Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of presynaptic active zone	RIMS1 BSN	2.46e-04	8	60	2	GO:0098882
GeneOntologyMolecularFunction	transcription factor binding	MED24 MLXIPL JUND HOXC13 AHR UBA3 BSN FEM1A TP53BP2	3.88e-04	753	60	9	GO:0008134
GeneOntologyMolecularFunction	ubiquitin-like modifier activating enzyme activity	ATG7 UBA3	3.93e-04	10	60	2	GO:0008641
GeneOntologyCellularComponent	cytoskeleton of presynaptic active zone	RIMS1 BSN	2.17e-04	8	59	2	GO:0048788
GeneOntologyCellularComponent	cell cortex region	SPTBN5 RIMS1 BSN	2.79e-04	45	59	3	GO:0099738
GeneOntologyCellularComponent	presynaptic cytoskeleton	RIMS1 BSN	6.97e-04	14	59	2	GO:0099569
Domain	PH_dom-spectrin-type	SPTBN5 PSD3	3.25e-04	9	57	2	IPR001605
Domain	ThiF_NAD_FAD-bd	ATG7 UBA3	4.05e-04	10	57	2	IPR000594
Domain	ThiF	ATG7 UBA3	4.05e-04	10	57	2	PF00899
Domain	-	MLXIPL SREBF2 AHR	4.50e-03	109	57	3	4.10.280.10
Domain	HLH	MLXIPL SREBF2 AHR	4.73e-03	111	57	3	PF00010
Domain	Ank	CAMTA1 FEM1A ANKRD52 TP53BP2	5.15e-03	228	57	4	PF00023
Domain	HLH	MLXIPL SREBF2 AHR	5.35e-03	116	57	3	SM00353
Domain	BHLH	MLXIPL SREBF2 AHR	5.48e-03	117	57	3	PS50888
Domain	bHLH_dom	MLXIPL SREBF2 AHR	5.61e-03	118	57	3	IPR011598
Domain	-	CAMTA1 FEM1A ANKRD52 TP53BP2	6.91e-03	248	57	4	1.25.40.20
Domain	ANK	CAMTA1 FEM1A ANKRD52 TP53BP2	7.20e-03	251	57	4	SM00248
Domain	VWF_dom	PXDNL OTOG	7.29e-03	42	57	2	IPR001007
Domain	ANK_REPEAT	CAMTA1 FEM1A ANKRD52 TP53BP2	7.41e-03	253	57	4	PS50088
Domain	Ankyrin_rpt-contain_dom	CAMTA1 FEM1A ANKRD52 TP53BP2	7.51e-03	254	57	4	IPR020683
Domain	ANK_REP_REGION	CAMTA1 FEM1A ANKRD52 TP53BP2	7.51e-03	254	57	4	PS50297
Domain	Ankyrin_rpt	CAMTA1 FEM1A ANKRD52 TP53BP2	8.35e-03	262	57	4	IPR002110
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MLXIPL HIVEP1 ALMS1 PHF3 PRRC2C PSD3 OSBPL10 FAM117B TP53BP2 OTOG	2.02e-06	861	60	10	36931259
Pubmed	ASPP2 inhibits hepatitis B virus replication by preventing nucleus translocation of HSF1 and attenuating the transactivation of ATG7.	ATG7 TP53BP2	8.77e-06	3	60	2	34085409
Pubmed	Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.	LIN28B CAMTA1	1.75e-05	4	60	2	24770850
Pubmed	Dioxin induces expression of c-fos and c-jun proto-oncogenes and a large increase in transcription factor AP-1.	JUND AHR	2.92e-05	5	60	2	1605850
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	AFF2 PHF3 RIMS1 BSN OTOG	3.05e-05	208	60	5	33230847
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	HIVEP1 PHF3 PRRC2C CPLANE1 NUP153 REV1	3.75e-05	361	60	6	26167880
Pubmed	A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.	RIMS1 BSN	4.37e-05	6	60	2	19812333
Pubmed	Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B.	CHST15 NOL8	4.37e-05	6	60	2	11073942
Pubmed	Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release.	RIMS1 BSN	4.37e-05	6	60	2	14734538
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	HIVEP1 HOXC13 ALMS1 PHF3 BSN	5.23e-05	233	60	5	37704626
Pubmed	Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-α axis.	HOXC13 TNFRSF1B	8.14e-05	8	60	2	34624205
