Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionacetyl-CoA carboxylase activity

ACACB ACACA

1.81e-07292GO:0003989
GeneOntologyMolecularFunctionCoA carboxylase activity

ACACB ACACA

2.71e-06692GO:0016421
GeneOntologyMolecularFunctionbiotin binding

ACACB ACACA

2.71e-06692GO:0009374
GeneOntologyMolecularFunctionligase activity, forming carbon-carbon bonds

ACACB ACACA

3.79e-06792GO:0016885
GeneOntologyMolecularFunctionmonocarboxylic acid binding

ACACB ACACA

9.99e-0410792GO:0033293
GeneOntologyMolecularFunctionvitamin binding

ACACB ACACA

2.24e-0316192GO:0019842
GeneOntologyMolecularFunctionligase activity

ACACB ACACA

2.61e-0317492GO:0016874
GeneOntologyMolecularFunctioncarboxylic acid binding

ACACB ACACA

4.86e-0323992GO:0031406
GeneOntologyMolecularFunctionorganic acid binding

ACACB ACACA

5.47e-0325492GO:0043177
GeneOntologyMolecularFunctionamide binding

ACACB ACACA

7.51e-0329992GO:0033218
GeneOntologyMolecularFunctionsulfur compound binding

ACACB ACACA

8.71e-0332392GO:1901681
GeneOntologyBiologicalProcessmalonyl-CoA biosynthetic process

ACACB ACACA

1.69e-07292GO:2001295
GeneOntologyBiologicalProcessmalonyl-CoA metabolic process

ACACB ACACA

2.54e-06692GO:2001293
GeneOntologyBiologicalProcessacetyl-CoA metabolic process

ACACB ACACA

1.24e-043992GO:0006084
GeneOntologyBiologicalProcessthioester biosynthetic process

ACACB ACACA

1.97e-044992GO:0035384
GeneOntologyBiologicalProcessacyl-CoA biosynthetic process

ACACB ACACA

1.97e-044992GO:0071616
GeneOntologyBiologicalProcessnucleoside bisphosphate biosynthetic process

ACACB ACACA

3.06e-046192GO:0033866
GeneOntologyBiologicalProcessribonucleoside bisphosphate biosynthetic process

ACACB ACACA

3.06e-046192GO:0034030
GeneOntologyBiologicalProcesspurine nucleoside bisphosphate biosynthetic process

ACACB ACACA

3.06e-046192GO:0034033
GeneOntologyBiologicalProcessstriated muscle adaptation

ACACB TNNI1

4.38e-047392GO:0014888
GeneOntologyBiologicalProcessprotein homotetramerization

ACACB ACACA

4.87e-047792GO:0051289
GeneOntologyBiologicalProcessthioester metabolic process

ACACB ACACA

9.72e-0410992GO:0035383
GeneOntologyBiologicalProcessacyl-CoA metabolic process

ACACB ACACA

9.72e-0410992GO:0006637
GeneOntologyBiologicalProcessprotein tetramerization

ACACB ACACA

1.04e-0311392GO:0051262
GeneOntologyBiologicalProcesspurine ribonucleotide metabolic process

ACACB TPI1 ACACA

1.14e-0351293GO:0009150
GeneOntologyBiologicalProcessribonucleotide metabolic process

ACACB TPI1 ACACA

1.28e-0353393GO:0009259
GeneOntologyBiologicalProcessribose phosphate metabolic process

ACACB TPI1 ACACA

1.33e-0354093GO:0019693
GeneOntologyBiologicalProcessregulation of muscle adaptation

ACACB TNNI1

1.44e-0313392GO:0043502
GeneOntologyBiologicalProcessnucleoside bisphosphate metabolic process

ACACB ACACA

1.64e-0314292GO:0033865
GeneOntologyBiologicalProcessribonucleoside bisphosphate metabolic process

ACACB ACACA

1.64e-0314292GO:0033875
GeneOntologyBiologicalProcesspurine nucleoside bisphosphate metabolic process

ACACB ACACA

1.64e-0314292GO:0034032
GeneOntologyBiologicalProcesspurine nucleotide metabolic process

ACACB TPI1 ACACA

1.97e-0361993GO:0006163
GeneOntologyBiologicalProcessmuscle adaptation

ACACB TNNI1

2.18e-0316492GO:0043500
GeneOntologyBiologicalProcessorganophosphate biosynthetic process

ACACB TPI1 ACACA

2.21e-0364493GO:0090407
GeneOntologyBiologicalProcesspurine-containing compound metabolic process

ACACB TPI1 ACACA

2.29e-0365293GO:0072521
GeneOntologyBiologicalProcessamide biosynthetic process

ACACB ACACA

2.39e-0317292GO:0043604
GeneOntologyBiologicalProcesssmall molecule biosynthetic process

ACACB TPI1 ACACA

2.54e-0367693GO:0044283
GeneOntologyBiologicalProcesssulfur compound biosynthetic process

ACACB ACACA

2.56e-0317892GO:0044272
GeneOntologyBiologicalProcessnucleotide metabolic process

