Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhemi-methylated DNA-binding

WT1 EGR1

2.86e-063202GO:0044729
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

FOXH1 WT1 PER1 EGR1 NFE2 TP63 TP73 ZNF575

1.66e-051271208GO:0000987
GeneOntologyMolecularFunctiondouble-stranded methylated DNA binding

WT1 EGR1

2.00e-057202GO:0010385
GeneOntologyMolecularFunctionMDM2/MDM4 family protein binding

TP63 TP73

7.39e-0513202GO:0097371
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

WT1 PER1 EGR1 NFE2 TP63 TP73 ZNF575

1.35e-041244207GO:0000978
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

FOXH1 WT1 EGR1 TP63 TP73

1.86e-04560205GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

FOXH1 WT1 EGR1 TP63 TP73

1.96e-04566205GO:0001216
GeneOntologyMolecularFunctionWW domain binding

NFE2 TP63

2.82e-0425202GO:0050699
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

FOXH1 WT1 EGR1 NFE2 TP63 TP73 ZNF575

2.97e-041412207GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

WT1 PER1 EGR1 NFE2 TP63 TP73 ZNF575

3.64e-041459207GO:0000977
GeneOntologyMolecularFunctiontranscription factor binding

FOXH1 DCAF1 PER1 BTAF1 TP73

7.28e-04753205GO:0008134
GeneOntologyMolecularFunctiontranscription corepressor binding

PER1 TP73

1.58e-0359202GO:0001222
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

FOXH1 DCAF1 PER1 TP73

2.39e-03582204GO:0140297
GeneOntologyMolecularFunctionp53 binding

TP63 TP73

2.67e-0377202GO:0002039
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

EGR1 TP63

3.09e-0383202GO:1990841
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

FOXH1 DCAF1 TP73

7.92e-03417203GO:0061629
GeneOntologyMolecularFunctiontranscription coregulator binding

PER1 TP73

8.54e-03140202GO:0001221
GeneOntologyMolecularFunctionprotein domain specific binding

FOXH1 WT1 NFE2 TP63

1.01e-02875204GO:0019904
GeneOntologyBiologicalProcessregulation of metanephric glomerular mesangial cell proliferation

WT1 EGR1

8.93e-072202GO:0072301
GeneOntologyBiologicalProcesschromatin remodeling

DCAF1 WT1 PER1 EGR1 NFE2 TP63 BTAF1

3.87e-06741207GO:0006338
GeneOntologyBiologicalProcessmetanephric glomerular mesangium development

WT1 EGR1

5.35e-064202GO:0072223
GeneOntologyBiologicalProcessmetanephric glomerular mesangial cell proliferation involved in metanephros development

WT1 EGR1

5.35e-064202GO:0072262
GeneOntologyBiologicalProcessnegative regulation of intracellular steroid hormone receptor signaling pathway

FOXH1 PER1 TP63

7.53e-0640203GO:0033144
GeneOntologyBiologicalProcessnuclear receptor-mediated steroid hormone signaling pathway

FOXH1 PER1 EGLN2 TP63

8.07e-06136204GO:0030518
GeneOntologyBiologicalProcesschromatin organization

DCAF1 WT1 PER1 EGR1 NFE2 TP63 BTAF1

1.34e-05896207GO:0006325
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

FOXH1 PER1 EGLN2 TP63

1.35e-05155204GO:0043401
GeneOntologyBiologicalProcessestrogen receptor signaling pathway

FOXH1 EGLN2 TP63

2.21e-0557203GO:0030520
GeneOntologyBiologicalProcessmetanephric glomerulus vasculature development

WT1 EGR1

2.49e-058202GO:0072239
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

FOXH1 DCAF1 WT1 PER1 EGR1 DEDD TP63 BTAF1

2.65e-051399208GO:0045892
GeneOntologyBiologicalProcessprotein-DNA complex organization

DCAF1 WT1 PER1 EGR1 NFE2 TP63 BTAF1

2.72e-05999207GO:0071824
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

FOXH1 DCAF1 WT1 PER1 EGR1 DEDD TP63 BTAF1

2.84e-051413208GO:1902679
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

FOXH1 PER1 EGLN2 TP63

3.83e-05202204GO:0141193
GeneOntologyBiologicalProcesscell proliferation involved in metanephros development

WT1 EGR1

4.89e-0511202GO:0072203
GeneOntologyBiologicalProcessanimal organ formation

FOXH1 WT1 TP63

5.66e-0578203GO:0048645
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

FOXH1 PER1 EGLN2 TP63

7.36e-05239204GO:0071383
GeneOntologyBiologicalProcessregulation of intracellular steroid hormone receptor signaling pathway

FOXH1 PER1 TP63

7.85e-0587203GO:0033143
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

FOXH1 PER1 EGLN2 TP63

7.98e-05244204GO:0009755
GeneOntologyBiologicalProcessregulation of glomerular mesangial cell proliferation

WT1 EGR1

8.07e-0514202GO:0072124
GeneOntologyBiologicalProcessglomerular mesangial cell proliferation

WT1 EGR1

9.31e-0515202GO:0072110
GeneOntologyBiologicalProcessnegative regulation of intracellular estrogen receptor signaling pathway

FOXH1 TP63

9.31e-0515202GO:0033147
GeneOntologyBiologicalProcessmetanephric glomerulus development

WT1 EGR1

9.31e-0515202GO:0072224
GeneOntologyBiologicalProcessmetanephros development

WT1 EGR1 FRAS1

1.02e-0495203GO:0001656
GeneOntologyBiologicalProcessglomerular mesangium development

WT1 EGR1

1.35e-0418202GO:0072109
GeneOntologyBiologicalProcessregulation of cell proliferation involved in kidney development

WT1 EGR1

1.35e-0418202GO:1901722
GeneOntologyBiologicalProcesscellular response to organic cyclic compound

FOXH1 PER1 EGR1 EGLN2 TP63

2.30e-04605205GO:0071407
GeneOntologyBiologicalProcesscell proliferation involved in kidney development

WT1 EGR1

2.64e-0425202GO:0072111
GeneOntologyBiologicalProcessresponse to hormone

FOXH1 WT1 PER1 EGR1 EGLN2 TP63

3.44e-041042206GO:0009725
GeneOntologyBiologicalProcessmetanephros morphogenesis

WT1 FRAS1

3.57e-0429202GO:0003338
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

FOXH1 DCAF1 WT1 PER1 EGR1 TP63

3.65e-041053206GO:0000122
GeneOntologyBiologicalProcessglomerulus vasculature development

WT1 EGR1

3.82e-0430202GO:0072012
GeneOntologyBiologicalProcesskidney development

WT1 EGR1 FRAS1 TP73

4.01e-04372204GO:0001822
GeneOntologyBiologicalProcesskidney vasculature development

WT1 EGR1

4.08e-0431202GO:0061440
GeneOntologyBiologicalProcessrenal system vasculature development

WT1 EGR1

4.08e-0431202GO:0061437
GeneOntologyBiologicalProcessresponse to steroid hormone

FOXH1 PER1 EGLN2 TP63

4.39e-04381204GO:0048545
GeneOntologyBiologicalProcessrenal system development

WT1 EGR1 FRAS1 TP73

4.61e-04386204GO:0072001
GeneOntologyBiologicalProcesscellular response to hormone stimulus

FOXH1 WT1 PER1 EGLN2 TP63

5.35e-04727205GO:0032870
GeneOntologyBiologicalProcessregulation of intracellular estrogen receptor signaling pathway

FOXH1 TP63

5.52e-0436202GO:0033146
GeneOntologyBiologicalProcessneuron apoptotic process

EGR1 EGLN2 TP63 TP73

5.95e-04413204GO:0051402
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

FOXH1 PER1 EGLN2 TP63

6.12e-04416204GO:0030522
GeneOntologyBiologicalProcessmetanephric nephron development

