Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglycosyltransferase activity

GBE1 CERCAM ST6GAL1 UGT1A6

4.93e-04288264GO:0016757
GeneOntologyMolecularFunctionprotein transmembrane transporter activity

SEC61A2 SEC61A1

6.04e-0428262GO:0008320
GeneOntologyMolecularFunctionmacromolecule transmembrane transporter activity

SEC61A2 SEC61A1

8.91e-0434262GO:0022884
GeneOntologyMolecularFunctionprotein transporter activity

SEC61A2 SEC61A1

1.36e-0342262GO:0140318
GeneOntologyMolecularFunctionsignal sequence binding

SEC61A2 SEC61A1

2.00e-0351262GO:0005048
GeneOntologyMolecularFunctionhexosyltransferase activity

GBE1 CERCAM UGT1A6

2.53e-03211263GO:0016758
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

MED14 PPARG

2.85e-0361262GO:0030374
GeneOntologyBiologicalProcessSRP-dependent cotranslational protein targeting to membrane, translocation

SEC61A2 SEC61A1

3.62e-058242GO:0006616
GeneOntologyBiologicalProcesspost-translational protein targeting to membrane, translocation

SEC61A2 SEC61A1

3.62e-058242GO:0031204
GeneOntologyCellularComponentSec61 translocon complex

SEC61A2 SEC61A1

1.48e-055262GO:0005784
GeneOntologyCellularComponenttranslocon complex

SEC61A2 SEC61A1

2.22e-056262GO:0071256
GeneOntologyCellularComponentpericentriolar material

CEP152 TUBG2

5.51e-0428262GO:0000242
GeneOntologyCellularComponentrough endoplasmic reticulum membrane

SEC61A2 SEC61A1

5.92e-0429262GO:0030867
HumanPhenoHyperuricemia

PPARG LMAN1 SEC61A1

3.12e-053893HP:0002149
HumanPhenoIncreased circulating purine concentration

PPARG LMAN1 SEC61A1

6.75e-054993HP:0004368
HumanPhenoAbnormal circulating purine concentration

PPARG LMAN1 SEC61A1

1.01e-045693HP:0004352
DomainPlug_translocon

SEC61A2 SEC61A1

1.86e-062262PF10559
DomainSecY_su_dom

SEC61A2 SEC61A1

1.86e-062262IPR023201
DomainSecY_CS

SEC61A2 SEC61A1

1.86e-062262IPR030659
DomainSecY

SEC61A2 SEC61A1

1.86e-062262PF00344
DomainSECY_1

SEC61A2 SEC61A1

1.86e-062262PS00755
DomainSECY_2

SEC61A2 SEC61A1

1.86e-062262PS00756
DomainSecY/SEC61-alpha

SEC61A2 SEC61A1

1.86e-062262IPR002208
Domain-

SEC61A2 SEC61A1

1.86e-0622621.10.3370.10
DomainTranslocon_Sec61/SecY_plug_dom

SEC61A2 SEC61A1

1.86e-062262IPR019561
Domain-

ATP13A4 NT5DC2

3.56e-03642623.40.50.1000
DomainHAD-like_dom

ATP13A4 NT5DC2

5.38e-0379262IPR023214
DomainIg_E-set

GBE1 AREL1

9.15e-03104262IPR014756
Pubmed

Control of translocation through the Sec61 translocon by nascent polypeptide structure within the ribosome.

SEC61A2 SEC61A1

5.37e-07226218480044
Pubmed

Hsp90 modulates PPARγ activity in a mouse model of nonalcoholic fatty liver disease.

PPARG SEC61A1

5.37e-07226224927728
Pubmed

MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis.

MED14 PPARG

1.61e-06326220194623
Pubmed

The Sec61 complex is located in both the ER and the ER-Golgi intermediate compartment.

SEC61A2 SEC61A1

3.22e-06426210212142
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

MCM3 LMAN1 TUBG2 NT5DC2 UGT1A6 ASNS

4.72e-0660726639147351
Pubmed

No evidence that polymorphisms in CYP2C8, CYP2C9, UGT1A6, PPARdelta and PPARgamma act as modifiers of the protective effect of regular NSAID use on the risk of colorectal carcinoma.

