Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionthreonine-tRNA ligase activity

TARS3 TARS1

5.11e-053832GO:0004829
GeneOntologyCellularComponentMLL1 complex

RBBP5 KAT8 CHD8

2.75e-0432833GO:0071339
GeneOntologyCellularComponentMLL1/2 complex

RBBP5 KAT8 CHD8

3.02e-0433833GO:0044665
GeneOntologyCellularComponentaryl hydrocarbon receptor complex

ARNT HSP90AB1

4.29e-048832GO:0034751
GeneOntologyCellularComponentperineuronal net

PTPRZ1 BCAN

6.87e-0410832GO:0072534
GeneOntologyCellularComponentperisynaptic extracellular matrix

PTPRZ1 BCAN

8.37e-0411832GO:0098966
GeneOntologyCellularComponentmethyltransferase complex

RBBP5 KAT8 CHD8 SNRPD3

9.05e-04108834GO:0034708
DomainNfI_DNAbd_pre-N

NFIA NFIC NFIX

3.25e-074823PF10524
DomainCTF_NFI

NFIA NFIC NFIX

3.25e-074823PF00859
DomainCTF_NFI_1

NFIA NFIC NFIX

3.25e-074823PS00349
DomainCTF/NFI

NFIA NFIC NFIX

3.25e-074823IPR000647
DomainCTF_NFI_2

NFIA NFIC NFIX

3.25e-074823PS51080
DomainCTF/NFI_DNA-bd_N

NFIA NFIC NFIX

3.25e-074823IPR019548
DomainCTF/NFI_DNA-bd_CS

NFIA NFIC NFIX

3.25e-074823IPR019739
DomainCTF/NFI_DNA-bd-dom

NFIA NFIC NFIX

3.25e-074823IPR020604
DomainMAD_homology1_Dwarfin-type

NFIA NFIC NFIX

1.74e-0512823IPR003619
DomainDWA

NFIA NFIC NFIX

1.74e-0512823SM00523
DomainMH1

NFIA NFIC NFIX

1.74e-0512823PF03165
DomainssDNA-bd_transcriptional_reg

NFIC NFIX

5.70e-053822IPR009044
DomainThrRS_core

TARS3 TARS1

5.70e-053822IPR033728
DomainThr-tRNA-ligase_IIa

TARS3 TARS1

5.70e-053822IPR002320
Domainfn3

EPHB6 ANOS1 PTPRG TIE1 PTPRZ1 TEK

7.89e-05162826PF00041
DomainFN3

EPHB6 ANOS1 PTPRG TIE1 PTPRZ1 TEK

1.63e-04185826SM00060
DomainFN3

EPHB6 ANOS1 PTPRG TIE1 PTPRZ1 TEK

2.43e-04199826PS50853
DomainTGS

TARS3 TARS1

2.82e-046822IPR004095
DomainTGS

TARS3 TARS1

2.82e-046822PF02824
DomainFN3_dom

EPHB6 ANOS1 PTPRG TIE1 PTPRZ1 TEK

3.16e-04209826IPR003961
DomainTGS-like

TARS3 TARS1

3.94e-047822IPR012676
DomaintRNA_SAD

TARS3 TARS1

3.94e-047822SM00863
DomaintRNA_SAD

TARS3 TARS1

3.94e-047822IPR012947
DomaintRNA_SAD

TARS3 TARS1

3.94e-047822PF07973
DomainThr/Ala-tRNA-synth_IIc_edit

TARS3 TARS1

5.24e-048822IPR018163
DomainGrowth_fac_rcpt_

EPHB6 TMEM67 IGFBP5 TIE1 TEK

6.20e-04156825IPR009030
Domain-

EPHB6 ANOS1 PTPRG TIE1 PTPRZ1 CLMP BCAN TEK ADAMTSL3 PLXNB1

6.35e-0466382102.60.40.10
DomainHGTP_anticodon

TARS3 TARS1

6.72e-049822PF03129
Domainaa-tRNA-synt_IIb

TARS3 TARS1

1.02e-0311822IPR002314
DomaintRNA-synt_2b

TARS3 TARS1

1.02e-0311822PF00587
Domain-

TARS3 TARS1

1.02e-03118223.40.50.800
DomainIg-like_fold

EPHB6 ANOS1 PTPRG TIE1 PTPRZ1 CLMP BCAN TEK ADAMTSL3 PLXNB1

1.03e-037068210IPR013783
DomainWD40_repeat

RBBP5 KIF21A HERC2 TAF5 SEC31B TBL1XR1

1.25e-03272826IPR001680
DomainWD_REPEATS_1

RBBP5 KIF21A HERC2 TAF5 SEC31B TBL1XR1

1.40e-03278826PS00678
DomainWD_REPEATS_2

RBBP5 KIF21A HERC2 TAF5 SEC31B TBL1XR1

1.43e-03279826PS50082
DomainWD_REPEATS_REGION

RBBP5 KIF21A HERC2 TAF5 SEC31B TBL1XR1

1.43e-03279826PS50294
DomainBeta-grasp_dom

TARS3 TARS1

1.67e-0314822IPR012675
Domain-

TARS3 TARS1

1.67e-03148223.10.20.30
DomainAnticodon-bd

TARS3 TARS1

1.67e-0314822IPR004154
DomainHistone_H2A_CS

H2AZ2 H2AZ1

1.93e-0315822IPR032458
DomainHistone_H2A_C

H2AZ2 H2AZ1

2.48e-0317822IPR032454
DomainALPHA_CA_2

PTPRG PTPRZ1

2.48e-0317822PS51144
DomainCarb_anhydrase

PTPRG PTPRZ1

2.48e-0317822PF00194
DomainCarb_anhydrase

PTPRG PTPRZ1

2.48e-0317822SM01057
Domain-

PTPRG PTPRZ1

2.48e-03178223.10.200.10
DomainHistone_H2A_C

H2AZ2 H2AZ1

2.48e-0317822PF16211
DomainCarbonic_anhydrase_a

PTPRG PTPRZ1

2.48e-0317822IPR001148
Domainaa-tRNA-synth_II

TARS3 TARS1

2.78e-0318822IPR006195
DomainZZ

HERC2 NBR1

2.78e-0318822PF00569
DomainZF_ZZ_2

HERC2 NBR1

2.78e-0318822PS50135
DomainZF_ZZ_1

HERC2 NBR1

2.78e-0318822PS01357
DomainAA_TRNA_LIGASE_II

TARS3 TARS1

2.78e-0318822PS50862
DomainZnf_ZZ

HERC2 NBR1

3.10e-0319822IPR000433
DomainZnF_ZZ

HERC2 NBR1

3.10e-0319822SM00291
Domain-

RBBP5 KIF21A TAF5 SEC31B TBL1XR1 PLXNB1

3.45e-033338262.130.10.10
DomainWD40/YVTN_repeat-like_dom

