Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRab GDP-dissociation inhibitor activity

GDI1 GDI2

4.21e-0521302GO:0005093
GeneOntologyCellularComponentcell projection membrane

CIB1 ANK1 AMN1 APC2 EPB41L5 GPR88 ABCA7 C2CD5 SYNJ2 PIK3CB ENPEP

7.58e-0543112911GO:0031253
DomainRabGDI

GDI1 GDI2

4.52e-0521262IPR000806
DomainPH_dom-like

ARHGEF19 FRMPD1 OBSCN EPB41L5 PREX2 PLEKHH3 NBEAL2 GAB4 TLN2 OSBP2 PLCE1

1.48e-0442612611IPR011993
DomainUbiquitin-rel_dom

FRMPD1 EPB41L5 FAU PIK3CB TLN2 USP48 PLCE1

2.53e-041841267IPR029071
DomainFERM_M

FRMPD1 EPB41L5 PLEKHH3 TLN2

2.59e-04461264PF00373
DomainGDI

GDI1 GDI2

2.69e-0441262PF00996
DomainGDP_dissociation_inhibitor

GDI1 GDI2

2.69e-0441262IPR018203
DomainFERM_central

FRMPD1 EPB41L5 PLEKHH3 TLN2

3.31e-04491264IPR019748
DomainFERM_domain

FRMPD1 EPB41L5 PLEKHH3 TLN2

3.31e-04491264IPR000299
DomainFERM_1

FRMPD1 EPB41L5 PLEKHH3 TLN2

3.58e-04501264PS00660
DomainFERM_2

FRMPD1 EPB41L5 PLEKHH3 TLN2

3.58e-04501264PS00661
DomainFERM_3

FRMPD1 EPB41L5 PLEKHH3 TLN2

3.58e-04501264PS50057
DomainBand_41_domain

FRMPD1 EPB41L5 PLEKHH3 TLN2

3.58e-04501264IPR019749
DomainB41

FRMPD1 EPB41L5 PLEKHH3 TLN2

3.58e-04501264SM00295
Domain-

SEMA7A KIF21A WDR55 DMXL1 MST1R WDR74 NBEAL2 WDR41 GNB3

4.33e-0433312692.130.10.10
DomainWD40/YVTN_repeat-like_dom

SEMA7A KIF21A WDR55 DMXL1 MST1R WDR74 NBEAL2 WDR41 GNB3

4.52e-043351269IPR015943
DomainARM-type_fold

APC2 IPO4 PSME4 PIK3CB NBEAL2 USP35 STKLD1 BRAT1 ARMC6

4.92e-043391269IPR016024
DomainARM-like

APC2 IPO4 PSME4 NBEAL2 USP35 STKLD1 BRAT1 ARMC6

4.97e-042701268IPR011989
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ATMIN PNPLA2 ARHGEF19 SEMA7A OBSCN NCLN SRCAP STK11IP ABCA7 BTN3A2 PLEKHH3 CCND3 LPIN3 MST1R MDN1 PSME4 PTPRF CLN3 NBEAL2 MCM3AP PDCD11 TLN2 HMGXB3 ZNF839 BRAT1 PICK1

8.24e-1411051322635748872
Pubmed

Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.

SRCAP ATXN1L DMXL1 PSME4 PTPRF TLN2 GNB3

4.03e-07120132721697133
Pubmed

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.

TMEM126A IPO4 GDI2 GMPS PTPN2 MDN1 LMO7 BYSL BRAT1 TOP2A

3.25e-064001321035013556
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

TMEM126A WFS1 SUN1 ETFA EPB41L5 IPO4 NCLN C2CD5 DMXL1 WDR74 PTPN2 NEO1 MDN1 DDX18 BYSL PDCD11 WDR41 USP48

1.38e-0514871321833957083
Pubmed

Localization of ank1.5 in the sarcoplasmic reticulum precedes that of SERCA and RyR: relationship with the organization of obscurin in developing sarcomeres.

ANK1 OBSCN

1.43e-052132219002483
Pubmed

Active autophagy but not lipophagy in macrophages with defective lipolysis.

PNPLA2 LIPE

1.43e-052132226143381
Pubmed

Differential expression of Semaphorin-7A /CD163-positive macrophages in large artery and cardiogenic stroke.

SEMA7A CD163

1.43e-052132238373967
Pubmed

Pigment epithelium-derived factor regulates lipid metabolism via adipose triglyceride lipase.

PNPLA2 LIPE

1.43e-052132221464445
Pubmed

Differential transcriptional modulation of biological processes in adipocyte triglyceride lipase and hormone-sensitive lipase-deficient mice.

PNPLA2 LIPE

1.43e-052132218572100
Pubmed

Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia.

PNPLA2 LIPE

1.43e-052132224002947
Pubmed

Relative contribution of adipose triglyceride lipase and hormone-sensitive lipase to tumor necrosis factor-α (TNF-α)-induced lipolysis in adipocytes.

PNPLA2 LIPE

1.43e-052132221969372
Pubmed

Obscurin is a ligand for small ankyrin 1 in skeletal muscle.

ANK1 OBSCN

1.43e-052132212631729
Pubmed

Contraction-induced lipolysis is not impaired by inhibition of hormone-sensitive lipase in skeletal muscle.

PNPLA2 LIPE

1.43e-052132223878361
Pubmed

Adipose triacylglycerol lipase deletion alters whole body energy metabolism and impairs exercise performance in mice.

PNPLA2 LIPE

1.43e-052132219491295
Pubmed

Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state.

PNPLA2 LIPE

1.43e-052132217356053
Pubmed

Mapping the binding site on small ankyrin 1 for obscurin.

ANK1 OBSCN

1.43e-052132217720975
Pubmed

Human adipose triglyceride lipase (PNPLA2) is not regulated by obesity and exhibits low in vitro triglyceride hydrolase activity.

PNPLA2 LIPE

1.43e-052132216752181
Pubmed

Cloning of a brain-type isoform of human Rab GDI and its expression in human neuroblastoma cell lines and tumor specimens.

GDI1 GDI2

1.43e-05213227585614
Pubmed

Mapping, cloning, cDNA sequence, and expression of the gene encoding the mouse micromolar calpain large subunit.

