Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	mucus layer	MUC2 MUC5AC	1.02e-05	3	39	2	GO:0070701
Domain	WxxW_domain	MUC5B MUC2 MUC5AC	1.68e-07	6	39	3	IPR025155
Domain	Mucin2_WxxW	MUC5B MUC2 MUC5AC	1.68e-07	6	39	3	PF13330
Domain	TIL	MUC5B MUC2 MUC5AC	1.83e-06	12	39	3	PF01826
Domain	C8	MUC5B MUC2 MUC5AC	1.83e-06	12	39	3	PF08742
Domain	Unchr_dom_Cys-rich	MUC5B MUC2 MUC5AC	2.37e-06	13	39	3	IPR014853
Domain	C8	MUC5B MUC2 MUC5AC	2.37e-06	13	39	3	SM00832
Domain	TIL_dom	MUC5B MUC2 MUC5AC	3.02e-06	14	39	3	IPR002919
Domain	TMEM9	TMEM9B TMEM9	4.25e-06	2	39	2	IPR008853
Domain	Tmemb_9	TMEM9B TMEM9	4.25e-06	2	39	2	PF05434
Domain	VWFD	MUC5B MUC2 MUC5AC	4.63e-06	16	39	3	PS51233
Domain	VWD	MUC5B MUC2 MUC5AC	4.63e-06	16	39	3	SM00216
Domain	VWF_type-D	MUC5B MUC2 MUC5AC	4.63e-06	16	39	3	IPR001846
Domain	VWD	MUC5B MUC2 MUC5AC	4.63e-06	16	39	3	PF00094
Domain	CTCK_1	MUC5B MUC2 MUC5AC	6.72e-06	18	39	3	PS01185
Domain	VWC_out	MUC5B MUC2 MUC5AC	7.97e-06	19	39	3	SM00215
Domain	CT	MUC5B MUC2 MUC5AC	1.26e-05	22	39	3	SM00041
Domain	Cys_knot_C	MUC5B MUC2 MUC5AC	1.88e-05	25	39	3	IPR006207
Domain	CTCK_2	MUC5B MUC2 MUC5AC	1.88e-05	25	39	3	PS01225
Domain	VWFC_1	MUC5B MUC2 MUC5AC	5.73e-05	36	39	3	PS01208
Domain	VWC	MUC5B MUC2 MUC5AC	6.75e-05	38	39	3	SM00214
Domain	VWFC_2	MUC5B MUC2 MUC5AC	6.75e-05	38	39	3	PS50184
Domain	VWF_dom	MUC5B MUC2 MUC5AC	9.13e-05	42	39	3	IPR001007
Domain	Glyco_hormone_CN	MUC5B MUC5AC	4.39e-04	15	39	2	IPR006208
Domain	Cys_knot	MUC5B MUC5AC	4.39e-04	15	39	2	PF00007
Domain	Znf_MYND	SMYD5 EGLN1	9.56e-04	22	39	2	IPR002893
Domain	ZF_MYND_1	SMYD5 EGLN1	9.56e-04	22	39	2	PS01360
Domain	ZF_MYND_2	SMYD5 EGLN1	9.56e-04	22	39	2	PS50865
Domain	VWC	MUC5B MUC5AC	1.55e-03	28	39	2	PF00093
Domain	LIM	ISL2 MICAL3	9.13e-03	69	39	2	PF00412
Domain	-	ISL2 MICAL3	9.38e-03	70	39	2	2.10.110.10
Domain	LIM_DOMAIN_2	ISL2 MICAL3	9.64e-03	71	39	2	PS50023
Domain	Znf_LIM	ISL2 MICAL3	9.64e-03	71	39	2	IPR001781
Domain	LIM_DOMAIN_1	ISL2 MICAL3	9.64e-03	71	39	2	PS00478
Domain	LIM	ISL2 MICAL3	9.64e-03	71	39	2	SM00132
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC5B MUC2 MUC5AC	4.95e-06	21	23	3	MM15706
Pathway	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	MUC5B MUC2 MUC5AC	1.22e-04	60	23	3	MM15636
Pathway	REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC	MUC5B MUC5AC	3.01e-04	16	23	2	M27410
Pathway	REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS	MUC5B MUC5AC	3.41e-04	17	23	2	M27412
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC5B MUC5AC	6.31e-04	23	23	2	M556
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	MUC5B MUC2 MUC5AC	7.12e-04	109	23	3	MM15164
Pathway	REACTOME_DECTIN_2_FAMILY	MUC5B MUC5AC	8.08e-04	26	23	2	M27483
Pubmed	Mucin gene polymorphisms in otitis media patients.	MUC5B MUC2 MUC5AC	1.41e-09	3	40	3	19718741
Pubmed	Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.	MUC5B MUC2 MUC5AC	5.63e-09	4	40	3	25638393