WT1 EGR1

6.15e-0438202GO:0072210
GeneOntologyBiologicalProcessintrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

TP63 TP73

1.02e-0349202GO:0042771
GeneOntologyBiologicalProcessgenitalia development

WT1 TP63

1.24e-0354202GO:0048806
GeneOntologyBiologicalProcessdigestive tract morphogenesis

TP63 TP73

1.48e-0359202GO:0048546
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

FOXH1 WT1 PER1 EGR1 TP63 TP73

1.58e-031390206GO:0045944
GeneOntologyBiologicalProcesspositive regulation of miRNA transcription

WT1 EGR1

1.58e-0361202GO:1902895
GeneOntologyBiologicalProcessmuscle tissue development

FOXH1 WT1 EGR1 TP73

1.82e-03558204GO:0060537
GeneOntologyBiologicalProcesspositive regulation of miRNA metabolic process

WT1 EGR1

2.25e-0373202GO:2000630
GeneOntologyBiologicalProcesscircadian regulation of gene expression

PER1 EGR1

2.38e-0375202GO:0032922
GeneOntologyBiologicalProcessglomerulus development

WT1 EGR1

2.50e-0377202GO:0032835
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

FOXH1 WT1 FRAS1 TP63

2.65e-03619204GO:0002009
GeneOntologyBiologicalProcessresponse to organic cyclic compound

FOXH1 PER1 EGR1 EGLN2 TP63

2.74e-031048205GO:0014070
GeneOntologyBiologicalProcessregulation of miRNA transcription

WT1 EGR1

2.90e-0383202GO:1902893
GeneOntologyBiologicalProcessmiRNA transcription

WT1 EGR1

2.97e-0384202GO:0061614
GeneOntologyBiologicalProcessintrinsic apoptotic signaling pathway by p53 class mediator

TP63 TP73

3.62e-0393202GO:0072332
GeneOntologyBiologicalProcesscardiac muscle tissue development

FOXH1 WT1 TP73

3.68e-03327203GO:0048738
GeneOntologyBiologicalProcessstriated muscle tissue development

FOXH1 WT1 TP73

4.42e-03349203GO:0014706
GeneOntologyBiologicalProcessregulation of miRNA metabolic process

WT1 EGR1

4.42e-03103202GO:2000628
GeneOntologyBiologicalProcesspositive regulation of apoptotic process

WT1 EGR1 TP63 TP73

4.52e-03718204GO:0043065
HumanPhenoSeptate vagina

WT1 TP63

7.59e-051262HP:0001153
HumanPhenoEctopic anus

FOXH1 FRAS1 TP63

1.13e-049363HP:0004397
HumanPhenoAbnormal clitoris morphology

WT1 FRAS1 TP63

1.41e-0410063HP:0000056
HumanPhenoVaginal atresia

WT1 FRAS1

1.75e-041862HP:0000148
HumanPhenoGenital tract atresia

WT1 FRAS1

1.75e-041862HP:0001827
HumanPhenoCentral diabetes insipidus

FOXH1 TP63

2.64e-042262HP:0000863
HumanPhenoAmbiguous genitalia

FOXH1 WT1 FRAS1

2.67e-0412463HP:0000062
HumanPhenoAbnormal vagina morphology

WT1 FRAS1 TP63

2.93e-0412863HP:0000142
HumanPhenoUrethral atresia

FRAS1 TP63

3.15e-042462HP:0000068
HumanPhenoUrinary tract atresia

FRAS1 TP63

3.15e-042462HP:0000809
HumanPhenoChoanal atresia or stenosis

FOXH1 FRAS1 TP63

3.36e-0413463HP:0000416
HumanPhenoAbnormal choanae morphology

FOXH1 FRAS1 TP63

3.36e-0413463HP:0000415
HumanPhenoAbnormal cortical gyration

FOXH1 WT1 FRAS1 TP73

4.39e-0438864HP:0002536
HumanPhenoHypoplasia of penis

FOXH1 WT1 FRAS1 TP63

5.34e-0440864HP:0008736
HumanPhenoAbnormal female external genitalia morphology

WT1 FRAS1 TP63

5.78e-0416163HP:0000055
HumanPhenoAbsent eyelashes

FRAS1 TP63

6.01e-043362HP:0000561
HumanPhenoAnal stenosis

FRAS1 TP63

6.38e-043462HP:0002025
HumanPhenoAbsent facial hair

FRAS1 TP63

7.98e-043862HP:0002550
HumanPhenoStreak ovary

WT1 TP63

8.40e-043962HP:0010464
HumanPhenoCleft upper lip

FOXH1 FRAS1 TP63

8.42e-0418363HP:0000204
HumanPhenoAbnormality of neuronal migration

FOXH1 WT1 FRAS1 TP73

9.77e-0447764HP:0002269
HumanPhenoHeterotopias/abnormal migration

FOXH1 WT1 FRAS1 TP73

9.77e-0447764HP:0007317
HumanPhenoAniridia

WT1 TP63

1.12e-034562HP:0000526
HumanPhenoSparse axillary hair

WT1 TP63

1.17e-034662HP:0002215
HumanPhenoAbnormal lung lobation

WT1 FRAS1

1.22e-034762HP:0002101
HumanPhenoCorneal erosion

WT1 TP63

1.27e-034862HP:0200020
HumanPhenoHypoplastic male external genitalia

FOXH1 WT1 FRAS1 TP63

1.30e-0351464HP:0000050
HumanPhenoAbnormal lacrimal duct morphology

FRAS1 TP63

1.38e-035062HP:0011481
HumanPhenoSparse pubic hair

WT1 TP63

1.44e-035162HP:0002225
HumanPhenoBicornuate uterus

WT1 FRAS1

1.49e-035262HP:0000813
HumanPhenoAbnormal anus morphology

FOXH1 FRAS1 TP63

1.52e-0322463HP:0034915
HumanPhenoDecreased serum estradiol

WT1 TP63

1.61e-035462HP:0008214
HumanPhenoExternal genital hypoplasia

FOXH1 WT1 FRAS1 TP63

1.62e-0354464HP:0003241
HumanPhenoAbnormal posterior pituitary morphogenesis

FOXH1 TP63

1.67e-035562HP:0011751
HumanPhenoElevated circulating follicle stimulating hormone level