RBBP5 KIF21A TAF5 SEC31B TBL1XR1 PLXNB1

3.55e-03335826IPR015943
DomainEGF_3

FAT2 TIE1 BCAN TEK SSPOP

3.76e-03235825PS50026
DomainHISTONE_H2A

H2AZ2 H2AZ1

3.79e-0321822PS00046
Domain-

EPHB6 HERC2 SSPOP

4.07e-03738232.60.120.260
DomainH2A

H2AZ2 H2AZ1

4.54e-0323822SM00414
DomainHistone_H2A

H2AZ2 H2AZ1

4.54e-0323822IPR002119
DomainMetal_Hydrolase

AMDHD1 ADA2

4.94e-0324822IPR032466
DomainEGF_1

FAT2 TIE1 BCAN TEK SSPOP

5.30e-03255825PS00022
DomainWD40

RBBP5 KIF21A TAF5 SEC31B TBL1XR1

5.65e-03259825PF00400
DomainWD40_repeat_CS

KIF21A TAF5 SEC31B TBL1XR1

5.89e-03164824IPR019775
DomainEGF_2

FAT2 TIE1 BCAN TEK SSPOP

6.22e-03265825PS01186
DomainWD40

RBBP5 KIF21A TAF5 SEC31B TBL1XR1

6.52e-03268825SM00320
PathwayREACTOME_RNA_POLYMERASE_III_TRANSCRIPTION

BDP1 NFIA NFIC NFIX

4.64e-0541694M739
Pubmed

Nuclear factor one transcription factors as epigenetic regulators in cancer.

NFIA NFIC NFIX

5.23e-08483328076901
Pubmed

Transcription factor NF 1 expression in involuting mammary gland.

NFIA NFIC NFIX

5.23e-08483310959417
Pubmed

Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH.

NFIA NFIC NFIX

5.23e-0848337590749
Pubmed

Altered expression of the developmentally regulated NFI gene family during phorbol ester-induced differentiation of human leukemic cells.

NFIA NFIC NFIX

5.23e-0848339052991
Pubmed

Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development.

NFIA NFIC NFIX

5.23e-0848339056636
Pubmed

Genomic organization, splice products and mouse chromosomal localization of genes for transcription factor Nuclear Factor One.

NFIA NFIC NFIX

5.23e-08483312568726
Pubmed

Regulation of the CYP3A4 and CYP3A7 promoters by members of the nuclear factor I transcription factor family.

NFIA NFIC NFIX

1.31e-07583319706729
Pubmed

Temporal control of a dendritogenesis-linked gene via REST-dependent regulation of nuclear factor I occupancy.

NFIA NFIC NFIX

2.61e-07683321270437
Pubmed

HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development.

TIE1 KAT8 TEK HSP90AB1

3.09e-072483421149574
Pubmed

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

UBE2J1 KCNA3 PTPRZ1 CYP4F12 GRIK5 TBL1XR1 DNMT1 HSP90AB1

3.35e-0727683828319085
Pubmed

NFI in the development of the olfactory neuroepithelium and the regulation of olfactory marker protein gene expression.

NFIA NFIC NFIX

4.56e-07783310762365
Pubmed

TGF-β/NF1/Smad4-mediated suppression of ANT2 contributes to oxidative stress in cellular senescence.

NFIA NFIC NFIX

4.56e-07783325220407
Pubmed

Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain.

H2AZ2 H2AZ1 CD68 PF4V1

9.03e-073183431712428
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

H2AZ2 NRDC KIF21A PSMC1 H2AZ1 ANKRD28 BRCC3 PRMT3 OSGEP TBL1XR1 SNRPD3 PRRC1 TARS1 MVK HSP90AB1

1.64e-061455831522863883
Pubmed

Nfix regulates fetal-specific transcription in developing skeletal muscle.

NFIA NFIC NFIX

2.13e-061183320178747
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

TICRR ARNT H2AZ2 NFIA RBBP5 NFIC NFIX KAT8 BRCC3 TAF5 ZBTB7B TBL1XR1 SNRPD3 DNMT1

2.18e-061294831430804502
Pubmed

Requirement of the MADS-box transcription factor MEF2C for vascular development.

ARNT TIE1 TEK

2.84e-06128339778514
Pubmed

The basic helix-loop-helix transcription factor, dHAND, is required for vascular development.

ARNT TIE1 TEK

3.68e-061383310675351
Pubmed

Nuclear factor I coordinates multiple phases of cerebellar granule cell development via regulation of cell adhesion molecules.

NFIA NFIC NFIX

3.68e-061383317553984
Pubmed

Large-scale structural analysis of the classical human protein tyrosine phosphatome.

PTPRG TIE1 PTPRZ1 TEK

4.97e-064783419167335
Pubmed

Tie-1: A potential target for anti-angiogenesis therapy.

TIE1 TEK

5.63e-06283226489611
Pubmed

Loss of threonyl-tRNA synthetase-like protein Tarsl2 has little impact on protein synthesis but affects mouse development.

TARS3 TARS1

5.63e-06283237059185
Pubmed

Histone H2A.Z is required for androgen receptor-mediated effects on fear memory.

