Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

7.44e-09261176GO:0005248
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

1.22e-08141175GO:0031402
GeneOntologyMolecularFunctionsodium channel activity

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G

2.13e-08521177GO:0005272
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

3.78e-07261175GO:0031420
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC24A3 SLC24A4 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G

7.51e-071711179GO:0015081
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SLC24A3 SLC24A4 TRPM3 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G UNC80

5.61e-0634311711GO:0005261
GeneOntologyMolecularFunctionapolipoprotein A-I receptor activity

ABCA1 ABCA7

3.40e-0521172GO:0034188
GeneOntologyMolecularFunctionchannel activity

SLC24A3 SLC24A4 TRPM3 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G GSDMA UNC80

6.03e-0552511712GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SLC24A3 SLC24A4 TRPM3 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G GSDMA UNC80

6.14e-0552611712GO:0022803
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SLC24A3 SLC24A4 TRPM3 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G UNC80

8.17e-0545911711GO:0005216
GeneOntologyMolecularFunctionapolipoprotein receptor activity

ABCA1 ABCA7

1.02e-0431172GO:0030226
GeneOntologyMolecularFunctionrhodopsin kinase activity

GRK4 GRK1

1.02e-0431172GO:0050254
GeneOntologyMolecularFunctioncalcium, potassium:sodium antiporter activity

SLC24A3 SLC24A4

3.37e-0451172GO:0008273
GeneOntologyMolecularFunctionhelicase activity

ERCC6 DHX40 DDX56 SUPV3L1 DNA2 AQR

3.39e-041581176GO:0004386
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC24A3 SLC24A4 TRPM3 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G

4.12e-0446511710GO:0046873
GeneOntologyMolecularFunction3'-5' RNA helicase activity

SUPV3L1 AQR

5.03e-0461172GO:0034458
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA1 ABCA4 ABCA7

5.77e-04281173GO:0140326
GeneOntologyMolecularFunctionG protein-coupled receptor kinase activity

GRK4 GRK1

7.01e-0471172GO:0004703
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

ABCA1 OR2T33 CALCR GPR37 OR2T12 OR14C36 NPFFR1 ABCA7 BDKRB1 OR2T8 OR1N1 OR51E2 OR14K1 GPR61 OR52A4P LMBR1L SCN7A PLXNA1

8.80e-04135311718GO:0004888
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ABCA1 ABCA7

9.31e-0481172GO:0090554
GeneOntologyMolecularFunctionATP-dependent activity

ABCA1 ABCA4 ERCC6 DHX40 DDX56 ABCA7 DNAH14 DNAH1 SUPV3L1 DNA2 AQR

9.69e-0461411711GO:0140657
GeneOntologyMolecularFunctionRNA helicase activity

DHX40 DDX56 SUPV3L1 AQR

1.14e-03781174GO:0003724
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA1 ABCA4 ERCC6 DHX40 DDX56 ABCA7 SUPV3L1 DNA2 AQR

1.16e-034411179GO:0016887
GeneOntologyMolecularFunctionphosphatidylserine floppase activity

ABCA1 ABCA7

1.19e-0391172GO:0090556
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

DHX40 DDX56 SUPV3L1 AQR

1.26e-03801174GO:0008186
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCA1 ABCA4 SLC24A3 ABCA7 SLC24A4 TRPM3 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G GSDMA DISP1 UNC80

1.43e-03118011716GO:0022857
GeneOntologyMolecularFunctioncalcium:sodium antiporter activity

SLC24A3 SLC24A4

1.49e-03101172GO:0005432
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC24A3 SLC24A4 TRPM3 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G UNC80

1.81e-0366411711GO:0008324
GeneOntologyMolecularFunctionhistone H3K36 demethylase activity

KDM4A UTY

1.81e-03111172GO:0051864
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR2T33 CALCR GPR37 OR2T12 OR14C36 NPFFR1 BDKRB1 OR2T8 OR1N1 OR51E2 OR14K1 GPR61 OR52A4P

2.03e-0388411713GO:0004930
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

ABR PLEKHG7 DOCK10 DENND2C DENND6B HERC2

2.42e-032311176GO:0005085
GeneOntologyMolecularFunctioncalcium:monoatomic cation antiporter activity

SLC24A3 SLC24A4

2.55e-03131172GO:0015368
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA1 ABCA4 ABCA7

2.97e-03491173GO:0140359
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA1 ABCA4 ABCA7

3.33e-03511173GO:0140303
GeneOntologyMolecularFunctiontransporter activity

ABCA1 ABCA4 SLC24A3 ABCA7 SLC24A4 TRPM3 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G GSDMA DISP1 UNC80

3.48e-03128911716GO:0005215
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC24A3 SLC24A4 TRPM3 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G

3.81e-0362711710GO:0022890
GeneOntologyMolecularFunctionfloppase activity

ABCA1 ABCA7

3.87e-03161172GO:0140328
GeneOntologyMolecularFunctionolfactory receptor activity

OR2T33 OR2T12 OR14C36 OR2T8 OR1N1 OR51E2 OR14K1 OR52A4P

3.89e-034311178GO:0004984
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN1A SCN2A

4.37e-03171172GO:0099508
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH14 DNAH1

4.90e-03181172GO:0008569
GeneOntologyMolecularFunctionsolute:potassium antiporter activity

SLC24A3 SLC24A4

5.45e-03191172GO:0022821
GeneOntologyMolecularFunctionDNA helicase activity

ERCC6 SUPV3L1 DNA2

5.77e-03621173GO:0003678
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

ABCA1 ABCA7

6.04e-03201172GO:0008525
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A UTY

8.89e-07931157GO:0086003
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

1.26e-06621156GO:0086002
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN1A SCN2A SCN3A SCN8A SCN9A

1.62e-06361155GO:0086010
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC24A3 SLC24A4 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G

2.53e-062081159GO:0035725
GeneOntologyBiologicalProcesssensory perception

ABCA4 OR2T33 ESPNL OR2T12 OR14C36 LRIT3 GRK1 BBS10 OR2T8 OR1N1 OR51E2 OR14K1 OR52A4P SLC24A4 OTOGL SCN1A SCN8A SCN9A SCNN1G

7.15e-06107211519GO:0007600
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A UTY

7.17e-061271157GO:0070252
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

9.21e-06871156GO:0086001
GeneOntologyBiologicalProcesssodium ion transport

SLC24A3 SLC24A4 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G

2.40e-052751159GO:0006814
GeneOntologyBiologicalProcessactin filament-based movement

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A UTY

2.42e-051531157GO:0030048
GeneOntologyBiologicalProcessneuronal action potential

SCN1A SCN2A SCN3A SCN8A SCN9A

2.68e-05631155GO:0019228
GeneOntologyBiologicalProcessnerve development

LRIT3 SLC24A4 SCN1A SCN2A SCN8A PLXNA1

3.34e-051091156GO:0021675
GeneOntologyBiologicalProcesscardiac muscle contraction

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A UTY

4.23e-051671157GO:0060048
GeneOntologyBiologicalProcessdetection of stimulus

ABCA4 OR2T33 GRK4 OR2T12 OR14C36 GRK1 OR2T8 OR1N1 OR51E2 OR14K1 OR52A4P SLC24A4 SCN1A SCN9A

4.96e-0572211514GO:0051606
GeneOntologyBiologicalProcessphototransduction, visible light

ABCA4 GRK4 GRK1

1.80e-04201153GO:0007603
GeneOntologyBiologicalProcessstriated muscle contraction

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A UTY

2.17e-042171157GO:0006941
GeneOntologyBiologicalProcessphototransduction

ABCA4 GRK4 GRK1 SLC24A4

2.17e-04531154GO:0007602
GeneOntologyBiologicalProcesscirculatory system process

ABR SLC24A3 BDKRB1 OR51E2 PIK3C2A SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G UTY

2.26e-0473311513GO:0003013
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

ABCA1 CIB1 OR2T33 CALCR GPR37 GRK4 OR2T12 OR14C36 NPFFR1 BDKRB1 GRK1 OR2T8 OR1N1 OR51E2 OR14K1 GPR61 OR52A4P SLC24A4 USP33

2.50e-04139511519GO:0007186
GeneOntologyBiologicalProcessblood circulation

ABR BDKRB1 OR51E2 PIK3C2A SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G UTY

2.70e-0464811512GO:0008015
GeneOntologyBiologicalProcessmuscle contraction

NCF1 PIK3C2A SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A UTY

4.08e-044001159GO:0006936
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN1A SCN2A SCN3A SCN8A SCN9A

4.12e-041121155GO:0019226
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR2T33 OR2T12 OR14C36 OR2T8 OR1N1 OR51E2 OR14K1 OR52A4P SLC24A4 SCN1A SCN9A

