Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentstereocilium

STRC MYO15A STRCP1

2.47e-0469373GO:0032420
GeneOntologyCellularComponentkinocilium

STRC STRCP1

2.74e-0414372GO:0060091
GeneOntologyCellularComponent9+2 non-motile cilium

STRC STRCP1

2.74e-0414372GO:0097732
GeneOntologyCellularComponentstereocilium bundle

STRC MYO15A STRCP1

3.68e-0479373GO:0032421
GeneOntologyCellularComponentstereocilium tip

STRC STRCP1

6.89e-0422372GO:0032426
MousePhenoabnormal cochlear hair cell physiology

STRC MYO15A STRCP1

6.05e-0540273MP:0004432
MousePhenoabsent distortion product otoacoustic emissions

STRC MYO15A STRCP1

6.52e-0541273MP:0004737
MousePhenoabnormal hair cell physiology

STRC MYO15A STRCP1

1.12e-0449273MP:0003879
DomainEGF_Ca-bd_CS

C1S LTBP3 LTBP4 VCAN CRB2

9.77e-0797355IPR018097
DomainEGF_CA

C1S LTBP3 LTBP4 VCAN CRB2

1.08e-0699355PS01187
DomainASX_HYDROXYL

C1S LTBP3 LTBP4 VCAN CRB2

1.14e-06100355PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

C1S LTBP3 LTBP4 VCAN CRB2

1.52e-06106355IPR000152
DomainEGF_CA

C1S LTBP3 LTBP4 VCAN CRB2

3.04e-06122355SM00179
DomainEGF-like_Ca-bd_dom

C1S LTBP3 LTBP4 VCAN CRB2

3.29e-06124355IPR001881
DomainEGF_3

C1S LTBP3 MALRD1 LTBP4 VCAN CRB2

4.45e-06235356PS50026
DomainEGF-like_dom

C1S LTBP3 MALRD1 LTBP4 VCAN CRB2

6.21e-06249356IPR000742
DomainEGF_1

C1S LTBP3 MALRD1 LTBP4 VCAN CRB2

7.11e-06255356PS00022
DomainEGF-like_CS

C1S LTBP3 MALRD1 LTBP4 VCAN CRB2

8.12e-06261356IPR013032
DomainEGF_2

C1S LTBP3 MALRD1 LTBP4 VCAN CRB2

8.86e-06265356PS01186
DomainTB

LTBP3 LTBP4

7.12e-057352PF00683
DomainEGF

LTBP3 MALRD1 LTBP4 VCAN CRB2

7.21e-05235355SM00181
DomainEGF

C1S MALRD1 VCAN CRB2

8.79e-05126354PF00008
Domain-

LTBP3 LTBP4

9.49e-0583523.90.290.10
DomainTB

LTBP3 LTBP4

1.22e-049352PS51364
DomainTB_dom

LTBP3 LTBP4

1.22e-049352IPR017878
DomainEGF_CA

C1S LTBP3 LTBP4

5.55e-0486353PF07645
DomainhEGF

LTBP3 CRB2

1.25e-0328352PF12661
DomainGrowth_fac_rcpt_

ERBB3 LTBP3 LTBP4

3.08e-03156353IPR009030
DomainSushi

C1S VCAN

4.27e-0352352PF00084
DomainCCP

C1S VCAN

4.59e-0354352SM00032
DomainSUSHI

C1S VCAN

4.93e-0356352PS50923
DomainSushi_SCR_CCP_dom

C1S VCAN

5.10e-0357352IPR000436
DomainConA-like_dom

MALRD1 TRIM62 CRB2

7.90e-03219353IPR013320
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

GDF5 LTBP3 LTBP4

2.99e-0532273MM14854
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

GDF5 LTBP3 LTBP4

4.66e-0537273M27134
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

GDF5 LTBP3 LTBP4

5.47e-0539273MM14601
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

GDF5 LTBP3 LTBP4

7.88e-0544273M26969
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

LTBP3 LTBP4

9.82e-058272M47850
Pubmed

Versican G1 and G3 domains are upregulated and latent transforming growth factor-β binding protein-4 is downregulated in breast cancer stroma.

LTBP4 VCAN

1.10e-06237221505857
Pubmed

Control of lung development by latent TGF-β binding proteins.