CAPN1 FAU

1.43e-05213229545498
Pubmed

Fasting upregulates adipose triglyceride lipase and hormone-sensitive lipase levels and phosphorylation in mouse kidney.

PNPLA2 LIPE

1.43e-052132225879679
Pubmed

Mild mitochondrial uncoupling induces HSL/ATGL-independent lipolysis relying on a form of autophagy in 3T3-L1 adipocytes.

PNPLA2 LIPE

1.43e-052132228488768
Pubmed

Resveratrol regulates lipolysis via adipose triglyceride lipase.

PNPLA2 LIPE

1.43e-052132221543206
Pubmed

Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis.

PNPLA2 LIPE

1.43e-052132218337240
Pubmed

Adipose tissue deficiency of hormone-sensitive lipase causes fatty liver in mice.

PNPLA2 LIPE

1.43e-052132229232702
Pubmed

Differential role for CD277 as a co-regulator of the immune signal in T and NK cells.

BTN3A2 BTN3A1

1.43e-052132221918970
Pubmed

The molecular basis for modulation of human Vγ9Vδ2 T cell responses by CD277/butyrophilin-3 (BTN3A)-specific antibodies.

BTN3A2 BTN3A1

1.43e-052132222846996
Pubmed

Altered skeletal muscle lipase expression and activity contribute to insulin resistance in humans.

PNPLA2 LIPE

1.43e-052132221498783
Pubmed

Epistatic interaction between the lipase-encoding genes Pnpla2 and Lipe causes liposarcoma in mice.

PNPLA2 LIPE

1.43e-052132228459858
Pubmed

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

PNPLA2 LIPE

1.43e-052132221857651
Pubmed

Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides.

PNPLA2 LIPE

1.43e-052132233372146
Pubmed

Contribution of adipose triglyceride lipase and hormone-sensitive lipase to lipolysis in hMADS adipocytes.

PNPLA2 LIPE

1.43e-052132219433586
Pubmed

Comparative studies of the role of hormone-sensitive lipase and adipose triglyceride lipase in human fat cell lipolysis.

PNPLA2 LIPE

1.43e-052132217327373
Pubmed

Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells.

PNPLA2 LIPE

1.43e-052132225732851
Pubmed

CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells.

BTN3A2 BTN3A1

1.43e-052132221113407
Pubmed

Dietary fat content and adipose triglyceride lipase and hormone-sensitive lipase gene expressions in adults' subcutaneous and visceral fat tissues.

PNPLA2 LIPE

1.43e-052132233445064
Pubmed

Adipose triglyceride lipase contributes to cancer-associated cachexia.

PNPLA2 LIPE

1.43e-052132221680814
Pubmed

Spatially distinct functions of PAX6 and NKX2.2 during gliogenesis in the ventral spinal cord.

RELN DBX1 SULF1

2.89e-0516132319258013
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

SUN1 WDR74 DDX18 MCM3AP BYSL PDCD11 TOP2A DDX28

4.18e-05332132825693804
Pubmed

RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.

GDI1 GDI2

4.28e-053132226240314
Pubmed

Spatially- and temporally-restricted expression of meltrin alpha (ADAM12) and beta (ADAM19) in mouse embryo.

ADAM19 ADAM12

4.28e-05313229622634
Pubmed

ASIC2b-dependent regulation of ASIC3, an essential acid-sensing ion channel subunit in sensory neurons via the partner protein PICK-1.

ASIC2 PICK1

4.28e-053132214976185
Pubmed

The PDZ domain protein PICK1 and the sodium channel BNaC1 interact and localize at mechanosensory terminals of dorsal root ganglion neurons and dendrites of central neurons.

ASIC2 PICK1

4.28e-053132211739374
Pubmed

Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase.

PNPLA2 LIPE

4.28e-053132215550674
Pubmed

Chronic TNFalpha and cAMP pre-treatment of human adipocytes alter HSL, ATGL and perilipin to regulate basal and stimulated lipolysis.

PNPLA2 LIPE

4.28e-053132219695247
Pubmed

CR1, ABCA7, and APOE genes affect the features of cognitive impairment in Alzheimer's disease.

CR1 ABCA7

4.28e-053132224530172
Pubmed

Structural and biochemical characterization of CIB1 delineates a new family of EF-hand-containing proteins.

CIB1 CIB3

4.28e-053132215574431
Pubmed

Cloning and initial characterization of mouse meltrin beta and analysis of the expression of four metalloprotease-disintegrins in bone cells.

ADAM19 ADAM12

4.28e-05313229461614
Pubmed

A metalloprotease-disintegrin participating in myoblast fusion.

ADAM19 ADAM12

4.28e-05313227566181
Pubmed

Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism.

PNPLA2 LIPE

4.28e-053132217074755
Pubmed

Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.

ANK1 OBSCN

4.28e-053132212527750
Pubmed

Expression patterns of two human genes coding for different rab GDP-dissociation inhibitors (GDIs), extremely conserved proteins involved in cellular transport.

GDI1 GDI2

4.28e-05313227543319
Pubmed

Dysregulation of lipolysis and lipid metabolism in visceral and subcutaneous adipocytes by high-fat diet: role of ATGL, HSL, and AMPK.

PNPLA2 LIPE

4.28e-053132220107043
Pubmed

Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle.

GDI1 GDI2

4.28e-05313227513052
Pubmed

Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset.

BTN3A2 BTN3A1

4.28e-053132222767497
Pubmed

Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.

PNPLA2 LIPE

4.28e-053132224440819
Pubmed

Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes.

PNPLA2 LIPE

4.28e-053132217114792
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

SEMA7A WDR55 WDR74 MDN1 BYSL PDCD11 TRMT61B TOP2A

4.95e-05340132829478914
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

EPB41L5 NCLN MDN1 MCM3AP ARMC6

4.97e-05104132531240132
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

KIF21A CAPN1 EPB41L5 IPO4 SRCAP GMPS WDR74 TGM1 FAU MDN1 PSME4 DDX18 MCM3AP BYSL PDCD11 TOP2A

5.70e-0513531321629467282
Pubmed

Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel).

ASIC2 PICK1

8.54e-054132211802773
Pubmed

Clinical and genetic analysis of lipid storage myopathies.

PNPLA2 ETFA

8.54e-054132219208393
Pubmed

Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover.