4.13e-0458211511GO:0050906
GeneOntologyBiologicalProcessdetection of external stimulus

ABCA4 GRK4 GRK1 SLC24A4 SCN1A SCN9A

4.22e-041731156GO:0009581
GeneOntologyBiologicalProcessdetection of abiotic stimulus

ABCA4 GRK4 GRK1 SLC24A4 SCN1A SCN9A

4.49e-041751156GO:0009582
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G UNC80

3.15e-12291188GO:0034706
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

3.35e-10171186GO:0001518
GeneOntologyCellularComponentcation channel complex

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G UNC80

5.73e-052351188GO:0034703
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN2A SCN8A

1.86e-04201183GO:0033268
GeneOntologyCellularComponentphotoreceptor disc membrane

ABCA4 GRK4 GRK1

4.15e-04261183GO:0097381
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN2A SCN8A

5.76e-04291183GO:0043194
GeneOntologyCellularComponentphotoreceptor cell cilium

ABCA4 GRK4 GRK1 SLC24A4 IFT88

1.16e-031391185GO:0097733
GeneOntologyCellularComponentmonoatomic ion channel complex

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A SCNN1G UNC80

1.38e-033781188GO:0034702
HumanPhenoComplex febrile seizure

SCN1A SCN2A SCN8A SCN9A

5.00e-0616394HP:0011172
HumanPhenoPhotosensitive myoclonic seizure

SCN1A SCN2A SCN9A

2.26e-058393HP:0001327
HumanPhenoCyanotic episode

SCN1A SCN2A SCN9A

2.26e-058393HP:0200048
HumanPhenoFocal hemiclonic seizure

SCN1A SCN2A SCN8A SCN9A

3.31e-0525394HP:0006813
HumanPhenoSimple febrile seizure

SCN1A SCN2A SCN3A SCN8A

4.54e-0527394HP:0011171
HumanPhenoLimited neck range of motion

SCN1A SCN2A SCN9A

6.56e-0511393HP:0000466
HumanPhenoEpilepsia partialis continua

SCN1A SCN2A SCN9A

8.71e-0512393HP:0012847
HumanPhenoFocal automatism seizure

SCN1A SCN2A SCN8A

8.71e-0512393HP:0032898
HumanPhenoImpulsivity

FUZ SCN1A SCN2A SCN3A SCN8A SCN9A DISP1

1.11e-04149397HP:0100710
HumanPhenoGeneralized cerebral atrophy/hypoplasia

SCN1A SCN2A SCN9A

1.13e-0413393HP:0007058
HumanPhenoGeneralized clonic seizure

SCN1A SCN2A SCN8A SCN9A

1.15e-0434394HP:0011169
HumanPhenoPoor fine motor coordination

FOCAD SCN1A SCN2A SCN9A HERC2

1.59e-0469395HP:0007010
HumanPhenoFacial tics

SCN1A SCN2A SCN9A

1.77e-0415393HP:0011468
HumanPhenoPhotosensitive tonic-clonic seizure

SCN1A SCN2A SCN9A

1.77e-0415393HP:0007207
HumanPhenoDysgenesis of the hippocampus

SCN1A SCN2A SCN9A

2.17e-0416393HP:0025101
HumanPhenoFocal motor status epilepticus

SCN1A SCN2A SCN9A

2.62e-0417393HP:0032663
HumanPhenoAtypical absence status epilepticus

SCN1A SCN2A SCN9A

2.62e-0417393HP:0011151
HumanPhenoFocal clonic seizure

SCN1A SCN2A SCN8A SCN9A

2.66e-0442394HP:0002266
HumanPhenoChoreoathetosis

ERCC6 DDC TRPM3 SCN1A SCN2A SCN8A

2.98e-04123396HP:0001266
HumanPhenoVisually-induced seizure

SCN1A SCN2A SCN9A

3.13e-0418393HP:0020216
HumanPhenoGeneralized non-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A

3.13e-0418393HP:0032860
HumanPhenoElectronegative electroretinogram

ABCA4 LRIT3 GRK1

3.13e-0418393HP:0007984
HumanPhenoClonic seizure

SCN1A SCN2A SCN3A SCN8A SCN9A

3.38e-0481395HP:0020221
HumanPhenoDecreased CSF 5-hydroxyindolacetic acid concentration

ERCC6 DDC

3.39e-044392HP:0025455
HumanPhenoAbnormal amplitude of dark-adapted bright flash electroretinogram

ABCA4 LRIT3 GRK1

3.69e-0419393HP:0030478
HumanPhenoAbnormal dark-adapted electroretinogram

ABCA4 LRIT3 GRK1

3.69e-0419393HP:0030469
HumanPhenoAbnormal dark-adapted bright flash electroretinogram

ABCA4 LRIT3 GRK1

3.69e-0419393HP:0030470
HumanPhenoPoor motor coordination

FOCAD SCN1A SCN2A SCN9A HERC2

4.24e-0485395HP:0002275
HumanPhenoNon-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A

4.32e-0420393HP:0032671
HumanPhenoAbnormal hippocampus morphology

ABCA7 SCN1A SCN2A SCN9A

4.48e-0448394HP:0025100
HumanPhenoAbnormal morphology of the limbic system

ABCA7 SCN1A SCN2A SCN9A

4.85e-0449394HP:0007343
HumanPhenoTalipes valgus

SCN1A SCN2A SCN9A

5.02e-0421393HP:0004684
HumanPhenoNeonatal electro-clinical non-motor seizure

SCN2A SCN8A

5.63e-045392HP:0032812
HumanPhenoNeonatal seizure with electrographic correlate

SCN2A SCN8A

5.63e-045392HP:0032808
HumanPhenoNeonatal electro-clinical seizure

SCN2A SCN8A

5.63e-045392HP:0032809
HumanPhenoNeonatal electro-clinical seizure with behavior arrest

SCN2A SCN8A

5.63e-045392HP:0032823
HumanPhenoCongenital ptosis

ZFHX4 DNA2

5.63e-045392HP:0007970
HumanPhenoFocal head nodding automatism seizure

SCN2A SCN8A

5.63e-045392HP:0032906
HumanPhenoReflex seizure

SCN1A SCN2A SCN9A

5.78e-0422393HP:0020207
HumanPhenoTibial torsion

SCN1A SCN2A SCN9A

6.61e-0423393HP:0100694
HumanPhenoInfection-related seizure

SCN1A SCN2A SCN3A SCN8A SCN9A HERC2

7.20e-04145396HP:0032892
HumanPhenoSeizure precipitated by febrile infection

SCN1A SCN2A SCN3A SCN8A SCN9A HERC2

7.20e-04145396HP:0032894
HumanPhenoFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A SCN3A SCN8A SCN9A HERC2

7.20e-04145396HP:0002373
HumanPhenoNormal interictal EEG

SCN2A SCN8A

8.40e-046392HP:0002372
DomainNa_channel_asu

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

1.04e-11101166IPR001696
DomainNa_trans_assoc

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

1.04e-11101166IPR010526
DomainNa_trans_assoc

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

1.04e-11101166PF06512
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN8A SCN9A