H2AZ2 H2AZ1

5.63e-06283232916283
Pubmed

A threonyl-tRNA synthetase-like protein has tRNA aminoacylation and editing activities.

TARS3 TARS1

5.63e-06283229579307
Pubmed

Evidence for heterotypic interaction between the receptor tyrosine kinases TIE-1 and TIE-2.

TIE1 TEK

5.63e-06283210995770
Pubmed

Molecular cloning and characterization of mouse TIE and TEK receptor tyrosine kinase genes and their expression in hematopoietic stem cells.

TIE1 TEK

5.63e-0628328395828
Pubmed

Localization of the angiopoietin receptors Tie-1 and Tie-2 on the primary cilia in the female reproductive organs.

TIE1 TEK

5.63e-06283215893943
Pubmed

The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells.

TIE1 TEK

5.63e-0628328846781
Pubmed

A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains.

TIE1 TEK

5.63e-0628321312667
Pubmed

Activation of the orphan endothelial receptor Tie1 modifies Tie2-mediated intracellular signaling and cell survival.

TIE1 TEK

5.63e-06283217504972
Pubmed

H2A.Z is dispensable for both basal and activated transcription in post-mitotic mouse muscles.

H2AZ2 H2AZ1

5.63e-06283232266374
Pubmed

Requirement for the TIE family of receptor tyrosine kinases in adult but not fetal hematopoiesis.

TIE1 TEK

5.63e-06283214530387
Pubmed

Tie1-Tie2 interactions mediate functional differences between angiopoietin ligands.

TIE1 TEK

5.63e-06283220227369
Pubmed

Sex-specific effects of the histone variant H2A.Z on fear memory, stress-enhanced fear learning and hypersensitivity to pain.

H2AZ2 H2AZ1

5.63e-06283232868857
Pubmed

Tie2 receptor expression and phosphorylation in cultured cells and mouse tissues.

TIE1 TEK

5.63e-0628329108247
Pubmed

The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken.

H2AZ2 H2AZ1

5.63e-06283216204459
Pubmed

Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates.

H2AZ2 H2AZ1

5.63e-06283220003410
Pubmed

Role of the histone variant H2A.Z.1 in memory, transcription, and alternative splicing is mediated by lysine modification.

H2AZ2 H2AZ1

5.63e-06283238366138
Pubmed

H2A.Z facilitates licensing and activation of early replication origins.

H2AZ2 H2AZ1

5.63e-06283231875854
Pubmed

Exon structure of the nuclear factor I DNA-binding domain from C. elegans to mammals.

NFIA NFIC NFIX

7.18e-061683310087299
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

NFIA RBBP5 NFIC KMT5A KAT8 CHD8 HERC2 TBL1XR1 DNMT1

1.50e-0560883936089195
Pubmed

A Human IgSF Cell-Surface Interactome Reveals a Complex Network of Protein-Protein Interactions.

TIE1 TEK

1.69e-05383232822567
Pubmed

SET8 prevents excessive DNA methylation by methylation-mediated degradation of UHRF1 and DNMT1.

KMT5A DNMT1

1.69e-05383231400111
Pubmed

CREB binding protein coordinates the function of multiple transcription factors including nuclear factor I to regulate phosphoenolpyruvate carboxykinase (GTP) gene transcription.

NFIA NFIC

1.69e-05383210085123
Pubmed

The Orphan Receptor Tie1 Controls Angiogenesis and Vascular Remodeling by Differentially Regulating Tie2 in Tip and Stalk Cells.

TIE1 TEK

1.69e-05383226344773
Pubmed

Tie1 regulates the Tie2 agonistic role of angiopoietin-2 in human lymphatic endothelial cells.

TIE1 TEK

1.69e-05383222342979
Pubmed

The H2A.Z histone variant integrates Wnt signaling in intestinal epithelial homeostasis.

H2AZ2 H2AZ1

1.69e-05383231015444
Pubmed

Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain.

H2AZ2 H2AZ1

1.69e-05383238091994
Pubmed

Vascular endothelial growth factor modulates the Tie-2:Tie-1 receptor complex.

TIE1 TEK

1.69e-05383211866538
Pubmed

Novel RPTPγ and RPTPζ splice variants from mixed neuron-astrocyte hippocampal cultures as well as from the hippocampi of newborn and adult mice.

PTPRG PTPRZ1

1.69e-05383238952869
Pubmed

Brevican distinctively assembles extracellular components at the large diameter nodes of Ranvier in the CNS.

PTPRZ1 BCAN

1.69e-05383219141078
Pubmed

Tie2-dependent knockout of HIF-1 impairs burn wound vascularization and homing of bone marrow-derived angiogenic cells.

ARNT TEK

1.69e-05383222028336
Pubmed

Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification.

NFIA NFIX

1.69e-05383231128945
Pubmed

The p53 tumor suppressor gene is regulated in vivo by nuclear factor 1-C2 in the mouse mammary gland during pregnancy.

NFIA NFIC

1.69e-05383212955085
Pubmed

Angiopoietin-Tie signalling in the cardiovascular and lymphatic systems.

TIE1 TEK

1.69e-05383227941161
Pubmed

Ligand-independent Tie2 dimers mediate kinase activity stimulated by high dose angiopoietin-1.

TIE1 TEK

1.69e-05383223504320
Pubmed

Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival.

H2AZ2 H2AZ1

1.69e-05383234525369
Pubmed

Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2.

TIE1 TEK

1.69e-05383217728252
Pubmed

Chromatin remodeler Znhit1 preserves hematopoietic stem cell quiescence by determining the accessibility of distal enhancers.

H2AZ2 H2AZ1

1.69e-05383232694618
Pubmed

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation.

TIE1 TEK

1.69e-0538327596437
Pubmed

Interaction of the TEK and TIE receptor tyrosine kinases during cardiovascular development.

TIE1 TEK

1.69e-05383210498691
Pubmed

A unique pattern of Tie1 expression in the developing murine lung.

TIE1 TEK

1.69e-05383212554357
Pubmed

Protein tyrosine phosphatase zeta/RPTPbeta interacts with PSD-95/SAP90 family.

