Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsterol O-acyltransferase activity

SOAT2 SOAT1

5.88e-053892GO:0004772
GeneOntologyMolecularFunctioncholesterol O-acyltransferase activity

SOAT2 SOAT1

5.88e-053892GO:0034736
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR2B11 HCAR2 IL31RA DRD4 TIE1 OR13C5 OR6C2 LRP6 CASR CCR6 GRM8 OR10J1 OR10X1 CHRND FFAR4 EPHA1

2.87e-0413538916GO:0004888
DomainSterol_acyltranf_meta

SOAT2 SOAT1

2.25e-052892IPR030687
Domain-

RASA4 RASA4B

6.72e-0538924.10.1130.10
DomainOat_ACAT_DAG_ARE

SOAT2 SOAT1

6.72e-053892IPR014371
DomainFAM26

CALHM1 CALHM4

3.33e-046892IPR029569
DomainCa_hom_mod

CALHM1 CALHM4

3.33e-046892PF14798
DomainBTK

RASA4 RASA4B

7.91e-049892SM00107
DomainZnf_Btk_motif

RASA4 RASA4B

7.91e-049892IPR001562
DomainBTK

RASA4 RASA4B

7.91e-049892PF00779
DomainZF_BTK

RASA4 RASA4B

7.91e-049892PS51113
DomainVDCCAlpha1

CACNA1E CACNA1H

9.86e-0410892IPR002077
DomainMBOAT_fam

SOAT2 SOAT1

1.20e-0311892IPR004299
DomainMBOAT

SOAT2 SOAT1

1.20e-0311892PF03062
DomainNCD3G

CASR GRM8

1.69e-0313892PF07562
DomainGPCR_3_9-Cys_dom

CASR GRM8

1.69e-0313892IPR011500
DomainAAA

ATAD2B FIGN RFC5

1.95e-0352893PF00004
DomainRasGAP

RASA4 RASA4B

1.97e-0314892SM00323
DomainGPCR_3_CS

CASR GRM8

1.97e-0314892IPR017979
DomainRasGAP_CS

RASA4 RASA4B

1.97e-0314892IPR023152
DomainATPase_AAA_core

ATAD2B FIGN RFC5

2.18e-0354893IPR003959
DomainRasGAP

RASA4 RASA4B

2.26e-0315892PF00616
DomainRAS_GTPASE_ACTIV_1

RASA4 RASA4B

2.26e-0315892PS00509
DomainRAS_GTPASE_ACTIV_2

RASA4 RASA4B

2.26e-0315892PS50018
Domain-

RASA4 RASA4B

2.58e-03168921.10.506.10
DomainRasGAP_dom

RASA4 RASA4B

3.27e-0318892IPR001936
DomainGPCR_3

CASR GRM8

4.45e-0321892IPR000337
DomainGPCR_Rhodpsn_7TM

OR2B11 HCAR2 DRD4 OR13C5 OR6C2 CCR6 OR10J1 OR10X1 FFAR4

4.61e-03670899IPR017452
Domain7tm_3

CASR GRM8

4.87e-0322892PF00003
DomainG_PROTEIN_RECEP_F3_2

CASR GRM8

4.87e-0322892PS00980
DomainG_PROTEIN_RECEP_F3_3

CASR GRM8

4.87e-0322892PS00981
DomainG_PROTEIN_RECEP_F3_1

CASR GRM8

4.87e-0322892PS00979
DomainG_PROTEIN_RECEP_F3_4

CASR GRM8

4.87e-0322892PS50259
DomainGPCR_3_C

CASR GRM8

4.87e-0322892IPR017978
Domain7tm_1

OR2B11 HCAR2 DRD4 OR13C5 OR6C2 CCR6 OR10J1 OR10X1 FFAR4

4.93e-03677899PF00001
DomainAAA+_ATPase

ATAD2B CFTR FIGN RFC5

4.99e-03144894IPR003593
DomainAAA

ATAD2B CFTR FIGN RFC5

4.99e-03144894SM00382
DomainG_PROTEIN_RECEP_F1_1

OR2B11 HCAR2 DRD4 OR13C5 OR6C2 CCR6 OR10J1 OR10X1 FFAR4

5.31e-03685899PS00237
DomainG_PROTEIN_RECEP_F1_2

OR2B11 HCAR2 DRD4 OR13C5 OR6C2 CCR6 OR10J1 OR10X1 FFAR4

5.62e-03691899PS50262
DomainGPCR_Rhodpsn

OR2B11 HCAR2 DRD4 OR13C5 OR6C2 CCR6 OR10J1 OR10X1 FFAR4

5.67e-03692899IPR000276
Pubmed

CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.

RASA4 RASA4B

6.48e-06289211448776
Pubmed

A critical role for the histidine residues in the catalytic function of acyl-CoA:cholesterol acyltransferase catalysis: evidence for catalytic difference between ACAT1 and ACAT2.

SOAT2 SOAT1

6.48e-06289216647063
Pubmed

Organization of human ACAT-2 gene and its cell-type-specific promoter activity.

SOAT2 SOAT1

6.48e-06289211401500
Pubmed

Gender specific hippocampal whole genome transcriptome data from mice lacking the Cav2.3 R-type or Cav3.2 T-type voltage-gated calcium channel.

CACNA1E CACNA1H

6.48e-06289228393090
Pubmed

Quantitative analysis of the expression of ACAT genes in human tissues by real-time PCR.

SOAT2 SOAT1

6.48e-06289214729857
Pubmed

Investigating the allosterism of acyl-CoA:cholesterol acyltransferase (ACAT) by using various sterols: in vitro and intact cell studies.

SOAT2 SOAT1

6.48e-06289215992359
Pubmed

Non-Mendelian inheritance during inbreeding of Cav3.2 and Cav2.3 deficient mice.

CACNA1E CACNA1H

6.48e-06289233009476
Pubmed

Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism.

SOAT2 SOAT1

6.48e-06289226982734
Pubmed

Two separate Ni(2+) -sensitive voltage-gated Ca(2+) channels modulate transretinal signalling in the isolated murine retina.