LTBP3 LTBP4

1.10e-06237220945348
Pubmed

Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.

STRC STRCP1

1.10e-06237234910522
Pubmed

Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.

STRC STRCP1

1.10e-06237211687802
Pubmed

Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.

STRC STRCP1

3.30e-06337230801007
Pubmed

Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.

STRC STRCP1

6.60e-06437218849963
Pubmed

Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.

LTBP3 LTBP4

6.60e-06437215611103
Pubmed

The latent transforming growth factor beta binding protein (LTBP) family.

LTBP3 LTBP4

6.60e-06437211104663
Pubmed

Sequential deposition of latent TGF-beta binding proteins (LTBPs) during formation of the extracellular matrix in human lung fibroblasts.

LTBP3 LTBP4

6.60e-06437216157329
Pubmed

Assessment of the association between genetic polymorphisms in transforming growth factor beta, and its binding protein (LTBP), and the presence, and expansion, of Abdominal Aortic Aneurysm.

LTBP3 LTBP4

1.10e-05537219897194
Pubmed

An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.

STRC STRCP1

1.10e-05537224920589
Pubmed

Tubulin polymerization-promoting protein family member 3, Tppp3, is a specific marker of the differentiating tendon sheath and synovial joints.

GDF5 TNMD

1.10e-05537219235716
Pubmed

Digits in a dish: An in vitro system to assess the molecular genetics of hand/foot development at single-cell resolution.

GDF5 TNMD

1.65e-05637236994104
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

LTBP3 SARS2 TTC3 SZT2 FAAP100 LTBP4 TMEM158 ARHGAP26

1.72e-05110537835748872
Pubmed

Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta.

LTBP3 LTBP4

2.30e-05737210930463
Pubmed

Functional consequence of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa.

LTBP3 LTBP4

3.07e-05837227339457
Pubmed

Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.

STRC STRCP1

3.07e-05837221165971
Pubmed

Loss of the cytoskeletal protein Pdlim7 predisposes mice to heart defects and hemostatic dysfunction.

ERBB3 VCAN

3.95e-05937224278323
Pubmed

Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.

STRC STRCP1

6.02e-051137231776257
Pubmed

Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.

STRC STRCP1

6.02e-051137231448880
Pubmed

Common cellular origin and diverging developmental programs for different sesamoid bones.

GDF5 TNMD

8.53e-051337230745426
Pubmed

Long form of latent TGF-beta binding protein 1 (Ltbp1L) is essential for cardiac outflow tract septation and remodeling.

LTBP3 LTBP4

1.15e-041537217804598
Pubmed

Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage.

GDF5 TNMD

1.15e-041537220206616
Pubmed

Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation.

ERBB3 VCAN

1.48e-041737222183742
Pubmed

Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.

STRC STRCP1

1.48e-041737220856818
Pubmed

Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry.

GDF5 HK3

1.86e-041937212543931
Pubmed

A single cell transcriptional atlas of early synovial joint development.

GDF5 TNMD

2.07e-042037232580935
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

JPH1 IPO5 C1S ERBB3 LTBP3 SARS2 TTC3

3.60e-04128537735914814
Pubmed

Developmental gene expression profiling along the tonotopic axis of the mouse cochlea.

MYO15A TNMD

4.09e-042837222808246
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

LTBP3 LTBP4 VCAN

5.07e-0414637327068509
Pubmed

β-Catenin regulates endocardial cushion growth by suppressing p21.

ERBB3 VCAN

6.41e-043537237385754
Pubmed

Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.

LTBP3 LTBP4

6.78e-043637220587546
Pubmed

A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis.

STRC STRCP1

7.56e-043837238346162
Pubmed

A genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 network.

JPH1 AGBL2

8.37e-044037220308539
Cytoband15q15.3

STRC STRCP1

1.87e-042537215q15.3
GeneFamilyLatent transforming growth factor beta binding proteins

LTBP3 LTBP4

7.70e-064212628
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

C1S VCAN

1.97e-03572121179
GeneFamilyActins|Deafness associated genes

STRC MYO15A

7.52e-031132121152
ToppCellfacs-Bladder-nan-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP4 LITAF TMEM158 VCAN

5.52e-07194375f4c9fc53ae31d58096906d9305b0b4082512a7e9
ToppCellfacs-Bladder-nan-18m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP4 LITAF TMEM158 VCAN