5.06e-1161165PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN8A SCN9A

5.06e-1161165IPR024583
DomainChannel_four-helix_dom

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

1.41e-06571166IPR027359
Domain-

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

1.41e-065711661.20.120.350
DomainIon_trans_dom

TRPM3 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

7.07e-061141167IPR005821
DomainIon_trans

TRPM3 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

7.07e-061141167PF00520
DomainIQ

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

1.12e-05811166SM00015
DomainIQ_motif_EF-hand-BS

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

2.05e-05901166IPR000048
DomainABC_A

ABCA1 ABCA4 ABCA7

4.93e-05121163IPR026082
DomainIQ

SCN1A SCN2A SCN3A SCN8A SCN9A

2.85e-04931165PS50096
DomainTPR_8

DNAJC7 IFT88 TTC12 UTY

3.27e-04531164PF13181
DomainK/Na/Ca-exchanger

SLC24A3 SLC24A4

3.78e-0451162IPR004481
DomainClathrin_mu_CS

AP3M1 AP3M2

5.64e-0461162IPR018240
DomainCLAT_ADAPTOR_M_1

AP3M1 AP3M2

5.64e-0461162PS00990
DomainCLAT_ADAPTOR_M_2

AP3M1 AP3M2

5.64e-0461162PS00991
DomainCoronin

CORO1C CORO7

7.87e-0471162IPR015505
DomainGPCR_kinase

GRK4 GRK1

7.87e-0471162IPR000239
DomainTrimer_CC

CORO1C CORO7

7.87e-0471162IPR015049
DomainDUF1899

CORO1C CORO7

7.87e-0471162IPR015048
DomainDUF1899

CORO1C CORO7

7.87e-0471162SM01166
DomainTrimer_CC

CORO1C CORO7

7.87e-0471162PF08954
DomainDUF1899

CORO1C CORO7

7.87e-0471162PF08953
DomainIQ

SCN1A SCN3A SCN8A SCN9A

9.96e-04711164PF00612
Domain7tm_1

OR2T33 GPR37 OR2T12 OR14C36 NPFFR1 BDKRB1 OR2T8 OR1N1 OR51E2 OR14K1 GPR61 OR52A4P

1.03e-0367711612PF00001
DomainG_PROTEIN_RECEP_F1_1

OR2T33 GPR37 OR2T12 OR14C36 NPFFR1 BDKRB1 OR2T8 OR1N1 OR51E2 OR14K1 GPR61 OR52A4P

1.14e-0368511612PS00237
DomainG_PROTEIN_RECEP_F1_2

OR2T33 GPR37 OR2T12 OR14C36 NPFFR1 BDKRB1 OR2T8 OR1N1 OR51E2 OR14K1 GPR61 OR52A4P

1.23e-0369111612PS50262
DomainGPCR_Rhodpsn

OR2T33 GPR37 OR2T12 OR14C36 NPFFR1 BDKRB1 OR2T8 OR1N1 OR51E2 OR14K1 GPR61 OR52A4P

1.24e-0369211612IPR000276
DomainNaCa_Exmemb

SLC24A3 SLC24A4

1.34e-0391162IPR004837
DomainNa_Ca_ex

SLC24A3 SLC24A4

1.34e-0391162PF01699
DomainClathrin_mu

AP3M1 AP3M2

1.67e-03101162IPR001392
DomainAdap_comp_sub

AP3M1 AP3M2

2.03e-03111162PF00928
DomainABC_transporter_CS

ABCA1 ABCA4 ABCA7

2.25e-03421163IPR017871
Domain-

ABCA1 ABCA4 ERCC6 DHX40 CMPK2 DDX56 ABCA7 DNAH14 DNAH1 SUPV3L1 DNA2 AQR

2.33e-03746116123.40.50.300
DomainTPR_1

DNAJC7 IFT88 TTC12 UTY

2.39e-03901164PF00515
DomainTPR_1

DNAJC7 IFT88 TTC12 UTY

2.39e-03901164IPR001440
DomainClathrin_sm-chain_CS

AP3M1 AP3M2

2.42e-03121162IPR000804
DomainPX

SNX4 NCF1 PIK3C2A

2.57e-03441163SM00312
DomainMHD

AP3M1 AP3M2

2.85e-03131162PS51072
DomainMHD

AP3M1 AP3M2

2.85e-03131162IPR028565
DomainGPCR_Rhodpsn_7TM

OR2T33 GPR37 OR2T12 OR14C36 NPFFR1 BDKRB1 OR2T8 OR1N1 OR51E2 GPR61 OR52A4P

3.03e-0367011611IPR017452
DomainOlfact_rcpt

OR2T33 OR2T12 OR14C36 OR2T8 OR1N1 OR51E2 OR14K1 OR52A4P

3.16e-033931168IPR000725
DomainABC_tran

ABCA1 ABCA4 ABCA7

3.29e-03481163PF00005
DomainABC_TRANSPORTER_2

ABCA1 ABCA4 ABCA7

3.29e-03481163PS50893
DomainDynein_heavy_chain_D4_dom

DNAH14 DNAH1

3.31e-03141162IPR024317
DomainDynein_HC_stalk

DNAH14 DNAH1

3.31e-03141162IPR024743
DomainMT

DNAH14 DNAH1

3.31e-03141162PF12777
DomainAAA_8

DNAH14 DNAH1

3.31e-03141162PF12780
DomainABC_TRANSPORTER_1

ABCA1 ABCA4 ABCA7

3.49e-03491163PS00211
DomainPX

SNX4 NCF1 PIK3C2A

3.49e-03491163PF00787
DomainPX

SNX4 NCF1 PIK3C2A

3.70e-03501163PS50195
DomainABC_transporter-like

ABCA1 ABCA4 ABCA7

3.70e-03501163IPR003439
DomainDHC_fam

DNAH14 DNAH1

3.81e-03151162IPR026983
DomainDynein_heavy_dom

DNAH14 DNAH1

3.81e-03151162IPR004273
DomainDynein_heavy

DNAH14 DNAH1

3.81e-03151162PF03028
Domain-

SNX4 NCF1 PIK3C2A

3.91e-035111633.30.1520.10
DomainPhox

SNX4 NCF1 PIK3C2A

4.13e-03521163IPR001683
DomainAP_mu_sigma_su

AP3M1 AP3M2

4.34e-03161162IPR022775
DomainClat_adaptor_s

AP3M1 AP3M2

4.34e-03161162PF01217
DomainHelicase_C

ERCC6 DHX40 DDX56 SUPV3L1

4.46e-031071164PF00271
DomainHELICc

ERCC6 DHX40 DDX56 SUPV3L1

4.46e-031071164SM00490
DomainHelicase_C

ERCC6 DHX40 DDX56 SUPV3L1

4.61e-031081164IPR001650
DomainHELICASE_CTER

ERCC6 DHX40 DDX56 SUPV3L1

4.76e-031091164PS51194
DomainHELICASE_ATP_BIND_1

ERCC6 DHX40 DDX56 SUPV3L1

4.76e-031091164PS51192
DomainAGC-kinase_C

CDC42BPA GRK4 GRK1

5.09e-03561163IPR000961
DomainAGC_KINASE_CTER

CDC42BPA GRK4 GRK1

5.09e-03561163PS51285
DomainS_TK_X

CDC42BPA GRK4 GRK1

5.09e-03561163SM00133
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

3.02e-0831876M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

3.70e-0832876M27455
PathwayREACTOME_SENSORY_PERCEPTION

ABCA4 OR2T33 GRK4 ESPNL OR2T12 OR14C36 GRK1 OR2T8 OR1N1 OR51E2 OR14K1 OTOGL SCN2A SCN3A SCN9A SCNN1G

1.46e-066368716M41834
PathwayWP_DRAVET_SYNDROME

SCN1A SCN2A SCN3A SCN8A

2.47e-0528874M45519
PathwayREACTOME_L1CAM_INTERACTIONS

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

1.01e-04121876M872
PathwayREACTOME_CARDIAC_CONDUCTION

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

1.50e-04130876M27454
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

SCN2A SCN3A SCN9A SCNN1G

1.97e-0447874M42524
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN2A SCN3A SCN8A SCN9A SCNN1G

2.38e-1213119615123669
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A SCN3A SCN8A SCN9A

2.58e-126119523652591
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN2A SCN3A SCN8A SCN9A

5.37e-119119516382098
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN3A SCN8A

1.30e-104119417537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN3A SCN8A

1.30e-104119435031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN3A SCN8A

1.30e-104119429578003
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A SCN3A SCN9A

6.50e-10511948812438
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN3A SCN8A

1.62e-089119415746173
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN3A SCN9A

3.91e-083119319284629
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A SCN3A

3.91e-083119312610651
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN3A SCN9A

3.91e-083119333895391
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A SCN3A

3.91e-083119323859570
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A SCN3A

3.91e-083119318784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A SCN3A

3.91e-083119317544618
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A SCN8A

3.91e-083119332845893
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A SCN8A

3.91e-083119328518218
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A SCN8A

3.91e-083119317928448
Pubmed

Differential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutants.

ABCA1 ABCA4 ABCA7

3.91e-083119324097981
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A SCN3A

3.91e-083119314973256
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN3A SCN8A

6.31e-0812119430175250
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A SCN8A

1.56e-074119321156207
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A SCN3A

1.56e-074119335801810
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A SCN3A

1.56e-07411938974318
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

SCN1A SCN2A SCN3A SCN7A

1.73e-071511949726281
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN2A SCN3A

3.89e-07511931679748
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN3A SCN8A SCN9A

3.89e-075119322875929
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN3A SCN8A

3.89e-075119317724025
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A SCN3A

3.89e-075119324337656
Pubmed

Integrative predictive model of coronary artery calcification in atherosclerosis.

ABCA1 ABCA4 ERCC6 CYP2E1 GRK4 NCF1 SCNN1G TNFAIP3

1.31e-06229119819948975
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN2A SCN8A

1.35e-067119325818041
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN2A SCN3A

8.40e-061211938169823
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

SCN1A SCN3A SCN7A SCN8A SCN9A SCNN1G

8.76e-06139119616985003
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

1.16e-052119229649454
Pubmed

Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.

SCN2A SCN3A

1.16e-052119220346423
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

1.16e-052119237901435
Pubmed

Effects of SNPs (CYP1B1*2 G355T, CYP1B1*3 C4326G, and CYP2E1*5 G-1293C), smoking, and drinking on susceptibility to laryngeal cancer among Han Chinese.

