4 ZFHX3 THRA SALL1 ESR1

6.52e-0890831919274049
Pubmed

Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells.

NCOA1 EP300 ESR1

7.66e-081031312738788
Pubmed

The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor.

NCOA2 NCOA1 ESR1

7.66e-081031317363140
Pubmed

Activating signal cointegrator 1, a novel transcription coactivator of nuclear receptors, and its cytosolic localization under conditions of serum deprivation.

NCOA1 EP300 ESR1

1.05e-071131310454579
Pubmed

Electrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifs.

NCOA2 NCOA1 ESR1

1.05e-071131312612084
Pubmed

Modification of ASC1 by UFM1 is crucial for ERα transactivation and breast cancer development.

NCOA1 EP300 ESR1

1.40e-071231325219498
Pubmed

Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases.

NCOA1 THRA ESR1

1.40e-071231315140878
Pubmed

Multiplexed molecular interactions of nuclear receptors using fluorescent microspheres.

NCOA2 NCOA1 EP300

2.32e-071431311500849
Pubmed

A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo.

NCOA1 THRA ESR1

2.90e-071531310567404
Pubmed

Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

NCOA2 NCOA1 EP300

4.32e-071731319183483
Pubmed

Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase.

NCOA1 EP300 ESR1

6.15e-071931328424251
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

NCOA2 BPTF FOXP1 PRDM10 SALL1 EP400 EP300 NOTCH1

6.28e-0785731825609649
Pubmed

The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription.

NCOA2 NCOA1 ESR1

7.23e-072031316957778
Pubmed

T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.

NCOA2 NCOA1 EP300

7.23e-072031311877444
Pubmed

Synergism between ERalpha transactivation function 1 (AF-1) and AF-2 mediated by steroid receptor coactivator protein-1: requirement for the AF-1 alpha-helical core and for a direct interaction between the N- and C-terminal domains.

NCOA1 ESR1

7.69e-07231211682626
Pubmed

Interaction of steroid receptor coactivators and estrogen receptors in the human placenta.

NCOA2 ESR1

7.69e-07231226733313
Pubmed

A fusion protein of the estrogen receptor (ER) and nuclear receptor corepressor (NCoR) strongly inhibits estrogen-dependent responses in breast cancer cells.

NCOA1 ESR1

7.69e-07231210598586
Pubmed

SRC-1 and TIF2 control energy balance between white and brown adipose tissues.

NCOA2 NCOA1

7.69e-07231212507421
Pubmed

Isoforms of steroid receptor co-activator 1 differ in their ability to potentiate transcription by the oestrogen receptor.

NCOA1 ESR1

7.69e-0723129427757
Pubmed

FOXP1 and estrogen signaling in breast cancer.

FOXP1 ESR1

7.69e-07231223810008
Pubmed

ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response.

ERN1 ESR1

7.69e-07231229451493
Pubmed

Molecular determinants of the estrogen receptor-coactivator interface.

NCOA1 ESR1

7.69e-07231210207113
Pubmed

Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction.

NCOA2 NCOA1

7.69e-07231215070739
Pubmed

Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency.

NCOA2 NCOA1

7.69e-07231211897715
Pubmed

Distinct steady-state nuclear receptor coregulator complexes exist in vivo.

NCOA2 NCOA1

7.69e-0723129751728
Pubmed

Transient estrogen receptor binding and p300 redistribution support a squelching mechanism for estradiol-repressed genes.

EP300 ESR1

7.69e-07231225051172
Pubmed

Molecular mechanism of the inhibition of estradiol-induced endometrial epithelial cell proliferation by clomiphene citrate.

NCOA1 ESR1

7.69e-07231219934375
Pubmed

Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis.

NCOA2 NCOA1

7.69e-07231225148457
Pubmed

Trichostatin A enhances acetylation as well as protein stability of ERalpha through induction of p300 protein.

EP300 ESR1

7.69e-07231220388208
Pubmed

Association of polymorphisms in estrogen and thyroid hormone receptors with thyroid cancer risk.

THRA ESR1

7.69e-07231219519176
Pubmed

Expression of the forkhead transcription factor FOXP1 is associated with estrogen receptor alpha and improved survival in primary human breast carcinomas.

FOXP1 ESR1

7.69e-07231215161711
Pubmed

Detection of ERalpha-SRC-1 interactions using bioluminescent resonance energy transfer.

NCOA1 ESR1

7.69e-07231219763509
Pubmed

Synergy between estrogen receptor alpha activation functions AF1 and AF2 mediated by transcription intermediary factor TIF2.

NCOA2 ESR1

7.69e-07231211265755
Pubmed

Interaction of transcriptional intermediary factor 2 nuclear receptor box peptides with the coactivator binding site of estrogen receptor alpha.

NCOA2 ESR1

7.69e-07231211937504
Pubmed

Tumor necrosis factor-alpha suppresses the expression of steroid receptor coactivator-1 and -2: a possible mechanism contributing to changes in steroid hormone responsiveness.

NCOA2 NCOA1

7.69e-07231215231721
Pubmed

Structure of human Roquin-2 and its complex with constitutive-decay element RNA.

RC3H2 RC3H1

7.69e-07231226249698
Pubmed

Estrogen up-regulates ATBF1 transcription but causes its protein degradation in estrogen receptor-alpha-positive breast cancer cells.

ZFHX3 ESR1

7.69e-07231221367855
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

NCOA2 NCOA1 EP300

8.44e-072131319596656
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

NCOA2 BPTF EP400 EP300

9.03e-078331428794006
Pubmed

The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro.

NCOA1 EP300 ESR1

9.76e-072231311867769
Pubmed

BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

EP300 ESR1

2.31e-06331219887647
Pubmed

Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse.

NCOA2 NCOA1

2.31e-06331216914740
Pubmed

Estrogen receptor alpha represses transcription of early target genes via p300 and CtBP1.

EP300 ESR1

2.31e-06331219188451
Pubmed

Absence of the steroid receptor coactivator-3 induces B-cell lymphoma.

NCOA2 NCOA1

2.31e-06331216675958
Pubmed

Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation.

RC3H2 RC3H1

2.31e-06331223583642
Pubmed

Specific Knockout of Notch-1 in Macrophages Modulate the Progression of Hepatic Insulin Resistance in HFD Fed Mice via Regulating IRE1α-XBP1 Signals.

ERN1 NOTCH1

2.31e-06331238720211
Pubmed

GAS, a new glutamate-rich protein, interacts differentially with SRCs and is involved in oestrogen receptor function.

NCOA1 ESR1

2.31e-06331219039327
Pubmed

Roquin Paralogs Differentially Regulate Functional NKT Cell Subsets.

RC3H2 RC3H1

2.31e-06331228188245
Pubmed

Specificity of thyroid hormone receptor subtype and steroid receptor coactivator-1 on thyroid hormone action.

NCOA1 THRA

2.31e-06331212388168
Pubmed

Steroid receptor coactivator 2 is essential for progesterone-dependent uterine function and mammary morphogenesis: insights from the mouse--implications for the human.

NCOA2 NCOA1

2.31e-06331217045797
Pubmed

The MN1 oncoprotein synergizes with coactivators RAC3 and p300 in RAR-RXR-mediated transcription.

MN1 EP300

2.31e-06331212569362
Pubmed

ERAP75 functions as a coactivator to enhance estrogen receptor alpha transactivation in prostate stromal cells.