ACACB TPI1 ACACA

2.63e-0368493GO:0009117
GeneOntologyBiologicalProcessnucleoside phosphate metabolic process

ACACB TPI1 ACACA

2.70e-0369193GO:0006753
GeneOntologyBiologicalProcessfatty acid biosynthetic process

ACACB ACACA

2.94e-0319192GO:0006633
GeneOntologyBiologicalProcessmonocarboxylic acid metabolic process

ACACB TPI1 ACACA

3.17e-0373193GO:0032787
GeneOntologyBiologicalProcesscarbohydrate derivative biosynthetic process

ACACB TPI1 ACACA

3.24e-0373693GO:1901137
GeneOntologyBiologicalProcesspyridine nucleotide metabolic process

ACACB TPI1

3.28e-0320292GO:0019362
GeneOntologyBiologicalProcessnicotinamide nucleotide metabolic process

ACACB TPI1

3.28e-0320292GO:0046496
GeneOntologyBiologicalProcessheart development

EOMES ACACB TNNI1

3.50e-0375793GO:0007507
GeneOntologyBiologicalProcesspyridine-containing compound metabolic process

ACACB TPI1

3.54e-0321092GO:0072524
GeneOntologyBiologicalProcessnucleobase-containing small molecule metabolic process

ACACB TPI1 ACACA

3.64e-0376793GO:0055086
GeneOntologyBiologicalProcessprotein homooligomerization

ACACB ACACA

4.02e-0322492GO:0051260
GeneOntologyBiologicalProcesspurine ribonucleotide biosynthetic process

ACACB ACACA

4.30e-0323292GO:0009152
GeneOntologyBiologicalProcessglucose metabolic process

ACACB TPI1

4.75e-0324492GO:0006006
GeneOntologyBiologicalProcessribonucleotide biosynthetic process

ACACB ACACA

4.86e-0324792GO:0009260
GeneOntologyBiologicalProcessribose phosphate biosynthetic process

ACACB ACACA

5.10e-0325392GO:0046390
GeneOntologyBiologicalProcessmonocarboxylic acid biosynthetic process

ACACB ACACA

5.38e-0326092GO:0072330
GeneOntologyBiologicalProcessketone metabolic process

ACACB TPI1

6.16e-0327992GO:0042180
GeneOntologyBiologicalProcesspurine nucleotide biosynthetic process

