Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE2 SYNE1 SUN1

1.26e-0552183GO:0140444
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH5 DNAH3 DNAH2 DNAH17

3.75e-05182184GO:0008569
GeneOntologyMolecularFunctionATP-dependent activity

ABCA3 SETX MYO5C SHOC1 ABCD2 DNAH5 DHX16 DNAH3 EP400 DDX52 ABCB5 DNAH2 ABCF2 ATP10A DICER1 MMAA IGHMBP2 DNAH17 AACS

4.69e-0561421819GO:0140657
GeneOntologyMolecularFunctionglucosamine-6-phosphate deaminase activity

GNPDA2 GNPDA1

1.19e-0422182GO:0004342
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH5 DNAH3 DNAH2 DNAH17

2.30e-04282184GO:0051959
GeneOntologyMolecularFunctionprotein kinase activity

TRPM6 DCAF1 ABL2 PDPK1 TYRO3 GRK2 PIK3CG FGFR3 PAK5 NEK7 ZAP70 PRKAA2 PRKCH LTK PSKH2 TOP1 MAP3K2

3.34e-0460021817GO:0004672
GeneOntologyMolecularFunctioncalcium ion binding

CAPN12 ADGRV1 ZZEF1 TBC1D8B RYR1 RYR2 NRXN1 NECAB1 FBLN7 CLXN S100A7L2 ANXA4 ITSN1 DUOX2 PLCD4 MYL12A EFHC2 MEGF8 AGRN

5.89e-0474921819GO:0005509
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH5 DNAH3 DNAH2 DNAH17

6.88e-04372184GO:0045505
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR2

7.02e-0442182GO:0005219
GeneOntologyMolecularFunctionphenylalanine-tRNA ligase activity

FARSA FARS2

7.02e-0442182GO:0004826
GeneOntologyMolecularFunctionkinase activity

TRPM6 DCAF1 ABL2 PDPK1 NME9 TYRO3 GRK2 PIK3CG PIP5K1B FGFR3 PAK5 NEK7 ZAP70 PRKAA2 PRKCH LTK PSKH2 TOP1 MAP3K2

7.47e-0476421819GO:0016301
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

TRPM6 DCAF1 ABL2 PDPK1 TYRO3 GRK2 PIK3CG PIP5K1B FGFR3 PAK5 NEK7 ZAP70 PRKAA2 PRKCH LTK PSKH2 TOP1 MAP3K2

8.13e-0470921818GO:0016773
GeneOntologyBiologicalProcessnegative regulation of programmed cell death

SYCP2L SETX ABL2 ASIC2 PDPK1 TYRO3 NAA35 GRK2 PIK3CG GLP1R NR1H4 CARD14 NGB PRAMEF19 SYNE1 ANXA4 ITSN1 PAK5 PRAMEF18 TEX11 CBS BBS10 PRKAA2 PRKCH LTK ARHGEF2 ENO1 DNAJC3 IL7

1.46e-05117121629GO:0043069
GeneOntologyBiologicalProcessnegative regulation of apoptotic process

SETX ABL2 ASIC2 PDPK1 TYRO3 NAA35 GRK2 PIK3CG GLP1R NR1H4 CARD14 NGB PRAMEF19 SYNE1 ANXA4 ITSN1 PAK5 PRAMEF18 TEX11 CBS BBS10 PRKAA2 PRKCH LTK ARHGEF2 ENO1 DNAJC3 IL7

2.17e-05113321628GO:0043066
GeneOntologyBiologicalProcessglucosamine metabolic process

GNPDA2 GNPDA1 OGT

2.21e-0562163GO:0006041
GeneOntologyBiologicalProcesspeptidyl-amino acid modification

ADCY10 ABL2 PDPK1 ZZEF1 NAA35 GRK2 NRXN1 NKTR FGFR3 TPST2 OGT NDUFAF5 RGPD8 NEK7 NSD1 CREBBP ZAP70 IL22 PRKAA2 PRKCH LTK ARHGEF2 AGRN TOP1 IL7

3.46e-0597621625GO:0018193
GeneOntologyCellularComponentsarcomere

ABRA SPTBN1 MYOZ2 RYR1 RYR2 ANKRD2 SYNE2 ANK3 SYNE1 MYL12A ENO1

6.46e-0524921811GO:0030017
GeneOntologyCellularComponentaxonemal dynein complex

DNAH5 DNAH3 DNAH2 DNAH17

1.23e-04252184GO:0005858
GeneOntologyCellularComponentmyofibril

ABRA SPTBN1 MYOZ2 RYR1 RYR2 ANKRD2 SYNE2 ANK3 SYNE1 MYL12A ENO1

1.46e-0427321811GO:0030016
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE2 SYNE1 SUN1

1.74e-04112183GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE2 SYNE1 SUN1

1.74e-04112183GO:0106094
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE2 SYNE1 SUN1

1.74e-04112183GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE2 SYNE1 SUN1

1.74e-04112183GO:0034993
GeneOntologyCellularComponentcontractile muscle fiber

ABRA SPTBN1 MYOZ2 RYR1 RYR2 ANKRD2 SYNE2 ANK3 SYNE1 MYL12A ENO1

2.46e-0429021811GO:0043292
GeneOntologyCellularComponentaxoneme

CFAP251 DNAH5 DNAH3 CLXN DNAH2 CFAP210 EFHC2 RP1L1 DNAH17

3.36e-042072189GO:0005930
GeneOntologyCellularComponentciliary plasm

CFAP251 DNAH5 DNAH3 CLXN DNAH2 CFAP210 EFHC2 RP1L1 DNAH17

3.48e-042082189GO:0097014
GeneOntologyCellularComponentcilium

ADCY10 PDE1A CFAP251 ADGRV1 PGAM1 GRK2 DNAH5 TNPO1 CACNA1F DNAH3 CLXN PRAMEF19 DNAH2 CFAP210 PRAMEF18 CFAP298 BBS10 EFHC2 CEP250 RP1L1 DNAH17

4.85e-0489821821GO:0005929
MousePhenoabnormal circulating total protein level

SPTBN1 GC PCNX2 NRXN1 DNAH5 ITSN1 SUN1 DUOX2 SLCO1B1 MYL12A MMAA MIGA2 LTK ARHGEF2

3.95e-0626916614MP:0011888
DomainEF-hand-dom_pair

CAPN12 CFAP251 ZZEF1 TBC1D8B RYR1 RYR2 NECAB1 CACNA1F CLXN S100A7L2 ITSN1 DUOX2 PLCD4 MYL12A EFHC2

1.33e-0628721615IPR011992
DomainEF_hand_dom

CAPN12 ZZEF1 TBC1D8B RYR1 RYR2 NECAB1 CLXN S100A7L2 ITSN1 DUOX2 PLCD4 MYL12A EFHC2

3.21e-0623221613IPR002048
Domain-

CAPN12 CFAP251 ZZEF1 TBC1D8B RYR1 RYR2 NECAB1 CLXN ITSN1 DUOX2 PLCD4 MYL12A EFHC2

1.15e-05261216131.10.238.10
DomainEF_HAND_2

CAPN12 ZZEF1 TBC1D8B RYR2 NECAB1 CLXN S100A7L2 ITSN1 DUOX2 PLCD4 MYL12A EFHC2

1.65e-0523121612PS50222
DomainAAA

ABCA3 ABCD2 DNAH5 DNAH3 ABCB5 DNAH2 ABCF2 MMAA IGHMBP2

4.62e-051442169SM00382
DomainAAA+_ATPase

ABCA3 ABCD2 DNAH5 DNAH3 ABCB5 DNAH2 ABCF2 MMAA IGHMBP2

4.62e-051442169IPR003593
DomainGlucosamine6P_isomerase_CS

GNPDA2 GNPDA1

1.33e-0422162IPR018321
DomainGlucosamine6P_isomerase

GNPDA2 GNPDA1

1.33e-0422162IPR004547
DomainGLC_GALNAC_ISOMERASE

GNPDA2 GNPDA1

1.33e-0422162PS01161
DomaintRNA-synt_2d

FARSA FARS2

1.33e-0422162PF01409
Domain-

ADCY10 ABCA3 SETX SAMD9 DAP3 ABCD2 RAB29 DNAH5 CARD14 DHX16 TPST2 DNAH3 EP400 DDX52 ABCB5 DNAH2 ABCF2 DICER1 URGCP MMAA IGHMBP2

1.60e-04746216213.40.50.300
DomainP-loop_NTPase

ADCY10 ABCA3 SETX SAMD9 MYO5C DAP3 ABCD2 RAB29 DNAH5 CARD14 DHX16 TPST2 DNAH3 EP400 DDX52 ABCB5 DNAH2 ABCF2 DICER1 URGCP MMAA IGHMBP2