NCOA1 ESR1

2.31e-06331218563714
Pubmed

Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a.

NCOA1 EP300

2.31e-06331211773079
Pubmed

Recurrent MEIS1-NCOA2/1 fusions in a subset of low-grade spindle cell sarcomas frequently involving the genitourinary and gynecologic tracts.

NCOA2 NCOA1

2.31e-06331233574497
Pubmed

Identification of BAF57 mutations in human breast cancer cell lines.

NCOA1 ESR1

2.31e-06331216538531
Pubmed

The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.

NCOA2 NCOA1

2.31e-06331212138202
Pubmed

Inhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivators.

NCOA2 NCOA1

2.31e-06331212114525
Pubmed

p300 acts as a transcriptional coactivator for mammalian Notch-1.

EP300 NOTCH1

2.31e-06331211604511
Pubmed

Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.

RC3H2 RC3H1

2.31e-06331225026077
Pubmed

Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice.

NCOA2 NCOA1

2.31e-06331215983373
Pubmed

p300/cAMP-response-element-binding-protein ('CREB')-binding protein (CBP) modulates co-operation between myocyte enhancer factor 2A (MEF2A) and thyroid hormone receptor-retinoid X receptor.

THRA EP300

2.31e-06331212371907
Pubmed

The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles.

NCOA2 NCOA1

2.31e-06331221035760
Pubmed

Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors.

NCOA2 NCOA1

2.31e-06331224550004
Pubmed

Distinctive functions of p160 steroid receptor coactivators in proliferation of an estrogen-independent, tamoxifen-resistant breast cancer cell line.

NCOA2 NCOA1

2.31e-06331221059860
Pubmed

RORgammat recruits steroid receptor coactivators to ensure thymocyte survival.