ACACB ACACA

6.21e-0328092GO:0006164
GeneOntologyBiologicalProcesshexose metabolic process

ACACB TPI1

6.38e-0328492GO:0019318
DomainACC_central

ACACB ACACA

3.15e-072112PF08326
DomainAcCoA_COase_cen

ACACB ACACA

3.15e-072112IPR013537
DomainCOA_CT_CTER

ACACB ACACA

1.89e-064112PS50989
DomainCarboxyl_trans

ACACB ACACA

1.89e-064112IPR000022
DomainCOA_CT_NTER

ACACB ACACA

1.89e-064112PS50980
DomainCOA_CT_N

ACACB ACACA

1.89e-064112IPR011762
DomainCOA_CT_C

ACACB ACACA

1.89e-064112IPR011763
DomainCarboxyl_trans

ACACB ACACA

1.89e-064112PF01039
DomainBIOTIN

ACACB ACACA

3.15e-065112PS00188
DomainCPSASE_1

ACACB ACACA

3.15e-065112PS00866
DomainBC

ACACB ACACA

3.15e-065112PS50979
DomainBiotin_carb_C

ACACB ACACA

3.15e-065112SM00878
DomainBiotin_carb_C

ACACB ACACA

3.15e-065112PF02785
DomainBiotin_BS

ACACB ACACA

3.15e-065112IPR001882
DomainBiotin_COase_C

ACACB ACACA

3.15e-065112IPR005482
DomainBiotin_carboxylation_dom

ACACB ACACA

3.15e-065112IPR011764
DomainRudment_hybrid_motif

ACACB ACACA

4.72e-066112IPR011054
DomainCPSASE_2

ACACB ACACA

4.72e-066112PS00867
DomainBiotin_carb_N

ACACB ACACA

6.61e-067112PF00289
DomainCPSase_L_D2

ACACB ACACA

6.61e-067112PF02786
DomainCbamoylP_synth_lsu-like_ATP-bd

ACACB ACACA

6.61e-067112IPR005479
DomainBC-like_N

ACACB ACACA

6.61e-067112IPR005481
DomainTCEAL1

TCEAL6 TCEAL3

1.13e-059112IPR010370
DomainBiotin_lipoyl

ACACB ACACA

1.13e-059112PF00364
DomainBiotin_lipoyl

ACACB ACACA

1.42e-0510112IPR000089
DomainBIOTINYL_LIPOYL

ACACB ACACA

1.42e-0510112PS50968
DomainSingle_hybrid_motif

ACACB ACACA

2.07e-0512112IPR011053
Domain-

ACACB ACACA

2.45e-05131123.40.50.20
DomainPreATP-grasp_dom

ACACB ACACA

2.86e-0514112IPR016185
DomainATP_GRASP

ACACB ACACA

2.86e-0514112PS50975
DomainBEX

TCEAL6 TCEAL3

2.86e-0514112PF04538
DomainTF_A-like/BEX

TCEAL6 TCEAL3

2.86e-0514112IPR021156
DomainATP-grasp

ACACB ACACA

2.86e-0514112IPR011761
Domain-

ACACB ACACA

3.30e-05151123.30.1490.20
Domain-

ACACB ACACA

4.80e-05181123.30.470.20
DomainATP_grasp_subdomain_1

ACACB ACACA

4.80e-0518112IPR013815
Domain-

ACACB ACACA

6.58e-05211123.90.226.10
DomainClpP/crotonase-like_dom

ACACB ACACA

6.58e-0521112IPR029045
DomainATP_grasp_subdomain_2

ACACB ACACA

1.45e-0431112IPR013816
PathwayREACTOME_CHREBP_ACTIVATES_METABOLIC_GENE_EXPRESSION

ACACB ACACA

1.01e-05892M26991
PathwayWP_BIOTIN_METABOLISM_INCLUDING_IMDS

ACACB ACACA

1.30e-05992M40064
PathwayWP_CLEAR_CELL_RENAL_CELL_CARCINOMA_PATHWAYS

ACACB TPI1 ACACA

1.79e-058693M39375
PathwayREACTOME_BIOTIN_TRANSPORT_AND_METABOLISM

ACACB ACACA

1.99e-051192M27086
PathwayREACTOME_BIOTIN_TRANSPORT_AND_METABOLISM

ACACB ACACA

1.99e-051192MM14764
PathwayREACTOME_CARNITINE_METABOLISM

ACACB ACACA

3.28e-051492M27098
PathwayREACTOME_CARNITINE_METABOLISM

ACACB ACACA

3.28e-051492MM14788
PathwayWP_HEREDITARY_LEIOMYOMATOSIS_AND_RENAL_CELL_CARCINOMA_PATHWAY

ACACB ACACA

6.84e-052092M39751
PathwayWP_FATTY_ACID_BIOSYNTHESIS

ACACB ACACA

8.31e-052292M39440
PathwayWP_FATTY_ACID_BIOSYNTHESIS

ACACB ACACA

9.10e-052392MM15885
PathwayKEGG_PROPANOATE_METABOLISM

ACACB ACACA

1.89e-043392M4086
PathwayKEGG_PYRUVATE_METABOLISM

ACACB ACACA

2.79e-044092M7934
PathwayREACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP

ACACB ACACA

3.08e-044292M27172
PathwayREACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF

ACACB ACACA

5.29e-045592M27001
PathwayWP_AMPACTIVATED_PROTEIN_KINASE_SIGNALING

ACACB ACACA

7.84e-046792M39630
PathwayWP_LEPTIN_SIGNALING

ACACB ACACA

1.01e-037692M39491
PathwayWP_7Q1123_COPY_NUMBER_VARIATION_SYNDROME

ACACB ACACA

1.95e-0310692M40052
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

ACACB ACACA

2.02e-0310892M17034
PathwayWP_VEGFAVEGFR2_SIGNALING

ACACB MAP2K7 ACACA

2.08e-0343193M39729
PathwayREACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS

ACACB ACACA

2.49e-0312092MM14771
PathwayREACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS

ACACB ACACA

2.78e-0312792M27093
PathwayKEGG_INSULIN_SIGNALING_PATHWAY

ACACB ACACA

3.23e-0313792M18155
PathwayWP_ENDODERM_DIFFERENTIATION

EOMES ACACA

3.51e-0314392M39591
PathwayWP_MESODERMAL_COMMITMENT_PATHWAY

EOMES ACACA

4.01e-0315392M39546
PathwayREACTOME_METABOLISM_OF_STEROIDS

ACACB ACACA

4.06e-0315492M27832
PathwayREACTOME_FATTY_ACID_METABOLISM

ACACB ACACA

4.92e-0317092MM15573
PathwayREACTOME_FATTY_ACID_METABOLISM

ACACB ACACA

5.27e-0317692M27854
PathwayREACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS

ACACB ACACA

6.05e-0318992MM14772
PathwayREACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS

ACACB ACACA

6.62e-0319892M18311
PathwayWP_IL18_SIGNALING

ACACB MAP2K7

1.23e-0227392M39818
Pubmed

Blocking AMPK signalling to acetyl-CoA carboxylase increases cisplatin-induced acute kidney injury and suppresses the benefit of metformin.

ACACB ACACA

9.09e-08211236076520
Pubmed

De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.

ACACB ACACA

9.09e-08211225282359
Pubmed

AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation.

ACACB ACACA

9.09e-08211225001074
Pubmed

Acetyl-CoA carboxylase rewires cancer metabolism to allow cancer cells to survive inhibition of the Warburg effect by cetuximab.

ACACB ACACA

9.09e-08211227693630
Pubmed

AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis.

ACACB ACACA

9.09e-08211229433631
Pubmed

Structure and regulation of acetyl-CoA carboxylase genes of metazoa.

ACACB ACACA

9.09e-08211215749055
Pubmed

The subcellular localization of acetyl-CoA carboxylase 2.

