Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	metalloendopeptidase activity	MMP27 MMP20 MMP15 MMP16 MMP17	2.69e-06	120	37	5	GO:0004222
GeneOntologyMolecularFunction	metalloaminopeptidase activity	MMP15 MMP16 MMP17	1.48e-05	26	37	3	GO:0070006
GeneOntologyMolecularFunction	metallopeptidase activity	MMP27 MMP20 MMP15 MMP16 MMP17	3.22e-05	200	37	5	GO:0008237
GeneOntologyMolecularFunction	aminopeptidase activity	MMP15 MMP16 MMP17	6.87e-05	43	37	3	GO:0004177
GeneOntologyMolecularFunction	zinc ion binding	MMP27 CUL9 ZMIZ1 MMP20 MMP15 MMP16 MMP17 GLI2	1.85e-04	891	37	8	GO:0008270
GeneOntologyMolecularFunction	transition metal ion binding	MMP27 XYLT2 CUL9 ZMIZ1 MMP20 MMP15 MMP16 MMP17 GLI2	2.49e-04	1189	37	9	GO:0046914
GeneOntologyMolecularFunction	metalloexopeptidase activity	MMP15 MMP16 MMP17	2.94e-04	70	37	3	GO:0008235
GeneOntologyMolecularFunction	exopeptidase activity	MMP15 MMP16 MMP17	1.10e-03	110	37	3	GO:0008238
GeneOntologyMolecularFunction	endopeptidase activity	MMP27 MMP20 MMP15 MMP16 MMP17	1.12e-03	430	37	5	GO:0004175
GeneOntologyMolecularFunction	peptidase activity	MMP27 PAN2 MMP20 MMP15 MMP16 MMP17	1.18e-03	654	37	6	GO:0008233
GeneOntologyMolecularFunction	enzyme activator activity	GNAS MMP15 BCR MMP16 MMP17 SYNGAP1	1.20e-03	656	37	6	GO:0008047
GeneOntologyBiologicalProcess	collagen catabolic process	MMP27 MMP20 MMP15 MMP16 MMP17	3.78e-08	53	37	5	GO:0030574
GeneOntologyBiologicalProcess	collagen metabolic process	MMP27 MMP20 MMP15 MMP16 MMP17 GLI2	2.39e-07	148	37	6	GO:0032963
GeneOntologyBiologicalProcess	animal organ morphogenesis	SLC4A10 ETV4 DGCR2 GNAS ZMIZ1 MMP20 BCR MMP16 GLI2 HAND2	5.66e-05	1269	37	10	GO:0009887
Domain	Pept_M10A_stromelysin-type	MMP27 MMP20 MMP15 MMP16 MMP17	1.94e-10	18	37	5	IPR016293
Domain	PG_binding_1	MMP27 MMP20 MMP15 MMP16 MMP17	3.49e-10	20	37	5	PF01471
Domain	Peptidoglycan-bd-like	MMP27 MMP20 MMP15 MMP16 MMP17	3.49e-10	20	37	5	IPR002477
Domain	Hemopexin-like_dom	MMP27 MMP20 MMP15 MMP16 MMP17	7.55e-10	23	37	5	IPR000585
Domain	Hemopexin	MMP27 MMP20 MMP15 MMP16 MMP17	7.55e-10	23	37	5	PF00045
Domain	HEMOPEXIN	MMP27 MMP20 MMP15 MMP16 MMP17	7.55e-10	23	37	5	PS00024
Domain	-	MMP27 MMP20 MMP15 MMP16 MMP17	7.55e-10	23	37	5	2.110.10.10
Domain	HEMOPEXIN_2	MMP27 MMP20 MMP15 MMP16 MMP17	7.55e-10	23	37	5	PS51642
Domain	Hemopexin-like_repeat	MMP27 MMP20 MMP15 MMP16 MMP17	7.55e-10	23	37	5	IPR018487
Domain	HX	MMP27 MMP20 MMP15 MMP16 MMP17	7.55e-10	23	37	5	SM00120
Domain	Pept_M10A	MMP27 MMP20 MMP15 MMP16 MMP17	7.55e-10	23	37	5	IPR021190
Domain	M10A_MMP	MMP27 MMP20 MMP15 MMP16 MMP17	7.55e-10	23	37	5	IPR033739
Domain	Peptidase_M10	MMP27 MMP20 MMP15 MMP16 MMP17	9.53e-10	24	37	5	PF00413
Domain	ZnMc	MMP27 MMP20 MMP15 MMP16 MMP17	2.64e-09	29	37	5	SM00235
Domain	Peptidase_Metallo	MMP27 MMP20 MMP15 MMP16 MMP17	2.64e-09	29	37	5	IPR006026
Domain	CYSTEINE_SWITCH	MMP27 MMP20 MMP15 MMP16 MMP17	1.64e-08	41	37	5	PS00546
Domain	Pept_M10A_Zn_BS	MMP27 MMP20 MMP15 MMP16	1.75e-08	15	37	4	IPR021158
Domain	Pept_M10_metallopeptidase	MMP27 MMP20 MMP15 MMP16 MMP17	2.10e-08	43	37	5	IPR001818
Domain	MetalloPept_cat_dom	MMP27 MMP20 MMP15 MMP16 MMP17	5.29e-07	81	37	5	IPR024079
Domain	-	MMP27 MMP20 MMP15 MMP16 MMP17	5.29e-07	81	37	5	3.40.390.10
Domain	ZINC_PROTEASE	MMP27 MMP20 MMP15 MMP16 MMP17	1.37e-06	98	37	5	PS00142
Domain	Hemopexin_CS	MMP27 MMP15 MMP16	4.77e-06	17	37	3	IPR018486
Domain	DUF3377	MMP15 MMP16	2.29e-05	4	37	2	PF11857
Domain	Pept_M10A_metallopeptidase_C	MMP15 MMP16	2.29e-05	4	37	2	IPR021805
Domain	Abhydrolase_1	SERHL2 SERHL	1.71e-03	31	37	2	PF00561
Domain	AB_hydrolase_1	SERHL2 SERHL	1.94e-03	33	37	2	IPR000073
Domain	LDLR_class-A_CS	DGCR2 MAMDC4	2.84e-03	40	37	2	IPR023415
Domain	Ldl_recept_a	DGCR2 MAMDC4	3.58e-03	45	37	2	PF00057
Domain	-	DGCR2 MAMDC4	3.74e-03	46	37	2	4.10.400.10
Domain	LDLRA_1	DGCR2 MAMDC4	4.07e-03	48	37	2	PS01209
Domain	LDrepeatLR_classA_rpt	DGCR2 MAMDC4	4.24e-03	49	37	2	IPR002172
Domain	LDLa	DGCR2 MAMDC4	4.24e-03	49	37	2	SM00192
Domain	LDLRA_2	DGCR2 MAMDC4	4.24e-03	49	37	2	PS50068
Pathway	WP_MATRIX_METALLOPROTEINASES	MMP27 MMP20 MMP15 MMP16 MMP17	3.52e-09	29	30	5	MM15981
Pathway	WP_MATRIX_METALLOPROTEINASES	MMP27 MMP20 MMP15 MMP16 MMP17	4.22e-09	30	30	5	M39652
Pathway	WP_CHRONIC_HYPERGLYCEMIA_IMPAIRMENT_OF_NEURON_FUNCTION	MMP27 MMP20 MMP15 MMP16 MMP17	3.97e-08	46	30	5	M46450
Pathway	REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES	MMP15 MMP16 MMP17	4.55e-05	33	30	3	M26976
Pathway	REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES	MMP15 MMP16 MMP17	6.98e-05	38	30	3	MM14611
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	MMP20 MMP15 MMP16 MMP17	9.45e-05	114	30	4	MM14571
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	MMP20 MMP15 MMP16 MMP17	2.09e-04	140	30	4	M587
Pubmed	Matrix metalloproteinases.	MMP27 MMP20 MMP15 MMP16 MMP17	2.67e-11	22	37	5	10419448
Pubmed	Functional interactions between matrix metalloproteinases and glycosaminoglycans.	MMP27 MMP20 MMP15 MMP16 MMP17	2.67e-11	22	37	5	23421805
Pubmed	Structural differences of matrix metalloproteinases. Homology modeling and energy minimization of enzyme-substrate complexes.	MMP20 MMP15 MMP16 MMP17	3.56e-10	11	37	4	10949161
Pubmed	Matrix metalloproteinases in tumor invasion.	MMP20 MMP15 MMP16 MMP17	1.95e-09	16	37	4	10949577