PPARG UGT1A6

5.37e-06526216141797
Pubmed

Calnexin and other factors that alter translocation affect the rapid binding of ubiquitin to apoB in the Sec61 complex.

SEC61A2 SEC61A1

5.37e-0652629565615
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

HAT1 GBE1 MCM3 CERCAM LMAN1 SEC61A1 NT5DC2 CYFIP2

7.18e-06145126830550785
Pubmed

Expression Analyses of Cep152, a Responsible Gene Product for Autosomal Recessive Primary Microcephaly, during Mouse Brain Development.

CEP152 TUBG2

8.05e-06626235259752
Pubmed

Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress.

SEC61A2 SEC61A1

8.05e-06626216705175
Pubmed

Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha.

MED14 PPARG

1.93e-05926214636573
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

MED14 SEC61A2 MCM3 SEC61A1 PKP4 CYFIP2 ASNS

2.71e-05124726727684187
Pubmed

Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis.

MED14 PPARG

2.94e-051126212037571
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

MED14 HAT1 LMAN1 SEC61A1 ASNS

3.17e-0550326536217030
Pubmed

The role of assembly in insulin's biosynthesis.

SEC61A2 SEC61A1

3.53e-05122629631292
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

HAT1 MCM3 LMAN1 SEC61A1 NT5DC2 CYFIP2 ASNS

6.33e-05142526730948266
Pubmed

FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue.

PPARG TUBG2

9.12e-051926234348145
Pubmed

E3 ubiquitin ligase NEURL3 promotes innate antiviral response through catalyzing K63-linked ubiquitination of IRF7.

HAT1 MCM3

1.23e-042226235792897
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

MED14 HAT1 GBE1 PPARG LMAN1 ASNS

1.34e-04110326634189442
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

MED14 HAT1 MCM3 SEC61A1 ASNS

1.55e-0470426529955894
Pubmed

Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.

PPARG UGT1A6

1.60e-042526218992263
Pubmed

Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo.

CEP152 TUBG2

1.86e-042726224706806
Pubmed

Analysis of interaction partners of H4 histone by a new proteomics approach.

HAT1 MCM3

1.86e-042726219862764
Pubmed

CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination.

CEP152 TUBG2

1.86e-042726226158450
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

SLC6A6 CERCAM ST6GAL1 LMAN1 SYT12 SEC61A1

2.13e-04120126635696571
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

HAT1 SEC61A2 MCM3 SEC61A1 TUBG2 ASNS

2.72e-04125726637317656
Pubmed

Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.

PPARG UGT1A6

3.15e-043526218992148
Pubmed

Delineating WWOX Protein Interactome by Tandem Affinity Purification-Mass Spectrometry: Identification of Top Interactors and Key Metabolic Pathways Involved.

HAT1 SEC61A1 ASNS

5.60e-0421726330619736
Pubmed

FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates.

LMAN1 SEC61A1 TUBG2

6.06e-0422326334226595
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

SLC6A6 LMAN1 SEC61A1 NT5DC2 PKP4

6.20e-0495226538569033
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

SEC61A2 LMAN1 SEC61A1 NT5DC2 PKP4 ASNS

6.66e-04148726633957083
CytobandEnsembl 112 genes in cytogenetic band chr3p25

SLC6A6 PPARG

3.49e-03155262chr3p25
ToppCellCOVID-19_Severe-Plasmablast|COVID-19_Severe / disease group, cell group and cell class

ST6GAL1 LMAN1 SEC61A1 NT5DC2 ASNS

8.43e-081932658074bcede261b85f9ae03ee372bd6d4b40384537
ToppCellsevere-Plasmablast|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ST6GAL1 LMAN1 SEC61A1 NT5DC2 ASNS

9.58e-081982650b1620ad4352ee5d599a72931aaceab4ca407498
ToppCellsevere-Plasmablast|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ST6GAL1 LMAN1 SEC61A1 NT5DC2 ASNS

