Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

NCOR2 AP2A2 RB1 TLE4 BCORL1 ATF7IP2 SMARCA4 IRAK2 SORBS1 DOK2 CNTLN STX7 NCK2 NPAT

4.18e-0511607014GO:0030674
GeneOntologyMolecularFunctionsmall GTPase binding

PLEKHG1 RANBP10 GAPVD1 MYO9B ARHGEF7 EXPH5 TSC2

1.31e-04321707GO:0031267
GeneOntologyMolecularFunctiontranscription corepressor activity

NCOR2 RB1 TLE4 BCORL1 SMARCA4 NPAT

1.51e-04229706GO:0003714
GeneOntologyMolecularFunctionmolecular adaptor activity

NCOR2 AP2A2 RB1 TLE4 BCORL1 ATF7IP2 SMARCA4 IRAK2 SORBS1 DOK2 CNTLN STX7 NCK2 NPAT

2.20e-0413567014GO:0060090
GeneOntologyMolecularFunctionGTPase binding

PLEKHG1 RANBP10 GAPVD1 MYO9B ARHGEF7 EXPH5 TSC2

2.64e-04360707GO:0051020
GeneOntologyMolecularFunctionkinase binding

CYLD AP2A2 RB1 ARHGEF7 APC TNS2 SORBS1 DOK2 CNTLN CIT NCK2

5.19e-049697011GO:0019900
GeneOntologyMolecularFunctionprotein kinase binding

CYLD AP2A2 ARHGEF7 APC TNS2 SORBS1 DOK2 CNTLN CIT NCK2

8.90e-048737010GO:0019901
GeneOntologyMolecularFunctionsignaling receptor complex adaptor activity

SORBS1 DOK2 NCK2

9.00e-0454703GO:0030159
GeneOntologyMolecularFunctionsignaling adaptor activity

IRAK2 SORBS1 DOK2 NCK2

1.10e-03129704GO:0035591
GeneOntologyMolecularFunctionenzyme regulator activity

PPP4R1 PLEKHG1 RANBP10 GAPVD1 DENND4A SERPINI1 MYO9B ARHGEF7 APC FNIP1 TSC2 CIT DCP1A

1.16e-0314187013GO:0030234
GeneOntologyMolecularFunctiontranscription factor binding

NCOR2 GRHL1 RB1 TLE4 ZNF516 PITX2 SMARCA4 CIT DCP1A

1.22e-03753709GO:0008134
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

PLEKHG1 RANBP10 GAPVD1 DENND4A ARHGEF7

1.30e-03231705GO:0005085
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

PLEKHG1 RANBP10 GAPVD1 DENND4A MYO9B ARHGEF7 TSC2

1.97e-03507707GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

PLEKHG1 RANBP10 GAPVD1 DENND4A MYO9B ARHGEF7 TSC2

1.97e-03507707GO:0030695
GeneOntologyBiologicalProcessnegative regulation of intracellular signal transduction

CYLD NCOR2 ASH1L APC SMARCA4 FNIP1 TSC2 MINAR1 DOK2 CMYA5 CIT NCK2

1.16e-057956912GO:1902532
Domaincwf21

U2SURP SRRM2

1.38e-052702PF08312
DomainmRNA_splic_Cwf21_dom

U2SURP SRRM2

1.38e-052702IPR013170
DomainZF_DAG_PE_1

MYO9B TNS2 CIT

1.78e-0364703PS00479
DomainZF_DAG_PE_2

MYO9B TNS2 CIT

1.78e-0364703PS50081
DomainC1

MYO9B TNS2 CIT

1.86e-0365703SM00109
DomainPE/DAG-bd

MYO9B TNS2 CIT

1.95e-0366703IPR002219
Domain-

PLEKHG1 ARHGEF7 TNS2 DOK2 CIT DCP1A

3.44e-033917062.30.29.30
DomainLisH

RANBP10 NPAT

4.91e-0328702SM00667
DomainLisH

RANBP10 NPAT

4.91e-0328702IPR006594
DomainLISH

RANBP10 NPAT

4.91e-0328702PS50896
DomainPH_dom-like

PLEKHG1 ARHGEF7 TNS2 DOK2 CIT DCP1A

5.21e-03426706IPR011993
DomainSPRY

RANBP10 CMYA5 RNF39

5.30e-0394703PF00622
DomainSPRY_dom

RANBP10 CMYA5 RNF39

5.30e-0394703IPR003877
DomainB30.2/SPRY

RANBP10 CMYA5 RNF39

5.46e-0395703IPR001870
DomainB302_SPRY

RANBP10 CMYA5 RNF39

5.46e-0395703PS50188
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CYLD PPP4R1 NCOR2 RB1 LMO7 MYO9B ZNF516 BCORL1 APC SORBS1 ZNF318 CNTLN NCK2

1.92e-10588711338580884
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CYLD RANBP10 NCOR2 AP2A2 ATXN2 ARHGEF7 ZNF516 APC SMARCA4 TSC2 SORBS1 ZNF318 ARMCX4 CIT

7.88e-09963711428671696
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NCOR2 GAPVD1 TLE4 ZNF516 BCORL1 ATF7IP2 APC ZNF318 DCP1A NPAT

1.36e-08418711034709266
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CYLD PLEKHG1 GAPVD1 DENND4A LMO7 EXPH5 APC FNIP1 TSC2 SORBS1 PPIP5K2 SRRM2 DCP1A

1.85e-08861711336931259
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NCOR2 GAPVD1 LMO7 TLE4 ZC3H13 ZNF516 ZBTB40 SMARCA4 ZNF318 SRRM2 CLASRP DCP1A

5.22e-08774711215302935
Pubmed

Combinatorial CRISPR screen identifies fitness effects of gene paralogues.

AP2A2 RB1 SMARCA4 FNIP1 SRRM2 NCK2 DCP1A

1.11e-0718671733637726
Pubmed

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.

GAPVD1 DENND4A LMO7 ZC3H13 APC TSC2 DCP1A

1.29e-0719071715161933
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

CYLD PLEKHG1 GAPVD1 DENND4A AP2A2 LMO7 APC TSC2 SORBS1

3.19e-0744671924255178
Pubmed

A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer.

RB1 APC SMARCA4

4.53e-07871325069779
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

GAPVD1 DENND4A LMO7 ARHGEF7 TSC2 SRRM2 DCP1A

9.35e-0725571715324660
Pubmed

Human transcription factor protein interaction networks.

CYLD NCOR2 RB1 ATXN2 TLE4 ZNF516 BCORL1 ZBTB40 SMARCA4 ZNF318 SRRM2 CIT DCP1A NPAT

9.83e-071429711435140242
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

ZBTB37 NCOR2 GAPVD1 RB1 MYO9B TLE4 PITX2 ZBTB40 SMARCA4 LARP7 DCP1A

1.27e-06857711125609649
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ZNF7 CYLD PPP4R1 LMO7 ASH1L APC SMARCA4 TSC2 SORBS1 ARMCX4 CMYA5 CIT MTUS2

1.78e-061285711335914814
Pubmed

RB localizes to DNA double-strand breaks and promotes DNA end resection and homologous recombination through the recruitment of BRG1.

RB1 SMARCA4

4.11e-06271227940962
Pubmed

Inactivation of conditional Rb by Villin-Cre leads to aggressive tumors outside the gastrointestinal tract.

RB1 APC

4.11e-06271216585182
Pubmed

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest.

RB1 SMARCA4

4.11e-0627127923370
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

CYLD GAPVD1 DENND4A APC FNIP1 DCP1A

4.53e-0620971636779422
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

ZC3H14 NCOR2 GAPVD1 AP2A2 LMO7 MYO9B U2SURP APC SRRM2 CIT LARP7 DCP1A

7.77e-061247711227684187
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

GAPVD1 LMO7 U2SURP SMARCA4 SORBS1 ZNF318 SRRM2 LARP7

9.05e-0650671830890647
Pubmed

BRG1 is required for formation of senescence-associated heterochromatin foci induced by oncogenic RAS or BRCA1 loss.

RB1 SMARCA4

1.23e-05371223438604
Pubmed

The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a.

RB1 SMARCA4

1.23e-05371219149898
Pubmed

Human X chromosome exome sequencing identifies BCORL1 as contributor to spermatogenesis.

BCORL1 ARMCX4

1.23e-05371232376790
Pubmed

Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon.

RB1 APC

1.23e-05371218832169
Pubmed

Characterization of mammary tumors from Brg1 heterozygous mice.

RB1 SMARCA4

1.23e-05371217637742
Pubmed

Expression of the proliferating cell nuclear antigen and protein products of tumour suppressor genes in the human foetal testis.