Pubmed	Gene expression profiling in human skeletal muscle during recovery from eccentric exercise.	JUND SREBF2	8.14e-05	8	60	2	18321953
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	MED24 SHLD2 DDX52 HSPH1 SREBF2 CAMTA1 ITGA9 CPLANE1 NUP153	9.52e-05	1084	60	9	11544199
Pubmed	BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade.	HLTF REV1	1.05e-04	9	60	2	23901102
Pubmed	Superresolution imaging of chemical synapses in the brain.	RIMS1 BSN	1.05e-04	9	60	2	21144999
Pubmed	Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.	GRIK4 RIMS1 RAI1	1.56e-04	60	60	3	32027825
Pubmed	Common genetic variation and performance on standardized cognitive tests.	GRIK4 RIMS1 CAMTA1	1.72e-04	62	60	3	20125193
Pubmed	Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair.	BSN NUP153	1.91e-04	12	60	2	28700933
Pubmed	Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects.	DAGLB SREBF2 OSBPL10	2.16e-04	67	60	3	16806233
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	HIVEP1 HOXC13 LIN28B PHF3 PRRC2C NUP153 RAI1 NOL8	2.25e-04	954	60	8	36373674
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	HIVEP1 LIN28B HLTF OSBPL10 UBA3 FEM1A ANKRD52 NUP153	3.20e-04	1005	60	8	19615732
Pubmed	Tail Bud Progenitor Activity Relies on a Network Comprising Gdf11, Lin28, and Hox13 Genes.	HOXC13 LIN28B	3.46e-04	16	60	2	30661984
Pubmed	An interactive association of common sequence variants in the neuropeptide Y gene with susceptibility to ischemic stroke.	SREBF2 F13B	4.40e-04	18	60	2	17702963
Pubmed	Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.	MLXIPL AHR	4.40e-04	18	60	2	25288136
Pubmed	An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.	MED24 SREBF2	4.91e-04	19	60	2	16799563
Pubmed	Discovery and refinement of loci associated with lipid levels.	DAGLB MLXIPL ATG7 FAM117B	4.92e-04	211	60	4	24097068
Pubmed	Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study.	LIN28B BSN	5.45e-04	20	60	2	20846217
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	MED24 JUND HIVEP1 PRRC2C HSPH1 HLTF NUP153 RAI1	5.92e-04	1103	60	8	34189442
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	DDX52 HSPH1 HLTF NUP153 RAI1	5.96e-04	394	60	5	27248496
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ALMS1 PHF3 PSD3 CAMTA1	6.26e-04	225	60	4	12168954
Pubmed	Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.	MLXIPL SREBF2 AHR	6.61e-04	98	60	3	18557763
Pubmed	Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).	MLXIPL SREBF2	6.61e-04	22	60	2	20965718
Pubmed	Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemia.	AFF2 SMCP	6.61e-04	22	60	2	16024815
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CHST15 PHF3 PRRC2C PSD3 CAMTA1	6.90e-04	407	60	5	12693553
Pubmed	Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.	MLXIPL SREBF2	7.23e-04	23	60	2	26508642
Pubmed	A general approach for investigating enzymatic pathways and substrates for ubiquitin-like modifiers.	UBA3 TP53BP2	7.88e-04	24	60	2	16620772