WT1 TP63

1.67e-035562HP:0008232
HumanPhenoAbnormality of the axillary hair

WT1 TP63

1.73e-035662HP:0100134
HumanPhenoAbnormality of the pubic hair

WT1 TP63

1.79e-035762HP:0100133
HumanPhenoAtresia of the external auditory canal

FRAS1 TP63

1.86e-035862HP:0000413
HumanPhenoAbnormal thymus morphology

FRAS1 TP63

1.86e-035862HP:0000777
HumanPhenoCleft lip

FOXH1 FRAS1 TP63

1.86e-0324063HP:0410030
HumanPhenoAbnormality of the anus

FOXH1 FRAS1 TP63

2.00e-0324663HP:0004378
HumanPhenoAbsent hair

FRAS1 TP63

2.05e-036162HP:0002298
HumanPhenoAbnormal serum estradiol

WT1 TP63

2.12e-036262HP:0025133
HumanPhenoAbnormal circulating estrogen level

WT1 TP63

2.19e-036362HP:0025132
HumanPhenoAbnormal number of incisors

FOXH1 TP63

2.19e-036362HP:0011064
HumanPhenoAbnormality of the uterus

WT1 FRAS1 TP63

2.24e-0325663HP:0000130
HumanPhenoDiabetes insipidus

FOXH1 TP63

2.26e-036462HP:0000873
HumanPhenoAnteriorly placed anus

FOXH1 TP63

2.54e-036862HP:0001545
HumanPhenoRenal duplication

WT1 TP63

2.62e-036962HP:0000075
HumanPhenoAbdominal organ duplication

WT1 TP63

2.62e-036962HP:0005217
HumanPhenoClitoral hypertrophy

WT1 FRAS1

2.69e-037062HP:0008665
HumanPhenoAbnormal size of the clitoris

WT1 FRAS1

2.69e-037062HP:0040252
HumanPhenoIncreased size of the clitoris

WT1 FRAS1

2.69e-037062HP:0040253
MousePhenoabnormal lung morphology

FOXH1 WT1 EGR1 DEDD FRAS1 TP63 TP73

6.36e-06767157MP:0001175
MousePhenoincreased hemolymphoid system tumor incidence

EGR1 NFE2 TP63 TP73

4.10e-05191154MP:0010296
MousePhenoabnormal respiratory system morphology

FOXH1 WT1 EGR1 DEDD FRAS1 TP63 TP73

4.31e-051027157MP:0002132
MousePhenoabsent eyelids

FRAS1 TP63

7.05e-0512152MP:0001341
MousePhenoabsent ovary

WT1 TP63

8.33e-0513152MP:0003578
MousePhenomyocardium hypoplasia

FOXH1 WT1 BTAF1

9.70e-0586153MP:0010500
MousePhenoincreased metanephric mesenchyme apoptosis

WT1 FRAS1

9.71e-0514152MP:0011386
MousePhenoabnormal ovulation

WT1 EGR1 TP73

1.39e-0497153MP:0001928
MousePhenoabnormal blood circulation

WT1 NFE2 FRAS1 TP63 BTAF1 TP73

1.50e-04845156MP:0002128
MousePhenoincreased sarcoma incidence

NFE2 TP63 TP73

1.61e-04102153MP:0002032
MousePhenoagonadal

WT1 TP63

1.63e-0418152MP:0005644
MousePhenoabsent sex gland

WT1 TP63

1.63e-0418152MP:0000654
MousePhenoheart hypoplasia

FOXH1 WT1 BTAF1

1.66e-04103153MP:0002740
MousePhenoabnormal skin development

FRAS1 TP63

1.82e-0419152MP:0003941
MousePhenoabnormal metanephros morphology

WT1 FRAS1

2.23e-0421152MP:0011364
MousePhenothick dermal layer

EGR1 TP63

2.45e-0422152MP:0001245
MousePhenoblistering

FRAS1 TP63

2.93e-0424152MP:0001208
MousePhenosmall heart

FOXH1 WT1 DEDD BTAF1

3.05e-04321154MP:0002188
MousePhenoabnormal metanephric mesenchyme morphology

WT1 FRAS1

3.18e-0425152MP:0010984
MousePhenoabnormal glomerular capsule space morphology

WT1 FRAS1

3.71e-0427152MP:0011499
MousePhenoabnormal kidney mesenchyme morphology

WT1 FRAS1

4.00e-0428152MP:0010985
MousePhenoabsent spleen

FOXH1 WT1

4.29e-0429152MP:0000690
MousePhenodiaphragmatic hernia

FOXH1 WT1

4.29e-0429152MP:0003924
MousePhenohemorrhage

WT1 NFE2 FRAS1 TP63 TP73

4.80e-04664155MP:0001914
MousePhenoincreased lung adenoma incidence

TP63 TP73

5.57e-0433152MP:0002048
MousePhenoanovulation

EGR1 TP73

5.57e-0433152MP:0008869
MousePhenoabnormal lung adenoma incidence

TP63 TP73

5.57e-0433152MP:0020190
MousePhenoincreased classified tumor incidence

EGR1 NFE2 TP63 TP73

5.84e-04381154MP:0010273
MousePhenoabnormal classified tumor incidence

EGR1 NFE2 TP63 TP73

6.02e-04384154MP:0020188
MousePhenointernal hemorrhage

WT1 NFE2 FRAS1 TP73

6.20e-04387154MP:0001634
MousePhenoincreased lymphoma incidence

EGR1 TP63 TP73

6.50e-04164153MP:0012431
MousePhenoincreased organ/body region tumor incidence

EGR1 NFE2 TP63 TP73

6.69e-04395154MP:0010274
MousePhenoabnormal organ/body region tumor incidence

EGR1 NFE2 TP63 TP73

7.08e-04401154MP:0013152
MousePhenoincreased osteoblast cell number

PER1 NFE2

7.39e-0438152MP:0004988
MousePhenoincreased incidence of induced tumors

EGR1 NFE2 TP73

7.60e-04173153MP:0002021
MousePhenokidney cyst

WT1 FRAS1 TP63

8.12e-04177153MP:0003675
MousePhenoabsent estrous cycle

PER1 EGR1

9.91e-0444152MP:0009009
MousePhenoabnormal ovary morphology

WT1 EGR1 TP63 TP73

1.10e-03451154MP:0001126
MousePhenoabnormal glomerular capillary morphology

WT1 FRAS1

1.13e-0347152MP:0011320
MousePhenoabnormal kidney capillary morphology

WT1 FRAS1

1.18e-0348152MP:0011310
MousePhenoabnormal cranium morphology

FOXH1 NFE2 FRAS1 TP63 TP73

1.21e-03813155MP:0000438
MousePhenoabnormal fluid regulation

FOXH1 WT1 TP63 BTAF1 TP73

1.30e-03826155MP:0001784
MousePhenoabnormal craniofacial bone morphology

FOXH1 NFE2 FRAS1 TP63 TP73

1.31e-03827155MP:0002116
MousePhenoabnormal female reproductive gland morphology

WT1 EGR1 TP63 TP73

1.33e-03475154MP:0013324
MousePhenoincreased T cell derived lymphoma incidence

EGR1 TP73

1.43e-0353152MP:0002024
MousePhenodecreased aggression

EGR1 TP73

1.43e-0353152MP:0005656
MousePhenoincreased thymus tumor incidence

EGR1 TP73

1.49e-0354152MP:0010365
MousePhenoabnormal female reproductive system physiology

WT1 PER1 EGR1 TP63 TP73

1.69e-03876155MP:0003699
MousePhenomyocardial trabeculae hypoplasia

FOXH1 BTAF1

1.72e-0358152MP:0010503
MousePhenoincreased malignant tumor incidence

NFE2 TP63 TP73

1.88e-03237153MP:0002018
MousePhenoabnormal head development

FOXH1 BTAF1

1.96e-0362152MP:0012176
MousePhenoincreased tumor incidence

EGR1 NFE2 TP63 TP73

2.00e-03530154MP:0002020
MousePhenoabnormal ovarian follicle morphology

WT1 EGR1 TP73

2.07e-03245153MP:0001131
MousePhenoabnormal superovulation

WT1 TP73

2.22e-0366152MP:0009648
MousePhenoglomerulosclerosis

WT1 FRAS1

2.35e-0368152MP:0005264
MousePhenoabnormal incidence of induced tumors

EGR1 NFE2 TP73

2.70e-03269153MP:0013151
MousePhenoabnormal prostate gland morphology

EGR1 TP63

2.70e-0373152MP:0001158
MousePhenoabnormal kidney vasculature morphology

WT1 FRAS1

2.70e-0373152MP:0000530
MousePhenopremature aging

PER1 TP63

2.70e-0373152MP:0003786
MousePhenoedema

FOXH1 WT1 BTAF1 TP73

2.79e-03581154MP:0001785
MousePhenoabnormal osteoblast cell number

PER1 NFE2

3.00e-0377152MP:0004987
MousePhenoincreased osteoclast cell number

EGR1 NFE2

3.00e-0377152MP:0004984
MousePhenoabnormal diaphragm morphology

FOXH1 WT1

3.08e-0378152MP:0002279
MousePhenoincreased apoptosis

DCAF1 WT1 FRAS1 TP63 TP73

3.15e-031008155MP:0006042
DomainP53

TP63 TP73

2.63e-063182PF00870
DomainP53_tetramer

TP63 TP73

2.63e-063182PF07710
Domainp53_DNA-bd

TP63 TP73

2.63e-063182IPR011615
DomainP53

TP63 TP73

2.63e-063182PS00348
Domain-

TP63 TP73

2.63e-0631824.10.170.10
Domainp53_tumour_suppressor