9.82e-081992656ee4c2e6049860071169366b7e662d5c1a3cc54b
ToppCelldroplet-Thymus-nan-21m-Myeloid-Plasma_cells_and_B_cells|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 LMAN1 SEC61A1 ASNS

2.45e-0616526421a82a975f550080b6674750b06212205cd16742
ToppCellBAL-Mild-cDC_4|Mild / Compartment, Disease Groups and Clusters

SEC61A2 GBE1 PKP4 CYFIP2

3.38e-0617926468511e87b12b8253de7771e5ccfc5869248b8450
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF38 GBE1 PKP4 CYFIP2

3.46e-061802649e09b3dfe344b5d50520711513d389865d73a861
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF38 ST6GAL1 PPARG CYFIP2

3.53e-06181264aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells|lymph-node_spleen / Manually curated celltypes from each tissue

CERCAM LMAN1 SEC61A1 NT5DC2

3.69e-06183264a6866951866373a1029e04818f4a4a31278c409d
ToppCell368C-Lymphocytic-Plasma_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CERCAM LMAN1 SEC61A1 NT5DC2

3.69e-06183264d91441cbf94f5c3b7c36f2ca3a46895870bd730f
ToppCell368C-Lymphocytic-Plasma_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CERCAM LMAN1 SEC61A1 NT5DC2

3.69e-061832647733cf919eda146efe41c93990658ce92db73aa8
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells|lymph-node_spleen / Manually curated celltypes from each tissue

CERCAM LMAN1 SEC61A1 NT5DC2

4.11e-06188264c7b1807c96f87fbcd37739a159cf00f9a1ff5d71
ToppCellSevere_COVID-19-B_cell|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

ST6GAL1 LMAN1 NT5DC2 ASNS

4.19e-0618926459ce8f15f413557d2059ee6b53ba5957b864cb8e
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 LMAN1 SEC61A1 ASNS

4.28e-06190264992539c380576bf810c00a5f926cf1ee7d57dcf5
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ST6GAL1 LMAN1 SEC61A1 NT5DC2

4.28e-0619026484eb7761f537d270673909a71d4f122e826769d5
ToppCellCOVID-19_Severe-Lymphoid_P|COVID-19_Severe / Disease group, lineage and cell class

ST6GAL1 LMAN1 SEC61A1 NT5DC2

4.46e-061922643d0240491296757b3125f6e861bbaca06bbc5068
ToppCellCOVID-19_Severe-Lymphoid_P-Plasmablast|COVID-19_Severe / Disease group, lineage and cell class

ST6GAL1 LMAN1 SEC61A1 NT5DC2

4.46e-0619226490af8dad4e6f80b5ecd62027deeb2e4cea6b24bb
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 LMAN1 SEC61A1 ASNS

4.46e-061922646417468829517a0f6e04e7e44eec1622001d4c5c
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ST6GAL1 LMAN1 SEC61A1 NT5DC2

4.56e-06193264227d82059a9f99937e0188ff57f2d0e485ebfe69
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ST6GAL1 LMAN1 SEC61A1 NT5DC2

4.56e-0619326438bb14df7f05c29565a1c7f175fafe636e543bf8
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ST6GAL1 LMAN1 SEC61A1 NT5DC2

4.56e-06193264ce3873ece35fd2155ea235cb3c8bcd235cc0ebde
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ST6GAL1 LMAN1 SEC61A1 NT5DC2

4.56e-061932648f57b0473a2c2c07f83e5fe70f16862b1bb3b514
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ST6GAL1 LMAN1 SEC61A1 NT5DC2

4.56e-061932643ba6d44248690b80f4caf791d463e60f1ab816c4
ToppCellnormal_Lymph_Node-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

CERCAM LMAN1 SEC61A1 NT5DC2

4.65e-061942641ca034f25a8fce503fb67654d7fa2a8ec71976be
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ST6GAL1 LMAN1 SEC61A1 NT5DC2