CACNA1E CACNA1H

6.48e-06289221883984
Pubmed

Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT).

SOAT2 SOAT1

6.48e-06289218000807
Pubmed

Expression of two isozymes of acyl-coenzyme A: cholesterol acyltransferase-1 and -2 in clear cell type renal cell carcinoma.

SOAT2 SOAT1

6.48e-06289218269457
Pubmed

Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine.

SOAT2 SOAT1

6.48e-06289222811412
Pubmed

The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR.

CFTR CASR

6.48e-06289226911344
Pubmed

An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.

RASA4 RASA4B

6.48e-06289216041389
Pubmed

The influence of the acyl-CoA:cholesterol acyltransferase-1 gene (-77G-->A) polymorphisms on plasma lipid and apolipoprotein levels in normolipidemic and hyperlipidemic subjects.

SOAT2 SOAT1

6.48e-06289215158756
Pubmed

Ability of serum to decrease cellular acylCoA:cholesterol acyl transferase activity predicts cardiovascular outcomes.

SOAT2 SOAT1

6.48e-06289216230498
Pubmed

Impaired cholesterol metabolism in the mouse model of cystic fibrosis. A preliminary study.

CFTR SOAT2

6.48e-06289233412572
Pubmed

Localization of the mouse glucocorticoid receptor-interacting protein 1 gene (Grip1) to proximal chromosome 1 by linkage analysis.

CPS1 SOAT1 CHRND

1.07e-05178939250876
Pubmed

Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes.

SOAT2 SOAT1

1.94e-0538929756920
Pubmed

CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.

RASA4 RASA4B

1.94e-05389225637021
Pubmed

Molecular mechanisms of calcium-sensing receptor-mediated calcium signaling in the modulation of epithelial ion transport and bicarbonate secretion.

CFTR CASR

1.94e-05389225331955
Pubmed

ACAT2 and ABCG5/G8 are both required for efficient cholesterol absorption in mice: evidence from thoracic lymph duct cannulation.

SOAT2 SOAT1

3.87e-05489222669916
Pubmed

Cellular pregnenolone esterification by acyl-CoA:cholesterol acyltransferase.

SOAT2 SOAT1

3.87e-05489222474282
Pubmed

HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability.

ATR USP20

3.87e-05489225326330
Pubmed

ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD.

SOAT2 SOAT1

3.87e-05489220133765
Pubmed

Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells.

SOAT2 SOAT1

3.87e-05489215308631
Pubmed

Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding.

RASA4 RASA4B

3.87e-05489216234249
Pubmed

Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.

RASA4 RASA4B

3.87e-05489221460216
Pubmed

LMO4 is essential for paraventricular hypothalamic neuronal activity and calcium channel expression to prevent hyperphagia.

CACNA1E CACNA1H

3.87e-05489224381275
Pubmed

Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice.

CACNA1E CACNA1H

6.44e-05589212060068
Pubmed

Pias1 interaction and sumoylation of metabotropic glutamate receptor 8.

GRM8 PIAS2

9.65e-05689216144832
Pubmed

Prediction of genetic risk for dyslipidemia.

CYP3A4 SOAT2

9.65e-05689217919884
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

CACNA1E ATP5PO CORO1C DNAJC11 CFTR RNF222 CRMP1

1.21e-0443089732581705
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1E CACNA1H

1.35e-04789212900400
Pubmed

Cloning of 5'-flanking region and a polymorphic CTT trinucleotide repeat within 5'-untranslated region of mouse R-type calcium channel alpha1-subunit (Cchra1) gene, and its genetic mapping.

CACNA1E SOAT1

1.35e-0478929651528
Pubmed

ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization.

SOAT2 SOAT1

1.79e-0488929756919
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1E CACNA1H

1.79e-04889228330839
Pubmed

Comparative genome mapping in the sequence-based era: early experience with human chromosome 7.

RASA4 RASA4B

1.79e-04889210810084
Pubmed

Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6.

A2M LRP6

1.79e-04889216384981
Pubmed

Chemerin, a novel adipokine in the regulation of angiogenesis.

GRM8 OR10J1

1.79e-04889220237162
Pubmed

Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver.

CYP3A4 CASR

1.79e-04889218794335
Pubmed

Akt and 14-3-3eta regulate Miz1 to control cell-cycle arrest after DNA damage.

CDKN1C PIAS2

1.79e-04889215580267
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1E CACNA1H

2.30e-04989216382099
Pubmed

LDL-receptor-related protein 6 is a receptor for Dickkopf proteins.

SPTBN2 LRP6

2.30e-04989211357136
Pubmed

BRCA1-mediated chromatin silencing is limited to oocytes with a small number of asynapsed chromosomes.

SYCP2 ATR

2.30e-04989219531582
Pubmed

Exocrine glands and the Chievitz organ of some mouse mutants.

LRP6 FIGN

2.30e-0498925088022
Pubmed

Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes.

PAH CPS1 SOAT1 CHRND

2.71e-041218948827514
Pubmed

Wnt signaling mutants have decreased dentate granule cell production and radial glial scaffolding abnormalities.

LRP6 EPHA1

2.88e-041089214715945
Pubmed

The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids.

CASR GRM8

2.88e-041089217156446
Pubmed

Liver maturation deficiency in p57(Kip2)-/- mice occurs in a hepatocytic p57(Kip2) expression-independent manner.

CDKN1C CYP3A4

2.88e-041089226165599
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

VWA5B2 SEMA4F CACNA1E PCDH11X SLCO6A1

3.40e-0423389537704626
Pubmed

Partial loss of Ascl2 function affects all three layers of the mature placenta and causes intrauterine growth restriction.

CDKN1C ERVW-1

4.20e-041289221238448
Pubmed

Human metabolic individuality in biomedical and pharmaceutical research.

CYP3A4 CPS1 KLKB1

4.29e-045789321886157
Pubmed

Meiotic failure in male mice lacking an X-linked factor.

SYCP2 ATR

4.96e-041389218316482
Pubmed

Identification of proteins interacting with the mitochondrial small heat shock protein Hsp22 of Drosophila melanogaster: Implication in mitochondrial homeostasis.

