Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	peptide lactyltransferase (CoA-dependent) activity	CREBBP EP300	5.19e-06	2	46	2	GO:0120300
GeneOntologyMolecularFunction	histone H3K27 acetyltransferase activity	CREBBP EP300	5.19e-06	2	46	2	GO:0044017
GeneOntologyMolecularFunction	histone H3K18 acetyltransferase activity	CREBBP EP300	1.56e-05	3	46	2	GO:0043993
GeneOntologyMolecularFunction	bHLH transcription factor binding	SOX9 CREBBP EP300	8.42e-05	37	46	3	GO:0043425
GeneOntologyMolecularFunction	pre-mRNA intronic binding	SOX9 EP300	4.64e-04	14	46	2	GO:0097157
GeneOntologyMolecularFunction	histone H3 acetyltransferase activity	CREBBP EP300	5.35e-04	15	46	2	GO:0010484
GeneOntologyMolecularFunction	peroxisome proliferator activated receptor binding	CREBBP EP300	1.06e-03	21	46	2	GO:0042975
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	KCNMA1 GRIA3	1.39e-03	24	46	2	GO:0099507
GeneOntologyMolecularFunction	chromatin binding	SOX9 ARID1A CREBBP UBTF EP300 SVEP1 L3MBTL4	1.41e-03	739	46	7	GO:0003682
GeneOntologyMolecularFunction	phosphatidylinositol phospholipase C activity	CHRM5 PLCE1	1.63e-03	26	46	2	GO:0004435
GeneOntologyMolecularFunction	phospholipase C activity	CHRM5 PLCE1	2.03e-03	29	46	2	GO:0004629
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	SOX9 DACT1 ARID1A CREBBP HSPA4 EP300	2.08e-03	582	46	6	GO:0140297
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	DACT1 ARID1A CREBBP HSPA4 EP300	2.63e-03	417	46	5	GO:0061629
GeneOntologyMolecularFunction	beta-catenin binding	SOX9 DACT1 EP300	2.66e-03	120	46	3	GO:0008013
GeneOntologyBiologicalProcess	regulation of beta-catenin-TCF complex assembly	SOX9 DACT1	4.65e-06	2	45	2	GO:1904863
GeneOntologyBiologicalProcess	negative regulation of beta-catenin-TCF complex assembly	SOX9 DACT1	4.65e-06	2	45	2	GO:1904864
GeneOntologyBiologicalProcess	beta-catenin-TCF complex assembly	SOX9 DACT1	1.39e-05	3	45	2	GO:1904837
GeneOntologyBiologicalProcess	N-terminal peptidyl-lysine acetylation	CREBBP EP300	2.78e-05	4	45	2	GO:0018076
GeneOntologyCellularComponent	postsynaptic membrane	RNF10 KCNMA1 GPR156 GRIA3 NETO2 CHRM5	2.48e-04	405	46	6	GO:0045211
HumanPheno	Absent earlobe	ZNF407 CREBBP PLK4 EP300	6.45e-07	20	19	4	HP:0000387
HumanPheno	Plantar crease between first and second toes	CREBBP EP300	1.32e-05	2	19	2	HP:0008107
HumanPheno	Aortic isthmus hypoplasia	CREBBP EP300	1.32e-05	2	19	2	HP:0034227
HumanPheno	High axial triradius	CREBBP EP300	1.32e-05	2	19	2	HP:0001042
HumanPheno	Aplasia/Hypoplasia of the earlobes	ZNF407 CREBBP PLK4 EP300	3.61e-05	53	19	4	HP:0009906
HumanPheno	Laryngeal cartilage malformation	CREBBP EP300	3.95e-05	3	19	2	HP:0008752
HumanPheno	Phobia	CREBBP EP300	3.95e-05	3	19	2	HP:5200232
HumanPheno	Agoraphobia	CREBBP EP300	3.95e-05	3	19	2	HP:0000756
HumanPheno	Humoral immunodeficiency	CREBBP EP300	3.95e-05	3	19	2	HP:0005363
HumanPheno	Prominent nasal septum	CREBBP EP300	3.95e-05	3	19	2	HP:0005322
HumanPheno	Radial deviation of thumb terminal phalanx	CREBBP EP300	3.95e-05	3	19	2	HP:0005895
HumanPheno	Abnormal incisor morphology	KCNMA1 GRIA3 CREBBP EP300	6.73e-05	62	19	4	HP:0011063
HumanPheno	Trichiasis	CREBBP EP300	7.87e-05	4	19	2	HP:0001128
HumanPheno	Visceral hemangioma	CREBBP EP300	7.87e-05	4	19	2	HP:0410266
HumanPheno	Talon cusp	CREBBP EP300	7.87e-05	4	19	2	HP:0011087
HumanPheno	Widened distal phalanges	CREBBP EP300	7.87e-05	4	19	2	HP:0006200
HumanPheno	Vascular ring	CREBBP EP300	7.87e-05	4	19	2	HP:0010775
HumanPheno	Hepatic hemangioma	CREBBP EP300	7.87e-05	4	19	2	HP:0031207
HumanPheno	Broad hallux phalanx	DACT1 CREBBP EP300	8.48e-05	24	19	3	HP:0010059
HumanPheno	Shawl scrotum	SAMD9 CREBBP EP300	9.61e-05	25	19	3	HP:0000049
HumanPheno	Abnormal earlobe morphology	GRIA3 ZNF407 CREBBP PLK4 EP300	1.12e-04	137	19	5	HP:0000363
HumanPheno	Papillary cystadenoma of the epididymis	CREBBP EP300	1.31e-04	5	19	2	HP:0009715
HumanPheno	Supernumerary cusp	CREBBP EP300	1.31e-04	5	19	2	HP:0033777
HumanPheno	Epididymal neoplasm	CREBBP EP300	1.31e-04	5	19	2	HP:0030421
HumanPheno	Abnormal scrotum morphology	SOX9 DACT1 SAMD9 CREBBP EP300	1.38e-04	143	19	5	HP:0000045
HumanPheno	Hypoplastic iliac wing	SOX9 CREBBP EP300	1.85e-04	31	19	3	HP:0002866
HumanPheno	Large foramen magnum	CREBBP EP300	1.96e-04	6	19	2	HP:0002700
HumanPheno	Laryngomalacia	KCNMA1 SOX9 CREBBP EP300	2.21e-04	84	19	4	HP:0001601
HumanPheno	Deviated nasal septum	CREBBP EP300	2.74e-04	7	19	2	HP:0004411
HumanPheno	Accessory spleen	RPGRIP1 CREBBP EP300	3.16e-04	37	19	3	HP:0001747
HumanPheno	Sandal gap	ARID1A CREBBP PLK4 EP300	3.70e-04	96	19	4	HP:0001852
HumanPheno	Pilomatrixoma	CREBBP EP300	4.67e-04	9	19	2	HP:0030434
HumanPheno	Cervical cord compression	CREBBP EP300	4.67e-04	9	19	2	HP:0002341
HumanPheno	Abnormality of the incisor	KCNMA1 GRIA3 CREBBP EP300	5.79e-04	108	19	4	HP:0000676
HumanPheno	Frontal hirsutism	CREBBP EP300	5.83e-04	10	19	2	HP:0011335
HumanPheno	Abnormal hallux phalanx morphology	DACT1 CREBBP EP300	6.04e-04	46	19	3	HP:0010057
HumanPheno	Prominent fingertip pads	ZNF407 CREBBP EP300	6.04e-04	46	19	3	HP:0001212
HumanPheno	Broad phalanx of the toes	DACT1 CREBBP EP300	6.43e-04	47	19	3	HP:0010174
HumanPheno	Prominent digit pad	ZNF407 CREBBP EP300	6.85e-04	48	19	3	HP:0011298
HumanPheno	Abnormal subclavian artery morphology	CREBBP EP300	7.11e-04	11	19	2	HP:0031251
HumanPheno	Deviation of toes	SOX9 DACT1 CREBBP EP300	8.10e-04	118	19	4	HP:0100498
HumanPheno	Self-mutilation	GRIA3 CREBBP EP300	8.18e-04	51	19	3	HP:0000742
HumanPheno	Abnormal proximal phalanx morphology of the hand	SOX9 CREBBP EP300	8.66e-04	52	19	3	HP:0009834
HumanPheno	Cryptorchidism	SOX9 RPGRIP1 DACT1 GRIA3 SAMD9 ARID1A CREBBP EP300 BRWD3	9.58e-04	780	19	9	HP:0000028
HumanPheno	Abnormality of the urethra	SOX9 RPGRIP1 DACT1 SAMD9 ARID1A CREBBP EP300	9.61e-04	465	19	7	HP:0000795
HumanPheno	Dislocated radial head	SOX9 CREBBP EP300	9.68e-04	54	19	3	HP:0003083
HumanPheno	Facial grimacing	CREBBP EP300	1.00e-03	13	19	2	HP:0000273
HumanPheno	Macrodontia of permanent maxillary central incisor	KCNMA1 GRIA3	1.00e-03	13	19	2	HP:0000675
HumanPheno	Keloids	CREBBP EP300	1.00e-03	13	19	2	HP:0010562
HumanPheno	Blepharophimosis	SOX9 DACT1 CREBBP EP300	1.13e-03	129	19	4	HP:0000581
HumanPheno	Abnormality of the radial head	SOX9 CREBBP EP300	1.13e-03	57	19	3	HP:0003995
HumanPheno	Abnormal toe phalanx morphology	SOX9 DACT1 CREBBP EP300	1.17e-03	130	19	4	HP:0010161
HumanPheno	Duplication of phalanx of hallux	CREBBP EP300	1.17e-03	14	19	2	HP:0010066
HumanPheno	Hypoplastic aortic arch	CREBBP EP300	1.17e-03	14	19	2	HP:0012304
HumanPheno	Parietal foramina	CREBBP EP300	1.17e-03	14	19	2	HP:0002697
HumanPheno	Cerebellar malformation	DAB1 RPGRIP1 DACT1 GRIA3 ARID1A CREBBP EP300	1.27e-03	487	19	7	HP:0002438
HumanPheno	Duplication of phalanx of toe	CREBBP EP300	1.34e-03	15	19	2	HP:0010181
HumanPheno	Social and occupational deterioration	CREBBP EP300	1.34e-03	15	19	2	HP:0007086
HumanPheno	Unsteady gait	DAB1 RPGRIP1 GRIA3 ARID1A CREBBP EP300	1.41e-03	357	19	6	HP:0002317
HumanPheno	Recurrent upper respiratory tract infections	SOX9 CASP8 ARID1A CREBBP EP300	1.42e-03	237	19	5	HP:0002788
HumanPheno	Abnormality of the humeroradial joint	SOX9 CREBBP EP300	1.45e-03	62	19	3	HP:0100744
HumanPheno	Hypoplastic ilia	SOX9 CREBBP EP300	1.52e-03	63	19	3	HP:0000946
HumanPheno	Incisor macrodontia	KCNMA1 GRIA3	1.53e-03	16	19	2	HP:0011081
HumanPheno	Square face	CREBBP EP300	1.53e-03	16	19	2	HP:0000321
HumanPheno	Neoplasm of the liver	CASP8 ARID1A CREBBP EP300	1.54e-03	140	19	4	HP:0002896