TP63 TP73

2.63e-063182IPR002117
Domainp53_tetrameristn

TP63 TP73

2.63e-063182IPR010991
Domainp53/RUNT-type_TF_DNA-bd

TP63 TP73

1.31e-056182IPR012346
Domain-

TP63 TP73

1.31e-0561822.60.40.720
DomainSAM_2

TP63 TP73

7.74e-0443182PF07647
Domainp53-like_TF_DNA-bd

TP63 TP73

1.17e-0353182IPR008967
DomainSAM

TP63 TP73

3.20e-0388182SM00454
DomainSAM_DOMAIN

TP63 TP73

3.71e-0395182PS50105
DomainSAM

TP63 TP73

3.87e-0397182IPR001660
Domain-

TP63 TP73

4.60e-031061821.10.150.50
DomainSAM/pointed

TP63 TP73

5.58e-03117182IPR013761
Domain-

DCAF1 BTAF1

1.90e-022221821.25.10.10
PathwayPID_P73PATHWAY

WT1 DEDD TP63 TP73

1.19e-0679154M19
PathwayREACTOME_ACTIVATION_OF_PUMA_AND_TRANSLOCATION_TO_MITOCHONDRIA

TP63 TP73

3.79e-059152M26946
PathwayREACTOME_TP53_REGULATES_TRANSCRIPTION_OF_DEATH_RECEPTORS_AND_LIGANDS

TP63 TP73

6.93e-0512152M27631
PathwayREACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CASPASE_ACTIVATORS_AND_CASPASES

TP63 TP73

6.93e-0512152M27630
PathwayREACTOME_TP53_REGULATES_TRANSCRIPTION_OF_SEVERAL_ADDITIONAL_CELL_DEATH_GENES_WHOSE_SPECIFIC_ROLES_IN_P53_DEPENDENT_APOPTOSIS_REMAIN_UNCERTAIN

TP63 TP73

9.55e-0514152M27629
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS

TP63 TP73

9.55e-0514152MM15341
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS

TP63 TP73

9.55e-0514152M27638
PathwayWP_TP53_NETWORK

TP63 TP73

1.79e-0419152M39368
PathwayREACTOME_TP53_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_CYTOCHROME_C_RELEASE

TP63 TP73

1.99e-0420152M27628
PathwayREACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS

TP63 TP73

4.52e-0430152M17814
PathwayREACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_DEATH_GENES

TP63 TP73

9.74e-0444152M27499
PathwayREACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS

TP63 TP73

1.52e-0355152M7455
PathwayWP_MARKERS_OF_KIDNEY_CELL_LINEAGE

WT1 EGLN2

1.75e-0359152M46460
PathwayWP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM

WT1 FRAS1

1.81e-0360152M40048
Pubmed

Physical interaction between Wilms tumor 1 and p73 proteins modulates their functions.

WT1 TP63 TP73

7.59e-10421310744705
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

FOXH1 WT1 PER1 EGR1 DEDD NFE2 TP63 TP73

2.41e-0887721820211142
Pubmed

p63 and p73 expression in extrahepatic bile duct carcinoma and their clinical significance.

TP63 TP73

3.47e-07221217385050
Pubmed

p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis.

TP63 TP73

3.47e-07221216413471
Pubmed

The role of p53 protein family in gastrointestinal malignancies.

TP63 TP73

3.47e-07221216557273
Pubmed

Tumor-specific p73 up-regulation mediates p63 dependence in squamous cell carcinoma.

TP63 TP73

3.47e-07221217018588
Pubmed

The 5th International p63/p73 Workshop: much more than just tumour suppression.

TP63 TP73

3.47e-07221222240899
Pubmed

Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization.

TP63 TP73

3.47e-07221227716744
Pubmed

Conformational stability and activity of p73 require a second helix in the tetramerization domain.

TP63 TP73

3.47e-07221219763140
Pubmed

Polymorphisms in the p63 and p73 genes are associated with ovarian cancer risk and clinicopathological variables.

TP63 TP73

3.47e-07221223095717
Pubmed

p73 and p63 regulate the expression of fibroblast growth factor receptor 3.

TP63 TP73

3.47e-07221220298673
Pubmed

EGR1 regulates hepatic clock gene amplitude by activating Per1 transcription.

PER1 EGR1

3.47e-07221226471974
Pubmed

Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence.

WT1 EGR1

3.47e-07221225258363
Pubmed

Wilms' tumor gene 1 regulates p63 and promotes cell proliferation in squamous cell carcinoma of the head and neck.

WT1 TP63

3.47e-07221225929687
Pubmed

Characterization of the zinc finger protein encoded by the WT1 Wilms' tumor locus.

WT1 EGR1

3.47e-0722121662794
Pubmed

P634A4 and TAp73 immunocytochemistry in liquid-based cervical cytology--potential biomarkers for diagnosis and progress prediction of cervical neoplasia.

TP63 TP73

3.47e-07221220081800
Pubmed

Induction of mPer1 expression by GnRH in pituitary gonadotrope cells involves EGR-1.

PER1 EGR1

3.47e-07221219616057
Pubmed

Distinct p63 and p73 Protein Interactions Predict Specific Functions in mRNA Splicing and Polyploidy Control in Epithelia.

TP63 TP73

3.47e-07221233375680
Pubmed

p63 and p73: roles in development and tumor formation.

TP63 TP73

3.47e-07221215280445
Pubmed

p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53.

TP63 TP73

3.47e-07221210373484
Pubmed

p63 and p73 do not contribute to p53-mediated lymphoma suppressor activity in vivo.

TP63 TP73

3.47e-07221216007185
Pubmed

TP63 and TP73 in cancer, an unresolved "family" puzzle of complexity, redundancy and hierarchy.

TP63 TP73

3.47e-07221224983500
Pubmed

Transient and recurrent expression of the Egr-1 gene in epithelial and mesenchymal cells during tooth morphogenesis suggests involvement in tissue interactions and in determination of cell fate.

WT1 EGR1

3.47e-0722121489725
Pubmed

In situ expression of the early growth response gene-1 during murine nephrogenesis.

WT1 EGR1

3.47e-0722127609158
Pubmed

The Role of p63 and p73 in tumor formation and progression: coming of age toward clinical usefulness. Commentary re: F. Koga et al., Impaired p63 expression associates with poor prognosis and uroplakin III expression in invasive urothelial carcinoma of the bladder. Clin. Cancer Res., 9: 5501-5507, 2003, and P. Puig et al., p73 Expression in human normal and tumor tissues: loss of p73alpha expression is associated with tumor progression in bladder Cancer. Clin. Cancer Res., 9: 5642-5651, 2003.

TP63 TP73

3.47e-07221214654522
Pubmed

Role of p63 and p73 isoforms on the cell death in patients with hepatocellular carcinoma submitted to orthotopic liver transplantation.

TP63 TP73

3.47e-07221228350813
Pubmed

Genome-wide mapping indicates that p73 and p63 co-occupy target sites and have similar dna-binding profiles in vivo.

TP63 TP73

3.47e-07221220644729
Pubmed

The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers.

TP63 TP73

3.47e-07221217446929
Pubmed

Tissue-specific expression of p73 and p63 isoforms in human tissues.

TP63 TP73

3.47e-07221234315849
Pubmed

p63 antagonizes p53 to promote the survival of embryonic neural precursor cells.

TP63 TP73

3.47e-07221219458240
Pubmed

While p73 is essential, p63 is completely dispensable for the development of the central nervous system.

TP63 TP73

3.47e-07221221293190
Pubmed

Neuronal survival and p73/p63/p53: a family affair.

TP63 TP73

1.04e-06321215359011
Pubmed

The p53-family members p63 and p73 inhibit insulin-like growth factor-I receptor gene expression in colon cancer cells.