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	AFF2 CAMTA1 BSN NUP153 TP53BP2	8.82e-04	430	60	5	35044719
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	PHF3 PRRC2C DDX52 ANKRD52 NUP153 RAI1	9.07e-04	653	60	6	22586326
Pubmed	A census of human transcription factors: function, expression and evolution.	MLXIPL JUND HIVEP1 HOXC13 SREBF2 CERS6 CAMTA1	9.37e-04	908	60	7	19274049
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ATG7 CACNA2D2 SREBF2 FAM117B CERS6 RIMS1 CAMTA1 RAI1 NBPF1	9.73e-04	1489	60	9	28611215
Pubmed	Genetic risk profiling and prediction of disease course in Crohn's disease patients.	TNFRSF1B BSN	1.07e-03	28	60	2	19422935
Pubmed	The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing.	JUND PRRC2C	1.15e-03	29	60	2	17577209
Pubmed	Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.	MLXIPL SREBF2	1.15e-03	29	60	2	20167577
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	JUND PRRC2C UBA3 NUP153 RAI1	1.16e-03	457	60	5	32344865
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	DAGLB MED24 DDX52 HSPH1 SREBF2 CERS6 NUP153	1.16e-03	942	60	7	31073040
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	MED24 HIVEP1 PHF3 RAI1	1.20e-03	268	60	4	33640491
Pubmed	The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis.	HSPH1 HLTF	1.23e-03	30	60	2	36732658
Pubmed	The synaptic vesicle cycle.	RIMS1 BSN	1.32e-03	31	60	2	15217342
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	CACNA2D2 RIMS1 CAMTA1	1.43e-03	128	60	3	30995482
Pubmed	Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.	ATG7 BSN	1.58e-03	34	60	2	25915474
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	MLXIPL JUND PHF3 DDX52 HLTF NUP153 RAI1 NOL8	1.65e-03	1294	60	8	30804502
Cytoband	17q21.1	MED24 DDX52	3.14e-04	20	60	2	17q21.1
Cytoband	5q23.2	ZNF474 LOX	8.12e-04	32	60	2	5q23.2
Cytoband	12q13.3	HOXC13 ANKRD52	2.06e-03	51	60	2	12q13.3
Cytoband	3p21.3	CACNA2D2 ITGA9	2.74e-03	59	60	2	3p21.3
GeneFamily	Ubiquitin like modifier activating enzymes	ATG7 UBA3	2.46e-04	10	43	2	100
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#4_top-relative-expression-ranked_1000	FAM13C ADAM23 LOX RIMS1	9.38e-06	47	60	4	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k4
ToppCell	Substantia_nigra-Neuronal-Inhibitory\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CACNA2D2 CERS6 RIMS1 CAMTA1 BSN	5.20e-06	186	60	5	9d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PPP1R3A ADAM23 PXDNL PSD3 ITGA9	5.76e-06	190	60	5	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	JUND HSPH1 SREBF2 NUP153 TP53BP2	6.22e-06	193	60	5	dbf0fe496254320c894568c31e5f9ce63707d1b5
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	BOC JUND ZNF474 HSPH1	6.43e-05	160	60	4	21f7c0337fbd99e4a20650920d8302d7318bd25e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	HIVEP1 PHF3 HSPH1 FAM117B	7.59e-05	167	60	4	ced6ed9b412739c6ced622523347c10295edbf53