Pubmed	Expression pattern of four membrane-type matrix metalloproteinases in the normal and diseased mouse mammary gland.	MMP15 MMP16 MMP17	4.43e-09	4	37	3	15895410
Pubmed	mRNA expression of the five membrane-type matrix metalloproteinases MT1-MT5 in human prostatic cell lines and their down-regulation in human malignant prostatic tissue.	MMP15 MMP16 MMP17	1.11e-08	5	37	3	12661033
Pubmed	Matrix metalloproteinases 2 and 9 are dispensable for pancreatic islet formation and function in vivo.	MMP20 MMP15 MMP16 MMP17	1.13e-08	24	37	4	15734845
Pubmed	The low density lipoprotein receptor-related protein LRP is regulated by membrane type-1 matrix metalloproteinase (MT1-MMP) proteolysis in malignant cells.	MMP15 MMP16 MMP17	2.21e-08	6	37	3	14645246
Pubmed	Membrane-type matrix metalloproteinases: Their functions and regulations.	MMP15 MMP16 MMP17	3.87e-08	7	37	3	25794647
Pubmed	Identification of Serhl, a new member of the serine hydrolase family induced by passive stretch of skeletal muscle in vivo.	SERHL2 SERHL	1.10e-06	2	37	2	11352564
Pubmed	Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family.	MMP15 MMP16	1.10e-06	2	37	2	7559440
Pubmed	Genes of the membrane-type matrix metalloproteinase (MT-MMP) gene family, MMP14, MMP15, and MMP16, localize to human chromosomes 14, 16, and 8, respectively.	MMP15 MMP16	1.10e-06	2	37	2	9070935
Pubmed	A cancer cell metalloprotease triad regulates the basement membrane transmigration program.	MMP15 MMP16	3.30e-06	3	37	2	16983145
Pubmed	Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization.	MMP15 MMP16	3.30e-06	3	37	2	9119382
Pubmed	Changes in the expression of membrane type-matrix metalloproteinases genes (MMP14, MMP15, MMP16, MMP24) during treatment and their potential impact on the survival of patients with non-small cell lung cancer (NSCLC).	MMP15 MMP16	6.60e-06	4	37	2	35062057
Pubmed	Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.	MMP15 MMP16 MMP17	7.72e-06	36	37	3	20587546
Pubmed	Netrin 1-Mediated Role of the Substantia Nigra Pars Compacta and Ventral Tegmental Area in the Guidance of the Medial Habenular Axons.	ROBO3 GLI2	1.10e-05	5	37	2	34169076
Pubmed	MT3-MMP Promotes Excitatory Synapse Formation by Promoting Nogo-66 Receptor Ectodomain Shedding.	MMP15 MMP16	1.10e-05	5	37	2	29196321
Pubmed	GLI transcriptional repression is inert prior to Hedgehog pathway activation.	GLI2 HAND2	3.07e-05	8	37	2	35145123
Pubmed	Differential expression of matrix metalloproteinases and their inhibitors in human and mouse lung development.	MMP20 MMP15	3.95e-05	9	37	2	16113801
Pubmed	Genes that distinguish physiological and pathological angiogenesis.	ETV4 PTPRN	4.93e-05	10	37	2	17560335
Pubmed	Increasing Sufu gene dosage reveals its unorthodox role in promoting polydactyly and medulloblastoma tumorigenesis.	GLI2 HAND2	4.93e-05	10	37	2	38358805
Pubmed	Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks.	GLI2 HAND2	4.93e-05	10	37	2	33006313
Pubmed	The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression.	ROBO3 GLI2	4.93e-05	10	37	2	30843071
Pubmed	Limb anterior-posterior polarity integrates activator and repressor functions of GLI2 as well as GLI3.	GLI2 HAND2	4.93e-05	10	37	2	22841643
Pubmed	A mouse splice-site mutant and individuals with atypical chromosome 22q11.2 deletions demonstrate the crucial role for crkl in craniofacial and pharyngeal development.	ETV4 HAND2	4.93e-05	10	37	2	25565927
Pubmed	The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma.	GNAS GLI2	6.02e-05	11	37	2	25150496
Pubmed	Mapping of two mouse membrane-type matrix metalloproteinase (MT-MMP) genes, Mmp15 and Mmp16, to mouse chromosomes 8 and 4, respectively.	MMP15 MMP16	6.02e-05	11	37	2	9653660
Pubmed	Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb.	ETV4 HAND2	6.02e-05	11	37	2	19386268
Pubmed	Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1.	GLI2 HAND2	7.22e-05	12	37	2	11389830
Pubmed	Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo.	ETV4 HAND2	7.22e-05	12	37	2	12490567
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	RBM6 PAN2 CUL9 COQ8A	7.57e-05	212	37	4	33853758
Pubmed	Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development.	GLI2 HAND2	8.53e-05	13	37	2	25448692
Pubmed	T396I mutation of mouse Sufu reduces the stability and activity of Gli3 repressor.	GLI2 HAND2	8.53e-05	13	37	2	25760946
Pubmed	Developmental guidance of the retroflex tract at its bending point involves Robo1-Slit2-mediated floor plate repulsion.	ROBO3 GLI2	8.53e-05	13	37	2	25366972
Pubmed	Sufu and Kif7 in limb patterning and development.	GLI2 HAND2	9.94e-05	14	37	2	25581370
Pubmed	Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification.	GNAS GLI2	9.94e-05	14	37	2	24076664
Pubmed	Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb.	ETV4 HAND2	9.94e-05	14	37	2	20826535
Pubmed	Membrane-type MMPs are indispensable for placental labyrinth formation and development.	MMP15 MMP16	9.94e-05	14	37	2	20858856
Pubmed	Genetic interaction between Gli3 and Ezh2 during limb pattern formation.	GLI2 HAND2	9.94e-05	14	37	2	29729398
Pubmed	Twist1 activity thresholds define multiple functions in limb development.	ETV4 HAND2	1.15e-04	15	37	2	20732316