ATP5PO DNAJC11 CPS1 VARS1

5.52e-0414689429509794
Pubmed

Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors.

A2M CPS1

5.78e-041489216103213
Pubmed

TRIM28 functions as the SUMO E3 ligase for PCNA in prevention of transcription induced DNA breaks.

RECQL5 PIAS2

6.65e-041589232900933
Pubmed

Pancreatitis Overview

CFTR CASR

6.65e-041589224624459
Pubmed

Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.

DRD4 IMMP2L GRM8

6.89e-046789320398908
Pubmed

Tie2 regulates endocardial sprouting and myocardial trabeculation.

CDKN1C MYH11 TIE1

7.20e-046889331112136
Pubmed

Genetic susceptibility to distinct bladder cancer subphenotypes.

CDKN1C DRD4 CYP3A4 LRP6 CASR SOAT2

7.57e-0442189619692168
Pubmed

Modifier genes in mice and humans.

CFTR FIGN

7.59e-041689211256068
Pubmed

Which DNA polymerases are used for DNA-repair in eukaryotes?

POLE2 RFC5

7.59e-04168929111189
Pubmed

Deficiency in the secreted protein Semaphorin3d causes abnormal parathyroid development in mice.

CDKN1C CASR

7.59e-041689230979723
Pubmed

Fetal growth restriction in a genetic model of sporadic Beckwith-Wiedemann syndrome.

CDKN1C ERVW-1

7.59e-041689230158284
Pubmed

Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.

HCAR2 DRD4 CCR6

9.57e-04758932834384
Pubmed

The DNA sequence of human chromosome 7.

ZNF277 RASA4 RASA4B ERVW-1 IMMP2L EPHA1

9.62e-0444189612853948
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

FOXK2 ATAD2B RECQL5 BCOR RFC5 SGO1 PIAS2

9.64e-0460889736089195
Pubmed

Fetal overgrowth in the Cdkn1c mouse model of Beckwith-Wiedemann syndrome.

CDKN1C ERVW-1

9.65e-041889221729874
Pubmed

Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.

CDKN1C ATR CYP3A4 F13A1

9.74e-0417089419064572
Pubmed

Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse.

PAH CPS1 CHRND

9.95e-04768938288233
Pubmed

Loss of mouse Ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKBKAP.

CDKN1C TIE1

1.32e-032189219015235
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ERGIC1 FOXK2 ATP5PO ZNF277 CORO1C DNAJC11 SYNGR2 RECQL5 BCOR RFC5 VARS1

1.52e-031497891131527615
Pubmed

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

DRD4 CYP3A4 SOAT2 SOAT1

1.52e-0319289420602615
Pubmed

Identification of proteins interacting with protein arginine methyltransferase 8: the Ewing sarcoma (EWS) protein binds independent of its methylation state.

RASA4 CPS1

1.58e-032389218320585
Pubmed

High-density polymorphisms analysis of 23 candidate genes for association with bone mineral density.

CYP3A4 CASR

1.58e-032389220654748
Pubmed

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.

CDKN1C ATR CASR CCR6 F13A1

1.64e-0333189520634891
Pubmed

Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.

CDKN1C CASR

1.72e-032489220705733
Pubmed

Proteomic analysis of the palmitoyl protein thioesterase 1 interactome in SH-SY5Y human neuroblastoma cells.

ATP5PO CRMP1

1.72e-032489225865307
Pubmed

Genetic determinants influencing human serum metabolome among African Americans.

CPS1 KLKB1

1.72e-032489224625756
Pubmed

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.

A2M MYH11 SPTBN2

1.73e-039289337343697
Pubmed

NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy.

CORO1C SPTBN2

1.87e-032589230309841
Pubmed

Intermediate phenotypes identify divergent pathways to Alzheimer's disease.

CALHM1 PCDH11X

1.87e-032589220574532
Pubmed

Mab21l2 is essential for embryonic heart and liver development.

CDKN1C TIE1

1.87e-032589222412967
Pubmed

Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation.

CDKN1C MYH11

2.18e-032789224335256
Pubmed

Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.

TIE1 EPHA1

2.34e-032889218593464
CytobandEnsembl 112 genes in cytogenetic band chr7q31

ZNF277 CFTR IMMP2L GRM8

1.65e-04140894chr7q31
CytobandEnsembl 112 genes in cytogenetic band chr7q22

TMEM130 CYP3A4 RASA4 RASA4B

8.96e-04219894chr7q22
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA4 RASA4B

5.12e-0410622830
GeneFamilyAAA ATPases

ATAD2B FIGN RFC5

7.96e-0453623413
GeneFamilyFibronectin type III domain containing

IL31RA DSCAM TIE1 EPHA1

2.21e-03160624555
GeneFamilyCalcium voltage-gated channel subunits

CACNA1E CACNA1H

3.57e-0326622253
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN8 A2M SYCP2 CFTR PCDH11X CPS1 FIGN

8.19e-081848872cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN8 A2M SYCP2 CFTR PCDH11X CPS1 FIGN

8.19e-08184887ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN8 A2M SYCP2 CFTR PCDH11X CPS1 FIGN

8.19e-081848872b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 TMEM130 RASA4 RASA4B CALHM4 FFAR4

1.41e-06177886c80893e5cf5688ee9f5afc8f11b3890f296c9e1f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

HCAR2 LPCAT1 RNF212 RASA4B FFAR4

4.24e-06121885b6dada0712b1f9793bc61e54ec7f10c9eaf53b86
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CAPN8 IL31RA RNF212 SAMD3

1.14e-0570884677deb7c7c100756a4cdc788d61feb45039a9a97
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCR6 CEP76 RFC5 SGO1 CRMP1

2.15e-05169885dbf9b1d52b29bf4b60bd23012cc1ea82d344747f
ToppCell368C-Lymphocytic-ILC|368C / Donor, Lineage, Cell class and subclass (all cells)

MYH11 FOXK2 UBE3D BCOR EPHA1

2.27e-051718853b3143e4aa6520ee9c6b6f2482206ad3d8205d14
ToppCell368C-Lymphocytic-ILC-ILC-2|368C / Donor, Lineage, Cell class and subclass (all cells)