PTPRG PTPRZ1

1.69e-05383210521598
Pubmed

Tie1 controls angiopoietin function in vascular remodeling and inflammation.

TIE1 TEK

1.69e-05383227548530
Pubmed

Nuclear factor I transcription factors regulate IGF binding protein 5 gene transcription in human osteoblasts.

IGFBP5 NFIC

1.69e-05383218809517
Pubmed

The molecular balance between receptor tyrosine kinases Tie1 and Tie2 is dynamically controlled by VEGF and TNFα and regulates angiopoietin signalling.

TIE1 TEK

1.69e-05383222235284
Pubmed

Role of the aryl hydrocarbon receptor nuclear translocator protein in aryl hydrocarbon (dioxin) receptor action.

ARNT HSP90AB1

1.69e-0538328396713
Pubmed

Nuclear Factor I/A Controls A-fiber Nociceptor Development.

H2AZ2 NFIA

1.69e-05383232221845
Pubmed

NFI-B3, a novel transcriptional repressor of the nuclear factor I family, is generated by alternative RNA processing.

NFIC NFIX

1.69e-0538329099724
Pubmed

Identification and characterization of the two isoforms of the vertebrate H2A.Z histone variant.

H2AZ2 H2AZ1

1.69e-05383220299344
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KCNA3 KIF21A ANKRD28 CHD8 GRIK5 HERC2 CTNND1 TAF5 TBL1XR1 DNMT1 HSP90AB1

1.82e-05963831128671696
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

NFIA PSMC1 BRCC3 HERC2 CTNND1 CBLB NBR1 DNMT1

2.01e-0548183828190767
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

KIDINS220 GUCY1B2 NRDC RBBP5 PSMC1 H2AZ1 PRMT3 CTNND1 SNRPD3 NBR1 TARS1 DNMT1 HSP90AB1

3.18e-051425831330948266
Pubmed

Differential neuronal and glial expression of nuclear factor I proteins in the cerebral cortex of adult mice.

NFIA NFIX

3.37e-05483228295292
Pubmed

Gene regulatory networks controlling vertebrate retinal regeneration.

NFIA NFIX

3.37e-05483233004674
Pubmed

Expression of VEGF receptors VEFGR-1 and VEGFR-2, angiopoietin receptors Tie-1 and Tie-2 in chorionic villi tree during early pregnancy.

TIE1 TEK

3.37e-05483220164029
Pubmed

NFIA and GATA3 are crucial regulators of embryonic articular cartilage differentiation.

NFIA NFIX

3.37e-05483229247144
Pubmed

The distribution of angiopoietin-1, angiopoietin-2 and their receptors tie-1 and tie-2 in the very early human placenta.

TIE1 TEK

3.37e-05483218675456
Pubmed

Signaling and functions of angiopoietin-1 in vascular protection.

TIE1 TEK

3.37e-05483216645151
Pubmed

RFX1 and NF-1 associate with P sequences of the human growth hormone locus in pituitary chromatin.

NFIC NFIX

3.37e-05483212624117
Pubmed

The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules.

PTPRG PTPRZ1

3.37e-05483220133774
Pubmed

A combinatorial role of angiopoietin-1 and orphan receptor TIE1 pathways in establishing vascular polarity during angiogenesis.

TIE1 TEK

3.37e-05483211172728
Pubmed

Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8.

RBBP5 CHD8

3.37e-05483220085832
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

ARNT NFIA RBBP5 NFIC NFIX ANKRD28 CTNND1 TBL1XR1 NBR1 HSP90AB1

3.76e-05857831025609649
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PTPRG PTPRZ1 PSMC1 PHLPP1 ANKRD28 BRCC3 HERC2 CTNND1 NBR1 DNMT1 HSP90AB1

3.96e-051049831127880917
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

KIDINS220 H2AZ2 H2AZ1 ANKRD28 PRMT3 OSGEP HERC2 DNMT1

4.16e-0553383825544563
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NFIA RBBP5 NFIC NFIX CHD8 TBL1XR1

4.55e-0526883633640491
Pubmed

The transcription factor gene Nfib is essential for both lung maturation and brain development.

NFIA NFIC NFIX

5.08e-053083315632069
Pubmed

TIE1 and TIE2 receptor tyrosine kinases inversely regulate embryonic angiogenesis by the mechanism of intussusceptive microvascular growth.

TIE1 TEK

5.60e-0558329683559
Pubmed

Expression of angiopoietin-1, 2 and 4 and Tie-1 and 2 in gastrointestinal stromal tumor, leiomyoma and schwannoma.

TIE1 TEK

5.60e-05583217724803
Pubmed

Identification of genes differentially expressed in human primary lung squamous cell carcinoma.

IGFBP5 TBL1XR1

5.60e-05583217316888
Pubmed

Vascularization of the mouse embryo: a study of flk-1, tek, tie, and vascular endothelial growth factor expression during development.

TIE1 TEK

5.60e-0558327647376
Pubmed

A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

ARNT HSP90AB1

5.60e-0558329083006
Pubmed

HDAC1 bound to the Cyp1a1 promoter blocks histone acetylation associated with Ah receptor-mediated trans-activation.

ARNT DNMT1

5.60e-05583217707923
Pubmed

Control of neurogenic competence in mammalian hypothalamic tanycytes.

NFIA NFIX

5.60e-05583234049878
Pubmed

RPTPζ/phosphacan is abnormally glycosylated in a model of muscle-eye-brain disease lacking functional POMGnT1.

PTPRZ1 BCAN

5.60e-05583222728091
Pubmed

Analysis of histone variant constraint and tissue expression suggests five potential novel human disease genes: H2AFY2, H2AFZ, H2AFY, H2AFV, H1F0.

H2AZ2 H2AZ1

5.60e-05583235072799
Pubmed

Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain.