TP63 TP73

1.04e-06321216181796
Pubmed

Glyoxalase II, a detoxifying enzyme of glycolysis byproduct methylglyoxal and a target of p63 and p73, is a pro-survival factor of the p53 family.

TP63 TP73

1.04e-06321216831876
Pubmed

Evaluating the Influence of a G-Quadruplex Prone Sequence on the Transactivation Potential by Wild-Type and/or Mutant P53 Family Proteins through a Yeast-Based Functional Assay.

TP63 TP73

1.04e-06321233672023
Pubmed

p53 Family isoforms.

TP63 TP73

1.04e-06321218289041
Pubmed

The integrin alpha(v)beta(3-5) ligand MFG-E8 is a p63/p73 target gene in triple-negative breast cancers but exhibits suppressive functions in ER(+) and erbB2(+) breast cancers.

TP63 TP73

1.04e-06321221127199
Pubmed

Differential regulation of vitamin D receptor (VDR) by the p53 Family: p73-dependent induction of VDR upon DNA damage.

TP63 TP73

1.04e-06321217716971
Pubmed

Regulation and function of the p53-related proteins: same family, different rules.

TP63 TP73

1.04e-06321210754563
Pubmed

p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.

TP63 TP73

1.04e-06321216601753
Pubmed

Differential expression of p53 gene family members p63 and p73 in head and neck squamous tumorigenesis.

TP63 TP73

1.04e-06321211957139
Pubmed

iASPP inhibits p53-independent apoptosis by inhibiting transcriptional activity of p63/p73 on promoters of proapoptotic genes.

TP63 TP73

1.04e-06321222538442
Pubmed

The emerging p53 gene family.

TP63 TP73

1.04e-06321210203277
Pubmed

The tumor suppressors p53, p63, and p73 are regulators of microRNA processing complex.

TP63 TP73

1.04e-06321220485546
Pubmed

Melanocyte and keratinocyte carcinogenesis: p53 family protein activities and intersecting mRNA expression profiles.

TP63 TP73

1.04e-06321216363065
Pubmed

p63 and p73 coordinate p53 function to determine the balance between survival, cell death, and senescence in adult neural precursor cells.

TP63 TP73

1.04e-06321224809925
Pubmed

Crystal structures of the DNA-binding domain tetramer of the p53 tumor suppressor family member p73 bound to different full-site response elements.

TP63 TP73

1.04e-06321223243311
Pubmed

p53, p63 and p73--solos, alliances and feuds among family members.

TP63 TP73

1.04e-06321211825686
Pubmed

The dominant-negative interplay between p53, p63 and p73: A family affair.

TP63 TP73

1.04e-06321227589690
Pubmed

ΔNp63 regulates select routes of reprogramming via multiple mechanisms.

TP63 TP73

1.04e-06321224013722
Pubmed

The Wilms' tumour suppressor protein WT1 acts as a key transcriptional repressor of the human thromboxane A2 receptor gene in megakaryocytes.

WT1 EGR1

1.04e-06321219067769
Pubmed

Interaction between TP63 and MDM2 genes and the risk of recurrent pregnancy loss.

TP63 TP73

1.04e-06321225218545
Pubmed

The p53 family: guardians of maternal reproduction.

TP63 TP73

1.04e-06321221427767
Pubmed

Physical interaction with Yes-associated protein enhances p73 transcriptional activity.

TP63 TP73

1.04e-06321211278685
Pubmed

[Clinical significance of the expression of p53, p63 and p73 in nasal and paranasal sinus carcinoma].

TP63 TP73

1.04e-06321219119599
Pubmed

p63 and p73 are not required for the development and p53-dependent apoptosis of T cells.

TP63 TP73

1.04e-06321215261144
Pubmed

Expression of p53 family in scars.

TP63 TP73

1.04e-06321214757278
Pubmed

Diverse p63 and p73 isoforms regulate Δ133p53 expression through modulation of the internal TP53 promoter activity.

TP63 TP73

1.04e-06321222075982
Pubmed

Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family.

TP63 TP73

1.04e-06321215837625
Pubmed

Structural evolution of p53, p63, and p73: implication for heterotetramer formation.

TP63 TP73

1.04e-06321219815500
Pubmed

S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation.

TP63 TP73

1.04e-06321216449968
Pubmed

deltaEF1 repressor controls selectively p53 family members during differentiation.

TP63 TP73

1.04e-06321216007124
Pubmed

Repression of Pax-2 by WT1 during normal kidney development.

WT1 EGR1

1.04e-0632127720589
Pubmed

Expression of p53 family genes in urinary bladder cancer: correlation with disease aggressiveness and recurrence.

TP63 TP73

1.04e-06321224213852
Pubmed

Intrinsic aggregation propensity of the p63 and p73 TI domains correlates with p53R175H interaction and suggests further significance of aggregation events in the p53 family.

TP63 TP73

1.04e-06321227447112
Pubmed

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage.

TP63 TP73

1.04e-06321211932750
Pubmed

Tumor suppressors p53, p63TAα, p63TAy, p73α, and p73β use distinct pathways to repress telomerase expression.

TP63 TP73

1.04e-06321222496369
Pubmed

Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain.

TP63 TP73

1.04e-06321230099987
Pubmed

How the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: regulators and effectors.

TP63 TP73

1.04e-06321224488880
Pubmed

A novel response element confers p63- and p73-specific activation of the WNT4 promoter.

TP63 TP73

1.04e-06321216343436
Pubmed

Novel therapeutic interventions for p53-altered tumors through manipulation of its family members, p63 and p73.

TP63 TP73

1.04e-06321226652033
Pubmed

A network of p73, p53 and Egr1 is required for efficient apoptosis in tumor cells.

EGR1 TP73

1.04e-06321216990849
Pubmed

Differential expression of p53, p63 and p73 proteins in human buccal squamous-cell carcinomas.

TP63 TP73

1.04e-06321212969350
Pubmed

p63 and p73 repress CXCR5 chemokine receptor gene expression in p53-deficient MCF-7 breast cancer cells during genotoxic stress.

TP63 TP73

2.08e-06421229107083
Pubmed

Regulated expression of the alpha isoform of the human thromboxane A2 receptor during megakaryocyte differentiation: a coordinated role for WT1, Egr1, and Sp1.

WT1 EGR1

2.08e-06421219747485
Pubmed

A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain.

TP63 TP73

2.08e-06421211238924
Pubmed

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

TP63 TP73

2.08e-06421215607981
Pubmed

Mutant p53 antagonizes p63/p73-mediated tumor suppression via Notch1.

TP63 TP73

2.08e-06421231712410
Pubmed

Gene expression of cyclin-dependent kinase subunit Cks2 is repressed by the tumor suppressor p53 but not by the related proteins p63 or p73.

TP63 TP73

2.08e-06421217336302
Pubmed

Identification of Daxx interacting with p73, one of the p53 family, and its regulation of p53 activity by competitive interaction with PML.

TP63 TP73

2.08e-06421212954772
Pubmed

E3 ubiquitin ligase TRIM32 negatively regulates tumor suppressor p53 to promote tumorigenesis.

TP63 TP73

2.08e-06421225146927
Pubmed

Transient inhibition of p53 homologs protects ovarian function from two distinct apoptotic pathways triggered by anticancer therapies.

TP63 TP73

2.08e-06421229988075
Pubmed

p73 and p63 protein stability: the way to regulate function?

TP63 TP73

2.08e-06421214555234
Pubmed

ASPP1 and ASPP2: common activators of p53 family members.

TP63 TP73

2.08e-06421214729977
Pubmed

Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo.

TP63 TP73

2.08e-06421211925430
Pubmed

Functional interplay between MDM2, p63/p73 and mutant p53.

TP63 TP73

2.08e-06421225417702
Pubmed

TNF-α promotes c-REL/ΔNp63α interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer.