NCOA2 NCOA1

2.31e-06331216148126
InteractionCRX interactions

NCOA2 NCOA1 FOXP1 SP4 ZFHX3 SALL1 EP400 EP300

3.50e-09254318int:CRX
InteractionFEV interactions

NCOA2 SP2 FOXP1 ZFHX3 SALL1 EP400 EP300

2.03e-08203317int:FEV
InteractionNR2F1 interactions

NCOA2 NCOA1 FOXP1 THRA ESR1

2.66e-0858315int:NR2F1
InteractionTLE3 interactions

NCOA2 NCOA1 ZFHX3 SALL1 SCAF8 EP300 ESR1 NOTCH1

7.39e-08376318int:TLE3
InteractionMED23 interactions

CTNNBL1 NCOA2 ZFHX3 EP400 EP300 ESR1 NOTCH1

1.29e-07266317int:MED23
InteractionSOX7 interactions

NCOA2 NCOA1 FOXP1 SALL1 EP300

1.54e-0782315int:SOX7
InteractionHNF4A interactions

NCOA2 NCOA1 BPTF FOXP1 EP400 EP300 ESR1

1.62e-07275317int:HNF4A
InteractionPGR interactions

NCOA2 NCOA1 BPTF EP300 ESR1

1.74e-0784315int:PGR
InteractionMAZ interactions

BPTF RC3H2 EP300 ESR1 RC3H1

1.96e-0786315int:MAZ
InteractionEGR2 interactions

NCOA2 NCOA1 FOXP1 ZFHX3 EP400 EP300

2.11e-07171316int:EGR2
InteractionTEAD1 interactions

NCOA1 BPTF FOXP1 ZFHX3 SALL1 EP300

2.50e-07176316int:TEAD1
InteractionSF1 interactions

CTNNBL1 NCOA1 RC3H2 EP300 MMUT ESR1 RC3H1

3.20e-07304317int:SF1
InteractionKCTD5 interactions

RC3H2 MN1 EP300 ESR1 RC3H1

3.58e-0797315int:KCTD5
InteractionHNF1B interactions

NCOA2 BPTF FOXP1 ZFHX3 EP400 EP300

3.93e-07190316int:HNF1B
InteractionMYOD1 interactions

NCOA2 NCOA1 BPTF EP400 EP300 ESR1

4.44e-07194316int:MYOD1
InteractionPDIA6 interactions

BPTF RC3H2 SGTB ERN1 EP300 ESR1 RC3H1

5.23e-07327317int:PDIA6
InteractionTHRA interactions

NCOA2 NCOA1 THRA EP300 ESR1

7.02e-07111315int:THRA
InteractionSELENOP interactions

THRA EP400 EP300

7.18e-0712313int:SELENOP
InteractionNCOA3 interactions

NCOA2 NCOA1 THRA MN1 EP300 ESR1

1.03e-06224316int:NCOA3
InteractionNCOA2 interactions

NCOA2 NCOA1 THRA EP300 ESR1

2.29e-06141315int:NCOA2
InteractionNCOA6 interactions

NCOA2 NCOA1 THRA EP300 ESR1

2.63e-06145315int:NCOA6
InteractionNCOA1 interactions

NCOA2 NCOA1 THRA EP300 ESR1

2.72e-06146315int:NCOA1
InteractionMTA1 interactions

BPTF FOXP1 SALL1 SGTB EP300 ESR1

3.99e-06283316int:MTA1
InteractionKLF15 interactions

NCOA2 NCOA1 SP2 EP400 EP300 MMUT

4.59e-06290316int:KLF15
InteractionRXRA interactions

NCOA2 NCOA1 THRA EP300 ESR1

5.57e-06169315int:RXRA
InteractionSP7 interactions

NCOA2 NCOA1 FOXP1 EP400 SCAF8 EP300

6.01e-06304316int:SP7
InteractionTLX1 interactions

NCOA2 FOXP1 ZFHX3 SALL1 EP300

6.60e-06175315int:TLX1
InteractionANIB1 interactions

NCOA1 ESR1

6.86e-063312int:ANIB1
InteractionXRCC6 interactions

BPTF RC3H2 ZFHX3 THRA EP400 EP300 ESR1 RC3H1 NOTCH1

7.22e-06928319int:XRCC6
InteractionSMG7 interactions

NCOA2 NCOA1 RC3H2 SALL1 SCAF8 RC3H1

7.91e-06319316int:SMG7
InteractionALG13 interactions

NCOA2 RC3H2 SCAF8 EP300 RC3H1

8.20e-06183315int:ALG13
InteractionTHRB interactions

NCOA2 NCOA1 THRA EP300 ESR1

8.87e-06186315int:THRB
InteractionZCCHC9 interactions

CTNNBL1 RC3H2 ESR1 RC3H1

8.91e-0686314int:ZCCHC9
InteractionGSC interactions

FOXP1 ZFHX3 SALL1 EP300

9.33e-0687314int:GSC
InteractionGOLGA2 interactions

NCOA2 FOXP1 ZFHX3 SALL1 SCAF8 EP300 ESR1 NOTCH1

1.11e-05733318int:GOLGA2
InteractionKLF5 interactions

NCOA2 FOXP1 EP400 EP300 ESR1

1.12e-05195315int:KLF5
InteractionC19orf53 interactions

RC3H2 ESR1 RC3H1

1.17e-0529313int:C19orf53
InteractionPIAS3 interactions

NCOA2 ZFHX3 EP300 ESR1

1.32e-0595314int:PIAS3
InteractionNR1H4 interactions

NCOA1 EP300 ESR1

1.59e-0532313int:NR1H4
InteractionPAX6 interactions

BPTF FOXP1 ZFHX3 SALL1 EP400 EP300

1.73e-05366316int:PAX6
InteractionPLRG1 interactions

CTNNBL1 RC3H2 EP300 ESR1 RC3H1

1.83e-05216315int:PLRG1
InteractionNFIX interactions

BPTF FOXP1 ZFHX3 SALL1 EP400

2.32e-05227315int:NFIX
InteractionKLF3 interactions

BPTF FOXP1 ZFHX3 EP400 EP300

2.37e-05228315int:KLF3
InteractionCNOT9 interactions

RC3H2 SALL1 SCAF8 ESR1 RC3H1

2.52e-05231315int:CNOT9
InteractionFHL2 interactions

SP2 FOXP1 SP4 EP400 EP300 ESR1

2.69e-05396316int:FHL2
InteractionRORA interactions

NCOA2 NCOA1 EP300

2.90e-0539313int:RORA
InteractionSP2 interactions

SP2 RC3H2 ESR1

2.90e-0539313int:SP2
InteractionELK3 interactions

SP2 FOXP1 SP4 EP400

3.32e-05120314int:ELK3
InteractionGATAD2B interactions

BPTF FOXP1 SALL1 ESR1 NOTCH1

3.35e-05245315int:GATAD2B
InteractionTFF1 interactions

SGTB EP300 ESR1

3.38e-0541313int:TFF1
InteractionNR5A2 interactions

NCOA2 NCOA1 ESR1

3.38e-0541313int:NR5A2
InteractionETS1 interactions

NCOA1 BPTF EP400 EP300

3.43e-05121314int:ETS1
InteractionDDX17 interactions

FOXP1 RC3H2 EP300 ESR1 RC3H1 NOTCH1

4.05e-05426316int:DDX17
InteractionSNRNP40 interactions

CTNNBL1 RC3H2 ZFHX3 PRDM10 EP400 SCAF8 RC3H1

4.14e-05637317int:SNRNP40
InteractionC11orf98 interactions

RC3H2 ESR1 RC3H1

4.18e-0544313int:C11orf98
InteractionPAX9 interactions

NCOA2 FOXP1 ZFHX3 EP300

4.54e-05130314int:PAX9
InteractionPTBP1 interactions

FOXP1 RC3H2 EP300 ESR1 RC3H1 NOTCH1

4.67e-05437316int:PTBP1
InteractionAHR interactions

NCOA2 NCOA1 EP300 ESR1

4.82e-05132314int:AHR
InteractionPYM1 interactions

RC3H2 EP300 ESR1 RC3H1

4.97e-05133314int:PYM1
InteractionKIF11 interactions

RC3H2 MN1 EP300 ESR1 RC3H1

5.04e-05267315int:KIF11
InteractionSMAD3 interactions

NCOA1 BPTF ZFHX3 EP300 ESR1 NOTCH1

5.29e-05447316int:SMAD3
InteractionPPP2R1A interactions

CTNNBL1 RC3H2 TOMM22 EP400 EP300 ESR1 NOTCH1

5.44e-05665317int:PPP2R1A
InteractionNR1I3 interactions

NCOA2 NCOA1 ESR1

5.44e-0548313int:NR1I3
InteractionNR1I2 interactions

NCOA2 NCOA1 EP300

5.44e-0548313int:NR1I2
InteractionPRPF19 interactions

CTNNBL1 RC3H2 EP300 ESR1 RC3H1 NOTCH1

5.49e-05450316int:PRPF19
InteractionRBM27 interactions

RC3H2 EP300 ESR1 RC3H1

5.58e-05137314int:RBM27
InteractionGTF2B interactions

NCOA1 THRA EP300 ESR1

6.24e-05141314int:GTF2B
InteractionSMARCA4 interactions

NCOA1 BPTF EP400 EP300 ESR1 NOTCH1

6.36e-05462316int:SMARCA4
InteractionWDR11 interactions

FOXP1 EP300 ESR1 NOTCH1

6.77e-05144314int:WDR11
InteractionNKX3-1 interactions

SP2 SP4 ESR1

6.92e-0552313int:NKX3-1
InteractionSUMO1 interactions

NCOA2 NCOA1 SALL1 EP300 ESR1

7.10e-05287315int:SUMO1
InteractionPCBP2 interactions

FOXP1 RC3H2 EP300 ESR1 RC3H1

7.21e-05288315int:PCBP2
InteractionPURA interactions

FOXP1 RC3H2 EP300 ESR1 RC3H1

7.57e-05291315int:PURA
InteractionTLX3 interactions

NCOA2 FOXP1 ZFHX3 SALL1 EP300

7.57e-05291315int:TLX3
InteractionMEF2C interactions

NCOA2 EP300 NOTCH1

7.75e-0554313int:MEF2C
InteractionCIITA interactions

NCOA1 EP400 EP300

8.19e-0555313int:CIITA
InteractionEIF3F interactions

RC3H2 EP300 ESR1 RC3H1 NOTCH1

8.21e-05296315int:EIF3F
InteractionBCL3 interactions

NCOA1 EP300 ESR1

8.64e-0556313int:BCL3
InteractionSRSF4 interactions

BPTF RC3H2 PRDM10 EP300 RC3H1

8.74e-05300315int:SRSF4
InteractionSNRPA1 interactions

FOXP1 RC3H2 TOMM22 EP300 RC3H1

8.74e-05300315int:SNRPA1
InteractionPURB interactions

RC3H2 EP300 ESR1 RC3H1

9.24e-05156314int:PURB
InteractionSRSF6 interactions

BPTF RC3H2 PRDM10 EP300 ESR1 RC3H1

1.02e-04503316int:SRSF6
InteractionWBP11 interactions

CTNNBL1 FOXP1 RC3H2 EP300

1.02e-04160314int:WBP11
InteractionFOS interactions

NCOA2 NCOA1 EP400 EP300 ESR1

1.05e-04312315int:FOS
InteractionRBBP7 interactions

BPTF SALL1 EP400 EP300 ESR1 RC3H1

1.06e-04507316int:RBBP7
InteractionANAPC7 interactions

MN1 EP300 ESR1 NOTCH1

1.07e-04162314int:ANAPC7
InteractionPHF6 interactions

RC3H2 EP300 ESR1 RC3H1

1.07e-04162314int:PHF6
InteractionDDX55 interactions

RC3H2 EP300 ESR1 RC3H1

1.26e-04169314int:DDX55
InteractionMRM3 interactions

RC3H2 EP300 ESR1 RC3H1

1.26e-04169314int:MRM3
InteractionNRIP1 interactions

NCOA2 NCOA1 THRA ESR1

1.29e-04170314int:NRIP1
InteractionKLF8 interactions

NCOA2 BPTF FOXP1 EP400 EP300

1.35e-04329315int:KLF8
InteractionPRP4K interactions

CTNNBL1 RC3H2 EP300 ESR1 RC3H1

1.35e-04329315int:PRP4K
InteractionPOU2F1 interactions

SP4 ZFHX3 THRA ESR1

1.44e-04175314int:POU2F1
InteractionSLBP interactions

RC3H2 EP300 RC3H1

1.48e-0467313int:SLBP
InteractionESRRA interactions

NCOA2 NCOA1 ESR1

1.48e-0467313int:ESRRA
InteractionCNOT2 interactions

RC3H2 ZFHX3 ESR1 RC3H1

1.54e-04178314int:CNOT2
InteractionLEF1 interactions

EP300 ESR1 NOTCH1

1.61e-0469313int:LEF1
InteractionTDG interactions

THRA EP300 ESR1

1.61e-0469313int:TDG
InteractionSNRPD1 interactions

FOXP1 RC3H2 EP300 ESR1 RC3H1

1.73e-04347315int:SNRPD1
InteractionASCC1 interactions

NCOA1 EP300 ESR1

1.75e-0471313int:ASCC1
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA2 NCOA1 EP300