RB1 APC

1.23e-05371214871261
Pubmed

Brg1 chromatin remodeling factor is involved in cell growth arrest, apoptosis and senescence of rat mesenchymal stem cells.

RB1 SMARCA4

1.23e-05371217666433
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

ZC3H14 NCOR2 ATXN2 U2SURP ZNF516 BCORL1 ZBTB40 SMARCA4 ZNF318 SRRM2 CIT

1.39e-051103711134189442
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

CCSAP ZC3H14 ATXN2 MYO9B TLE4 ZC3H13 ZNF318 SRRM2 NCK2 DCP1A

1.75e-05922711027609421
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

NCOR2 GAPVD1 ATXN2 ZC3H13 ZNF318 SRRM2 DCP1A

1.76e-0539971735987950
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

USP17L7 GAPVD1 RB1 ZC3H13 SCN3A BCORL1 MUC19 TSC2 PCDH17

1.87e-0573671929676528
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CYLD PLEKHG1 TLE4 FNIP1 DISP2 SORBS1 SRRM2

1.99e-0540771712693553
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ZC3H14 NCOR2 ATXN2 ZC3H13 U2SURP BCORL1 SMARCA4 ZNF318 SRRM2 NPAT

2.34e-05954711036373674
Pubmed

BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines.

RB1 SMARCA4

2.46e-05471211085541
Pubmed

Brg1 is required to maintain colorectal cancer stem cells.

APC SMARCA4

2.46e-05471234415580
Pubmed

Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity.

RB1 APC

4.09e-05571219962666
Pubmed

Protein Phosphatase 1 binds strongly to the retinoblastoma protein but not to p107 or p130 in vitro and in vivo.

RB1 SMARCA4

4.09e-05571212434308
Pubmed

Prohibitin requires Brg-1 and Brm for the repression of E2F and cell growth.

RB1 SMARCA4

4.09e-05571212065415
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

ZC3H14 GAPVD1 LMO7 MYO9B U2SURP SMARCA4 ZNF318 STX7 SRRM2 CIT

4.25e-051024711024711643
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

NCOR2 ATXN2 ARHGEF7 APC MTUS2 LARP7 DCP1A

5.31e-0547571731040226
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

AP2A2 ZC3H13 SRRM2 LARP7 CLASRP

5.33e-0519771520811636
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

CYLD AP2A2 LMO7 ZC3H13

5.39e-0510071410048485
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ZC3H14 GAPVD1 ZC3H13 U2SURP SMARCA4 ZNF318 SRRM2 LARP7

5.56e-0565371822586326
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

PPP4R1 GAPVD1 DENND4A ATXN2 ARHGEF7 SMARCA4 TSC2 SORBS1 DOK2 CMYA5 SRRM2

5.58e-051284711117353931
Pubmed

USP1 deubiquitinates Akt to inhibit PI3K-Akt-FoxO signaling in muscle during prolonged starvation.

ARHGEF7 TSC2 CMYA5

6.03e-053771332133736
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC19 MUC16

6.13e-05671219110483
Pubmed

Lysine acetylation targets protein complexes and co-regulates major cellular functions.

DENND4A TSC2 SRRM2

6.53e-053871319608861
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

ATXN2 TLE4 U2SURP CNTLN SRRM2 LARP7 CLASRP DCP1A

6.65e-0567071822990118
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

CYLD GAPVD1 TLE4 ZC3H13 ASH1L ZBTB40 APC ZNF318 DCP1A NPAT

6.84e-051084711011544199
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

RB1 BCORL1 MUC19 SMARCA4 ZNF318 NPAT

6.90e-0533971630415952
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

ARHGEF7 APC SORBS1 STX7 SRRM2 CIT

7.84e-0534771617114649
Pubmed

Interaction network of human early embryonic transcription factors.

NCOR2 TLE4 ZNF516 BCORL1 PITX2 SMARCA4

8.35e-0535171638297188
Pubmed

Tumor suppressor gene mutations in mice.

RB1 APC

8.57e-0577128982467
Pubmed

A calcium-dependent switch in a CREST-BRG1 complex regulates activity-dependent gene expression.

RB1 SMARCA4

8.57e-05771219081374
Pubmed

Insights into cancer from transgenic mouse models.

RB1 APC

8.57e-05771210341706
Pubmed

The protein interaction landscape of the human CMGC kinase group.

RB1 TLE4 ZNF516 APC SRRM2 LARP7 NCK2 CLASRP

8.58e-0569571823602568
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CYLD AP2A2 LMO7 ZBTB40 MINAR1

9.97e-0522571512168954
Pubmed

Disruption of the Rb--Raf-1 interaction inhibits tumor growth and angiogenesis.

RB1 SMARCA4

1.14e-04871215485920
Pubmed

Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation.

ARHGEF7 NCK2

1.14e-04871217310244
Pubmed

Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3.

NCOR2 SMARCA4

1.47e-04971210944117
Pubmed

Independent SH2-binding sites mediate interaction of Dok-related protein with RasGTPase-activating protein and Nck.

DOK2 NCK2

1.47e-04971210428862
Pubmed

Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology to tensin.

TNS2 NCK2

1.47e-04971212470648
Pubmed

The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals.

SORBS1 NCK2

1.47e-04971211557983
Pubmed

KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.

ZC3H14 NCOR2 U2SURP SRRM2

1.49e-0413071435545047
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

RANBP10 U2SURP SORBS1 TSEN2

1.49e-0413071412421765
Pubmed

Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.

NCOR2 PCDH17 CLASRP DCP1A

1.63e-0413371415604093
Pubmed

Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

ARHGEF7 ZC3H13 DOK2 SRRM2

1.63e-0413371415144186
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NCOR2 RB1 ZNF516 BCORL1 APC SMARCA4

1.65e-0439871635016035
Pubmed

EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis.

APC MTUS2

1.83e-041071223001180
Pubmed

Cardiomyocyte DNA synthesis and binucleation during murine development.

RB1 TSC2

1.83e-04107128945939
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

GAPVD1 ATXN2 EXPH5 APC ZNF318

2.06e-0426371534702444
Pubmed

ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.

RB1 APC TSC2

2.20e-045771323788249
Pubmed

90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling.

TNS2 NCK2

2.23e-041171215117958
Pubmed

Targeting HIV transcription: the quest for a functional cure.

SMARCA4 LARP7

2.23e-041171225731772
Pubmed

Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood.

PITX2 APC

2.23e-041171219429790
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF7 ZBTB37 GRHL1 ZC3H13 ZNF516 PITX2 ASH1L ZNF318

2.40e-0480871820412781
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

ZC3H14 ATXN2 LMO7 SMARCA4 LARP7

2.49e-0427471534244482
Pubmed

PRDM paralogs antagonistically balance Wnt/β-catenin activity during craniofacial chondrocyte differentiation.

APC SMARCA4

2.68e-041271235132438
Pubmed

Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse.

APC TSC2

2.68e-041271219150975
Pubmed

Mouse models in tumor suppression.

RB1 APC

2.68e-04127129917000
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

ZC3H14 NCOR2 LMO7 ZC3H13 U2SURP BCORL1 SMARCA4 ZNF318 SRRM2 CLASRP

2.88e-041294711030804502
Pubmed

ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.

ZBTB37 TLE4 ZBTB40

2.97e-046371334351428
Pubmed

Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.

AP2A2 MYO9B U2SURP SRRM2

3.00e-0415671422952844
Pubmed

Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair.

APC SMARCA4

3.16e-041371229920279
Pubmed

Genotype phenotype correlations in Israeli colorectal cancer patients.

RB1 APC

3.16e-041371215523694
Pubmed

Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.

PPP4R1 NCOR2 ARHGEF7 SMARCA4

3.38e-0416171432572027
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

RANBP10 GAPVD1 DENND4A AP2A2 RB1 LMO7 TSC2 PPIP5K2 CLASRP DCP1A

3.39e-041321711027173435
Pubmed

Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry.

PITX2 SMARCA4

3.68e-041471217210915
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PLEKHG1 RANBP10 NCOR2 MYO9B ZNF516 DISP2 TSC2 CIT NCK2

4.06e-04110571935748872
Pubmed

Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.

RB1 APC SMARCA4

4.22e-047171328319113
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

ZC3H14 LMO7 ZC3H13 U2SURP SRRM2 LARP7

4.35e-0447771631300519
Pubmed

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells.

RB1 SORBS1 CLASRP

4.58e-047371322094256
Pubmed

A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1.