Pubmed	Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice.	ETV4 HAND2	1.15e-04	15	37	2	21177346
Pubmed	ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex.	MMP15 MMP17	1.15e-04	15	37	2	38871984
Pubmed	Functional redundancy of frizzled 3 and frizzled 6 in planar cell polarity control of mouse hair follicles.	SERHL2 SERHL	1.15e-04	15	37	2	30237242
Pubmed	Enpp1 inhibits ectopic joint calcification and maintains articular chondrocytes by repressing hedgehog signaling.	GNAS GLI2	1.31e-04	16	37	2	30111653
Pubmed	Association of matrix metalloproteinase gene polymorphisms with refractive error in Amish and Ashkenazi families.	MMP27 MMP20	1.31e-04	16	37	2	20484597
Pubmed	Expression dynamics of metalloproteinases during mandibular bone formation: association with Myb transcription factor.	MMP15 MMP16	1.31e-04	16	37	2	37701782
Pubmed	Suppressor of Fused Is Required for Determining Digit Number and Identity via Gli3/Fgfs/Gremlin.	GLI2 HAND2	1.31e-04	16	37	2	26001200
Pubmed	A switch from low to high Shh activity regulates establishment of limb progenitors and signaling centers.	GLI2 HAND2	1.31e-04	16	37	2	24726283
Pubmed	Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is Required for Axon Guidance in the Spinal Cord.	ROBO3 GLI2	1.31e-04	16	37	2	28434801
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RBM6 GNAS ZMIZ1 COQ8A BCR MMP16 GLI2 NOTCH3	1.41e-04	1489	37	8	28611215
Pubmed	Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3.	ROBO3 GLI2	1.48e-04	17	37	2	26257608
Pubmed	G-Protein α-Subunit Gsα Is Required for Craniofacial Morphogenesis.	GNAS HAND2	1.48e-04	17	37	2	26859889
Pubmed	Gata6-Dependent GLI3 Repressor Function is Essential in Anterior Limb Progenitor Cells for Proper Limb Development.	ETV4 HAND2	1.67e-04	18	37	2	27352137
Pubmed	Expression analysis of the entire MMP and TIMP gene families during mouse tissue development.	MMP27 MMP20	1.86e-04	19	37	2	15063736
Pubmed	Loss of dynein-2 intermediate chain Wdr34 results in defects in retrograde ciliary protein trafficking and Hedgehog signaling in the mouse.	GLI2 HAND2	2.07e-04	20	37	2	28379358
Pubmed	Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome.	GLI2 HAND2	2.07e-04	20	37	2	21045211
Pubmed	Msx1 and Msx2 in limb mesenchyme modulate digit number and identity.	ETV4 HAND2	2.07e-04	20	37	2	21465616
Pubmed	A role for the primary cilium in Notch signaling and epidermal differentiation during skin development.	GLI2 NOTCH3	2.28e-04	21	37	2	21703454
Pubmed	Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis.	GLI2 HAND2	2.28e-04	21	37	2	32855417
Pubmed	Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia.	GLI2 NOTCH3	2.28e-04	21	37	2	22935613
Pubmed	FGF-regulated Etv genes are essential for repressing Shh expression in mouse limb buds.	ETV4 HAND2	2.28e-04	21	37	2	19386269
Pubmed	Cbln1 regulates axon growth and guidance in multiple neural regions.	ROBO3 GLI2	2.51e-04	22	37	2	36395107
Pubmed	GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation.	GLI2 NOTCH3	2.99e-04	24	37	2	32497091
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	NUDT19 CUL9 GNAS BCR	3.36e-04	313	37	4	38270169
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	CUL9 CEP152 ZMIZ1	3.61e-04	130	37	3	12421765
Pubmed	SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.	ETV4 IL17RC TMEM104 PIR FBXO46 HAND2	3.78e-04	915	37	6	32393512
Pubmed	Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ.	MMP20 GLI2	4.09e-04	28	37	2	32674056
Pubmed	Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.	PAN2 ZMIZ1 GLI2	4.12e-04	136	37	3	25429064
Pubmed	Anteroposterior Limb Skeletal Patterning Requires the Bifunctional Action of SWI/SNF Chromatin Remodeling Complex in Hedgehog Pathway.	GLI2 HAND2	4.39e-04	29	37	2	26959361
Pubmed	pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development.	GLI2 NOTCH3	4.70e-04	30	37	2	17257418
Pubmed	Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway.	ETV4 GLI2	4.70e-04	30	37	2	35682694
Pubmed	Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling.	GLI2 HAND2	5.35e-04	32	37	2	19286674
Pubmed	Reevaluating human gene annotation: a second-generation analysis of chromosome 22.	SERHL2 SERHL	5.69e-04	33	37	2	12529303
Pubmed	Human transcription factor protein interaction networks.	RBM6 ETV4 CUL9 CEP152 ZMIZ1 INO80D GLI2	6.79e-04	1429	37	7	35140242
Pubmed	GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis.	GLI2 HAND2	7.16e-04	37	37	2	22465667
Pubmed	Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice.	GLI2 NOTCH3	7.16e-04	37	37	2	26697723
Pubmed	The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development.	COQ8A HAND2	7.56e-04	38	37	2	33913477
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	XYLT2 MMP16 MMP17 ZC3H6 ZNF316	7.76e-04	689	37	5	36543142
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	MMP27 MMP20 MMP15 MMP16 MMP17	1.00e-03	730	37	5	34857952
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DGCR2 CUL9 BCR MMP17 FBXO46 ZNF316	1.02e-03	1105	37	6	35748872
Pubmed	Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.	MMP15 MMP16 MMP17	1.02e-03	186	37	3	20452482
Pubmed	A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).	MMP15 MMP16 MMP17	1.02e-03	186	37	3	20673868