MYH11 FOXK2 UBE3D BCOR EPHA1

2.27e-05171885fd01076574dcc82bfd4a1538812500543b16794f
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM151B CDKN1C PTPDC1 TIE1 KLKB1

2.40e-0517388585083b9ce20351dd69aa2327ad087b848b4307ff
ToppCellIonocyte-iono-2|World / Class top

CDKN1C SYCP2 RASA4 CFTR SOAT1

2.40e-05173885e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M MYH11 CACNA1H FIGN C2orf72

2.75e-05178885185b44700f06ec58b3c09c80520502166c965fd6
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M TIE1 RASA4 MYRIP RASA4B

2.75e-05178885aa44851653d276226b922ee14dd1fc8d1a844cdf
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LPCAT1 CFTR RNF180 KLKB1 SOAT1

2.83e-05179885bf012825e88626e59cd1deebf67c2cd269ce4829
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM CACNA1H GRM8 FFAR4 CRMP1

2.90e-051808850677bf4a5177d9cbc6716195bd966eeae8de2f31
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma|TCGA-Prostate / Sample_Type by Project: Shred V9

ERGIC1 SYNGR2 SPTBN2 VARS1 C2orf72

3.48e-05187885fa0452f3382c22c0391b241d06504fda3c6a19f0
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

VWA5B2 CACNA1E DSCAM GRM8 FFAR4

3.48e-0518788598477ba04a42a8da80a72f41a182429f46283595
ToppCellTCGA-Prostate-Primary_Tumor|TCGA-Prostate / Sample_Type by Project: Shred V9

ERGIC1 SYNGR2 SPTBN2 VARS1 C2orf72

3.48e-051878853e6a95c912dad5d61e10497ffaafd2b9027cd13a
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

A2M SYNGR2 CCR6 F13A1 FFAR4

3.57e-051888859fc3819aae5a2b2534cb131d467435b5cfc420d6
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

A2M SYNGR2 CCR6 F13A1 FFAR4

3.57e-051888855e5d779ea079d3b2a1ef650b06b9f5cc1ffef5e7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M TIE1 APCDD1 PCDH11X SLC5A4

3.66e-051898856463890d8dbee4bc198f91628a5f784970de786a
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

CAPN8 TMEM130 OR6C2 CFTR CASR

3.76e-05190885756bff697d30aec56c0ebfca94295f084a15bf37
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M TIE1 APCDD1 PCDH11X SLC5A4

3.95e-05192885bacbaef1f230051335f4433e55db07a161b96b4c
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LVRN PTPDC1 CYP3A4 MYRIP KLKB1

3.95e-05192885d6f656be2698bd215717d35f4e7ab727c08c61e0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M TIE1 PCDH11X MYRIP SLC5A4

4.05e-051938852e72309607902dabe3218888b22a77fe941f3570
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

A2M MYH11 CDC42EP2 CACNA1H CRMP1

4.15e-051948858f19e553f18c313c2a2ff9453884b9484b255d71
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

A2M MYH11 CDC42EP2 CACNA1H CRMP1

4.15e-0519488567fbb81b7d20cb63be27b2a2beea5b5689f8e08c
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

A2M TIE1 RASA4 MYRIP RASA4B

4.25e-0519588581a98ebb0d43f416f9a8bba580531dc0cfea8f74
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

A2M MYH11 SYNGR2 CACNA1H RNF180

4.46e-0519788571367bebc23d0e81f60f780d6b0ab3a1783ac014
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

A2M MYH11 SYNGR2 CACNA1H RNF180

4.46e-051978850f9836554ace3f9d155ebafdd719aa26466ca44e
ToppCellIPF-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

A2M RASA4 MYRIP RASA4B DENND5A

4.57e-05198885b8bd1ba268480f54451648e01631b615a3401144
ToppCellwk_08-11-Epithelial-Proximal_epithelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

VWA5B2 CAPN8 HCAR2 RASA4B FFAR4

4.57e-051988859895f1d65d18d939f3974a914ee41c6d5575e765
ToppCellIonocyte-iono-4|World / Class top

LPCAT1 POLE2 CEP76 F13A1

1.25e-0412988485ee6e16959cb58a58f5b09edf1f78d9ce6a9441
ToppCellPND07-28-samps-Lymphocyte-B_cell-B_cell_2|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CACNA1E MYRIP SLX4IP CACNA1H

1.57e-041378842544d1256f11da6e3bad24a871b2253e0ab20d01
ToppCellPND07-28-samps-Lymphocyte-B_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CACNA1E MYRIP SLX4IP CACNA1H

1.57e-04137884874e2eaa7846a2832f46b77c726d79f220a4a1cd
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Smooth_Muscle-like_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

CACNA1E MYH11 SPTBN2 PCDH11X

1.71e-041408845623a0a68403fc00166b7d13d13e184a718d9bdd
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1E POLE2 SGO1 SOAT2

1.90e-04144884013223bb2f31eb5bebdbd0908b797d28b96c6f7b
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Tcf7l2_(Substantia_Innominata_(SI))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CAPN8 IL31RA RNF212

1.96e-0457883eab63d89e2100bb94fb026f700c2f82d657f92c1
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Tcf7l2_(Substantia_Innominata_(SI))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CAPN8 IL31RA RNF212

1.96e-04578832dc04513910af16d2cd84b3ae5b8d4c831124c68
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HCAR2 RFC5 SGO1 F13A1

2.01e-0414688445d7cb73776e60d22f335a651845e21e16948fcc
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FAM151B CDKN1C RASA4B F13A1

2.17e-04149884a85a051e0d82430160967e72fa04b55f43e84513
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175|Adult / Lineage, Cell type, age group and donor

CAPN8 CFTR MYRIP PCCB

2.23e-04150884b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FAM151B CDKN1C RASA4B F13A1

2.23e-041508847a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT1 MYH11 MYRIP CCR6