NCOR2 SMARCA4

4.84e-041671211013263
Pubmed

Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

RANBP10 ATXN2 U2SURP LARP7

5.36e-0418271432239614
Pubmed

Identification of RanBP 9/10 as interacting partners for protein kinase C (PKC) gamma/delta and the D1 dopamine receptor: regulation of PKC-mediated receptor phosphorylation.

RANBP10 SCN3A

5.48e-041771220395553
Pubmed

ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination.

RB1 CIT

5.48e-041771226581405
Pubmed

Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

NCOR2 SMARCA4

5.48e-041771219183483
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

PPP4R1 CCSAP ZC3H14 GAPVD1 AP2A2 PITX2 SMARCA4 TSC2

5.88e-0492571828986522
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC19 MUC16

6.16e-041871218834073
Pubmed

A Chimeric Egfr Protein Reporter Mouse Reveals Egfr Localization and Trafficking In Vivo.

PITX2 APC

6.16e-041871228494873
Pubmed

Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with Numb.

AP2A2 SRRM2

6.16e-041871223211419
InteractionYWHAH interactions

CYLD PLEKHG1 ZC3H14 GAPVD1 DENND4A LMO7 ARHGEF7 EXPH5 ZC3H13 APC FNIP1 TNS2 TSC2 SORBS1 PPIP5K2 SRRM2 DCP1A

1.94e-0711027117int:YWHAH
InteractionYWHAG interactions

CYLD PLEKHG1 GAPVD1 DENND4A LMO7 ARHGEF7 EXPH5 ZC3H13 APC FNIP1 TNS2 TSC2 SORBS1 CNTLN PPIP5K2 SRRM2 DCP1A

1.11e-0612487117int:YWHAG
InteractionHDAC1 interactions

PPP4R1 CCSAP NCOR2 GAPVD1 RB1 LMO7 TLE4 ZNF516 PITX2 APC SMARCA4 ZNF318 CIT LARP7 DCP1A NPAT

1.14e-0611087116int:HDAC1
InteractionCCDC6 interactions

CYLD PPP4R1 GAPVD1 LMO7 APC SORBS1 MTUS2 NCK2

7.32e-06286718int:CCDC6
InteractionYWHAB interactions

CYLD GAPVD1 DENND4A LMO7 ARHGEF7 EXPH5 APC TNS2 TSC2 SORBS1 CNTLN PPIP5K2 SRRM2 DCP1A

1.00e-0510147114int:YWHAB
InteractionNUP43 interactions

NCOR2 ZC3H13 ASH1L MUC19 APC SMARCA4 ZNF318 SRRM2 CIT LARP7 NPAT

1.10e-056257111int:NUP43
InteractionGSK3A interactions

CYLD ZC3H14 GAPVD1 DENND4A U2SURP APC FNIP1 SRRM2 DCP1A

3.54e-05464719int:GSK3A
InteractionSF3A1 interactions

CYLD ZC3H14 GAPVD1 U2SURP SMARCA4 ZNF318 SRRM2 CIT LARP7

3.97e-05471719int:SF3A1
InteractionBAG2 interactions

CYLD GAPVD1 EXPH5 TLE4 BCORL1 ZNF318 PPIP5K2 SRRM2 CIT LARP7

6.18e-056227110int:BAG2
InteractionDHX8 interactions

ZC3H14 ZC3H13 U2SURP ZNF318 SRRM2 CIT CLASRP

7.51e-05292717int:DHX8
InteractionKDM1A interactions

NCOR2 GAPVD1 RB1 TLE4 ZNF516 BCORL1 ATF7IP2 APC ZNF318 CIT DCP1A NPAT

1.01e-049417112int:KDM1A
InteractionYWHAE interactions

CYLD NCOR2 GAPVD1 DENND4A LMO7 ARHGEF7 EXPH5 APC TNS2 TSC2 SORBS1 CNTLN SRRM2 DCP1A

1.05e-0412567114int:YWHAE
InteractionPABPC1L interactions

CYLD CIT LARP7

1.15e-0427713int:PABPC1L
InteractionCLK3 interactions

ZC3H14 NCOR2 ZC3H13 SRRM2 LARP7 CLASRP

1.25e-04220716int:CLK3
InteractionTERF2IP interactions

ZC3H14 NCOR2 RB1 U2SURP SMARCA4 ZNF318 SRRM2 LARP7 NPAT

1.34e-04552719int:TERF2IP
InteractionPABPC5 interactions

ZC3H14 ATXN2 ZC3H13 U2SURP SRRM2

1.45e-04142715int:PABPC5
InteractionSFN interactions

CYLD GAPVD1 DENND4A LMO7 EXPH5 APC TSC2 SORBS1 SRRM2 DCP1A

1.49e-046927110int:SFN
InteractionRNF6 interactions

AP2A2 LMO7 TNS2 MTUS2

1.50e-0476714int:RNF6
InteractionZYX interactions

CYLD LMO7 ARHGEF7 APC SORBS1 CIT DCP1A

1.58e-04329717int:ZYX
InteractionSYNE3 interactions

CYLD PLEKHG1 NCOR2 LMO7 EXPH5 APC SORBS1 ZNF318

1.65e-04444718int:SYNE3
InteractionPXN interactions

PLEKHG1 AP2A2 ARHGEF7 APC SORBS1 NCK2 DCP1A

1.73e-04334717int:PXN
InteractionKRT23 interactions

CYLD EXPH5 APC

1.75e-0431713int:KRT23
InteractionRBBP4 interactions

CYLD RB1 ASH1L SMARCA4 SRRM2 CIT LARP7 CLASRP NPAT

1.77e-04573719int:RBBP4
InteractionPHF21A interactions

GAPVD1 ZNF516 BCORL1 APC ZNF318 DCP1A NPAT

2.03e-04343717int:PHF21A
GeneFamilyCD molecules|Mucins

MUC19 MUC16

1.35e-0321472648
GeneFamilyAtaxins|Trinucleotide repeat containing

NCOR2 ATXN2

1.91e-0325472775
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND4A FNIP1

1.91e-0325472504
GeneFamilyZinc fingers CCCH-type

ZC3H14 ZC3H13

3.73e-033547273
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

APC ARMCX4

5.58e-0343472409
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG1 ARHGEF7

1.28e-0266472722
CoexpressionGSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_UP

GRHL1 RB1 TLE4 ATF7IP2 ZBTB40 APC FNIP1

1.19e-06200717M7417
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

GAPVD1 ARHGEF7 EXPH5 TLE4 ZNF318 PPIP5K2 LARP7 NPAT

1.53e-06300718M8702
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

ZC3H14 NCOR2 GAPVD1 RB1 ATXN2 MYO9B ARHGEF7 TLE4 U2SURP APC PPIP5K2 NPAT

2.97e-068567112M4500
CoexpressionDING_LUNG_CANCER_MUTATED_FREQUENTLY

RB1 APC IRAK2

4.12e-0612713M16718
CoexpressionGARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_UP

TFEC IRAK2 FNIP1

1.51e-0518713M19133
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000

GAPVD1 SERPINI1 ATXN2 ARHGEF7 ZC3H13 BCORL1 ATF7IP2 ASH1L SMARCA4 FNIP1 ZNF318 SHCBP1L LARP7

1.70e-067957013gudmap_developingGonad_e16.5_ovary_1000
ToppCellNS-moderate-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PPP4R1 GAPVD1 LMO7 EXPH5 ATF7IP2 MUC16

8.06e-0720071664462a18afca3c1a8548a857924b8166058bf958
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DENND4A LMO7 ZNF318 STX7 NCK2

7.51e-06169715c3a6179a64589a370108fea809b157839347759c
ToppCelldroplet-Kidney-nan-18m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB37 EXPH5 BCORL1 PITX2 ARMCX4

9.14e-06176715533d544852038c0612aacf87f4b1c88ff7aace82
ToppCellB_cells-Naive_B_cells_|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

PLEKHG1 ARHGEF7 ZNF318 REM2 NCK2

9.66e-0617871571ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCell(4)_B_cells-(4)_B_mantle|(4)_B_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

TLE4 SCN3A ZNF318 STX7 NCK2

1.10e-0518371521b7fb6482eb1d5d31a4029e47e0992e8ddc8e2c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PLEKHG1 GRHL1 LMO7 CIT PCDH17

1.13e-05184715102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellCOPD-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

PLEKHG1 LMO7 EXPH5 ATF7IP2 SORBS1

1.26e-051887151aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCellBLOOD--(2)_B_cell-(2)_Naive_B_cells|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RB1 SCN3A ZNF318 STX7 NCK2