3.49e-0484821622IPR027417
DomainPhenylalanyl-tRNA_Synthase

FARSA FARS2

3.96e-0432162IPR002319
DomainRyanodine_rcpt

RYR1 RYR2

3.96e-0432162IPR003032
DomainRyanrecept_TM4-6

RYR1 RYR2

3.96e-0432162IPR009460
DomainRyR

RYR1 RYR2

3.96e-0432162PF02026
DomainRR_TM4-6

RYR1 RYR2

3.96e-0432162PF06459
DomainRyan_recept

RYR1 RYR2

3.96e-0432162IPR013333
DomainProtein_kinase_ATP_BS

ABL2 PDPK1 TYRO3 GRK2 FGFR3 PAK5 NEK7 ZAP70 PRKAA2 PRKCH LTK PSKH2 MAP3K2

4.91e-0437921613IPR017441
DomainDynein_heavy_chain_D4_dom

DNAH5 DNAH3 DNAH2

5.05e-04142163IPR024317
DomainDynein_HC_stalk

DNAH5 DNAH3 DNAH2

5.05e-04142163IPR024743
DomainDynein_heavy_dom-2

DNAH5 DNAH3 DNAH2

5.05e-04142163IPR013602
DomainDHC_N2

DNAH5 DNAH3 DNAH2

5.05e-04142163PF08393
DomainATPase_dyneun-rel_AAA

DNAH5 DNAH3 DNAH2

5.05e-04142163IPR011704
DomainMT

DNAH5 DNAH3 DNAH2

5.05e-04142163PF12777
DomainAAA_8

DNAH5 DNAH3 DNAH2

5.05e-04142163PF12780
DomainAAA_5

DNAH5 DNAH3 DNAH2

5.05e-04142163PF07728
DomainEFh

ZZEF1 RYR2 NECAB1 CLXN ITSN1 DUOX2 PLCD4 MYL12A

5.13e-041582168SM00054
DomainDHC_fam

DNAH5 DNAH3 DNAH2

6.26e-04152163IPR026983
DomainDynein_heavy

DNAH5 DNAH3 DNAH2

6.26e-04152163PF03028
DomainDynein_heavy_dom

DNAH5 DNAH3 DNAH2

6.26e-04152163IPR004273
DomainEF_HAND_1

CAPN12 TBC1D8B NECAB1 CLXN S100A7L2 ITSN1 DUOX2 PLCD4 MYL12A

6.32e-042042169PS00018
DomainC2_dom

CPNE8 FER1L6 PIK3CG ITSN1 PLCD4 SYTL5 PRKCH TNS1

6.56e-041642168IPR000008
DomainKASH

SYNE2 SYNE1

7.87e-0442162IPR012315
DomainKASH

SYNE2 SYNE1

7.87e-0442162PS51049
DomainKASH

SYNE2 SYNE1

7.87e-0442162SM01249
DomainKASH

SYNE2 SYNE1

7.87e-0442162PF10541
DomainGlc/Gal-6P_isomerase

GNPDA2 GNPDA1

7.87e-0442162IPR006148
DomainGlucosamine_iso

GNPDA2 GNPDA1

7.87e-0442162PF01182
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SPTBN1 NOL6 NCBP1 FAM98B PGAM1 RYR2 FER1L6 DAP3 PXDN MIA2 NRXN1 SYNE2 RGPD5 RGPD8 COPA DDX52 SYNE1 ABCB5 ITSN1 DNAH2 DUOX2 ABCF2 CFAP210 SLC4A3 GSTK1 SEC23IP OGDHL ARHGEF2 ENO1 DNAJC3 TOP1 STAG2 DOP1A

2.19e-1014422223335575683
Pubmed

A human MAP kinase interactome.

SETX ABL2 SPTBN1 SREBF2 ARHGEF11 NKTR ANK3 SYNE1 ITSN1 PAK5 LAMA3 CREBBP CEP250 ANKRD17 PRKCH TNS1 MAP3K2

1.88e-084862221720936779
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

ABL2 SPTBN1 GRK2 PXDN KCNJ4 SHOC1 FGFR3 DNAH5 COPA ITSN1 NSD1 LARS2 CREBBP ARHGEF2

3.56e-083322221437433992
Pubmed

The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.

SYNE2 SYNE1 SUN1

2.57e-073222316079285
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MYCBP2 SPTBN1 ARHGEF11 FARSA NRXN1 KCNJ4 SYNE2 AMPD2 OGT RGPD8 ANK3 FXR2 SYNE1 ITSN1 PAK5 NSD1 SEC23IP ANKRD17 ARHGEF2 ENO1 TNS1 AGRN

2.88e-079632222228671696
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TRPM6 SPTBN1 NOL6 NCBP1 PGAM1 DAP3 FARSA SCFD1 DNAH5 TMEM117 DHX16 TNPO1 COPA DDX52 SYNE1 DUOX2 ABCF2 CBS DICER1 MYL12A PAXBP1 PRKAA2 SEC23IP ZC3HAV1L ENO1 TOP1 STAG2

4.94e-0714252222730948266
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TRPM6 SETX SPTBN1 SREBF2 METTL17 TNPO1 AMPD2 OGT ANK3 PRAMEF19 DDX52 ITSN1 SUN1 NSD1 PRAMEF18 PAXBP1 ANKRD17 OGDHL TNS1 GEN1 HERC4 AGRN STAG2

5.50e-0710842222311544199
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

CHST14 SREBF2 NAA35 FARSA PXDN SCFD1 TNPO1 AMPD2 COPA DDX52 SUN1 DNAH2 ABCF2 OSGEP CPT1A URGCP SEC23IP ANKRD17 ARHGEF2 DNAJC3 STAG2

8.04e-079422222131073040
Pubmed

SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.

SYNE2 SYNE1 SUN1

1.02e-064222316648470
Pubmed

Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.

SYNE2 SYNE1 SUN1

1.02e-064222328716842
Pubmed

LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.

SYNE2 SYNE1 SUN1

1.02e-064222323071752
Pubmed

Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.

SYNE2 SYNE1 SUN1

1.02e-064222320108321
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SETX SAMD9 NOL6 SREBF2 ZZEF1 GNPAT DHX16 OGT DICER1 URGCP AP5B1 AACS ANKRD17 TNFAIP2 ARHGEF2 AGRN RUBCN

1.13e-066502221738777146
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH5 DNAH3 DNAH2 DNAH17

1.54e-061422249373155
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

SPTBN1 NCBP1 FAM98B ELAC2 DAP3 FARSA TNPO1 COPA ANXA4 SUN1 ABCF2 LARS2 CBS MYL12A ZC3HAV1L TOP1

2.13e-066072221639147351
Pubmed

LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.

SYNE2 SYNE1 SUN1

2.54e-065222322632968
Pubmed

Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.

SYNE2 SYNE1 SUN1

2.54e-065222318396275
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

CPNE8 SETX SPTBN1 NOL6 NCBP1 FAM98B CWC25 TBC1D8B FARSA NKTR METTL17 DHX16 EP400 COPA FXR2 DDX52 ANXA4 DICER1 TMED4 MYL12A PAXBP1 ANKRD17 ARHGEF2 ENO1 TOP1

2.67e-0613712222536244648
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

OMA1 MYCBP2 ZZEF1 ELAC2 DAP3 MIA2 SYNE2 SCFD1 RAB29 METTL17 NDUFAF5 RGPD8 COPA FXR2 SYNE1 SUN1 LARS2 MIGA2 GSTK1 SEC23IP OGDHL PRKCH ARHGEF2 GEN1 TOP1 CYB5A

3.95e-0614962222632877691
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

DCAF1 RNGTT MYCBP2 CWC25 TUFT1 NRXN1 OSBPL1A NKTR TNPO1 CUL4A AMPD2 CNOT11 OGT ANK3 NEK7 OSGEP CREBBP CBS DICER1 URGCP TMED4 EFHC2 SEC23IP MAP3K2

4.56e-0613212222427173435
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

SPTBN1 NCBP1 FAM98B ELAC2 DAP3 FARSA MIA2 SYNE2 TRMT1L CUL4A AMPD2 CNOT11 OGT COPA FXR2 ABCF2 CPT1A CBS MYL12A PAXBP1 ZC3HAV1L ARHGEF2 ENO1 TOP1 STAG2

4.63e-0614152222528515276
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYCBP2 SPTBN1 NOL6 NCBP1 PGAM1 SYNE2 DHX16 TNPO1 COPA FXR2 DDX52 NSD1 DICER1 ANKRD17 TOP1 STAG2

5.37e-066532221622586326
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH5 DNAH3 DNAH2

8.81e-06722239256245
Pubmed

The HIV-1 protein Vpr targets the endoribonuclease Dicer for proteasomal degradation to boost macrophage infection.

DCAF1 CUL4A DICER1

8.81e-067222323849790
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH5 DNAH2 DNAH17

8.81e-067222331178125
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MYCBP2 ARHGEF11 ZZEF1 ELAC2 RYR1 PCNX2 SH3TC1 TPST2 EP400 RNPEPL1 NSD1 LARS2 MROH1 MEGF8 MTMR14 OGDHL LRRC14 TNFAIP2 LTK ARHGEF2 AGRN

9.52e-0611052222135748872
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NOL6 RYR1 RYR2 FER1L6 DAP3 SYNE2 FXR2 DNAH2 CREBBP MEGF8 IL22 SEC23IP ANKRD17 ARHGEF2 STAG2

1.72e-056382221531182584
Pubmed

Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.

SYNE2 SYNE1 SUN1

2.98e-0510222328533284
Pubmed

The functions of the HIV1 protein Vpr and its action through the DCAF1.DDB1.Cullin4 ubiquitin ligase.

DCAF1 CUL4A CREBBP

2.98e-0510222320347598
Pubmed

Nuclear membrane proteins with potential disease links found by subtractive proteomics.

SYNE2 SYNE1 SUN1

2.98e-0510222312958361
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

RNGTT MYCBP2 NOL6 NCBP1 FARSA TRMT1L METTL17 COPA FXR2 DDX52 ABCF2 URGCP IGHMBP2 OGDHL ARHGEF2 TOP1

3.38e-057592221635915203
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

CPNE8 MYCBP2 NOL6 NCBP1 MYO5C SYNE2 DHX16 TNPO1 EP400 COPA DDX52 SYNE1 SUN1 ABCF2 DICER1 ARHGEF2 ENO1 TOP1 STAG2

3.55e-0510242221924711643
Pubmed

Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study.

GNPDA2 GNPDA1

4.06e-052222212965206
Pubmed

[Determination of the binding site of testis-specific nucleoporin BS-63 to transportin (karopherin beta 2) and the proof of their combination in vitro].

RGPD5 TNPO1

4.06e-052222212905863
Pubmed

Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGF-beta signaling.