5.66e-071953753e4f9ecfaa756386d816a26313b7229ec092d4e6
ToppCellfacs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 C1S LTBP3 LTBP4

1.10e-0516737478909f685ccd1321064eb0887caf9263e0e54879
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

JPH1 ERBB3 MALRD1 RIC3

1.44e-05179374cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

C1S LTBP4 TMEM158 VCAN

1.48e-05180374ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNMD LTBP4 TMEM158 VCAN

1.82e-05190374c01a8bfb9fbc0e6f37d7e9be25512eda63acabbc
ToppCell15-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

C1S LTBP4 CRB2 RIC3

1.82e-05190374b47472dc9fe6ed99c2365203a3d8a59879e74a70
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C1S LTBP4 TMEM158 VCAN

1.86e-0519137475d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C1S LTBP4 TMEM158 VCAN

1.86e-051913749f478f36a0b895e607e3bb77fa0f9f03cc0f33fc
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1S TNMD LTBP4 VCAN

1.86e-051913744e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C1S LTBP4 TMEM158 VCAN

1.86e-051913744b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1S LTBP4 LITAF VCAN

1.86e-0519137489d03c4133dda852a3713c0902a7d67941cf5b21
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1S LTBP3 LTBP4 VCAN

1.90e-0519237432acd89617934016cd135d2cc797e8e79ae1b37f
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP3 LTBP4 VCAN

1.90e-05192374a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1S LTBP4 TMEM158 VCAN

1.90e-051923740e7e55505bd5454d7cf952a63fdcb46ec76f1973
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP3 LTBP4 VCAN

1.90e-05192374eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1S LTBP4 TMEM158 VCAN

1.94e-05193374025836c5c5a711e477c326559e618e47cae42d11
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP3 LTBP4 TMEM158

1.94e-05193374858a186804b36d45957238d3d3eed2768b961641
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP3 LTBP4 VCAN

1.94e-05193374d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP3 LTBP4 TMEM158

1.94e-051933747865e7ec0a288249540d4cba94ae01c93e1b617c
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C1S LTBP4 TMEM158 VCAN

1.94e-05193374051f61156b0e2e95292b2d8377faf3190b50f264
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP4 LITAF VCAN

1.98e-05194374ee6b5fb4e993a4c0dc556091b8fefd56bdc70d8f
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP4 LITAF VCAN

2.02e-05195374841fde528ecb293e07b5e00e499d1e9f0b0dce14
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP3 LTBP4 VCAN

2.02e-0519537469a29d03e664b72f32d41876510c62345c3aed31
ToppCellfacs-GAT-Fat-3m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP3 LTBP4 VCAN

2.02e-051953741cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP3 LTBP4 VCAN

2.02e-051953749cef6f18664518060af7c192310dddce6d70345a
ToppCelldroplet-Bladder-nan-3m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP4 TMEM158 VCAN

2.06e-05196374f47e551ba484687ba6ce8c29a085106131364042
ToppCell15-Distal-Mesenchymal|Distal / Age, Tissue, Lineage and Cell class

C1S LTBP4 LITAF VCAN

2.06e-05196374b8d95b5f4780e73d16dcc528e70a5496f0314373
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1S LTBP4 TMEM158 VCAN

2.10e-05197374398a66c06df63567b176ab2cc85e27837e94d0d9
ToppCell11.5-Distal-Mesenchymal|Distal / Age, Tissue, Lineage and Cell class

C1S LTBP4 LITAF VCAN

2.14e-051983745c606d881f151404287d9b43c9490e9bb486ef54
ToppCellfacs-Trachea-3m-Mesenchymal|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1S LTBP3 LTBP4 VCAN

2.14e-05198374e85ae846e293687fd193f4d565525d8d3bd1faea
ToppCellfacs-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP3 LTBP4 VCAN

2.14e-051983740dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

C1S LTBP4 VCAN CRB2

2.19e-05199374c972d3036151403f26fa9d6271520639c281ab84
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1S LTBP4 LITAF VCAN

2.19e-0519937484545ced0c792bc77980a50d65e484eab648d47e
ToppCell18-Distal-Mesenchymal|Distal / Age, Tissue, Lineage and Cell class

C1S LTBP4 LITAF VCAN

2.19e-05199374d65150d2e24c40aa82712e7f034f6772102bd293
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