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	ETV4 ZMIZ1 GLI2 NOTCH3	1.05e-03	424	37	4	21731673
Pubmed	A comprehensive analysis of 22q11 gene expression in the developing and adult brain.	DGCR2 BCR	1.06e-03	45	37	2	14614146
Interaction	MMP24 interactions	MMP27 MMP20 MMP15 MMP16 MMP17	1.80e-10	19	37	5	int:MMP24
Interaction	MMP16 interactions	MMP27 MMP20 MMP16 MMP17	2.89e-08	18	37	4	int:MMP16
Interaction	MMP8 interactions	MMP27 MMP20 MMP15 MMP16	1.18e-07	25	37	4	int:MMP8
Interaction	MMP1 interactions	MMP27 MMP16 MMP17	4.24e-05	37	37	3	int:MMP1
Cytoband	Ensembl 112 genes in cytogenetic band chr11q22	MMP27 MMP20	3.40e-03	107	37	2	chr11q22
GeneFamily	Endogenous ligands\|Matrix metallopeptidases	MMP27 MMP20 MMP15 MMP16 MMP17	2.54e-10	24	28	5	891
Coexpression	NABA_ECM_REGULATORS	MMP27 MMP20 MMP15 MMP16 MMP17	2.04e-05	238	37	5	M3468
Coexpression	NABA_ECM_REGULATORS	MMP27 MMP20 MMP15 MMP16 MMP17	2.20e-05	242	37	5	MM17062
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-4\|TCGA-Colorectal / Sample_Type by Project: Shred V9	NUDT19 ETV4 SERHL ZNF316	3.96e-06	129	37	4	003a3202053986c2eb10d5e84b90ab33b7ee37e3
ToppCell	3'_v3-bone_marrow-Mast-Mast_cell_lympho\|bone_marrow / Manually curated celltypes from each tissue	XYLT2 ZMIZ1 ROBO3 SYNGAP1	1.18e-05	170	37	4	4dedf482cd4521b3f87d2b5ae80f7a3ea8686a15
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ROBO3 PIR BCR NOTCH3	1.26e-05	173	37	4	4f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ROBO3 PIR BCR NOTCH3	1.26e-05	173	37	4	9bbea566964281f47bf75d665b7d69ba8326e207
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ETV4 GNAS BCR NOTCH3	1.79e-05	189	37	4	26cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ETV4 GNAS BCR NOTCH3	1.82e-05	190	37	4	2ab604d35456beba71c25511e0f819000e6642d2
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-suprabasal_interpapillary\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL17RC PIR NOTCH3 TFR2	1.90e-05	192	37	4	44cb225392c8d07150955ecf203fbdf6021c9790
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-keratinocyte\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL17RC PIR NOTCH3 TFR2	2.02e-05	195	37	4	c54b19e31efe2c9ae690062569da7c0f1120a1d8
ToppCell	COVID-19_Severe-MAIT\|World / disease group, cell group and cell class	SLC4A10 NOTCH3 SYNGAP1	2.35e-04	145	37	3	8d63f97812f63329ef9c940b291dc5a1c4d90690
ToppCell	COVID-19_Severe-MAIT\|COVID-19_Severe / disease group, cell group and cell class	SLC4A10 NOTCH3 SYNGAP1	2.60e-04	150	37	3	923ea7ecc0aa05fb0396082cd9c3d1594135f1e0
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GNAS MMP16 MMP17	2.75e-04	153	37	3	61fe71e32fc9c8cad875bc087aad0b0ff680bf45
ToppCell	severe_COVID-19-pDC\|World / disease group, cell group and cell class (v2)	SERHL2 TTC39A MMP15	3.08e-04	159	37	3	e1c48c4ceda116826819ff9adeed7bad6a58844d
ToppCell	severe_COVID-19-pDC\|severe_COVID-19 / disease group, cell group and cell class (v2)	SERHL2 TTC39A MMP15	3.08e-04	159	37	3	ea5088d27e42b8850455764d53b757ea8d8f14bc
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GNAS ROBO3 BCR	3.20e-04	161	37	3	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GNAS ROBO3 BCR	3.20e-04	161	37	3	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GNAS ROBO3 BCR	3.20e-04	161	37	3	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GNAS NOTCH3 SYNGAP1	3.25e-04	162	37	3	c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GNAS NOTCH3 SYNGAP1	3.25e-04	162	37	3	f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GNAS NOTCH3 SYNGAP1	3.25e-04	162	37	3	5d902bb31e691aea9749617cc88303c2448f24b8
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GNAS ROBO3 BCR	3.25e-04	162	37	3	96c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	PAN2 INO80D SYNGAP1	3.49e-04	166	37	3	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ETV4 PTPRN HAND2	3.56e-04	167	37	3	1adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ETV4 PTPRN HAND2	3.56e-04	167	37	3	743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	ROBO3 MMP16 NOTCH3	3.56e-04	167	37	3	c4e321bb87512ea839f324c92c0f1afea891483f
ToppCell	droplet-Lung-LUNG-30m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO3 PIR BCR	3.62e-04	168	37	3	e156297a7515e785a9e79a9676700bd3a9d92b98
ToppCell	3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAN2 ETV4 CEP152	3.62e-04	168	37	3	4e2e4c88ada772e9ba6e72c9ae3a05c063e93318
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO3 PIR BCR	3.62e-04	168	37	3	32e0bc0873baa13027241063283ef26d2aab56f5
ToppCell	3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAN2 ETV4 CEP152	3.62e-04	168	37	3	ee4dab089adef2f47a9d39d91934523331a8b81c
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAN2 PIR MMP16	3.68e-04	169	37	3	58136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCell	droplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO3 PIR NOTCH3	3.68e-04	169	37	3	7962165cab84af73d20b56eb70b1ed87c94025ef
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAN2 PIR MMP16	3.68e-04	169	37	3	04c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO3 PIR NOTCH3	3.81e-04	171	37	3	4e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP27 ETV4 MMP17	3.88e-04	172	37	3	f814b6134ad608015765399d54cc1e5e1873ed34