HumanPheno	Pes planus	SOX9 DACT1 GRIA3 CREBBP EP300 BRWD3	1.58e-03	365	19	6	HP:0001763
HumanPheno	Premature thelarche	CREBBP EP300	1.73e-03	17	19	2	HP:0010314
HumanPheno	Abnormal nasopharynx morphology	SOX9 CASP8 ARID1A CREBBP EP300	1.77e-03	249	19	5	HP:0001739
HumanPheno	Hypospadias	SOX9 DACT1 SAMD9 ARID1A CREBBP EP300	1.87e-03	377	19	6	HP:0000047
HumanPheno	Abnormal iliac wing morphology	SOX9 CREBBP EP300	1.89e-03	68	19	3	HP:0011867
HumanPheno	Facial hirsutism	CREBBP EP300	1.95e-03	18	19	2	HP:0009937
HumanPheno	Skin appendage neoplasm	CREBBP EP300	1.95e-03	18	19	2	HP:0012842
HumanPheno	Abnormal pharynx morphology	SOX9 CASP8 ARID1A CREBBP EP300	2.15e-03	260	19	5	HP:0033151
Domain	Nuc_rcpt_coact_CREBbp	CREBBP EP300	5.18e-06	2	43	2	IPR014744
Domain	HAT_KAT11	CREBBP EP300	5.18e-06	2	43	2	PF08214
Domain	KIX	CREBBP EP300	5.18e-06	2	43	2	PS50952
Domain	ZnF_TAZ	CREBBP EP300	5.18e-06	2	43	2	SM00551
Domain	CBP_P300_HAT	CREBBP EP300	5.18e-06	2	43	2	IPR031162
Domain	DUF902	CREBBP EP300	5.18e-06	2	43	2	PF06001
Domain	-	CREBBP EP300	5.18e-06	2	43	2	1.20.1020.10
Domain	RING_CBP-p300	CREBBP EP300	5.18e-06	2	43	2	IPR010303
Domain	-	CREBBP EP300	5.18e-06	2	43	2	1.10.1630.10
Domain	Creb_binding	CREBBP EP300	5.18e-06	2	43	2	PF09030
Domain	-	CREBBP EP300	5.18e-06	2	43	2	1.10.246.20
Domain	zf-TAZ	CREBBP EP300	5.18e-06	2	43	2	PF02135
Domain	ZF_TAZ	CREBBP EP300	5.18e-06	2	43	2	PS50134
Domain	Histone_AcTrfase_Rtt109/CBP	CREBBP EP300	5.18e-06	2	43	2	IPR013178
Domain	KAT11	CREBBP EP300	5.18e-06	2	43	2	SM01250
Domain	Znf_TAZ	CREBBP EP300	5.18e-06	2	43	2	IPR000197
Domain	KIX_dom	CREBBP EP300	5.18e-06	2	43	2	IPR003101
Domain	KIX	CREBBP EP300	5.18e-06	2	43	2	PF02172
Domain	CBP_P300_HAT	CREBBP EP300	5.18e-06	2	43	2	PS51727
Domain	Nuc_rcpt_coact	CREBBP EP300	7.72e-05	6	43	2	IPR009110
Domain	BROMODOMAIN_1	CREBBP EP300 BRWD3	8.36e-05	37	43	3	PS00633
Domain	Bromodomain	CREBBP EP300 BRWD3	9.07e-05	38	43	3	PF00439
Domain	BROMODOMAIN_2	CREBBP EP300 BRWD3	1.14e-04	41	43	3	PS50014
Domain	BROMO	CREBBP EP300 BRWD3	1.23e-04	42	43	3	SM00297
Domain	Bromodomain	CREBBP EP300 BRWD3	1.23e-04	42	43	3	IPR001487
Domain	-	CREBBP EP300 BRWD3	1.23e-04	42	43	3	1.20.920.10
Domain	ZZ	CREBBP EP300	7.74e-04	18	43	2	PF00569
Domain	ZF_ZZ_2	CREBBP EP300	7.74e-04	18	43	2	PS50135
Domain	ZF_ZZ_1	CREBBP EP300	7.74e-04	18	43	2	PS01357
Domain	Znf_ZZ	CREBBP EP300	8.64e-04	19	43	2	IPR000433
Domain	ZnF_ZZ	CREBBP EP300	8.64e-04	19	43	2	SM00291
Domain	Bromodomain_CS	CREBBP EP300	1.62e-03	26	43	2	IPR018359
Domain	HMG_box	SOX9 UBTF	6.62e-03	53	43	2	PF00505
Domain	HMG_BOX_2	SOX9 UBTF	6.87e-03	54	43	2	PS50118
Domain	HMG	SOX9 UBTF	6.87e-03	54	43	2	SM00398
Domain	-	SOX9 UBTF	7.12e-03	55	43	2	1.10.30.10
Pathway	BIOCARTA_VDR_PATHWAY	ARID1A CREBBP EP300	9.42e-06	22	27	3	MM1370
Pathway	BIOCARTA_NTHI_PATHWAY	MAP2K3 CREBBP EP300	9.42e-06	22	27	3	MM1443
Pathway	BIOCARTA_NTHI_PATHWAY	MAP2K3 CREBBP EP300	1.08e-05	23	27	3	M2821
Pathway	BIOCARTA_VDR_PATHWAY	ARID1A CREBBP EP300	1.23e-05	24	27	3	M13404
Pathway	PID_MYC_ACTIV_PATHWAY	CREBBP HSPA4 UBTF EP300	1.45e-05	79	27	4	M66
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	3.52e-05	5	27	2	MM1575
Pathway	REACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES	CREBBP EP300	3.52e-05	5	27	2	M48020
Pathway	REACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES	CREBBP EP300	3.52e-05	5	27	2	M48023
Pathway	REACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION	CREBBP EP300	3.52e-05	5	27	2	M27228
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	5.27e-05	6	27	2	M22062
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP EP300	7.38e-05	7	27	2	MM1573
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP EP300	9.82e-05	8	27	2	M22058
Pathway	REACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES	CREBBP EP300	9.82e-05	8	27	2	M48022
Pathway	REACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION	CREBBP EP300	9.82e-05	8	27	2	M48024
Pathway	REACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES	CREBBP EP300	9.82e-05	8	27	2	M46443
Pathway	KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY	CREBBP EP300	1.26e-04	9	27	2	M47451
Pathway	REACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION	CREBBP EP300	1.57e-04	10	27	2	M27945
Pathway	WP_HEPATITIS_B_INFECTION	CASP8 MAP2K3 CREBBP EP300	1.83e-04	151	27	4	M39801
Pathway	BIOCARTA_CARM1_PATHWAY	CREBBP EP300	1.92e-04	11	27	2	MM1521
Pathway	REACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES	CREBBP EP300	1.92e-04	11	27	2	M48021
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR	CREBBP EP300	1.92e-04	11	27	2	M26924
Pathway	BIOCARTA_CARM1_PATHWAY	CREBBP EP300	2.30e-04	12	27	2	M7968
Pathway	REACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS	CREBBP EP300	2.30e-04	12	27	2	M27765
Pathway	PID_RB_1PATHWAY	CREBBP UBTF EP300	2.53e-04	65	27	3	M279
Pathway	WP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA	ARID1A CREBBP EP300	2.53e-04	65	27	3	M39682
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	CREBBP EP300	3.17e-04	14	27	2	M27808
Pathway	BIOCARTA_RELA_PATHWAY	CREBBP EP300	3.65e-04	15	27	2	MM1339
Pathway	BIOCARTA_RELA_PATHWAY	CREBBP EP300	3.65e-04	15	27	2	M10183
Pathway	BIOCARTA_PITX2_PATHWAY	CREBBP EP300	3.65e-04	15	27	2	MM1439
Pathway	REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY	CREBBP EP300	3.65e-04	15	27	2	M953
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS	CREBBP EP300	4.17e-04	16	27	2	M27121
Pathway	BIOCARTA_IL7_PATHWAY	CREBBP EP300	4.17e-04	16	27	2	M1296
Pathway	BIOCARTA_IL7_PATHWAY	CREBBP EP300	4.17e-04	16	27	2	MM1420
Pathway	BIOCARTA_PITX2_PATHWAY	CREBBP EP300	4.17e-04	16	27	2	M8516
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES	CREBBP EP300	4.17e-04	16	27	2	M27940
Pathway	BIOCARTA_TGFB_PATHWAY	CREBBP EP300	4.72e-04	17	27	2	MM1509
Pathway	REACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA	CREBBP EP300	4.72e-04	17	27	2	M48025
Pathway	REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA	CASP8 CREBBP EP300	5.02e-04	82	27	3	M1002
Pathway	REACTOME_RORA_ACTIVATES_GENE_EXPRESSION	CREBBP EP300	5.30e-04	18	27	2	M26942
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION	CREBBP EP300 MED8	5.38e-04	84	27	3	M1008
Pathway	BIOCARTA_TGFB_PATHWAY	CREBBP EP300	5.92e-04	19	27	2	M18933
Pathway	REACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES	CREBBP EP300	5.92e-04	19	27	2	M46442
Pathway	REACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	CREBBP EP300	6.57e-04	20	27	2	M27881
Pathway	WP_TNFALPHA_SIGNALING	CASP8 MAP2K3 CREBBP	7.02e-04	92	27	3	M39662
Pathway	WP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX	CREBBP EP300	7.25e-04	21	27	2	M39593
Pathway	REACTOME_CD209_DC_SIGN_SIGNALING	CREBBP EP300	7.25e-04	21	27	2	M27485
Pathway	REACTOME_RSV_HOST_INTERACTIONS	CREBBP EP300 MED8	8.44e-04	98	27	3	M48247
Pathway	REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS	CREBBP HSPA4 EP300	9.21e-04	101	27	3	M27253
Pathway	REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT	SOX9 DACT1 CREBBP EP300	9.47e-04	233	27	4	M27099
Pathway	REACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	CREBBP EP300	1.03e-03	25	27	2	M27880
Pathway	BIOCARTA_CARM_ER_PATHWAY	CREBBP EP300	1.12e-03	26	27	2	M2499
Pathway	PID_HDAC_CLASSIII_PATHWAY	CREBBP EP300	1.12e-03	26	27	2	M32
Pathway	REACTOME_ADIPOGENESIS	CREBBP EP300 MED8	1.18e-03	110	27	3	M48259
Pathway	REACTOME_ATTENUATION_PHASE	CREBBP EP300	1.29e-03	28	27	2	M27254
Pathway	REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA	CREBBP EP300 MED8	1.44e-03	118	27	3	M27316