C1S LTBP4 VCAN CRB2

2.19e-05199374b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCellwk_08-11-Mesenchymal-Fibroblast-intermediate_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

C1S LTBP4 LITAF VCAN

2.19e-05199374f9e3fb974ba8fe1b6d99892577549ef143df9e08
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

C1S LTBP4 LITAF VCAN

2.19e-05199374f19c683f38bca3bfee40396f27423441051dec67
ToppCellfacs-Trachea-nan-3m-Mesenchymal|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP3 LTBP4 VCAN

2.19e-0519937467f78c070c56e44fba36542041bf7fa1c291807c
ToppCellfacs-Trachea-nan-3m-Mesenchymal-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP3 LTBP4 VCAN

2.19e-051993741ae244b563f85c1ee8d22698f478c842a4d9c7f5
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1S LTBP4 LITAF VCAN

2.19e-05199374bdedcc7c8f3be0996200c882dda82fb2658655c0
ToppCellwk_08-11-Mesenchymal-Fibroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

C1S LTBP4 LITAF VCAN

2.23e-05200374482dfbbd8958b64c31568dccbffe3cc9589f876b
ToppCellwk_20-22-Mesenchymal-Fibroblast-Alveolar_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

C1S LTBP4 LITAF VCAN

2.23e-052003740ed49c2177b58269ff7653db6be7d68633a5d34a
ToppCell18-Airway-Mesenchymal-Mesenchyme_SERPINF1-high|Airway / Age, Tissue, Lineage and Cell class

C1S TTC3 LTBP4 VCAN

2.23e-0520037414ae55660f7412518dcb5cb982f6fe9f23553cfb
ToppCell15-Airway-Mesenchymal|Airway / Age, Tissue, Lineage and Cell class

C1S TTC3 LTBP4 VCAN

2.23e-0520037413c4835b98e1bb91c2d04e08cdeaed8eba30b1d9
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

C1S LTBP4 VCAN

1.67e-0412937313cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCellLPS-antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STRC AGBL2 TRIM62

2.60e-041503739cb3332924bd67c966873343c14445e30d3f384f
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM53B AGBL2 LITAF

2.60e-04150373afd651c654e715414eff64cf3a37378d057a56a2
ToppCellRSV-Healthy-6|RSV / Virus stimulation, Condition and Cluster

TCF20 AGBL2 ZNF598

3.37e-04164373ab312b8c2f828ea7331f2a340c4df81587a23b5c
ToppCellRSV-Healthy-6|Healthy / Virus stimulation, Condition and Cluster

TCF20 AGBL2 ZNF598

3.37e-041643731b9c5a6dc4e09b90f92e98b81a5ee620f8479cc7
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intermediate_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

HK3 TMEM158 VCAN

3.43e-04165373c3fa9225d2f9c9e821d4fbd2315fcc98ce1f1c55
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

MALRD1 LTBP4 VCAN

3.49e-0416637365dafed953b01a9830b54309af75c7a561e88336
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MUC19 SARS2 ZNF598

3.49e-04166373c11dcf9705b85ac3da6ae86358f5ffd64ae8327e
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1S LTBP4 VCAN

3.68e-04169373c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C1S LTBP4 VCAN

3.68e-04169373335619507857383c3b0b507cdf05d786ed59e585
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LTBP4 LITAF VCAN

3.75e-04170373b5b47fe42617a4c2ebb49c8ed55db3926213a75a
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

JPH1 MALRD1 RIC3

3.94e-04173373b799c06a6a5754668e789f70c0c8bc1508568575
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C1S LTBP4 CRB2

4.01e-04174373a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERBB3 STRC SEMA4G

4.08e-041753736759d200a133034756de9cdf2d5daceca927aac9
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S TMEM158 VCAN

4.15e-04176373ef0ff02897104e938c8a632357d8f1a6f014e68a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S TMEM158 VCAN

4.15e-04176373da0983929fa682a68e536c298a2d7add188b7563
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

C1S LTBP4 VCAN

4.22e-041773739ec7f1e64312d26d434b3312b58386715dbad644
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

C1S LTBP4 VCAN

4.22e-04177373016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SARS2 HK3 SZT2

4.36e-041793739dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCell-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

C1S TNMD LTBP4

4.36e-0417937310fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1S LTBP4 VCAN