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAN2 MMP16 FBXO46	3.88e-04	172	37	3	8a6a2b4c6654bc976e60a02d0e7303a9071ed55f
ToppCell	Endothelial-Endothelial-G\|Endothelial / shred on cell class and cell subclass (v4)	CUL9 GNAS BCR	3.88e-04	172	37	3	644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GNAS GLI2 NOTCH3	4.01e-04	174	37	3	f230d23618a6487f2664efb2c677e0a4559e2bf4
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MMP15 MMP17 HAND2	4.01e-04	174	37	3	412ccc099028a372b9d953363984c2da54b2187f
ToppCell	droplet-Spleen-nan-3m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO3 PIR BCR	4.08e-04	175	37	3	21bc0e59a9509d38751ce6aad2325f341bc70eff
ToppCell	PCW_13-14-Neuronal-Neuronal_postreplicative-neuro_NA\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MMP15 MMP17 HAND2	4.22e-04	177	37	3	8c78f7de091f16e86e326a73c9f1429e0232821f
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MMP15 MMP17 HAND2	4.22e-04	177	37	3	59726bfd98f656fdcedf448a7e2e76a9bfad8285
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	DGCR2 BCR INO80D	4.22e-04	177	37	3	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|343B / Donor, Lineage, Cell class and subclass (all cells)	SLC4A10 FBXO46 INO80D	4.29e-04	178	37	3	5289ac61637224ae70ffbc2d164d73116f10af40
ToppCell	wk_08-11-Epithelial-PNS-Late_Schwann\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MMP15 MMP17 HAND2	4.29e-04	178	37	3	a7301c0bba03d10feacc02e3f929d9a9235fd25b
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MMP16 GLI2 NOTCH3	4.29e-04	178	37	3	e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV4 NOTCH3 TFR2	4.36e-04	179	37	3	e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_Erythro-Mega\|lymph-node_spleen / Manually curated celltypes from each tissue	SERHL2 IL17RC PIR	4.36e-04	179	37	3	957c08ad4b46eb4cc1717c45056fc3db50015fdc
ToppCell	droplet-Spleen-nan-24m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO3 PIR BCR	4.36e-04	179	37	3	d50d29f26d5a2cd8c4cd4e1244e1bb8de072d159
ToppCell	facs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO3 PIR BCR	4.43e-04	180	37	3	bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCell	facs-Marrow-B-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO3 PIR BCR	4.43e-04	180	37	3	82965ed1b72a1873c24dd4553d39681596057316
ToppCell	E18.5-samps-Mesenchymal-Pericyte\|E18.5-samps / Age Group, Lineage, Cell class and subclass	GNAS BCR NOTCH3	4.43e-04	180	37	3	0b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(INS+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTC39A GNAS PTPRN	4.43e-04	180	37	3	0c5d9245b8a7cc34ad52522d31559906cda55bdf
ToppCell	BAL-Control-cDC_8\|Control / Compartment, Disease Groups and Clusters	TMEM104 ROBO3 PIR	4.50e-04	181	37	3	f370161afef2ec827a7b194c06abb9ac1a507cbb
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SERHL2 TTC39A MMP15	4.57e-04	182	37	3	9bbe8062aa562dc3b9c299581faf6ebbcb72a9f7
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MMP15 MMP17 HAND2	4.57e-04	182	37	3	f7f9be9c7ef8da9864d6aefe20043b26e1bb8697
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MMP15 MMP17 HAND2	4.57e-04	182	37	3	b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SERHL2 TTC39A MMP15	4.57e-04	182	37	3	4602a98df7045e2c70b7560abfba9b444fbd5d30
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MMP15 MMP17 HAND2	4.65e-04	183	37	3	f517215ff45dec914af52dfdbc4579c19654c3aa
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV4 MMP15 MMP16	4.72e-04	184	37	3	8d86e125257ff1d3af8d90577a8b3f0321eca21c
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV4 MMP15 MMP16	4.72e-04	184	37	3	278a7ed764c326450cb70e69ed2175980eaf5fe0
ToppCell	Differ-KC\|World / shred by cell class for mouse tongue	IL17RC PIR NOTCH3	4.95e-04	187	37	3	08f70e5103c6dd96f439f0cceda878963d26850d
ToppCell	PCW_05-06-Neuronal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MMP15 MMP17 HAND2	4.95e-04	187	37	3	03a2ed85b171c887d4f3b0f4fe2e1cb4a853e658
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV4 MMP15 MMP16	5.02e-04	188	37	3	a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV4 MMP15 MMP16	5.02e-04	188	37	3	053c251d3ddbeb866f34565aefca4535517b4387
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV4 MMP15 MMP16	5.02e-04	188	37	3	7471c194276161422326647f09022e94f3d1640c
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GNAS BCR NOTCH3	5.02e-04	188	37	3	a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV4 MMP15 MMP16	5.02e-04	188	37	3	c8530c9ff98666c64a94683261af4288cb790a7e
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-chondrocyte\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MMP16 GLI2 NOTCH3	5.02e-04	188	37	3	c9270517e6940e9793586f67f02431210552f278
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUDT19 ETV4 COQ8A	5.10e-04	189	37	3	be09a116ce0ea9ddfa0974806c6f805438e44660
ToppCell	control-immature_Neutrophil\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SLC4A10 DGCR2 TMEM104	5.10e-04	189	37	3	bdfd120900ba58d5e54765f7b576e1f8cc2401bf
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GNAS BCR NOTCH3	5.18e-04	190	37	3	951e067d14412db67dc3babcdf61e41717d7b429