ANK1 OBSCN

8.54e-054132222573887
Pubmed

Selective modulation of integrin-mediated cell migration by distinct ADAM family members.

ADAM19 ADAM12

8.54e-054132216079176
Pubmed

Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex.

BTN3A2 BTN3A1

8.54e-05413229382921
Pubmed

Cardiotrophin-1 stimulates lipolysis through the regulation of main adipose tissue lipases.

PNPLA2 LIPE

8.54e-054132225351614
Pubmed

Validating GWAS Variants from Microglial Genes Implicated in Alzheimer's Disease.

CR1 ABCA7

8.54e-054132228477215
Pubmed

Analysis of lipolytic protein trafficking and interactions in adipocytes.

PNPLA2 LIPE

8.54e-054132217189257
Pubmed

Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2.

BTN3A2 BTN3A1

8.54e-054132239142074
Pubmed

Non-HLA gene polymorphisms in juvenile idiopathic arthritis: associations with disease outcome.

ADAD1 PTPN2

8.54e-054132228145159
Pubmed

Diet change and exercise enhance protein expression of CREB, CRTC 2 and lipolitic enzymes in adipocytes of obese mice.

PNPLA2 LIPE

8.54e-054132227596982
Pubmed

Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity.

PNPLA2 LIPE

8.54e-054132225535287
Pubmed

Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases.

PNPLA2 LIPE

8.54e-054132223066022
Pubmed

The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells.

ADAM19 ADAM12

8.54e-054132212615925
Pubmed

Molecular interactions with obscurin are involved in the localization of muscle-specific small ankyrin1 isoforms to subcompartments of the sarcoplasmic reticulum.

ANK1 OBSCN

8.54e-054132216962094
Pubmed

A novel Stat3 binding motif in Gab2 mediates transformation of primary hematopoietic cells by the Stk/Ron receptor tyrosine kinase in response to Friend virus infection.

MST1R GAB4

8.54e-054132217353274
Pubmed

GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation.

GDI1 GDI2

1.42e-045132219570034
Pubmed

CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.

CIB1 CIB3

1.42e-045132234089643
Pubmed

Evaluation of the contributions of ADAMs 9, 12, 15, 17, and 19 to heart development and ectodomain shedding of neuregulins beta1 and beta2.

ADAM19 ADAM12

1.42e-045132215936750
Pubmed

Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport.

GDI1 GDI2

1.42e-045132211929610
Pubmed

Heteromeric interactions regulate butyrophilin (BTN) and BTN-like molecules governing γδ T cell biology.

BTN3A2 BTN3A1

1.42e-045132229339503
Pubmed

Patterns of neurogenesis and amplitude of Reelin expression are essential for making a mammalian-type cortex.

RELN DBX1

1.42e-045132218197264
Pubmed

In Vitro Identification of Histatin 5 Salivary Complexes.

BPIFA2 IGHA2 LPO

1.46e-0427132326544073
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KIF21A SUN1 PSME4 SYNJ2 LMO7 SULF1 NBEAL2 PDCD11 HMGXB3

1.98e-04529132914621295
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CAPN1 IPO4 GDI1 GDI2 GMPS MDN1 DDX18 MCM3AP BYSL PDCD11

2.04e-046531321022586326
Pubmed

Localization of Cacna1s to ON bipolar dendritic tips requires mGluR6-related cascade elements.

TRPM1 GNB3

2.12e-046132224519419
Pubmed

The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function.

GDI1 GDI2

2.12e-046132211809807
Pubmed

Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study.

AMN1 LMO7

2.12e-046132223761726
Pubmed

Biophysical and structural studies of the human calcium- and integrin-binding protein family: understanding their functional similarities and differences.

CIB1 CIB3

2.12e-046132222779914
Pubmed

Multiple origins of Cajal-Retzius cells at the borders of the developing pallium.

RELN DBX1

2.12e-046132216041369
Pubmed

Rho-associated protein kinase-dependent moesin phosphorylation is required for PD-L1 stabilization in breast cancer.

PNPLA2 WFS1 CAPN1 GDI2 TGM1 BRAT1

2.23e-04224132632941674
Pubmed

HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation.

PNPLA2 LIPE RETN

2.45e-0432132333732701
Pubmed

Severe obesity is associated with novel single nucleotide polymorphisms of the ESR1 and PPARgamma locus in Han Chinese.

LIPE RETN GNB3

2.45e-0432132319491387
Pubmed

14-3-3ζ coordinates adipogenesis of visceral fat.

PNPLA2 PPARGC1B LIPE

2.93e-0434132326220403
Pubmed

Specific contribution of neurons from the Dbx1 lineage to the piriform cortex.

RELN DBX1

2.97e-047132233863910
Pubmed

The cluster of BTN genes in the extended major histocompatibility complex.

BTN3A2 BTN3A1

2.97e-047132211170752
Pubmed

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.

ZAN CCND3 BYSL

3.20e-0435132319862010
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

RELN CIB1 ADAM19 DIS3L KIF21A APC2 KCNAB2 GDI1 LMO7 SULF1 DDX18 TLN2 SGSM3 PICK1

3.90e-0412851321435914814
Pubmed

Different ADAMs have distinct influences on Kit ligand processing: phorbol-ester-stimulated ectodomain shedding of Kitl1 by ADAM17 is reduced by ADAM19.

ADAM19 ADAM12

3.94e-048132217344430
Pubmed

Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels.

ASIC2 PICK1

3.94e-048132217553932
Pubmed

Regulation of Connexin32 by ephrin receptors and T-cell protein-tyrosine phosphatase.