ACACB ACACA

9.09e-08211210677481
Pubmed

Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival.

ACACB ACACA

9.09e-08211228290443
Pubmed

Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.

ACACB ACACA

9.09e-08211232215608
Pubmed

Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma.

ACACB ACACA

9.09e-08211230244972
Pubmed

Hormonal regulation of acetyl-CoA carboxylase isoenzyme gene transcription.

ACACB ACACA

9.09e-08211220139635
Pubmed

Activity and structure of human acetyl-CoA carboxylase targeted by a specific inhibitor.

ACACB ACACA

9.09e-08211229772612
Pubmed

Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and De Novo Lipogenesis of EGFRvIII Human Glioblastoma Cells.

ACACB ACACA

9.09e-08211228081256
Pubmed

Susceptibility of podocytes to palmitic acid is regulated by fatty acid oxidation and inversely depends on acetyl-CoA carboxylases 1 and 2.

ACACB ACACA

9.09e-08211224338821
Pubmed

Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin.

ACACB ACACA

9.09e-08211229976587
Pubmed

Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.

ACACB ACACA

9.09e-08211226976583
Pubmed

Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation.

ACACB ACACA

9.09e-08211224944901
Pubmed

Differential activation of recombinant human acetyl-CoA carboxylases 1 and 2 by citrate.

ACACB ACACA

2.73e-07311218455495
Pubmed

Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.

ACACB ACACA

2.73e-07311228877461
Pubmed

AMPK activation by SC4 inhibits noradrenaline-induced lipolysis and insulin-stimulated lipogenesis in white adipose tissue.

ACACB ACACA

2.73e-07311234668531
Pubmed

Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis.

ACACB ACACA

2.73e-07311220457939
Pubmed

Acetyl-CoA carboxylase 1 and 2 inhibition ameliorates steatosis and hepatic fibrosis in a MC4R knockout murine model of nonalcoholic steatohepatitis.

ACACB ACACA

2.73e-07311231990961
Pubmed

AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation.

ACACB ACACA

2.73e-07311230018077
Pubmed

Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism.

ACACB ACACA

2.73e-07311236417534
Pubmed

The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels.

ACACB ACACA

2.73e-07311227381369
Pubmed

Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice.

ACACB ACACA

2.73e-07311217210641
Pubmed

Acetyl-coenzyme A carboxylase alpha gene variations may be associated with the direct effects of some antipsychotics on triglyceride levels.

ACACB ACACA

2.73e-07311219846279
Pubmed

Exploring genetic variations that may be associated with the direct effects of some antipsychotics on lipid levels.

ACACB ACACA

2.73e-07311218031993
Pubmed

Specific pattern of LKB1 and phospho-acetyl-CoA carboxylase protein immunostaining in human normal tissues and lung carcinomas.

ACACB ACACA

2.73e-07311217521700
Pubmed

Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation.

ACACB ACACA

2.73e-07311228768177
Pubmed

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.

ACACB ACACA

5.45e-07411224185692
Pubmed

Crystal structure of Spot 14, a modulator of fatty acid synthesis.

ACACB ACACA

5.45e-07411220952656
Pubmed

Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability.

ACACB ACACA

5.45e-07411238447582
Pubmed

Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program.

ACACB ACACA

9.09e-07511237163372
Pubmed

Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss.

ACACB ACACA

9.09e-07511232694673
Pubmed

TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.

ACACB ACACA

9.09e-07511216794074
Pubmed

The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations.

ACACB ACACA

2.54e-06811236001969
Pubmed

SIRT1 regulates Tat-induced HIV-1 transactivation through activating AMP-activated protein kinase.

ACACB ACACA

4.09e-061011219720090
Pubmed

HDAC1/NFκB pathway is involved in curcumin inhibiting of Tat-mediated long terminal repeat transactivation.

ACACB ACACA

5.99e-061211221344388
Pubmed

AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress.

ACACB ACACA

5.99e-061211221436046
Pubmed

Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex.

EOMES MAP2K7

1.39e-051811222090513
Pubmed

AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development.

ACACB ACACA

1.90e-052111219217427
Pubmed

Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).

ACACB ACACA

2.09e-052211220965718
Pubmed

ATP-citrate lyase deficiency in the mouse.

ACACB ACACA

2.29e-052311214662765
Pubmed

Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events.

TCEAL6 TCEAL3

2.50e-052411216221301
Pubmed

Mapping the mammalian ribosome quality control complex interactome using proximity labeling approaches.

ACACB MAP2K7 ACACA

3.08e-0520211329540532
Pubmed

A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice.

TCEAL6 TCEAL3

3.42e-052811223677977
Pubmed

WWP2 is an E3 ubiquitin ligase for PTEN.

ACACB ACACA

3.68e-052911221532586
Pubmed

Inceptor counteracts insulin signalling in β-cells to control glycaemia.

ACACB ACACA

5.07e-053411233505018
Pubmed

LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation.

ACACB ACACA

5.07e-053411226378152
Pubmed

A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice.

TPI1 ACACA

6.70e-053911233059001
Pubmed

Proteomic analysis of HIV-1 Gag interacting partners using proximity-dependent biotinylation.