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GNAS BCR NOTCH3	5.18e-04	190	37	3	979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ETV4 GNAS NOTCH3	5.18e-04	190	37	3	84fbd5664ec886120963d4f50dfa1fd1851d36c1
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV4 MMP15 MMP16	5.26e-04	191	37	3	ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV4 MMP15 MMP16	5.26e-04	191	37	3	478e8341ee03b05501e2233e02cef5f97492c95d
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GNAS BCR NOTCH3	5.26e-04	191	37	3	2ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCell	11.5-Airway-Epithelial-Epithelial\|Airway / Age, Tissue, Lineage and Cell class	PTPRN MMP17 HAND2	5.34e-04	192	37	3	a77d3692ff02ef7e066a9bd9e22725055a25c4d4
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GNAS NOTCH3 TFR2	5.34e-04	192	37	3	2dee0402e97e48157e0bc01bcc8034f1645dfb7b
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ETV4 GNAS MMP16	5.42e-04	193	37	3	efa91167dc7a59bf32addf90ffb7bf070b2a0151
ToppCell	368C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TTC39A ROBO3 MAMDC4	5.42e-04	193	37	3	5f5904cec8b2967154ef2eab3c48f51df53aca4a
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MMP15 MMP17 HAND2	5.42e-04	193	37	3	d5930f7bd9b299f792212d40a3272a37adf64a82
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GNAS BCR NOTCH3	5.59e-04	195	37	3	7a32a8535c29b819dacba901d0658280a2631c94
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GNAS BCR NOTCH3	5.59e-04	195	37	3	4a5d2f62aad5817d077177bf8b4ff0e46d3b8d97
ToppCell	15-Airway-Epithelial-Epithelial\|Airway / Age, Tissue, Lineage and Cell class	MMP15 PTPRN HAND2	5.59e-04	195	37	3	56356a9aeb67b50a74425be2cd9c50d31416c1b3
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIR BCR HAND2	5.67e-04	196	37	3	7d5eaed189aa6116f3799be010139fb675ec65e0
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GNAS BCR NOTCH3	5.67e-04	196	37	3	6708026bafd19c35c5c4e81911344d36a0f508cd
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MMP15 MMP17 HAND2	5.84e-04	198	37	3	c8272ac4d90f2367f538f66db40de911ad73ea7f
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MMP15 MMP17 HAND2	5.84e-04	198	37	3	52ddc1f1ed4ac4c3bac794c90b8feb03e3c221c4
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MMP15 MMP17 HAND2	5.84e-04	198	37	3	36c97eb71b89bac01cabd6a8b728e5a20e52d2a3
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MMP15 MMP17 HAND2	5.84e-04	198	37	3	50dfe6efca76ea9683a19b6bff59cb5030d346f1
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MMP15 MMP17 HAND2	5.84e-04	198	37	3	5b9a7b9f53a3d9cf8d6e6a7c1c94514b22cf9fa8
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MMP16 NOTCH3 HAND2	5.84e-04	198	37	3	8602a518b5913625b1dd3cbc3c7e6efde0d5d942
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MMP16 NOTCH3 HAND2	5.84e-04	198	37	3	55d2ed345101bec4b73f1242ba8c4d73073b7e88
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MMP15 MMP17 HAND2	5.93e-04	199	37	3	ce699726ac4825c65bf934cb9a76202ad7340596
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MMP15 MMP17 HAND2	5.93e-04	199	37	3	8d13a9ea87f685b5a34b84c4571db6be753cf2d9
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MMP15 MMP17 HAND2	5.93e-04	199	37	3	f1d5808ccb1d5d4e2d34f864e705e2484000e88f
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MMP15 MMP17 HAND2	5.93e-04	199	37	3	a816b0eed80530113b7e720bbd2311a544ed8ed1
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MMP15 MMP17 HAND2	6.01e-04	200	37	3	de55100e98d3e9b8a74e37aebcd3afa2b0996527
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MMP16 GLI2 NOTCH3	6.01e-04	200	37	3	ad3fb8ef0be45032369d1325024787fbe1dfb8d6
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Artery\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PIR BCR MMP16	6.01e-04	200	37	3	b1ff8d61b567f85006d6d20093f9c803b6d34674
Drug	DA-125	MMP27 MMP20 MMP15 MMP16 MMP17	5.49e-10	26	37	5	CID000114758
Drug	AC1L9M3B	MMP27 GNAS MMP20 MMP15 MMP16 MMP17	6.26e-10	61	37	6	CID000448562
Drug	mercuric acetate	MMP27 MMP20 MMP15 MMP16 MMP17	1.18e-09	30	37	5	CID000015337
Drug	malolactomycin D	MMP27 MMP20 MMP15 MMP16 MMP17	1.67e-09	32	37	5	CID006449115
Drug	4-aminophenyl	MMP27 MMP20 MMP15 MMP16 MMP17	5.18e-08	62	37	5	CID000181201
Drug	diacerein	MMP27 MMP20 MMP15 MMP16 MMP17	5.62e-08	63	37	5	CID000026248
Drug	AC1L1GXT	MMP27 MMP20 MMP15 MMP16 MMP17	1.27e-07	74	37	5	CID000003890
Drug	A0395	MMP27 MMP20 MMP15 MMP16 MMP17	1.36e-07	75	37	5	CID009906466
Drug	AC1NSU5S	MMP27 MMP20 MMP15 MMP16 MMP17	1.36e-07	75	37	5	CID005316299
Drug	Citalopram hydrobromide [59729-32-7]; Down 200; 1uM; PC3; HT_HG-U133A	XYLT2 DGCR2 IL17RC GNAS ROBO3 INO80D	7.23e-07	197	37	6	3820_DN
Drug	(R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; MCF7; HT_HG-U133A	CUL9 IL17RC GNAS ROBO3 MMP16 INO80D	7.45e-07	198	37	6	6096_DN
Drug	Indoprofen [31842-01-0]; Down 200; 14.2uM; MCF7; HT_HG-U133A	SERHL2 DGCR2 CUL9 CEP152 MMP15 INO80D	7.67e-07	199	37	6	3345_DN
Drug	quinacrine	MMP27 GNAS MMP20 MMP15 MMP16 MMP17	2.45e-06	243	37	6	CID000000237
Drug	pirfenidone	MMP27 MMP20 MMP15 MMP16 MMP17	2.84e-06	138	37	5	CID000040632
Drug	MMI270	MMP15 MMP16 MMP17	3.17e-06	18	37	3	CID000446504
Drug	isoflavone	MMP27 MMP20 MMP15 MMP16 MMP17	5.01e-06	155	37	5	CID000072304
Drug	dioxane	MMP27 MMP20 MMP15 BCR MMP16 MMP17	5.31e-06	278	37	6	CID000031275