1.21e-0617233486
GeneFamilyZinc fingers C2H2-type|Sp transcription factors

SP2 SP4

5.54e-059232755
GeneFamilyZinc fingers CCCH-type

RC3H2 RC3H1

8.98e-043523273
GeneFamilyNuclear hormone receptors

THRA ESR1

1.76e-034923271
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

SP2 SP4 ZFHX3 PRDM10 SALL1

1.81e-0371823528
GeneFamilyBasic helix-loop-helix proteins

NCOA2 NCOA1

8.54e-03110232420
CoexpressionGSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN

CDS1 COL19A1 MN1 ESR1 RC3H1 NOTCH1

1.12e-07199316M6987
CoexpressionLAKE_ADULT_KIDNEY_C11_THIN_ASCENDING_LIMB

NCOA2 SAMD12 NCOA1 FOXP1 NEK10

1.56e-06169315M39230
CoexpressionGSE7831_1H_VS_4H_INFLUENZA_STIM_PDC_DN

CDS1 COL19A1 MN1 RC3H1 NOTCH1

3.47e-06199315M6964
CoexpressionGSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP

NCOA1 BPTF RC3H2 ZFHX3 NOTCH1

3.56e-06200315M7256
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

BPTF PRDM10 ERN1 EP300

5.85e-05180314M8239
CoexpressionMYLLYKANGAS_AMPLIFICATION_HOT_SPOT_22

MN1 EP300

7.40e-0511312M11594
CoexpressionGSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_UP

NCOA1 RC3H2 SP4 SCAF8

8.81e-05200314M3614
CoexpressionGSE10240_CTRL_VS_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP

CDS1 ERN1 ESR1 RC3H1

8.81e-05200314M302
CoexpressionTABULA_MURIS_SENIS_MESENTERIC_ADIPOSE_TISSUE_MESENCHYMAL_STEM_CELL_OF_ADIPOSE_AGEING

BPTF FOXP1 ZFHX3 TOMM22 EP400 MN1

1.31e-04685316MM3782
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

BPTF FOXP1 SALL1 MN1 NOTCH1

2.49e-07199315358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

NCOA2 SAMD12 NCOA1 COL19A1

1.00e-05196314ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

NCOA2 SAMD12 NCOA1 COL19A1

1.04e-051983141996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellCOVID-19_Moderate-B_cell|World / disease group, cell group and cell class

FCRL2 PATL2 SP4

1.22e-04139313b93e1da87d44e55d75e8cc1b87c2970645679c01
ToppCellCOVID-19_Moderate-B_cell|COVID-19_Moderate / disease group, cell group and cell class

FCRL2 PATL2 SP4

1.30e-0414231388bb8d9bca66131df4ee7021b88248e146aa7aa6
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Tregs|GI_small-bowel / Manually curated celltypes from each tissue

FOXP1 SGTB NEK10

1.68e-04155313d4ef25965a15eab7679478b9b661e1b4a92f1c59
ToppCellfacs-Marrow-T-cells-24m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRDM10 CDCP1 ESR1

1.84e-04160313b3f7ef7e682b48a83ca425f5c439336e96168300
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCRL2 ERN1 ESR1

1.91e-041623138ed9149ff53b285591354057055d072b203a47c8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCRL2 ERN1 ESR1

1.91e-041623137a05b05a33e1309fb5c0a8171db105ae68491815
ToppCell5'-Adult-Appendix-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCRL2 ERN1 ESR1

2.02e-0416531379c6ad394266ff092029375883660028e944a3c8
ToppCellVE-Treg-exh_CD4|VE / Condition, Cell_class and T cell subcluster

RC3H2 SGTB NEK10

2.09e-041673131036ac1ef9440612500137af9d1929672b077e4d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX3 COL19A1 NOTCH1

2.17e-041693131c9e54e7b14eb99996590fb93b257cf881a9f184
ToppCellAdult-Immune-B_cell-D175|Adult / Lineage, Cell type, age group and donor

FCRL2 COL19A1 ESR1

2.24e-04171313355a246f3395900342d400f6f7c6640cba0d4d5d
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 FOXP1 COL19A1

2.28e-0417231362ed3b70fa1f6c84ea80ff00f60d2562be292e9d
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 MN1 NEK10

2.36e-0417431359ccc5a82507463e0a316ba6286cb25ec1a4091b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFHX3 CDCP1 NOTCH1

2.48e-0417731362f180d5a487b449f715de49ee1e1e11c4e0cf4d
ToppCellE12.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FOXP1 MN1 NOTCH1

2.48e-041773135cdf413f82376a95467322b16d10b0d1e7557e2d
ToppCellB_cells-Naive_B_cells_|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

FCRL2 FOXP1 COL19A1

2.52e-0417831371ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCellControl-Lymphocyte-B-B_naive|Control / Disease, Lineage and Cell Type

FCRL2 FOXP1 COL19A1

2.56e-0417931335994281904bfe38766e715ab608211a5ca865a9
ToppCellCOVID-19_Mild-NK_CD56bright|COVID-19_Mild / Disease condition and Cell class

ZFHX3 CDCP1 NOTCH1

2.56e-0417931390e7a4af195aa2332b07a9f06cde63e72ff49255
ToppCellLeuk-UTI-Lymphocyte-B-B_naive|Leuk-UTI / Disease, Lineage and Cell Type

FCRL2 FOXP1 COL19A1

2.65e-04181313fb0b5a94796b99c64091f9890f7a09c39bbc3f73
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FCRL2 ERN1 ESR1

2.65e-041813136cdee2f56bc633b387b4dbbd78c624edbd712c24
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FCRL2 ERN1 ESR1

2.65e-04181313b75b8b025257bccfe661fd0f92ab284b2a9c12ee
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-8|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 FOXP1 COL19A1

2.65e-04181313ca34d83daca10c5fa52ecdf4eba7d31b4e7e056e
ToppCellInfluenza_Severe-B_naive|World / Disease group and Cell class

FCRL2 FOXP1 COL19A1

2.69e-04182313e4885a5e6065c9c403cb2d305228691d6ae4ecb6
ToppCellwk_20-22-Mesenchymal-Chondrocyte-intermediate_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ZFHX3 SGTB MN1

2.74e-041833131464b5c4425e8776c4aeb4d2b560481d4bf13931
ToppCellCOVID-19-B_cells|COVID-19 / group, cell type (main and fine annotations)

FCRL2 ERN1 ESR1

2.74e-041833132c016bb59f131a0e821853b085289a3583f0a729
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SAMD12 FOXP1 SGTB

2.78e-04184313bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCellBac-SEP-Lymphocyte-B-B_naive|Bac-SEP / Disease, Lineage and Cell Type

FCRL2 FOXP1 COL19A1

2.82e-041853134d9e1eeb353c0b1f82f557856e99c8bf04aa2a7f
ToppCellControl-Lymphocyte-B|Control / Disease, Lineage and Cell Type

FCRL2 FOXP1 COL19A1

2.82e-04185313cb61b5ff6a2ef71c94469c35cafc21df5bcf61b1
ToppCellURO-Lymphocyte-B|URO / Disease, Lineage and Cell Type