ACACB ACACA

7.78e-054211226362536
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

ACACB TPI1 ACACA

1.66e-0435711337059091
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

ACACB AKAP8L TPI1

2.26e-0439611326687479
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ACACB AKAP8L ACACA

2.65e-0441811334709266
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ACACB AKAP8L ACACA

2.70e-0442111336976175
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

ACACB AKAP8L TPI1 ACACA

3.14e-04113911436417873
InteractionNPTXR interactions

ACACB ACACA

6.19e-052792int:NPTXR
InteractionARL10 interactions

ACACB TPI1 ACACA

6.54e-0518993int:ARL10
InteractionKATNAL2 interactions

AKAP8L ACACA

6.66e-052892int:KATNAL2
InteractionSLX4 interactions

ACACB AKAP8L TPI1 ACACA

7.22e-0557294int:SLX4
InteractionLTN1 interactions

ACACB MAP2K7 ACACA

7.86e-0520193int:LTN1
InteractionPRKAA2 interactions

ACACB AKAP8L ACACA

1.36e-0424293int:PRKAA2
InteractionTRIB1 interactions

MAP2K7 ACACA

1.82e-044692int:TRIB1
InteractionCDK17 interactions

ACACB ACACA

3.41e-046392int:CDK17
InteractionTHRSP interactions

ACACB ACACA

3.63e-046592int:THRSP
InteractionPHF21A interactions

ACACB AKAP8L ACACA

3.80e-0434393int:PHF21A
InteractionMID1IP1 interactions

ACACB ACACA

4.58e-047392int:MID1IP1
CytobandEnsembl 112 genes in cytogenetic band chrXq22

TCEAL6 TCEAL3

7.51e-04172112chrXq22
CytobandEnsembl 112 genes in cytogenetic band chr19p13

AKAP8L MAP2K7

1.49e-02797112chr19p13
GeneFamilyTranscription elongation factor A like family

TCEAL6 TCEAL3

4.62e-069721216
CoexpressionDESCARTES_ORGANOGENESIS_CARDIAC_MUSCLE_LINEAGES

ACACB TPI1 TNNI1

5.22e-05182113MM3637
CoexpressionGSE3982_EOSINOPHIL_VS_MAST_CELL_UP

ACACB MAP2K7 SAMSN1

6.80e-05199113M5397
CoexpressionGSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_UP

EOMES SAMSN1 TNNI1

6.90e-05200113M5610
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Neuron|GW16 / Sample Type, Dataset, Time_group, and Cell type.

EOMES MAP2K7

4.41e-0412911264768adf23123b92280fb30eb85147cbee084ae0
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TCEAL3 TNNI1

4.83e-041351125b13ff740d9f7d96274aebb6b389a80f6004adc7
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-MAIT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EOMES SAMSN1

5.88e-04149112f4bee5fdaaa4a1917e403de90e5a62353006df24
ToppCellfacs-MAT-Fat-3m-Lymphocytic-NK_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

6.27e-04154112391d40ef902773ffe832a50a14d35d31c56d3723
ToppCellfacs-Heart-RA-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

6.35e-04155112cc3fc379ea78742a216317054f336331f7c7a157
ToppCellfacs-Heart-RA-24m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

6.35e-041551121900a76754e2a9c7117e531c5907b7942f72c4a6
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

6.35e-0415511293513bab53b40e9c3c91ab8e3316ea00a4f66cd2
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EOMES TNNI1

6.44e-0415611233deda19f06172079ef1dd49fd54d66da1e7fb14
ToppCellT_cells-GNLY+GZMB+_T_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

EOMES SAMSN1

6.52e-04157112e9eb56a1dd96bd2e9725a20f2cf70ddeab811bd6
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TNNI1

6.60e-041581128844fba9c1e41f062edf3110d025f33b86afb951
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TNNI1

6.60e-04158112c56607cba9a3719ac6d573d970686053e1676985
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TCEAL6 TCEAL3

6.77e-041601128624f101828efd32cdd38a65df8d94d690720a63
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TCEAL6 TCEAL3

6.77e-041601129de3dd6b9d4b51314d60b3b01f4132bcfa2dfc18
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TNNI1

6.85e-04161112334f540dff3508d451e5e85e8e4e8f3b8d6b74e7
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TNNI1

6.85e-0416111281d44438e4be4e68a59247e62f02026301a8a0c5
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TNNI1

6.94e-0416211204a96442e0fcdb6a65b9e45044021677f9f53d38
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TNNI1

6.94e-041621127adb3e279526e1f21033c10af0a0058258f21842
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TNNI1

7.02e-04163112d18fee517e0daed51f89703f94f218567c83cb03
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TNNI1

7.02e-04163112f4a6e28ad3c1fcbf62ed9b2bf09f65d2ab0b31d1
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TNNI1

7.11e-041641129fed5df40f50bde35db8bf89c291cbdc0e104112
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TNNI1

7.11e-04164112e712d6b89461f741dbd773ba9a27ecaddf97cbaa
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EOMES SAMSN1

7.19e-04165112004d793bf5bb6fb3b7bf38baf11b32d46375fe4d
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACB ACACA