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MLXIPL AFF2 SREBF2 BSN	8.90e-05	174	60	4	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	10x3'2.3-week_12-13-Myeloid_macrophage-stroma-erythroid_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	BOC HIVEP1 LOX PSD3	9.93e-05	179	60	4	c17ae394b855f01f8ca1765c416fd8b34a96e60b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CHST15 CACNA2D2 AHR ITGA9	1.10e-04	184	60	4	7f6c8912677764d438ab0555faca344d74c2f483
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP1 PSD3 OSBPL10 CERS6	1.10e-04	184	60	4	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	JUND HIVEP1 HSPH1 OSBPL10	1.13e-04	185	60	4	e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D175\|Adult / Lineage, Cell type, age group and donor	SPTBN5 CHST15 PSD3 ITGA9	1.13e-04	185	60	4	ab5704b96f1d368911308797d10c7c52766ab134
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CERS6 RIMS1 CAMTA1 BSN	1.15e-04	186	60	4	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	APCDD1 LIN28B ADAM23 ITGA9	1.17e-04	187	60	4	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BOC FAM13C RIMS1 ITGA9	1.20e-04	188	60	4	293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	LIN28B ADAM23 OSBPL10 ITGA9	1.20e-04	188	60	4	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	JUND CHST15 AHR TNFRSF1B	1.22e-04	189	60	4	55aba1ebc012006a5db3ff9c92589cb3d9f7c68a
ToppCell	facs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC APCDD1 GRIK4 ITGA9	1.25e-04	190	60	4	c7bd087f36321cec61b98657433b4d19d135791f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC APCDD1 GRIK4 ITGA9	1.25e-04	190	60	4	834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	JUND PHF3 PRRC2C HSPH1	1.27e-04	191	60	4	1ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	JUND HSPH1 SREBF2 NUP153	1.30e-04	192	60	4	3f925a80b5e2b0577d573e88598a2984a5f6a789
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	HIVEP1 PHF3 PRRC2C HSPH1	1.33e-04	193	60	4	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	COVID-19_Convalescent-PLT_4\|COVID-19_Convalescent / Disease Group and Platelet Clusters	DDX52 AHR WHAMM UBA3	1.35e-04	194	60	4	ce1fad4e76a87f0c35e430ed1f2262395df882fd
ToppCell	facs-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BOC THBS3 PRRC2C ITGA9	1.38e-04	195	60	4	c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3A AFF2 PRRC2C LOX	1.38e-04	195	60	4	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	COPD-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	SHLD2 AHR RIMS1 ITGA9	1.41e-04	196	60	4	af96fb94886e9395f3e2cd0a293af29229d017fe
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CHST15 PSD3 GRIK4 CERS6	1.44e-04	197	60	4	b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	JUND PHF3 PRRC2C WHAMM	1.44e-04	197	60	4	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BOC MLXIPL APCDD1 LOX	1.44e-04	197	60	4	17344464fdcc5ba0c03959696b97c195f11e644c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CHST15 PSD3 GRIK4 CERS6	1.44e-04	197	60	4	6d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BOC MLXIPL APCDD1 LOX	1.44e-04	197	60	4	3bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BOC MLXIPL APCDD1 LOX	1.44e-04	197	60	4	5b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CHST15 PSD3 GRIK4 CERS6	1.44e-04	197	60	4	c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	JUND PHF3 PRRC2C WHAMM	1.46e-04	198	60	4	44417089b62056269cac38d3134ff209c05b7007