FCRL2 FOXP1 COL19A1

2.87e-04186313c46ff4fc280b67a454ee9614e93c6854a5a400b8
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

NCOA2 PRDM10 EP300

2.87e-0418631303db813598b67b1e08f759758a1c2023396921fa
ToppCell10x5'-Liver-Lymphocytic_B-Naive_B_cells|Liver / Manually curated celltypes from each tissue

FCRL2 FOXP1 COL19A1

2.87e-0418631323efdcedbe67f5e6c59106e052f570cd0338f1c1
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-8|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 FOXP1 COL19A1

2.92e-04187313c10d6a774b3e83f64e47b9ad08f5d6b0dc60d163
ToppCellURO-Lymphocyte-B-B_naive|URO / Disease, Lineage and Cell Type

FCRL2 FOXP1 COL19A1

2.92e-041873139ed6a39aae7126ddbd01aec3376113b6b4517383
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-B_lymphocytic-naive_B_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FCRL2 FOXP1 COL19A1

2.92e-04187313160e5f338537d90d50f863a1be801b1071ac7da7
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDS1 ERN1 CDCP1

2.96e-041883134bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellfacs-Heart-RA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP1 SALL1 NOTCH1

2.96e-041883134ddb11a90bf3baa7237bde304db44dfcc56aed52
ToppCell10x5'-blood-Lymphocytic_B-Naive_B_cells|blood / Manually curated celltypes from each tissue

FCRL2 FOXP1 COL19A1

2.96e-041883132b3560b28f9df6f4d4a3e0a4acfa6c7d964ad0fe
ToppCellfacs-Heart-RA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP1 SALL1 NOTCH1

2.96e-04188313e47e66906922d5c69b1aafe28face0787d3fc563
ToppCellP07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SAMD12 FOXP1 NOTCH1

2.96e-041883135bc1537e079c7435196c163bff5f639ea392a33a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCRL2 FOXP1 COL19A1

2.96e-04188313d8decd9b5967873ca8320c2f9f07365f163c777f
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

FCRL2 ERN1 ESR1

2.96e-04188313567b08514d9d84cbb40f9b7a679eec304f023428
ToppCellHealthy-B_naive|World / disease group, cell group and cell class

FCRL2 FOXP1 COL19A1

3.01e-041893131e533a43f739ff295740cf2b25479756dfb8e595
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAMD12 MN1 NOTCH1

3.01e-0418931392319bef1f00d6048ba8f9f8b5c6dbb896686b74
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FCRL2 FOXP1 COL19A1

3.05e-04190313a7498fe55b7810c482291db782dc5282675d246a
ToppCellSevere-MAIT|World / Disease group and Cell class

SAMD12 THRA ERN1

3.05e-041903137a92e0d6a021be23125495927b8571e25c83204a
ToppCellsevere-B_naive|World / disease stage, cell group and cell class

FCRL2 FOXP1 COL19A1

3.05e-041903138dfe067d75573289299a5fba42b6c9b26e5fb430
ToppCellsevere-B_naive|severe / disease stage, cell group and cell class

FCRL2 FOXP1 COL19A1

3.05e-041903132430a1fd18385305bf1b604747ff64026a8d5edf
ToppCellSevere-MAIT|Severe / Disease group and Cell class

SAMD12 THRA ERN1

3.05e-041903131c063dc1b62d9f9912aaf8d0297555a6545f5550
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_activate-7|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 FOXP1 COL19A1

3.10e-041913132feab42ac6d29fa4eac78f3f78a5f8aa0a559523
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-B_lymphocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FCRL2 FOXP1 COL19A1

3.10e-041913133fc16e986aff5e0cd4f831e25e78a5b30beba7a8
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-naive_B_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FCRL2 BPTF COL19A1

3.10e-04191313a073d58154c801ec499fd969f42b7f1ee7f15d79
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SAMD12 FOXP1 NOTCH1

3.10e-04191313b270c3dd5952f56b9bdceabe13e298fe6757563b
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 FOXP1 COL19A1

3.10e-041913135a9a592875fbd0b1429b48db29a760fdc9c2c856
ToppCellICU-SEP-Lymphocyte-B-B_naive|ICU-SEP / Disease, Lineage and Cell Type

FCRL2 FOXP1 COL19A1

3.10e-04191313a090f9ea58a700c995c4ad35eeebb699f07040f7
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 FOXP1 COL19A1

3.10e-04191313b7d17d3ba488378b30f3732f8109f4a7c1673e61
ToppCellfacs-Kidney-nan-18m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAMD12 ZFHX3 NOTCH1

3.15e-04192313777e386a17bba9ec450bb9d64d8a9ab98d9a63ff
ToppCellfacs-Kidney-nan-18m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAMD12 ZFHX3 NOTCH1

3.15e-0419231360a2409546525a40a5658e0f9d6a50c37f28bb96
ToppCell10x5'-bone_marrow-Lymphocytic_B-Naive_B_cells|bone_marrow / Manually curated celltypes from each tissue

FCRL2 FOXP1 COL19A1

3.15e-04192313fa99243ff028498c6a67d207a93e02c48e69cd42
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 FOXP1 COL19A1

3.15e-0419231389b8ebdc285ed3c0f807fd1157271130d37dfa41
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 FOXP1 COL19A1

3.15e-04192313ef86d82e4f04f9f54e821ef496d70fc81072d773
ToppCellHealthy/Control-B_intermediate|World / Disease group and Cell class

FCRL2 FOXP1 COL19A1

3.15e-041923132266aa695955f5d885708e6bc0d5a8827c306223
ToppCellfacs-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAMD12 ZFHX3 NOTCH1

3.15e-041923130f9db6091b373334b9beabe0e5782bf2bc54690b
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FCRL2 FOXP1 COL19A1

3.15e-04192313800edadd1d1ba6b7e0a0398030dd4b61c9c480c7
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-9|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 FOXP1 COL19A1

3.20e-04193313d5d188a314da1b4c8390276d88173c09dd7ce4bf
ToppCellsevere_influenza-B_naive|World / disease group, cell group and cell class (v2)

FCRL2 FOXP1 COL19A1

3.20e-04193313c52ba94782ad57b93d20f853a89344dffa8351f9
ToppCelldroplet-Heart-HEART-1m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP1 SALL1 NOTCH1

3.20e-04193313d0a5f212f8e8a13dbbe3e41df92548ef82eef70b
ToppCellControl-NK_CD56bright|Control / Disease condition and Cell class

ZFHX3 CDCP1 NOTCH1

3.20e-041933138b1e7a226a6057e1097c1525984127b54e823876
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_naive-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

FCRL2 FOXP1 COL19A1

3.20e-0419331395ec708d963e9411e2dcf65650ae71a26e9d0e7f
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

FCRL2 FOXP1 COL19A1

3.20e-04193313d0d0835304647758e6ad4348402a4f76a76137a0
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SAMD12 FOXP1 NOTCH1

3.20e-0419331358c590dd6f21bc7ae58ae1729dd574c0f1069592
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCRL2 FOXP1 COL19A1

3.20e-04193313ac227ddabfb3f021b1b39dba73f898517cd5a58e
ToppCellCOVID_non-vent-Lymphocytic-B_cell-|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

FCRL2 FOXP1 COL19A1

3.20e-0419331391955c3773c9729a96e82f240f06b072367970d9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCRL2 FOXP1 COL19A1