MST1R PTPN2

3.94e-048132230401746
InteractionTOP3B interactions

ATMIN PNPLA2 ARHGEF19 SEMA7A ETFA OBSCN IPO4 NCLN SRCAP STK11IP ABCA7 BTN3A2 PLEKHH3 CCND3 LPIN3 MST1R MDN1 PSME4 PTPRF CLN3 NBEAL2 MCM3AP BYSL PDCD11 TLN2 HMGXB3 ZNF839 BRAT1 RBM47 DDX28 PICK1

1.96e-09147012831int:TOP3B
Cytoband15q22.3-q23

SEMA7A NEO1

4.90e-054132215q22.3-q23
Cytoband11q14.1

TMEM126A AQP11 USP35

2.46e-0442132311q14.1
Cytoband5q32

PPARGC1B SH3RF2 HMGXB3

5.18e-045413235q32
Cytoband1p36.13

PADI4 ARHGEF19 SELENON

5.76e-045613231p36.13
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

FRMPD1 EPB41L5 PLEKHH3 TLN2

1.37e-04509541293
GeneFamilyWD repeat domain containing

KIF21A WDR55 DMXL1 WDR74 NBEAL2 WDR41 GNB3

4.63e-04262957362
GeneFamilyADAM metallopeptidase domain containing|CD molecules

SEMA7A CR1 BTN3A1 CD163 MST1R CD70 CD180 ENPEP

1.10e-03394958471
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

WFS1 EPB41L5 PTPRF LMO7 SH3RF2 NBEAL2 PLCE1

1.36e-0618513271c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellmild-unassigned|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ARHGEF19 MC1R EPB41L5 TGM1 NEO1 LGR6 TOP2A

1.41e-0618613275b2e1a58916f392fa1156bf9210df528775248ff
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

WFS1 EPB41L5 PTPRF LMO7 SH3RF2 NBEAL2 PLCE1

1.46e-061871327d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

WFS1 EPB41L5 PTPRF LMO7 SH3RF2 NBEAL2 PLCE1

1.46e-06187132777f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellAT1_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

WFS1 EPB41L5 ABCA7 PTPRF LMO7 NBEAL2 PLCE1

1.74e-0619213270444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

WFS1 EPB41L5 PTPRF LMO7 SH3RF2 NBEAL2 PLCE1

2.06e-0619713278d5097898dd01cedb04cb694cb480c931e08462c
ToppCellAT1_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

WFS1 EPB41L5 ABCA7 TGM1 PTPRF LMO7 NBEAL2

2.06e-06197132780d81be244c94c435accb643449b4ce6a3462c7f
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WFS1 EPB41L5 ABCA7 PTPRF LMO7 SH3RF2 NBEAL2

2.28e-062001327c6f211bbadd0c9be776c58807249e06764df47dc
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

WFS1 EPB41L5 ABCA7 PTPRF LMO7 SH3RF2 NBEAL2

2.28e-0620013275f7e8d8b05c90a10313775f9f126eb4ab0fe4f67
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

WFS1 EPB41L5 ABCA7 PTPRF LMO7 SH3RF2 NBEAL2

2.28e-062001327e3a80626941363bfc9d97ef906d38c97080aecb1
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGEF19 FRMPD1 SULF1 SHOC1 CD70 STKLD1

7.48e-061571326a633fb8e7a009490c6002bf272eceaf317f27af6
ToppCellPND01-03-samps|World / Age Group, Lineage, Cell class and subclass

RELN SEMA7A PREX2 MDN1 LMO7 TRPM1

8.63e-0616113261973b112d8d67aacc02751797d0148e7b53bfa66
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DIS3L KCNAB2 ADAM12 MMAA LGR6 TRMT61B

9.26e-061631326e4077e587895c85bc806be05ff5d451088e39468
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRMPD1 EPB41L5 LRTM2 PTPRF LMO7 SH3RF2

1.06e-051671326bebc2493a2ee41920b21c2b774a1c5a9619315c4
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRMPD1 EPB41L5 LRTM2 PTPRF LMO7 SH3RF2

1.06e-0516713269f2661729a2d58e17a9203a563d538c08a3dbbbc
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-ectodermal/neuroectodermal-like_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

KCNAB2 BPIFA2 HASPIN RBM47 TOP2A LRP2BP

1.30e-0517313267e4a2f5f92fbed16406bd097c0119278e4053245
ToppCellP07-Epithelial|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPB41L5 GDE1 C16orf89 PTPRF LMO7 RBM47

1.30e-0517313268b10087a917b825809d35a2b2b349c73a2782472
ToppCellP07-Epithelial-alveolar_epithelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPB41L5 GDE1 C16orf89 PTPRF LMO7 RBM47

1.34e-0517413262739de68e0266054694f99807cfb1f07b6bbb371
ToppCellP15-Epithelial|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPB41L5 GDE1 C16orf89 PTPRF LMO7 RBM47

1.58e-051791326869d3d203e2cb88636e2f0c4476c72571ae3b5ca
ToppCellAT1_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

WFS1 EPB41L5 ABCA7 PTPRF LMO7 NBEAL2

1.63e-0518013262d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCellP15-Epithelial-alveolar_epithelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPB41L5 GDE1 C16orf89 PTPRF LMO7 RBM47

1.68e-0518113267033be0ba90556f7e5f7c0d4a9f7644afcb22c9b
ToppCellP03-Epithelial|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPB41L5 GDE1 C16orf89 PTPRF LMO7 RBM47

1.68e-051811326de0466072f5b2ab8db3d9bab31e3205d1ff7cfb7
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA7A STK11IP LMO7 MCM3AP PDCD11 SGSM3

1.68e-051811326709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCellASK454-Epithelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

WFS1 EPB41L5 TGM1 PTPRF LMO7 PLCE1

1.73e-051821326ab15316cff989b61ff397a866d7ca8b49c13e981
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

WFS1 EPB41L5 PTPRF LMO7 SH3RF2 NBEAL2

1.79e-0518313267b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellIPF-Epithelial-ATI|World / Disease state, Lineage and Cell class

WFS1 EPB41L5 SRCAP PTPRF LMO7 SH3RF2

1.79e-05183132631fef35ecf30162662f24d335d8f0cceacc07039
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRTM2 ADAM12 SULF1 CD70 LGR6 PLCE1

1.79e-05183132625c96df8ea0c7bbedbb7699ee84ad6234d19cba8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPB41L5 CR1 SYNJ2 SULF1 ENPEP PLCE1

1.79e-0518313263c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPB41L5 CR1 SYNJ2 SULF1 ENPEP PLCE1

1.79e-051831326612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellfacs-Marrow-T-cells-3m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WFS1 PLEKHH3 SLC7A3 TRMT61B RBM47 PLCE1

1.79e-051831326b0b835f3b1de1bd46a47e1b805aa8994cd3a4e3e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPB41L5 CR1 SYNJ2 SULF1 ENPEP PLCE1

1.79e-051831326eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPB41L5 CR1 SYNJ2 SULF1 ENPEP PLCE1