CYP1B1 CYP2E1

1.16e-052119225299224
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

1.16e-052119226410685
Pubmed

ATP-binding cassette transporter 1 (ABCA1) deficiency decreases platelet reactivity and reduces thromboxane A2 production independently of hematopoietic ABCA1.

ABCA1 ABCA7

1.16e-052119226749169
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

1.16e-052119210827969
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

1.16e-052119219694741
Pubmed

Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.

SCN2A SCN8A

1.16e-052119235348308
Pubmed

Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.

SCN2A SCN3A

1.16e-052119211245985
Pubmed

Lysophosphatidylcholine export by human ABCA7.

ABCA1 ABCA7

1.16e-052119228373057
Pubmed

Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.

SCN2A SCN8A

1.16e-052119215760941
Pubmed

Preferential incorporation of shorter and less unsaturated acyl phospholipids into high density lipoprotein-like particles in the ABCA1- and ABCA7-mediated biogenesis with apoA-I.

ABCA1 ABCA7

1.16e-052119225665932
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

1.16e-05211921317301
Pubmed

Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment.

ABCA1 SCN1A

1.16e-052119217322896
Pubmed

Effect of BI-1 on insulin resistance through regulation of CYP2E1.

CYP2E1 TMBIM6

1.16e-052119227576594
Pubmed

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.

SCN2A SCN3A

1.16e-052119223016767
Pubmed

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

SCN2A SCN3A

1.16e-052119227153334
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

1.16e-052119233096315
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

1.16e-052119224990319
Pubmed

Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.

SCN3A SCN9A

1.16e-052119225172946
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

1.16e-052119231439038
Pubmed

Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein.

ABCA1 ABCA7

1.16e-052119214570867
Pubmed

The IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosis.

CYP2E1 PHLDA2

1.16e-05211929328465
Pubmed

Sodium channel expression within chronic multiple sclerosis plaques.

SCN2A SCN8A

1.16e-052119217805013
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

1.16e-052119226311622
Pubmed

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

SCN1A SCN8A

1.16e-052119233411788
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

1.16e-052119231943325
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

1.16e-052119215249644
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

1.16e-052119227690330
Pubmed

Sodium channel slow inactivation interferes with open channel block.

SCN8A SCN9A

1.16e-052119227174182
Pubmed

Heterogeneity of high density lipoprotein generated by ABCA1 and ABCA7.

ABCA1 ABCA7

1.16e-052119215930518
Pubmed

The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.

SCN1A SCN2A

1.16e-052119221377452
Pubmed

Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a.

SCN2A SCN8A

1.16e-052119218601978
Pubmed

Bax inhibitor-1 regulates the expression of P450 2E1 through enhanced lysosome activity.

CYP2E1 TMBIM6

1.16e-052119222230367
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

1.16e-052119223965409
Pubmed

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.

SCN2A SCN8A

1.16e-052119219465131
Pubmed

Bax inhibitor 1 regulates ER-stress-induced ROS accumulation through the regulation of cytochrome P450 2E1.

CYP2E1 TMBIM6

1.16e-052119219339548
Pubmed

Direct amplification of a single dissected chromosomal segment by polymerase chain reaction: a human brain sodium channel gene is on chromosome 2q22-q23.

SCN2A SCN7A

1.16e-05211921846440
Pubmed

Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.

SCN1A SCN8A

1.16e-052119237665666
Pubmed

The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.

SCN1A SCN8A

1.16e-052119217881658
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

1.16e-052119230693367
Pubmed

Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.

SCN2A SCN8A

1.16e-052119223735284
Pubmed

Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.

SCN1A SCN2A

3.47e-053119228784306
Pubmed

Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.

SCN1A SCN2A

3.47e-053119232185219
Pubmed

A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects.

LRIT3 GRK1

3.47e-053119226427409
Pubmed

Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.

SCN1A SCN2A

3.47e-053119232005694
Pubmed

Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia.

SCN3A SCN9A

3.47e-053119219699781
Pubmed

FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth.

FRMD8 FRMD8P1

3.47e-053119237527040
Pubmed

Genetic, physical, and transcript map of the fld region on mouse chromosome 12.

LPIN1 GREB1

3.47e-053119210644441
Pubmed

Where is the spike generator of the cochlear nerve? Voltage-gated sodium channels in the mouse cochlea.

SCN2A SCN8A

3.47e-053119216033895
Pubmed

Role of sodium channel subtype in action potential generation by neocortical pyramidal neurons.

SCN2A SCN8A

3.47e-053119229991598
Pubmed

GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.

SCN1A SCN3A

3.47e-053119227816501
Pubmed

SNX4 in complex with clathrin and dynein: implications for endosome movement.

SNX4 DNAH1

3.47e-053119219529763
Pubmed

Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.

SCN1A SCN8A

3.47e-053119224704313
Pubmed

Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.

SCN1A SCN2A

3.47e-053119219270815
Pubmed

Genotypic variation in CYP2E1, GCKR, and PNPLA3 among nonalcoholic steatohepatitis patients of Turkish origin.

CYP2E1 GCKR

3.47e-053119239042259
Pubmed

Identification of functional voltage-gated Na(+) channels in cultured human pulmonary artery smooth muscle cells.

SCN2A SCN3A

3.47e-053119216052353
Pubmed

ATP-binding cassette transporters ABCA1, ABCA7, and ABCG1 in mouse spermatozoa.

ABCA1 ABCA7

3.47e-053119218793613
Pubmed

Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.

SCN1A SCN2A

3.47e-053119225155934
Pubmed

The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels.

SCN1A SCN8A

3.47e-053119228117367
Pubmed

Effects of deletion of macrophage ABCA7 on lipid metabolism and the development of atherosclerosis in the presence and absence of ABCA1.

ABCA1 ABCA7

3.47e-053119222403608
Pubmed

NudC-like protein 2 restrains centriole amplification by stabilizing HERC2.

HERC2 USP33

3.47e-053119231427565
Pubmed

Degradation of the deubiquitinating enzyme USP33 is mediated by p97 and the ubiquitin ligase HERC2.

HERC2 USP33

3.47e-053119224855649
Pubmed

CYP2E1 overexpression up-regulates both non-specific delta-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1.

CYP2E1 ALAD

3.47e-053119212469218
Pubmed

The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth.

FRMD8 FRMD8P1

3.47e-053119236720499
Pubmed

Experimental and computational evidence that Calpain-10 binds to the carboxy terminus of NaV1.2 and NaV1.6.

SCN2A SCN8A

3.47e-053119238514708
Pubmed

Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.

SCN1A SCN8A

3.47e-053119226182346
CytobandEnsembl 112 genes in cytogenetic band chr2q24

CERS6 SCN1A SCN2A SCN3A SCN7A SCN9A

1.07e-061271196chr2q24
Cytoband2q24.3

CERS6 SCN1A SCN2A

9.28e-061611932q24.3
Cytoband1q44

OR2T33 OR2T12 OR14C36 OR2T8 OR14K1

1.06e-0511011951q44
CytobandEnsembl 112 genes in cytogenetic band chr1q44

OR2T33 OR2T12 OR14C36 OR2T8 OR14K1

2.21e-051281195chr1q44
Cytoband2q24

SCN3A SCN9A

3.61e-041111922q24
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN2A SCN3A SCN8A SCN9A

1.98e-1098151203
GeneFamilyATP binding cassette subfamily A

ABCA1 ABCA4 ABCA7

3.04e-0514813805
GeneFamilyWD repeat domain containing|Coronins

CORO1C CORO7

4.10e-047812495
GeneFamilyOlfactory receptors, family 14

OR14C36 OR14K1

4.10e-047812163
GeneFamilyUPF1 like RNA helicases

DNA2 AQR

1.06e-03118121169
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

DNAJC7 IFT88 TTC12 UTY

1.77e-03115814769
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ABR PLEKHG7 DOCK10 PHLDA2 CADPS2

2.32e-03206815682
GeneFamilyDyneins, axonemal

DNAH14 DNAH1

2.58e-0317812536
GeneFamilyPHD finger proteins|Lysine demethylases

KDM4A UTY

5.13e-0324812485
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND2C DENND6B

5.56e-0325812504
CoexpressionHOEBEKE_LYMPHOID_STEM_CELL_UP

ABCA1 SLC24A3 LPIN1 TRIM33 SCN3A TNFAIP3

5.18e-06971186M14698
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 DNAH1 ZFHX4 TRPM3 OTOGL SCN2A SCN9A UNC80

3.58e-0818411982cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 DNAH1 ZFHX4 TRPM3 OTOGL SCN2A SCN9A UNC80

3.58e-081841198ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 DNAH1 ZFHX4 TRPM3 OTOGL SCN2A SCN9A UNC80