TP63 TP73

2.08e-06421221933882
Pubmed

IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo.

TP63 TP73

2.08e-06421225409149
Pubmed

Thymine-DNA glycosylase interacts with and functions as a coactivator of p53 family proteins.

TP63 TP73

2.08e-06421218951877
Pubmed

Utility of WT-1, p63, MOC31, mesothelin, and cytokeratin (K903 and CK5/6) immunostains in differentiating adenocarcinoma, squamous cell carcinoma, and malignant mesothelioma in effusions.

WT1 TP63

2.08e-06421218064689
Pubmed

The transcriptional repressor hDaxx potentiates p53-dependent apoptosis.

TP63 TP73

2.08e-06421215339933
Pubmed

The p53 family members have distinct roles during mammalian embryonic development.

TP63 TP73

2.08e-06421228211873
Pubmed

Interaction of regulators Mdm2 and Mdmx with transcription factors p53, p63 and p73.

TP63 TP73

3.47e-06521221088494
Pubmed

The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells.

TP63 TP73

3.47e-06521227889317
Pubmed

Molecular mechanism of mutant p53 stabilization: the role of HSP70 and MDM2.

TP63 TP73

3.47e-06521223251530
Pubmed

An anterograde pathway for sensory axon degeneration gated by a cytoplasmic action of the transcriptional regulator P53.

TP63 TP73

3.47e-06521233823136
Pubmed

p63 induces key target genes required for epidermal morphogenesis.

FRAS1 TP63

3.47e-06521217360634
Pubmed

p53 family members in myogenic differentiation and rhabdomyosarcoma development.

TP63 TP73

3.47e-06521217045206
Pubmed

Regulation of female reproduction by p53 and its family members.

TP63 TP73

3.47e-06521221402718
Pubmed

Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73.

TP63 TP73

3.47e-06521218275817
InteractionWT1 interactions

WT1 EGR1 TP63 TP73

1.06e-0676214int:WT1
InteractionWWP1 interactions

DCAF1 EGR1 NFE2 TP63 TP73

5.91e-06260215int:WWP1
InteractionNPIPB13 interactions

TP63 TP73

6.20e-064212int:NPIPB13
InteractionAGBL2 interactions

TP63 TP73

3.71e-059212int:AGBL2
InteractionMTHFSD interactions

TP63 TP73

4.63e-0510212int:MTHFSD
InteractionHIF1A interactions

PER1 EGLN2 TP63 BTAF1 TP73

7.47e-05441215int:HIF1A
InteractionPIWIL1 interactions

TP63 TP73

1.23e-0416212int:PIWIL1
InteractionWTIP interactions

WT1 EGLN2

1.23e-0416212int:WTIP
InteractionNEDD4 interactions

EGR1 NFE2 TP63 CAMKK2 TP73

2.00e-04544215int:NEDD4
InteractionTOPBP1 interactions

DCAF1 TP63 TP73

2.35e-04117213int:TOPBP1
InteractionHPSE2 interactions

DCAF1 FRAS1

3.06e-0425212int:HPSE2
InteractionCREBBP interactions

FOXH1 WT1 EGR1 NFE2 TP73

3.13e-04599215int:CREBBP
Cytoband22q11.21

PI4KAP1 PI4KAP2

1.18e-0311121222q11.21
CytobandEnsembl 112 genes in cytogenetic band chr22q11

PI4KAP1 PI4KAP2

1.56e-02419212chr22q11
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

WT1 EGR1 ZNF575

4.38e-037189328
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#1_top-relative-expression-ranked_100

EGR1 SHISA3

6.11e-0512212gudmap_developingKidney_e15.5_Cap mesenchyme_100_k1
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#1_top-relative-expression-ranked_100

EGR1 SHISA3

8.42e-0514212gudmap_developingKidney_e15.5_Peripheral blastema_100_k1
CoexpressionAtlasMesoderm Day 5-method_retro_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

WT1 EGR1 SHISA3

9.58e-0591213PCBC_ratio_MESO-5_from-retro_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

WT1 EGR1 SHISA3

9.58e-0591213PCBC_ratio_MESO-5_from-OSKM_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#1_top-relative-expression-ranked_500

WT1 EGR1 SHISA3

1.68e-04110213gudmap_developingKidney_e15.5_Podocyte cells_500_k1
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#5

FRAS1 TP63 SHISA3

1.87e-04114213Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000_K5
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#4_top-relative-expression-ranked_100

WT1 SHISA3

2.33e-0423212gudmap_developingKidney_e15.5_Podocyte cells_100_k4
CoexpressionAtlasDevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#4_top-relative-expression-ranked_1000

NFE2 BTAF1 SHISA3

3.01e-04134213gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000_k4
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#1_top-relative-expression-ranked_200

EGR1 SHISA3

3.22e-0427212gudmap_developingKidney_e15.5_Peripheral blastema_200_k1
CoexpressionAtlaskidney_P2_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_500

WT1 SHISA3

3.47e-0428212gudmap_kidney_P2_CapMes_Crym_k4_500
CoexpressionAtlaskidney_P1_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_500

WT1 SHISA3

4.26e-0431212gudmap_kidney_P1_CapMes_Crym_k3_500
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#4_top-relative-expression-ranked_200

EGR1 SHISA3

4.26e-0431212gudmap_developingKidney_e15.5_Cap mesenchyme_200_k4
ToppCell(00)_Basal-(4)_1wkpi|(00)_Basal / shred by cell type and Timepoint

PER1 EGR1 TP63 TP73

1.57e-06185214bf82ba905e5eee1c39a2731702071d3de10a78b8
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PER1 EGR1

4.77e-0522212e345c8c639ca1935b2e2c32533cc8e30819acfeb
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

EGR1 FRAS1 TP63

5.29e-051572136ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellwk_20-22-Epithelial-Airway_epithelial_progenitor-epi-stalk_late|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FOXH1 KIF12 TP63

6.25e-05166213b60954e5625743657d0fd9264b738b46e72fd8a6
ToppCellwk_20-22-Epithelial-Airway_epithelial_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FOXH1 KIF12 TP63

6.25e-05166213fcd0bd70b553789092249806ace324b77bd10481
ToppCellFetal_29-31_weeks-Epithelial-basal_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FRAS1 TP63 TP73

6.47e-051682136521bead9789d626b86cbd08692c621c5a5aef33
ToppCellFetal_29-31_weeks-Epithelial-basal_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FRAS1 TP63 TP73

6.59e-05169213c3ee781735a9288ce1822b230d39bb91c1415589
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 ZNF575 SHISA3

6.94e-05172213073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NFE2 EGLN2 TP63

7.31e-0517521343be63976da5ad0764d24d90919a77ce46068f52
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Neuronal-GABAergic_neurons|GW10 / Sample Type, Dataset, Time_group, and Cell type.