1.79e-0518313269c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPB41L5 CR1 SYNJ2 SULF1 ENPEP PLCE1

1.79e-0518313267c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCellIPF-Epithelial-ATI|IPF / Disease state, Lineage and Cell class

WFS1 EPB41L5 SRCAP PTPRF LMO7 SH3RF2

1.79e-051831326c0a3541c45bd0c587603521f392f42dd86c3c35b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ANK1 ZAN OBSCN TLN2 PLCE1

1.84e-0518413262cbed6462fea2622871bb7e49b0df3d984239281
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-FCRL4+_Memory_B|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM19 SEMA7A CIB3 CR1 IGHA2 CD180

1.84e-05184132695cf125127658c4c04445c61809d1aed21ee1f83
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

WFS1 ABCA7 TGM1 LMO7 NBEAL2 SHOC1

1.84e-051841326cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WFS1 EPB41L5 ABCA7 LURAP1L TGM1 LMO7

1.84e-051841326ca940a4f4970285ed284d5517d142abab0682044
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ANK1 ZAN OBSCN TLN2 PLCE1

1.84e-051841326ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ANK1 ZAN OBSCN TLN2 PLCE1

1.84e-0518413262b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

WFS1 ABCA7 TGM1 LMO7 NBEAL2 SHOC1

1.84e-051841326bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

WFS1 EPB41L5 LMO7 SH3RF2 NBEAL2 PLCE1

1.84e-051841326561592edc3083fad41b91811151b442207c65dd9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPB41L5 CR1 SYNJ2 SULF1 ENPEP PLCE1

1.84e-0518413267294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRTM2 ADAM12 SULF1 CD70 LGR6 PLCE1

1.90e-051851326dbbd348714cd16a4948a04648e914b1e71e2a8ef
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRTM2 ADAM12 SULF1 CD70 LGR6 PLCE1

1.90e-051851326bea69058afa5aa927fe15c1f8d46460562ec4dd4
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM19 SEMA7A ADAM12 GDI1 HASPIN ARMC6

1.96e-051861326a558fd00053e7dd6216b01dc8e650c30cee451f1
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM19 SEMA7A ADAM12 GDI1 HASPIN ARMC6

1.96e-05186132675b1f342be5d6dbe0e7acd924a0ca75964f6bab0
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM19 SEMA7A ADAM12 GDI1 HASPIN ARMC6

1.96e-0518613260c3d195077de7b4c354c127a26116438aef29244
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

EPB41L5 PTPRF LMO7 SH3RF2 NBEAL2 PLCE1

1.96e-05186132609d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellE17.5-Epithelial-alveolar_epithelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPB41L5 GDE1 C16orf89 PTPRF LMO7 RBM47

1.96e-051861326a7a2ef8392a045a62fa4d0983577711d5d397dc4
ToppCellE17.5-Epithelial|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPB41L5 GDE1 C16orf89 PTPRF LMO7 RBM47

2.02e-051871326fdabe716ce67f2eede90548198cbe20bbf693570
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 EPB41L5 CR1 SULF1 ENPEP PLCE1

2.02e-05187132624c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellASK454-Epithelial-Type_1|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

WFS1 EPB41L5 TGM1 PTPRF LMO7 PLCE1

2.08e-05188132613f8ce8f24ac7d7ed87f4ae3b8f4096de29383c2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 EPB41L5 CR1 SULF1 ENPEP PLCE1

2.08e-0518813269db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 EPB41L5 CR1 SULF1 ENPEP PLCE1

2.08e-051881326047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

EPB41L5 PTPRF LMO7 SH3RF2 NBEAL2 PLCE1

2.14e-0518913265a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

WFS1 SRCAP ADAM12 CD163 PIK3CB CD180

2.21e-05190132663018acb7ad80415e861643162abdc2e55968ee4
ToppCellLAM-Epithelial-AT1|LAM / Condition, Lineage and Cell class

WFS1 EPB41L5 SRCAP ABCA7 PTPRF LMO7

2.27e-05191132666875b2ec2c510489407f3e433a90cdf74a15094
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPB41L5 LRTM2 C16orf89 PTPRF LMO7 SH3RF2

2.27e-051911326ce76b156b153a2c7c9f2fb8e563b69c81073fbe5
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPB41L5 LRTM2 C16orf89 PTPRF LMO7 SH3RF2

2.27e-051911326c006f5a6e3a32b79ac99a78304bdd5116fc0d5e0
ToppCellP03-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPB41L5 GDE1 C16orf89 LURAP1L PTPRF LMO7

2.34e-051921326be5e246b2350398b985767b2fbede17a8dd8cc44
ToppCellwk_08-11-Hematologic-Meg-ery-Definitive_erythroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RELN ANK1 SEMA7A CR1 ABCA7 OSBP2

2.41e-051931326be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCellAT1_cells|World / lung cells shred on cell class, cell subclass, sample id

WFS1 EPB41L5 ABCA7 PTPRF LMO7 NBEAL2

2.55e-051951326792d6a49b0a875a00569071183d195287a9925c5
ToppCellAT1|World / shred by cell class for parenchyma

ABCA7 TGM1 LMO7 SH3RF2 NBEAL2 TOP2A

2.63e-0519613262bc487f8a109a6961ebff111dec79c2227ea60ac
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

WFS1 EPB41L5 ABCA7 PTPRF LMO7 NBEAL2

2.63e-0519613266731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

WFS1 EPB41L5 ABCA7 PTPRF LMO7 NBEAL2

2.63e-0519613266856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPB41L5 ZNF407 SELENON ATXN1L BRAT1 DDX28

2.70e-051971326789c97ca9d1e28df3353140046047f11fbccc1d0
ToppCellBiopsy_IPF-Epithelial-AT1|Biopsy_IPF / Sample group, Lineage and Cell type

WFS1 EPB41L5 ABCA7 TGM1 LMO7 PLCE1

2.78e-05198132675bdecbe111fededf6082b11de18b84ca308ef6d
ToppCellControl_saline-Epithelial_alveolar-AT_1-2_Progenitor-Progenitor_AT1-AT2|Control_saline / Treatment groups by lineage, cell group, cell type

KIF21A EPB41L5 C16orf89 PTPRF LMO7 RBM47

2.78e-051981326827aa9d919bf6d670961e5501e17d351676127e3
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