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC5B MUC2 MUC5AC	5.63e-09	4	40	3	17471237
Pubmed	Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.	MUC5B MUC2 MUC5AC	5.63e-09	4	40	3	22269464
Pubmed	The mouse secreted gel-forming mucin gene cluster.	MUC5B MUC2 MUC5AC	5.63e-09	4	40	3	14984930
Pubmed	Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.	MUC5B MUC2 MUC5AC	5.63e-09	4	40	3	29869461
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC5B MUC2 MUC5AC	5.63e-09	4	40	3	23807779
Pubmed	Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.	MUC5B MUC2 MUC5AC	5.63e-09	4	40	3	12676567
Pubmed	Polymorphism of human mucin genes in chest disease: possible significance of MUC2.	MUC5B MUC2 MUC5AC	1.41e-08	5	40	3	11062147
Pubmed	Differential expression of MUC genes in endometrial and cervical tissues and tumors.	MUC5B MUC2 MUC5AC	1.41e-08	5	40	3	16188033
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC5B MUC2 MUC5AC	2.81e-08	6	40	3	19110483
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC5B MUC2 MUC5AC	1.14e-06	18	40	3	18834073
Pubmed	Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).	MUC5B MUC5AC	1.29e-06	2	40	2	7513696
Pubmed	The lysosomal transmembrane protein 9B regulates the activity of inflammatory signaling pathways.	TMEM9B TMEM9	1.29e-06	2	40	2	18541524
Pubmed	Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: a sequential analysis.	MUC2 MUC5AC	1.29e-06	2	40	2	17203232
Pubmed	Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.	MUC5B MUC5AC	1.29e-06	2	40	2	34058148
Pubmed	The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.	MUC5B MUC5AC	1.29e-06	2	40	2	37146737
Pubmed	MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.	MUC5B MUC5AC	1.29e-06	2	40	2	14988081
Pubmed	Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.	MUC5B MUC5AC	1.29e-06	2	40	2	15563276
Pubmed	The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.	MUC5B MUC5AC	1.29e-06	2	40	2	17621824
Pubmed	Muc5b is required for airway defence.	MUC5B MUC5AC	1.29e-06	2	40	2	24317696
Pubmed	Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.	MUC5B MUC5AC	1.29e-06	2	40	2	22391959
Pubmed	C-Mannosylation of MUC5AC and MUC5B Cys subdomains.	MUC5B MUC5AC	1.29e-06	2	40	2	14718370
Pubmed	Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.	MUC5B MUC5AC	1.29e-06	2	40	2	35776514
Pubmed	Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.	MUC2 MUC5AC	1.29e-06	2	40	2	12527922
Pubmed	Synergistic role of Igf2 and Dlk1 in fetal liver development and hematopoiesis in bi-maternal mice.	DLK1 IGF2	1.29e-06	2	40	2	18344616
Pubmed	The ocular surface phenotype of Muc5ac and Muc5b null mice.	MUC5B MUC5AC	1.29e-06	2	40	2	24327612
Pubmed	Mucin production during prenatal and postnatal murine lung development.	MUC5B MUC5AC	1.29e-06	2	40	2	21653907
Pubmed	MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.	MUC5B MUC5AC	1.29e-06	2	40	2	36427316