PTPRG PTPRZ1

5.60e-0558322169617
Pubmed

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

RBBP5 KAT8 CHD8

5.61e-053183315960975
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

NRDC RBBP5 PSMC1 PON2 ANKRD28 PRMT3 TBL1XR1 HSP90AB1

5.88e-0556083835241646
InteractionHDAC1 interactions

ARNT KCNA3 RBBP5 NFIX PSMC1 H2AZ1 PHLPP1 ANKRD28 CHD8 BRCC3 PRMT3 ZBTB7B TBL1XR1 DNMT1 HR HSP90AB1

7.14e-0611088116int:HDAC1
GeneFamilyFibronectin type III domain containing

EPHB6 ANOS1 PTPRG TIE1 PTPRZ1 TEK

1.48e-05160606555
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

HERC2 NBR1

1.60e-031860291
GeneFamilyWD repeat domain containing

RBBP5 KIF21A TAF5 SEC31B TBL1XR1

1.75e-03262605362
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRG PTPRZ1

2.18e-0321602813
GeneFamilyImmunoglobulin like domain containing

TIE1 CLMP TEK ADAMTSL3

3.85e-03193604594
ToppCellBronchial_Biopsy|World / Tissue, Lineage and Cell class of Lung Cells from 10X

EPHB6 ANOS1 FAT2 IGFBP5 NFIA PTPRZ1 RPS4Y1 KIF21A

3.63e-09198838f5b7013045b61fc56894f80092f799770dde1c8f
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

IGFBP5 PTPRG NFIA CLMP ADAMTSL3 DNMT1 HR

8.11e-08195837ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell10x_3'_v2v3-Neoplastic|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IGFBP5 NFIA PTPRZ1 NFIX KIF21A PON2 BCAN

9.63e-08200837e9c7d7cb5fa63fc92aa91d02ae8bd05438d465bc
ToppCellBasal_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ANOS1 FAT2 IGFBP5 PTPRZ1 HSD17B13 PLXNB1

4.10e-0715283672499e4d2b374ef5f1621c89d94727ecf4bd4d5d
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGFBP5 APCDD1 NFIA PDE5A CLMP ADAMTSL3

1.60e-0619283620ede290e01ad574afd122d72b59dbc52c595fad
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMEM67 IGFBP5 NFIA PTPRZ1 NFIX HSD17B13

1.65e-06193836ea345d34440b25f65358a53dc72831998d1c3620
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

PTPRG APCDD1 NFIA CLMP ADAMTSL3 CBLB

1.76e-06195836ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 IGFBP5 PTPRG TIE1 PHLPP1 TEK

1.86e-06197836cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM67 IGFBP5 NFIA NFIC PDE5A CLMP

1.86e-061978369af431323da6d099459b7360af40e5df998cffbd
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial|6_mon / Sample Type, Dataset, Time_group, and Cell type.

ANOS1 IGFBP5 APCDD1 PTPRZ1 PON2 BCAN

1.86e-06197836965d5a3f8c9b12cb8a8d3429702ae29ebd8c6122
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial-Astroglia|6_mon / Sample Type, Dataset, Time_group, and Cell type.

ANOS1 IGFBP5 APCDD1 PTPRZ1 PON2 BCAN

1.86e-061978363f088eb29197bc575400d6dafd8083e69e4a149f
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NFIA PTPRZ1 NFIX KIF21A PON2 BCAN

1.97e-061998366723287924750a2247a07ab6e561066a97b09771
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

H2AZ2 PTPRZ1 PON2 H2AZ1 BCAN DNMT1

1.97e-061998360da69ca107e826740f0ba3159012aa25e1b9da6a
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FAT2 PTPRZ1 NFIX KIF21A CTNND1 PLXNB1

2.03e-0620083697f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IGFBP5 PTPRZ1 NFIX KIF21A PON2 BCAN

2.03e-062008364c20102de2ff7a38e5bff5c65e9fbd0d0310a302
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Macroglial-Astrocyte|10w / Sample Type, Dataset, Time_group, and Cell type.

IGFBP5 APCDD1 NFIA PTPRZ1 PON2 BCAN

2.03e-0620083675f5ea38fbd341b80a8058077a04447f0e0eea28
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

H2AZ2 NFIA PTPRZ1 PON2 H2AZ1 BCAN

2.03e-0620083638e681997913fcbc93f4e1715820e53844376eab
ToppCellcontrol-Lymphoid-NKT-proliferating|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NFIA PTPRZ1 RPS4Y1 NFIX H2AZ1 CTNND1

2.03e-06200836f8b5e5464b2ffef7b0ce75f60839c8ef791e17ba
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FAT2 PTPRZ1 NFIX KIF21A CTNND1 PLXNB1

2.03e-06200836ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT2 GLIPR1L2 CD68 CCL24 ADA2

4.19e-06128835cfc73cb803ba50a4a8709e19e70e1e399118c849
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

PTPRG APCDD1 NFIA CLMP CBLB

1.61e-051698356373562ab3b1765060212a6a53d6543e7e942e80
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA3 PDE5A ADAMTSL3 SSPOP PLXNB1

2.02e-0517783565709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA3 PDE5A ADAMTSL3 SSPOP PLXNB1

2.02e-051778358684d47a547e2a06496f15e8da0200ecddc431e0
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPHB6 IGFBP5 APCDD1 ADAMTSL3 HR

2.07e-05178835c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCellCOVID-19-kidney-Stressed_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK4 IGFBP5 PHLPP1 TEK HSP90AB1

2.13e-05179835754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM67 IGFBP5 PTPRG GLIPR1L2 CLMP

2.13e-05179835a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 PTPRZ1 PON2 BCAN TEK

2.31e-051828358a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 PTPRZ1 PON2 BCAN TEK

2.31e-05182835a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 PTPRZ1 PON2 BCAN TEK

2.31e-05182835831b5ce46b41efe01c4db6016c2f43148611373d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 PTPRZ1 PON2 BCAN TEK

2.31e-051828353cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 PTPRZ1 PON2 BCAN TEK

2.31e-051828355d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 PTPRZ1 PON2 BCAN TEK

2.31e-05182835e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 PTPRZ1 PON2 BCAN TEK