Pathway	PID_RETINOIC_ACID_PATHWAY	CREBBP EP300	1.49e-03	30	27	2	M207
Pathway	REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION	CREBBP EP300	1.49e-03	30	27	2	M936
Pathway	REACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_PATHWAY	CREBBP EP300 MED8	1.52e-03	120	27	3	M48233
Pathway	WP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR	CREBBP EP300	1.69e-03	32	27	2	M39521
Pathway	WP_TYPE_2_PAPILLARY_RENAL_CELL_CARCINOMA	CREBBP EP300	1.91e-03	34	27	2	M39771
Pathway	REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN	ARID1A EP300	1.91e-03	34	27	2	MM15531
Pathway	PID_HIF2PATHWAY	CREBBP EP300	1.91e-03	34	27	2	M44
Pathway	REACTOME_EVASION_BY_RSV_OF_HOST_INTERFERON_RESPONSES	CREBBP EP300	2.02e-03	35	27	2	M48246
Pathway	REACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT	SOX9 ARID1A CREBBP	2.21e-03	137	27	3	M48232
Pathway	REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN	ARID1A EP300	2.26e-03	37	27	2	M27797
Pathway	REACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE	EXOC6 CCP110 CREBBP PLK4	2.31e-03	297	27	4	M27050
Pathway	REACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS	CASP8 CREBBP EP300	2.35e-03	140	27	3	M27484
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS	CREBBP EP300	2.38e-03	38	27	2	M27757
Pathway	REACTOME_HSF1_DEPENDENT_TRANSACTIVATION	CREBBP EP300	2.38e-03	38	27	2	M27255
Pathway	PID_FOXM1_PATHWAY	CREBBP EP300	2.63e-03	40	27	2	M176
Pathway	PID_IFNG_PATHWAY	CREBBP EP300	2.63e-03	40	27	2	M161
Pathway	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	CREBBP EP300	2.90e-03	42	27	2	M17541
Pathway	WP_SPLICING_FACTOR_NOVA_REGULATED_SYNAPTIC_PROTEINS	DAB1 KCNMA1	2.90e-03	42	27	2	M39703
Pathway	WP_SPLICING_FACTOR_NOVA_REGULATED_SYNAPTIC_PROTEINS	DAB1 KCNMA1	2.90e-03	42	27	2	MM15822
Pathway	PID_HNF3A_PATHWAY	CREBBP EP300	3.18e-03	44	27	2	M285
Pathway	REACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS	CREBBP EP300	3.18e-03	44	27	2	M27295
Pathway	REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT	SOX9 DACT1 EP300	3.32e-03	158	27	3	MM14791
Pathway	REACTOME_SIGNALING_BY_WNT	SOX9 DACT1 CREBBP EP300	3.38e-03	330	27	4	M7847
Pathway	PID_TNF_PATHWAY	CASP8 MAP2K3	3.47e-03	46	27	2	M128
Pathway	KEGG_NOTCH_SIGNALING_PATHWAY	CREBBP EP300	3.62e-03	47	27	2	M7946
Pathway	PID_HES_HEY_PATHWAY	CREBBP EP300	3.77e-03	48	27	2	M288
Pathway	REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	CREBBP EP300	3.77e-03	48	27	2	M611
Pathway	REACTOME_HEME_SIGNALING	CREBBP EP300	3.93e-03	49	27	2	M41832
Pathway	REACTOME_SIGNALING_BY_NOTCH3	CREBBP EP300	3.93e-03	49	27	2	M618
Pathway	PID_FOXO_PATHWAY	CREBBP EP300	3.93e-03	49	27	2	M136
Pathway	REACTOME_TRANSCRIPTIONAL_AND_POST_TRANSLATIONAL_REGULATION_OF_MITF_M_EXPRESSION_AND_ACTIVITY	SOX9 CREBBP	4.25e-03	51	27	2	M48267
Pathway	BIOCARTA_PPARA_PATHWAY	CREBBP EP300	4.42e-03	52	27	2	M2404
Pathway	PID_NFAT_3PATHWAY	CREBBP EP300	4.58e-03	53	27	2	M113
Pathway	PID_AR_TF_PATHWAY	CREBBP EP300	4.58e-03	53	27	2	M151
Pathway	WP_TGFBETA_SIGNALING_PATHWAY	CREBBP EP300	4.58e-03	53	27	2	MM15880
Pathway	WP_TGFBETA_RECEPTOR_SIGNALING	CREBBP EP300	4.93e-03	55	27	2	M39351
Pathway	KEGG_HUNTINGTONS_DISEASE	CASP8 CREBBP EP300	4.93e-03	182	27	3	M13486
Pathway	REACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER	CREBBP EP300	5.47e-03	58	27	2	M29616
Pathway	PID_P53_REGULATION_PATHWAY	CREBBP EP300	5.65e-03	59	27	2	M261
Pathway	WP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS	CREBBP EP300	5.65e-03	59	27	2	M39886
Pubmed	Smad3 induces chondrogenesis through the activation of SOX9 via CREB-binding protein/p300 recruitment.	SOX9 CREBBP EP300	2.31e-08	5	47	3	15623506
Pubmed	Transcriptional co-activators CREB-binding protein and p300 regulate chondrocyte-specific gene expression via association with Sox9.	SOX9 CREBBP EP300	2.31e-08	5	47	3	12732631
Pubmed	DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity.	WDFY3 CREBBP EP300 BRWD3 MED8	2.35e-07	99	47	5	34161765
Pubmed	CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.	CREBBP HSPA4 EP300	3.79e-07	11	47	3	36385105
Pubmed	Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos.	SOX9 CREBBP EP300	1.55e-06	17	47	3	18330926
Pubmed	Loss of p300 accelerates MDS-associated leukemogenesis.	CREBBP EP300	1.79e-06	2	47	2	27881875
Pubmed	Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.	CREBBP EP300	1.79e-06	2	47	2	34845315
Pubmed	p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.	CREBBP EP300	1.79e-06	2	47	2	19729597
Pubmed	Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.	CREBBP EP300	1.79e-06	2	47	2	15860545
Pubmed	Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.	CREBBP EP300	1.79e-06	2	47	2	29460469
Pubmed	Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.	CREBBP EP300	1.79e-06	2	47	2	24551300
Pubmed	Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.	CREBBP EP300	1.79e-06	2	47	2	33911074
Pubmed	The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.	CREBBP EP300	1.79e-06	2	47	2	9018065
Pubmed	Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.	CREBBP EP300	1.79e-06	2	47	2	24648406
Pubmed	CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.	CREBBP EP300	1.79e-06	2	47	2	30135524
Pubmed	CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.	CREBBP EP300	1.79e-06	2	47	2	39287984
Pubmed	Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.	CREBBP EP300	1.79e-06	2	47	2	16596650
Pubmed	The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.	CREBBP EP300	1.79e-06	2	47	2	29217654
Pubmed	Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.	CREBBP EP300	1.79e-06	2	47	2	20717166
Pubmed	Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.	CREBBP EP300	1.79e-06	2	47	2	10049825
Pubmed	CBP/p300 acetyltransferase activity in hematologic malignancies.	CREBBP EP300	1.79e-06	2	47	2	27380996
Pubmed	PLK4 phosphorylation of CP110 is required for efficient centriole assembly.	CCP110 PLK4	1.79e-06	2	47	2	28562169
Pubmed	CREBBP and p300 lysine acetyl transferases in the DNA damage response.	CREBBP EP300	1.79e-06	2	47	2	29170789
Pubmed	The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.	CREBBP EP300	1.79e-06	2	47	2	25893291
Pubmed	Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.	CREBBP EP300	1.79e-06	2	47	2	11559821
Pubmed	Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.	CREBBP EP300	1.79e-06	2	47	2	21555743
Pubmed	CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.	CREBBP EP300	1.79e-06	2	47	2	12646247
Pubmed	CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.	CREBBP EP300	1.79e-06	2	47	2	32576962
Pubmed	Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.	CREBBP EP300	1.79e-06	2	47	2	19822209
Pubmed	A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.	CREBBP EP300	1.79e-06	2	47	2	24522976
Pubmed	Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.	CREBBP EP300	1.79e-06	2	47	2	11867645
Pubmed	CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.	CREBBP EP300	1.79e-06	2	47	2	21847097
Pubmed	Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.	CREBBP EP300	1.79e-06	2	47	2	11963968
Pubmed	p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.	CREBBP EP300	1.79e-06	2	47	2	34813504
Pubmed	Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.	CREBBP EP300	1.79e-06	2	47	2	9528808
Pubmed	Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.	CREBBP EP300	1.79e-06	2	47	2	12696060
Pubmed	Rubinstein-Taybi Syndrome	CREBBP EP300	1.79e-06	2	47	2	20301699
Pubmed	CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.	CREBBP EP300	1.79e-06	2	47	2	36109165