Pubmed	Gel-forming mucins form distinct morphologic structures in airways.	MUC5B MUC5AC	1.29e-06	2	40	2	28607090
Pubmed	Mucolytic activity of bacterial and human chitinases.	MUC2 MUC5AC	1.29e-06	2	40	2	17321686
Pubmed	Mucin deficiency causes functional and structural changes of the ocular surface.	MUC5B MUC5AC	1.29e-06	2	40	2	23272068
Pubmed	Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.	MUC5B MUC5AC	1.29e-06	2	40	2	31030254
Pubmed	Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.	MUC5B MUC5AC	1.29e-06	2	40	2	27729120
Pubmed	Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma.	MUC2 MUC5AC	1.29e-06	2	40	2	20731025
Pubmed	The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.	MUC5B MUC5AC	1.29e-06	2	40	2	23527003
Pubmed	Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.	MUC5B MUC5AC	1.29e-06	2	40	2	16540890
Pubmed	De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.	MUC5B MUC5AC	1.29e-06	2	40	2	36111525
Pubmed	Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.	MUC5B MUC5AC	1.29e-06	2	40	2	27845589
Pubmed	In vivo glycosylation of mucin tandem repeats.	MUC2 MUC5AC	1.29e-06	2	40	2	11445551
Pubmed	Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.	MUC5B MUC5AC	1.29e-06	2	40	2	27435107
Pubmed	Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.	MUC5B MUC5AC	1.29e-06	2	40	2	26871672
Pubmed	Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins.	MUC2 MUC5AC	1.29e-06	2	40	2	23832517
Pubmed	Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution.	MUC2 MUC5AC	1.29e-06	2	40	2	23832516
Pubmed	[Interleukin-1beta induces MUC2/MUC5B gene expression in human nasal epithelial cells].	MUC5B MUC2	1.29e-06	2	40	2	20873538
Pubmed	Temporal analysis of goblet cells and mucin gene expression in murine models of allergic asthma.	MUC2 MUC5AC	1.29e-06	2	40	2	14594655
Pubmed	Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.	MUC5B MUC5AC	1.29e-06	2	40	2	32348677
Pubmed	In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.	MUC5B MUC5AC	1.29e-06	2	40	2	11587997
Pubmed	Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.	MUC5B MUC5AC	1.29e-06	2	40	2	24332705
Pubmed	Abnormal subcellular distribution of mature MUC2 and de novo MUC5AC mucins in adenomas of the rectum: immunohistochemical detection using non-VNTR antibodies to MUC2 and MUC5AC peptide.	MUC2 MUC5AC	1.29e-06	2	40	2	12820724
Pubmed	Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.	MUC5B MUC5AC	1.29e-06	2	40	2	34656442
Pubmed	Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.	MUC5B MUC5AC	3.87e-06	3	40	2	27776277
Pubmed	Genetic and non-genetic influences during pregnancy on infant global and site specific DNA methylation: role for folate gene variants and vitamin B12.	MTRR IGF2	3.87e-06	3	40	2	22479380
Pubmed	High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.	MUC5B MUC5AC	3.87e-06	3	40	2	29286856
Pubmed	Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.	MUC5B MUC5AC	3.87e-06	3	40	2	36675209