Drug	carvedilol	MMP27 MMP20 MMP15 MMP16 MMP17	6.03e-06	161	37	5	CID000002585
Drug	titanium	MMP27 MMP20 MMP15 MMP16 MMP17	7.86e-06	170	37	5	CID000023963
Drug	Pro-leu-gly	MMP15 MMP16 MMP17	1.00e-05	26	37	3	CID000169533
Drug	AC1L1DD6	MMP27 MMP20 MMP15 MMP16 MMP17	1.01e-05	179	37	5	CID000002299
Drug	C768-0445; Up 200; 10uM; MCF7; HT_HG-U133A_EA	PAN2 CUL9 MMP15 COQ8A FBXO46	1.31e-05	189	37	5	973_UP
Drug	Ethamivan [304-84-7]; Down 200; 18uM; PC3; HT_HG-U133A	CUL9 CEP152 IL17RC TMEM104 FBXO46	1.49e-05	194	37	5	7260_DN
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A	XYLT2 CUL9 CEP152 MMP16 INO80D	1.73e-05	200	37	5	5212_DN
Drug	hydroxyl radical	GNAS MMP15 MMP16 MMP17 SYNGAP1	1.99e-05	206	37	5	CID000157350
Drug	oxidized glutathione	MMP27 MMP20 MMP15 MMP16 MMP17	3.17e-05	227	37	5	CID000000975
Drug	noradrealine	MMP27 DGCR2 MMP20 MMP15 MMP16 MMP17 HAND2	3.37e-05	575	37	7	CID000000951
Drug	1q1g	MMP15 MMP16 NOTCH3	3.47e-05	39	37	3	CID000447992
Drug	latanoprost acid	MMP15 MMP16 MMP17	3.74e-05	40	37	3	CID006441636
Drug	AC1MPJID	MMP15 MMP16 PTPRN MMP17	3.84e-05	117	37	4	CID003386230
Drug	enantio-PAF-C16	MMP27 MMP20 MMP15 MMP16 MMP17	4.47e-05	244	37	5	CID000002499
Drug	1,10-phenanthroline	MMP27 MMP20 MMP15 MMP16 MMP17	6.85e-05	267	37	5	CID000001318
Drug	gluconate	MMP27 MMP20 MMP15 MMP16 MMP17	9.63e-05	287	37	5	CID000000604
Drug	NSC236997	MMP27 MMP20 MMP15 MMP16 PTPRN MMP17	2.13e-04	539	37	6	CID000005300
Drug	resveratrol; Up 200; 10uM; MCF7; HT_HG-U133A_EA	TMEM104 GNAS ROBO3 COQ8A	2.26e-04	185	37	4	841_UP
Drug	rapamycin, Streptomyces hygroscepicus; Up 200; 0.1uM; PC3; HT_HG-U133A	SERHL2 TTC39A MMP16 INO80D	2.40e-04	188	37	4	5980_UP
Drug	raloxifene	MMP27 MMP20 MMP15 MMP16 MMP17	2.46e-04	351	37	5	CID000005035
Drug	DB07883	MMP15 MMP16 MMP17	2.46e-04	75	37	3	CID000446476
Drug	dibutyryl cyclic 3',5'-AMP	MMP27 GNAS MMP20 MMP15 MMP16 MMP17	2.64e-04	561	37	6	CID000002460
Drug	U-62066 [87151-85-7]; Up 200; 1uM; MCF7; HT_HG-U133A	SERHL2 CEP152 TTC39A ROBO3	2.66e-04	193	37	4	3901_UP
Drug	UROX	DGCR2 PTPRN	2.66e-04	15	37	2	CID000008799
Drug	phenanthridinone; Down 200; 51.2uM; MCF7; HT_HG-U133A_EA	DGCR2 GNAS MMP16 NOTCH3	2.71e-04	194	37	4	1115_DN
Drug	5279552; Up 200; 22uM; MCF7; HT_HG-U133A_EA	CUL9 IL17RC COQ8A FBXO46	2.71e-04	194	37	4	843_UP
Drug	Spectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A	SERHL2 CUL9 GNAS MMP17	2.76e-04	195	37	4	3327_UP
Drug	Guaifenesin [93-14-1]; Up 200; 20.2uM; PC3; HT_HG-U133A	DGCR2 MMP15 GLI2 NOTCH3	2.76e-04	195	37	4	4549_UP
Drug	Cefoxitin sodium salt [33564-30-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A	DGCR2 CUL9 TMEM104 INO80D	2.76e-04	195	37	4	6796_DN
Drug	Sulfamerazine [127-79-7]; Down 200; 15.2uM; PC3; HT_HG-U133A	SERHL2 DGCR2 TTC39A NOTCH3	2.76e-04	195	37	4	3718_DN
Drug	Suxibuzone [27470-51-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A	SERHL2 DGCR2 GNAS MMP16	2.82e-04	196	37	4	6065_DN
Drug	Doxylamine succinate [562-10-7]; Down 200; 10.2uM; MCF7; HT_HG-U133A	DGCR2 CUL9 IL17RC BCR	2.82e-04	196	37	4	4819_DN
Drug	Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; HL60; HT_HG-U133A	XYLT2 DGCR2 TMEM104 GNAS	2.82e-04	196	37	4	2351_DN
Drug	Deferoxamine mesylate [138-14-7]; Down 200; 6uM; PC3; HT_HG-U133A	XYLT2 CEP152 INO80D GLI2	2.82e-04	196	37	4	3760_DN
Drug	estradiol; Up 200; 0.01uM; PC3; HT_HG-U133A	SERHL2 CEP152 GNAS TFR2	2.82e-04	196	37	4	5910_UP
Drug	Trimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; PC3; HT_HG-U133A	IL17RC TTC39A GLI2 NOTCH3	2.82e-04	196	37	4	4100_DN
Drug	Anabasine [494-52-0]; Up 200; 24.6uM; MCF7; HT_HG-U133A	SERHL2 MMP15 BCR MMP16	2.82e-04	196	37	4	6774_UP
Drug	Pilocarpine nitrate [148-72-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A	DGCR2 CEP152 MMP15 INO80D	2.82e-04	196	37	4	5341_UP
Drug	Diphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; MCF7; HT_HG-U133A	GNAS MMP15 MMP16 INO80D	2.82e-04	196	37	4	4416_DN
Drug	beta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; MCF7; HT_HG-U133A	XYLT2 TMEM104 ROBO3 MMP15	2.82e-04	196	37	4	4984_DN
Drug	Antazoline hydrochloride [2508-72-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A	DGCR2 CEP152 TMEM104 BCR	2.82e-04	196	37	4	6775_DN
Drug	Dimethisoquin hydrochloride [2773-92-4]; Down 200; 13uM; PC3; HT_HG-U133A	SERHL2 IL17RC GNAS NOTCH3	2.87e-04	197	37	4	4207_DN
Drug	Dropropizine (R,S) [17692-31-8]; Up 200; 17uM; PC3; HT_HG-U133A	XYLT2 TTC39A MMP16 INO80D	2.87e-04	197	37	4	5106_UP
Drug	Fenbufen [36330-85-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A	DGCR2 GNAS MMP16 MMP17	2.87e-04	197	37	4	3618_DN
Drug	Streptomycin sulfate [3810-74-0]; Up 200; 2.8uM; MCF7; HT_HG-U133A	SERHL2 CUL9 CEP152 MMP17	2.87e-04	197	37	4	3195_UP
Drug	Ioversol [87771-40-2]; Up 200; 5uM; HL60; HT_HG-U133A	ROBO3 MMP16 INO80D GLI2	2.87e-04	197	37	4	3026_UP
Drug	Aztreonam [78110-38-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A	CEP152 TMEM104 BCR MMP16	2.87e-04	197	37	4	2282_DN
Drug	Triprolidine hydrochloride [550-70-9]; Down 200; 12.8uM; PC3; HT_HG-U133A	PAN2 TMEM104 MMP16 FBXO46	2.87e-04	197	37	4	7248_DN
Drug	Phenindione [83-12-5]; Up 200; 18uM; PC3; HT_HG-U133A	SERHL2 BCR FBXO46 TFR2	2.87e-04	197	37	4	7289_UP