1.32e-05190715bde288cea27bbdc3ca05737a00fe30a0103a4c74
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PLEKHG1 GRHL1 LMO7 EXPH5 MUC16

1.39e-05192715c15841f35e24d6ef6ce2a9a6dc62e66efdc3d9d5
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPP4R1 PLEKHG1 TFEC DENND4A MYO9B

1.43e-0519371508696a99309f5b088692ddac8cca35413b5e810d
ToppCellsevere-B_cell|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PLEKHG1 SCN3A APC WEE2 STX7

1.50e-051957150fc3c605609c9e6bdea15d73c45def2188ae5fb1
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 GRHL1 LMO7 RNF39 CIT

1.61e-05198715af399569c718f5fd971d73a7926768c9311002a3
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 GRHL1 LMO7 RNF39 CIT

1.61e-051987151408e02e053ad3406229bfe8189da03be6366e81
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPP4R1 PLEKHG1 DENND4A MYO9B

1.34e-041637146bed27d2f67a430a847da5eb47878d14b4949c45
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF7 PLEKHG1 MYO9B SHCBP1L

1.40e-041657147c771f22b58989572c939ed127e637ec28dc0dca
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLEKHG1 SCN3A ZNF318 STX7

1.40e-04165714fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

PLEKHG1 GRHL1 LMO7 CIT

1.57e-04170714269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRHL1 GLRA3 MUC19 PCDH17

1.60e-04171714fdd96c6fe850bd10e1e0d0f18c4401f8348b7d2c
ToppCell3'_v3-blood-Lymphocytic_B-Naive_B_cells|blood / Manually curated celltypes from each tissue

PLEKHG1 SCN3A ZNF318 STX7

1.64e-04172714f16f90d17feac1ee52fd513907b28456865fd31d
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCSAP BCORL1 CNTLN PCDH17

1.72e-041747149d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCSAP BCORL1 CNTLN PCDH17

1.72e-0417471453cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LMO7 MYO9B MRC2 REM2

1.75e-0417571412f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO7 TLE4 ASH1L SRRM2

1.87e-0417871401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRHL1 LMO7 CIT PCDH17

1.87e-04178714f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRHL1 LMO7 MUC16 CMYA5

1.91e-041797146e965e424eebef50f0202cff75f458be395cfca1
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

GRHL1 SERPINI1 GLRA3 RNF39

1.95e-04180714b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLEKHG1 IRAK2 SORBS1 PCDH17

1.95e-04180714d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCellB_cells-Naive_B_cells_|World / Immune cells in Kidney/Urine in Lupus Nephritis

PLEKHG1 SCN3A ZNF318 STX7

2.04e-0418271463c3b63315276b66667d49fab09661ac320e7a36
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

LMO7 SORBS1 CMYA5 MTUS2

2.04e-04182714287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PLEKHG1 SCN3A ZNF318 STX7

2.08e-04183714dbc7ec66da5930c2bf4e0405937b054e04c22a34
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 TLE4 SORBS1 PCDH17

2.08e-04183714e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_progenitors|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GRHL1 LMO7 EXPH5 MUC16

2.12e-04184714fcb5dd4fb3fa79f3b6029fad32a474cacde35a3b
ToppCellCOPD-Endothelial-VE_Capillary_A|COPD / Disease state, Lineage and Cell class

PLEKHG1 EXPH5 SORBS1 PCDH17

2.12e-041847145f4f7775d488ececf086c71441defecbee9d8a9c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

PLEKHG1 GRHL1 LMO7 CIT

2.17e-04185714673f0c688ae6984bc8027df2da335787924f4137
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

PLEKHG1 GRHL1 LMO7 CIT

2.17e-0418571498b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellControl-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

PLEKHG1 GRHL1 TLE4 RNF39

2.17e-041857146814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

LMO7 SORBS1 CMYA5 MTUS2

2.17e-041857146baccb26f999145e51b91d94315bf8d4655bef31
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 TLE4 SORBS1 PCDH17

2.26e-04187714ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

PLEKHG1 GRHL1 SERPINI1 RNF39

2.26e-04187714ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-B_lymphocytic-naive_B_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PLEKHG1 SCN3A ZNF318 STX7

2.26e-04187714160e5f338537d90d50f863a1be801b1071ac7da7
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLEKHG1 TLE4 SORBS1 PCDH17

2.26e-0418771497b2463fb37e7196dd2f92553acf8e7bc3ec40dd
ToppCellnormal-na-Lymphocytic_B-B_naive-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

PLEKHG1 RB1 SCN3A STX7

2.31e-04188714ec72ba73b10c6f2ff39699b6b46b90a3e95a4c24
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLEKHG1 SCN3A ZNF318 STX7

2.31e-04188714d8decd9b5967873ca8320c2f9f07365f163c777f
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Striatum / BrainAtlas - Mouse McCarroll V32

CYLD CCSAP SCN3A REM2

2.31e-04188714e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

LMO7 SORBS1 CMYA5 MTUS2

2.35e-041897145e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PLEKHG1 SCN3A ZNF318 STX7

2.35e-04189714e2bb5900d210386b7b74938e7a3636d0c7ba1bcf
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 TLE4 SORBS1 PCDH17

2.35e-041897145d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

PLEKHG1 GRHL1 SERPINI1 RNF39

2.40e-04190714756bff697d30aec56c0ebfca94295f084a15bf37
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLEKHG1 SCN3A ZNF318 STX7

2.40e-04190714112706d64ee73b55dcf76f33ca064ab1fc6ce87f
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Naive_B_cells|bone_marrow / Manually curated celltypes from each tissue

PLEKHG1 SCN3A ZNF318 STX7

2.40e-041907143d45d5011305f13634013d9eeb98f235517dd54e
ToppCelldroplet-Fat-Scat-21m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHG1 LMO7 SORBS1 PCDH17

2.40e-04190714d3e46cf800a07ca9b01c78192962d223b9785d05
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

LMO7 SORBS1 CMYA5 MTUS2

2.40e-04190714de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellCOVID_vent-Lymphocytic-B_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

PLEKHG1 SCN3A ZNF318 STX7

2.40e-0419071440b5e9e8f8fd8d84cb5b43e67b49267082348e9f
ToppCellCOVID_vent-Lymphocytic-B_cell-|COVID_vent / Disease condition, Lineage, Cell class and subclass

PLEKHG1 SCN3A ZNF318 STX7

2.40e-04190714a37a32dc1b931562a6660074e19d5598efc65284
ToppCelldroplet-Fat-Scat-21m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHG1 LMO7 SORBS1 PCDH17

2.40e-04190714dd89ef1ecea20b2f6fbdc6cea4ca41b28b3ed822
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PLEKHG1 SCN3A ZNF318 STX7

2.40e-04190714a7498fe55b7810c482291db782dc5282675d246a
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

LMO7 SORBS1 CMYA5 MTUS2

2.40e-04190714fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

LMO7 SORBS1 CMYA5 MTUS2

2.45e-0419171425f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PLEKHG1 GRHL1 LMO7 EXPH5

2.45e-0419171460ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

LMO7 SORBS1 CMYA5 MTUS2

2.45e-041917145d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

PLEKHG1 GRHL1 LMO7 RNF39

2.45e-0419171423776c7302cead3881b39127398f3b3e0d27885e
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PLEKHG1 SCN3A ZNF318 STX7

2.45e-04191714b374676ac90572d65895052d46469906e2b6fd93
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLEKHG1 DENND4A SCN3A STX7

2.50e-04192714446c61c0d6ba89c619efe87ee495951299953981
ToppCell10x5'-bone_marrow-Lymphocytic_B-Naive_B_cells|bone_marrow / Manually curated celltypes from each tissue

PLEKHG1 SCN3A ZNF318 STX7

2.50e-04192714fa99243ff028498c6a67d207a93e02c48e69cd42
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PLEKHG1 SCN3A ZNF318 STX7

2.50e-04192714800edadd1d1ba6b7e0a0398030dd4b61c9c480c7
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

LMO7 SORBS1 CMYA5 MTUS2

2.55e-04193714dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

PLEKHG1 GRHL1 LMO7 RNF39

2.55e-041937142bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RANBP10 GRHL1 DENND4A SORBS1

2.55e-04193714305e15ee467826ee08b2617c69f250ad39c11b19
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 TLE4 SORBS1 PCDH17

2.55e-04193714aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-Naive_B_cells|lymph-node_spleen / Manually curated celltypes from each tissue

PLEKHG1 SCN3A ZNF318 STX7

2.55e-04193714eb497d62a45ad77b2578b03a84cb3edc83207be5
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 TLE4 SORBS1 PCDH17