3.58e-0818411982b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

OR2T33 LRCH1 ITPKB SCN2A SCN3A SCN7A CADPS2

5.40e-071791197666072c0e8448dbaec1683d18368ec2502453f90
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CERS6 FOCAD SCN1A SCN2A SCN3A SCN8A UNC80

1.06e-061981197c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CERS6 FOCAD SCN1A SCN2A SCN3A SCN8A UNC80

1.06e-0619811976d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CERS6 FOCAD SCN1A SCN2A SCN3A SCN8A UNC80

1.06e-0619811974ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Mast_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA1 NCF1 DOCK10 SLC24A3 TNFAIP3 TDRD6

4.75e-061611196c54010d88f1ecb6e0235bb66084876a4d5bf1ecd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

OR2T8 TRPM3 SCN2A SCN3A SCN7A CADPS2

6.28e-0616911960332f539a2f7d6dcd081a5d2f567290721f5a329
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

OR2T8 TRPM3 SCN2A SCN3A SCNN1G CADPS2

9.00e-061801196788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLEKHG7 SLC24A4 TRPM3 SCN7A SCN9A CADPS2

1.05e-05185119610da5c2a92bfb3248d3f6f94a0933996326cf590
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALCR SLC24A3 LRCH1 ITPKB SCN2A SCN3A

1.15e-051881196bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALCR SLC24A3 LRCH1 ITPKB SCN2A SCN3A

1.15e-051881196eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMBIM6 TRPM3 SCN2A SCN3A SCNN1G CADPS2

1.30e-0519211960bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell(5)_Fibroblasts-(5)_Fibroblast-J_(Lipofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

CYP1B1 ETV7 PHLDA2 BDKRB1 SCN9A TNFAIP3

1.38e-051941196784b15119c91ace33d34bfb3d68c182566a3e9a8
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

USP18 ABCA1 ETV7 CMPK2 PHLDA2 TNFAIP3

1.42e-0519511961992a1673b7213e25f3c76ac77da35c57daceddd
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CYP1B1 DNAH14 OTOGL VNN1 TNFAIP3 UNC80

1.42e-051951196d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CYP1B1 DNAH14 OTOGL VNN1 TNFAIP3 UNC80

1.42e-05195119619853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_4|COVID-19_Severe / Disease condition and Cell class

USP18 ABCA1 ETV7 CMPK2 PHLDA2 TNFAIP3

1.42e-051951196787ea9f38ad8e2a836222ca97f4d927f7e79517d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CERS6 FOCAD SCN2A SCN3A SCN8A UNC80

1.46e-051961196676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellSevere_COVID-19|World / Disease group,lineage and cell class (2021.01.30)

CYP1B1 USP18 ETV7 CMPK2 PHLDA2 TNFAIP3

1.55e-05198119609fd456077bb3a657ad3b10c6cfe799b7266456a
ToppCellBAL-Severe|BAL / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CYP1B1 USP18 ETV7 CMPK2 PHLDA2 TNFAIP3

1.55e-051981196454aee3f4fe6d0beeccc55200b4495f4f9b44feb
ToppCellBAL-Severe|BAL / Location, Disease Group, Cell group, Cell class (2021.03.09)

CYP1B1 USP18 ETV7 CMPK2 PHLDA2 TNFAIP3

1.55e-051981196687f69c16343227854c882b4a0f3930ce534a3d2
ToppCellSevere|World / Condition, Lineage, Cell class and cell subclass

CYP1B1 USP18 NCF1 CMPK2 PHLDA2 TNFAIP3

1.59e-051991196a8b87f4f504a3b0ad6013277f0c9f543db3ef1fb
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

SLC24A3 SCN1A SCN2A SCN3A SCN9A UNC80

1.64e-052001196f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

SLC24A3 SCN1A SCN2A SCN3A SCN9A UNC80

1.64e-052001196cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

CERS6 FOCAD SCN2A SCN3A SCN8A UNC80

1.64e-05200119648d801219bc771d6c7e151dc88ca4c179988de85
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

SLC24A3 SCN1A SCN2A SCN3A SCN9A UNC80

1.64e-052001196c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

SLC24A3 SCN1A SCN2A SCN3A SCN9A UNC80

1.64e-0520011964fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

SLC24A3 SCN1A SCN2A SCN3A SCN9A UNC80

1.64e-052001196310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

SLC24A3 SCN1A SCN2A SCN3A SCN9A UNC80

1.64e-052001196961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN7A SCNN1G CADPS2

4.13e-051431195990844ca674d30b2924c74b45bed4fdfb8463fa7
ToppCelldroplet-Heart-4Chambers-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1B1 FOXR1 ERCC6 ESPNL UNC80

5.02e-05149119538890ddde0979977c8350f01497f1245ab51641a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A SCNN1G CADPS2

5.52e-051521195eee86b508b8f140ea44e21d8c04c409a7b689e39
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 ITPKB TRPM3 OSGEPL1 GSDMA

6.06e-051551195441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CALCR SLC24A3 LRCH1 ITPKB SCN2A

7.04e-0516011958bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CALCR SLC24A3 LRCH1 ITPKB SCN2A

7.04e-0516011952d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A SCNN1G CADPS2

7.46e-051621195285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A SCNN1G CADPS2

7.91e-0516411956fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHLDA2 DDC SUPV3L1 SPIDR CADPS2

8.14e-0516511957c771f22b58989572c939ed127e637ec28dc0dca
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXR1 SUPV3L1 ALAD TNFAIP3 AQR

8.61e-051671195e0f2509e86302eca8352821bce12597f6c51fc24
ToppCellfacs-Lung-EPCAM-24m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXR1 SUPV3L1 ALAD TNFAIP3 AQR

8.61e-051671195b25646b6653cd8814dbeae4c74ce899ede105200
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH1 OTOGL SCN3A SCN9A UNC80

9.11e-05169119512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALCR SLC24A3 LRCH1 ITPKB SCN2A

1.02e-0417311954bc6d93716f093b460c8b047199db8cab5fea720
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHLDA2 OR1N1 OR51E2 SLC24A4 CADPS2

1.07e-0417511953f233a7e19f594e0343f02286299cc42c711994c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHLDA2 OR1N1 OR51E2 SLC24A4 CADPS2

1.07e-04175119523acfbcc1eb5a066195a9fde20aa51b7303a81af
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERCC6 PIK3C2A SCN7A ZMYM6 USP33

1.07e-041751195bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A SCNN1G CADPS2

1.13e-041771195f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CENPN LRRC43 LRCH1 ABCA7 DNAH1

1.22e-04180119562511d76d24b836839c3dcc2bf30485ffe9401e2
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages|bone_marrow / Manually curated celltypes from each tissue

ABCA1 CDC42BPA CORO1C PHLDA2 BBS10

1.22e-041801195daf69a548ed7c6f285a6adcff00f99aa22f9d6a5
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHLDA2 OR51E2 SLC24A4 TRPM3 CADPS2

1.22e-0418011955391d23817f5cc88a0871ddb98968897c839f464
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

DDC SCN2A SCN3A SCN8A UNC80

1.29e-04182119557bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA1 CORO1C NCF1 GSDMA ADPGK

1.32e-041831195103c4c4595d8daa677679fd2fa1e99cd398e56dd
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A SCNN1G CADPS2

1.32e-041831195b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A SCNN1G CADPS2

1.32e-041831195d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRCH1 ITPKB SCN2A SCN3A CADPS2

1.32e-0418311952e831a4d99c6f983793df71c0994124c943c6da9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMBIM6 SCN2A SCN3A SCNN1G CADPS2

1.36e-0418411959690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

CYP1B1 ABCA1 ZFHX4 SCN7A GREB1

1.36e-04184119567164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK10 SLC24A3 NPFFR1 SLC24A4 PRR11

1.43e-041861195a558fd00053e7dd6216b01dc8e650c30cee451f1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A SCNN1G CADPS2

1.43e-04186119508632045d499e61dd96ff29a5a9a208afe58dc58
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK10 SLC24A3 NPFFR1 SLC24A4 PRR11

1.43e-04186119575b1f342be5d6dbe0e7acd924a0ca75964f6bab0
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK10 SLC24A3 NPFFR1 SLC24A4 PRR11

1.43e-0418611950c3d195077de7b4c354c127a26116438aef29244
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DDC SCN2A SCN3A SCN8A UNC80

1.43e-041861195b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A SCNN1G CADPS2

1.46e-041871195f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A SCNN1G CADPS2

1.46e-0418711952d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A SCNN1G CADPS2

1.46e-041871195e3095455d2f255854f339f6b05fa87852af0700f
ToppCellcritical-Epithelial-IRC-IFNG_responsive_cell|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