GRAPL GRAP

4.06e-052222219836472
Pubmed

Cloning and functional characterization of GNPI2, a novel human homolog of glucosamine-6-phosphate isomerase/oscillin.

GNPDA2 GNPDA1

4.06e-052222212616532
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE2 SYNE1

4.06e-052222211792814
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE2 SYNE1

4.06e-052222224931616
Pubmed

Acetoacetyl-CoA synthetase, a ketone body-utilizing enzyme, is controlled by SREBP-2 and affects serum cholesterol levels.

SREBF2 AACS

4.06e-052222222985732
Pubmed

Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise.

DICER1 PRKAA2

4.06e-052222232900951
Pubmed

Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction.

GRAPL GRAP

4.06e-052222211971956
Pubmed

Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.

RYR1 RYR2

4.06e-052222217259277
Pubmed

Ryanodine receptor oligomeric interaction: identification of a putative binding region.

RYR1 RYR2

4.06e-052222214722100
Pubmed

Liver X receptor α and farnesoid X receptor are major transcriptional regulators of OATP1B1.

NR1H4 SLCO1B1

4.06e-052222220827719
Pubmed

Structural and functional interactions within ryanodine receptor.

RYR1 RYR2

4.06e-052222226009179
Pubmed

Transcriptional Control of Trpm6 by the Nuclear Receptor FXR.

TRPM6 NR1H4

4.06e-052222235216094
Pubmed

Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.

RYR1 RYR2

4.06e-052222232899693
Pubmed

Converging TLR9 and PI3Kgamma signaling induces sterile inflammation and organ damage.

PIK3CG TLR9

4.06e-052222231836766
Pubmed

Arg and DAP3 expression was correlated with human thymoma stage.

ABL2 DAP3

4.06e-052222215679048
Pubmed

Insights into Vitamin D metabolism using cyp24 over-expression and knockout systems in conjunction with liquid chromatography/mass spectrometry (LC/MS).

CYP24A1 GC

4.06e-052222215225763
Pubmed

Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.

RYR1 RYR2

4.06e-052222215033925
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE2 SYNE1

4.06e-052222222768332
Pubmed

Detection of Grb-2-related adaptor protein gene (GRAP) and peptide molecule in salivary glands of MRL/lpr mice and patients with Sjögren's syndrome.

GRAPL GRAP

4.06e-052222215174222
Pubmed

Serum vitamin D metabolites in colorectal cancer patients receiving cholecalciferol supplementation: correlation with polymorphisms in the vitamin D genes.

CYP24A1 GC

4.06e-052222223456391
Pubmed

GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo.

GRK2 GLP1R

4.06e-052222233658023
Pubmed

Ankyrin-G and beta2-spectrin collaborate in biogenesis of lateral membrane of human bronchial epithelial cells.

SPTBN1 ANK3

4.06e-052222217074766
Pubmed

CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5.

LAMA3 CREBBP

4.06e-052222216219677
Pubmed

The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation.

NR1H4 TLR9

4.06e-052222223372731
Pubmed

Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.

SYNE2 SYNE1

4.06e-052222217267447
Pubmed

Grb2-related adaptor protein GRAP is a novel regulator of liver fibrosis.

GRAPL GRAP

4.06e-052222237343720
Pubmed

Nesprins: tissue-specific expression of epsilon and other short isoforms.

SYNE2 SYNE1

4.06e-052222224718612
Pubmed

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

SYNE2 SYNE1

4.06e-052222224586179
Pubmed

Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception.

PIK3CG PIP5K1B

4.06e-052222223236288
Pubmed

SHOC1 is a ERCC4-(HhH)2-like protein, integral to the formation of crossover recombination intermediates during mammalian meiosis.

SHOC1 TEX11

4.06e-052222229742103
Pubmed

Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.

RYR1 RYR2

4.06e-052222230542613
Pubmed

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

SYNE2 SYNE1

4.06e-052222217761684
Pubmed

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

SYNE2 SYNE1

4.06e-052222231578382
Pubmed

Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.

RYR1 RYR2

4.06e-052222215280431
Pubmed

Expression of the ryanodine receptor isoforms in immune cells.

RYR1 RYR2

4.06e-052222211673493
Pubmed

B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.

RYR1 RYR2

4.06e-052222211673462
Pubmed

Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.

RYR1 RYR2

4.06e-052222225370123
Pubmed

Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.

RYR1 RYR2

4.06e-052222218618700
Pubmed

A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.

SYNE2 SYNE1 SUN1

4.08e-0511222322826121
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

NOL6 NCBP1 FAM98B DAP3 FARSA NKTR SCFD1 TRMT1L DHX16 CUL4A OGT EP400 COPA FXR2 DDX52 ABCF2 PAXBP1 GSTK1 ARHGEF2 ENO1 AGRN TOP1

4.19e-0513182222230463901
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DCAF1 CPNE8 MYO5C PXDN COPA DICER1 ANKRD17 ARHGEF2

5.03e-05202222833005030
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

ABL2 ARHGEF11 RYR1 MIA2 KCNN1 NR1H4 TNPO1 CACNA1F TLR9 RPUSD2

5.58e-053292221017474147
Pubmed

Defining the membrane proteome of NK cells.

MYCBP2 MARCHF6 PGAM1 FARSA GRK2 MIA2 PIK3CG GNPAT COPA FXR2 DDX52 ABCF2 CPT1A GSTK1 IGHMBP2 ANKRD17 ENO1 DNAJC3 STAG2 CYB5A

6.70e-0511682222019946888
Pubmed

KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.

SYNE2 SYNE1 SUN1

7.00e-0513222321177258
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SETX MYCBP2 SPTBN1 NCBP1 LRCH1 DAP3 FARSA NRXN1 DHX16 TNPO1 OGT EP400 COPA SYNE1 MYL12A PAXBP1 ARHGEF2 AGRN TOP1

7.37e-0510822221938697112
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

MYCBP2 DIS3L SPTBN1 NCBP1 MIA2 NECAB1 OSBPL1A KCNN1 OGT ANK3 COPA SYNE1 ITSN1 CFAP298 CREBBP CBS SLC4A3 TMED4 SEC23IP GEN1 TOP1

8.47e-0512852222135914814
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

SETX RNGTT NCBP1 ZZEF1 RYR1 IGSF10 DENND4B CACNA1F UBQLNL DNAH3 FXR2 ITSN1 DNAH2 BRME1 MYL12A

8.66e-057362221529676528
Pubmed

SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.

SYNE2 SYNE1 SUN1

8.87e-0514222319874786
Pubmed

MED12 regulates a transcriptional network of calcium-handling genes in the heart.

RYR1 RYR2 KCNN1

8.87e-0514222328724790
Pubmed

Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation.

SETX SPTBN1 NKTR MYL12A

9.05e-0537222423180766
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

ABRA MYCBP2 SPTBN1 MYOZ2 RYR1 SYNE2 SYNE1 ABCF2 OSGEP MTMR14 ENO1 STAG2

9.40e-054972221223414517
Pubmed

Mitochondrial Raf1 Regulates Glutamine Catabolism.

SAMD9 MYCBP2 NAA35 ANK3 ANXA4 CPT1A DICER1 GSTK1 TNS1

1.07e-04288222938496616
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DCAF1 DIS3L PLCXD1 ZZEF1 DAP3 NAA35 SH3TC1 ANKRD2 ABHD8 CUL4A OGT EP400 FXR2 DDX52 CREBBP DICER1 ANKRD17 LTK TOP1

1.10e-0411162221931753913
Pubmed

A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice.

PGAM1 CPT1A PRKAA2 ENO1

1.12e-0439222433059001
Pubmed

Integrative predictive model of coronary artery calcification in atherosclerosis.

SREBF2 ADORA2B NR1H4 AMPD2 ATG9B TLR9 CBS PRKAA2

1.21e-04229222819948975
Pubmed

DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4).

SETX IGHMBP2

1.21e-043222215106121
Pubmed

Ankyrin-G is a molecular partner of E-cadherin in epithelial cells and early embryos.

SPTBN1 ANK3

1.21e-043222217620337
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR2

1.21e-043222218403125
Pubmed

Synthetic interleukin 22 (IL-22) signaling reveals biological activity of homodimeric IL-10 receptor 2 and functional cross-talk with the IL-6 receptor gp130.

IL10RB IL22

1.21e-043222232611765
Pubmed

Multifaceted activity of HIV Vpr/Vpx proteins: the current view of their virological functions.

DCAF1 CUL4A

1.21e-043222220069611
Pubmed

Temporal associations between interleukin 22 and the extracellular domains of IL-22R and IL-10R2.

IL10RB IL22

1.21e-043222215120653
Pubmed

Expression feature of CD3, FcεRIγ, and Zap-70 in patients with chronic lymphocytic leukemia.

ZAP70 PRKCH

1.21e-043222222664044
Pubmed

Upregulation of α enolase (ENO1) crotonylation in colorectal cancer and its promoting effect on cancer cell metastasis.

CREBBP ENO1

1.21e-043222234547627
Pubmed

Jak-STAT3 pathway triggers DICER1 for proteasomal degradation by ubiquitin ligase complex of CUL4A(DCAF1) to promote colon cancer development.

CUL4A DICER1

1.21e-043222226965998
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR1 RYR2

1.21e-04322227876312
Pubmed

Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells.