2.55e-04193714c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellCOVID_non-vent-Lymphocytic-B_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

PLEKHG1 SCN3A ZNF318 STX7

2.55e-0419371432d139f922cd19adc1cc1e0e9a828115be9945d6
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 TLE4 SORBS1 PCDH17

2.55e-04193714a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCellnormal-na-Lymphocytic_B-B_naive-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

PLEKHG1 SCN3A ZNF318 STX7

2.55e-04193714dd199163fc13f3d411fe741cf003237064349e22
ToppCellPCW_05-06-Epithelial-Epithelial_airway|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PLEKHG1 GRHL1 LMO7 EXPH5

2.55e-04193714af6ec2c2ba92aef3e41531c3c7215b3300437bd9
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

PLEKHG1 ARHGEF7 SORBS1 PCDH17

2.55e-04193714479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCellCOVID_non-vent-Lymphocytic-B_cell-|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

PLEKHG1 SCN3A ZNF318 STX7

2.55e-0419371491955c3773c9729a96e82f240f06b072367970d9
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RANBP10 GRHL1 DENND4A SORBS1

2.55e-04193714dd376664906caccc9c2065f8e7a364509e18a5cc
ToppCellsevere_influenza-B_naive|severe_influenza / disease group, cell group and cell class (v2)

PLEKHG1 SCN3A ATF7IP2 NCK2

2.60e-041947147c1e9ce5de3bb1657a67010de673c8bb60129cb6
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF516 SMARCA4 DISP2 SRRM2

2.60e-041947143a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B-Naive_B_cells|lymph-node_spleen / Manually curated celltypes from each tissue

PLEKHG1 SCN3A ZNF318 STX7

2.60e-0419471420967afbadb3cf80ba9f4d7ebda4e64389252e70
ToppCellsevere-B_cell|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PLEKHG1 SCN3A APC WEE2

2.60e-041947142fee6083fb56b16d1f04fd0b92ec622fd26ba3fa
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PLEKHG1 ZNF318 STX7 SRRM2

2.60e-04194714ff661419b697aef51a53fdeac8d37d870d65f491
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO7 ASH1L SORBS1 PCDH17

2.60e-04194714e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

LMO7 SORBS1 CMYA5 MTUS2

2.60e-0419471489812fb164065041357bb37a3c2d87028ec3de4e
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPP4R1 PLEKHG1 DENND4A RB1

2.60e-04194714d852aebf7a763b9a776c4570711f0c759f591910
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PLEKHG1 GRHL1 LMO7 EXPH5

2.60e-04194714b19e16a76d7342ff9a665d19c9151652916f17d4
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

LMO7 SORBS1 CMYA5 MTUS2

2.60e-04194714c3535f7cc0076653c72db582047cff053c322397
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF516 SMARCA4 DISP2 SRRM2

2.60e-041947140b023de48ed8a550d169bbe954881eb04bf4f981
ToppCellILEUM-inflamed-(2)_B_cell-(2)_Naive_B_cells|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RB1 ZNF318 STX7 NCK2

2.60e-04194714a89e67a40382600739be92e395bf47dd44aa4122
ToppCellASK452-Endothelial-Lymphatic|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq

RANBP10 ZC3H14 SCN3A SLC24A1

2.65e-0419571420f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

LMO7 SORBS1 CMYA5 MTUS2

2.65e-04195714f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLEKHG1 DENND4A SCN3A STX7

2.65e-041957140c49d22c348aec6d8a1a976e7c88d0a3b48a4244
ToppCellsevere-Lymphocytic-B_cells_1|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PLEKHG1 SCN3A ZNF318 STX7

2.65e-0419571473e39005a597e13aea571ae6ae5824d1c7448b71
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

LMO7 SORBS1 CMYA5 MTUS2

2.65e-0419571475fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal-CFuPNs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

SERPINI1 LMO7 TLE4 PCDH17

2.65e-04195714574354ef4bcefeb9856b65d19bb92e2cffe5dc7a
ToppCellInfluenza_Severe-B_naive|Influenza_Severe / Disease group and Cell class

PLEKHG1 SCN3A ATF7IP2 NCK2

2.65e-04195714a25516ed670c7738670ffbaa6f7cd167946f3825
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PLEKHG1 GRHL1 LMO7 RNF39

2.65e-04195714dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF516 ASH1L FNIP1 SRRM2

2.65e-041957143e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF516 ASH1L FNIP1 SRRM2

2.65e-041957147796ea9247f4c63762f0de8490fed08b9717fa23
DrugDiloxanide furoate [3736-81-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A

RB1 ZC3H13 ZNF516 ZBTB40 DOK2 SRRM2 PCDH17

1.92e-061877175025_UP
DrugGallamine triethiodide [65-29-2]; Up 200; 4.4uM; HL60; HG-U133A

RANBP10 ATXN2 MYO9B MRC2 ZC3H13 ZBTB40 TSC2

2.91e-061997171375_UP
DrugNetilmicin sulfate [56931-57-2]; Down 200; 2.8uM; MCF7; HT_HG-U133A

AP2A2 ARHGEF7 BCORL1 ATF7IP2 APC NCK2 NPAT

3.00e-062007176005_DN
DrugLasalocid sodium salt [25999-20-6]; Down 200; 6.6uM; PC3; HT_HG-U133A

NCOR2 AP2A2 LMO7 MRC2 TLE4 APC

3.02e-051927166639_DN
Drugradicicol; Up 200; 0.1uM; PC3; HG-U133A

GAPVD1 SERPINI1 ZC3H13 ZBTB40 DCP1A NPAT

3.30e-05195716449_UP
DrugChlorthalidone [77-36-1]; Down 200; 11.8uM; PC3; HT_HG-U133A

SERPINI1 MYO9B U2SURP ASH1L APC ZNF318

3.30e-051957167152_DN
DrugBenzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; HL60; HT_HG-U133A

RANBP10 AP2A2 RB1 SMARCA4 SLC24A1 CIT

3.39e-051967166155_DN
DrugOxybenzone [131-57-7]; Down 200; 17.6uM; PC3; HT_HG-U133A

LMO7 MYO9B ZBTB40 APC ZNF318 SLC24A1

3.39e-051967166309_DN
DrugSerotonin hydrochloride [153-98-0]; Up 200; 18.8uM; PC3; HT_HG-U133A

RB1 MYO9B MRC2 TLE4 ZBTB40 ST7L

3.39e-051967164673_UP
DrugParoxetine maleate [64006-44-6]; Down 200; 1uM; PC3; HT_HG-U133A

MYO9B ARHGEF7 U2SURP ZBTB40 SLC24A1 SRRM2

3.49e-051977164556_DN
DrugTTNPB; Up 200; 0.1uM; PC3; HG-U133A

SERPINI1 MRC2 ZBTB40 ST7L DCP1A NPAT

3.49e-05197716451_UP
DrugNicergoline; Down 200; 8.2uM; PC3; HT_HG-U133A

CYLD RANBP10 DENND4A AP2A2 LMO7 MYO9B

3.49e-051977165775_DN
DrugAllantoin [97-59-6]; Up 200; 25.2uM; HL60; HT_HG-U133A

CYLD MRC2 ZBTB40 APC PCDH17 NPAT

3.49e-051977161842_UP
DrugGossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A

NCOR2 SERPINI1 AP2A2 MYO9B TLE4 ZBTB40

3.59e-051987164762_DN
DrugPargyline hydrochloride [306-07-0]; Down 200; 20.4uM; MCF7; HT_HG-U133A

MYO9B ARHGEF7 U2SURP BCORL1 APC NPAT

3.59e-051987167016_DN
DrugIsoxicam [34552-84-6]; Down 200; 12uM; MCF7; HT_HG-U133A

AP2A2 MYO9B ARHGEF7 EXPH5 TLE4 ZBTB40

3.59e-051987167028_DN
DrugDiazoxide [364-98-7]; Up 200; 17.4uM; MCF7; HT_HG-U133A

AP2A2 MYO9B MRC2 SORBS1 DOK2 SLC24A1

3.59e-051987162214_UP
DrugTorsemide [56211-40-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A

RANBP10 MYO9B APC ZNF318 SLC24A1 SRRM2

3.59e-051987165476_DN
DrugGuanethidine sulfate [60-02-6]; Down 200; 13.4uM; HL60; HG-U133A

ZC3H14 DENND4A ATXN2 SMARCA4 TSEN2 NPAT

3.69e-051997161554_DN
DrugZoxazolamine [61-80-3]; Up 200; 23.8uM; MCF7; HT_HG-U133A