Pubmed	Potential biomarker of metformin action.	CREBBP EP300	1.79e-06	2	47	2	24639469
Pubmed	The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.	CREBBP EP300	1.79e-06	2	47	2	37816914
Pubmed	Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.	CREBBP EP300	1.79e-06	2	47	2	12242694
Pubmed	Binding of p300/CBP co-activators by polyoma large T antigen.	CREBBP EP300	1.79e-06	2	47	2	11438528
Pubmed	Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.	CREBBP EP300	1.79e-06	2	47	2	10918613
Pubmed	CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.	CREBBP EP300	1.79e-06	2	47	2	31182547
Pubmed	Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.	CREBBP EP300	1.79e-06	2	47	2	35502657
Pubmed	Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.	CREBBP EP300	1.79e-06	2	47	2	30635043
Pubmed	p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.	CREBBP EP300	1.79e-06	2	47	2	31898871
Pubmed	Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.	CREBBP EP300	1.79e-06	2	47	2	27648933
Pubmed	Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.	CREBBP EP300	1.79e-06	2	47	2	30888860
Pubmed	Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.	CREBBP EP300	1.79e-06	2	47	2	27881443
Pubmed	Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.	CREBBP EP300	1.79e-06	2	47	2	19272189
Pubmed	Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.	CREBBP EP300	1.79e-06	2	47	2	10610021
Pubmed	Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.	CREBBP EP300	1.79e-06	2	47	2	37314181
Pubmed	Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.	CREBBP EP300	1.79e-06	2	47	2	12397173
Pubmed	CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.	CREBBP EP300	1.79e-06	2	47	2	15641773
Pubmed	Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.	CREBBP EP300	1.79e-06	2	47	2	32690000
Pubmed	Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.	CREBBP EP300	1.79e-06	2	47	2	9733868
Pubmed	CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.	CREBBP EP300	1.79e-06	2	47	2	30953353
Pubmed	Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.	CREBBP EP300	1.79e-06	2	47	2	21803292
Pubmed	HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.	CREBBP EP300	1.79e-06	2	47	2	9811832
Pubmed	Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.	CREBBP EP300	1.79e-06	2	47	2	24089570
Pubmed	Rubinstein-Taybi syndrome in Chinese population with four novel mutations.	CREBBP EP300	1.79e-06	2	47	2	33063428
Pubmed	EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.	CREBBP EP300	1.79e-06	2	47	2	34506759
Pubmed	Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.	CREBBP EP300	1.79e-06	2	47	2	22177454
Pubmed	Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.	CREBBP EP300	1.79e-06	2	47	2	15706485
Pubmed	AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.	CREBBP EP300	1.79e-06	2	47	2	39266679
Pubmed	A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.	CREBBP EP300	1.79e-06	2	47	2	22303793
Pubmed	Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.	CREBBP EP300	1.79e-06	2	47	2	34732714
Pubmed	Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.	CREBBP EP300	1.79e-06	2	47	2	34019788
Pubmed	Genes, plasticity and mental retardation.	DAB1 GRIA3 CREBBP	2.21e-06	19	47	3	18329113
Pubmed	Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.	GRIA3 CREBBP EP300 EIF4G2	2.37e-06	69	47	4	32238831
Pubmed	Composite co-activator ARC mediates chromatin-directed transcriptional activation.	CREBBP EP300 MED8	4.02e-06	23	47	3	10235267
Pubmed	Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.	CREBBP EP300	5.36e-06	3	47	2	14716005
Pubmed	The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.	CREBBP EP300	5.36e-06	3	47	2	18070920
Pubmed	The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression.	CREBBP EP300	5.36e-06	3	47	2	21967847
Pubmed	CBP and p300 are essential for renin cell identity and morphological integrity of the kidney.	CREBBP EP300	5.36e-06	3	47	2	19252086
Pubmed	Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.	CREBBP EP300	5.36e-06	3	47	2	27903646
Pubmed	Inhibition of p300/CBP by early B-cell factor.	CREBBP EP300	5.36e-06	3	47	2	12748286
Pubmed	p300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively.	CREBBP EP300	5.36e-06	3	47	2	10075656
Pubmed	Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.	CREBBP EP300	5.36e-06	3	47	2	24340053
Pubmed	Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response.	CREBBP EP300	5.36e-06	3	47	2	19273602
Pubmed	Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation.	CREBBP EP300	5.36e-06	3	47	2	15649887
Pubmed	Expression patterns of histone acetyltransferases p300 and CBP during murine tooth development.	CREBBP EP300	5.36e-06	3	47	2	22179676
Pubmed	CBP/p300 are bimodal regulators of Wnt signaling.	CREBBP EP300	5.36e-06	3	47	2	17410209
Pubmed	DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes.	CREBBP EP300	5.36e-06	3	47	2	26951377
Pubmed	CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.	CREBBP EP300	5.36e-06	3	47	2	21789216
Pubmed	Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex.	CREBBP EP300	5.36e-06	3	47	2	12050117
Pubmed	Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.	CREBBP EP300	5.36e-06	3	47	2	16237459
Pubmed	A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.	CREBBP EP300	5.36e-06	3	47	2	12384703
Pubmed	Regulation of transcription factor C/ATF by the cAMP signal activation in hippocampal neurons, and molecular interaction of C/ATF with signal integrator CBP/p300.	CREBBP EP300	5.36e-06	3	47	2	10350644
Pubmed	Loss of p300 and CBP disrupts histone acetylation at the mouse Sry promoter and causes XY gonadal sex reversal.	CREBBP EP300	5.36e-06	3	47	2	29145650
Pubmed	Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP.	CREBBP EP300	5.36e-06	3	47	2	7870179
Pubmed	The IFNgamma-induced STAT1-CBP/P300 association, required for a normal response to the cytokine, is disrupted in Brucella-infected macrophages.	CREBBP EP300	5.36e-06	3	47	2	19041714
Pubmed	Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP.	CREBBP EP300	5.36e-06	3	47	2	12776737
Pubmed	Convergence of Canonical and Non-Canonical Wnt Signal: Differential Kat3 Coactivator Usage.	CREBBP EP300	5.36e-06	3	47	2	30836930
Pubmed	Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation.	CREBBP EP300	5.36e-06	3	47	2	14759370
Pubmed	Activation of Smad1-mediated transcription by p300/CBP.	CREBBP EP300	5.36e-06	3	47	2	10673036
Pubmed	Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.	CREBBP EP300	5.36e-06	3	47	2	12456660
Pubmed	Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.	CREBBP EP300	5.36e-06	3	47	2	22474372
Pubmed	Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1.	CREBBP EP300	5.36e-06	3	47	2	9488451
Cytoband	Ensembl 112 genes in cytogenetic band chrXq28	HSFX3 HSFX4 DUSP9	1.37e-03	213	47	3	chrXq28
Cytoband	Ensembl 112 genes in cytogenetic band chr18q22	C18orf63 ZNF407	2.17e-03	67	47	2	chr18q22
Cytoband	9p13.3	FAM219A NOL6	2.71e-03	75	47	2	9p13.3
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CREBBP EP300	2.88e-04	17	27	2	486
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CREBBP EP300	3.24e-04	18	27	2	91
GeneFamily	X-linked mental retardation\|Angiotensin receptors	GRIA3 BRWD3	2.82e-03	53	27	2	103
GeneFamily	Sterile alpha motif domain containing	SAMD9 L3MBTL4	7.60e-03	88	27	2	760