USP18 NCF1 ETV7 CMPK2 PHLDA2

1.50e-041881195023f6e34c2db8657d25e70a97b7b9d45166c13ad
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DDC SCN2A SCN3A SCN8A UNC80

1.50e-041881195c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A SCNN1G CADPS2

1.54e-0418911953a295c215b5c18e7c673f92b7af5be523421682c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRCH1 ITPKB SCN2A SCN3A SCN7A

1.54e-041891195975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell5'-Adult-Distal_Rectal-Hematopoietic-Myeloid-LYVE1+_Macrophage|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRK4 CMPK2 FAM120C SCN8A SCN9A

1.54e-0418911959e3c083174a64ea78648c6d48498fc4e721b569f
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-classical_monocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CYP1B1 NCF1 CMPK2 VNN1 UTY

1.54e-041891195cce6602ad68c177985a5e43cfb2776d615cfbca0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRCH1 ITPKB SCN2A SCN3A SCN7A

1.54e-0418911957eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell5'-Adult-Distal_Rectal-Hematopoietic-Myeloid|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRK4 CMPK2 FAM120C SCN8A SCN9A

1.54e-0418911956e19bfa52406ebe095daa99f958ec4d596ce6e39
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1A SCN2A SCN8A CADPS2 UNC80

1.54e-041891195f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellNeuroendocrine-neuroendo-2-Calca|World / Class top

DDC SCN3A SCN8A SCN9A UNC80

1.54e-0418911956baa9a74560121cc008bb8fa9b2b7a335b3aeee0
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DDC OR51E2 SCN2A SCN3A UNC80

1.58e-04190119540d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DDC OR51E2 SCN2A SCN3A UNC80

1.58e-041901195f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DDC OR51E2 SCN2A SCN3A UNC80

1.58e-041901195a9a705455019e28d655636de73b07540798f82e6
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

CYP1B1 USP18 ETV7 CMPK2 MOB3C

1.62e-0419111952da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A SCNN1G CADPS2

1.62e-04191119596b78b4e819ea6052334bfcbc7abbf35897df885
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 DDC ITPKB TRPM3 UNC80

1.65e-0419211955b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

MON2 DOCK10 AP3M2 TNFAIP3 UTY

1.65e-04192119547646d7e4990be85072987f92bf18d52f8da752e
ToppCellControl-Myeloid-TRAM2|Myeloid / Condition, Lineage and Cell class

ABCA1 NCF1 ETV7 SCN8A TNFAIP3

1.65e-041921195571fd71dad361a8b6c1bf9ad7184a89b3fbec667
ToppCellNeuroendocrine|World / Class top

DDC SCN3A SCN8A SCN9A UNC80

1.65e-0419211950199da3ef9ddb6673e9aa41f346f374838aec182
ToppCellPosterior_cortex-Neuronal|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CERS6 GPR61 SCN2A SCN8A UNC80

1.70e-041931195b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1A SCN2A SCN8A CADPS2 UNC80

1.70e-0419311955fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A SCNN1G CADPS2

1.74e-041941195be869e186386d03ebb670971dd24fa656b4b0edf
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CENPN CERS6 GSTCD SPIDR ADPGK

1.74e-0419411950e9830ad070c47acaa952400bf2a3ddbff664a2f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A SCNN1G CADPS2

1.74e-0419411954d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCelldroplet-Lung-LUNG-1m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABR DOCK10 TMBIM6 LPIN1 TNFAIP3

1.74e-041941195621e0e8fe77ff0be83ea9287ce46e97c47e2b3b9
ToppCellControl-Myeloid-TRAM2|Control / Condition, Lineage and Cell class

ABCA1 NCF1 ETV7 SCN8A TNFAIP3

1.74e-041941195d951dd1274d3ff1ac30671ec4153a4a8bc97b53f
ToppCelldroplet-Lung-1m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABR DOCK10 TMBIM6 LPIN1 TNFAIP3

1.74e-041941195d16ab5f0cfe73afe6c551fd3123d14784a082f56
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN7A SCNN1G CADPS2

1.78e-0419511953f517c6fc372bdcaf45b3af373414f13cbebd4ba
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FOXR1 DDC OR51E2 SCN3A UNC80

1.82e-04196119595544097577f20ed7f4144bd940471cde0617554
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PHLDA2 TRPM3 SCN2A SCNN1G CADPS2

1.82e-041961195142fd80ff74979cc2f9088fc3fcbfed374afb973
ToppCellBronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macro_interstitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

USP18 NCF1 ETV7 CMPK2 CERS6

1.86e-0419711951a30747a2188a890f58d831030328986b3a4356d
ToppCell(5)_Dendritic_cell-(54)_pDC|(5)_Dendritic_cell / shred on Cell_type and subtype

CAMKK1 CORO1C FUZ LPIN1 SCN9A

1.91e-041981195fc6c6b60dddd7f2f997af0f87fae33f1c23f34a8
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SCN2A SCN3A SCN8A GREB1 UNC80

1.91e-0419811958f25e8dff42bad8e779ca618bdb1cb1610667962
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOCAD SCN1A SCN2A SCN8A UNC80

1.91e-0419811958ab40fae14fe02e39bc8c8da187a5cd60c787643
Drugbenzocaine

SCN2A SCN3A SCN7A SCN9A SCNN1G

1.26e-06371175CID000002337
DrugZonisamide

SCN1A SCN2A SCN3A SCN9A

1.50e-06171174DB00909
Drugdihydrochloride

BDKRB1 TRPM3 SCN3A SCN7A SCN9A SCNN1G ALAD TNFAIP3

1.70e-061591178CID000070978
Drugdiprafenone

SCN3A SCN7A SCN9A SCNN1G

2.42e-06191174CID000071249
DrugAPETx1, Anthopleura elegantissima

SCN2A SCN3A SCN8A

2.62e-0661173ctd:C475726
Drugpilsicainide

CIB1 SCN3A SCN7A SCN9A SCNN1G

3.81e-06461175CID000004820
DrugSodium

BDKRB1 SCN2A SCN3A SCN8A SCN9A SCNN1G

4.75e-06841176ctd:D012964
Drug2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

SCN2A SCN3A SCN8A

7.27e-0681173ctd:C489827
DrugAC1NT1AF

SCN3A SCN7A SCN9A SCNN1G

7.71e-06251174CID005322157
DrugEvoxine [522-11-2]; Down 200; 11.6uM; PC3; HT_HG-U133A

ABR GPR37 NPFFR1 ABCA7 BDKRB1 LPIN1 SCN8A TNFAIP3

8.62e-0619811783681_DN
DrugICI 182,780; Down 200; 0.01uM; PC3; HT_HG-U133A

CYP2E1 GPR37 ABCA7 ITPKB TRIM33 FAM120C TNFAIP3 PLXNA1

8.62e-0619811781238_DN
DrugPirmenolum

SCN3A SCN7A SCN9A SCNN1G

9.07e-06261174CID000004853
DrugPbTx-1

SCN3A SCN7A SCN9A SCNN1G

1.06e-05271174CID006437089
DrugAC1L1MOZ

SCN3A SCN7A SCN9A SCNN1G

1.06e-05271174CID000031958
Drugnefopam

SCN3A SCN7A SCN9A SCNN1G

1.06e-05271174CID000004450
Drugpropafenone

CYP1B1 CYP2E1 SCN3A SCN7A SCN9A SCNN1G

1.16e-05981176CID000004932
Drugparaben

SCN3A SCN7A SCN9A SCNN1G

1.23e-05281174CID000007175
Drugtocainide

SCN3A SCN7A SCN9A SCNN1G

1.64e-05301174CID000038945
Drugzonisamide

CYP2E1 SCN3A SCN7A SCN9A SCNN1G

1.68e-05621175CID000005734
Druglidocaine

CYP2E1 PIK3C2A SCN3A SCN7A SCN9A SCNN1G TNFAIP3

1.93e-051601177CID000003676
Drugsaxitoxin

SCN2A SCN3A SCN7A SCN9A SCNN1G

2.12e-05651175CID000037165
DrugNSC93767

SCN3A SCN7A SCN9A SCNN1G

2.13e-05321174CID000005658
Drugdisopyramide

SCN3A SCN7A SCN9A SCNN1G TNFAIP3

2.29e-05661175CID000003114
Drugdnacin B1

GSTCD CDC25B

2.62e-0521172CID003086066
Drug5-hydroxypropafenone

SCN3A SCN7A SCN9A SCNN1G

2.73e-05341174CID000107927
Drugaprindine

SCN3A SCN7A SCN9A SCNN1G

4.27e-05381174CID000002218
DrugWithaferin A [5119-48-2]; Down 200; 1uM; MCF7; HT_HG-U133A