Pubmed	Differences in the expression of mucins in various forms of cystitis glandularis.	MUC2 MUC5AC	3.87e-06	3	40	2	17659847
Pubmed	Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.	MUC5B MUC5AC	3.87e-06	3	40	2	29802623
Pubmed	Cadherin-catenin adhesion system and mucin expression: a comparison between young and older patients with gastric carcinoma.	MUC2 MUC5AC	3.87e-06	3	40	2	18825309
Pubmed	Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.	MUC2 MUC5AC	3.87e-06	3	40	2	18300795
Pubmed	Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.	MUC5B MUC5AC	3.87e-06	3	40	2	34158522
Pubmed	Gene expression profiling of colorectal mucinous adenocarcinomas.	MUC2 MUC5AC	3.87e-06	3	40	2	20485009
Pubmed	Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.	MUC5B MUC5AC	3.87e-06	3	40	2	29604272
Pubmed	IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.	MUC5B MUC5AC	3.87e-06	3	40	2	19596978
Pubmed	Expression of aberrant mucins in lobular carcinoma with histiocytoid feature of the breast.	MUC2 MUC5AC	3.87e-06	3	40	2	17333267
Pubmed	Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.	MUC5B MUC5AC	3.87e-06	3	40	2	19556605
Pubmed	Clinicopathological and prognostic significance of MUC-2, MUC-4 and MUC-5AC expression in japanese gastric carcinomas.	MUC2 MUC5AC	3.87e-06	3	40	2	23464473
Pubmed	Aquaporin 5 expression increases mucin production in lung adenocarcinoma.	MUC5B MUC5AC	3.87e-06	3	40	2	21455588
Pubmed	Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.	MUC5B MUC5AC	3.87e-06	3	40	2	20422702
Pubmed	Meconium ileus in cystic fibrosis is not linked to central repetitive region length variation in MUC1, MUC2, and MUC5AC.	MUC2 MUC5AC	3.87e-06	3	40	2	24920497
Pubmed	Comparative sequence analysis of the imprinted Dlk1-Gtl2 locus in three mammalian species reveals highly conserved genomic elements and refines comparison with the Igf2-H19 region.	DLK1 IGF2	3.87e-06	3	40	2	11731499
Pubmed	Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas.	MUC2 MUC5AC	7.73e-06	4	40	2	33154304
Pubmed	ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.	MUC5B MUC5AC	7.73e-06	4	40	2	31582416
Pubmed	Gastric mucin expression in first-degree relatives of gastric cancer patients.	MUC2 MUC5AC	7.73e-06	4	40	2	24901817
Pubmed	Evaluation of MUC1, MUC2, MUC5AC, and MUC6 Expression Differences in Lung Adenocarcinoma Subtypes by Using a Final Immunoreactivity Score (FIRS).	MUC2 MUC5AC	7.73e-06	4	40	2	36367122
Pubmed	MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium.	MUC5B MUC5AC	7.73e-06	4	40	2	21097527
Pubmed	TGF-β₂ decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells.	MUC5B MUC5AC	7.73e-06	4	40	2	23249391
Pubmed	Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.	MUC2 MUC5AC	7.73e-06	4	40	2	22691042
Pubmed	Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.	MUC5B MUC5AC	7.73e-06	4	40	2	18258655