RYR1 RYR2

1.21e-043222224123915
GeneFamilyEF-hand domain containing

CAPN12 ZZEF1 TBC1D8B RYR2 NECAB1 CLXN S100A7L2 ITSN1 DUOX2 PLCD4 MYL12A EFHC2

3.39e-0721915212863
GeneFamilyDyneins, axonemal

DNAH5 DNAH3 DNAH2 DNAH17

1.05e-05171524536
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR2

2.09e-0431522287
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE2 SYNE1

4.17e-04415221252
GeneFamilySH2 domain containing

ABL2 GRAPL ZAP70 TNS1 GRAP

1.63e-031011525741
CoexpressionGSE36009_WT_VS_NLRP10_KO_DC_DN

TBC1D8B ADORA2B PIK3CG OGT MTMR14 AP5B1 SEC23IP TNFAIP2 ARHGEF2 TOP1

7.30e-0619921910M8777
CoexpressionGSE24726_WT_VS_E2_2_KO_PDC_DN

DCAF1 ABCA3 NCBP1 FAM98B TPST2 SUN1 ABCF2 AACS DNAJC3 CYB5A

7.62e-0620021910M8061
ToppCellPND01-03-samps-Epithelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TRPM6 ABCA3 TUFT1 MYO5C PIP5K1B TSPAN11 ANK3 ANXA4 LAMA3

3.70e-0718522092b854df79cfe2cb4d2f9c2938a066e0aa3649325
ToppCell15-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

CATIP CFAP251 NME9 DNAH5 DNAH3 ATG9B CLXN DNAH2 CFAP210

3.70e-0718522090998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCA3 PLCXD1 ADGRV1 NECAB1 PIP5K1B ANK3 HIF3A ARHGEF2 CYB5A

4.05e-0718722095df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TRPM6 ABCA3 TUFT1 MYO5C PIP5K1B TSPAN11 ANK3 ANXA4 LAMA3

4.05e-07187220923fe3cdd6cc9b067086a8392d104186d300298ea
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

ABCA3 ADGRV1 MYO5C KCNQ3 PIP5K1B DNAH5 ANK3 LAMA3 CYB5A

4.24e-071882209c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCBP1 SYNE2 NKTR RGPD5 OGT SYNE1 ZAP70 MYL12A PRKCH

4.43e-0718922090e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRTM3 ADGRV1 MYO5C NECAB1 FGFR3 ANK3 LAMA3 HIF3A ARHGEF2

4.63e-0719022098aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA3 ADGRV1 MYO5C NECAB1 ANKDD1B KCNQ3 PIP5K1B DNAH5 ANK3

5.06e-071922209cc9911e182a289779a2612bc213daae5607689e7
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

ABCA3 ADGRV1 MYO5C KCNQ3 PIP5K1B DNAH5 ANK3 LAMA3 CYB5A

5.06e-071922209efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP251 SPTBN1 SYNE2 DNAH5 DNAH3 CLXN ANK3 SYNE1 CFAP210

5.76e-071952209fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP251 SPTBN1 SYNE2 DNAH5 DNAH3 CLXN ANK3 SYNE1 CFAP210

5.76e-071952209eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ABCA3 ADGRV1 LRCH1 MYO5C SYNE2 DNAH5 CACNA1F LAMA3 OGDHL

6.27e-071972209b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

AADAC ABCA3 PLCXD1 ADGRV1 MYO5C ANK3 LAMA3 SYTL5 OGDHL

6.27e-07197220944a59dfb889577b3160a5b13ada1276771a00241
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ABCA3 ADGRV1 MYO5C SYNE2 CACNA1F ANK3 LAMA3 SYTL5 OGDHL

6.27e-0719722093d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NME9 DNAH5 DNAH3 CLXN DNAH2 DUOX2 CFAP210 SLC9A4

1.07e-0615522085f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT2_Precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

TRPM6 ABCA3 GC MYO5C PIP5K1B DNAH5 ANK3 LAMA3

1.07e-0615522089cad73d0b8ead289e1073d1a2e00bbeb1228308c
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NME9 DNAH5 DNAH3 CLXN DNAH2 DUOX2 CFAP210 SLC9A4

1.07e-0615522080944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell15-Airway-Epithelial-Multiciliated_precursor|Airway / Age, Tissue, Lineage and Cell class

CFAP251 MYO5C DNAH5 ATG9B CLXN CFAP210 EFHC2 DNAH17

3.01e-061782208d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGRV1 TUFT1 FER1L6 MYO5C NKTR ANK3 SUN1 PRKAA2

3.14e-0617922086e965e424eebef50f0202cff75f458be395cfca1
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

ABCA3 ADGRV1 NECAB1 KCNQ3 PIP5K1B ANK3 SYNE1 CYB5A

3.27e-061802208198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

ABRA MYOZ2 LRRTM3 RYR2 ANKRD2 ANK3 MYL12A PRKAA2

3.55e-061822208287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA3 ADGRV1 NECAB1 KCNQ3 PIP5K1B ANK3 LAMA3 CYB5A

3.69e-0618322086847c1252d6bb105524f812658112517fd351eab
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CATIP CFAP251 DNAH5 DNAH3 CLXN DNAH2 CFAP210 EFHC2

4.00e-0618522083e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP251 NME9 ANKDD1B DNAH5 DNAH3 DNAH2 CFAP210 EFHC2

4.00e-0618522085e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CATIP CFAP251 DNAH5 DNAH3 CLXN DNAH2 CFAP210 EFHC2

4.33e-0618722089e10ed56090d82589bc457788282f664b70ace4b
ToppCelldroplet-Thymus-nan-18m-Myeloid-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AADAC MYO5C FGFR3 NR1H4 ANK3 CBS PRKAA2 AGRN

4.33e-061872208ed69e7cbd6fb59363b0e26f24887fc49405397ce
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

CYP24A1 ADGRV1 FER1L6 MYO5C FGFR3 DNAH5 ANK3 CYB5A

4.69e-06189220884d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 ABCA3 TUFT1 MYO5C MIA2 TSPAN11 ANK3 TEX11

5.06e-061912208c06bbad24e4897b2c3b5015e4de02411ebf75367
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA3 ADGRV1 MYO5C NECAB1 PIP5K1B ANK3 LAMA3 CYB5A

5.06e-061912208e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellfacs-Lung-nan-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 ABCA3 TUFT1 MYO5C MIA2 TSPAN11 ANK3 TEX11

5.06e-0619122085f43f98cfe7a08d61ed55f34808fabfe47f1ac2e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCA3 ADGRV1 PIP5K1B ANK3 LAMA3 HIF3A ARHGEF2 CYB5A

5.26e-06192220829f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

ABCA3 ADGRV1 MYO5C NECAB1 KCNQ3 PIP5K1B DNAH5 ANK3

5.26e-06192220806013a07e3a873b1d1c0451643c528593ac32a9c
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 ABCA3 TUFT1 MYO5C ADORA2B PIP5K1B TSPAN11 ANK3

5.26e-0619222084a46f7980ec145be5b4bf8b98265e3e0f2ea4c63
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

ABCA3 ADGRV1 MYO5C NECAB1 KCNQ3 PIP5K1B ANK3 CYB5A

5.26e-06192220858c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP251 DNAH5 DNAH3 CLXN SYNE1 DNAH2 CFAP210 IL7

5.47e-061932208ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE2 NKTR OGT ANK3 SYNE1 TEX11 ZAP70 SLC9A4

5.47e-0619322089337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA3 ADGRV1 MYO5C KCNQ3 PIP5K1B ANK3 SYNE1 LAMA3

5.68e-06194220853f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP251 NME9 DNAH5 DNAH3 CLXN DNAH2 CFAP210 EFHC2

5.68e-0619422081ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA3 PLCXD1 ADGRV1 NECAB1 PIP5K1B ANK3 SYNE1 LAMA3

5.68e-06194220897534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 SHOC1 DNAH5 DNAH3 CLXN SYNE1 DNAH2 CFAP210

5.68e-0619422084a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

SPTBN1 SYNE2 NKTR OGT ANK3 ZAP70 LRRN3 PRKCH

5.90e-0619522084bdedd924564a260841a9153604026b57487c83d
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP251 DNAH5 DNAH3 CLXN SYNE1 DNAH2 CFAP210 EFHC2

5.90e-0619522083486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA3 ADGRV1 MYO5C PIP5K1B DNAH5 ANK3 SYNE1 LAMA3

5.90e-0619522089406866f99555198a9be311fbd65751b70f35446
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP251 SPTBN1 SYNE2 DNAH5 DNAH3 ANK3 SYNE1 CFAP210

6.12e-0619622086d02d494196e3f857d53eea46d9419690d43beca
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP251 SPTBN1 SYNE2 DNAH5 DNAH3 ANK3 SYNE1 CFAP210

6.12e-061962208af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

SPTBN1 PXDN SYNE2 GRAPL SYNE1 HIF3A PRKCH LTK

6.12e-06196220849cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

SPTBN1 PXDN SYNE2 GRAPL SYNE1 HIF3A PRKCH LTK

6.12e-0619622084ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE2 NKTR OGT ANK3 SYNE1 TEX11 ZAP70 SLC9A4

6.35e-06197220857ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE2 NKTR RGPD5 OGT ANK3 SYNE1 ZAP70 PRKCH

6.35e-061972208e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA3 ADGRV1 MYO5C NECAB1 KCNQ3 PIP5K1B LAMA3 CYB5A

6.84e-061992208725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA3 SREBF2 ADGRV1 MYO5C PIP5K1B ANK3 LAMA3 CYB5A

6.84e-0619922085cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

SETX SYNE2 OSBPL1A DNAH5 ITSN1 MYL12A DNAJC3 STAG2

6.84e-061992208fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE2 NKTR RGPD5 OGT ANK3 SYNE1 ZAP70 PRKCH

6.84e-061992208f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA3 ADGRV1 MYO5C NECAB1 KCNQ3 PIP5K1B ANK3 LAMA3

6.84e-0619922088587bd98de7767a575088afbea07a1feb4516b9b
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CATIP CFAP251 DNAH5 DNAH3 CLXN DNAH2 CFAP210 EFHC2