2.34e-04152884d5ba87b5d34e52cef8475befafea962d70fa8a1d
ToppCelldroplet-Liver-LIVER_HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT1 MYH11 MYRIP CCR6

2.34e-04152884d88d68a788a3256671ebbc06e104833f1f58f07d
ToppCellP15-Epithelial-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LPCAT1 CFTR FIGN SOAT1

2.34e-0415288400d5503d462cfa009fb4cac79ecee11725a18b9a
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial-Progenitor_(NEUROG3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 RASA4 CHRND FFAR4

2.40e-0415388420786807bba3bcd70ce744f8b6454e064199ed9f
ToppCellremission-unassigned|remission / disease stage, cell group and cell class

A2M CACNA1H CCR6 IMMP2L

2.46e-041548844130769829b838cc8a075c87ff6c187f0f507f8b
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT2_Precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

SEMA4F LPCAT1 CFTR CPS1

2.52e-041558849cad73d0b8ead289e1073d1a2e00bbeb1228308c
ToppCellremission-unassigned|World / disease stage, cell group and cell class

A2M CACNA1H CCR6 IMMP2L

2.52e-04155884d81bec894381e3e2d6249a567e8108b8423e5c54
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E SLX4IP IRGC GRM8

2.65e-04157884fc127e7720649e746f3d3f5c2e9e63784767106a
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E SLX4IP IRGC GRM8

2.65e-0415788466a191cef4aa00811bb04462310d012610006f85
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F RFC5 SGO1 SOAT2

2.71e-04158884ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E IRGC IMMP2L VARS1

2.71e-0415888466c011e9de002224f70725dfe8e7871c8d304492
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCYL2 AMIGO3 F13A1 EPHA1

2.78e-04159884999f30c7273ed77b34537621bcfcc7fc30121138
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 RASA4 CHRND FFAR4

2.85e-041608846c89a2e4189e4f2b6b09b66c6aae6653785ab2f8
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN8 MYH11 CFTR CPS1

2.85e-04160884c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E SYNGR2 IRGC CCR6

2.85e-041608846bafbe2b4b98bc088406a516d079093f89d9c344
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN8 MYH11 CFTR CPS1

2.85e-0416088425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1E IRGC IMMP2L VARS1

2.92e-041618847af3b0d4fc7967f6b3e2d255d23fd8b1fd01a7af
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1E IRGC IMMP2L VARS1

2.92e-0416188498be0cf8228496b31f7f3e0efd8787e95eb626d1
ToppCelldroplet-Limb_Muscle-nan-18m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM151B AMIGO3 KLKB1 F13A1

2.98e-0416288471d7849108a1b59beff40e46000172c45a2f5439
ToppCelldroplet-Heart-nan-18m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F SGO1 FFAR4 C2orf72

2.98e-041628847f425a3983325a5a3ea33f812b15aa010cc55de0
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M TIE1 MYRIP SLC5A4

3.06e-04163884977a970b1296234c22178420294cea73506ee02f
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M TIE1 MYRIP SLC5A4

3.06e-04163884ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERGIC1 AMIGO3 CACNA1H SGO1

3.13e-04164884b92e7c91910d518627376166c6ea9ed333b3d07e
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERGIC1 AMIGO3 CACNA1H SGO1

3.13e-04164884a1e43c6b3e2553f5604100db6e92bf244b70c36d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DSCAM SLC26A7 SPTBN2 CFTR

3.20e-041658849bd332e5ede759a00a47728ea5558c215efdd77a
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRGC RNF180 GRM8 F13A1

3.20e-041658848a52f2dbcbd2bc1662b5e3fac381463fdcc3bf14
ToppCellEndothelial-endothelial_cell_of_bronchial_vessel|World / Lineage, Cell type, age group and donor

A2M TIE1 MYRIP SLC5A4

3.20e-0416588484e553d699ac56df89a77248f7308b9133e1b683
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 DRD4 PAH RASA4B

3.27e-04166884eb9c81fa7573de7aff6670e7dad313f02129809f
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYH11 CEP76 SAMD3 SOAT2

3.27e-0416688426f3d5e5e30b63b09b89cda23c423d12d887631f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

APCDD1 POLE2 LRP6 BCOR

3.27e-04166884c8fd241088de27c6e741a5dfee3cd770183b6bcb
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RECQL5 IRGC GRM8 USP20

3.35e-04167884e0f2509e86302eca8352821bce12597f6c51fc24
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E LPCAT1 MYH11 CCR6

3.35e-04167884e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

VWA5B2 CACNA1E CACNA1H CRMP1

3.35e-04167884c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCellfacs-Lung-EPCAM-24m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RECQL5 IRGC GRM8 USP20

3.35e-04167884b25646b6653cd8814dbeae4c74ce899ede105200
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 CAPN8 A2M CCR6

3.35e-04167884691f3589de0f8c13f9137812cfa9040c07d237b4
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

A2M SYCP2 RECQL5 EPHA1

3.50e-0416988416c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCelldroplet-Lung-nan-3m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F POLE2 RFC5 CRMP1

3.50e-04169884df2c9c706bfc9db2bc5726602a49f5f5a94e9481
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|390C / Donor, Lineage, Cell class and subclass (all cells)

RASA4 POLE2 CCR6 EPHA1

3.50e-04169884cfc9ff103d13a2d5eacc457e800f53fdd29f7738
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F POLE2 RFC5 CRMP1

3.50e-04169884f6a6d2f614d60395ad9b867ff1cf59eba72b04ce
ToppCellP07-Epithelial-epithelial_progenitor_cell-epi_progenitor|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LPCAT1 CFTR RFC5 SOAT1

3.50e-041698841a47a4892a5e6a69555f5332308503526e5422a7
ToppCellP03-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEMA4F LPCAT1 CFTR SOAT1

3.58e-041708843fd37e9b377d6485cea1262c31a8507d18a78514
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWA5B2 TMEM130 CASR CRMP1

3.58e-04170884941d637cf76918ee4b0a1833abd1a42593cb8b1a
ToppCellTCGA-Cervix|World / Sample_Type by Project: Shred V9