2.49e-05185835efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

APCDD1 NFIA CLMP ADAMTSL3 CBLB

2.49e-051858358f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 PTPRZ1 PON2 BCAN TEK

2.49e-051858352e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 PTPRZ1 PON2 BCAN TEK

2.49e-051858357aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 PTPRZ1 PON2 BCAN TEK

2.49e-05185835fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 PTPRZ1 PON2 BCAN TEK

2.62e-05187835daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 PTPRZ1 PON2 BCAN TEK

2.62e-051878355b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 NFIA PON2 PHLPP1 PLXNB1

2.69e-05188835505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 NFIA PON2 PHLPP1 PLXNB1

2.76e-05189835784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCellNon-neuronal-Non-dividing-Radial_Glia-oRG/Astrocyte-7|World / Primary Cells by Cluster

ANOS1 IGFBP5 PTPRZ1 PON2 BCAN

2.83e-051908358f1c490dd8e5f80382f5294fd1aa8cba4c3c647f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

APCDD1 PTPRZ1 PON2 PHLPP1 PLXNB1

2.83e-051908352de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

DOCK4 SLFN12L RPS4Y1 NFIX CBLB

2.83e-0519083562a3ec1ae0829602b0569cc051210551644f1d46
ToppCellNon-neuronal-Non-dividing-Radial_Glia-oRG/Astrocyte|World / Primary Cells by Cluster

ANOS1 IGFBP5 PTPRZ1 PON2 BCAN

2.83e-051908357dbfd543398c63cbe1e68b54bcb5e2291f521935
ToppCellCOVID-19-kidney-Stressed_EC|kidney / Disease (COVID-19 only), tissue and cell type

DOCK4 IGFBP5 TIE1 TEK HSP90AB1

2.90e-05191835d35aa842b813ea0eff7362abc894cca4e86b2fb2
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

PTPRG APCDD1 NFIA ADAMTSL3 CBLB

2.90e-05191835d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellfacs-Trachea-nan-18m-Mesenchymal-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFBP5 NFIA NFIC NFIX ADAMTSL3

2.98e-05192835f388a336062880609724e91bf51bd0f9c4da2f69
ToppCellfacs-Trachea-nan-18m-Mesenchymal|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFBP5 NFIA NFIC NFIX ADAMTSL3

2.98e-05192835ceadfbce037bef15523916ba091bb6c0d752cce5
ToppCell(7)_Epithelial_cells-(7)_Epithelial-H_(AT1)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

FAT2 PTPRZ1 RPS4Y1 ADA2 HR

2.98e-051928357a6dd2ae217b8f8e460d47ad128904408299458c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 PTPRG TIE1 ANKRD28 TEK

2.98e-051928353259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCellNon-neuronal-Non-dividing-Radial_Glia-oRG-34|World / Primary Cells by Cluster

ANOS1 NFIA PTPRZ1 PON2 BCAN

3.05e-05193835d55f792eb3db10452347681131e07e041348fd89
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK4 PTPRG PDE5A CLMP ADAMTSL3

3.05e-05193835b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TIE1 APCDD1 PTPRZ1 ANKRD28 TEK

3.05e-05193835cc355b2ed6510619cad969ae074126d7c8db784d
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

DOCK4 IGFBP5 TIE1 TEK CBLB

3.05e-05193835479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK4 SLFN12L PTPRG NFIA CBLB

3.13e-05194835b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellBL-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FAT2 PTPRG PTPRZ1 NFIX CTNND1

3.13e-051948352932f704656ca368565ec12f3452af3b18e8df12
ToppCellfacs-GAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIA NFIC NFIX CLMP ADAMTSL3

3.13e-051948359709dc95fb6982b6a0467b507845d5bc17252e3e
ToppCellfacs-GAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIA NFIC NFIX CLMP ADAMTSL3

3.13e-0519483593b7a9065430740ec31fce4e8c14ffccb498591d
ToppCellfacs-GAT-Fat-18m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIA NFIC NFIX CLMP ADAMTSL3

3.13e-051948350d2e65b44e3f143971c2fd24c4552f042b049cfa
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 IGFBP5 PTPRG TIE1 TEK

3.13e-05194835e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 IGFBP5 PTPRG TIE1 TEK

3.21e-0519583523ced69fd904f1d4114b1a7f99f4b5f65ea8824b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 PTPRG TIE1 ANKRD28 TEK

3.21e-05195835d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCellfacs-Trachea-18m-Mesenchymal|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IGFBP5 NFIA NFIX CLMP ADAMTSL3

3.21e-051958350d1876f6fdc1eafeb60d6fd7da5bce737d2b4a5a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 IGFBP5 PTPRG TIE1 TEK

3.29e-05196835023312af38f816a44b407e0daa32590d953caf99
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 IGFBP5 PTPRG TIE1 TEK

3.29e-051968357cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

EPHB6 NFIC RPS4Y1 NFIX CLMP

3.29e-0519683538da0751941adca650fe9b383d9f343153978eb5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 IGFBP5 PTPRG TIE1 TEK

3.29e-051968354cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn|World / Primary Cells by Cluster

EPHB6 NFIC RPS4Y1 NFIX CLMP

3.29e-05196835721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 IGFBP5 PTPRG TIE1 TEK

3.29e-05196835d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

H2AZ2 PTPRZ1 H2AZ1 BCAN HR

3.29e-051968358faac7fbdee3a9297023c3151ef1751605413e44
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.

IGFBP5 NFIC RPS4Y1 PON2 BCAN

3.37e-0519783558b957efd006f43c2fe55071d5c6d06c2e367e72
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 PTPRG TIE1 PHLPP1 TEK

3.37e-05197835412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Macroglial-Astroglia|6_mon / Sample Type, Dataset, Time_group, and Cell type.