Drug	Carteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A	SERHL2 DGCR2 MMP15 INO80D	2.93e-04	198	37	4	3276_UP
Drug	Isoxicam [34552-84-6]; Down 200; 12uM; MCF7; HT_HG-U133A	XYLT2 DGCR2 COQ8A BCR	2.93e-04	198	37	4	7028_DN
Drug	16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A	SERHL2 DGCR2 BCR MMP16	2.93e-04	198	37	4	7505_DN
Drug	Streptomycin sulfate [3810-74-0]; Up 200; 2.8uM; PC3; HT_HG-U133A	XYLT2 BCR INO80D GLI2	2.93e-04	198	37	4	5837_UP
Drug	Methotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; MCF7; HT_HG-U133A	XYLT2 MMP15 FBXO46 NOTCH3	2.93e-04	198	37	4	3440_DN
Drug	Bemegride [64-65-3]; Down 200; 25.8uM; PC3; HT_HG-U133A	GNAS BCR INO80D NOTCH3	2.93e-04	198	37	4	6668_DN
Drug	Carbetapentane citrate [23142-01-0]; Down 200; 7.6uM; MCF7; HT_HG-U133A	XYLT2 IL17RC FBXO46 INO80D	2.93e-04	198	37	4	2623_DN
Drug	15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A	SERHL2 ROBO3 MMP17 GLI2	2.93e-04	198	37	4	7526_DN
Drug	Fosfosal [6064-83-1]; Up 200; 18.4uM; MCF7; HT_HG-U133A	SERHL2 CUL9 TTC39A INO80D	2.93e-04	198	37	4	3336_UP
Drug	Methimazole [60-56-0]; Up 200; 35uM; MCF7; HT_HG-U133A	CUL9 TTC39A ROBO3 INO80D	2.93e-04	198	37	4	3898_UP
Drug	Ethaverine hydrochloride [985-13-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A	SERHL2 CEP152 TMEM104 INO80D	2.98e-04	199	37	4	5337_UP
Drug	Bambuterol hydrochloride [81732-46-9]; Up 200; 10uM; HL60; HG-U133A	PAN2 DGCR2 TMEM104 GNAS	2.98e-04	199	37	4	1582_UP
Drug	Benoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A	TTC39A MMP20 MMP17 NOTCH3	2.98e-04	199	37	4	4115_UP
Drug	benserazide hydrochloride; Down 200; 10uM; MCF7; HG-U133A	GNAS MMP16 PTPRN INO80D	2.98e-04	199	37	4	641_DN
Drug	Thalidomide [50-35-1]; Up 200; 15.4uM; PC3; HT_HG-U133A	TMEM104 ROBO3 GLI2 NOTCH3	2.98e-04	199	37	4	2095_UP
Drug	rotenone; Down 200; 1uM; PC3; HT_HG-U133A	XYLT2 IL17RC TTC39A TFR2	2.98e-04	199	37	4	5920_DN
Drug	Cyclizine hydrochloride [303-25-3]; Up 200; 13.2uM; PC3; HT_HG-U133A	XYLT2 SERHL2 DGCR2 TTC39A	2.98e-04	199	37	4	5100_UP
Drug	Suxibuzone [27470-51-5]; Down 200; 9.2uM; HL60; HT_HG-U133A	XYLT2 DGCR2 INO80D TFR2	2.98e-04	199	37	4	2503_DN
Drug	Perhexiline maleate [6724-53-4]; Up 200; 10.2uM; PC3; HT_HG-U133A	DGCR2 TTC39A GLI2 TFR2	2.98e-04	199	37	4	5081_UP
Drug	Morantel tartrate [26155-31-7]; Down 200; 10.8uM; PC3; HT_HG-U133A	DGCR2 CUL9 IL17RC FBXO46	2.98e-04	199	37	4	7250_DN
Drug	Ia 4	GNAS PTPRN	3.04e-04	16	37	2	CID000032249
Drug	Amrinone [60719-84-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A	DGCR2 CEP152 TMEM104 FBXO46	3.04e-04	200	37	4	3465_DN
Drug	Fenoterol hydrobromide [1944-12-3]; Up 200; 10.4uM; MCF7; HT_HG-U133A	CEP152 IL17RC ROBO3 MMP16	3.04e-04	200	37	4	5432_UP
Drug	Spectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; HL60; HT_HG-U133A	SERHL2 ROBO3 MMP16 TFR2	3.04e-04	200	37	4	2987_UP
Drug	chlorpromazine hydrochloride; Down 200; 1uM; HL60; HT_HG-U133A	XYLT2 GNAS PIR TFR2	3.04e-04	200	37	4	2677_DN
Drug	Dicloxacillin sodium salt [13412-64-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A	DGCR2 CUL9 MMP15 INO80D	3.04e-04	200	37	4	5012_DN
Drug	Diphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; HL60; HG-U133A	DGCR2 CEP152 IL17RC INO80D	3.04e-04	200	37	4	1994_DN
Drug	peroxynitrite	MMP27 MMP20 MMP15 MMP16 MMP17	3.25e-04	373	37	5	CID000104806
Drug	Cabergoline-d5	DGCR2 GNAS TFR2	3.32e-04	83	37	3	CID000002512
Drug	AC1L2I7Q	DGCR2 PTPRN TFR2	3.32e-04	83	37	3	CID000072513
Drug	losartan	MMP27 MMP20 MMP15 MMP16 MMP17	3.46e-04	378	37	5	CID000003961
Drug	acetate	MMP27 MMP20 MMP15 MMP16 MMP17 HAND2	3.75e-04	599	37	6	CID000000175
Drug	aldosterone	MMP27 MMP20 MMP15 MMP16 MMP17	4.33e-04	397	37	5	CID000005839
Drug	aluminum citrate	BCR TFR2	4.79e-04	20	37	2	CID000091599
Disease	Mental Retardation, Psychosocial	SLC4A10 GNAS SYNGAP1	7.07e-04	139	37	3	C0025363
Disease	Profound Mental Retardation	SLC4A10 GNAS SYNGAP1	7.07e-04	139	37	3	C0020796
Disease	Mental deficiency	SLC4A10 GNAS SYNGAP1	7.07e-04	139	37	3	C0917816

Protein segments in the cluster

Peptide	Gene	Start	Entry
GPGPHSDHTLGTDLG	MAMDC4	96	Q6UXC1
HPVYHPEEGGDEGGS	CEP152	116	O94986
AFHGDADGSFGTPPG	BCR	421	P11274
SGTSQPHPGHGYLGE	ETV4	166	P43268
HAFPPGPGLGGDTHF	MMP27	181	Q9H306
GSHGGHATSFFGPAL	PAN2	91	Q504Q3
GIFGDHPGHSYGDLP	PTPRN	251	Q16849
YGSSHSPRHGGSFPG	MPLKIP	61	Q8TAP9
PHQGFMPGAHVFSGG	NUDT19	51	A8MXV4
HAYFPGPGLGGDTHF	MMP15	221	P51511
GGGAEPDHGPAHSEN	FBXO46	41	Q6PJ61
GGFPDHPHRGFETVS	PIR	51	O00625
GHGEEYPAAGAHSSP	NOTCH3	2216	Q9UM47
SDGPTYGHGHAGAAP	GLI2	941	P10070
GAAGLDHSHYGGVPP	HAND2	71	P61296
NFGGPEGEFHFSVPH	COQ8A	71	Q8NI60
SDDGEGGTFHFHDPP	DGCR2	416	P98153
GERAFPGQFHGLHDG	INO80D	776	Q53TQ3
GPLTLHEGQDFPHGG	CUL9	1816	Q8IWT3
FGGHGLSSHYSPGVP	SERHL2	66	Q9H4I8
DGVSGPGAHGPHDAF	IL17RC	666	Q8NAC3
HAFAPGEGLGGDTHF	MMP20	191	O60882
FGGHGLSSHYSPGVP	SERHL	66	Q9NQF3
PHGDYRGGEGPGHDF	RBM6	81	P78332
DGPGGTVAHAFFPGH	MMP17	201	Q9ULZ9
PGFPSGVHAGLEAFG	GNAS	121	Q5JWF2
SMGGAYHSPGFPGHV	ZC3H6	546	P61129
FPGPGIGGDTHFDSD	MMP16	211	P51512
HRGGEPPGDTFAPFH	SYNGAP1	966	Q96PV0
TFHGGFPQHPSGDLG	ROBO3	1031	Q96MS0
PNGTAAHGEAEPHGG	SLC4A10	456	Q6U841
IGHGQGEGHPPLADF	TMEM104	256	Q8NE00
GEGEGPSSHPLGFHF	ZNF316	586	A6NFI3
HPHFEGGVKLGVGAF	TTC39A	216	Q5SRH9
GHVHLGTGDPYTPGF	TFR2	321	Q9UP52
AGFPPHGDTGSVEGA	XYLT2	136	Q9H1B5
HGNFDFPHGNPGGTS	ZMIZ1	896	Q9ULJ6