4.65e-061942643c30f86806f6a0f43e6103ad7009f4c6a90e011c
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ST6GAL1 LMAN1 SEC61A1 NT5DC2

4.75e-06195264fb3d6a3b10aedc7fdd9789b2c47b4e80fa8e411f
ToppCellCOVID_vent-Lymphocytic-Plasma_cell-IgA_Plasmablast|COVID_vent / Disease condition, Lineage, Cell class and subclass

ST6GAL1 LMAN1 SEC61A1 NT5DC2

4.94e-0619726499fe44ef42c65d24fe64947fd5bf6d91b9a4b2c3
ToppCellSevere-Plasmablast|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ST6GAL1 LMAN1 SEC61A1 NT5DC2

4.94e-061972641089aa7991812378668d0f3d57f8000e6245a713
ToppCellB_cells-Plasma_cells_and_plasmablasts|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

CERCAM LMAN1 SEC61A1 NT5DC2

4.94e-061972643b1c574b3d119b63967bb1306f0353ecc4c522f3
ToppCellmild-Plasmablast|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LMAN1 SEC61A1 NT5DC2 ASNS

4.94e-0619726421085d5e27b5a23a241a933058bb89f8a1fcf198
ToppCellB_cells-Plasmablasts|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CERCAM LMAN1 SEC61A1 NT5DC2

5.04e-06198264c6cab47885be74a64351f843a741dea6d911bde4
ToppCellCOVID_vent-Lymphocytic-Plasma_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

ST6GAL1 LMAN1 SEC61A1 NT5DC2

5.04e-06198264e84c5f712e1dea548d0e2aba6625598f9671d3a0
ToppCellmild-Plasmablast|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LMAN1 SEC61A1 NT5DC2 ASNS

5.04e-06198264b14b9e67815f93fac7bd8e5e6f1aa100951b4ac1
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GBE1 LMAN1 SEC61A1 ASNS

5.14e-061992649838fed26d8572ac29e7b5fd7220180f734d750a
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-B-Plasmablast|COVID-19_Severe / Disease, condition lineage and cell class

ST6GAL1 LMAN1 SEC61A1 NT5DC2

5.14e-06199264e6422b65e22e5aa8dfaebdae5be76dd78b978604
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF38 PKP4 CYFIP2

1.08e-0416026303b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCellHealthy_Control-Lymphoid-Plasma|Healthy_Control / Condition, Lineage, Cell class and cell subclass

SEC61A2 NT5DC2 ASNS

1.14e-041632632913ccdd4613472cd82077d4993e1d9f8b223398
ToppCellHealthy_Control-Lymphoid-Plasma-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

SEC61A2 NT5DC2 ASNS

1.14e-04163263b589ff57d58dcb215ee3b5a10d81f43e5752a196
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP13A4 PKP4 CYFIP2

1.14e-04163263cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCellNS-critical-d_0-4-Epithelial-unknown_epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ATP13A4 ZNF555 ASNS

1.20e-04166263dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HAT1 MCM3 SYT12

1.23e-04167263859dfe0764cb69de27e79e1c1aa65f9d538f79ea
ToppCell3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CEP152 TENM2 UGT1A6

1.25e-041682634e2e4c88ada772e9ba6e72c9ae3a05c063e93318
ToppCell3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CEP152 TENM2 UGT1A6

1.25e-04168263ee4dab089adef2f47a9d39d91934523331a8b81c
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 SEC61A1 ASNS

1.25e-04168263bc7d5f0e5d222922eaf1c8e8c87aab189209d6b6
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 CEP152 DENND6A

1.29e-041702636210ee3bf29059e6149c047bb7e02c5f59441519
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 SYT12 NT5DC2

1.36e-04173263d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 SYT12 NT5DC2

1.36e-041732633c852ffe22f4a5b632463086b08c669310684e80
ToppCellfacs-Marrow-T_cells-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 LMAN1 ASNS

1.36e-04173263e0cf99ddbe6e9eab05d7bf89e9aa124850c6a807
ToppCell10x5'-bone_marrow-Lymphocytic_B_plasma-Plasma_cells|bone_marrow / Manually curated celltypes from each tissue