7.10e-0620022085abd6d81e1cc354484ae693fcd708d78926e75b5
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CATIP CFAP251 DNAH5 DNAH3 CLXN DNAH2 CFAP210 EFHC2

7.10e-0620022089c9d2b0276c7b0709c2eeeb0673a2f58106fb14e
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-AT1_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TBC1D8B ELAC2 FGFR3 ABCF2 BBS10 SLC35F4 PRKAA2

7.92e-061452207186b8bd8ac2d5c66cc29fdc2dd6751eddce3e8b8
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CATIP NME9 DNAH5 DNAH3 CLXN DNAH2 CFAP210

1.17e-0515422074e3bc24043144143842627cacf6f90dda2228910
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CATIP NME9 DNAH5 DNAH3 CLXN DNAH2 CFAP210

1.17e-0515422077556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRPM6 CYP24A1 NRXN1 ANK3 WDR87 PSKH2 CYB5A

1.33e-0515722076ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABRA SPTBN1 BCHE GRAPL NIPAL4 PRKCH GRAP

1.63e-0516222075428c9fdb816f564395ebb4520448e5f3a42b025
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NME9 DNAH5 DNAH3 CLXN DNAH2 DUOX2 SLC9A4

1.76e-051642207e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCellmild_COVID-19_(asymptomatic)-CD4+_T_naive|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

SERPINE3 ABCD2 FBLN7 ANK3 HIF3A FREM3 LRRN3

1.98e-05167220778d264af390bd89942ffbb2991dc94f50756d4c9
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SAMD9 NME9 SYNE2 TPST2 SYNE1 LRRN3 PRKCH

2.06e-051682207b94b1f37c92e019d01ecfa3b7cc6797b6e4a56ff
ToppCellControl|World / group, cell type (main and fine annotations)

ABCA3 ADGRV1 MYO5C PIP5K1B ANK3 SYNE1 LAMA3

2.06e-051682207a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FER1L6 SH3TC1 SHOC1 TMEM117 ANXA4 LAMA3 PSKH2

2.14e-051692207a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

AADAC PXDN SHOC1 KCNQ3 LAMA3 SYTL5 AGRN

2.40e-0517222070be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BCHE FER1L6 FIBIN GLP1R LAMA3 IL7

2.67e-0511822063f0a304ef9c9e5ba047fc09f4372590eed624328
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABRA MYOZ2 LRRTM3 RYR2 ANKRD2 MYL12A PRKAA2

2.78e-0517622079df7a124ebafb0087da0cda133a394275d7bed81
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

AADAC PDE1A ADGRV1 FGFR3 ANK3 HIF3A CYB5A

3.09e-051792207815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 ABCA3 ADGRV1 MYO5C SYNE2 ANK3 LAMA3

3.09e-051792207fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

ADGRV1 KCNQ3 DNAH5 TSPAN11 ANK3 TOP1 CYB5A

3.32e-051812207c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

CFAP251 DNAH5 DNAH3 CLXN DNAH2 CFAP210 EFHC2

3.44e-051822207fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellCV-Severe-4|CV / Virus stimulation, Condition and Cluster

PGAM1 PIP5K1B FBLN7 NIPAL4 CBS ZC3HAV1L ENO1

3.44e-051822207c19bbc43d97c426aec37414f46f667a19b62a257
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

ABCA3 SPTBN1 ADGRV1 KCNQ3 ANK3 LAMA3 SLC35F4

3.56e-051832207dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCellPND07-28-samps-Epithelial-Alveolar_epithelial-AT2|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TRPM6 ABCA3 MYO5C ADORA2B PIP5K1B TSPAN11 ANK3

3.56e-0518322070a69e22750dd8b66ab988cf36d0dd2b59e2f7d26
ToppCellPND07-28-samps-Epithelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TRPM6 ABCA3 MYO5C ADORA2B PIP5K1B DNAH5 ANK3

3.56e-051832207a98f1d71d82ed6cca996f74352ab834fb6e95206
ToppCellPND07-28-samps-Epithelial-Alveolar_epithelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TRPM6 ABCA3 MYO5C ADORA2B PIP5K1B TSPAN11 ANK3

3.56e-05183220723e55f88a802a9299d2773f9394970e86e8bbfaa
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

MYOZ2 LRRTM3 RYR2 ANKRD2 ANK3 MYL12A PRKAA2

3.69e-051842207ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

ABCA3 ADGRV1 MYO5C KCNQ3 PIP5K1B ANK3 CYB5A

3.69e-051842207369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

CAPN12 PDE1A ADGRV1 KCNQ3 DNAH5 ANK3 CYB5A

3.82e-051852207673f0c688ae6984bc8027df2da335787924f4137
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA3 ADGRV1 MYO5C PIP5K1B ANK3 LAMA3 PAXBP1

3.82e-0518522070d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

MYOZ2 LRRTM3 RYR2 ANKRD2 ANK3 MYL12A PRKAA2

3.82e-0518522076baccb26f999145e51b91d94315bf8d4655bef31
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

CFAP251 DNAH5 DNAH3 CLXN DNAH2 CFAP210 EFHC2

3.82e-05185220718a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

CFAP251 NME9 DNAH3 CLXN DNAH2 CFAP210 EFHC2

3.82e-05185220730f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

AADAC PDE1A ADGRV1 MYO5C DNAH5 ANK3 CYB5A

3.95e-0518622072ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CATIP CFAP251 NME9 DNAH3 CLXN DNAH2 CFAP210

3.95e-05186220785787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP251 NME9 DNAH5 DNAH3 CLXN DNAH2 CFAP210

3.95e-05186220776033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCHE MYO5C FGFR3 LARS2 CBS TNS1 AGRN

4.09e-0518722079aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SAMD9 GLP1R SYNE2 TPST2 SYNE1 ZAP70 PRKCH

4.09e-0518722070bca79cea4886b66350c56c61859bd71e1e7a85c
ToppCellCiliated_cells-B-HP_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP251 NME9 DNAH3 CLXN DNAH2 CFAP210 EFHC2

4.09e-051872207bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 ABCA3 MYO5C ADORA2B PIP5K1B TSPAN11 ANK3

4.23e-051882207b1049003ca79c340bb8c78da66bdc0956e1aebc2
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 ABCA3 MYO5C ADORA2B PIP5K1B TSPAN11 ANK3

4.23e-0518822073dd571bd8e7358b4346dea71f6bf9602dabf583c
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

CFAP251 DNAH5 DNAH3 CLXN DNAH2 CFAP210 EFHC2

4.23e-051882207606907c865bd2f11bb6474932716550f7723d858
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

ABCA3 ADGRV1 MYO5C PIP5K1B DNAH5 ANK3 LAMA3

4.23e-051882207707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFAP251 DNAH5 DNAH3 CLXN DNAH2 CFAP210 EFHC2

4.37e-051892207a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellAdult|World / Lineage, Cell type, age group and donor

CAPN12 ABCA3 SREBF2 KCNQ3 DNAH5 CPT1A MROH1

4.37e-0518922075cd285bfad973125d46d704fec18b21266a63379
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

CFAP251 DNAH5 DNAH3 CLXN DNAH2 CFAP210 EFHC2

4.37e-05189220727329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCiliated|World / shred by cell class for parenchyma

CATIP CFAP251 DNAH5 CLXN DNAH2 CFAP210 EFHC2

4.37e-051892207711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCD2 ANXA4 CPT1A ATP10A SLC9A4 TNFAIP2 TNS1

4.37e-051892207287e59104687fe1665232c52993889f0f2c97f17
DrugAmrinone [60719-84-8]; Down 200; 21.4uM; PC3; HT_HG-U133A

DCAF1 AADAC RNGTT SPTBN1 PCNX2 SH3TC1 DNAH3 SYNE1 RNPEPL1 CPT1A CEP250 TNS1

4.16e-07193220124488_DN
DrugMidecamycin [35457-80-8]; Down 200; 5uM; PC3; HT_HG-U133A

ABCA3 SPTBN1 TBC1D8B MIA2 MPPE1 OGT ABCF2 CPT1A CEP250 TNS1 AGRN

3.46e-06196220116745_DN
Drugdiacetylene

ABRA ASIC2 SYNE1 CBS

7.87e-06142204CID000009997
Drugmagnesium

TRPM6 SPTBN1 BCHE GC ADGRV1 RYR1 RYR2 MYO5C FARSA GRK2 KCNJ4 FGFR3 DNAH5 CARD14 TNPO1 DNAH3 AMPD2 DDX52 ABCB5 LAMA3 OSGEP DICER1 ZAP70 MYL12A FARS2 DNAH17 PRKCH ENO1 TOP1 CYB5A

1.26e-05132522030CID000000888
Drugoxotremorine-M

PLCXD1 BCHE KCNQ3 TNPO1 SYNE1 PLCD4 TNS1

1.36e-05812207CID000004629
Drugglucosaminitol

GC GNPDA2 GNPDA1 OGT

1.41e-05162204CID000189022
Drugmonomethylarsonic acid

ABRA SETX TYRO3 TNPO1 OTP IGHMBP2

1.65e-05562206CID000008947
Drug5114445; Down 200; 10uM; MCF7; HT_HG-U133A_EA

RNGTT PDPK1 NKTR FGFR3 FXR2 DDX52 ABCF2 DICER1 CEP250 RUBCN

1.94e-0519322010901_DN
Druglindane

RNGTT PLCXD1 RYR1 RYR2 FGFR3 CACNA1F PLCD4 CBS TNFAIP2

1.96e-051542209CID000000727
DrugPyrazinamide [ 98-96-4]; Down 200; 32.4uM; HL60; HT_HG-U133A