4.43e-04180373f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1S LTBP3 VCAN

4.43e-0418037339ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCellLPS-IL1RA-Myeloid-Neutrophils-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LITAF ARHGAP26 VCAN

4.43e-04180373c0c07937839652e01df10cc1e70aa005800ea6f6
ToppCellLPS-IL1RA-Myeloid-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LITAF ARHGAP26 VCAN

4.43e-04180373079c199425dd3c220f03c6dca1823946f07580a1
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

C1S LTBP4 VCAN

4.43e-041803739adebde5f4ca6dcb90e9113622862e14298465ac
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1S LTBP4 VCAN

4.50e-04181373e1ae9ada60ec89e7a7cde9c231c1a099ed2ffecc
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

C1S LTBP4 VCAN

4.50e-04181373c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

C1S LTBP4 VCAN

4.50e-04181373c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

C1S LTBP4 VCAN

4.57e-04182373e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCellLPS-IL1RA+antiTNF-Myeloid-Neutrophils|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LITAF ARHGAP26 VCAN

4.57e-04182373243c783675df495ea4112dbf710712c44ea6b4f1
ToppCellLPS_only-Myeloid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LITAF ARHGAP26 VCAN

4.57e-04182373666ac86ee5f6fa9241ae8d80340743707e54b278
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1S LTBP4 VCAN

4.57e-041823733dfa9187e9d2bab1d199079d29209c4648220ada
ToppCellLPS-IL1RA+antiTNF-Myeloid-Neutrophils-Neutrophils|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LITAF ARHGAP26 VCAN

4.57e-0418237318790a394dc32b3cef99cdbf826392c520e38b4a
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFAP61 CRB2 RIC3

4.65e-04183373c5caac6ed6c8d67f5c336281d9fd903976509445
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGBL2 LTBP4 TMEM158

4.65e-041833736f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

FAM53B LITAF ARHGAP26

4.65e-04183373f593a89b0aa8fffdfa403769916facfd30358521
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFAP61 CRB2 RIC3

4.65e-041833739d5a363fbe6f0a1668c9d584df65ee1c283349c7
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDF5 C1S CRB2

4.65e-04183373f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

C1S LTBP4 TMEM158

4.72e-0418437301257e5c12e38b849fd3d9496c43ded666249ba5
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGBL2 LTBP4 TMEM158

4.72e-04184373f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGBL2 LTBP4 TMEM158

4.72e-041843738bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

C1S LTBP3 LTBP4

4.79e-04185373e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1S LTBP4 VCAN

4.79e-04185373d5f5866924648a3c14e2596218fd548a31777aa3
ToppCellLPS-IL1RA-Myeloid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HK3 LITAF VCAN

4.79e-041853739b5fd87ea9d05e051ff1251578ecfbe5e8652853
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S TNMD LTBP4

4.79e-04185373785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S TNMD LTBP4

4.79e-0418537397a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDF5 LTBP3 CRB2

4.79e-04185373872720275789d249c9859de825a923803d458875
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

C1S LTBP4 TMEM158

4.87e-04186373c0a036096c2cb23305605b8aaf18869d6e0fb512
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP3 VCAN

4.87e-0418637335c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP3 VCAN

4.87e-04186373d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1S LTBP4 VCAN

4.87e-04186373f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCelldroplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP4 TMEM158 RIC3

4.87e-041863735d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S TNMD LTBP4

4.87e-0418637394d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCellControl-Fibroblasts-Pathological_FB|Control / group, cell type (main and fine annotations)

C1S TMEM158 VCAN

4.95e-04187373b7280b8baa0fba9c2b4bff660c240ed96f6ff9b7
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1S LTBP4 VCAN

4.95e-041873734e553721fa5598cb211f44e3226280b7e6885484
DrugBufexamac [2438-72-4]; Up 200; 18uM; MCF7; HT_HG-U133A

IPO5 TMEM158 SEMA4G ARHGAP26 VCAN

1.43e-051983655515_UP
DrugOxantel pamoate [68813-55-8]; Down 200; 6.6uM; PC3; HT_HG-U133A