EGR1 TP63 ZNF575

7.31e-05175213d4ff1f197ad4086286e86817cbff24fa718293fc
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EGR1 FRAS1 TP63

7.56e-0517721375cb2067a3f2d1b5a964890b02b604d1e79bd163
ToppCellwk_08-11-Hematologic-Meg-ery-Cycling_definitive_erythroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FOXH1 NFE2 C17orf99

8.89e-05187213c0965293f08d3e49000871777a5b26d81a4af203
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Striatum / BrainAtlas - Mouse McCarroll V32

EGR1 FRAS1 CAMKK2

9.03e-05188213e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PER1 EGR1 BTAF1

9.76e-05193213dbf0fe496254320c894568c31e5f9ce63707d1b5
ToppCellBiopsy_Other_PF-Mesenchymal-Mesothelial_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

WT1 FRAS1 SHISA3

1.05e-0419821386736f01e61bf4961f060b24ee1f1f48340737dd
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 TP63 TP73

1.07e-0419921394a7867e800df352731796de8c24cba133c29622
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FOXH1 FRAS1 TP63

1.07e-04199213e9c47f565a0a7737ecff68569d668aeb707ae5a6
ToppCellInfluenza|World / Disease, condition lineage and cell class

PER1 EGR1 NFE2

1.08e-04200213df996c35907a1c9194b9e2ca30e81f520ca067f0
ToppCelldroplet-Tongue-nan-24m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMKK2 ZNF575

1.08e-03104212a4ae3cae44aac8b6e0d14896f9acab44f0cc97c4
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

EGLN2 PROSER1

1.34e-03116212f32f7eddfe33adb3b5cf7c34667a481a305c5163
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_mature_2|E18.5-samps / Age Group, Lineage, Cell class and subclass

NFE2 TP73

1.70e-03131212f2eee150f5cff852e8f52f09b35e26f17d80833b
ToppCellwk_08-11-Hematologic-Meg-ery-Definitive_erythrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NFE2 C17orf99

1.70e-03131212537a79ea2b5d6b3dc0444570b1acbceda59b0d7c
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-6|TCGA-Kidney / Sample_Type by Project: Shred V9

FOXH1 TP63

1.73e-0313221279b3443c5cfefa172164625a7b2be469311ba2a8
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Slco2a1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WT1 FRAS1

1.76e-031332129d7a08170d38ae9b2ff10a0fa505aeb3aae2824d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mast-Mast-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NFE2 TP73

1.83e-0313621294eb78a4b8da307c07c2c4f05b8a14424f887579
ToppCellprimary_visual_cortex|World / Per Region, Lineage, Cell class, Cell type, Cell subtype

EGR1 SHISA3

1.97e-03141212605d7b28e99c943f64b4095855a6f9f70e92cb09
ToppCellCOVID-19-Fibroblasts-Mesothelial_FB|COVID-19 / group, cell type (main and fine annotations)

WT1 FRAS1

1.97e-031412127e6dcccb74e7ee90b69dc91b59491b84f3a713c9
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FOXH1 FRAS1

1.97e-03141212d7d3c3932651d90fa4f3c4e3df16f4b677faaf9f
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FOXH1 FRAS1

1.97e-0314121231e0984f09983e83a814424f74c871c1c5a3a789
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasmablast|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TP63 TP73

1.97e-0314121216b96e9f90231e84b5150b5c239599b3dc28b768
ToppCelldroplet-Lung-nan-3m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMKK2 CAP1

2.02e-031432124d11d53330a9197275a8851e1bbf55a113715a09
ToppCelldroplet-Lung-nan-3m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMKK2 CAP1

2.02e-031432128b9f4d87d5faac7752c83e1992491fc5550600f8
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 TP63

2.02e-0314321228e936c298a45f88d14f0146caf3d5a22d483cd5
ToppCellE15.5-Hematopoietic-Erythroid-enucleate_erythrocyte|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NFE2 C17orf99

2.02e-03143212e4207ff9e8248813356631631bbf31a63f23ad3c
ToppCellE15.5-Hematopoietic-Erythroid|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NFE2 C17orf99

2.02e-0314321215a7b93c381ef0f455f99f3abf4b2b9454d35bc4
ToppCellP03-Hematopoietic-Erythroid-enucleate_erythrocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NFE2 C17orf99

2.05e-031442129fa63904389f4d7163db22ea85ab721d8f6e8d99
ToppCellP03-Hematopoietic-Erythroid|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NFE2 C17orf99

2.05e-031442122ee6a834860eac7ed004f366ab4fc38c4b80c905
ToppCelldroplet-Lung-nan-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2 CAMKK2

2.11e-03146212ed932d43e9efd064ee4b49ddef529f3d041be765
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NFE2 C17orf99

2.11e-0314621203a6a442f1f6d173a41aeebbfe41ee08853d9585
ToppCelldroplet-Lung-nan-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2 CAMKK2

2.11e-031462120d74962779055c774312d59fc3b1365163741c3a
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FRAS1 CAMKK2

2.17e-03148212223d6a640f3c34e73646a615593b9c0b4a4cbd6f
ToppCellE12.5-Hematopoietic-Erythroid|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NFE2 C17orf99

2.20e-0314921208e7f76b7e4b53ff734d50dbc853ecfdeb4b371b
ToppCellE12.5-Hematopoietic-Erythroid-enucleate_erythrocyte|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NFE2 C17orf99

2.20e-03149212fb75c1b91b8a0c8221fbbc350666799727b21120
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EGR1 TP63

2.22e-03150212aa11579a57d671a55e64183d35c1340fda6dec14
ToppCellfacs-Trachea-nan-24m-Myeloid-granulocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF12 NFE2

2.25e-0315121226fd55efb647c41436416d45952ee97b050e632c
ToppCellBasal_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 TP63

2.28e-0315221272499e4d2b374ef5f1621c89d94727ecf4bd4d5d
ToppCellfacs-Lung-18m-Hematologic-myeloid-leukocyte-proliferating_myeloid_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NFE2 TP63

2.31e-03153212596bb7cfd1c713708ce73df30d890a0233eae7f7
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EGR1 TP63

2.31e-0315321282b77c8bae49dd63b8f10eb67df66ca71d0bb315
ToppCellPBMC-Control-cDC_8|Control / Compartment, Disease Groups and Clusters

EGR1 ZNF575

2.31e-03153212db1a6914f2033fb0748e0523cffe5d6dc4e901be
ToppCellEnthrocyte|World / shred on cell class and cell subclass (v4)

NFE2 C17orf99

2.31e-03153212105b91f5277d145f7717307d7eb9b7d8e8e23576
ToppCellAdult-Epithelial-basal_cell-D175|Adult / Lineage, Cell type, age group and donor

FRAS1 TP63

2.31e-031532129ee3e7f3f19a2474283c1c79045269686f35a541
ToppCellfacs-Lung-18m-Hematologic-myeloid-leukocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NFE2 TP63

2.31e-031532128cc2667213bfac37545bb63181e88ef1f1834413
ToppCellEnthrocyte|World / shred on cell class and cell subclass (v4)

NFE2 C17orf99

2.31e-03153212654265f3c14344071b2af7ca05cbdbb17ce2c5d3
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

EGR1 NFE2

2.34e-03154212874b1220337276489a89fcc9a39bc81ba6b68baf
ToppCellAdult-Epithelial-basal_cell-D122|Adult / Lineage, Cell type, age group and donor

FRAS1 TP63

2.34e-0315421238d346402417960044ae999e61f0092b46f2b591
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EGR1 NFE2

2.34e-03154212f92d83c5f8b532fe5624f1cd352632f543d96ea9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WT1 ZNF575

2.37e-03155212e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCellBasal_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 TP63

2.37e-0315521230accc72a6a914ae0c4d52b373ea1c9a98efbf22
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WT1 ZNF575

2.37e-031552125a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NFE2 PROSER1

2.37e-0315521277ae0b8d30bc3db4a73fd5340f99691a73d2684f
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Papillary_Adenocarcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

KIF12 NFE2

2.37e-0315521257259549d7ad97d9f628b821417be5ddac7dbff7
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

WT1 FRAS1

2.40e-03156212605d95a900e1443d3f6aae163ef2e893d3293203
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WT1 TP63

2.40e-03156212dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WT1 TP63

2.40e-03156212abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TP73 SHISA3

2.40e-03156212ea9223bb6450b22df11efa1705ab72dab005244a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TP73 SHISA3

2.40e-03156212586b5509074c4cc359e9e31a968c2ded71c994ca
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

WT1 FRAS1

2.40e-03156212574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FRAS1 SHISA3

2.46e-03158212c8af8964a140acb2987e3b4906d72c546108d229
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 TP63

2.46e-03158212d78e7e52657dc094430291fec07e9c298be9e584
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TP63 TP73

2.46e-0315821298712ed7e8e65e8c5ff9318cf0e0a04e271a055d
ToppCellBasal_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 TP63