3.20e-04193313f4135615ee0118eec9e221becdd67888e0c2a112
ToppCellCOVID_non-vent-Lymphocytic-B_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

FCRL2 FOXP1 COL19A1

3.20e-0419331332d139f922cd19adc1cc1e0e9a828115be9945d6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCRL2 FOXP1 COL19A1

3.25e-041943135cd72330c9d9bb21b6c9d5d35085eade101486d1
ToppCellsevere_influenza-B_naive|severe_influenza / disease group, cell group and cell class (v2)

FCRL2 FOXP1 COL19A1

3.25e-041943137c1e9ce5de3bb1657a67010de673c8bb60129cb6
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 FOXP1 COL19A1

3.25e-04194313e9c907b8ec4329946338cca5ce8e954fa2cec37b
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 FOXP1 COL19A1

3.25e-0419431324f9de4781666c96c4a2d04f8a444543dbd99cbe
ToppCellCOVID-19_Moderate-B_naive|World / disease group, cell group and cell class

FCRL2 FOXP1 COL19A1

3.25e-041943131f81d618799e482a36dce528bba70f52cc69a901
ToppCellControl-Lymphoid_B-B_naive|Control / Disease group, lineage and cell class

FCRL2 FOXP1 COL19A1

3.25e-041943134f9600960a287cfc020c06b4af3528d4e5797916
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FCRL2 BPTF COL19A1

3.25e-04194313ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellCOVID-19_Severe-B_naive|World / disease group, cell group and cell class

FCRL2 FOXP1 COL19A1

3.25e-04194313d363963a6caeedf4f9e9ad22dcf9b66b85c79a48
ToppCellCV-Severe-6|Severe / Virus stimulation, Condition and Cluster

NCOA1 PATL2 FOXP1

3.25e-04194313d33be6ed1de907aeea0c2dce09796556b8efdd4e
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 FOXP1 COL19A1

3.25e-0419431336ce99b9e4e1c968cc7ae381168124cc7c14afb2
ToppCellCOVID-19_Moderate-B_naive|COVID-19_Moderate / disease group, cell group and cell class

FCRL2 FOXP1 COL19A1

3.25e-041943138c41a37467bfd4966ecd09dde68c543dc01b6ad0
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 FOXP1 COL19A1

3.25e-0419431382753b90ca3b563275c41b6040ebbcd99b185e24
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL2 FOXP1 COL19A1

3.25e-04194313287439c51528d7bb13bd235875d85631dc91ed91
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

FCRL2 FOXP1 COL19A1

3.30e-04195313e830f0c545be87a1056a4505bdf6845e5ac7750d
ToppCellInfluenza_Severe-B_naive|Influenza_Severe / Disease group and Cell class

FCRL2 FOXP1 COL19A1

3.30e-04195313a25516ed670c7738670ffbaa6f7cd167946f3825
ToppCellCV-Severe-6|CV / Virus stimulation, Condition and Cluster

NCOA1 PATL2 FOXP1

3.30e-0419531369095c6ce2a7e763afa543c10d5710e0c3dda769
ToppCellHealthy_donor-B_naive|World / disease group, cell group and cell class (v2)

FCRL2 FOXP1 COL19A1

3.30e-04195313c66bbfdf0091cc62aa50edfa88820bbda191b7bb
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FCRL2 FOXP1 COL19A1

3.30e-041953134b882a71f0e02fef5580e9d9bc42245cf9df2e57
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

FCRL2 FOXP1 COL19A1

3.30e-04195313b74645072a063732d5be43036ce0e9568eff3d14
ToppCellmild_COVID-19_(asymptomatic)-B_naive|World / disease group, cell group and cell class (v2)

FCRL2 FOXP1 COL19A1

3.30e-04195313e763d9a431052c03cc6d514f2736506c6667e2be
ToppCellsevere_COVID-19-B_naive|World / disease group, cell group and cell class (v2)

FCRL2 FOXP1 COL19A1

3.30e-04195313e6c77119494b787c44502c0390fb2c86a34b1846
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP1 SALL1 NOTCH1

3.30e-04195313df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCell10x5'-bone_marrow-Lymphocytic_B|bone_marrow / Manually curated celltypes from each tissue

FCRL2 FOXP1 COL19A1

3.30e-04195313bcbf0305ca9337a6f3021178dbb47a7fbf1030a4
ToppCellCOVID-19_Severe-Lymphoid_B-B_naive|COVID-19_Severe / Disease group, lineage and cell class

FCRL2 FOXP1 COL19A1

3.30e-0419531371563e838fcda34a9a209c5433e0d84420373402
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

NCOA2 BPTF ZFHX3 PRDM10 SCAF8 EP300 ESR1

2.01e-091703071050_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA

NCOA2 BPTF ZFHX3 PRDM10 SCAF8 EP300 ESR1

2.18e-091723071072_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA

NCOA2 BPTF ZFHX3 PRDM10 SCAF8 EP300 ESR1

2.46e-091753071058_DN
Drug2',3',4',5'-tetrachloro-4-biphenylol

NCOA2 NCOA1 ESR1

4.12e-086303ctd:C104006
DrugAC1L9M2J

NCOA2 NCOA1 THRA EP300 ESR1

4.84e-0876305CID000448538
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

NCOA2 BPTF ZFHX3 PRDM10 SCAF8 ESR1

1.07e-071783061112_DN
DrugAndrostenols

NCOA2 NCOA1 ESR1

4.51e-0712303ctd:D000737
Drugbicalutamide

NCOA2 NCOA1 FOXP1 EP300 ESR1

5.88e-07125305CID000002375
Drugferutinin

NCOA2 NCOA1 ESR1

1.14e-0616303CID000354654
Drugbis(4-oxyphenyl)sulfide

THRA ESR1

1.68e-062302ctd:C069693
DrugPhosphites

NCOA2 ESR1

1.68e-062302ctd:D017905
Druggalangin

NCOA2 NCOA1 EP300 ESR1

1.88e-0668304ctd:C037032
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 BPTF PRDM10 SCAF8 ESR1

2.18e-061633057453_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 BPTF PRDM10 EP300 ESR1

2.32e-061653055625_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 BPTF ZFHX3 PRDM10 ESR1

2.32e-061653052835_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 BPTF ZFHX3 PRDM10 ESR1

2.38e-061663052247_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

NCOA2 BPTF PRDM10 EP300 ESR1

2.60e-061693055231_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

NCOA2 ZFHX3 PRDM10 EP300 ESR1

2.68e-061703057043_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 BPTF ZFHX3 PRDM10 ESR1

2.84e-061723052330_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 BPTF PRDM10 EP300 ESR1

2.92e-061733052881_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

NCOA2 BPTF PRDM10 SCAF8 EP300

2.92e-061733055950_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 BPTF PRDM10 SCAF8 ESR1

3.00e-061743055693_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

NCOA2 PRDM10 SCAF8 EP300 ESR1

3.09e-061753055935_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA

NCOA2 BPTF PRDM10 EP300 ESR1

3.09e-061753051014_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 BPTF ZFHX3 PRDM10 ESR1

3.18e-061763053312_DN
Drugtrichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA

NCOA2 BPTF ZFHX3 PRDM10 ESR1

3.18e-06176305981_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 BPTF PRDM10 SCAF8 ESR1