MARCHF6 ARHGEF11 GRK2 GLP1R PIP5K1B NKTR CPT1A MEGF8 CEP250 ZMYM6

2.12e-05195220102478_DN
DrugPNU-0251126 [267429-19-6]; Up 200; 10uM; PC3; HT_HG-U133A

ABCA3 RNGTT NR1H4 NDUFAF5 FXR2 ABCF2 CPT1A ATP10A SLC16A4 TNFAIP2

2.31e-05197220107388_UP
DrugPridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; PC3; HT_HG-U133A

SETX RNGTT GRK2 KCNJ4 GLP1R NDUFAF5 RNPEPL1 ABCF2 IGHMBP2 PRKCH

2.31e-05197220105860_UP
DrugFamotidine [76824-35-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A

DCAF1 ABL2 SPTBN1 RYR1 MIA2 ITSN1 SUN1 KCTD17 FARS2 IL22

2.41e-05198220101529_UP
DrugSulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; PC3; HT_HG-U133A

SAMD9 RNGTT SPTBN1 SH3TC1 DNAH3 SYNE1 KCTD17 PRKAA2 OGDHL TNS1

2.41e-05198220103711_DN
DrugChlorpheniramine maleate [113-92-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A

DCAF1 SREBF2 LRCH1 RYR2 PCNX2 ITSN1 SUN1 NSD1 CEP250 HERC4

2.41e-05198220102217_DN
DrugImipramine hydrochloride [113-52-0]; Down 200; 12.6uM; HL60; HT_HG-U133A

RNGTT NCBP1 GRK2 OSBPL1A CPT1A URGCP BBS10 LRRC14 AGRN ZMYM6

2.41e-05198220101849_DN
Drugverapamil

ADCY10 ABRA ABCA3 CYP24A1 RYR1 RYR2 KCNJ4 KCNN1 KCNQ3 ABCD2 CACNA1F ABCB5 ABCF2 SLCO1B1 SEC23IP PRKCH

2.45e-0549022016CID000002520
DrugRepaglinide [135062-02-1]; Down 200; 8.8uM; PC3; HT_HG-U133A

CWC25 PCNX2 TPST2 EP400 COPA FXR2 DDX52 FARS2 LRRC14 DNAJC3

2.63e-05200220105862_DN
Drugdiphenylmethane

CYP24A1 GC NR1H4 SYNE1

2.93e-05192204CID000007580
DrugFA 5

FARSA LARS2 CBS FARS2

3.64e-05202204CID000193730
DrugCHEMBL2115063

ADORA2B GNPDA2 TNPO1 GNPDA1 TNS1

4.02e-05402205CID009876936
Drugcarbachol

ADCY10 PDE1A PLCXD1 BCHE RYR1 RYR2 MYO5C ADORA2B GRK2 PIK3CG KCNJ4 KCNN1 CARD14 CACNA1F LAMA3 PLCD4 MYL12A SEC23IP PRKCH

4.27e-0568822019CID000002551
DiseaseStatin causing adverse effect in therapeutic use

RYR1 SLCO1B1

5.04e-0522102cv:C0570410
DiseaseStatin-induced myopathy

RYR1 SLCO1B1

5.04e-0522102cv:CN181199
Diseasesurvival time, Sepsis

SAMD9 FIBIN SLC35F4

7.46e-05122103EFO_0000714, HP_0100806
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR2

1.51e-0432102DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR2

1.51e-0432102DOID:8545 (implicated_via_orthology)
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE2 SYNE1

3.00e-0442102cv:CN293514
DiseaseGingival bleeding

ASIC2 NRXN1

3.00e-0442102HP_0000225
DiseaseJT interval

LRCH1 NAA35 PXDN KCNJ4 RAB29 CUL4A CREBBP SLC4A3

4.25e-042482108EFO_0007885
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE2 SYNE1

4.97e-0452102C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE2 SYNE1

4.97e-0452102C0410190
Diseaseatopy

ADGRV1 PAK5

4.97e-0452102EFO_0002686
Diseaseinterleukin-10 receptor subunit beta measurement

IL10RB ITSN1

4.97e-0452102EFO_0020489
Diseasealcohol use disorder (implicated_via_orthology)

PDPK1 SREBF2 RYR1 RYR2 GLP1R CREBBP PRKCH

5.17e-041952107DOID:1574 (implicated_via_orthology)
Diseaselevel of Sphingomyelin (d40:2) in blood serum

GC SYNE2 ANKRD17

5.67e-04232103OBA_2045181
DiseaseAdenocarcinoma of lung (disorder)

TRPM6 KCNJ4 FGFR3 PAK5 CREBBP ENO1 PSKH2

7.15e-042062107C0152013
DiseaseEmery-Dreifuss muscular dystrophy

SYNE2 SYNE1

7.42e-0462102cv:C0410189
Diseaseprimary progressive multiple sclerosis (is_marker_for)

BCHE GC

7.42e-0462102DOID:0050784 (is_marker_for)
DiseaseBAG family molecular chaperone regulator 4 measurement

BCHE SLCO1B1

7.42e-0462102EFO_0802303
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE2 SYNE1

7.42e-0462102C0410189
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE2 SYNE1

1.03e-0372102C0751337
Diseaselevel of Sphingomyelin (d38:1) in blood serum

GC SYNE2 ANKRD17

1.25e-03302103OBA_2045180
Diseasevitamin D measurement, vitamin D dietary intake measurement

CYP24A1 GC

1.37e-0382102EFO_0004631, EFO_0008539
DiseaseQT interval

ASIC2 NOL6 LRCH1 PXDN KCNJ4 KCNQ3 CUL4A ITSN1 CREBBP SLC4A3 SLC16A4

1.64e-0353421011EFO_0004682
Diseaseanemia (phenotype), response to ribavirin

CYP24A1 DNAH17

1.76e-0392102EFO_0004272, GO_1901559
Diseaseinterferon alpha/beta receptor 1 measurement

IL10RB ITSN1

1.76e-0392102EFO_0021850
DiseaseMalignant neoplasm of breast

ABCA3 PDPK1 CYP24A1 SREBF2 BCHE DAP3 MIA2 SYNE2 SYNE1 CPT1A SLCO1B1 PRKAA2 ENO1 TNS1 GEN1 TOP1 DOP1A

1.85e-03107421017C0006142
Diseasevisceral heterotaxy (implicated_via_orthology)

OSBPL1A DNAH5 MEGF8

2.31e-03372103DOID:0050545 (implicated_via_orthology)
Diseaseresponse to angiotensin-converting enzyme inhibitor

ASIC2 ELAC2 NRXN1 PIP5K1B

2.36e-03782104EFO_0005325
DiseaseC-reactive protein measurement

CFAP251 ZZEF1 JMY PXDN NR1H4 CUL4A FBLN7 ANK3 DDX52 ANXA4 NEK7 HIF3A SLC9A4 RP1L1 DNAH17 AACS CEACAM20 TOP1

2.58e-03120621018EFO_0004458
Diseasehyperhomocysteinemia (implicated_via_orthology)

BCHE CBS

2.66e-03112102DOID:9279 (implicated_via_orthology)
DiseasePancreatic Ductal Adenocarcinoma

ABCD2 ABCB5

2.66e-03112102C1335302
DiseasePR interval

OMA1 MYCBP2 ASIC2 SPTBN1 MYOZ2 LRCH1 RYR2 SYNE2 ABCB5 SUN1

3.04e-0349521010EFO_0004462
DiseaseDrug toxicity

BCHE GC SLCO1B1 TOP1

3.09e-03842104C0013221
DiseaseAdverse reaction to drug

BCHE GC SLCO1B1 TOP1

3.09e-03842104C0041755
Diseaseplatelet component distribution width

CAPN12 ZZEF1 LRCH1 JMY MIA2 ANKDD1B PIP5K1B CUL4A SYNE1 RNPEPL1 TEX11 KCTD17 OTP

3.10e-0375521013EFO_0007984
DiseaseCarcinoma, Transitional Cell

FGFR3 CREBBP STAG2

3.10e-03412103C0007138
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE2 SYNE1

3.17e-03122102DOID:11726 (implicated_via_orthology)
Diseasearachidonoylcarnitine (C20:4) measurement

CPT1A SLCO1B1

3.17e-03122102EFO_0800544
DiseaseAutism Spectrum Disorders

LRRTM3 RYR2 NRXN1 LRRN3

3.22e-03852104C1510586
Diseasefibroblast growth factor 23 measurement

CYP24A1 PIP5K1B NSD1

3.56e-03432103EFO_0009381
Diseasehereditary spastic paraplegia (implicated_via_orthology)

CAPN12 NIPAL4 SEC23IP

3.56e-03432103DOID:2476 (implicated_via_orthology)
DiseaseAutosomal Dominant Myotubular Myopathy

RYR1 MTMR14

3.73e-03132102C3661489
DiseaseCentronuclear myopathy

RYR1 MTMR14

3.73e-03132102C0175709
DiseaseX-linked centronuclear myopathy

RYR1 MTMR14

3.73e-03132102C0410203
Diseasedihomo-linolenoylcarnitine (C20:3n3 or 6) measurement

CPT1A SLCO1B1

3.73e-03132102EFO_0800547
Diseaseximenoylcarnitine (C26:1) measurement

CPT1A IGHMBP2

3.73e-03132102EFO_0800543
Diseasecerotoylcarnitine (C26) measurement

CPT1A IGHMBP2

3.73e-03132102EFO_0800542
DiseaseMyopathy, Centronuclear, 1

RYR1 MTMR14

3.73e-03132102C4551952
Diseasedevelopmental and epileptic encephalopathy (implicated_via_orthology)

KCNQ3 FARS2

3.73e-03132102DOID:0112202 (implicated_via_orthology)
DiseaseCongenital Structural Myopathy