RANBP10 MYO9B MRC2 ZC3H13 DOK2 PCDH17

3.69e-051997162625_UP
DrugBendroflumethiazide [73-48-3]; Up 200; 9.4uM; HL60; HT_HG-U133A

AP2A2 EXPH5 MRC2 CNTLN SLC24A1 PCDH17

3.69e-051997162555_UP
DrugVancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; MCF7; HT_HG-U133A

AP2A2 EXPH5 TLE4 U2SURP PITX2 TNS2

3.69e-051997162858_DN
DrugHelveticoside [630-64-8]; Down 200; 7.4uM; HL60; HT_HG-U133A

ZNF7 ZC3H14 U2SURP SLC24A1 TSEN2

2.90e-041867152192_DN
Drug0179445-0000 [211246-22-9]; Down 200; 10uM; PC3; HT_HG-U133A

DENND4A ATF7IP2 TNS2 SORBS1 SLC24A1

3.12e-041897153733_DN
Drug2-propylpentanoic acid; Up 200; 10000uM; HL60; HG-U133A

CYLD RANBP10 SERPINI1 MYO9B NPAT

3.20e-04190715410_UP
DrugLanatoside C [17575-22-3]; Down 200; 4uM; HL60; HT_HG-U133A

ZNF7 ZC3H14 U2SURP SLC24A1 TSEN2

3.20e-041907152193_DN
DrugDigoxigenin [1672-46-4]; Down 200; 10.2uM; HL60; HT_HG-U133A

ZNF7 ZC3H14 U2SURP SLC24A1 TSEN2

3.20e-041907153060_DN
Drugthioridazine hydrochloride; Down 200; 10uM; PC3; HT_HG-U133A

AP2A2 U2SURP SMARCA4 SLC24A1 SRRM2

3.28e-041917154454_DN
DrugStrophantine octahydrate [11018-89-6]; Down 200; 5.4uM; HL60; HT_HG-U133A

ZNF7 ZC3H14 U2SURP ZNF318 STX7

3.28e-041917151302_DN
Drugnortropanol

CYLD GLRA3

3.40e-049712CID000068147
DrugBisacodyl [603-50-9]; Down 200; 11uM; PC3; HT_HG-U133A

ZNF7 CYLD MYO9B U2SURP SRRM2

3.44e-041937154616_DN
DrugCanrenoic acid potassium salt [2181-04-6]; Down 200; 10uM; MCF7; HT_HG-U133A

RB1 MYO9B ZNF516 ZBTB40 TNS2

3.44e-041937156783_DN
DrugPhenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; PC3; HT_HG-U133A

NCOR2 RB1 LMO7 APC SORBS1

3.44e-041937156699_DN
DrugTalampicillin hydrochloride [39878-70-1]; Down 200; 7.8uM; MCF7; HT_HG-U133A

U2SURP APC TSC2 STX7 SLC24A1

3.44e-041937157014_DN
DrugDoxycycline hydrochloride [10592-13-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A

ARHGEF7 EXPH5 BCORL1 ZBTB40 APC

3.44e-041937153479_DN
DrugButirosin disulfate salt [51022-98-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A

AP2A2 RB1 MYO9B APC TNS2

3.52e-041947156779_DN
DrugEthoxyquin [91-53-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A

NCOR2 RB1 TLE4 ST7L SLC24A1

3.52e-041947153846_UP
DrugCinchonine [118-10-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A

CYLD RB1 MYO9B MRC2 ZBTB40

3.52e-041947152789_UP
DrugAlexidine dihydrochloride [22573-93-9]; Down 200; 6.8uM; MCF7; HT_HG-U133A

AP2A2 MYO9B U2SURP PITX2 SRRM2

3.52e-041947154721_DN
DrugPindolol [13523-86-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A

RANBP10 PITX2 APC TNS2 ZNF318

3.52e-041947152238_DN
DrugSkimmianine [83-95-4]; Down 200; 15.4uM; HL60; HT_HG-U133A

DENND4A ARHGEF7 U2SURP BCORL1 APC

3.52e-041947152504_DN
Drugphentolamine; Down 200; 11.5uM; MCF7; HT_HG-U133A_EA

ZBTB40 SLC24A1 CLASRP DCP1A NPAT

3.61e-041957151138_DN
DrugTriflusal [322-79-2]; Down 200; 16.2uM; MCF7; HT_HG-U133A

RB1 MYO9B EXPH5 APC NPAT

3.61e-041957152867_DN
DrugHecogenin [467-55-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A

TLE4 ZNF516 BCORL1 ASH1L ZBTB40

3.61e-041957153457_DN
DrugHomosalate [118-56-9]; Down 200; 15.2uM; PC3; HT_HG-U133A

CYLD RANBP10 MYO9B U2SURP TSC2

3.61e-041957154533_DN
DrugMefenamic acid [61-68-7]; Down 200; 16.6uM; PC3; HT_HG-U133A

RANBP10 DENND4A EXPH5 U2SURP ASH1L

3.61e-041957155109_DN
DrugBicuculline (+) [485-49-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A

RB1 ZC3H13 APC CNTLN SLC24A1

3.61e-041957152796_UP
DrugQuinacrine dihydrochloride dihydrate [6151-30-0]; Down 200; 7.8uM; MCF7; HT_HG-U133A

CYLD MYO9B U2SURP PITX2 APC

3.61e-041957153179_DN
DrugQuinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A

CYLD AP2A2 U2SURP PITX2 SRRM2

3.61e-041957153191_DN
Drughaloperidol; Down 200; 10uM; MCF7; HT_HG-U133A_EA

AP2A2 MYO9B EXPH5 ZBTB40 TNS2

3.69e-041967151024_DN
DrugEdrophonium chloride [116-38-1]; Down 200; 19.8uM; HL60; HG-U133A

RANBP10 DENND4A TLE4 U2SURP SRRM2

3.69e-041967152019_DN
DrugTetracycline hydrochloride [64-75-5]; Up 200; 8.4uM; PC3; HT_HG-U133A

NCOR2 TFEC AP2A2 MRC2 ZNF516

3.69e-041967155757_UP
DrugOxolinic acid [14698-29-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A

ZBTB40 APC TSC2 ZNF318 CIT

3.69e-041967155519_DN
DrugDelcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A

SERPINI1 AP2A2 APC DOK2 SLC24A1

3.69e-041967153613_DN
DrugTrimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; PC3; HT_HG-U133A

MRC2 TLE4 U2SURP ASH1L APC

3.69e-041967154100_DN
DrugPraziquantel [55268-74-1]; Down 200; 12.8uM; MCF7; HT_HG-U133A

TLE4 BCORL1 ASH1L ZBTB40 APC

3.69e-041967157228_DN
DrugMeclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; PC3; HT_HG-U133A

DENND4A AP2A2 LMO7 ATF7IP2 SRRM2

3.69e-041967156637_DN
DrugCetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; PC3; HT_HG-U133A

MYO9B GLRA3 APC SLC24A1 PCDH17

3.69e-041967154231_UP
DrugTriflupromazine hydrochloride [1098-60-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A

CYLD AP2A2 EXPH5 BCORL1 DCP1A

3.69e-041967151691_DN
DrugCefoperazone dihydrate; Down 200; 5.8uM; PC3; HT_HG-U133A

CYLD NCOR2 DENND4A APC ZNF318

3.69e-041967156323_DN
DrugDeptropine citrate [2169-75-7]; Up 200; 7.6uM; HL60; HT_HG-U133A

RANBP10 NCOR2 MYO9B SMARCA4 SRRM2

3.69e-041967153144_UP
DrugMoricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; MCF7; HT_HG-U133A

AP2A2 EXPH5 APC ZNF318 CNTLN

3.69e-041967156000_UP
DrugIpratropium bromide [22254-24-6]; Up 200; 9.8uM; PC3; HT_HG-U133A

LMO7 ZNF516 APC CNTLN SLC24A1

3.78e-041977155823_UP
DrugMeclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; MCF7; HT_HG-U133A

AP2A2 BCORL1 APC TNS2 SRRM2

3.78e-041977153277_DN
DrugMethylatropine nitrate [52-88-0]; Down 200; 11uM; PC3; HT_HG-U133A

ZC3H14 AP2A2 ZBTB40 TSC2 ZNF318

3.78e-041977157253_DN
Drug2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A

NCOR2 MYO9B U2SURP TNS2 NPAT

3.78e-041977155211_DN
DrugMebendazole [31431-39-7]; Down 200; 13.6uM; MCF7; HT_HG-U133A

DENND4A PITX2 ASH1L ZNF318 NPAT

3.78e-041977152300_DN
Drugalpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A