SYCP2 POLE2 RNF212 RFC5

3.58e-04170884a6cbe253bc60f5d5cb361c7e85ed9928a3155ec8
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F SLX4IP CCR6 CRMP1

3.66e-04171884246fc7edcefc47437d1df6029f295aca3b34b2b2
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M TIE1 RASA4 MYRIP

3.66e-04171884b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F SLX4IP CCR6 CRMP1

3.66e-041718841fb4e11f92b48dc2d6e553c22e2571bbd8c223c6
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CAPN8 CFTR RNF212 PCDH11X

3.75e-04172884adc09c4d1b63fe84150516beb692db1e7f7ac980
ToppCelldroplet-Spleen-nan-21m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM RASA4 SYNGR2 FFAR4

3.75e-041728844fe5b91e4871bc6c5be57eb5b8bb04815b2fb80d
ToppCellfacs-BAT-Fat-3m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8B1 RASA4 F13A1 SOAT1

3.75e-041728845f18c3f8eb8b7928901eede44c9b84b3c5efa1a9
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

FOXK2 SLX4IP FFAR4 EPHA1

3.75e-04172884da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCell10x5'-Lung-Lymphocytic_NK-Cycling_NK|Lung / Manually curated celltypes from each tissue

SLC26A7 CALHM1 RFC5 SGO1

3.83e-04173884d815832f89f70662706620e3b03ebb1dabec0034
ToppCellfacs-Marrow-T_cells-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERGIC1 CACNA1H FIGN CHRND

3.83e-04173884e0cf99ddbe6e9eab05d7bf89e9aa124850c6a807
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC8B1 PAH SAMD3 GRM8

3.83e-041738848ac2e9d39c0f76e674f8bd59d1da246bab4867c8
ToppCellE17.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEMA4F LPCAT1 CFTR SOAT1

3.91e-0417488468914ec843f58ecff3e6412544a341daf8a01cac
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 CACNA1E CASR FFAR4

3.91e-041748843503c7dec498597f76a86dbd5e4bb2311e743bde
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 SLC26A7 CASR CACNA1H

3.91e-041748849f114e61458659005b6d0b4aa30a7a059e7aa5c6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LVRN A2M DAND5 SLC5A4

3.91e-041748843d4c05ea5719ca65e85d1f15198453034791087c
DrugPyrimidinones

HCAR2 CYP3A4 CASR

2.23e-074883ctd:D011744
Drugcetyl ether

A2M SOAT2 SOAT1

4.61e-069883CID000077757
DrugPD138142-15

CYP3A4 SOAT2 SOAT1

4.61e-069883CID003025787
Drugetiroxate

CYP3A4 SOAT2 SOAT1

9.00e-0611883CID000065683
Drugetofibrate

CYP3A4 SOAT2 SOAT1

1.20e-0512883CID000065777
DrugAC1Q6A3R

SOAT2 SOAT1

1.48e-052882CID000160583
Druggypsetin

SOAT2 SOAT1

1.48e-052882CID000160406
Drugglisoprenin B

SOAT2 SOAT1

1.48e-052882CID006438769
DrugNSC292654

SOAT2 SOAT1

1.48e-052882CID000325064
Drug23-methyl-UDCA

SOAT2 SOAT1

1.48e-052882CID000196679
Drug7,7-difluorocholestanol

SOAT2 SOAT1

1.48e-052882CID000196646
Drug6,6-difluorocholestanol

SOAT2 SOAT1

1.48e-052882CID000196647
DrugAplus

SOAT2 SOAT1

1.48e-052882CID000028221
DrugRo 16-0521

SOAT2 SOAT1

1.48e-052882CID000065657
DrugAC1NT076

SOAT2 SOAT1

1.48e-052882CID005321102
Drugxymedon

SOAT2 SOAT1

1.48e-052882CID000121931
DrugApal

CDKN1C PAH CASR

2.45e-0515883CID003082547
Drugclinofibrate

LPCAT1 SOAT2 SOAT1

3.65e-0517883CID000002787
Drughomovanillic acid

CDKN1C CACNA1E DRD4 PAH CACNA1H

3.75e-0597885CID000001738
Drugglisoprenin A

SOAT2 SOAT1

4.42e-053882CID006438768
DrugL-Valine

PCCB VARS1

4.42e-053882DB00161
Drugolean-12-ene

SOAT2 SOAT1

4.42e-053882CID000612780
DrugPurpactin A

SOAT2 SOAT1

4.42e-053882CID000131673
DrugNsc692258

SOAT2 SOAT1

4.42e-053882CID000469167
Drugethyl 6-chlorochroman-2-carboxylate

SOAT2 SOAT1

4.42e-053882CID000169516
Drugzaragozic acid D3

SOAT2 SOAT1

4.42e-053882CID006475792
Drugnefiracetam

CACNA1E HCAR2 CYP3A4 CHRND

6.56e-0556884CID000071157
DrugCgs-26214

SOAT2 SOAT1

8.82e-054882CID000133077
Drugisochromophilone VII

SOAT2 SOAT1

8.82e-054882CID006443571
Drugisochromophilone VIII

SOAT2 SOAT1

8.82e-054882CID006443572
Drugacaterin

SOAT2 SOAT1

8.82e-054882CID000126830
DrugAC1L3QAA

SOAT2 SOAT1

8.82e-054882CID000093484
Drug1,3-di-o-tolylguanidine

A2M CACNA1E DRD4 ERVW-1

9.19e-0561884CID000007333
DrugCI-976

LPCAT1 SOAT2 SOAT1

9.34e-0523883CID000122327
Drugdalcetrapib

CYP3A4 SOAT2 SOAT1

9.34e-0523883CID006918540
Drugmorphine hydrochloride

CDKN1C CACNA1E DRD4 CYP3A4 CFTR PAH CACNA1H CCR6 GRM8

1.01e-04481889CID000004253
DrugSelegiline hydrochloride [14611-52-0]; Up 200; 17.8uM; MCF7; HT_HG-U133A

A2M RECQL5 CASR CACNA1H GRM8 F13A1

1.04e-041938864146_UP
DrugMeclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; PC3; HT_HG-U133A