RYR1 MTMR14

3.73e-03132102C0752282
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

SYNE2 ANKDD1B CPT1A TMED4 CEACAM20

3.77e-031442105EFO_0004611, EFO_0020943
DiseaseMultiple Sclerosis

BCHE GC IL7

4.05e-03452103C0026769
DiseaseMultiple Sclerosis, Acute Fulminating

BCHE GC IL7

4.05e-03452103C0751324
Diseaseobesity (biomarker_via_orthology)

SREBF2 GLP1R NR1H4 CPT1A AACS

4.11e-031472105DOID:9970 (biomarker_via_orthology)
DiseaseMyopathy, Centronuclear, Autosomal Dominant

RYR1 MTMR14

4.34e-03142102C1834558
DiseaseTubular Aggregate Myopathy

RYR1 MTMR14

4.34e-03142102C0410207
DiseaseAdenocarcinoma of large intestine

GRK2 FGFR3 PAK5 PRKCH

4.97e-03962104C1319315
DiseaseDown syndrome (implicated_via_orthology)

CBS DOP1A

4.98e-03152102DOID:14250 (implicated_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of bladder

FGFR3 STAG2

4.98e-03152102C0496930
Diseasegamma-glutamylphenylalanine measurement

LRRTM3 ARHGEF2

4.98e-03152102EFO_0021142
DiseaseBenign neoplasm of bladder

FGFR3 STAG2

4.98e-03152102C0154017
DiseaseCarcinoma in situ of bladder

FGFR3 STAG2

4.98e-03152102C0154091
DiseaseAutosomal Recessive Centronuclear Myopathy

RYR1 MTMR14

4.98e-03152102C3645536
Diseaseblood urea nitrogen measurement

PDE1A CYP24A1 MYOZ2 ADGRV1 PIK3CG PIP5K1B TNPO1 PLCD4 AP5B1

5.31e-034522109EFO_0004741
Diseasediastolic blood pressure, body mass index

GLP1R EFHC2

5.66e-03162102EFO_0004340, EFO_0006336
Diseasefilaggrin gene expression measurement

CARD14 SLC35F4

5.66e-03162102EFO_0020899
Diseasealpha fetoprotein measurement

SETX SLCO1B1 ANKRD17 GEN1

5.74e-031002104EFO_0010583
Diseaseepisodic memory

TRPM6 TNPO1 TPST2

6.08e-03522103EFO_0004333
Diseasesphingomyelin 14:0 measurement

SYNE2 PAK5

6.39e-03172102EFO_0010390
Diseasehyperglycemia (implicated_via_orthology)

GRK2 GLP1R

6.39e-03172102DOID:4195 (implicated_via_orthology)
Diseaseulcerative colitis (is_implicated_in)

CYP24A1 GC

6.39e-03172102DOID:8577 (is_implicated_in)
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

IL10RB TLR9

6.39e-03172102DOID:8677 (biomarker_via_orthology)
DiseaseDiffuse Large B-Cell Lymphoma