NCOR2 ZC3H13 APC ST7L SLC24A1

3.78e-041977155207_UP
DrugRibostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; MCF7; HT_HG-U133A

CYLD ZC3H14 AP2A2 U2SURP ZBTB40

3.78e-041977153444_DN
DrugL(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A

CYLD NCOR2 ZNF318 SLC24A1 PCDH17

3.78e-041977156497_UP
DrugChloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A

CYLD AP2A2 CNTLN SLC24A1 PCDH17

3.78e-041977153350_UP
DrugCefotiam hydrochloride; Down 200; 7.2uM; MCF7; HT_HG-U133A

CYLD U2SURP ASH1L TNS2 SRRM2

3.78e-041977155361_DN
Drug(S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; MCF7; HT_HG-U133A

NCOR2 AP2A2 MRC2 BCORL1 APC

3.78e-041977153870_DN
DrugProcyclidine hydrochloride [1508-76-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A

CYLD AP2A2 ZC3H13 SORBS1 SLC24A1

3.87e-041987153330_UP
DrugAmitryptiline hydrochloride [549-18-8]; Down 200; 12.8uM; PC3; HT_HG-U133A

AP2A2 ATF7IP2 APC SMARCA4 TSC2

3.87e-041987156353_DN
DrugCarteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; PC3; HT_HG-U133A

TFEC MYO9B ZNF516 PITX2 PCDH17

3.87e-041987154096_UP
DrugMeprylcaine hydrochloride [956-03-6]; Up 200; 14.8uM; PC3; HT_HG-U133A

AP2A2 RB1 PITX2 GLRA3 APC

3.87e-041987155723_UP
DrugNabumetone [42924-53-8]; Up 200; 17.6uM; MCF7; HT_HG-U133A

CYLD TLE4 ZNF318 DOK2 PCDH17

3.87e-041987156487_UP
DrugKawain [500-64-1]; Down 200; 17.4uM; HL60; HT_HG-U133A

MRC2 BCORL1 ATF7IP2 ZBTB40 APC

3.87e-041987152337_DN
DrugHeptaminol hydrochloride [543-15-7]; Down 200; 22uM; PC3; HT_HG-U133A

SERPINI1 AP2A2 MYO9B BCORL1 SRRM2

3.87e-041987157313_DN
DrugEtodolac [41340-25-4]; Down 200; 14uM; MCF7; HT_HG-U133A

ARHGEF7 EXPH5 TLE4 U2SURP ZBTB40

3.87e-041987157006_DN
DrugTolmetin sodium salt dihydrate [64490-92-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A

MYO9B EXPH5 ZBTB40 APC SRRM2

3.87e-041987153347_DN
DrugCP-690334-01 [459212-38-5]; Up 200; 1uM; MCF7; HT_HG-U133A

CYLD SERPINI1 RB1 ZC3H13 MINAR1

3.87e-041987154383_UP
Drugestradiol, USP; Up 200; 0.01uM; HL60; HT_HG-U133A

CYLD NCOR2 EXPH5 SORBS1 ST7L

3.87e-041987156200_UP
DrugPhenethicillin potassium salt [132-93-4]; Up 200; 10uM; PC3; HT_HG-U133A

DENND4A RB1 MYO9B MRC2 SLC24A1

3.87e-041987155763_UP
DrugYohimbine hydrochloride [65-19-0]; Up 200; 10.2uM; MCF7; HT_HG-U133A

CYLD AP2A2 ASH1L APC NPAT

3.87e-041987152755_UP
DrugClioquinol [130-26-7]; Down 200; 13uM; MCF7; HT_HG-U133A

AP2A2 MYO9B ZC3H13 ZBTB40 APC

3.87e-041987155258_DN
DrugFlumequine [42835-25-6]; Up 200; 15.4uM; PC3; HT_HG-U133A

NCOR2 GLRA3 APC SORBS1 SLC24A1

3.87e-041987155104_UP
DrugGriseofulvin [126-07-8]; Up 200; 11.2uM; HL60; HT_HG-U133A

AP2A2 ARHGEF7 ZC3H13 BCORL1 SRRM2

3.87e-041987152332_UP
DrugDisopyramide [3737-09-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A

RANBP10 AP2A2 ZNF516 ZNF318 SRRM2

3.87e-041987157035_UP
DrugKarakoline [39089-30-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A

NCOR2 LMO7 MRC2 GLRA3 MINAR1

3.87e-041987153638_UP
DrugChloroquine diphosphate [50-63-5]; Up 200; 7.8uM; HL60; HG-U133A

ZC3H13 U2SURP BCORL1 ZNF318 NPAT

3.87e-041987151719_UP
DrugIsoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; HL60; HG-U133A

CYLD NCOR2 MYO9B BCORL1 PCDH17

3.87e-041987151985_UP
DrugDiflunisal [22494-42-4]; Up 200; 16uM; PC3; HT_HG-U133A

RB1 TLE4 SCN3A APC ST7L

3.96e-041997154210_UP
DrugIsoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; MCF7; HT_HG-U133A

NCOR2 TLE4 ZC3H13 DOK2 SLC24A1

3.96e-041997154810_UP
DrugChlorphensin carbamate [886-74-8]; Up 200; 16.2uM; HL60; HG-U133A

MYO9B EXPH5 ZBTB40 TSC2 DOK2

3.96e-041997151432_UP
DrugPiretanide [55837-27-9]; Up 200; 11uM; MCF7; HT_HG-U133A

RB1 MYO9B MRC2 SORBS1 SLC24A1

3.96e-041997156828_UP
DrugProglumide [6620-60-6]; Up 200; 12uM; PC3; HT_HG-U133A

MYO9B MRC2 TLE4 ZC3H13 SLC24A1

3.96e-041997153780_UP
DrugEpirizole [18694-40-1]; Up 200; 17uM; MCF7; HT_HG-U133A

NCOR2 RB1 MYO9B EXPH5 SCN3A

3.96e-041997155995_UP
DrugRetrorsine [480-54-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A

CYLD AP2A2 RB1 APC ZNF318

3.96e-041997154946_UP
Diseaseimmunoglobulin superfamily DCC subclass member 4 measurement

DENND4A SLC24A1

5.52e-055702EFO_0801690
Diseaseplatelet component distribution width

NCOR2 TFEC GAPVD1 ATXN2 MYO9B U2SURP DOK2 ST7L NCK2

7.23e-05755709EFO_0007984
DiseaseIntellectual Disability

ZC3H14 SCN3A ASH1L ZBTB40 APC TSEN2 LARP7

9.20e-05447707C3714756
Diseasecardiovascular disease

PLEKHG1 ATXN2 MYO9B PITX2 SMARCA4 SORBS1 ZNF318

1.06e-04457707EFO_0000319
Diseaseimmature platelet fraction

PPP4R1 MYO9B SORBS1 ST7L

1.59e-04114704EFO_0009187
Diseasediastolic blood pressure, alcohol drinking

PLEKHG1 SLC39A12 ATXN2 ST7L

1.82e-04118704EFO_0004329, EFO_0006336
DiseaseCarcinoma, Small Cell

RB1 SMARCA4

1.98e-049702C0262584
Diseasemedulloblastoma (is_implicated_in)

APC TSC2

2.47e-0410702DOID:0050902 (is_implicated_in)
DiseaseMental Retardation, Psychosocial

ZBTB40 APC TSEN2 LARP7

3.40e-04139704C0025363
DiseaseProfound Mental Retardation

ZBTB40 APC TSEN2 LARP7

3.40e-04139704C0020796
DiseaseMental deficiency

ZBTB40 APC TSEN2 LARP7

3.40e-04139704C0917816
DiseaseAnimal Mammary Neoplasms

RB1 MRC2 TLE4 APC

3.68e-04142704C0024667
DiseaseMammary Carcinoma, Animal

RB1 MRC2 TLE4 APC

3.68e-04142704C1257925
Diseaseplatelet crit

TFEC ATXN2 MYO9B EXPH5 TLE4 U2SURP ZNF318 ST7L NPAT

4.07e-04952709EFO_0007985
Diseasereceptive language perception, parental genotype effect measurement

PLEKHG1 MUC19

4.96e-0414702EFO_0005686, EFO_0005939
DiseaseNon-Small Cell Lung Carcinoma

CYLD RB1 APC SMARCA4

5.25e-04156704C0007131
DiseaseIschemic stroke, tissue plasminogen activator measurement

ATXN2 PITX2

5.71e-0415702EFO_0004791, HP_0002140
Diseaselevel of Sterol ester (27:1/18:1) in blood serum