Pubmed	[Expression and clinical significance of Mucin and E-cadherin in colorectal tumors].	MUC2 MUC5AC	7.73e-06	4	40	2	17991319
Pubmed	Mucins in neoplastic spectrum of colorectal polyps: can they provide predictions?	MUC2 MUC5AC	7.73e-06	4	40	2	20929551
Pubmed	Appropriate expression of imprinted genes on mouse chromosome 12 extends development of bi-maternal embryos to term.	DLK1 IGF2	7.73e-06	4	40	2	17959172
Pubmed	Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.	MUC5B MUC2	7.73e-06	4	40	2	21596555
Pubmed	Interleukin-1beta induces MUC2 and MUC5AC synthesis through cyclooxygenase-2 in NCI-H292 cells.	MUC2 MUC5AC	7.73e-06	4	40	2	12391274
Pubmed	MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance.	MUC2 MUC5AC	7.73e-06	4	40	2	27298226
Pubmed	PGE(2) induces MUC2 and MUC5AC expression in human intrahepatic biliary epithelial cells via EP4/p38MAPK activation.	MUC2 MUC5AC	7.73e-06	4	40	2	23619266
Pubmed	Mucin expression profile in Barrett's, dysplasia, adenocarcinoma sequence in the esophagus.	MUC2 MUC5AC	7.73e-06	4	40	2	17401217
Pubmed	Expression profile of mucins (MUC1, MUC2, MUC5AC, and MUC6) in ovarian mucinous tumours: changes in expression from benign to malignant tumours.	MUC2 MUC5AC	7.73e-06	4	40	2	25298197
Pubmed	Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14.	MUC2 MUC5AC	1.29e-05	5	40	2	12507512
Pubmed	TRIM28 Controls Genomic Imprinting through Distinct Mechanisms during and after Early Genome-wide Reprogramming.	DLK1 IGF2	1.29e-05	5	40	2	26527006
Pubmed	Comprehensive glycomics comparison between colon cancer cell cultures and tumours: implications for biomarker studies.	MUC5B MUC2	1.29e-05	5	40	2	24840470
Pubmed	Molecular cloning and characterization of a novel member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12.	MUC2 MUC5AC	1.29e-05	5	40	2	12135769
Pubmed	pS2/TFF1 interacts directly with the VWFC cysteine-rich domains of mucins.	MUC2 MUC5AC	1.29e-05	5	40	2	10611155
Pubmed	Divergent expression of MUC5AC, MUC6, MUC2, CD10, and CDX-2 in dysplasia and intramucosal adenocarcinomas with intestinal and foveolar morphology: is this evidence of distinct gastric and intestinal pathways to carcinogenesis in Barrett Esophagus?	MUC2 MUC5AC	1.29e-05	5	40	2	22261707
Pubmed	MUC1, MUC2, MUC4, MUC5AC and MUC6 expression in the progression of prostate cancer.	MUC2 MUC5AC	1.29e-05	5	40	2	16475027
Pubmed	Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.	MUC5B MUC2 MUC5AC	1.46e-05	41	40	3	22675208
Pubmed	Expression of mucin core proteins, trefoil factors, APC and p21 in subsets of colorectal polyps and cancers suggests a distinct pathway of pathogenesis of mucinous carcinoma of the colorectum.	MUC2 MUC5AC	1.93e-05	6	40	2	16142311
Pubmed	Biosynthesis of gastrokine-2 in the human gastric mucosa: restricted spatial expression along the antral gland axis and differential interaction with TFF1, TFF2 and mucins.	MUC2 MUC5AC	1.93e-05	6	40	2	17982272