CYP1B1 GPR37 ITPKB FAM120C GREB1 TNFAIP3 SPIDR

5.05e-0518611773902_DN
DrugTetrodotoxin

SCN2A SCN3A SCN8A SCN9A

5.25e-05401174ctd:D013779
DrugS-ropivacaine

SCN3A SCN7A SCN9A SCNN1G

5.25e-05401174CID000071273
Drugbupropion

CYP2E1 SCN3A SCN7A SCN9A SCNN1G

6.17e-05811175CID000000444
DrugPropafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; MCF7; HT_HG-U133A

SLC24A3 GCKR ITPKB LPIN1 LMBR1L TRPM3 GREB1

6.37e-0519311775437_UP
DrugDeferoxamine mesylate [138-14-7]; Up 200; 6uM; MCF7; HT_HG-U133A

CDC42BPA CALCR ETV7 SLC24A3 GCKR NPFFR1 FAM120C

7.49e-0519811773842_UP
DrugSulfasalazine [599-79-1]; Up 200; 10uM; MCF7; HT_HG-U133A

MON2 ABCA1 SLC24A3 GCKR ZFY ITPKB UTY

7.49e-0519811775446_UP
Drugbromvalerylurea

CIB1 GSTCD

7.83e-0531172CID000002447
DrugN-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide

SCN3A SCN9A

7.83e-0531172ctd:C561228
DrugC14877

CYP2E1 GSTCD

7.83e-0531172CID011954075
Drugspiradoline

SCN3A SCN7A SCN9A SCNN1G

9.15e-05461174CID000005620
Drugbufuralol

CYP1B1 ABR CYP2E1 GSTCD

9.15e-05461174CID000071733
Drugisoflurane

CYP2E1 PIK3C2A SCN3A SCN7A SCN9A SCNN1G ALAD TNFAIP3

9.90e-052791178CID000003763
DrugScorpion Venoms

SCN2A SCN3A SCN9A

1.02e-04181173ctd:D012604
Drugdecamethrin

CYP2E1 DDC SCN1A SCN2A SCN3A SCN8A

1.09e-041461176ctd:C017180
Drugsalbutamol

DDC SCN3A SCN7A SCN9A SCNN1G TNFAIP3

1.09e-041461176CID000002083
Drugindoxacarb

SCN3A SCN7A SCN9A SCNN1G

1.17e-04491174CID000107720
Drug1,3-benzodioxole

CYP1B1 ABR CYP2E1

1.21e-04191173CID000009229
Drug2-xylene

CYP1B1 USP18 CYP2E1 TNFAIP3

1.37e-04511174ctd:C026114
Drugphenytoin

CYP2E1 LPIN1 SCN2A SCN3A SCN7A SCN9A SCNN1G

1.40e-042191177CID000001775
Drug3C etc

CYP1B1 CYP2E1 GSTCD

1.41e-04201173CID000164045
Drugkahweol

CYP2E1 PIK3C2A GSTCD TNFAIP3

1.48e-04521174CID000114778
DrugAPETx2 protein, Anthopleura elegantissima

SCN2A SCN8A

1.56e-0441172ctd:C501880
Drugremin

ABR CALCR

1.56e-0441172CID000006617
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

5.13e-13101116DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

5.13e-13101116DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

2.24e-12121116DOID:0060170 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SLC24A3 BDKRB1 SLC24A4 SCN1A SCN2A SCN3A SCN7A SCN8A SCN9A

1.20e-081631119DOID:1826 (implicated_via_orthology)
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN9A

1.32e-06221114DOID:2030 (implicated_via_orthology)
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A SCN9A

4.28e-0691113C3502809
DiseaseEarly Infantile Epileptic Encephalopathy 6

SCN1A SCN9A

1.40e-0521112C4551549
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A SCN9A

1.44e-05131113C0751122
DiseaseB Virus Infection

SCN8A SCN9A

4.20e-0531112C0037140
DiseaseBenign familial infantile epilepsy

SCN2A SCN8A

4.20e-0531112cv:C5575231
DiseasePostherpetic neuralgia

SCN8A SCN9A

4.20e-0531112C0032768
DiseaseHerpesviridae Infections

SCN8A SCN9A

4.20e-0531112C0019372
Diseaselactosyl-N-palmitoyl-sphingosine (d18:1/16:0) measurement

ABCA7 GSDMA

1.39e-0451112EFO_0800429
DiseaseFamilial benign neonatal epilepsy

SCN2A SCN8A

2.08e-0461112C0220669
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

2.91e-0471112C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

2.91e-0471112C0751057
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A SCN9A

3.87e-0481112C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A SCN9A

3.87e-0481112C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A SCN9A

3.87e-0481112C0338479
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A SCN9A

3.87e-0481112C0751120
DiseaseMyoclonic Encephalopathy

SCN1A SCN9A

3.87e-0481112C0438414
DiseaseMyoclonic Absence Epilepsy

SCN1A SCN9A

3.87e-0481112C0393703
DiseaseFebrile Convulsions

SCN1A SCN2A

4.96e-0491112C0009952
DiseaseMyoclonic Epilepsy

SCN1A SCN9A

4.96e-0491112C0014550
DiseaseThromboembolism

CAMKK1 OR51E2 OR52A4P

6.13e-04441113HP_0001907
Diseasemorbid obesity (is_marker_for)

CYP2E1 LPIN1

6.19e-04101112DOID:11981 (is_marker_for)
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A SCN9A

6.19e-04101112C0917800
Diseasepigmentation disease (is_implicated_in)

SLC24A4 HERC2

7.54e-04111112DOID:10123 (is_implicated_in)
DiseaseMyoclonic Astatic Epilepsy

SCN1A SCN9A

7.54e-04111112C0393702
DiseaseEpilepsy

SCN1A SCN2A SCN8A SCN9A

7.79e-041091114C0014544
Diseasehair colour measurement, hair morphology measurement

SLC24A4 HERC2

9.03e-04121112EFO_0007821, EFO_0007822
DiseaseSjogren's Syndrome

NCF1 TNFAIP3

1.06e-03131112C1527336
DiseaseSicca Syndrome

NCF1 TNFAIP3

1.06e-03131112C0086981
Diseasecutaneous melanoma

CYP1B1 GPR37 HERC2 CORO7

1.15e-031211114EFO_0000389
Diseasefactor VII measurement

GCKR FOCAD SCN2A

1.18e-03551113EFO_0004619
DiseaseMMR-related febrile seizures

SCN1A SCN2A

1.43e-03151112EFO_0006519
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

1.63e-03161112C0393706
DiseaseNight blindness, congenital stationary

LRIT3 GRK1

1.84e-03171112C0339535
Diseaseage at menarche

SLC24A3 ZFHX4 TRPM3 SCN2A KDM4A GREB1 CADPS2 UNC80

1.85e-035941118EFO_0004703
Diseasesmoking behavior

CDC42BPA CAMKK1 DOCK10 SLC24A3 KDM4A CADPS2

1.87e-033411116EFO_0004318
DiseaseAge-related macular degeneration

ABCA4 ERCC6

2.06e-03181112cv:C0242383
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

2.06e-03181112HP_0002373
Diseasesynophrys measurement

SLC24A4 ZFHX4 HERC2

2.17e-03681113EFO_0007906
Diseaseskin pigmentation

SLC24A4 HERC2 CADPS2

2.27e-03691113EFO_0003784
Diseasefamilial hyperlipidemia (biomarker_via_orthology)

ABCA1 CYP2E1

2.30e-03191112DOID:1168 (biomarker_via_orthology)
Diseaseinferior parietal cortex volume measurement

TBC1D15 GREB1

2.30e-03191112EFO_0010307
Diseaseunipolar depression, bipolar disorder, schizophrenia, sex interaction measurement

DNAJC7 GPR61 TRPM3

2.98e-03761113EFO_0003761, EFO_0008343, MONDO_0004985, MONDO_0005090
Diseasestomach carcinoma (is_marker_for)