2.46e-03158212dd069a822e9698e6dddc155d9a5b52383f7879d5
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2 CAMKK2

2.46e-03158212bd37d567754b660bfff7aef81cb307a384ec20a0
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

PER1 EGR1

2.49e-0315921218e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCellfacs-Lung-EPCAM-18m-Hematologic-leukocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2 TP63

2.52e-03160212e6191240c93da34fc4431a35ef496edf323cb41e
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2 C17orf99

2.52e-031602129f24ee4fe1ba4590dce5dd4d43707fb007dca82f
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2 C17orf99

2.52e-031602123b3b99305558f5b49d050fb9b249007630ea9085
ToppCellfacs-Lung-EPCAM-18m-Hematologic-Proliferating_Immune|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2 TP63

2.52e-031602127217730ae14840b935b3bf9aa49becbcbcd8a682
ToppCelldroplet-Marrow-BM-30m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2 CAMKK2

2.52e-03160212822adcf5f9208f305cafffd8ed97f3a061e82b03
ToppCellfacs-Lung-EPCAM-18m-Hematologic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2 TP63

2.52e-03160212317ef81460c1a31b51119a6309b11be6a8d4ea3e
ToppCellfacs-Marrow-T-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXH1 C17orf99

2.56e-0316121279a4a81963c92ade5b6910816a440dc3c233ead2
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PER1 C17orf99

2.56e-0316121278cc5bc488bc47726195a649946d414e6bfabf94
ToppCellwk_08-11-Hematologic-Meg-ery-HMOX1+_primitive_erythroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NFE2 C17orf99

2.56e-031612126079de6cc4f2aec4091d0fac531fda9a441a70b1
ToppCellfacs-Marrow-T-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXH1 C17orf99

2.56e-031612121ce40a6d0f0b9870e7ddb3d607668adcbd3dd1d3
ToppCellPND03-Immune-Immune_Myeloid-DC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOXH1 C17orf99

2.56e-03161212f50e91f8363f20bb7c565aaca4d4961d3fe4b5b5
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-hematologic-erythrocytic-erythrocyte|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NFE2 C17orf99

2.59e-0316221225a11e4c6304324310b33a33331ebc812d045d4a
ToppCell15-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

NFE2 TP63

2.59e-03162212e190c496ed1e206b86566edfee23c99a99fe90d0
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PER1 C17orf99

2.59e-031622120fa93efc9c005d1e649b3f7069ae8641d6e41ed8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EGR1 SHISA3

2.62e-03163212431221a41d396b09170476179590eaf8a55266d8
ToppCellfacs-Liver-Non-hepatocytes-24m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PER1 NFE2

2.62e-03163212abec4389cd88252449f110fe95416d67424b403a
ToppCell11.5-Distal-RBC-RBC|Distal / Age, Tissue, Lineage and Cell class

NFE2 C17orf99

2.62e-0316321231b60e065bac4ad380247964e7574f210106ebae
ToppCell11.5-Distal-RBC|Distal / Age, Tissue, Lineage and Cell class

NFE2 C17orf99

2.62e-03163212e9d814952d824539ff1dea119e4fca14a8c335a8
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TP63 SHISA3

2.62e-031632121eec7f5e5fed05fa21d3f81db588f10605f08ea7
ToppCellfacs-Marrow-T-cells-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXH1 C17orf99

2.62e-03163212c1e9c3b05d407b4dff1cd53de688b43b61128ad0
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EGR1 SHISA3

2.62e-031632121e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCellFrontal_cortex|World / BrainAtlas - Mouse McCarroll V32

EGR1 CAMKK2

2.65e-03164212e09291711abf8680e78170328313719092b0142f
ToppCellBasal_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 TP63

2.65e-0316421285487a303194f5244956ec1ca2d1758d38117f41
ToppCelldroplet-Fat-Gat|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 NFE2

2.65e-03164212c7ad946829c655038b33748dddd7d68c15489034
ToppCelldroplet-Fat-Gat-18m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 NFE2

2.65e-031642123aae702a23fbf1d36a6f18596c23e985581de815
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FOXH1 TP63

2.68e-03165212d8b0a9b6f704b98e8f0412c11739879a26c036e2
ToppCellfacs-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l26|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF12 C17orf99

2.68e-0316521223955e3373660f827518e723ac62fba99753f375
Drughedamycin

WT1 EGR1 NFE2

3.30e-0632213CID000098033
DrugPhentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A

DCAF1 EGR1 TP63 CAMKK2

2.79e-051952143860_UP
DrugPrilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; PC3; HT_HG-U133A

DCAF1 WT1 EGR1 CAMKK2

2.90e-051972143727_UP
DrugMefloquine hydrochloride [51773-92-3]; Down 200; 9.6uM; HL60; HG-U133A

PER1 EGR1 NFE2 CAMKK2

3.02e-051992141364_DN
Diseasetesticular cancer (implicated_via_orthology)

TP63 TP73

4.36e-065202DOID:2998 (implicated_via_orthology)
DiseaseLung Neoplasms

WT1 EGR1 TP63 TP73

2.75e-05265204C0024121
DiseaseMalignant neoplasm of lung

WT1 EGR1 TP63 TP73

2.79e-05266204C0242379
Diseasenephroblastoma (is_implicated_in)

WT1 TP73

3.95e-0514202DOID:2154 (is_implicated_in)
DiseaseMyeloid Leukemia, Chronic

WT1 PER1

1.75e-0429202C0023473
Diseasecervix uteri carcinoma in situ (is_marker_for)

TP63 TP73

3.70e-0442202DOID:8991 (is_marker_for)
Diseaserenal cell carcinoma (is_implicated_in)

EGLN2 TP73

9.96e-0469202DOID:4450 (is_implicated_in)
Diseaselung cancer (is_implicated_in)

TP63 TP73

1.14e-0374202DOID:1324 (is_implicated_in)
DiseasePancreatic Neoplasm

WT1 TP63

2.08e-03100202C0030297
DiseaseMalignant neoplasm of pancreas

WT1 TP63

2.16e-03102202C0346647
Diseaseurinary bladder cancer (is_marker_for)

TP63 TP73

2.37e-03107202DOID:11054 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
CPPPPPVSTISCSYE

CAP1

236

Q01518
PSKTVPPHYPVVCCP

DEDD

141

O75618
PPHYPVVCCPTSGPQ

DEDD

146

O75618
CPPFSLFTPHQCPEP

DCAF1

1026

Q9Y4B6
PSPGYPLVCVTPCDP

FRAS1

3186

Q86XX4
PPTSCPQCPSTSPAY

FOXH1

296

O75593
APAPPCHALPPLYSC

KIF12

486

Q96FN5
TPPHERPYACPVESC

EGR1

331

P18146
EAPCYVSHPSPVPPS

PER1

851

O15534
SQPKPCPPEVTPHYI

PI4KAP1

26

Q8N8J0
YPIPPCRPHATIAPS

PROSER1

201

Q86XN7
CTPPPPYHADPSLVS

TP73

481

O15350
HCTPPPPYPTDCSIV

TP63

536

Q9H3D4
LITCCAPQPPPPITY

C17orf99

46

Q6UX52
PYLTPCVTCPVPTQS

BTAF1

931

O14981
CICPSLPYSPVSSPQ

CAMKK2

121

Q96RR4
PCPLLPSYHCPGVPS

EGLN2

41

Q96KS0
YLGPPPPTTYCPCSI

NFE2

56

Q16621
PPTTYCPCSIHPDSG

NFE2

61

Q16621
GCLVPSPPPPYTTSH

SHISA3

186

A0PJX4
SQPKPCPPEVTPHYI

PI4KAP2

26

A4QPH2
HAPTRPYPCPDCPKS

ZNF575

141

Q86XF7
PYPCPHCPKAFSFPS

ZNF575

176

Q86XF7
PPPVYGCHTPTDSCT

WT1

196

P19544