CDKN1C SYCP2 ZNF277 ATAD2B CDC42EP2 GRM8

1.14e-041968866637_DN
DrugProtoveratrine A [143-57-7]; Up 200; 5uM; MCF7; HT_HG-U133A

CDKN1C CYP3A4 F13A1 SOAT2 CRMP1 C2orf72

1.14e-041968862800_UP
DrugIsoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A

A2M SPTBN2 LRP6 CACNA1H CPS1 CRMP1

1.20e-041988864789_UP
DrugEtomidate [33125-97-2]; Up 200; 16.4uM; MCF7; HT_HG-U133A

SYCP2 CDC42EP2 PIAS2 SOAT2 EPHA1 C2orf72

1.24e-041998867460_UP
DrugFinasteride [98319-26-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A

A2M ZNF277 CFTR CDC42EP2 CACNA1H GRM8

1.24e-041998863641_DN
DrugBrompheniramine maleate [980-71-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A

CDKN1C DSCAM SPTBN2 CDC42EP2 OR10J1 CRMP1

1.24e-041998863271_UP
DrugLetrozole [112809-51-5]; Up 200; 14uM; MCF7; HT_HG-U133A

SYCP2 CFTR LRP6 CACNA1H EPHA1 PMM1

1.24e-041998867336_UP
Drugpimozide

CACNA1E DRD4 CYP3A4 CACNA1H EPHA1

1.35e-04127885CID000016362
Drugdihydroisocoumarin

CYP3A4 PAH

1.47e-045882CID000078429
DrugNSC-110264

SOAT2 SOAT1

1.47e-045882CID000269324
DrugAC1L2AC7

CACNA1E CACNA1H SOAT2 SOAT1

1.49e-0469884CID000068733
Diseasecholesteryl ester 24:0 measurement

SYCP2 SOAT2

4.67e-054832EFO_0021445
Diseaseintellectual disability (is_implicated_in)

DRD4 PAH CASR

8.25e-0530833DOID:1059 (is_implicated_in)
Diseaseentorhinal cortical volume

UBE3D F13A1

1.16e-046832EFO_0005092
DiseaseHereditary pancreatitis

CFTR CASR

1.63e-047832C0238339
Diseasecholesteryl ester 24:4 measurement

SOAT2 SOAT1

1.63e-047832EFO_0021447
DiseaseSchizophrenia

CDKN1C HCAR2 DRD4 SLC26A7 CYP3A4 SPTBN2 PAH ERVW-1 GRM8 CRMP1

1.85e-048838310C0036341
Diseasealpha-2-macroglobulin measurement

A2M KLKB1

2.16e-048832EFO_0020138
Diseasepeptidyl-glycine alpha-amidating monooxygenase measurement

LVRN KLKB1

4.23e-0411832EFO_0801871
Diseasecholesteryl ester 24:5 measurement

SOAT2 SOAT1

5.07e-0412832EFO_0021448
Diseasephenylalanine measurement

PAH CPS1 KLKB1

5.07e-0455833EFO_0005001
DiseaseProteinuria

FAM151B SAMD3

8.02e-0415832HP_0000093
Diseasetumor necrosis factor beta measurement

OR2B11 IMMP2L

8.02e-0415832EFO_0008308
Diseaseesophageal adenocarcinoma

PTPDC1 CFTR

1.16e-0318832EFO_0000478
Diseaseserum homoarginine measurement

CPS1 CRMP1

1.44e-0320832EFO_0005421
Diseaseattention deficit hyperactivity disorder (is_implicated_in)

DRD4 GRM8

1.44e-0320832DOID:1094 (is_implicated_in)
DiseaseAttention Deficit Disorder

DRD4 GRM8

1.74e-0322832C0041671
DiseaseMinimal Brain Dysfunction

DRD4 GRM8

1.74e-0322832C1321905
DiseaseAttention deficit hyperactivity disorder

DRD4 GRM8

2.07e-0324832C1263846
Diseasenephrotic syndrome (biomarker_via_orthology)

A2M SOAT2

2.07e-0324832DOID:1184 (biomarker_via_orthology)
DiseaseFEV change measurement, response to zileuton