CoexpressionAtlas	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4	ZSCAN29 SOX9 CCP110 WDFY3 ARID1A HSPA4 PLK4 BRWD3 MED8 DUSP9 PLCE1 EIF4G2	1.94e-05	1370	45	12	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlas	kidney_e10.5_UretericTrunk_HoxB7_top-relative-expression-ranked_1000	SOX9 CCP110 IKZF2 WDFY3 BRWD3 CARMIL1 MED8 DUSP9 SH3YL1	3.90e-05	802	45	9	gudmap_kidney_e10.5_UretericTrunk_HoxB7_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#3_top-relative-expression-ranked_500	KCNMA1 SYNPO2 FAM13C	6.57e-05	37	45	3	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k3_500
ToppCell	moderate-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ASNSD1 CCP110 NETO2 PLK4 PLCE1	1.68e-06	194	46	5	dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DAB1 KCNMA1 GRIA3 SYNPO2 FAM13C	1.95e-06	200	46	5	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DACT1 SYNPO2 FAM13C PLCE1	2.65e-05	167	46	4	7cb1b11e8e24a10115e46ffbb74889e672a7a026
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DACT1 SYNPO2 FAM13C PLCE1	2.65e-05	167	46	4	bb53a478b5d821d6d82c15bc4ed075b67682457c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DACT1 SYNPO2 FAM13C PLCE1	2.65e-05	167	46	4	e228b8373ffd4436e6b944e26d0fadf3ac289b21
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	KCNMA1 CARMIL1 L3MBTL4 PLCE1	2.90e-05	171	46	4	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KCNMA1 GRIA3 SYNPO2 PLCE1	3.18e-05	175	46	4	d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KCNMA1 GRIA3 SYNPO2 PLCE1	3.18e-05	175	46	4	454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 GRIA3 CARMIL1 DUSP9	3.25e-05	176	46	4	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 GRIA3 CARMIL1 DUSP9	3.25e-05	176	46	4	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	facs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 GRIA3 CARMIL1 DUSP9	3.55e-05	180	46	4	bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCell	facs-Marrow-B-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 GRIA3 CARMIL1 DUSP9	3.55e-05	180	46	4	839defb40f7cfb2711e9025194de636533f51bcd
ToppCell	facs-Marrow-B-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 GRIA3 CARMIL1 DUSP9	3.55e-05	180	46	4	82965ed1b72a1873c24dd4553d39681596057316
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB1 GRIA3 PLK4 PLCE1	3.55e-05	180	46	4	da723df348d7b8449bb1124f23fe6fa706412adb
ToppCell	droplet-Heart-nan-3m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB1 GRIA3 PLK4 PLCE1	3.55e-05	180	46	4	5b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB1 GRIA3 PLK4 PLCE1	3.55e-05	180	46	4	50758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCell	facs-Marrow-B-cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 GRIA3 CARMIL1 DUSP9	3.62e-05	181	46	4	e2481291c236105774c53883e6f20da11941df9b
ToppCell	facs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 GRIA3 CARMIL1 DUSP9	3.62e-05	181	46	4	782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCell	Immune_cells-Dendritic_cells\|Immune_cells / Lineage and Cell class	RPGRIP1 GRIA3 CARMIL1 DUSP9	3.70e-05	182	46	4	99c7d4f1e7cd745643ba64b59190113bcd4e348e
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DAB1 SVEP1 L3MBTL4 PLCE1	3.95e-05	185	46	4	cefd81adb480c027545a5c78dcd05669783717f4
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DAB1 KCNMA1 SYNPO2 FAM13C	4.03e-05	186	46	4	6add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-chondrocyte\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SOX9 DACT1 FAM13C SVEP1	4.20e-05	188	46	4	c9270517e6940e9793586f67f02431210552f278
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EXOC6 SYNPO2 CARMIL1 DPY19L2P1	4.29e-05	189	46	4	a75226616340045b581d08429d2e123e041dee55
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	DAB1 KCNMA1 SYNPO2 CARMIL1	4.29e-05	189	46	4	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KCNMA1 SYNPO2 CARMIL1 PLCE1	4.29e-05	189	46	4	975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCell	NS-moderate-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CCP110 NETO2 PLK4 PLCE1	4.38e-05	190	46	4	250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX9 DACT1 SVEP1 PLCE1	4.47e-05	191	46	4	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KCNMA1 SYNPO2 CARMIL1 PLCE1	4.56e-05	192	46	4	b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KCNMA1 SYNPO2 CARMIL1 PLCE1	4.56e-05	192	46	4	bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCell	moderate-Epithelial-FOXN4+\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CCP110 NETO2 PLK4 PLCE1	4.75e-05	194	46	4	5dffa578149104dda33774361e9e77b227b5f1ce
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNMA1 SYNPO2 CARMIL1 DPY19L2P1	4.84e-05	195	46	4	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	NETO2 PLK4 MOBP PLCE1	5.04e-05	197	46	4	1ffbbe44db0fd3ebd91ad16ab0b91153de5d7c6d
ToppCell	critical-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ASNSD1 NETO2 PLK4 PLCE1	5.34e-05	200	46	4	f39db4250ce220a3eb58edee3f7fc3671701d46f
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DAB1 KCNMA1 SYNPO2 FAM13C	5.34e-05	200	46	4	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	LPS_IL1RA-Mesenchymal_myocytic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KCNMA1 DACT1 SYNPO2 PLCE1	5.34e-05	200	46	4	77631c471cc5d453a749784f838cfa6408caf09b
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNMA1 IKZF2 FAM13C	3.42e-04	132	46	3	4152529611eeacf0c547e2a134d5b98c45426b13
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZSCAN29 IKZF2 PLK4	4.87e-04	149	46	3	65778f19599b4955c0a16f0121237656449431fb
ToppCell	Serous\|World / shred by cell class for turbinate	KCNMA1 SOX9 CARMIL1	4.96e-04	150	46	3	6a326662d58b0f17d6efa8cc28571f4cbbf57c2d
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_C\|E18.5-samps / Age Group, Lineage, Cell class and subclass	DACT1 SYNPO2 PLCE1	5.06e-04	151	46	3	3f2abaa42876ce7a71d934ff16abe0cab0991a05
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CREBBP PLK4 DUSP9	5.77e-04	158	46	3	91d265e95156f16459924d3e4dd11c180e164eee
ToppCell	TCGA-Bladder-Solid_Tissue_Normal\|TCGA-Bladder / Sample_Type by Project: Shred V9	KCNMA1 SYNPO2 SVEP1	5.99e-04	160	46	3	d6678996e12eaf2b735f1dfae32418cb2fabf268
ToppCell	TCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue\|TCGA-Bladder / Sample_Type by Project: Shred V9	KCNMA1 SYNPO2 SVEP1	5.99e-04	160	46	3	8a41e2c96e0e170ac35daf6c403bf961b8d7c30b
ToppCell	TCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue\|TCGA-Bladder / Sample_Type by Project: Shred V9	KCNMA1 SYNPO2 SVEP1	5.99e-04	160	46	3	c8dc575562b463fd30832d322c28006f18f7ab9c
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZSCAN29 PLK4 FAM219A	6.32e-04	163	46	3	63b0badaee3b2d827b1f4524510e3384d8f8fcde
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KCNMA1 GPR156 SYNPO2	6.32e-04	163	46	3	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	DACT1 FAM13C PLCE1	6.55e-04	165	46	3	3d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCell	15-Airway-Mesenchymal-Airway_Smooth_Muscle\|Airway / Age, Tissue, Lineage and Cell class	KCNMA1 SYNPO2 L3MBTL4	6.55e-04	165	46	3	531804467601e1ee1f771cffa21501f6d464ae10
ToppCell	ICU-SEP-Lymphocyte-T_NK-dnT\|ICU-SEP / Disease, Lineage and Cell Type	RPGRIP1 PLK4 FAM219A	6.66e-04	166	46	3	96d92316cee20b722fe782db9dafcceb8f2c220b
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB1 KCNMA1 FAM13C	6.78e-04	167	46	3	cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNMA1 SOX9 DUSP9	6.78e-04	167	46	3	102b3d160a44c8623fab1fd10e9054178c42a78b
ToppCell	droplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 CARMIL1 DUSP9	6.90e-04	168	46	3	e8878ec68b21c8d5694d7209b816d2f869673164