3.18e-061763056932_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

NCOA2 BPTF ZFHX3 EP300 ESR1

3.27e-061773056434_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

NCOA2 BPTF PRDM10 SCAF8 EP300

3.45e-061793056609_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 BPTF ZFHX3 PRDM10 ESR1

3.55e-061803056454_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

NCOA2 PRDM10 SCAF8 EP300 ESR1

3.64e-061813056951_DN
DrugDiethylstilbestrol

NCOA2 NCOA1 FCRL2 ZFHX3 THRA ERN1 CDCP1 EP300 ESR1 NOTCH1

3.86e-0613053010ctd:D004054
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A

NCOA2 BPTF PRDM10 SCAF8 ESR1

3.95e-061843056939_DN
Drugholotoxin A1

NCOA2 ESR1

5.03e-063302CID000119551
Drug2-propylpentanoic acid; Down 200; 1000uM; MCF7; HG-U133A

BPTF PRDM10 SCAF8 EP300 ESR1

5.65e-0619830523_DN
Drugtetrac

NCOA1 THRA EP300

7.37e-0629303CID000065552
DrugCV-1

NCOA2 NCOA1 THRA EP300 ESR1

8.05e-06213305CID000130105
DrugAC1L9FY1

NCOA2 NCOA1 EP400 EP300

9.15e-06101304CID000444218
Drugterics

NCOA2 ESR1

1.01e-054302ctd:C021754
DrugMDL 28564

NCOA2 ESR1

1.01e-054302CID000180453
DrugAC1L9K70

NCOA2 NCOA1 THRA EP300 ESR1

1.12e-05228305CID000446871
DrugPhysalemin

SP2 SP4 MMUT

1.31e-0535303CID000017268
Drugempenthrin

NCOA2 ESR1

1.67e-055302CID006434488
Drugdioxybenzone

NCOA2 ESR1

1.67e-055302ctd:C004839
DrugMF101 extract

NCOA2 ESR1

1.67e-055302ctd:C517398
Drug3-benzylidene camphor

NCOA1 ESR1

1.67e-055302ctd:C511303
Drug4-ethoxymethylphenol

NCOA1 ESR1

1.67e-055302CID000093781
DrugAC1ND2OB

NCOA2 NCOA1 THRA EP300 ESR1

2.31e-05265305CID004568637
Drug8-oxyguanine

BPTF EP300 MMUT ESR1

2.48e-05130304CID000119315
Drugbutamben

NCOA2 NCOA1

2.51e-056302ctd:C004605
Drughydroxypropyl methacrylate

CDS1 ESR1

2.51e-056302CID000034023
Drugtegaserod

THRA ESR1

2.51e-056302ctd:C105050
Drugsilyl

SP2 SALL1 MMUT

2.82e-0545303CID000139580
DrugEpirubicin

NCOA2 THRA ESR1

3.22e-0547303ctd:D015251
Drugtb-E

NCOA1 SP4 SALL1

3.22e-0547303CID000006588
Drug4,4'-hexafluorisopropylidene diphenol

NCOA2 NCOA1 THRA ESR1

3.50e-05142304ctd:C583074
Drug1H,1H,2H,2H-perfluorooctan-1-ol

NCOA2 ESR1

3.51e-057302CID000069537
Drugestratriene

CDS1 ESR1

3.51e-057302CID000150899
Drugcilnidipine

NCOA2 ESR1

3.51e-057302ctd:C065927
Drug8:2 FTOH

NCOA2 ESR1

3.51e-057302CID000069619
Druglacidipine

NCOA2 ESR1

3.51e-057302ctd:C060285
DrugL-T3-PAL

CTNNBL1 THRA

3.51e-057302CID005487638
Drugselamectin

NCOA2 ESR1

3.51e-057302ctd:C414354
DrugAC1O5TPK

NCOA2 NCOA1 ESR1

4.12e-0551303CID006440511
DrugN-desmethyl-tamoxifen-hydrochloride

NCOA2 NCOA1 ESR1

4.37e-0552303CID000035887
DrugAC1L2E0P

NCOA2 NCOA1 THRA EP300 ESR1

4.66e-05307305CID000019390
Drug1H,1H,2H,2H-perfluorooctan-1-ol

NCOA2 ESR1

4.68e-058302ctd:C508406
Drugormeloxifene

NCOA1 ESR1

4.68e-058302ctd:C508548
DrugLY 353381

NCOA1 ESR1

4.68e-058302ctd:C115121
DrugMethyltestosterone

NCOA1 ERN1 ESR1

4.89e-0554303ctd:D008777
Drugpregna-4,17-diene-3,16-dione

NCOA2 NCOA1 ESR1

5.17e-0555303ctd:C023617
Drugtris(chloroethyl)phosphate

NCOA2 NCOA1 ESR1

5.17e-0555303ctd:C031324
DrugA25618

NCOA2 NCOA1 FOXP1 THRA SALL1 EP300 ESR1

5.38e-05777307CID000005562
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 ZFHX3 PRDM10 ESR1

5.72e-051613044768_DN
Drug4-phenylphenol

NCOA2 ESR1

6.01e-059302ctd:C019046
Drug2-acetyltributylcitrate

NCOA2 NCOA1

6.01e-059302ctd:C014953
DrugAF-5

EP300 ESR1

6.01e-059302CID005463920
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 BPTF PRDM10 ESR1

6.44e-051663047324_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 BPTF PRDM10 ESR1

6.44e-051663042268_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A

NCOA2 PRDM10 SCAF8 ESR1

6.59e-051673045217_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 PRDM10 EP300 ESR1

6.75e-051683043868_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 BPTF PRDM10 ESR1

6.75e-051683046820_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 BPTF PRDM10 ESR1

6.91e-051693046064_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

NCOA2 BPTF PRDM10 SCAF8

7.07e-051703043791_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA

NCOA2 PRDM10 EP300 ESR1

7.23e-051713041000_DN
Drugirinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A

NCOA2 NCOA1 BPTF SCAF8

7.23e-051713047535_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

ZFHX3 PRDM10 EP300 ESR1

7.23e-051713046879_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 ZFHX3 PRDM10 ESR1

7.39e-051723047179_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 PRDM10 SCAF8 ESR1

7.39e-051723043428_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 PRDM10 EP300 ESR1

7.39e-051723042794_DN
Drugiclaprim

NCOA2 NCOA1 EP300

7.41e-0562303CID000213043
DrugValinomycin

THRA ESR1

7.50e-0510302ctd:D014634
DrugSP 0

SP2 SP4

7.50e-0510302CID002742752
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

NCOA2 BPTF PRDM10 SCAF8

7.56e-051733044665_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 PRDM10 EP300 ESR1

7.56e-051733045987_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 PRDM10 SCAF8 ESR1

7.56e-051733045336_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 ZFHX3 PRDM10 ESR1

7.56e-051733043243_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

NCOA2 PRDM10 SCAF8 ESR1

7.73e-051743046579_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

NCOA2 PRDM10 EP300 ESR1

7.73e-051743045745_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

NCOA2 PRDM10 EP300 ESR1

7.73e-051743041659_DN
Diseasebreast carcinoma (is_marker_for)

NCOA1 ZFHX3 EP300 ESR1

6.86e-0766314DOID:3459 (is_marker_for)
Diseasecongenital heart disease (is_implicated_in)

FOXP1 SP4 NOTCH1

2.09e-0624313DOID:1682 (is_implicated_in)
Diseasethyroid hormone resistance syndrome (implicated_via_orthology)