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	JUND PHF3 PRRC2C WHAMM	1.46e-04	198	60	4	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	Caecum-T_cell-Th1\|T_cell / Region, Cell class and subclass	JUND ADAM23 HSPH1 OSBPL10	1.49e-04	199	60	4	13a80e6d3cf9c831edbe0644545071153e35f82b
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	PHF3 PRRC2C HSPH1 CERS6	1.49e-04	199	60	4	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	BOC THBS3 FAM13C LOX	1.52e-04	200	60	4	64d2941689d7ca8af54f9ba21c5aeabf719084ef
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-OPC_related-Oligodendrocyte/OPC\|2m / Sample Type, Dataset, Time_group, and Cell type.	BOC APCDD1 LOX TP53BP2	1.52e-04	200	60	4	3c9a2f02294a9fb892b89e856291bd6423ffa0a9
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-OPC_related\|2m / Sample Type, Dataset, Time_group, and Cell type.	BOC APCDD1 LOX TP53BP2	1.52e-04	200	60	4	8e49e7e9b02d8411e4ffae1f5113a2c18f5bf179
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	BOC THBS3 FAM13C LOX	1.52e-04	200	60	4	76f3043cb88071256ff661885fe5a82a54f5b733
Disease	gout	SHLD2 MLXIPL THBS3 PXDNL PSD3	4.60e-05	196	59	5	EFO_0004274
Disease	Liver Cirrhosis	JUND LOX AHR TNFRSF1B	5.50e-05	103	59	4	C0023890
Disease	Fibrosis, Liver	JUND LOX AHR TNFRSF1B	5.93e-05	105	59	4	C0239946
Disease	gallstones	DAGLB MLXIPL LIN28B NUP153	6.62e-05	108	59	4	EFO_0004210
Disease	sporadic amyotrophic lateral sclerosis, survival time	PSD3 CAMTA1	1.09e-04	8	59	2	EFO_0000714, EFO_0001357
Disease	N-acetylphenylalanine measurement	ALMS1 C2orf78	2.14e-04	11	59	2	EFO_0800019
Disease	1-methylxanthine measurement	PSD3 AHR	2.14e-04	11	59	2	EFO_0021174
Disease	N-acetylglutamine measurement	ALMS1 PSD3	3.02e-04	13	59	2	EFO_0800017
Disease	coffee consumption, cups of coffee per day measurement	MLXIPL AHR	4.63e-04	16	59	2	EFO_0004330, EFO_0006782
Disease	coffee consumption measurement	MLXIPL CACNA2D2 AHR RAI1	4.89e-04	182	59	4	EFO_0006781
Disease	Moderate albuminuria	PRRC2C AHR CAMTA1	5.59e-04	80	59	3	HP_0012594
Disease	neuritic plaque measurement	PPP1R3A PXDNL OSBPL10 GRIK4 RIMS1	6.67e-04	349	59	5	EFO_0006798
Disease	waist-hip ratio	PPP1R3A MLXIPL JUND HOXC13 ATG7 APCDD1 ADAM23 RIMS1 ITGA9	6.93e-04	1226	59	9	EFO_0004343
Disease	colorectal cancer, hormone replacement therapy	PPP1R3A HIVEP1 CAMTA1	7.38e-04	88	59	3	EFO_0003961, MONDO_0005575
Disease	Obesity	APCDD1 AHR TNFRSF1B RAI1	7.64e-04	205	59	4	C0028754
Disease	small vessel stroke	ZNF474 ATG7 GRIK4	9.51e-04	96	59	3	EFO_1001504
Disease	type 2 diabetes mellitus (implicated_via_orthology)	PPP1R3A AFF2 ALMS1	1.23e-03	105	59	3	DOID:9352 (implicated_via_orthology)
Disease	bitter non-alcoholic beverage consumption measurement	MLXIPL AHR	1.88e-03	32	59	2	EFO_0010093