7.19e-04165112d449a568664a81d9b5538e8f409301448a32ac37
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TNNI1

7.19e-041651128741df8066a44c841752a99ad306d26ea68f5344
ToppCellfacs-Heart-RV-3m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

7.28e-04166112c0fd3f3f5c3412746da279b856af0d28b9b70c5d
ToppCellfacs-Heart-RV-3m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

7.28e-0416611233c4876df43b4c1d100699bca47459918bd054d6
ToppCellfacs-Heart-RV-3m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

7.28e-04166112ac9b9df57d65ccbbf9ae3add50c5663efcd30dcb
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TNNI1

7.37e-04167112aef22535a76e93472bcedacbb2c6991f3c9c8cd5
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EOMES SAMSN1

7.37e-0416711284551ee71f9d8d03d514711fc7ca4422c810140b
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TCEAL6 TNNI1

7.37e-0416711291b14df450bfb6a2b406c88f8c75cd51eeb9e82b
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SAMSN1 TNNI1

7.46e-041681126dd58fd981750da49afd53796f244e1803cce97f
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TCEAL3 TNNI1

7.63e-04170112cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCEAL6 TNNI1

7.63e-0417011260bbd738c12e64e483485586c30057304884f5a6
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

7.63e-041701127040f7b1e4d8d26db787449e557371c5d872c95a
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TCEAL3 TNNI1

7.63e-04170112da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-NK_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EOMES SAMSN1

7.72e-04171112f16cb64b8844c2668922c786888efaa9f873afcc
ToppCellfacs-Spleen-nan-24m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TPI1

7.90e-04173112e07e126e9dac6f1160cb3191d2e8374f39155d0d
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEAL6 ACACA

7.90e-041731128bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEAL6 ACACA

7.90e-041731123e3c61468e703330788a10d850ef41a85680f86d
ToppCell367C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

EOMES TCEAL3

7.90e-041731125d3c917e4d0de3158550a8ab2006ddfa87159ffa
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SAMSN1 TNNI1

7.99e-0417411216204ff504b7b382b4d90ca35003ad5336020e07
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EOMES SAMSN1

8.09e-0417511224f07bc6583129835bc67c04dabf5e82f6b8c369
ToppCellfacs-Trachea-nan-18m-Lymphocytic|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

8.18e-041761129dd862dcee6947a53189728f6b4cd40e7b67cb71
ToppCellfacs-Trachea-nan-18m-Lymphocytic-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

8.18e-0417611214c6c3fdb53f9dfc02b951bc955b90213110c089
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

8.18e-04176112dff11730f26b4b7d26ee83b665d0284bc847cac0
ToppCellfacs-Trachea-nan-18m-Lymphocytic-T_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

8.18e-04176112d990e7af8120210100d13caa0465b27cf77a451a
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TCEAL3 TNNI1

8.27e-041771127ebdcedfe02da6d05bba3d625d8bd4c4ea96e4ad
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-mature_NK_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TCEAL3

8.27e-041771126561794ae3b14b5279b249eb5e93b80ef15ed82c
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

8.27e-0417711231201a72b7c1bdb0eff892b7072a35c80fd34727
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TCEAL3 TNNI1

8.27e-04177112c9b02a2e1ff2aa18c37e88a53b06a5b696a442ae
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

8.27e-0417711289d0131320cd96af8b0ee54f0f4d4771d17ef44e
ToppCell15-Airway-Immune-Hematopoietic,_Natural_Killer_Cell|Airway / Age, Tissue, Lineage and Cell class

EOMES SAMSN1

8.36e-041781120003c3f2561b7a1fd86772bcba59883ba1f17cd2
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

8.36e-0417811200a5d8f47373be4792bf53914db63a1aedc2d77a
ToppCelldroplet-Marrow-BM-1m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TNNI1

8.55e-04180112ff34195bb7325e61fbf823c103c5e6115d8f1248
ToppCellfacs-Trachea-18m-Hematologic-lymphocytic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EOMES SAMSN1

8.55e-04180112c35cf2510183c09688453b12e721d264cf57caad
ToppCellfacs-Heart-RA-18m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

8.55e-041801129be0af61d496a29d737bb772ad09864797994299
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TCEAL6

8.55e-041801123d54cc767e25d91ed2203d8a03e5bf5e15f21699
ToppCellRA-11._Adipocyte|RA / Chamber and Cluster_Paper

ACACB ACACA

8.55e-04180112d48a3d27357f7d184132a6805950f93080146b59
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TCEAL6 TNNI1

8.55e-04180112d685fa2b013bc085dbef7c40956ed3043f83e483
ToppCellfacs-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACB TNNI1

8.55e-0418011272310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCellfacs-Trachea-18m-Hematologic-lymphocytic-T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EOMES SAMSN1

8.64e-041811127875fe64ec500a925245ab50cffd6890eabaea8c
ToppCellfacs-Trachea-18m-Hematologic-lymphocytic-T_cell-T_cell_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EOMES SAMSN1

8.64e-04181112a23b2e12bc133166e3ed45ab7116f74afbca6eec
ToppCellLV-17._Lymphocyte|LV / Chamber and Cluster_Paper