KDM4A TNFAIP3

3.67e-03241112DOID:5517 (is_marker_for)
DiseaseEpilepsy, Cryptogenic

SCN1A SCN2A SCN8A

3.70e-03821113C0086237
DiseaseAwakening Epilepsy

SCN1A SCN2A SCN8A

3.70e-03821113C0751111
DiseaseAura

SCN1A SCN2A SCN8A

3.70e-03821113C0236018

Protein segments in the cluster

PeptideGeneStartEntry
RKLRHVFLFTDVLLC

ABR

316

Q12979
LHRVLPTFIISICFF

BDKRB1

36

P46663
SFHFTPVLVCKDPIR

ADPGK

461

Q9BRR6
NAVLRKLLIVFPHFC

ABCA4

1826

P78363
LVRRDPVSCKILHFF

CALCR

211

P30988
PLVAFLLFCLHVLFK

ADAM20

701

O43506
HTSILPKEICARTFF

COQ10B

51

Q9H8M1
SLIDFKRFHPFCLVL

GSDMA

26

Q96QA5
DILKSVFLIFPHFCL

ABCA1

1801

O95477
EIARFFKLHERKCEP

CORO1C

331

Q9ULV4
LRKHDVCFLITVRPT

AQR

556

O60306
VPVRDCLVATIHFLK

AADACL3

161

Q5VUY0
RLLDDVSFHPCIRFK

AP3M1

226

Q9Y2T2
VPCHLRDKFVLRFAI

DDC

436

P20711
RLAHLVLFCPFSKRL

DIPK1B

6

Q5VUD6
VHELDLFRCFRPVLT

DENND6B

246

Q8NEG7
DGAKTFIIFLCHLLR

BBS10

81

Q8TAM1
ASRIFFEKVLPCIVI

DISP1

701

Q96F81
SRILKQVFLIFPHFC

ABCA7

1681

Q8IZY2
FFVPSLEKICERLHL

SLC24A4

121

Q8NFF2
PCNVIADILFRKHFD

CYP2E1

176

P05181
RLLDDVSFHPCVRFK

AP3M2

226

P53677
KPVDFLEFRRRVVCH

ERCC6

976

P0DP91
RFRCIVHPFREKLTL

NPFFR1

141

Q9GZQ6
LAELVPRLFRAVCKF

PCDHA7

56

Q9UN72
THRAILFCKQRDLLP

OSGEPL1

301

Q9H4B0
PAEERKLRHLLCFEV

ESPNL

871

Q6ZVH7
EIDHFFCEAPVLVRL

OR2T12

171

Q8NG77
PALRKFVFVFHLCLV

GPR61

71

Q9BZJ8
SLPDHLLVCAVDKRF

GREB1

126

Q4ZG55
HLLRKTFPNLLVACD

ALAD

106

P13716
LLHSPFFKVLVALAC

HERC2

3841

O95714
CDLREKLDSFLPAHL

FRMD8

191

Q9BZ67
CPFIDDFILALHRKI

CAMKK1

351

Q8N5S9
CDLREKLDSFLPAHL

FRMD8P1

191

Q9BZ68
FEEELKSLLCHLPRI

DDX56

176

Q9NY93
KICSLRFHPLAANVL

CORO7

596

P57737
HFFTSKIVRLCVDDP

PLXNA1

276

Q9UIW2
VIHQFFCDIPSLLKL

OR14C36

171

Q8NHC7
ELHQFFCDVPALLKL

OR14K1

171

Q8NGZ2
EIDHFFCETPVLVRL

OR2T8

171

A6NH00
FPLPLLIKRLAFCHS

OR51E2

156

Q9H255
IFITVFHLPLKEARL

OR52A4P

226

A6NMU1
LVCTFFHPLLRDEKA

PIK3C2A

1526

O00443
TKISRCPHLLDFFKV

NCF1

106

P14598
VLTRELLFFPEHARK

FAM205A

576

Q6ZU69
VLTRELLFFPEHARK

FAM205BP

306

Q63HN1
PLESTECKHAFFLRL

KAT14

766

Q9H8E8
VVFITCFRHKIPNLE

KDM4A

876

O75164
RLCEVVDHVFPLLKR

LPIN1

841

Q14693
PCDILQLDFRHIRKT

LRCH1

666

Q9Y2L9
SLDKRVILIFHCEFS

CDC25B

476

P30305
ILFQRAELEHCLKPS

LRIT3

241

Q3SXY7
EALSKAIVLCFRLHF

MON2

141

Q7Z3U7
EIDHFFCETPVLVRL

OR2T33

171

Q8NG76
FFVPSLEKICERLHL

SLC24A3

131

Q9HC58
KARCIESLLRAIHFP

GCKR

531

Q14397
PHLRKCFENIARLLF

DNAH1

1351

Q9P2D7
RRFVLELPDCTLAHF

CMPK2

31

Q5EBM0
HRKFPENVECLRFLV

IFT88

681

Q13099
IFFCLPLVIFHELTK

GPR37

311

O15354
EFCRKHFLIGILLRE

DOCK10

1146

Q96BY6
ALCILTKDDFRHRAP

ETV7

86

Q9Y603
HCVRLALIRFRVKVF

FAM120C

221

Q9NX05
VRHNLCFRDSFEKVP

FOXR1

221

Q6PIV2
ANPCKLDHAFLFRIL

CADPS2

636

Q86UW7
LRCLIKFSSPHLLEA

CENPN

291

Q96H22
VRLIFERFVAKPCAI

CERS6

51

Q6ZMG9
LCRPLDSRLEHVDFK

DENND2C

656

Q68D51
HCIDLFLDFITVFRK

TMBIM6

206

P55061
PEEKHTFCLLLRAIN

DNAH14

2946

Q0VDD8
DRALEFAPACHRFKI

DNAJC7

166

Q99615
FLALDKCLPHRDFLQ

DBR1

251

Q9UK59
FILDKFLRHCESLRP

CYP1B1

271

Q16678
FRDETCDKLRAHPLF

GRK1

441

Q15835
LFRQFCDTKPTLKRH

GRK4

66

P32298
INHPIFSRKIFDFCI

DNA2

746

P51530
LTLKCLAIHDVIRFP

DHX40

436

Q8IX18
KVHFRKLDFPAVTIC

SCNN1G

86

P51170
LPCIHHFLVIISRKF

GSTCD

291

Q8NEC7
FIEEVCLSLLRHPVF

FOCAD

246

Q5VW36
LLHLELKRCLFTVEP

FUZ

301

Q9BT04
VREHLRKLCLREFPC

LRRC43

31

Q8N309
CTKILTRLFRVFVHV

MOB3C

151

Q70IA8
IDLLNRRIFIPCHDK

OTOGL

1741

Q3ZCN5
EIAHFFCDITPVLKL

OR1N1

171

Q8NGS0
LVCKLPRFFVHSLHR

RPUSD4

341

Q96CM3
VDPSFCRAKEIHLRL

UTY

156

O14607
FLLRIASHPILCRDK

SNX4

161

O95219
TFQLRHILKARCDPV

TRIM33

436

Q9UPN9
SACHFLVEKRLARPV

TDRD6

946

O60522
LCHIFLTRFKKPAEF

LMBR1L

36

Q6UX01
IRTTLEVSPFFKCHE

ITPKB

861

P27987
IHCLDILFAFTKRVL

SCN9A

1836

Q15858
RIHCLDILFAFTKRV

SCN3A

1846

Q9NY46
FFLRHAKQIFPVLDC

SUPV3L1

161

Q8IYB8
VIHASRKDIPCIFRV

CDC42BPA

1151

Q5VT25
RIHCLDILFAFTKRV

SCN1A

1861

P35498
FLTKQEILLAHRRFC

CIB1

21

Q99828
KCNVVFPRIFDLITH

ZFHX4

2271

Q86UP3
ELFVFLFAPLVHRIK

UNC80

186

Q8N2C7
CFDILFHDPAVTLVK

VNN1

211

O95497
FCPQFREIIHKALID

TNFAIP3

56

P21580
KPQDVVRILTCKHFF

RNF148

266

Q8N7C7
SPVLKRHLQVFLDCR

SPIDR

826

Q14159
LCHAAFLPSVRLLKA

TRPM3

46

Q9HCF6
RIHCLDILFAFTKRV

SCN2A

1851

Q99250
RIHCLDILFAFTKRV

SCN8A

1841

Q9UQD0
VFCLKDDVVLPALHF

TBC1D15

151

Q8TC07
RPKELRFHSILKVDC

PHLDA2

46

Q53GA4
VFKRICAPLHAEVFC

nan

111

Q6ZVL8
FEVCARRLKLAHFCP

nan

406

Q3C1V9
LKTLEDALHCFFQPR

USP41

206

Q3LFD5
FIHRERLVAEKLSPC

ZMYM6

1011

O95789
CTAEPRFAAQLRKLH

TTC12

676

Q9H892
RDKRFFIPECLKHIF

PLEKHG7

506

Q6ZR37
CIRRTTIKVLVHPFF

SCN7A

106

Q01118
LKTLEDALHCFFQPR

USP18

206

Q9UMW8
KTAFVERFQHLPCVL

TRIM4

356

Q9C037
LNVEKAPFLCERLHI

TXNDC9

126

O14530
EVLKDTIFPSRICHR

PRR11

96

Q96HE9
QNFPEILCIHLKRFR

USP33

606

Q8TEY7
CDFKIADPFVLSRHI

ZFY

691

P08048
ATLKFEPFVLHVQCR

TYW3

96

Q6IPR3