CERCAM ST6GAL1 LMAN1

1.36e-04173263300904fd35536a69be81d76fe33fe16544523ceb
ToppCell10x5'-bone_marrow-Lymphocytic_B_plasma|bone_marrow / Manually curated celltypes from each tissue

CERCAM ST6GAL1 LMAN1

1.38e-04174263b1931028cf80af5eff6da15d7f0196205f17926f
ToppCellfacs-Marrow-T_cells-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 LMAN1 ASNS

1.38e-041742633b1ee39e85e5f0d6b17fb3051dbfae66cb2be6ee
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 LMAN1 ASNS

1.38e-041742633f4277763e312b46ebd4401ea4a2f5d4c850c768
ToppCellMultiple_Sclerosis-Lymphocyte-B-Plasmablast|Multiple_Sclerosis / Disease, Lineage and Cell Type

LMAN1 SEC61A1 NT5DC2

1.38e-04174263e8d2aa9505817aac3fe068080774d19458f07b01
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_plasma-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LMAN1 SEC61A1 NT5DC2

1.38e-04174263bdbaf805a94b2f5a0065933dab6bf84e3cabd525
ToppCelldroplet-Lung-nan-21m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 LMAN1 ASNS

1.38e-04174263fad66d1a8407574b6a835e0bdb824a53afa58650
ToppCellfacs-Marrow-T_cells-18m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 LMAN1 ASNS

1.41e-041752634be01bf30331162f1998216fb2871a4e626dc440
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-plasma_cell-plasma_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ST6GAL1 LMAN1 ASNS

1.41e-0417526328b29f844fa46fe579ddc19039fb2d9dc5f48f3b
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-plasma_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ST6GAL1 LMAN1 ASNS

1.41e-04175263ac96ca9ca309b0d72a2f5af6a3b02c7f80755750
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LMAN1 SEC61A1 NT5DC2

1.41e-041752633b5346fba617292de71963b6175e85a4f182fe30
ToppCellfacs-Marrow-T-cells-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMAN1 TUBG2 ASNS

1.41e-041752630a01e0104cfa3091bc05b0f1d087c941688169a5
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CEP152 PKP4 CYFIP2

1.41e-04175263a3f8c54c77bce9b035a4835945ab341909be4946
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LMAN1 SEC61A1 NT5DC2

1.43e-04176263dc4e939a07bad21ab36181f9588df3fa662f9a92
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 SEC61A1 ASNS

1.46e-0417726341cbb2c109eaa7be366fc0510cce64abc06837b4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF38 PKP4 CYFIP2

1.48e-041782634df6218b20c2f076c22346d23260964cc0d73e65
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 PPARG PKP4

1.51e-04179263fca111789d7354de7ae4cd38253aa0685c0cb2d2
ToppCellNS-critical-LOC-Lymphoid-PC|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ST6GAL1 LMAN1 NT5DC2

1.51e-04179263c044478525b8e7eedecddb924c1b049331180cb2
ToppCellILEUM-non-inflamed-(5)_Plasmablasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LMAN1 SEC61A1 NT5DC2

1.51e-0417926358c8996120637315dcbd1991a71516c09173051e
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 PPARG PKP4

1.51e-04179263c3e53a3b8e59f7245d737386a1dd0f9d7aa5fb61
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_late|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 SYT12 UGT1A6

1.53e-04180263255097d8eb244a32eb2ecd0e7e48e1a20bafb5cd
ToppCellBLOOD--(5)_Plasma| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LMAN1 SEC61A1 NT5DC2

1.53e-041802631ac0a0a715f4a36df0762bb0de44802d6ffa284c
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARG LMAN1 ASNS

1.53e-0418026354e3f289a37d4cfbfca4fb284c3b52e9c7d9da97
ToppCellBLOOD--(5)_Plasmablasts| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LMAN1 SEC61A1 NT5DC2

1.53e-041802634b9be1b19d4ecd0a3b924e4557a1ecfbcff2d705
ToppCellBAL-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ST6GAL1 LMAN1 ASNS