CCR6 CPS1

2.25e-0325832EFO_0005921, EFO_0007676
Diseasewaist-hip ratio

PTPDC1 HCAR2 DAND5 MYH11 FOXK2 APCDD1 CFTR FIGN PCCB FFAR4

2.29e-0312268310EFO_0004343
DiseaseL-arginine measurement

CPS1 KLKB1

2.62e-0327832EFO_0006524
DiseaseAcute Confusional Senile Dementia

A2M PCDH11X EPHA1

2.77e-0399833C0546126
DiseaseAlzheimer's Disease, Focal Onset

A2M PCDH11X EPHA1

2.77e-0399833C0750900
DiseaseAlzheimer Disease, Early Onset

A2M PCDH11X EPHA1

2.77e-0399833C0750901
DiseasePresenile dementia

A2M PCDH11X EPHA1

2.77e-0399833C0011265
DiseaseAlzheimer Disease, Late Onset

A2M PCDH11X EPHA1

2.77e-0399833C0494463

Protein segments in the cluster

PeptideGeneStartEntry
CVALVSVRVFYQRCP

EPHA1

191

P21709
ARTVDRLCLFVVTPV

CHRND

466

Q07001
SFCIVLRMAVTRQFP

CFTR

341

P13569
AIRSPLVFVLCRASS

C2orf72

101

A6NCS6
IPVRQNCFTVNRSLF

CACNA1E

56

Q15878
TCRLRQPAFGISFVL

CASR

676

P41180
CSLQEVRQFSRLFVP

CCR6

36

P51684
SSFCAVNPRFVAIII

CORO1C

36

Q9ULV4
TLLAFVVRSVRPCFT

CALHM1

196

Q8IU99
VVRSVRPCFTQAAFL

CALHM1

201

Q8IU99
QRVPFSVFTTNPCRI

POLE2

391

P56282
FVRQFSRLEICNLSP

CAPN8

331

A6NHC0
LAVRVRVFTYPESAC

CEP76

631

Q8TAP6
CLAFKVPASRVRFFQ

AMIGO3

251

Q86WK7
PFTGRVNITVRCTVA

LVRN

126

Q6Q4G3
SSRIFRCNFPNVEIV

BCOR

1676

Q6W2J9
RQVRCFSTSVVRPFA

ATP5PO

11

P48047
RVTAAPQSVCALRAV

A2M

586

P01023
VRACPAVVRATFRQL

RASA4

431

O43374
FLEVSFTTVCIPRFL

OR6C2

66

Q9NZP2
VRACPAVVRATFRQL

RASA4B

431

C9J798
VAVPVAVTFLDRVAC

IMMP2L

21

Q96T52
FVQVFSRPGCSAIRL

DAND5

106

Q8N907
FLVARCRQPSVIFVS

FIGN

571

Q5HY92
KLFRNLTPRCFVTTN

DNAJC11

226

Q9NVH1
TALIFRDSFCRPNLV

OR10X1

176

Q8NGY0
VCRPARTLDTIQLAF

LPCAT1

411

Q8NF37
ENRASCSFFLPRITI

IL31RA

76

Q8NI17
QLPRVCTFRFPSTNI

FOXK2

136

Q01167
VICFLPSVVVRIRIF

HCAR2

241

Q8TDS4
CAQIFREARRTVPSI

ATAD2B

816

Q9ULI0
LNICVFPREVTNFLR

CYP3A4

236

P08684
SAVAALPLCVFFRVV

FFAR4

166

Q5NUL3
VIATFSLPFCGRNRI

OR14L1P

161

Q8NHC6
RQPLYRFITTICAII

ERGIC1

246

Q969X5
FPVRAALVRQSCSQL

FAM151B

201

Q6UXP7
TCIVPEAFLLFSRRA

LRP6

626

O75581
VFNTFLRCLGIPARI

F13A1

321

P00488
CVREFTQFLTPLRNI

PTPDC1

236

A2A3K4
SAVQTVFVVQLPFCR

OR13C5

156

Q8NGS8
VVIFITAVVRCRQAP

PCDH11X

826

Q9BZA7
AAPDTIICSFRRVFL

GRM8

641

O00222
LCAISVDRFVAVAVP

DRD4

126

P21917
SQFLQTCTGFRLRPV

PAH

231

P00439
FFLLVSPRRCGAVET

IRGC

136

Q6NXR0
FVQVVLTVQLPFCGR

OR2B11

161

Q5JQS5
RFVRFCDAFNIPLIT

PCCB

376

P05166
QAQSRCVFLLTLFPR

ATR

631

Q13535
VLVIECNLRASRSFP

CPS1

1251

P31327
LPFQFTRTATVCGRE

CDC42EP2

81

O14613
VARGTFPVLVRTSAC

CDKN1C

16

P49918
FPVLVRTSACRSLFG

CDKN1C

21

P49918
RAVTVAFCTLPTREV

CPTP

156

Q5TA50
CLRFFSITGRAVIAP

CALHM4

101

Q5JW98
VSQRCEVRPEVLFLT

APCDD1

296

Q8J025
RNFCRFVTAINNTPR

DENND5A

1196

Q6IQ26
VARVLTPDAFVCRTI

KLKB1

216

P03952
AATVFFCLGQTTRPR

CACNA1H

76

O95180
VFRAITIAGRINCPV

CRMP1

236

Q14194
VAITQVTSVFRLPFC

OR10J1

166

P30954
FALTPQQVREICISR

PIAS2

181

O75928
PLCRTIISRVFFQTE

RNF180

471

Q86T96
SLVSVPLQCFQLSRV

SLC8B1

541

Q6J4K2
RFSIGQRVFIPCVVV

DSCAM

606

O60469
FVTCVRQPEFRAVLG

VARS1

191

P26640
PCIFNLLVNFVSSRI

ERVW-1

466

Q9UQF0
PFSARVLVLCVFNSI

SOAT1

356

P35610
AVCAFRPQDIRTVLN

SEMA4F

341

O95754
IIPALQSRCTRFRFG

RFC5

161

P40937
FRIECPRRLSQTFNF

SAMD3

476

Q8N6K7
RRSFIAAPCQIITNT

SGO1

36

Q5FBB7
FIIFVRCNPVQFAGI

SLCO6A1

471

Q86UG4
PIAAVFVLAIFCKRV

SLC5A4

466

Q9NY91
RVIVQRILPCLTSEF

SCYL2

366

Q6P3W7
QLPVVVFTFSRGRCD

SKIV2L

566

Q15477
VSPQDTVQRCREIFF

PMM1

241

Q92871
PDRFVVCVSQLAFSR

SLX4IP

111

Q5VYV7
PASRCVLVFEQVRFL

SOAT2

226

O75908
VTDRCIRNIFTVPEL

C12orf40

341

Q86WS4
TTLRNTTPNFVRCII

MYH11

666

P35749
SQSIARFFCRRVESP

RECQL5

761

O94762
TFRTPAVSVVFPLCQ

RNF212

276

Q495C1
RVRAVSASALRFCNP

SPTBN2

586

O15020
LRLTDPQRFFLTCVS

TIE1

31

P35590
QRTLVCPICRYVTFL

RNF222

56

A6NCQ9
FVPRICSLVIDSRVN

SYCP2

151

Q9BX26
VRLVPSSCRGLQFVV

UBE3D

61

Q7Z6J8
LTQPQVVARALCLVF

nan

21

A8MWL6
LTQPQVVARAVCLVF

SYNGR2

21

O43760
IVEYIRRFVVSCTPS

USP20

516

Q9Y2K6
RISQERLCRASPFAV

VWA5B2

1081

Q8N398
RFTEQPITDFCSVIR

ZNF277

106

Q9NRM2
RIQPAVFAFPCATLI

TMEM130

336

Q8N3G9
VVCTIAIVIGRFPRA

SLC26A7

461

Q8TE54
TIAGLNIAPCVRFTR

MYRIP

766

Q8NFW9