ToppCell	droplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 CARMIL1 DUSP9	6.90e-04	168	46	3	a007758c219d3d5db2b5529f29af63be0d408304
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 FAM13C SVEP1	6.90e-04	168	46	3	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 IKZF2 NETO2	6.90e-04	168	46	3	182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB1 KCNMA1 FAM13C	7.02e-04	169	46	3	30141f76e9bfc2b4586429857c72dbc85ba65cc9
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DAB1 SOX9 DACT1	7.02e-04	169	46	3	8f397cf4f9fd7c6fa88d01a95289ce2a6bc6938d
ToppCell	facs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 GRIA3 CARMIL1	7.26e-04	171	46	3	6a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCell	facs-Marrow-T-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 GRIA3 CARMIL1	7.26e-04	171	46	3	e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	DACT1 FAM13C PLCE1	7.26e-04	171	46	3	e59afa0a773dca3b9c208d17510ea55703b42598
ToppCell	droplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 CARMIL1 DUSP9	7.39e-04	172	46	3	24ecfda5e43e28f190089770cd2eae5bf2ed292b
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	IKZF2 SAMD9 SH3YL1	7.39e-04	172	46	3	9497948bbe53fb88c6ff6b347f743d456da587e5
ToppCell	droplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPGRIP1 CARMIL1 DUSP9	7.39e-04	172	46	3	db5a31cafce4346fe459d7f35210823fd7004439
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KCNMA1 SYNPO2 FAM13C	7.51e-04	173	46	3	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KCNMA1 SYNPO2 PLCE1	7.51e-04	173	46	3	901b8e6909c1f3849906fad9cee17b8f0bab050d
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KCNMA1 SYNPO2 PLCE1	7.51e-04	173	46	3	fc2602b2ce051cd4c33957d7e3d041ff8a529883
ToppCell	droplet-Spleen-nan-3m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA3 CARMIL1 DUSP9	7.76e-04	175	46	3	21bc0e59a9509d38751ce6aad2325f341bc70eff
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SVEP1 L3MBTL4 PLCE1	7.76e-04	175	46	3	9d09636a103daa8f622c3dbfd1f1536aaec3b6bb
ToppCell	NS-critical-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NETO2 PLK4 PLCE1	7.89e-04	176	46	3	7cf1a06ceee1ec06532f44c729c31b4d58e5ea49
ToppCell	droplet-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNMA1 DACT1 SYNPO2	8.02e-04	177	46	3	65709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SVEP1 L3MBTL4 PLCE1	8.02e-04	177	46	3	84116796ca4c7007508c0f1a68a1135c7b922278
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNMA1 DACT1 SYNPO2	8.02e-04	177	46	3	8684d47a547e2a06496f15e8da0200ecddc431e0
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SVEP1 L3MBTL4 PLCE1	8.16e-04	178	46	3	3c973aac16988e88f5677d3d695dd772ccfd6570
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SVEP1 L3MBTL4 PLCE1	8.16e-04	178	46	3	2a36475c260088f69f3b8c282d910e5eaa5c5c2d
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	KCNMA1 CARMIL1 PLCE1	8.29e-04	179	46	3	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DAB1 NETO2 L3MBTL4	8.29e-04	179	46	3	c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CASP8 IKZF2 SH3YL1	8.29e-04	179	46	3	593fc323b28304a57ae162f64b0890b893fff446
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CASP8 IKZF2 SH3YL1	8.29e-04	179	46	3	708fc0b8ffcb5fac43c52541acb6671fe1cfbb0d
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCP110 PLK4 PLCE1	8.42e-04	180	46	3	0c146e80d55d18b6988dd21b1da635801bd3140c
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_10\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GRIA3 SVEP1 L3MBTL4	8.42e-04	180	46	3	32d871738a24071b70084a7e80148a516110c78b
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCP110 PLK4 PLCE1	8.42e-04	180	46	3	e9af22beae2f3c7fe213b4e19df84abfd2453433
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	KCNMA1 SYNPO2 FAM13C	8.42e-04	180	46	3	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCP110 PLK4 PLCE1	8.42e-04	180	46	3	11455ba704ac73f69b474845136cfecec6a88349
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_10\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GRIA3 SVEP1 L3MBTL4	8.42e-04	180	46	3	067ca8a15228c7f3b3bc7aecbc9b1611ca05e176
ToppCell	E18.5-samps-Mesenchymal-Pericyte\|E18.5-samps / Age Group, Lineage, Cell class and subclass	DACT1 SYNPO2 PLCE1	8.42e-04	180	46	3	0b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KCNMA1 SYNPO2 FAM13C	8.56e-04	181	46	3	25915e2500430a902db37d79a749ce2990b69810
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GRIA3 SYNPO2 FAM13C	8.56e-04	181	46	3	eea943fdcbef0bbaa8578f3296923e874893b405
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SVEP1 L3MBTL4 PLCE1	8.56e-04	181	46	3	062f00736eed96e4f4327615d093558dd7d82b20
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GRIA3 SYNPO2 FAM13C	8.56e-04	181	46	3	9c157de9d3403e092c907599f2a2c16db5b21131
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DACT1 SYNPO2 SVEP1	8.56e-04	181	46	3	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DACT1 SYNPO2 SVEP1	8.56e-04	181	46	3	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	21-Trachea-Epithelial-Multiciliated_precursor\|Trachea / Age, Tissue, Lineage and Cell class	CCP110 NETO2 PLK4	8.70e-04	182	46	3	6e35892fa959ee31591850ded8f1088195ddeb01
ToppCell	wk_20-22-Hematologic-Meg-ery-Definitive_erythroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	RNF10 MAP2K3 EP300	8.70e-04	182	46	3	0c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SVEP1 L3MBTL4 PLCE1	8.70e-04	182	46	3	d3a037268f026eb2f84428b1821022503cef7756
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DACT1 SYNPO2 SVEP1	8.70e-04	182	46	3	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DAB1 L3MBTL4 PLCE1	8.70e-04	182	46	3	420a8fd30543e37a66ba0786215d056d308660d0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DACT1 SYNPO2 SVEP1	8.70e-04	182	46	3	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	KCNMA1 SYNPO2 CARMIL1	8.84e-04	183	46	3	818fd886e0188091310825f9145fa53328f2c979
ToppCell	facs-Skin-Telogen-3m-Epithelial-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF2 MAP2K3 HSPA4	8.84e-04	183	46	3	26b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCell	Pericytes-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	DACT1 SYNPO2 FAM13C	8.84e-04	183	46	3	4617b18da8d699a44e4c47980197b1e7eb951470
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GRIA3 SYNPO2 FAM13C	8.84e-04	183	46	3	bc7dd6a40ec9c773d005c1a46f305d40cdd0a326
Drug	Betazole hydrochloride; Up 200; 27uM; MCF7; HT_HG-U133A	CASP8 FNDC3A WDFY3 PLK4 SVEP1 PLCE1	2.15e-06	198	44	6	1690_UP
Drug	NSC-364372	SOX9 CASP8 DACT1 SYNPO2 MAP2K3 HSPA4 EP300 DUSP9	3.56e-06	484	44	8	CID000435143
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	WDFY3 ARID1A CREBBP UBTF EP300	1.93e-05	171	44	5	6879_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	WDFY3 ARID1A CREBBP UBTF EP300	1.99e-05	172	44	5	2794_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	WDFY3 ARID1A CREBBP UBTF EP300	2.04e-05	173	44	5	2881_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	WDFY3 ARID1A CREBBP UBTF EP300	2.10e-05	174	44	5	1659_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	WDFY3 ARID1A CREBBP UBTF EP300	2.16e-05	175	44	5	1058_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	WDFY3 ARID1A CREBBP PLK4 UBTF	2.22e-05	176	44	5	6784_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	WDFY3 ARID1A CREBBP UBTF EP300	2.28e-05	177	44	5	3227_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	FNDC3A ARID1A CREBBP PLK4 UBTF	2.28e-05	177	44	5	3177_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	ARID1A CREBBP PLK4 UBTF EP300	2.47e-05	180	44	5	3688_DN