SMARCA4 CLASRP

6.52e-0416702OBA_2045195
DiseaseIschemic stroke, plasminogen activator inhibitor 1 measurement

ATXN2 PITX2

6.52e-0416702EFO_0004792, HP_0002140
Diseasefactor XI measurement, Ischemic stroke

ATXN2 PITX2

7.37e-0417702EFO_0004694, HP_0002140
Diseaseintellectual disability (implicated_via_orthology)

ZC3H14 RB1 ATF7IP2

7.64e-0475703DOID:1059 (implicated_via_orthology)
Diseasereticulocyte count

DENND4A ATXN2 MYO9B U2SURP ASH1L ZBTB40 RNF39 STX7 TSEN2

7.93e-041045709EFO_0007986
Diseasehypertension

NCOR2 SLC39A12 ATXN2 MYO9B ZNF318

8.22e-04307705EFO_0000537
Diseasefactor VIII measurement, Ischemic stroke

ATXN2 PITX2

9.24e-0419702EFO_0004630, HP_0002140
Diseasediastolic blood pressure, systolic blood pressure

RANBP10 SLC39A12 GAPVD1 ATXN2 MRC2 GLRA3 DCP1A

1.05e-03670707EFO_0006335, EFO_0006336
DiseaseSarcoma

RB1 SMARCA4

1.13e-0321702C1261473
Diseasemean arterial pressure

PLEKHG1 ATXN2 MYO9B TNS2 ZNF318 ST7L

1.19e-03499706EFO_0006340
Diseaseanxiety disorder (implicated_via_orthology)

SCN3A TSC2

1.24e-0322702DOID:2030 (implicated_via_orthology)
DiseaseSjogren's syndrome (is_marker_for)

MUC19 MUC16

1.48e-0324702DOID:12894 (is_marker_for)
Diseasebreast cancer (implicated_via_orthology)

APC SMARCA4

1.61e-0325702DOID:1612 (implicated_via_orthology)
Diseasemean arterial pressure, alcohol drinking

PLEKHG1 ATXN2 ST7L

1.66e-0398703EFO_0004329, EFO_0006340
Diseaselevel of Sterol ester (27:1/18:2) in blood serum

SMARCA4 CLASRP

1.74e-0326702OBA_2045194
Diseaselevel of Sterol ester (27:1/16:0) in blood serum

SMARCA4 CLASRP

1.74e-0326702OBA_2045191
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

APC SMARCA4

1.74e-0326702C0009405
DiseasePancreatic Neoplasm

RB1 APC TSC2

1.75e-03100703C0030297
DiseaseMalignant neoplasm of pancreas

RB1 APC TSC2

1.86e-03102703C0346647
DiseaseNephrotic Syndrome

TNS2 NCK2

1.87e-0327702C0027726
DiseaseSezary Syndrome

RB1 SMARCA4

1.87e-0327702C0036920
DiseaseHereditary Nonpolyposis Colorectal Cancer

APC SMARCA4

2.16e-0329702C1333990
DiseaseIschemic stroke, factor VII measurement

ATXN2 PITX2

2.16e-0329702EFO_0004619, HP_0002140
Diseasediastolic blood pressure, unipolar depression

PLEKHG1 ATXN2

2.31e-0330702EFO_0003761, EFO_0006336
DiseaseIschemic stroke, von Willebrand factor measurement

ATXN2 PITX2

2.31e-0330702EFO_0004629, HP_0002140

Protein segments in the cluster

PeptideGeneStartEntry
ESTNCSPTRKRSSSE

ASH1L

1676

Q9NR48
KRSRSLSPKSSFTDS

CNTLN

511

Q9NXG0
TPSKSRSASSEEASE

BCORL1

1461

Q5H9F3
RKPSDEEFASRKSTA

ARHGEF7

691

Q14155
QTRTRETDKSPTSTE

CCSAP

136

Q6IQ19
VTRSSDLERKASSPS

DCP1A

511

Q9NPI6
RRSPSFDTSTATSKL

DISP2

1171

A7MBM2
PSSRRKESSTPEEFS

CIT

1336

O14578
VSRPDDKDEATTASR

ARMCX4

1756

Q5H9R4
PSTVTDLEDTKRDRS

AP2A2

621

O94973
SGRSEARESKEVTTS

MTUS2

491

Q5JR59
DSKSISTPSARRDLA

DENND4A

1191

Q7Z401
DSIDSFETQRTPRKS

RB1

346

P06400
SEVRSLSSRSPKSQD

RANBP10

346

Q6VN20
SSTFKDPERASLRDS

PCDH17

876

O14917
VATKETDSARSRSAP

GLRA3

26

O75311
IIKAPSSRRFSEDSS

NPAT

1286

Q14207
SPRLRESSTSEKTSS

MUC16

5486

Q8WXI7
TKPTTTSSSERERDR

NCOR2

1786

Q9Y618
SSPRDTSAFFLETKE

DOK2

76

O60496
RDSESSPSDFSVSLK

NCK2

311

O43639
GTERRKEDTPTSSRT

SLC24A1

136

O60721
RSDLPTSSDSKDFST

IRAK2

166

O43187
SNRAVTPSSEAKDSR

ATXN2

736

Q99700
STSDDTDVREVSSRP

GAPVD1

746

Q14C86
TKTSVEESRTTRPSA

MUC19

6101

Q7Z5P9
DSTTFAKREDRVTTE

LMO7

846

Q8WWI1
RYSRSSSSPTEATEK

MRC2

1451

Q9UBG0
PSTTVFSRRSPSDKD

EXPH5

901

Q8NEV8
KRSSSEDAESLAPRS

LARP7

296

Q4G0J3
SSVKRTFPEDESSSR

FCAMR

436

Q8WWV6
RRTPDSTFSETFKEG

GRHL1

206

Q9NZI5
TRTIDDVPFKTSTDS

FNIP1

846

Q8TF40
SERTLARPFDETKSS

CMYA5

2791

Q8N3K9
RTTESPSRVFTEEAK

ATF7IP2

121

Q5U623
KSLTEISTDFDRSSP

CYLD

386

Q9NQC7
VFSTETDKPSAQDSR

SLC39A12

21

Q504Y0
TSETSFSLSKEAPRE

ISM1

56

B1AKI9
PENTRTFSFTKDDES

SERPINI1

196

Q99574
KSLFTRPSSRSLTEE

MINAR1

701

Q9UPX6
PTTESFEKSVREDAS

TSEN2

201

Q8NCE0
RSESDSSPDSKAKTR

SRRM2

1556

Q9UQ35
SSFSPDEERRTKVQD

PPP4R1

601

Q8TF05
SRVSGSFPEDSSKER

STX7

126

O15400
SSTPTTSTRSRDKDD

SMARCA4

1421

P51532
TSEPSRDSFVVSKAD

SHCBP1L

456

Q9BZQ2
EFTDSPESRKEAASS

PITX2

36

Q99697
DSFPKSESEDSVKRS

SCN3A

521

Q9NY46
SPSPKSERSERSERS

U2SURP

946

O15042
STKSSGSESDRSERP

APC

2421

P25054
KRSPSESSSESRSRS

CLASRP

301

Q8N2M8
SARSTRDDPSNKETA

ZNF516

736

Q92618
AKVARPTSSEVDRFS

ZBTB37

296

Q5TC79
QRDRDSIKSSSVSPS

TLE4

196

Q04727
PARSSSLKSSSERND

SORBS1

501

Q9BX66
RTVSEKFSPETASRR

ST7L

376

Q8TDW4
SVTDRRSFSKVPETL

REM2

196

Q8IYK8
SLSEKSPLSSETRFD

USP17L7

36

P0C7H9
SPAVSKESSRRSSFS

TFEC

326

O14948
KSARSSSFTSGEREP

WEE2

551

P0C1S8
REEAESTPSKSARDS

PLEKHG1

676

Q9ULL1
RSRKTATNDEESPLS

PPIP5K2

966

O43314
SARPEKRDSRVSTSS

ZC3H14

121

Q6PJT7
DSTSTQEKRRRSFPD

ZNF318

516

Q5VUA4
KESTRRQDTRSPTSA

TNS2

921

Q63HR2
ENTKTISDSTSRRPS

ZC3H13

11

Q5T200
APRTSKTDSTIRTEN

ZNF7

76

P17097
DTPEKDSFRARSTSL

TSC2

926

P49815
VRDVSAPSSETFRKE

ZBTB40

126

Q9NUA8
RRFEVPTSKSSNSED

RNF39

196

Q9H2S5
TPTEERRTSFSTSDV

MYO9B

1346

Q13459