1.53e-041802636a777a308fa3160d31eda468db930e71862020b2
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARG LMAN1 ASNS

1.53e-04180263bfc8568d57034dd9c9e07edae94479a48ca0706d
ToppCelldroplet-Lung-LUNG-30m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF38 ATP13A4 SYT12

1.56e-04181263cadb18fc73031eb9f779599e15cd7861337fee78
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF38 ATP13A4 SYT12

1.56e-0418126385bec4d3f255f4c61c790325eeb50ad38f709ef2
ToppCellCOVID-19-B_cells-Plasma_cells|COVID-19 / group, cell type (main and fine annotations)

ST6GAL1 LMAN1 SEC61A1

1.61e-04183263130c109f63a5e3c8f83cb96e32f4addf513b6415
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B_plasma|lymph-node_spleen / Manually curated celltypes from each tissue

LMAN1 SEC61A1 NT5DC2

1.61e-04183263beadc69f511cf183e493cb445135f0748ab8b20e
ToppCell367C-Lymphocytic-Plasma_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CERCAM LMAN1 SEC61A1

1.63e-04184263fc708a5c8a7b19fab973c72dc4383a7d30f8b59a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 PPARG SYT12

1.63e-041842636b0c110d8930df99043c3b99cf4d873985126960
ToppCell367C-Lymphocytic-Plasma_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CERCAM LMAN1 SEC61A1

1.63e-0418426314a5288d861260f63fbe0cbea3569cf643e7597e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 PPARG SYT12

1.63e-0418426335928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 PPARG SYT12

1.63e-04184263f6148e9591e8845cc62668e49fd52755257cdc7e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF38 PKP4 CYFIP2

1.63e-04184263e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 LMAN1 SEC61A1

1.66e-04185263ff95a45b7cb782961bb8f008b6b507af2d4cb8b7
ToppCell10x5'-GI_large-bowel-Lymphocytic_B_plasma-Plasma_cells|GI_large-bowel / Manually curated celltypes from each tissue

CERCAM LMAN1 SEC61A1

1.66e-041852632cad994207c4afc9d70f4c2d243ffbbcdbba693e
ToppCellmetastatic_Lymph_Node-B_lymphocytes-MALT_B_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

LMAN1 SEC61A1 NT5DC2

1.66e-04185263bb87fa174f80706fe7be60d3b9fc3e2a6b373038
ToppCellcritical-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ST6GAL1 LMAN1 NT5DC2

1.66e-041852634a5d1d0a757f1f4fdb911be96ed90b52182c25f0
ToppCell10x5'-GI_large-bowel-Lymphocytic_B_plasma|GI_large-bowel / Manually curated celltypes from each tissue

CERCAM LMAN1 SEC61A1

1.66e-04185263989583c487d8c121e3731faf68f863ba43a582e6
ToppCellILEUM-non-inflamed-(5)_IgG_plasma_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ST6GAL1 LMAN1 SEC61A1

1.66e-0418526393b9a47357152ea95dfdfe8e7d111906a4adc551
ToppCellfacs-Heart-RV|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 PPARG PKP4

1.66e-041852637cf2b0db059605032bfae60cf1b93c4c62608f0c
ToppCellnormal_Lung-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

CERCAM LMAN1 NT5DC2

1.69e-04186263f4d72463c5f287da6436287eda0a349b4185841e
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Plasma_cells-IgM_plasma_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ST6GAL1 LMAN1 NT5DC2

1.69e-04186263a67e818c5ab682c2058fccc85f3fade0e11cb56e
ToppCellmild-Lymphocytic-Plasmablast|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

LMAN1 SEC61A1 NT5DC2

1.69e-04186263060510c21b1e0889b7a6eeb15821b9e2f03a0f99
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LMAN1 SEC61A1 NT5DC2

1.71e-0418726388d20f150df61ef0e3ee0c3e9895b094920c4b09
ToppCellfacs-Aorta-Heart-3m-Endothelial-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 PPARG PKP4