EOMES SAMSN1

8.64e-0418111281fafa69c8c240250a667a5f3b321e8be1b9a288
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCEAL6 TNNI1

8.74e-04182112cde8fa4f42d25545abaa9ee885b4b1e24a5a8e08
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TCEAL6 TPI1

8.74e-04182112fa16e194f04250149c82e86551270b244cbc8af4
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EOMES SAMSN1

8.74e-0418211209d0793245d3d77ab5fc384c0b62637f736da50b
ToppCellControl-Lymphocytic_NKT-iNKT/MAIT|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EOMES SAMSN1

8.83e-0418311259e8d07556390828f7557ba3fd2f7d49851498b7
ToppCellLA-11._Adipocyte|World / Chamber and Cluster_Paper

ACACB ACACA

8.83e-04183112b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

ACACB ACACA

8.83e-041831123f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellControl-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EOMES SAMSN1

8.83e-041831122c5707ada3442eb7100a2a5f9438d5a2ac53a9e1
ToppCelldroplet-Limb_Muscle-nan-21m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

8.83e-04183112ac70a6ec9270b1bfe089702262d4575a6c42afb4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES TCEAL6

8.93e-041841127d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCellHealthy/Control-CD4+_CTL|Healthy/Control / Disease group and Cell class

EOMES SAMSN1

8.93e-041841126c6ffa150f81e456f88e9065de90c2dcda417589
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SAMSN1 TPI1

8.93e-0418411216ba6822570b1017b8f24d9439b4fbdaaeecf7aa
ToppCellfacs-Marrow|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAMSN1 TPI1

9.03e-04185112e40f0a0439834c3025d6c7832977be4e37a94c44
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SAMSN1 TNNI1

9.03e-0418511248de4d9fad55077732bf64eca4919103ecbc1512
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

9.03e-04185112212a8f6fb9eac0c6a89a20a9aa30d48c21abd375
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic_-_developing-DN1_thymic_pro-T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EOMES SAMSN1

9.03e-041851125db31631a4b4c4bfeb28f02d8dab00a48d77bcba
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-NK_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EOMES SAMSN1

9.12e-04186112885aed2472cead81d60c9f3a28c0ff10eb449592
ToppCell3'-Adult-LargeIntestine-Hematopoietic-T_cells-NK_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EOMES SAMSN1

9.12e-04186112e083356f72995645f873ca0157d56bea5e942044
ToppCelldroplet-Limb_Muscle-nan-24m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

9.12e-04186112c5a27a128677aa04154eb78402d01fed149875de
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCEAL6 TNNI1

9.12e-041861121094c7140131454b2583200e1c01e81ccab3db23
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_natural_killer_[NK]_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EOMES SAMSN1

9.22e-04187112b5c8322ee728303425be677aa0c36fa552fd0f59
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EOMES SAMSN1

9.32e-04188112624426815b789f0f35c327b8c3c0c05ba3aa7d98
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TCEAL6 TNNI1

9.32e-041881129db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCellILEUM-non-inflamed-(5)_Plasma-(5)_IgG_plasma_cells|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

AKAP8L SAMSN1

9.32e-041881122156f1bc849ff1cb09ae296d13bedd913ae6b43b
ToppCelldroplet-Mammary_Gland-nan-21m-Lymphocytic-T_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

9.32e-041881127ed1f1be4d9e653cfcd70a761ddc2ab9dc8f0a3f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TCEAL6 TNNI1

9.32e-04188112047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCelldroplet-Mammary_Gland-nan-21m-Lymphocytic-T_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES SAMSN1

9.32e-041881122598077d94b09cde8605c7074e1fedcfbca7a9ce
ToppCellRA-11._Adipocyte|World / Chamber and Cluster_Paper

ACACB ACACA

9.32e-041881124dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCell10x_3'_v3-spleen_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EOMES SAMSN1

9.42e-041891120fe8901e10c619c93b7788792da1706a32102c6e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TCEAL6 TNNI1

9.52e-0419011292710caaff05123cf8e909319d7ac441d9b31a66
ToppCellfacs-Lung-nan-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEAL6 TCEAL3

9.52e-04190112834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCellrenal_medulla_nuclei-Adult_normal_reference|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

ACACB ACACA

9.52e-04190112f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCellPCW_07-8.5-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_natural_killer_[NK]_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

EOMES SAMSN1

9.52e-041901125c6801046ab88aad76697984342319872a8f9e38
ToppCellfacs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEAL6 TCEAL3

9.52e-04190112c7bd087f36321cec61b98657433b4d19d135791f
ToppCellCOVID-19-Heart-T_cell|Heart / Disease (COVID-19 only), tissue and cell type

EOMES SAMSN1

9.52e-04190112e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TCEAL3 TPI1

9.52e-04190112422f58447e2b308f6f9dad822c4600c78e571c5d
ToppCellPCW_10-12-Immune_Lymphocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EOMES SAMSN1

9.52e-041901129b56763d62e1ed50006a5b90b160c5a82aab515b
ToppCellmetastatic_Lymph_Node-T/NK_cells-Exhausted_CD8+_T|metastatic_Lymph_Node / Location, Cell class and cell subclass

EOMES SAMSN1

9.52e-04190112cb4cf8ae2156c20b7978ae2e55aa605b4e90f455
ComputationalSteroid hormone receptors and binding proteins.