Pubmed	Mouse Peg9/Dlk1 and human PEG9/DLK1 are paternally expressed imprinted genes closely located to the maternally expressed imprinted genes: mouse Meg3/Gtl2 and human MEG3.	DLK1 IGF2	1.93e-05	6	40	2	11168589
Pubmed	Netrin-1 acts as a repulsive guidance cue for sensory axonal projections toward the spinal cord.	ISL2 UNC5C	1.93e-05	6	40	2	18842897
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KIAA1958 ISL2 MICAL3 PAK1IP1 TOPORS THOC2 ZNF687	2.59e-05	774	40	7	15302935
Cytoband	11p15.5	MUC5B IGF2 MUC2 MUC5AC	3.53e-06	118	40	4	11p15.5
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	MUC5B IGF2 TMEM9B MUC2 MUC5AC	1.27e-04	564	40	5	chr11p15
Cytoband	Ensembl 112 genes in cytogenetic band chrXq25	THOC2 DCAF12L2	8.14e-04	48	40	2	chrXq25
Cytoband	Ensembl 112 genes in cytogenetic band chr1q21	DCST2 DENND4B ZNF687	5.25e-03	404	40	3	chr1q21
GeneFamily	CD molecules\|Mucins	MUC5B MUC2 MUC5AC	4.84e-06	21	29	3	648
GeneFamily	Zinc fingers MYND-type	SMYD5 EGLN1	5.12e-04	21	29	2	87
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORCS2 C2CD4C DCAF12L2 RYR3	1.40e-05	164	40	4	d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	KIAA1958 MUC5B ZNF142 ANAPC7	1.62e-05	170	40	4	aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SORCS2 DLK1 IGF2 DCAF12L2	2.45e-05	189	40	4	eccf3d49354a67c94f1ed7c15a98a48a5e8e2ed0
ToppCell	P03-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SORCS2 DLK1 IGF2 PADI3	2.45e-05	189	40	4	b5439ef221106f6d54434f268485e9bb17b39102
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SORCS2 DLK1 IGF2 DCAF12L2	2.45e-05	189	40	4	40764f461b8aa1d3a2c5a30590b7fb9307d47d09
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SORCS2 DLK1 IGF2 DCAF12L2	2.55e-05	191	40	4	5271198116343c07202649889057e5774d7fdde3
ToppCell	distal-Epithelial-Goblet\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MUC5B MUC2 MUC5AC PADI3	2.88e-05	197	40	4	da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCell	distal-3-Epithelial-Goblet\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MUC5B MUC2 MUC5AC PADI3	2.88e-05	197	40	4	a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCell	distal-Epithelial-Goblet-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MUC5B MUC2 MUC5AC PADI3	2.88e-05	197	40	4	3fbf456ae4f73da4f6254a6f0d24f0ec27d7a3cc
Disease	cystitis (is_marker_for)	MUC2 MUC5AC	1.53e-06	2	37	2	DOID:1679 (is_marker_for)
Disease	sputum mucin-5B amount	MUC2 MUC5AC	4.59e-06	3	37	2	OBA_2050332
Disease	mucinous adenocarcinoma (is_marker_for)	MUC2 MUC5AC	1.53e-05	5	37	2	DOID:3030 (is_marker_for)
Disease	bringing up phlegm, sputum or mucus on most days, self-reported	MUC2 MUC5AC	5.48e-05	9	37	2	EFO_0009824
Disease	cystic fibrosis (is_marker_for)	MUC5B MUC2 MUC5AC	6.52e-05	62	37	3	DOID:1485 (is_marker_for)
Disease	cholangiocarcinoma (is_marker_for)	MUC5B MUC2 MUC5AC	7.17e-05	64	37	3	DOID:4947 (is_marker_for)