1.71e-04187263df0279b7e94e26f5541b0e2a0ce56befa96ec8ca
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF38 PKP4 CYFIP2

1.71e-041872637ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CERCAM ST6GAL1 LMAN1

1.71e-04187263c80e03d5aa498b4eecbc46565fabf9b5be10c71c
ToppCellMesenchymal_cells-Ng2+_MSCs|Mesenchymal_cells / Lineage and Cell class

SYT12 NT5DC2 CYFIP2

1.71e-04187263e899b906409f3fad69cb3d3c6432c3fd862ae3c1
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 ST6GAL1 CYFIP2

1.71e-04187263db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LMAN1 SEC61A1 NT5DC2

1.71e-04187263158c2c003fd225ba61793fb06eece232fb063d05
Diseasesocial interaction measurement

GBE1 TENM2 ASNS

7.72e-0594263EFO_0009592
DiseaseLipoidosis

PPARG ASNS

1.26e-0419262C0023794
Diseasedrug-induced liver injury

ST6GAL1 PPARG

2.04e-0424262EFO_0004228
Diseaseunipolar depression, bipolar disorder

AREL1 ATP13A4 TENM2

3.45e-04156263EFO_0003761, MONDO_0004985
Diseaseserum gamma-glutamyl transferase measurement

PPARG SYT12 TENM2 UGT1A6 CYFIP2

1.08e-03914265EFO_0004532
Diseasesmoking behavior, BMI-adjusted waist-hip ratio

PPARG NT5DC2

2.61e-0386262EFO_0004318, EFO_0007788
Diseasefeeling nervous measurement

AREL1 ASNS

2.67e-0387262EFO_0009597
Diseaseserum non-albumin protein measurement

ARHGEF38 ST6GAL1 PPARG

3.83e-03361263EFO_0004568
DiseaseBMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment

PPARG NT5DC2

3.86e-03105262EFO_0007788, EFO_0008007, EFO_0008343

Protein segments in the cluster

PeptideGeneStartEntry
FYSTKRPSYRAEQYP

PKP4

1171

Q99569
PFNTPKTKEGYYYRQ

ASNS

506

P08243
GLEPYNKVTYKPYQS

CEP152

186

O94986
FSKGKPFRQPTYTNY

ATP13A4

1056

Q4VNC1
VKGYVYSSFLKPYNP

ARHGEF38

631

Q9NXL2
YTPYTISPYNRKGSF

NXF3

66

Q9H4D5
NKPYPVRAKITYYQN

LMAN1

196

P49257
RDKPANVQPYYLYGS

CYFIP2

901

Q96F07
EVPNKPTQLSYKYYF

MED14

556

O60244
AANPVYGRYDQYKTP

MCM3

451

P25205
PYLKPYAVDFQRRYK

GBE1

36

Q04446
NYYVYPDKTRPRVSQ

HAT1

226

O14929
DSKPGVYTSYKPYLN

DENND6A

396

Q8IWF6
GLNVAYSPYYKIFQP

AREL1

146

O15033
PQGYYRRTAEYFPTK

CERCAM

186

Q5T4B2
PSPFPNYDYRYLQQK

SYT12

51

Q8IV01
KYVPLTYNKTYVYPN

SLC6A6

526

P31641
PIKSARYRGQYSSYP

SEC61A2

266

Q9H9S3
ASPPYYSEKTQLYNK

PPARG

111

P37231
YKTYRKLHPNQPFYI

ST6GAL1

281

P15907
GVNVSFVKYPKYGYT

TENM2

946

Q9NT68
IPPGVKQYEYNTYGK

ZNF555

136

Q8NEP9
PIKSARYRGQYNTYP

SEC61A1

266

P61619
YKYPEGIRKYDYNPS

NT5DC2

101

Q9H857
YPKKLVQTYSVFPYQ

TUBG2

161

Q9NRH3
KYYTRKIYPVPYDQE

UGT1A6

71

P19224
VPRFKNYPKDTYYPS

PIFO

116

Q8TCI5