Drug	Methoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; MCF7; HT_HG-U133A	ZNF407 SAMD9 MOBP SVEP1 DUSP9	3.12e-05	189	44	5	5455_UP
Drug	Benzbromarone [3562-84-3]; Up 200; 9.4uM; HL60; HT_HG-U133A	CASP8 FNDC3A HSPA4 PLK4 UBTF	3.12e-05	189	44	5	1291_UP
Drug	Rescinnamin [24815-24-5]; Down 200; 6.4uM; MCF7; HT_HG-U133A	SOX9 FNDC3A WDFY3 MAP2K3 MOBP	3.62e-05	195	44	5	4386_DN
Drug	3,4-dimethoxy-N-((2,2-dimethyl-2H-chromen-6-yl)methyl)-N-phenylbenzenesulfonamide	CREBBP EP300	3.64e-05	5	44	2	ctd:C575894
Drug	Midecamycin [35457-80-8]; Down 200; 5uM; MCF7; HT_HG-U133A	CASP8 WDFY3 ARID1A MAP2K3 UBTF	3.81e-05	197	44	5	1526_DN
Drug	Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; MCF7; HT_HG-U133A	CASP8 ZNF407 FNDC3A SAMD9 WDFY3	3.81e-05	197	44	5	4732_DN
Drug	Khellin [82-02-0]; Down 200; 15.4uM; MCF7; HT_HG-U133A	SOX9 CASP8 MAP2K3 HSPA4 PLK4	3.81e-05	197	44	5	1504_DN
Drug	Iproniazide phosphate [305-33-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A	SAMD9 CREBBP MOBP PLCE1 EIF4G2	3.90e-05	198	44	5	2288_UP
Drug	Tobramycin [32986-56-4]; Down 200; 8.6uM; PC3; HT_HG-U133A	ZNF407 FNDC3A SAMD9 MOBP EIF4G2	3.90e-05	198	44	5	4081_DN
Drug	Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A	SOX9 CASP8 SAMD9 WDFY3 NOL6	3.90e-05	198	44	5	3406_UP
Drug	5140203; Up 200; 15uM; MCF7; HT_HG-U133A_EA	CASP8 FNDC3A PLK4 DUSP9 EIF4G2	3.90e-05	198	44	5	908_UP
Drug	MBED	KCNMA1 HSPA4	5.45e-05	6	44	2	CID000129958
Drug	SP600125	CASP8 DACT1 MAP2K3 HSPA4 PLK4 EP300	6.57e-05	362	44	6	CID000008515
Drug	AC1L1IS7	CASP8 GRIA3 MAP2K3	9.03e-05	45	44	3	CID000004711
Drug	17alpha-estradiol	KCNMA1 SOX9 CASP8 FNDC3A MAP2K3 HSPA4 PLK4 UBTF EP300 PLCE1	1.51e-04	1303	44	10	CID000000450
Drug	Vanadium Compounds	CASP8 FNDC3A	1.63e-04	10	44	2	ctd:D017968
Drug	iclaprim	CREBBP HSPA4 EP300	2.35e-04	62	44	3	CID000213043
Drug	silicon carbide	IKZF2 UBTF	2.38e-04	12	44	2	CID000009863
Drug	Atpa	GRIA3 EIF4G2	2.38e-04	12	44	2	CID000002252
Drug	FeTMPyP	KCNMA1 CASP8	2.38e-04	12	44	2	CID009853416
Drug	glutamin	CASP8 WDFY3 ARID1A CREBBP HSPA4 EP300	2.45e-04	461	44	6	CID000000738
Drug	Camptothecin	CASP8 MAP2K3 CREBBP EP300	2.75e-04	163	44	4	ctd:D002166
Drug	belinostat	CASP8 DACT1 GRIA3 NETO2 DUSP9 PLCE1 EIF4G2	2.96e-04	678	44	7	ctd:C487081
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	WDFY3 ARID1A CREBBP UBTF	3.08e-04	168	44	4	3395_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	WDFY3 ARID1A CREBBP UBTF	3.15e-04	169	44	4	6064_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	ARID1A CREBBP PLK4 UBTF	3.23e-04	170	44	4	3791_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	ARID1A CREBBP UBTF EP300	3.23e-04	170	44	4	1050_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	ARID1A CREBBP UBTF EP300	3.23e-04	170	44	4	3746_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A CREBBP PLK4 UBTF	3.30e-04	171	44	4	7407_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	WDFY3 ARID1A CREBBP UBTF	3.30e-04	171	44	4	4954_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	WDFY3 ARID1A CREBBP UBTF	3.37e-04	172	44	4	3428_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	ARID1A CREBBP PLK4 UBTF	3.37e-04	172	44	4	7073_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	KCNMA1 ARID1A CREBBP UBTF	3.37e-04	172	44	4	6439_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A MAP2K3 CREBBP UBTF	3.37e-04	172	44	4	1637_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A CREBBP UBTF EP300	3.45e-04	173	44	4	5987_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	WDFY3 ARID1A UBTF EP300	3.45e-04	173	44	4	5950_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	ARID1A CREBBP UBTF EP300	3.45e-04	173	44	4	4458_DN
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A	SOX9 CASP8 FNDC3A HSPA4	3.52e-04	174	44	4	1651_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	CASP8 ARID1A UBTF EP300	3.52e-04	174	44	4	5065_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	WDFY3 ARID1A UBTF EP300	3.60e-04	175	44	4	5935_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	ARID1A CREBBP UBTF EP300	3.60e-04	175	44	4	1014_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	ARID1A CREBBP PLK4 UBTF	3.60e-04	175	44	4	3787_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A CREBBP PLK4 UBTF	3.68e-04	176	44	4	3312_DN
Drug	trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA	WDFY3 ARID1A CREBBP UBTF	3.68e-04	176	44	4	981_DN
Drug	17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A	KCNMA1 SOX9 CASP8 HSPA4	3.68e-04	176	44	4	1638_UP
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	ARID1A CREBBP PLK4 UBTF	3.68e-04	176	44	4	6546_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	ARID1A CREBBP UBTF EP300	3.76e-04	177	44	4	1645_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	ARID1A CREBBP UBTF EP300	3.76e-04	177	44	4	6434_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	ARID1A CREBBP UBTF EP300	3.76e-04	177	44	4	7047_DN
Drug	SAHA; Down 200; 10uM; PC3; HT_HG-U133A	ARID1A CREBBP UBTF EP300	3.84e-04	178	44	4	4444_DN
Drug	BAPTA	KCNMA1 GRIA3 FNDC3A MAP2K3 EIF4G2	3.90e-04	324	44	5	CID000104751
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	ARID1A CREBBP UBTF EP300	3.92e-04	179	44	4	6609_DN
Drug	radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A	SOX9 FNDC3A HSPA4 PLK4	3.92e-04	179	44	4	1644_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	WDFY3 ARID1A CREBBP UBTF	4.01e-04	180	44	4	6454_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	ARID1A CREBBP UBTF EP300	4.01e-04	180	44	4	4821_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	ARID1A CREBBP UBTF EP300	4.09e-04	181	44	4	6951_DN
Drug	1,4-benzothiazine	KCNMA1 CASP8	4.31e-04	16	44	2	CID003088997
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	WDFY3 ARID1A CREBBP UBTF	4.35e-04	184	44	4	6939_DN
Drug	Hycanthone [3105-97-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A	SOX9 WDFY3 SVEP1 PLCE1	4.35e-04	184	44	4	3229_UP
Drug	hydralazine	CASP8 WDFY3 HSPA4 EP300	4.53e-04	186	44	4	CID000003637
Drug	2-propylpentanoic acid; Down 200; 10000uM; HL60; HG-U133A	ARID1A NETO2 UBTF EP300	4.82e-04	189	44	4	410_DN
Drug	Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; PC3; HT_HG-U133A	KCNMA1 SOX9 CASP8 HSPA4	4.82e-04	189	44	4	4271_DN
Drug	Heterocyclic Compounds, 3-Ring	CASP8 EP300	4.87e-04	17	44	2	ctd:D006575
Drug	Oils, Galangal	CASP8 MAP2K3 HSPA4 EP300	4.91e-04	190	44	4	CID000002889
Drug	2-propylpentanoic acid; Down 200; 200uM; HL60; HT_HG-U133A	CASP8 HSPA4 PLK4 MED8	5.01e-04	191	44	4	6173_DN
Drug	Ethynodiol diacetate [297-76-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A	KCNMA1 ZNF407 MOBP EIF4G2	5.01e-04	191	44	4	6479_UP
Drug	Quinacrine dihydrochloride dihydrate [6151-30-0]; Up 200; 7.8uM; HL60; HG-U133A	CCP110 ARID1A MAP2K3 PLK4	5.01e-04	191	44	4	1563_UP
Drug	Pseudopelletierine hydrochloride [6164-62-1]; Down 200; 21uM; MCF7; HT_HG-U133A	CASP8 FNDC3A HSPA4 PLK4	5.11e-04	192	44	4	2766_DN
Drug	oxotremorine-M	CASP8 CHRM5 PLCE1	5.17e-04	81	44	3	CID000004629
Drug	thioridazine hydrochloride; Up 200; 10uM; HL60; HT_HG-U133A	ZNF407 ARID1A SVEP1 CARMIL1	5.21e-04	193	44	4	6189_UP
Drug	Tolmetin sodium salt dihydrate [64490-92-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A	SAMD9 WDFY3 ARID1A PLK4	5.21e-04	193	44	4	3347_UP
Drug	Podophyllotoxin [518-28-5]; Down 200; 9.6uM; HL60; HT_HG-U133A	FAM13C HSPA4 NOL6 PLCE1	5.21e-04	193	44	4	2540_DN