NCOA1 THRA

3.20e-063312DOID:11633 (implicated_via_orthology)
Diseaselung adenocarcinoma (biomarker_via_orthology)

FOXP1 NOTCH1

6.40e-064312DOID:3910 (biomarker_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of breast

EP300 ESR1 NOTCH1

1.09e-0541313C0496956
DiseaseBreast adenocarcinoma

EP300 ESR1 NOTCH1

1.09e-0541313C0858252
DiseaseBladder Neoplasm

BPTF EP300 ESR1 NOTCH1

1.38e-05140314C0005695
DiseaseMalignant neoplasm of urinary bladder

BPTF EP300 ESR1 NOTCH1

1.42e-05141314C0005684
Diseaseprostate cancer (is_marker_for)

NCOA2 NCOA1 EP300 ESR1

2.12e-05156314DOID:10283 (is_marker_for)
DiseaseCongenital Abnormality

SALL1 NOTCH1

5.84e-0511312C0000768
DiseaseObesity

ZFHX3 EP300 MMUT ESR1

6.15e-05205314C0028754
Diseaseobesity (implicated_via_orthology)

NCOA1 ZFHX3 ESR1 NOTCH1

7.39e-05215314DOID:9970 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

NCOA2 NCOA1 CDS1 COL19A1 EP300 ESR1 NOTCH1

1.01e-041074317C0006142
Diseasehepatoblastoma (is_marker_for)

ZFHX3 SALL1

1.11e-0415312DOID:687 (is_marker_for)
DiseaseUterine leiomyoma, estrogen-receptor positive breast cancer

NEK10 ESR1

1.62e-0418312EFO_1000649, HP_0000131
DiseaseBRCAX breast cancer

CTNNBL1 ESR1

2.01e-0420312EFO_0009443
DiseaseMammary Carcinoma, Human

NCOA2 NCOA1 EP300 ESR1 NOTCH1

2.03e-04525315C4704874
DiseaseMammary Neoplasms, Human

NCOA2 NCOA1 EP300 ESR1 NOTCH1

2.03e-04525315C1257931
DiseaseMammary Neoplasms

NCOA2 NCOA1 EP300 ESR1 NOTCH1

2.06e-04527315C1458155
DiseaseBreast Carcinoma

NCOA2 NCOA1 EP300 ESR1 NOTCH1

2.27e-04538315C0678222
DiseaseCerebral Astrocytoma

ESR1 NOTCH1

3.16e-0425312C0750935
DiseaseIntracranial Astrocytoma

ESR1 NOTCH1

3.16e-0425312C0750936
DiseasePilocytic Astrocytoma

ESR1 NOTCH1

3.16e-0425312C0334583
DiseaseAstrocytoma

ESR1 NOTCH1

3.16e-0425312C0004114
DiseaseJuvenile Pilocytic Astrocytoma

ESR1 NOTCH1

3.16e-0425312C0280783
DiseaseDiffuse Astrocytoma

ESR1 NOTCH1

3.16e-0425312C0280785
DiseaseGrade I Astrocytoma

ESR1 NOTCH1

3.16e-0425312C1704230
DiseaseSubependymal Giant Cell Astrocytoma

ESR1 NOTCH1

3.16e-0425312C0205768
DiseaseMixed oligoastrocytoma

ESR1 NOTCH1

3.16e-0425312C0547065
DiseaseChildhood Cerebral Astrocytoma

ESR1 NOTCH1

3.16e-0425312C0338070
DiseaseGemistocytic astrocytoma

ESR1 NOTCH1

3.42e-0426312C0334581
DiseaseProtoplasmic astrocytoma

ESR1 NOTCH1

3.42e-0426312C0334580
DiseaseFibrillary Astrocytoma

ESR1 NOTCH1

3.42e-0426312C0334582
DiseaseAnaplastic astrocytoma

ESR1 NOTCH1

3.69e-0427312C0334579
Diseaselung non-small cell carcinoma (is_implicated_in)

NCOA2 ZFHX3 ESR1

4.17e-04139313DOID:3908 (is_implicated_in)
Diseasesuicidal ideation

NCOA2 ZFHX3

4.26e-0429312EFO_0004320
DiseaseMammary Neoplasms, Experimental

NCOA1 CDS1 ESR1

5.74e-04155313C0024668
Diseasebreast cancer, ovarian carcinoma

FOXP1 ESR1

6.95e-0437312EFO_0001075, MONDO_0007254
Diseasesystemic lupus erythematosus (implicated_via_orthology)

EP300 RC3H1

9.39e-0443312DOID:9074 (implicated_via_orthology)
Diseasebreast cancer (is_marker_for)

ZFHX3 THRA ESR1

9.58e-04185313DOID:1612 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
QQQQVLSILHANPQL

EP300

2066

Q09472
ITPAHFQLLRQQQQQ

EP400

2746

Q96L91
VLQQLLVLQPEQQLN

CDS1

426

Q92903
ANVPQIRQRVHQILN

CTNNBL1

506

Q8WYA6
LRLQFQVLVQHPQNE

CDCP1

326

Q9H5V8
VPQLQQQVQVLSQIQ

BPTF

2561

Q12830
RTVTELILQHQNPQQ

RC3H2

161

Q9HBD1
VTELILQHQNPQQLS

RC3H1

166

Q5TC82
QPHLVQTQQVQPQNL

NOTCH1

2376

P46531
RQISDPIQQILIQLH

NEK10

1026

Q6ZWH5
TLQQQHQRLAQLLLI

ESR1

496

P03372
LQQQVLSPQQLQVLL

FOXP1

116

Q9H334
LQQPQHIQLQVVQVA

PRDM10

936

Q9NQV6
LTQLHPRHQRILQQQ

PATL2

151

C9JE40
IQLLQQQQQQLPFHP

ERN1

486

O75460
QVLNQQNIPQISIVV

COL19A1

121

Q14993
LQSQIHVQRIPISNV

FCRL2

191

Q96LA5
NLEHLRQQLLEQQQP

SCAF8

311

Q9UPN6
LQQQQIHQLQLIEQI

SALL1

236

Q9NSC2
HPLEILQAQIQLQRQ

MN1

1151

Q10571
LQNVQLQAVNPTQVL

SP4

441

Q02446
QQQPQHIQLQTQQLR

SUPT20HL1

751

Q3ZLR7
HIQLQTQQLRVLQQP

SUPT20HL1

756

Q3ZLR7
TQQLRVLQQPQHIQL

SUPT20HL1

761

Q3ZLR7
VLQQPQHIQLQTQQL

SUPT20HL1

766

Q3ZLR7
QHIQLQTQQLRVLQQ

SUPT20HL1

771

Q3ZLR7
LQLQQRLQGQQQLIH

NCOA1

1056

Q15788
QENLRQHILQQVLQL

SAMD12

126

Q8N8I0
LVQNQPNQLRLQLQH

NCOA2

1181

Q15596
PNQLRLQLQHRLQAQ

NCOA2

1186

Q15596
LQLQHRLQAQQNRQP

NCOA2

1191

Q15596
QQVVQIPQQALRVVQ

SP2

311

Q02086
QQQLQQRQILLGPNT

TOMM22

111

Q9NS69
IQQQNPELIEQLRNH

SGTB

276

Q96EQ0
HVVQGPQVRQLEQQL

THRA

406

P10827
HQQILPQQQQNQLSI

ZFHX3

1846

Q15911
RLIQQRLLHQQQPLH

MMUT

26

P22033