Disease	pulmonary fibrosis	MUC5B MUC5AC	8.35e-05	11	37	2	EFO_0009448
Disease	depressive symptom measurement, response to antidepressant	MUC5B DCAF12L2 EGLN1	1.85e-04	88	37	3	EFO_0007006, GO_0036276
Disease	susceptibility to pneumonia measurement	MUC5B MUC5AC UNC5C	2.47e-04	97	37	3	EFO_0008410
Disease	Fetal Growth Retardation	DLK1 IGF2	2.87e-04	20	37	2	C0015934
Disease	COVID-19 symptoms measurement	MUC5B MUC5AC	8.87e-04	35	37	2	EFO_0600019
Disease	Adenoma	MTRR MUC2	9.38e-04	36	37	2	C0001430
Disease	Adenoma, Microcystic	MTRR MUC2	9.38e-04	36	37	2	C0205648
Disease	Adenoma, Monomorphic	MTRR MUC2	9.38e-04	36	37	2	C0205649
Disease	Adenoma, Basal Cell	MTRR MUC2	9.38e-04	36	37	2	C0205646
Disease	Follicular adenoma	MTRR MUC2	9.38e-04	36	37	2	C0205647
Disease	Papillary adenoma	MTRR MUC2	9.38e-04	36	37	2	C0205650
Disease	Adenoma, Trabecular	MTRR MUC2	9.38e-04	36	37	2	C0205651
Disease	phosphatidylethanolamine measurement	ODF1 RYR3 UNC5C	1.33e-03	173	37	3	EFO_0010228
Disease	hepatocellular carcinoma (is_implicated_in)	MTRR IGF2 RYR3	1.51e-03	181	37	3	DOID:684 (is_implicated_in)
Disease	pneumonia	MUC2 MUC5AC	1.60e-03	47	37	2	EFO_0003106
Disease	idiopathic pulmonary fibrosis	MUC5B MUC5AC	2.34e-03	57	37	2	EFO_0000768
Disease	multiple myeloma (is_implicated_in)	MTRR FGG	2.50e-03	59	37	2	DOID:9538 (is_implicated_in)
Disease	pancreatic ductal carcinoma (is_marker_for)	MUC5B MUC5AC	2.67e-03	61	37	2	DOID:3587 (is_marker_for)
Disease	interstitial lung disease	MUC5B MUC5AC	3.21e-03	67	37	2	EFO_0004244

Protein segments in the cluster

Peptide	Gene	Start	Entry
RTCVSLDDGLYECSC	DLK1	101	P80370
GLYDRLCDARSINCC	C2CD4C	331	Q8TF44
LCHDYELRVLCCEYV	MUC5B	1416	Q9HC84
CRLDCYEGLIECYLA	ANAPC7	371	Q9UJX3
RSCFKCEYCATTLRL	MICAL3	786	Q7RTP6
ADYSRFVRDACACLL	MTRR	411	Q9UBK8
CRENVCLTYCDELSL	DCAF12L2	306	Q5VW00
VAAEYCRACRLKSTC	DDX5	186	P17844
DCLCAALSSYARACT	MUC2	626	Q02817
SYLEACRQDLCFCED	MUC5AC	286	P98088
YLTCVDISLDCDLNC	PADI3	111	Q9ULW8
RCIDEFSTRCLCDLY	ODF1	26	Q14990
ICSYLDCERSCEADI	DZIP3	251	Q86Y13
RATALLYRCCFCGED	NR0B1	191	P51843
RDNCCILDERFGSYC	FGG	31	P02679
CFRSCDLALLETYCA	IGF2	71	P01344
LRCSRCRSSFYCCKE	EGLN1	31	Q9GZT9
SCSLCRACDSLVYDE	DENND4B	1156	O75064
LRLDSLSYCQFTRDC	KRCC1	96	Q9NPI7
YCLTCFRLLDNTCSV	DCST2	626	Q5T1A1
RDSVYHIECFRCSVC	ISL2	106	Q96A47
CCLWRRFCATLTYEE	SYT15	26	Q9BQS2
VCDELYIYCSRCTSD	SKIL	186	P12757
NELCKDFCSRYIACL	PKNOX1	136	P55347
CSLYRSCGDCLLARD	SEMA4B	526	Q9NPR2
SRVCECRDSDFLCDY	SORCS2	696	Q96PQ0
TCYHRYCCRDLTLLI	SHISA4	56	Q96DD7
DSRSNAATLYRCCLC	SANBR	316	Q6NSI8
AYCLLCECRYEERST	TMEM9	71	Q9P0T7
CTENEASRYGRFLCC	THOC2	1031	Q8NI27
CLRCECKYEERSSVT	TMEM9B	86	Q9NQ34
ASCCRFLCYFCRISR	RYR3	2091	Q15413
VIRFFDCDSLVCLCE	PAK1IP1	226	Q9NWT1
CLDRFDNVSYLDRCL	TOPORS	106	Q9NS56
ATSAYTCFRCLECKE	ZNF687	666	Q8N1G0
CELCDFTCRDVSYLS	ZNF142	431	P52746
EICISYLDCCQRERS	SMYD5	346	Q6GMV2
CCSSLEYSIRVYCLD	UNC5C	691	O95185
AEELYLCSECGRCFT	ZNF202	561	O95125
LDCNRTRDSCDFSYC	KIAA1958	111	Q8N8K9