Drug	pioglitazone HCl; Up 200; 10uM; PC3; HT_HG-U133A	KCNMA1 ZNF407 WDFY3 ARID1A	5.21e-04	193	44	4	6893_UP
Drug	Ceforanide [60925-61-3]; Down 200; 7.6uM; PC3; HT_HG-U133A	CASP8 FNDC3A ARID1A UBTF	5.21e-04	193	44	4	6751_DN
Drug	5707885; Up 200; 50uM; MCF7; HT_HG-U133A	RPGRIP1 CASP8 PLK4 SVEP1	5.31e-04	194	44	4	6385_UP
Drug	Iopamidol [60166-93-0]; Up 200; 5.2uM; MCF7; HT_HG-U133A	SOX9 CASP8 HSPA4 PLK4	5.31e-04	194	44	4	7189_UP
Drug	5230742; Up 200; 17uM; MCF7; HT_HG-U133A_EA	FNDC3A EDC3 SAMD9 WDFY3	5.31e-04	194	44	4	862_UP
Drug	Benserazide hydrochloride [14919-77-8]; Down 200; 13.6uM; PC3; HT_HG-U133A	CASP8 FNDC3A UBTF MED8	5.31e-04	194	44	4	6722_DN
Drug	Tacrine hydrochloride hydrate [1684-40-8]; Up 200; 15.8uM; HL60; HT_HG-U133A	CASP8 FNDC3A HSPA4 PLK4	5.31e-04	194	44	4	1278_UP
Drug	Naproxen [22204-53-1]; Down 200; 17.4uM; MCF7; HT_HG-U133A	CASP8 FNDC3A WDFY3 EIF4G2	5.31e-04	194	44	4	5457_DN
Drug	Carteolol hydrochloride [51781-21-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A	CASP8 WDFY3 HSPA4 PLK4	5.31e-04	194	44	4	4176_DN
Drug	LY294002	KCNMA1 CASP8 FNDC3A MAP2K3 HSPA4 EP300 EIF4G2	5.33e-04	748	44	7	CID000003973
Drug	2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A	SOX9 ARID1A PLK4 UBTF	5.42e-04	195	44	4	1665_DN
Drug	wortmannin from Penicillium funiculosum; Up 200; 0.01uM; MCF7; HT_HG-U133A	SOX9 SAMD9 WDFY3 FAM13C	5.42e-04	195	44	4	5240_UP
Drug	Biperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; MCF7; HT_HG-U133A	SAMD9 MOBP SVEP1 DUSP9	5.42e-04	195	44	4	3321_UP
Drug	Diperodon hydrochloride [537-12-2]; Up 200; 9.2uM; HL60; HG-U133A	SAMD9 ARID1A EP300 MED8	5.42e-04	195	44	4	1575_UP
Drug	HY-1	CASP8 HSPA4	5.48e-04	18	44	2	CID000192888
Drug	N-acetyl-Leu-Leu-Nle-CHO	CASP8 MAP2K3	5.48e-04	18	44	2	CID016073817
Drug	Kawain [500-64-1]; Up 200; 17.4uM; PC3; HT_HG-U133A	CASP8 ARID1A PLK4 EIF4G2	5.52e-04	196	44	4	7369_UP
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	CASP8 IKZF2 CREBBP EP300	2.11e-06	61	44	4	C1961102
Disease	Menke-Hennekam syndrome	CREBBP EP300	2.17e-06	2	44	2	cv:C5681632
Disease	Rubinstein-Taybi syndrome (implicated_via_orthology)	CREBBP EP300	2.17e-06	2	44	2	DOID:1933 (implicated_via_orthology)
Disease	Rubinstein-Taybi syndrome	CREBBP EP300	2.17e-06	2	44	2	cv:C0035934
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	2.17e-06	2	44	2	C4551859
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	2.17e-06	2	44	2	180849
Disease	Rubinstein-Taybi syndrome due to CREBBP mutations	CREBBP EP300	2.17e-06	2	44	2	cv:C4551859
Disease	Rubinstein-Taybi syndrome (is_implicated_in)	CREBBP EP300	2.17e-06	2	44	2	DOID:1933 (is_implicated_in)
Disease	Rubinstein-Taybi Syndrome	CREBBP EP300	2.17e-06	2	44	2	C0035934
Disease	Adenoid Cystic Carcinoma	ARID1A NETO2 CREBBP EP300	1.52e-05	100	44	4	C0010606
Disease	Neoplasm of uncertain or unknown behavior of breast	CASP8 ARID1A EP300	3.17e-05	41	44	3	C0496956
Disease	Carcinoma, Transitional Cell	ARID1A CREBBP EP300	3.17e-05	41	44	3	C0007138
Disease	Breast adenocarcinoma	CASP8 ARID1A EP300	3.17e-05	41	44	3	C0858252
Disease	PARTINGTON X-LINKED MENTAL RETARDATION SYNDROME	GRIA3 BRWD3	6.05e-05	8	44	2	C0796250
Disease	neuroimaging measurement	DAB1 EXOC6 DACT1 SAMD9 MOBP CARMIL1 DUSP9 PLCE1	1.61e-04	1069	44	8	EFO_0004346
Disease	esophageal squamous cell carcinoma	CASP8 PLCE1	1.68e-04	13	44	2	EFO_0005922
Disease	alcohol use disorder (implicated_via_orthology)	KCNMA1 ARID1A CREBBP EP300	2.04e-04	195	44	4	DOID:1574 (implicated_via_orthology)
Disease	T-Cell Lymphoma	ARID1A EP300	2.57e-04	16	44	2	C0079772
Disease	heart disease (biomarker_via_orthology)	CASP8 EP300	2.91e-04	17	44	2	DOID:114 (biomarker_via_orthology)
Disease	Squamous cell carcinoma of esophagus	CREBBP EP300 PLCE1	3.89e-04	95	44	3	C0279626
Disease	mean fractional anisotropy measurement	DACT1 WDFY3 MOBP	3.89e-04	95	44	3	EFO_0008399
Disease	Headache, HbA1c measurement	CASP8 HSPA4	4.48e-04	21	44	2	EFO_0004541, HP_0002315
Disease	bilirubin measurement	EXOC6 ZNF407 ARID1A CARMIL1 L3MBTL4	4.95e-04	442	44	5	EFO_0004570
Disease	Renal glomerular disease	CREBBP PLCE1	5.39e-04	23	44	2	C0268731
Disease	Glomerulopathy Assessment	CREBBP PLCE1	5.39e-04	23	44	2	C4521256
Disease	blood urea nitrogen measurement	SYNPO2 IKZF2 DUSP9 PLCE1 SH3YL1	5.48e-04	452	44	5	EFO_0004741
Disease	Carcinoma, Granular Cell	CASP8 ARID1A PLCE1	6.97e-04	116	44	3	C0205644
Disease	Adenocarcinoma, Tubular	CASP8 ARID1A PLCE1	6.97e-04	116	44	3	C0205645
Disease	Adenocarcinoma, Oxyphilic	CASP8 ARID1A PLCE1	6.97e-04	116	44	3	C0205642
Disease	Carcinoma, Cribriform	CASP8 ARID1A PLCE1	6.97e-04	116	44	3	C0205643
Disease	Adenocarcinoma, Basal Cell	CASP8 ARID1A PLCE1	6.97e-04	116	44	3	C0205641
Disease	Adenocarcinoma	CASP8 ARID1A PLCE1	6.97e-04	116	44	3	C0001418
Disease	Sezary Syndrome	ARID1A CREBBP	7.45e-04	27	44	2	C0036920
Disease	cortical surface area measurement	DAB1 EXOC6 DACT1 SAMD9 UBTF MOBP SVEP1 PLCE1	7.47e-04	1345	44	8	EFO_0010736
Disease	glycoprotein measurement	EXOC6 CASP8 HSPA4	7.51e-04	119	44	3	EFO_0004555
Disease	Colorectal Neoplasms	CASP8 DACT1 ARID1A EP300	7.68e-04	277	44	4	C0009404
Disease	functional brain measurement, language measurement	DACT1 PLCE1	8.01e-04	28	44	2	EFO_0007797, EFO_0007849
Disease	esophageal carcinoma	CASP8 PLCE1	9.21e-04	30	44	2	EFO_0002916
Disease	retinal vasculature measurement	KCNMA1 EXOC6 L3MBTL4 PLCE1 SH3YL1	1.00e-03	517	44	5	EFO_0010554
Disease	liver iron measurement	ASNSD1 CARMIL1	1.11e-03	33	44	2	EFO_0010056
Disease	electrocardiography	DAB1 RNF10 RPGRIP1 CARMIL1 PLCE1	1.12e-03	530	44	5	EFO_0004327
Disease	sporadic amyotrophic lateral sclerosis	SYNPO2 ARID1A MOBP	1.20e-03	140	44	3	EFO_0001357
Disease	Bladder Neoplasm	ARID1A CREBBP EP300	1.20e-03	140	44	3	C0005695
Disease	Malignant neoplasm of urinary bladder	ARID1A CREBBP EP300	1.23e-03	141	44	3	C0005684

Protein segments in the cluster

Peptide	Gene	Start	Entry
TKSKNQSMKSPGTTP	C2orf16	451	Q68DN1
SSLSRGNKKKPGMPN	EP300	1561	Q09472
SRANKKKPSMPNVSN	CREBBP	1601	Q92793
KKPSMPNVSNDLSQK	CREBBP	1606	Q92793
SSGAPSPKGKQKQMK	BRWD3	1461	Q6RI45
NKDSKQKMPPGQVIS	KIAA1107	421	Q9UPP5
TPATKMNNKADGTPK	ARID1A	976	O14497
MKKQGVNPKPLQSSR	DPY19L2P1	1	Q6NXN4
TSQAGSKDKKMDQPP	HSPA4	551	P34932
PSTLSPKKKQRNGGM	KCNMA1	761	Q12791
FCKTRPSNSPGNKKM	HSFX4	146	A0A1B0GTS1
RMKLTKNTQNFKPAP	GRIA3	856	P42263
KNGSMGSPVNQQPKK	FAM219A	66	Q8IW50
FQPQPFKASSTKGRM	NOL6	1091	Q9H6R4
KRKKSNISPNFNFMG	DUSP9	321	Q99956
KKLFRNRSPNGPMSK	L3MBTL4	176	Q8NA19
QATPKKSGLKNGQMK	EDC3	171	Q96F86
FCKTRPSNSPGNKKM	HSFX3	146	A0A1B0GWH4
GNMGKRKSSTPQKFV	IKZF2	271	Q9UKS7
QGQSKDMPPRFSKKG	EIF4G2	451	P78344
EKQSFPKKFPMSQSV	EXOC6	471	Q8TAG9
LKKMSQKNSLQGVPP	DACT1	506	Q9NYF0
RSSPQTDKPRQKMGK	DAB1	431	O75553
KDRQGTQKDKMSSPP	FNDC3A	191	Q9Y2H6
GMPNKKFLVKQNPSE	CCP110	931	O43303
KKNMGKQMPQPTFTL	CASP8	456	Q14790
KTMPTTFNREGNKQK	ASNSD1	361	Q9NWL6
KNSAAFSPQKMPLSK	GPR156	576	Q8NFN8
LGKNFNNMKSKNLTP	CARMIL1	516	Q5VZK9
MNKNTSVLGSPKRKQ	C18orf63	446	Q68DL7
QPGKMPSGIKTNIKS	MED8	246	Q96G25
SSQPASMPQSKGKSK	MAP2K3	6	P46734
ASKGKNMKTQPPLSR	RPGRIP1	26	Q96KN7
PGTSAKNAEKPNMQR	PLCE1	1061	Q9P212
DPSQTMKKPKQNQLT	SSMEM1	96	Q8WWF3
SKMGKPSKNAPKDQT	SAMD9	86	Q5K651
MNNPIPSNLKSEAKK	SH3YL1	1	Q96HL8
MSQKPAKEGPRLSKN	MOBP	1	Q13875
AQPQPMKTFNSTFKK	NETO2	466	Q8NC67
NGSSKNKPHVKRPMN	SOX9	96	P48436
RPSMGNFKSRKPKSI	FAM13C	81	Q8NE31
QPLPNKMTVFPKNKS	PLK4	316	O00444
KKPNPVMNGSIKGSN	SVEP1	2776	Q4LDE5
KGLNPNPSHQMTKRK	CHRM5	416	P08912
PKTFRNLAKPMGAQT	WDFY3	2746	Q8IZQ1
APNPNSKGVLMFKKR	SYNPO2	386	Q9UMS6
SQKSKTFNKMPPQRG	RNF10	86	Q8N5U6
KQPFPKKSRTMATKN	ZNF407	286	Q9C0G0
QMNPKEKLKPFQRSG	ZSCAN29	161	Q8IWY8
PPAATNSSKKMKFQG	UBTF	551	P17480