ANOS1 IGFBP5 PTPRZ1 PON2 BCAN

3.45e-05198835715ecad21f572b195ff3b78216b1a7b32bbb4ace
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 IGFBP5 PTPRG TIE1 TEK

3.45e-0519883507701c73137947ed4a27e225975329235bbb8734
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTPRG TIE1 APCDD1 PON2 HERC2

3.45e-051988350a4626b51ba8b52acbaf616f0ced850079cd7149
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 IGFBP5 PTPRG TIE1 TEK

3.45e-0519883531ba87552be97c9b78c9e82f98e96699ccb19824
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Macroglial|6_mon / Sample Type, Dataset, Time_group, and Cell type.

ANOS1 IGFBP5 PTPRZ1 PON2 BCAN

3.45e-051988359d03768f8b6c74e060c5f045508538f9b331f469
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM67 IGFBP5 NFIA PDE5A CLMP

3.45e-05198835a883e25cb7a78b2ecfb15cef4633bdd02dfafb12
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TARS3 RPS4Y1 KIF21A ANKRD28 CBLB

3.45e-05198835162881a04a981741a0e26e32e0c3c694282701c6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 IGFBP5 PTPRG TIE1 TEK

3.45e-05198835fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UBE2J1 H2AZ2 H2AZ1 SNRPD3 DNMT1

3.45e-051988358bd9be3f57e7a27935c63c913e486872d52600e7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 IGFBP5 PTPRG TIE1 TEK

3.45e-051988350a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

H2AZ2 PTPRZ1 KIF21A H2AZ1 BCAN

3.45e-05198835a11ac83dbd69d1c068971266d7c7343d114a6294
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGFBP5 NFIA NFIC H2AZ1 PDE5A

3.53e-0519983501ab0363558f215f9979e20fd5170d8fee149cea
ToppCellPSB-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPHB6 ANOS1 FAT2 PTPRG PTPRZ1

3.53e-051998352add64c3e4cb6384ec381f34c3f1f77e13e3f27c
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NFIA PTPRZ1 NFIX PON2 BCAN

3.53e-0519983504e5cfb85c681fd3f4c1151062e4a0f460b55d5f
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGFBP5 NFIA NFIC NFIX PDE5A

3.53e-0519983549690494270981eec5b5261c59e0545dff90cc21
ToppCellNon-neuronal|World / Primary Cells by Cluster

H2AZ2 PTPRZ1 PON2 H2AZ1 BCAN

3.53e-05199835165d9de6cedc79e13bb6fa244e8898a5dacc54ff
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-OPC_related-Oligodendrocyte/OPC|2m / Sample Type, Dataset, Time_group, and Cell type.

APCDD1 NFIA PTPRZ1 NFIX PON2

3.62e-052008353c9a2f02294a9fb892b89e856291bd6423ffa0a9
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-OPC_related|2m / Sample Type, Dataset, Time_group, and Cell type.

APCDD1 NFIA PTPRZ1 NFIX PON2

3.62e-052008358e49e7e9b02d8411e4ffae1f5113a2c18f5bf179
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGFBP5 APCDD1 NFIA CLMP ADAMTSL3

3.62e-052008356f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCellNon-neuronal-Dividing-IPC-IPC-div2|World / Primary Cells by Cluster

H2AZ2 NFIC RPS4Y1 H2AZ1 DNMT1

3.62e-052008354923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGFBP5 APCDD1 NFIA CLMP ADAMTSL3

3.62e-052008353a164e3971bcd62b148b813171c103adb81f972e
ToppCellNon-neuronal-Dividing-IPC-IPC-div2-5|World / Primary Cells by Cluster

H2AZ2 NFIC RPS4Y1 H2AZ1 DNMT1

3.62e-05200835dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Macroglial|10w / Sample Type, Dataset, Time_group, and Cell type.

IGFBP5 NFIA PTPRZ1 PON2 BCAN

3.62e-05200835bda719369aa199902789061e223b129f70a1317a
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendendrocytes_NG2_cells_(Tnr-Cspg5)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TICRR GUCY1B2 CCL24 ADAMTSL3

5.17e-0510983487f647cfebbb7de725e434cc27058e1c6accbb90
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TICRR GUCY1B2 CCL24 ADAMTSL3

5.17e-05109834e3696d84da1dcd15f15d0434ea9d1955f2af22d6
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendendrocytes_NG2_cells_(Tnr-Cspg5)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TICRR GUCY1B2 CCL24 ADAMTSL3

5.17e-051098346678036ff66c825a18d2506e33be421c27cf82e1
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P3|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TICRR GUCY1B2 CCL24 ADAMTSL3

5.17e-05109834c9d1e69f9841135f4d114563a293a69a8ba5f965
Diseaseamino acid metabolic disorder (implicated_via_orthology)

TARS3 TARS1

3.92e-054762DOID:9252 (implicated_via_orthology)
Diseaseproteinuria (implicated_via_orthology)

TMEM67 OSGEP HR

6.34e-0530763DOID:576 (implicated_via_orthology)
DiseaseBardet-Biedl Syndrome

TMEM67 BBS10

5.01e-0413762C0752166
DiseaseBardet-Biedl syndrome (is_implicated_in)

TMEM67 BBS10

5.84e-0414762DOID:1935 (is_implicated_in)
DiseaseBardet-Biedl syndrome

TMEM67 BBS10

9.75e-0418762cv:C0752166
Diseasenevus count, cutaneous melanoma

ARNT NFIC HERC2

1.70e-0391763EFO_0000389, EFO_0004632
Diseasecolorectal health

CLMP GRIK5 HERC2 CBLB

1.83e-03201764EFO_0008460
DiseaseObesity

APCDD1 CD68 ZBTB7B BBS10

1.96e-03205764C0028754
Diseasenon-alcoholic fatty liver disease severity measurement