PDPK1 PIK3CG CREBBP

7.10e-03552103C0079744

Protein segments in the cluster

PeptideGeneStartEntry
MDVHDLFRRLGAGAK

DDX52

1

Q9Y2R4
SMFDLIGLENKITRH

EP400

1411

Q96L91
ADKAEMRASRILHGL

ABCF2

201

Q9UG63
LGRSIATLMSDKLFH

SLC4A3

571

P48751
FLLLCMLIGKSHTED

BCHE

16

P06276
LEKLDSRDGKFIHRM

CWC25

376

Q9NXE8
HVVKVADFGLSRLMT

ABL2

421

P42684
RLNFKVEEGMHLLIT

ABCD2

496

Q9UBJ2
HAAKSLAMIVGIFAL

ADORA2B

231

P29275
ELLGLHHFMDSFKVV

AADAC

51

P22760
ERVILFLKMASGHAF

AACS

581

Q86V21
GEILTMRLRHLAFKA

ABCB5

761

Q2M3G0
LLDAHMNAKIADFGL

PRKAA2

146

P54646
ELLREKVGLFAEMTH

ARHGEF2

606

Q92974
LSIVFHERMQLSKDG

CEACAM20

106

Q6UY09
EEILMKRNHLGAFLI

GRAPL

71

Q8TC17
EEILMKRNHLGAFLI

GRAP

71

Q13588
LHTFARDLGEKMALE

AGRN

1651

O00468
MEFFLPTIHKRASLG

ADGRV1

1831

Q8WXG9
ELLFEAGEMRKSLHV

ADGRV1

4321

Q8WXG9
SLALRDVGMIFHTIE

ARHGEF11

1416

O15085
EQAYLRHLGMLEELK

CCDC96

281

Q2M329
MDGRDAFLTLARDKH

CREBBP

1661

Q92793
GRHLKEAMTDIITLF

CPT1A

751

P50416
AFTRDGHMADTLLLL

ABCA3

1171

Q99758
NLLARHRISVMGKDF

DOP1A

1421

Q5JWR5
TLVFNKLIMGHLDLA

ADCY10

1301

Q96PN6
AEIDMLDIRAHFKRL

ANXA4

276

P09525
FMLAENISHGLLLRK

AMPD2

701

Q01433
KGHLEMVRFLLEAGA

ANKRD17

411

O75179
NLERLEMLGDSFLKH

DICER1

1311

Q9UPY3
LLKSLGIHDLMHFDF

DHX16

766

O60231
EDALHGALKMLRQLF

BBS10

411

Q8TAM1
KMDFTAARLQRGHLL

DNAJC3

101

Q13217
LLHTLGFDSVRKRMS

ATP10A

736

O60312
LLAFLKLIDEGSHMV

ABHD8

386

Q96I13
KLSFILDLMNGGDLH

GRK2

266

P25098
FLRLLVTKGEHMTEE

CFAP251

1071

Q8TBY9
FSMLEFLHRVGHDLK

ASIC2

151

Q16515
GFIDKEDLHDMLASL

MYL12A

46

P19105
HREGMLFISKLDGRL

NSD1

2186

Q96L73
MGSRDHLFKVLVVGD

RAB29

1

O14966
GHMLLSLSRGKQDFL

RGPD5

356

Q99666
GHMLLSLSRGKQDFL

RGPD8

356

O14715
IALLKGSAVEAMFLR

NR1H4

331

Q96RI1
VGIADALIHMTLAFR

OR5W2

151

Q8NH69
AGIIRMLEFGSHLDL

KCNJ4

411

P48050
LHKVSSVLRGFLDLM

PAK5

666

Q9P286
YAIIGLELFLGRMHK

CACNA1F

251

O60840
FAEGIRHMKSRLAAL

FBLN7

51

Q53RD9
LGHLLRILFKNDDFM

DCAF1

71

Q9Y4B6
FIDKLLILEAGHRMS

PSKH2

296

Q96QS6
RASEHMELALGVDLK

MAGEB18

151

Q96M61
ADADIQLKGHMARFL

LAMA3

1016

Q16787
MDEVLASLKRGSFHL

JMY

891

Q8N9B5
LAESDEGKLHVLRVM

NCBP1

576

Q09161
KDLRMHLSNTLLDGE

RNGTT

331

O60942
ASLLGDMHFRSLRTK

FXR2

191

P51116
AREVMILITGAHKAF

GNPDA1

196

P46926
FSMKGLHLDATLDAV

MSS51

191

Q4VC12
GHMLVDRLSKGEEIF

MTMR14

376

Q8NCE2
MDEHARGTLRFIKLF

GLP1R

371

P43220
LGRVMLLHSKIFTDA

KCNN1

241

Q92952
SAGHLDMLSRIKYLQ

KCNQ3

551

O43525
ALGLHVAEMSEKELF

DUOX2

741

Q9NRD8
LDFLMEALIISKFRH

LTK

556

P29376
REPVLKAMFLADTHL

MPPE1

66

Q53F39
KAMFLADTHLLGEFL

MPPE1

71

Q53F39
LPHSSGRDALKMFLR

EFHC2

266

Q5JST6
FMVSILFSKLGDLLH

PCNX2

1271

A6NKB5
MAFGSLLKEGIHVRL

OGDHL

646

Q9ULD0
LLMGFSDERKLQILH

OR14J1

11

Q9UGF5
GIDRAKTMSLILHAA

PDE1A

351

P54750
LELADAGDLSRMIKH

NEK7

111

Q8TDX7
SHRGEKLLLFMGIID

PIP5K1B

336

O14986
VLNHVLRDIELFMGK

EPS8L3

241

Q8TE67
SGVDMNAARLLFHKL

HERC4

456

Q5GLZ8
MDALKDLLRHTGRLS

PRAMEF18

391

Q5VWM3
AKLRPSADELLRHMF

MAP3K2

601

Q9Y2U5
MLLDSRADDGFHLLL

NOL6

446

Q9H6R4
DAREMSKTFIIGELH

CYB5A

71

P00167
IEASSGKMLLHLFSD

MEGF8

111

Q7Z7M0
EMRLKVSLHEDLGAA

LRCH1

591

Q9Y2L9
RMLGLDGSLVFLEHV

MARCHF6

276

O60337
KRRLLMVPDGFISHF

MIGA2

481

Q7L4E1
MLTERGHKLSVLAVD

MMAA

166

Q8IVH4
LTLLHAMLALKAAFG

AP5B1

321

Q2VPB7
IKVDFFAIEMLDGHL

NRXN1

536

Q9ULB1
VKLLASVRALDHAMS

PAXBP1

886

Q9Y5B6
EKMEFRTASIRLFGH

MROH1

1461

Q8NDA8
HRAAFTGRKELVMLL

OSBPL1A

86

Q9BXW6
GILSFIEDVAHRMLA

OSGEP

206

Q9NPF4
FLRHGKLVLDKDMAE

KCTD17

91

Q8N5Z5
RIAHMLEGSEKNLHF

PLCXD1

106

Q9NUJ7
MSILKIHAREIFDSR

ENO1

1

P06733
HRASLEGHMEILEKL

ANKRD2

186

Q9GZV1
MVLLHVKRGDESQFL

CFAP298

1

P57076
SMGLFSALRHALAKE

CAPN12

221

Q6ZSI9
DFSGLTKLELLMLHS

IGSF10

76

Q6WRI0
LIMGTHRDLEAFKRL

BRME1

621

Q0VDD7
SAMRAGHLLDLLKTR

CARD14

66

Q9BXL6
ILDEMSHKLRLGAIR

GNPAT

106

O15228
IFRMKLGSFESVHLG

CYP24A1

96

Q07973
MAEGFLEARLLARKF

DNAH17

1986

Q9UFH2
SLEDLVSLFMIHKDG

DNAH3

456

Q8TD57
ILAGSFETAMRLLHD

COPA

931

P53621
SDLVSDILIHGMKAR

DIS3L

271

Q8TF46
RTLDKIMILFRFIHG

CUL4A

431

Q13619
DGKLTAEEFILAMHL

ITSN1

271

Q15811
MLFGSDRMELLAHLL

GSTK1

196

Q9Y2Q3
DLMELKAEHVRLSGS

CEP250

201

Q9BV73
LGRLSHILEMDHFAL

CBS

496

P35520
LFVHASSRGFLDKML

CATIP

86

Q7Z7H3
HFGSMRGKERELIVL

ANK3

1066

Q12955
ITMAHLLAAREDLSK

FAM98B

266

Q52LJ0
DGKTELSLMRFSLAH

ATG9B

701

Q674R7
EVLADSLHMRFLAPK

IL10RB

121

Q08334
FLKMNSTGDFDLHLL

IL7

91

P13232
AREVMILITGAHKAF

GNPDA2

196

Q8TDQ7
REILFLTMAALGKDH

DENND4B

1431

O75064
LVLLTHYDMIERKLG

GEN1

376

Q17RS7
MKIADFGLARDVHNL

FGFR3

631

P22607
DFLGMLVHTRSLLKE

FIBIN

161

Q8TAL6
EMAAGRLLELHTYLK

DNAH2

1041

Q9P225
IDASMFARKHESPLL

RUBCN

186

Q92622
LSLLGDITIDHHKIM

S100A7L2

76

Q5SY68
AAHLLDIAMGVKTLR

RYR1

4811

P21817
AHLLDIAMGFKTLRT

RYR2

4741

Q92736
AGHSLLMDARDLVLK

METTL17

301

Q9H7H0
HILSMARLAKDVLAE

CPNE8

516

Q86YQ8
MAAYKLVLIRHGESA

PGAM1

1

P18669
FLDHIRKVMLVIDAA

NGB

61

Q9NPG2
MAKVLLEFEVLFHRA

DNAH5

666

Q8TE73
KRMLSFQGLAELAHR

OGT

16

O15294
AKAELATFLRGVLLM

OR52N5

151

Q8NH56
MLSHADLLDARLGMK

OTP

1

Q5XKR4
MAKFGVHRILLLAIS

MIA2

1

Q96PC5
LFAHEFKVLEGMSLV

FREM3

1196

P0C091
MLLFNDLVLHGDVKE

FER1L6

876

Q2WGJ9
HRLDRLTSGVLMFAK

RPUSD2

271

Q8IZ73
ELKRQSSLGMFHLLV

DAP3

246

P51398
SFLLDHEKEMILGVL

SYTL5

11

Q8TDW5
AFRLDALHRQMKLLG

RNPEPL1

401

Q9HAU8
LKRMLFESLHHGLDD

TRMT1L

541

Q7Z2T5
GVMALVFAIKAEERH

TMEM265

46

A0A087WTH1
DSGKLRHVLSMDGFL

PLCD4

256

Q9BRC7
HLMGVLREFFTKLGI

FARSA

386

Q9Y285
GLESHMILTETLFRK

SYNE1

6636

Q8NF91
DFGVRLESLKGLIMH

SYNE2

5501

Q8WXH0
LHGHSSLKEALRMAL

LARS2

321

Q15031
FAGMIRLKELHLEHN

LRRTM3

201

Q86VH5
RRGDFSNMLHLKELG

LRRN3

276

Q9H3W5
LKHDRAFLLSMANRG

NKTR

101

P30414
SFLTHEDIMPRGKFL

SAMD9

526

Q5K651
MDGLKDLLRHTGRLS

PRAMEF19

391

Q5SWL8
RDVMSRLDHPFFVKL

PDPK1

131

O15530
LGRGAFLSRHSLDMK

HIF3A

236

Q9Y2N7
EELHIRLMDHLKAGI

SLC9A4

491

Q6AI14
KYSLFILGHLRTLME

SETX

2416

Q7Z333
EREMTFKHAALLHLL

SHOC1

651

Q5VXU9
GLEFAHMALALSITL

SH3TC1

1171

Q8TE82
ADLKEHMVGIIFSRS

MYCBP2

3946

O75592
HLELKESLSRMGSDL

SEC23IP

856

Q9Y6Y8
DVRLIGEKLFHGVSM

IL22

71

Q9GZX6
KALLHRDTMLAAAAV

NDUFAF5

271

Q5TEU4
MDELLLDLFHKLTSG

SLC35F4

1

A4IF30
HAAEKAGMVHLLDFL

OMA1

336

Q96E52
ELKSLALGFHSMVIR

SLCO1B1

566

Q9Y6L6
LLSKHRAFEDEMSGR

SPTBN1

676

Q01082
LMRARKHGLVDFEGE

ABRA

351

Q8N0Z2
FLLAAERGHVEMIEK

ANKDD1B

206

A6NHY2
HSGLLLSRVMKERDA

CFAP210

156

Q0VFZ6
KMDHRSDLVFLADLR

CHST14

181

Q8NCH0
FSKADHFRLGSVLVM

CNOT11

96

Q9UKZ1
HGLSLFLRGSLEEKM

CLXN

91

Q9HAE3
IFKHGDDLRQDMLIL

PIK3CG

831

P48736
VSVEDMAHAARKLGL

URGCP

446

Q8TCY9
VAGLREKIHHLDDML

TUFT1

281

Q9NNX1
SKFLLMVRDGRASVH

TPST2

176

O60704
EEHLKLAGMADGLFL

ZAP70

21

P43403
VFLHLGRTMKEDLEA

TNFAIP2

216

Q03169
DVMLDTFRLLVSVGH

ZNF135

41

P52742
FLHVRKATRAMGLLN

TMEM175

331

Q9BSA9
LLGIRKFMLERNHTS

ZNF826P

26

Q6ZT77
LAFTHKHLADEGMLR

TRPM6

326

Q9BX84
EALVRMGKDATLLIH

ELAC2

671

Q9BQ52
HLVARAKTLGIDIMD

SLC16A4

321

O15374
GELLHDKLFGLFEAM

NAA35

46

Q5VZE5
LSVEMKVRFHLVGED

RP1L1

321

Q8IWN7
SLLLRMEEVGRKLHS

TBC1D8B

1021

Q0IIM8
LKELDMHGIFFRSLD

TLR9

366

Q9NR96
TREAIAMLHKDGIEF

STAG2

966

Q8N3U4
HKAALAGLSLSLMER

IGHMBP2

411

P38935
VAEKLIRLAGFDEHM

TOMT

171

Q8WZ04
CHLMKDLARTLLTVG

SYCP2L

211

Q5T4T6
KVFLHEATVRLMAGA

SREBF2

1031

Q12772
KGDMTHELVRHFLIE

TNS1

1516

Q9HBL0
GTFNHLESMKRLRLD

PXDN

176

Q92626
MKRVLVLLLAVAFGH

GC

1

P02774
SVKELRDMGITLHLL

SCFD1

61

Q8WVM8
IAKLLMDHERESVGF

TEX11

341

Q8IYF3
HLREGMTLLKTEFAL

SERPINE3

21

A8MV23
KMRIEVGLDLLHFAL

NME9

51

Q86XW9
VLVFMGCLLKDHDTL

UBQLNL

71

Q8IYU4
KLEQFLADHLLLMGA

TSPAN11

211

A1L157
MFRLEHGEADRSTLK

YJU2B

146

P13994
KDFMIVALDLLSGLA

TNPO1

646

Q92973
ILGVFMLHAFKDLDI

NIPAL4

336

Q0D2K0
MALFAGGKLRVHLDI

TMED4

121

Q7Z7H5
FLSKARETFLMAHDG

ZSWIM6

1171

Q9HCJ5
ELHERAMKFLLPFST

ZMYM6

1266

O95789
KEGLDIHSSMILRFL

ZZEF1

176

O43149
LFGQLLRLKMFREDH

TMEM117

91

Q9H0C3
LVEIEGVSKMAFRHL

ZNF131

71

P52739
HEVRMSHLEDILGKL

SUN1

431

O94901
TLTRLMAHLFGDELE

FARS2

246

O95363
ARLEKFMHFGAVLAL

WDR87

456

Q6ZQQ6
HLQDLMEGLTAKVFR

TOP1

576

P11387
MKHGDLHAFLLASRI

TYRO3

606

Q06418
MFLKDLRGHVELSEA

ZC3HAV1L

21

Q96H79
AEIISALMFLHDKGI

PRKCH

461

P24723
KHALRVLDMTGLLDD

LRRC14

111

Q15048
MDVFKILAAILHLGN

MYO5C

321

Q9NQX4
ELSHLSNRGARLFKM

MYOZ2

46

Q9NPC6
ALHLSKGMSIFLDIL

NECAB1

21

Q8N987