ACACB ACACA

1.17e-042672MODULE_404
Drug6,8-diallyl 5,7-dihydroxy 2-(2-allyl 3-hydroxy 4-methoxyphenyl)1-H benzo(b)pyran-4-one

ACACB ACACA

3.18e-066112ctd:C438505
DrugBiotin

ACACB ACACA

7.63e-069112DB00121
Drugisosteviol

ACACB ACACA

1.40e-0512112ctd:C515747
DrugB-OH

TPI1 ACACA

5.34e-0523112CID000008017
DrugDietary Carbohydrates

ACACB AKAP8L ACACA

8.85e-05189113ctd:D004040
DrugEsculin Hydrate [531-75-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A

ACACB MAP2K7 SAMSN1

1.00e-041971135411_UP
Drugipratropium bromide

TPI1 ACACA

2.17e-0446112CID000003746
Drugtaurine-ursodeoxycholate conjugate

ACACB ACACA

2.17e-0446112ctd:C030141
Drugmuconic acid

TPI1 TNNI1

2.46e-0449112CID000000310
DrugMethamphetamine

ACACB AKAP8L MAP2K7 TPI1 TNNI1

2.96e-041401115ctd:D008694
DrugFatty Acids, Essential

ACACB ACACA

3.58e-0459112ctd:D005228
Drugbufalin

MAP2K7 TPI1

3.82e-0461112ctd:C022777
Drugpalladium

TPI1 ACACA

4.75e-0468112CID000023938
Drugtrovafloxacin

MAP2K7 TPI1 ACACA

6.43e-04371113ctd:C080163
DrugAristolochic Acids

ACACB ACACA

8.12e-0489112ctd:D034341
Drug32 P

TPI1 TNNI1 ACACA

8.29e-04405113CID000448772
DrugFatty Acids, Omega-3

ACACB ACACA

9.83e-0498112ctd:D015525
Drugphosphatidate

SAMSN1 TPI1 ACACA

9.99e-04432113CID005460104
DrugAICA ribonucleotide

ACACB ACACA

1.06e-03102112ctd:C031143
DrugTO-901317

ACACB ACACA

1.15e-03106112ctd:C423915
DrugEndocrine Disruptors

TPI1 ACACA

1.24e-03110112ctd:D052244
Drugrhombic

EOMES ACACA

1.28e-03112112CID000018879
DrugNaBu

TNNI1 ACACA

1.52e-03122112CID000052923
DrugAC1Q6RZ4

TPI1 ACACA

1.54e-03123112CID000000719
Drugethylene dichloride

ACACB TCEAL3 ACACA

1.89e-03539113ctd:C024565
Diseasemuscular disease (implicated_via_orthology)

ACACB ACACA

8.27e-07592DOID:0080000 (implicated_via_orthology)
Diseasefatty liver disease (implicated_via_orthology)

ACACB ACACA

3.83e-053192DOID:9452 (implicated_via_orthology)
Diseaseheart disease (implicated_via_orthology)

MAP2K7 TNNI1

5.78e-053892DOID:114 (implicated_via_orthology)
Diseasenon-alcoholic fatty liver disease (biomarker_via_orthology)

ACACB ACACA

1.70e-046592DOID:0080208 (biomarker_via_orthology)
DiseaseMyocardial Failure

MAP2K7 ACACA

4.87e-0411092C1959583
DiseaseHeart Failure, Right-Sided

MAP2K7 ACACA

4.87e-0411092C0235527
DiseaseLeft-Sided Heart Failure

MAP2K7 ACACA

4.87e-0411092C0023212
DiseaseCongestive heart failure

MAP2K7 ACACA

4.87e-0411092C0018802
DiseaseHeart failure

MAP2K7 ACACA

4.87e-0411092C0018801
DiseaseHeart Decompensation

MAP2K7 ACACA

4.87e-0411092C1961112
DiseaseHbA1c measurement

EOMES ACACB

1.69e-0267592EFO_0004541

Protein segments in the cluster

PeptideGeneStartEntry
AMAGWGGRGSYQRKM

EOMES

571

O95936
MVFANWRGFSGGMKD

ACACA

2041

Q13085
GFGNGMKQMRRTWKT

AKAP8L

251

Q9ULX6
LMIFANWRGFSGGMK

ACACB

2151

O00763
MGSGTCGQVWKMRFR

MAP2K7

126

O14733
SLRNGDVKGGFMKWM

OR1Q1

291

Q15612
GMWTGMLNNKVGNFK

SAMSN1

201

Q9NSI8
KQKMGGFHWMQRDVQ

TCEAL6

156

Q6IPX3
MAPSRKFFVGGNWKM

TPI1

1

P60174
WRKNVEAMSGMEGRK

TNNI1

161

P19237
KQKMGGFHWMQRDVQ

TCEAL3

156

Q969E4