KIF21A EPB41L5 PTPRF LMO7 NBEAL2 PLCE1

2.78e-05198132685f424cd9bb3117c9e322031024aabb87696ce47
ToppCellControl_saline-Epithelial_alveolar-AT_1|Control_saline / Treatment groups by lineage, cell group, cell type

KIF21A EPB41L5 PTPRF LMO7 NBEAL2 PLCE1

2.78e-0519813269b161285df7a4e51618f3517cfc5b8221ba55786
ToppCellControl_saline-Epithelial_alveolar|Control_saline / Treatment groups by lineage, cell group, cell type

KIF21A EPB41L5 C16orf89 PTPRF LMO7 RBM47

2.78e-051981326532b7ef4ad46fe35ad2c6bdf89f70a17f1a2e2e2
ToppCellLPS_IL1RA-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ANK1 CCND3 IGHA2 PIK3CB NBEAL2 TRPM1

2.94e-052001326326cae37cacd94b423a6ac8873ea56c5abaf0a0b
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

KIF21A EPB41L5 PTPRF LMO7 SH3RF2 NBEAL2

2.94e-052001326ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_alveolar-AT1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

WFS1 EPB41L5 ABCA7 PTPRF LMO7 NBEAL2

2.94e-0520013263d51aebf626dd4656ab4aac8a20d761b8062c42d
ToppCellCOVID-19-COVID-19_Severe|COVID-19 / Disease, condition lineage and cell class

PADI4 ANK1 CR1 RETN IGHA2 OSBP2

2.94e-0520013263ec89071f002bb66d46146bf4804f91e6f09a36f
ToppCellwk_08-11-Epithelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

COL27A1 KIF21A C16orf89 PTPRF LMO7 RBM47

2.94e-052001326445fc7995ffc440c6256a6aab0bbf33fb0fea028
ToppCell18-Distal-Epithelial-Bud_tip_adjacent|Distal / Age, Tissue, Lineage and Cell class

PNPLA2 EPB41L5 SRCAP CCND3 LMO7 RBM47

2.94e-0520013263c231d0a5809eab0acd6d0a77d54c49ac3eaaff3
ToppCellmild-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MC1R EPB41L5 TGM1 NEO1 LGR6 TOP2A

2.94e-052001326ca0a08bf162c954f037a56aa0cbb8b5d7c6ffec0
ToppCellCOVID_vent|World / Disease condition, Lineage, Cell class and subclass

ADAM19 CR1 RETN IGHA2 CD180 TOP2A

2.94e-0520013261d88e5cc4534073f27a7562e1c4b884bd67f09d9
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocye.Tnr.Cspg5_(Cspg5)|Striatum / BrainAtlas - Mouse McCarroll V32

ZAN ADAM12 LPO CD70

5.59e-05701324c6d3f8cd3f79e2beb826b07a6b9f3ab35d4f23ea
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocye.Tnr.Cspg5_(Cspg5)-|Striatum / BrainAtlas - Mouse McCarroll V32

ZAN ADAM12 LPO CD70

5.59e-05701324823921f8bf585d45f24f627b2b77b228898eb85a
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P3-Tnr|Striatum / BrainAtlas - Mouse McCarroll V32

ZAN ADAM12 LPO CD70

5.59e-05701324d2be16550c572ba77261c978648e61dba3eab6bd
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P3|Striatum / BrainAtlas - Mouse McCarroll V32

ZAN ADAM12 LPO CD70

5.59e-0570132452bde49a05f2387fe3e4357422e155bee2e86ae6
ToppCellcontrol-Myeloid-CD14_Monocytes_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

WFS1 RETN TRPM1 CD180 DDX28

5.71e-05138132574087d94f993b9efa4a6e1ee35451a27cf341c4b
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PADI4 C11orf87 PPARGC1B RETN BRAT1

9.31e-051531325489228ab81c3ae339a53a9da6c2a1c1b6ac3f84b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPB41L5 CR1 SULF1 ENPEP PLCE1

9.89e-05155132590e629681a72baacc7981b82883866a487638dbc
ToppCell343B-Lymphocytic-Plasma_cell-|343B / Donor, Lineage, Cell class and subclass (all cells)

CIB3 IGHA2 GNB3 CD180 OCSTAMP

1.05e-041571325554ddbaf83f5d6eb4669c673efdbb28fd87e2ba8
ToppCell343B-Lymphocytic-Plasma_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

CIB3 IGHA2 GNB3 CD180 OCSTAMP

1.05e-0415713252cb3deb5313ce734710c601935ca318e4179077e
ToppCellfacs-Thymus-Flowthrough-24m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAD1 AQP11 CCND3 MMAA PTPRF

1.08e-041581325c870fd17213129943562487338e2669e2930d719
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 LRFN5 TRPM1 LGR6 PRSS48

1.15e-04160132541d6c811c445c0ba9b6a2deb10a3b6b793172582
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK1 LRFN5 TRPM1 LGR6 PRSS48

1.15e-041601325c1d03c0ac9c12615a06499209fcdf18e9b6f1fba
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD163 RETN PIK3CB LPO RBM47

1.15e-0416013256ed37d1fd0304932319d6b942502404115ff36a7
ToppCell368C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

PADI4 SEMA7A AQP11 LIPE PTPRF

1.25e-041631325299ac2463b7f58eee419d822a2a2d64b973d87e9
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B0|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ANK1 FRMPD1 CD70 OSBP2 USP35

1.33e-041651325ebd668e87e5961a124d1d6fc25d1f03e4af05cd4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 CIB3 ABCA7 BTN3A1 USP48

1.40e-0416713250130743084dbcb20e10f96715d30961122150cbf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 CIB3 ABCA7 BTN3A1 USP48

1.40e-0416713257bcae3797d3a0811e7f39885afdfd29ec517f11b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 CIB3 ABCA7 BTN3A1 USP48

1.40e-041671325c6f0209a1ad797631fdfa3efab6db6b1d3e8e315
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SERHL2 ADAM19 LPIN3 TGM1 IGHA2

1.44e-0416813256501495b7ad252af330b18011696c43031541018
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C11orf87 GPR88 RETN SH3RF2 LRFN5

1.44e-041681325b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
DiseaseMalignant neoplasm of breast