Disease	reaction time measurement	MLXIPL CHST15 FAM13C RIMS1 CAMTA1 RAI1	1.99e-03	658	59	6	EFO_0008393
Disease	triglyceride measurement, physical activity	MLXIPL PSD3	2.12e-03	34	59	2	EFO_0003940, EFO_0004530
Disease	complex trait	MLXIPL LIN28B PSD3 F13B	2.13e-03	271	59	4	EFO_0010578
Disease	Growth Disorders	AHR RAI1	2.37e-03	36	59	2	C0018273
Disease	hepatocyte growth factor-like protein measurement	CACNA2D2 BSN	2.64e-03	38	59	2	EFO_0008154
Disease	phospholipid measurement	MLXIPL PSD3 ITGA9	2.80e-03	140	59	3	EFO_0004639
Disease	cups of coffee per day measurement	MLXIPL AHR	2.92e-03	40	59	2	EFO_0006782
Disease	non-high density lipoprotein cholesterol measurement	MLXIPL THBS3 HIVEP1 PSD3 AHR RAI1	2.96e-03	713	59	6	EFO_0005689
Disease	rosacea severity measurement	AHR RIMS1 CAMTA1	3.21e-03	147	59	3	EFO_0009180
Disease	free cholesterol to total lipids in very small VLDL percentage	MLXIPL PSD3	3.37e-03	43	59	2	EFO_0022290

Protein segments in the cluster

Peptide	Gene	Start	Entry
CLQLPENQKHGLNPQ	AHR	741	P35869
PGVCGASQTHQKPQN	DDX52	56	Q9Y2R4
QAQLGQNPRIHCPAS	CAMTA1	1171	Q9Y6Y1
PPNLHKQDGYACNQN	ADAM23	581	O75077
TQIPNQQGHNLSLPC	C2orf78	191	A6NCI8
NRTHQDQPQKCGPNS	CACNA2D2	861	Q9NY47
QNHLVGIPKNSVPQN	AFF2	91	P51816
NKHHFPLPQGQDCVV	ALMS1	2981	Q8TCU4
GNPFTPLHCAVINNQ	ANKRD52	821	Q8NB46
GKPVIAAAQNQQQHP	TP53BP2	646	Q13625
CQPQTRAQKQPGHTN	RAI1	1516	Q7Z5J4
DKGCQTQQQPHSPQN	SMCP	96	P49901
KNNFGAEPPHQNGEC	HSPH1	831	Q92598
HVNSGCQLLPQHQVP	JUND	331	P17535
VANCPHKNVAQPPAS	LIN28B	161	Q6ZN17
KVCNQCGFNPNPHLT	BSN	196	Q9UPA5
QVNAPINCVCLHPNQ	MLST8	126	Q9BVC4
ENNENCKHPPVVMNG	F13B	391	P05160
EVTPCQHAKKANGPN	NOL8	626	Q76FK4
HGPCDSNQPHKNINI	NBPF1	486	Q3BBV0
NANPAHGNGTVQIPC	PPP1R3A	441	Q16821
ACKTPRNAENQPHQP	RIMS1	66	Q86UR5
NITAPQCHDGQQPVN	ITGA9	476	Q13797
KNINISCHAQGEPQP	PXDNL	526	A1KZ92
KQQGAGDLCPNHPVA	ATG7	516	O95352
KPQQHCPGELQQQSD	BOC	951	Q9BWV1
GNVQNVPHGSIPLCQ	CPLANE1	2151	Q9H799
NNQEPAQVVCHAPGS	DAGLB	251	Q8NCG7
GNHAAINQCQAPVPK	FAM117B	311	Q6P1L5
NNTPLHIAAQNNCPA	FEM1A	581	Q9BSK4
INAPGDNPAKVQNHC	C1RL	181	Q9NZP8
QPPLQNAKNHDHACI	APCDD1	251	Q8J025
KPCAIALNIQANGPQ	CERS6	61	Q6ZMG9
HNVNLQQKPCAYHPG	HOXC13	136	P31276
CALVHCAPPAAGQQQ	LOX	16	P28300
KPCICQVIQNEQPHA	HLTF	781	Q14527
QVIQNEQPHAKCPLC	HLTF	786	Q14527
PHPCAQGRCNLLVNQ	GRIK4	576	Q16099
AQDNPENVQCGHRPA	PRSS51	16	A0A1B0GVH4
IRVNQSQHCPQGAAP	OTOG	2071	Q6ZRI0
VPCHQAGAQEAQPLQ	PLAC1	176	Q9HBJ0
NCNNSVPGKEHPFDI	GPR108	226	Q9NPR9
HAPQQKSGENANIQP	MED24	391	O75448
IACGPPQAKLNGQQA	PRRC2C	221	Q9Y520
QPKHQPDICGKNFNT	SHLD2	151	Q86V20
SPKCQNCHGNIPVQV	WHAMM	606	Q8TF30
TPAHESPQNNAFKCQ	FAM13C	126	Q8NE31
CQQQLPATGVPITHQ	MLXIPL	731	Q9NP71
LQQSVHQAGQPSQKP	OSBPL10	296	Q9BXB5
CPGPQAHAVQQRQQA	SPTBN5	1906	Q9NRC6
LLPDGAHKQQVNCQG	CHST15	11	Q7LFX5
VPNCNVVPHFNKIQD	UBA3	136	Q8TBC4
FGHAKQLCPNLQAVP	REV1	526	Q9UBZ9
NPADPIAQVHQAFCK	SREBF2	791	Q12772
HSSQKQCHKPQQQAP	PHF3	621	Q92576
CHQGPIKPYQQGRQQ	NUP153	21	P49790
GHQDTKDNCPQLPNS	THBS3	631	P49746
QAGPNQAQLVFCPHC	ZNF474	276	Q6S9Z5
PHQICNVVAIPGNAS	TNFRSF1B	181	P20333
GEALPCHPQEQQGVQ	PSD3	81	Q9NYI0
VPKSNQHNQQLPGCS	HIVEP1	291	P15822
QNALGCNPSLPKHNV	HIVEP1	1061	P15822