FAM53B FAAP100 ARHGAP26 VCAN TRIM62

1.43e-051983656738_DN
Diseasebrain volume measurement

GDF5 FAM53B ERBB3 AGBL2 SZT2 LTBP4 VCAN CRB2

4.80e-07595368EFO_0006930
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

1.45e-062362DOID:0110471 (implicated_via_orthology)
Diseaseneuroimaging measurement, brain volume measurement

JPH1 GDF5 FAM53B VCAN CRB2

2.43e-05286365EFO_0004346, EFO_0006930
Diseasebrain connectivity measurement

GDF5 FAM53B ERBB3 TMEM158 VCAN

1.19e-04400365EFO_0005210
DiseaseOsteoarthritis of hip

GDF5 LTBP3

2.71e-0420362C0029410
Diseasesensorineural hearing loss (is_implicated_in)

STRC MYO15A

7.46e-0433362DOID:10003 (is_implicated_in)
Diseasejoint hypermobility measurement

GDF5 VCAN

7.46e-0433362EFO_0007905
Diseasehippocampus molecular layer volume

FAM53B VCAN

8.40e-0435362EFO_0009397
DiseaseDevelopmental delay (disorder)

TCF20 SZT2

9.38e-0437362C0424605
Diseasecolorectal cancer, endometrial neoplasm

MALRD1 LITAF

1.21e-0342362EFO_0004230, MONDO_0005575
DiseaseCharcot-Marie-Tooth disease

JPH1 LITAF

1.21e-0342362cv:C0007959

Protein segments in the cluster

PeptideGeneStartEntry
REFAHEAECFSCHPE

ERBB3

541

P21860
VPCNHFTLNEEEDCF

CFAP61

806

Q8NHU2
GDQCELDFDECHSNP

VCAN

3121

P13611
DLVEDSCLGFCFEVH

ATXN7L3

26

Q14CW9
PCNAQELEECDIFFE

NUDCD1

401

Q96RS6
FCVDALQDVDHYCPN

LITAF

136

Q99732
PLEYEAFHCEGLCEF

GDF5

421

P43026
LDDQCCFPQATDHTF

MYO15A

1661

Q9UKN7
LHDGACRDLFDAFAC

CRB2

1066

Q5IJ48
DVDCDFCPVEDHVDA

JPH1

261

Q9HDC5
PSFDDHLACQEDLSC

FAM53B

361

Q14153
DPSAYHDACIEEACA

MUC19

1486

Q7Z5P9
CFHEDEDPAVLAENA

RIC3

306

Q7Z5B4
CIFDDVIEHCSPASF

IPO5

886

O00410
FLPDEDVHCDCLVAF

FAAP100

301

Q0VG06
DFAAHCLSEFLDAQP

HK3

141

P52790
SHLCADFAACVPQED

PASD1

151

Q8IV76
CDGVPDCHFNEDELI

MALRD1

1966

Q5VYJ5
DINECTDFVDVPCSH

C1S

131

P09871
YHVCDTLLDFCDPDQ

AGBL2

656

Q5U5Z8
RSHCEDIDECDFPAA

LTBP3

821

Q9NS15
DCALCPAQDSDDFEA

LTBP4

1386

Q8N2S1
ERFCACPEEAAHALE

SARS2

61

Q9NP81
DDFDVSLLVCHCAAP

SZT2

3161

Q5T011
PECDQSEEFHKLCFA

SLFN14

881

P0C7P3
LEFSDCCLDSPHFRE

ARHGAP26

6

Q9UNA1
LSFCTDLEIPHFFCE

OR7A17

166

O14581
ACHDQFPDEFLDAIC

STRC

411

Q7RTU9
PENCEDCHILNAEAF

TNMD

6

Q9H2S6
HAFQPLCAAIDAEAF

SEMA4G

136

Q9NTN9
HFCCLDFSLEELQGE

TMEM158

196

Q8WZ71
CLDNECADFRLHEAP

SOGA1

446

O94964
LLEDCPHVDDCVFAA

TTC3

16

P53804
PCAIDADCLLHEENF

TCF20

1911

Q9UGU0
HPLCKFCDERYLDND

ZNF598

186

Q86UK7
ACHDQFPDEFLDAIC

STRCP1

411

A6NGW2
DRALLCFFCDEPALH

TRIM62

106

Q9BVG3
CFFCDEPALHEQHQV

TRIM62

111

Q9BVG3
ECLNESDEHGFDNCL

TXNL1

136

O43396