ANK1 APC2 FRMPD1 OBSCN ADAM12 BTN3A2 CUTC PPARGC1B LIPE SYNJ2 PIK3CB DDX18 LGR6 ENPEP TOP2A

6.73e-05107412815C0006142
Diseaseaspartate aminotransferase measurement

ARHGEF19 SUN1 ETFA OBSCN WDR55 CD163 PRUNE1 CUTC HMGXB3 WDR41 STKLD1 PLCE1 ARMC6

1.59e-0490412813EFO_0004736
Diseaseresponse to risperidone

HMGXB3 TRPM1 USP48

6.02e-04381283GO_0097336
DiseaseNight blindness, congenital stationary, type 1

TRPM1 GNB3

1.20e-03121282C3501847
DiseaseNight Blindness, Congenital Stationary, Type 1A

TRPM1 GNB3

1.20e-03121282C3495587
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)

TRPM1 GNB3

1.20e-03121282C1864877
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B

TRPM1 GNB3

1.20e-03121282C1850362
DiseaseX-Linked Csnb

TRPM1 GNB3

1.20e-03121282C3711543
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A

TRPM1 GNB3

1.20e-03121282C1848172
DiseaseCone-rod synaptic disorder, congenital nonprogressive

TRPM1 GNB3

1.41e-03131282C4041558
Diseasethalamus volume change measurement

ASIC2 LRFN5

1.64e-03141282EFO_0021496
DiseaseNight blindness, congenital stationary

TRPM1 GNB3

2.43e-03171282C0339535
DiseaseMHPG measurement, 5-HIAA measurement

ADAM12 CCND3

2.43e-03171282EFO_0005132, EFO_0005133
Diseasefreckles

MC1R PPARGC1B

3.37e-03201282EFO_0003963
Diseaseskin pigmentation

MC1R OSBP2 USP48

3.39e-03691283EFO_0003784
Diseaseceramide measurement

SERHL2 ADAM19 ABCA7 MDN1 OSBP2

3.67e-032351285EFO_0010222
DiseaseDown syndrome (is_marker_for)

RELN GDI2

4.07e-03221282DOID:14250 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
LGATVTVLRLCDGSA