PTPRG ADA2

2.37e-0328762EFO_0008421

Protein segments in the cluster

PeptideGeneStartEntry
PIIHGLKGVVHHEKE

PTPRG

216

P23470
VKDGEPHFVVVHCTG

ARNT

296

P27540
GDVGVCIIPHVHSKD

BDP1

2006

A6H8Y1
LLFLGVCAHHIIPTG

CCL24

11

O00175
GHRHVVLGSLPGKIV

CHD8

301

Q9HCK8
HGHLCPIDTGLIEKN

DNMT1

416

P26358
IKATIAGGGVIPHIH

H2AZ2

101

Q71UI9
TPIHLSAACGHIGVL

ANKRD28

721

O15084
HIVTVASVCGHEGIP

HSD17B13

166

Q7Z5P4
SIVLCGPVHGLIEQH

BBS10

396

Q8TAM1
LCVQPHHIGVSVKEL

NFIA

161

Q12857
TKVQGSCEGAHPHLL

CD68

201

P34810
QGVLGGALTIPCHVH

BCAN

46

Q96GW7
HKPVGCLGEAGHVLS

ANOS1

531

P23352
HGEPIGRGTKVILHL

HSP90AB1

171

P08238
EGHVHIVEELLKCGV

KIDINS220

81

Q9ULH0
LCVQPHHIGVTIKEL

NFIX

161

Q14938
CQTKLHDIDGVPHLI

KMT5A

346

Q9NQR1
CAVTPCSKIGHIIHA

GLIPR1L2

171

Q4G1C9
GKKIVHVAVGALHCL

HERC2

3256

O95714
GQHVICVTPKLVEEH

KAT8

411

Q9H7Z6
LTGLCEPTPHDHIKV

CBLB

341

Q13191
PHRGHLGTKNLCVEV

HR

996

O43593
RHITSLEVIKAGPHC

PF4V1

56

P10720
GDGPCVVKTLTRHHL

PLXNB1

1421

O43157
ICHNTVHLDPKVGPT

FAT2

3736

Q9NYQ8
IGVSTVHRFGKHVPC

OR51I2

256

Q9H344
RVHTIPVCKEGIRGH

PDE5A

61

O76074
HPVTIGGKIVGSLCA

KCNA3

451

P22001
EEKPLHALLHGRGVC

IGFBP5

86

P24593
AKRHAVGPVVVHCSA

PTPRZ1

1921

P23471
NKPLVGVNHCIGHIE

OSGEP

101

Q9NPF4
RGIAKIISAHIHPVC

RBBP5

56

Q15291
SVDLPHCHLIKGIEA

PON2

36

Q15165
RTLPDGTHELIVHKC

DOCK4

516

Q8N1I0
TLISEPCGIKHIDCH

PRMT3

411

O60678
KGITCLIDIIGVHHN

CYP4F12

416

Q9HCS2
HVTIVAHLIKSCPGE

C1orf112

476

Q9NSG2
PKGAALHLHDIGIVT

ADA2

106

Q9NZK5
HTNGCVALGIKLPHT

APCDD1

406

Q8J025
GKCILPGLVDAHTHP

AMDHD1

76

Q96NU7
IKATIAGGGVIPHIH

H2AZ1

101

P0C0S5
VSHICGEKEIPHIKV

GRIK5

106

Q16478
LLDHPKKEVHLGACG

CTNND1

416

O60716
KGGIPCRLVHGSVKH

PACRGL

86

Q8N7B6
LTAEGKCHCPIGHIL

TMEM67

121

Q5HYA8
LIDLCKGPHVRHTGK

TARS3

336

A2RTX5
CRGPHVRHTGKIKAL

TARS1

261

P26639
CVRIFTGHKGPIHSL

TAF5

661

Q15542
CLGGHTEPVVLPVIH

SSPOP

5121

A2VEC9
VPCLKAGHVGVVSVE

NBR1

431

Q14596
HLVCKVARLGHSPQG

EPHB6

806

O15197
GLCHIVPGIIEAVAK

GUCY1B2

61

O75343
VGVKGIPHLVTHDAR

RPS4Y1

131

P22090
IGCLVVEDPVHGIHL

PRRC1

346

Q96M27
LCEGTLSPHVVAGLH

SEC31B

1116

Q9NQW1
PGCSVLLNHKVHAVI

PSMC1

146

P62191
VLCVQPHHIGVAVKE

NFIC

161

P08651
RGICIHTLTKHQEPV

TBL1XR1

431

Q9BZK7
IHIVPHVTIGKVCLE

BRCC3

216

P46736
TLLHCAAQKGHVPVL

ANKDD1A

126

Q495B1
VAEEKVTLPCHHQLG

CLMP

26

Q9H6B4
PKELIHGTIHCKAGV

SPATA4

126

Q8NEY3
HGTIHCKAGVPEILI

SPATA4

131

Q8NEY3
VCELLHHGGGTVLPS

TICRR

231

Q7Z2Z1
IIHTGEKPHACLLCG

ZNF705A

276

Q6ZN79
QECPVCHKIIHGAGK

ZBTB7B

346

O15156
IGKLPVHHFCVEKGT

SLFN12L

286

Q6IEE8
IQELIHGAHIGKPIS

SMC1B

61

Q8NDV3
PLQCIHIAEGHTKAV

KIF21A

1336

Q7Z4S6
LLVSAPGKVILHGEH

MVK

6

Q03426
GELEVLCKLGHHPNI

TIE1

886

P35590
KLGHRHGIDITCPQE

SPATA31D1

1416

Q6ZQQ2
VGKKICLSISGHHPE

UBE2J1

86

Q9Y385
VVELPSGHHLCKVKA

NRDC

896

O43847
PIKVLHEAEGHIVTC

SNRPD3

6

P62318
GELEVLCKLGHHPNI

TEK

871

Q02763
IIHTGEKPHACLLCG

ZNF705EP

276

A8MWA4
IIHTGEKPHACLLCG

ZNF705G

276

A8MUZ8
IIHIGEKPHACLLCG

ZNF705D

276

P0CH99
SKEVHGRERIHGCPV

ZNF236

1676

Q9UL36
LGGAAVLCHIKHDPV

PHLPP1

1261

O60346
VLCHIKHDPVDPGGS

PHLPP1

1266

O60346
IIHSGEKPHLCDICG

ZBTB49

471

Q6ZSB9
CTLIIHQRVHTGEKP

ZNF17

371

P17021
EHVGGCNPQLKLHIK

ADAMTSL3

511

P82987