BRAT1

391

Q6PJG6
VCLVQLLGTGTDSSE

C16orf89

161

Q6UX73
IDLGGCLSITDVSLH

AMN1

146

Q8IY45
TELLAGITGTEVDCL

CCND3

226

P30281
CVLETLGGSSLAALR

BLACE

121

A4D250
EGVSCTIRSSLLGLE

BTN3A1

216

O00481
SVTLSTCRGIRGLIT

ADAM19

126

Q9H013
DSGEGDTTSLRLLCS

ANK1

1161

P16157
DTTSLRLLCSVIGGT

ANK1

1166

P16157
GILSELCGTLSRLAI

ARMC6

291

Q6NXE6
SAVSLSTCSGLRGLI

ADAM12

131

O43184
ISSILIGDGNCSDTR

ADAD1

411

Q96M93
GLGTDESVLIEVLCT

ANXA13

101

P27216
ALERGSLLGCSIDIS

CAPN1

241

P07384
GSLEVLILSSCGLLS

CD180

496

Q99467
LARGDTLCTNLTGTL

CD70

161

P32970
GITCLIRLLNSSGEE

DMXL1

2296

Q9Y485
LVGTLGRVTECLSLD

ABCA7

396

Q8IZY2
GSLGLLLVESSERVS

ASIC2

51

Q16515
LNGTELEGSCLEVTL

RBM47

301

A0AV96
GRSGTFSLVDTCLVL

PTPN2

221

P17706
TGARCLEVSISDGLF

MC1R

31

Q01726
AFVLCLDTVGRGSSL

NCLN

306

Q969V3
DDGITSLTATRVVGC

LRFN5

491

Q96NI6
VRGSGVLATLSLRDC

ARHGEF19

361

Q8IW93
TGVEISLCADITRTG

PADI4

111

Q9UM07
GSCATLVTERILQGA

PRUNE1

146

Q86TP1
LTATALVTGVCLGEA

PNPLA2

51

Q96AD5
TLDTVDTIALSLCGG

LPIN3

431

Q9BQK8
DTIALSLCGGLADSR

LPIN3

436

Q9BQK8
DVIVLGTGLTECILS

GDI2

6

P50395
GASEVRLDTLTILGS

KIAA0100

591

Q14667
LECLSGLLEGSSGSL

MDN1

846

Q9NU22
STTGGSLLLLCEEEE

GPR88

11

Q9GZN0
TGISCGLLASVDALT

LGR6

611

Q9HBX8
TVLGSRELCDSEGKS

ATXN1L

611

P0C7T5
LRGLDTTDIGTCAIT

KIAA1109

1831

Q2LD37
LQLSEATGTCLGERL

MCM3AP

1936

O60318
SCTVTLDLGLATSRG

HMGXB3

606

Q12766
SLDLTSLSLEVGCGA

LPO

111

P22079
ERELLSSGGCREQTL

DBX1

241

A6NMT0
LISCSGDTGSLILAD

GANC

111

Q8TET4
LLCTDIASRGLDSTG

DDX28

451

Q9NUL7
RSLTSCSSDITLRGG

LMO7

256

Q8WWI1
CLQLGLGITRDETTA

LRP2BP

306

Q9P2M1
TRTTNEAILLCEGAG

MMAA

221

Q8IVH4
CGITSVAFSLSGRLL

GNB3

271

P16520
LIVGLAVGLTRSCDS

ENPEP

31

Q07075
SGTLLCTDVAARGLD

DDX18

476

Q9NVP1
DTEDSCGILLTSGAR

OSBP2

236

Q969R2
CLRNEGVSSVLLGAS

KCNAB2

311

Q13303
GGCSRLLVTVDLNLT

RELN

2556

P78509
VCGRVFLSLEDLSTG

FANCB

616

Q8NB91
VLEGGAATLRCVLSS

OBSCN

3196

Q5VST9
IDQLGDGTCSLLITG

OBSCN

4946

Q5VST9
DGTCSLLITGLDRAD

OBSCN

4951

Q5VST9
RTRGDGALQSLCLTT

APC2

1486

O95996
LSVGTLILGLDSEAC

ATMIN

346

O43313
SIITCRVSLLDGTDV

EPB41L5

41

Q9HCM4
VDRTTDGTGRLCDLT

GDE1

116

Q9NZC3
VLLSGGVDSTVCTAL

GMPS

241

P49915
CGVLTGTSESLLDNL

BPIFA2

11

Q96DR5
RLIGSSSATCIISGD

CR1

136

P17927
RGTSFDLIGESTIRC

CR1

456

P17927
RGTSFDLIGESTIRC

CR1

906

P17927
RSQGVTLCGDVLLIS

DNAH17

3346

Q9UFH2
DICVVGSTSGARALI

PIK3CD-AS1

61

Q5SR53
ERSGIETSGFLCLLD

FRMPD1

646

Q5SYB0
LVGLSDSIASEGSCV

GAB4

346

Q2WGN9
SVLSADLCSLLGGVD

DIS3L

541

Q8TF46
LELRGRTVTLVTACG

COL27A1

161

Q8IZC6
EGVSCIIRNSLLGLE

BTN3A2

216

P78410
RGSSLSGSLCSLLES

LURAP1L

141

Q8IV03
ELSLLSGEVCNRTEG

HASPIN

541

Q8TF76
LLTLGFERVLTSGCD

CUTC

161

Q9NTM9
DVIVLGTGLTECILS

GDI1

6

P31150
LGSEANLTCTLTGLR

IGHA2

126

P01877
AGVTCSDGSDLELRL

CD163

361

Q86VB7
LSEECGELLLQRGTT

SERHL2

186

Q9H4I8
VLEALTGVLRSCGTL

IPO4

771

Q8TEX9
ESGLVVRAIGTACTL

C2CD5

231

Q86YS7
ESGTCTLREAIIVGS

BYSL

296

Q13895
CLSTLDLVALGVGST

SLC7A3

31

Q8WY07
LLGSTGERICLAGDS

LIPE

711

Q05469
ARGTETCGLIQVTLL

PTPRF

1466

P10586
TLRSGVVSVVDSLLC

PAMR1

616

Q6UXH9
LLRESGDVVLSGCST

STK11IP

16

Q8N1F8
GDVVLSGCSTLSLLT

STK11IP

21

Q8N1F8
RLGSLVLTSLCSVTG

PLEKHH3

141

Q7Z736
LDCETCTITRSGLTG

TMEM126A

96

Q9H061
LSFLVLVTGCTSVGR

SYNJ2

76

O15056
DSRSLEVDCSGLGLT

LRTM2

46

Q8N967
ITGSLLEATTSLGAR

PLCE1

466

Q9P212
ITAATRLGGEVSCLV

ETFA

41

P13804
GCLLETLSTGLALEA

NBEAL2

496

Q6ZNJ1
TESSERLVLLAGGSL

NEO1

291

Q92859
EQTLTVELCGTAGLT

PPARGC1B

591

Q86YN6
SVTEGVTDLVRGTLC

SGSM3

551

Q96HU1
LESEGVLRGTSSCVV

SHOC1

781

Q5VXU9
ADITLSGCASGLVRV

SLC25A47

96

Q6Q0C1
GQVLRCVTEGSLESL

OCSTAMP

146

Q9BR26
CLATGDRSGLIEVVS

PIK3CB

841

P42338
DRDSTSVLESCGLGR

SRCAP

3026

Q6ZRS2
GLTSCAVEGRLSSLL

OR6B3

306

Q8NGW1
LSGLLQVCVRTGTET

ABCC12

1066

Q96J65
GLRSELQDTCTSLGL

AQP11

6

Q8NBQ7
LVNCLTGEGEDTRLS

CIB1

131

Q99828
ATCISDTLGISLSGL

CLN3

411

Q13286
TRGGLSAEEVSLVCE

CIB3

136

Q96Q77
SCLDTAGEGLLQTVV

C11orf87

181

Q6NUJ2
SLRLSDCGLGDLAIT

PDCD11

796

Q14690
ADGTLITCVDSGILR

WDR74

96

Q6RFH5
RVLECVATGTLLTDG

ZFR2

836

Q9UPR6
DIGTGCLSSLENLRL

TRMT61B

76

Q9BVS5
SLESRDVCASGLGLL

STKLD1

471

Q8NE28
CIRTLTSSGQVTLGD

KIF21A

1421

Q7Z4S6
TSTVGLFLDCEGRTV

TRIM51

406

Q9BSJ1
RTCGSEGSRSVLDLV

USP35

751

Q9P2H5
CUGSGRTLRETVLES

SELENON

461

Q9NZV5
EATLGQCGVEALTTL

nan

76

A6NDN8
TLLERRSEGLLACGT

SEMA7A

131

O75326
SGVGLLSVSSELCNR

PREX2

1506

Q70Z35
TLSCVIGVARSLVSG

PSME4

456

Q14997
FICGGSLVSERLILT

PRSS48

51

Q7RTY5
SGSTLRGCTEERTLS

ZNF839

236

A8K0R7
RGCTEERTLSLTSLG

ZNF839

241

A8K0R7
VVICDGSGRASDILS

TRPM1

276

Q7Z4N2
DAGGRNSTECTLILT

TOP2A

446

P11388
LLCTGSTDGVIRAVN

WDR55

266

Q9H6Y2
GELLVTICSRIGITN

TLN2

111

Q9Y4G6
LTGEPALTCISRGSE

SH3RF2

576

Q8TEC5
AGVTTTVLRCLGLAT

TGM1

381

P22735
LRLATTACTLGDGEA

SUN1

56

O94901
EATLGQCGVEALTTL

FAU

51

P62861
ICRLETSESSVTEGG

ZNF407

91

Q9C0G0
SIGLECQSVTSRGDL

RETN

46

Q9HD89
ILSDDCATLGTLGVI

USP48

981

Q86UV5
SGTADALGLSRAILC

PICK1

131

Q9NRD5
AVLGTELLGSLCSTV

SULF1

11

Q8IWU6
CLTLEGQSLSVGTSR

MST1R

701

Q04912
GTECLLARVSEGQLL

MST1R

721

Q04912
TSCSLELIGDLIGHS

WDR41

391

Q9HAD4
CELSVVILLESTGLG

WFS1

541

O76024
AELGLRTGLQVSECS

ZAN

2521

Q9Y493