Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	SAM domain binding	DGKH L3MBTL1	1.36e-04	3	135	2	GO:0032093
GeneOntologyMolecularFunction	chromatin binding	TCF4 TCF3 SFPQ RBMXL1 FOXN4 H1-7 NR1H3 FOXA2 TFAP2B BAHD1 SAFB L3MBTL1 SUPT5H TLE1 RBMX	1.45e-04	739	135	15	GO:0003682
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH17 DNAH9 DYNC1H1	2.29e-04	18	135	3	GO:0008569
GeneOntologyMolecularFunction	extracellular matrix structural constituent conferring tensile strength	COL4A4 COL4A6 COL11A2 COL5A3	2.62e-04	46	135	4	GO:0030020
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	HJV TRERF1 ONECUT2 BCL9L TCF4 TCF3 SFPQ RBMXL1 FOXN4 ZNF212 ETV4 POU3F1 CRTC1 NR1H3 SIX3 FOXA2 TFAP2B ZEB2 KMT2D MED19 SAFB SUPT5H ZMIZ2 RBMX TAF7	4.50e-06	1390	137	25	GO:0045944
GeneOntologyCellularComponent	complex of collagen trimers	COL4A4 COL4A6 COL11A2 COL5A3	9.41e-06	21	136	4	GO:0098644
GeneOntologyCellularComponent	beta-catenin-TCF complex	BCL9L TCF4 TLE1	7.34e-05	13	136	3	GO:1990907
GeneOntologyCellularComponent	supraspliceosomal complex	RBMXL1 RBMX	2.50e-04	4	136	2	GO:0044530
GeneOntologyCellularComponent	RNA polymerase II transcription regulator complex	BCL9L TCF4 TCF3 SFPQ NR1H3 MED19 TLE1 TAF7	4.15e-04	272	136	8	GO:0090575
GeneOntologyCellularComponent	transcription regulator complex	TRERF1 BCL9L TCF4 TCF3 SFPQ POU3F1 NR1H3 SIX3 FOXA2 MED19 TLE1 TAF7	5.28e-04	596	136	12	GO:0005667
GeneOntologyCellularComponent	chromatin	ONECUT2 TCF4 TCF3 SFPQ FOXN4 H1-7 ETV4 POU3F1 NR1H3 RHOXF1 SIX3 FOXA2 TFAP2B ZEB2 PPP1R10 TCF23 L3MBTL1 ZMIZ2 RBMX ZFHX2 TAF7	5.81e-04	1480	136	21	GO:0000785
GeneOntologyCellularComponent	collagen type IV trimer	COL4A4 COL4A6	6.20e-04	6	136	2	GO:0005587
GeneOntologyCellularComponent	basement membrane collagen trimer	COL4A4 COL4A6	1.15e-03	8	136	2	GO:0098651
GeneOntologyCellularComponent	network-forming collagen trimer	COL4A4 COL4A6	1.15e-03	8	136	2	GO:0098642
GeneOntologyCellularComponent	collagen network	COL4A4 COL4A6	1.15e-03	8	136	2	GO:0098645
GeneOntologyCellularComponent	nuclear protein-containing complex	TRERF1 BCL9L TCF4 TCF3 SFPQ KMT2B RBMXL1 NR1H3 BAHD1 SF1 KMT2D MED19 L3MBTL1 SUPT5H TLE1 RBMX TAF7 SRRM2 CSTF2T	1.50e-03	1377	136	19	GO:0140513
Domain	Spt5_C_dom	SUPT5H SRRM2	5.03e-05	2	133	2	IPR024945
Domain	CTD	SUPT5H SRRM2	5.03e-05	2	133	2	SM01104
Domain	RRM_1	SFPQ RBMXL1 MYEF2 SAFB RBM12 RBMX SAFB2 CSTF2T	1.23e-04	208	133	8	PF00076
Domain	RRM	SFPQ RBMXL1 MYEF2 SAFB RBM12 RBMX SAFB2 CSTF2T	1.65e-04	217	133	8	SM00360
Domain	RRM_dom	SFPQ RBMXL1 MYEF2 SAFB RBM12 RBMX SAFB2 CSTF2T	2.24e-04	227	133	8	IPR000504
Domain	RRM	SFPQ RBMXL1 MYEF2 SAFB RBM12 RBMX SAFB2 CSTF2T	2.45e-04	230	133	8	PS50102
Domain	FN3	OBSCN DSCAML1 GHR PTPRH ASTN2 ROBO3 IL2RB	3.64e-04	185	133	7	SM00060
Domain	-	SFPQ RBMXL1 MYEF2 SAFB RBM12 RBMX SAFB2 CSTF2T	3.64e-04	244	133	8	3.30.70.330
Domain	EPHD	KMT2B KMT2D RAI1	4.92e-04	22	133	3	PS51805
Domain	FYrich_C	KMT2B KMT2D	4.96e-04	5	133	2	IPR003889
Domain	FYrich_N	KMT2B KMT2D	4.96e-04	5	133	2	IPR003888
Domain	FYRC	KMT2B KMT2D	4.96e-04	5	133	2	SM00542
Domain	FYRN	KMT2B KMT2D	4.96e-04	5	133	2	SM00541
Domain	FYRN	KMT2B KMT2D	4.96e-04	5	133	2	PF05964
Domain	FYRC	KMT2B KMT2D	4.96e-04	5	133	2	PF05965
Domain	FYRC	KMT2B KMT2D	4.96e-04	5	133	2	PS51543
Domain	FYRN	KMT2B KMT2D	4.96e-04	5	133	2	PS51542
Domain	Nucleotide-bd_a/b_plait	SFPQ RBMXL1 MYEF2 SAFB RBM12 RBMX SAFB2 CSTF2T	5.28e-04	258	133	8	IPR012677
Domain	FN3	OBSCN DSCAML1 GHR PTPRH ASTN2 ROBO3 IL2RB	5.63e-04	199	133	7	PS50853
Domain	Homeodomain-like	TRERF1 ONECUT2 TCF4 TCF3 POU3F1 RHOXF1 SIX3 ZEB2 ZFHX2	6.28e-04	332	133	9	IPR009057
Domain	C4	COL4A4 COL4A6	7.41e-04	6	133	2	SM00111
Domain	Collagen_VI_NC	COL4A4 COL4A6	7.41e-04	6	133	2	IPR001442
Domain	NC1_IV	COL4A4 COL4A6	7.41e-04	6	133	2	PS51403
Domain	-	COL4A4 COL4A6	7.41e-04	6	133	2	2.170.240.10
Domain	C4	COL4A4 COL4A6	7.41e-04	6	133	2	PF01413
Domain	FN3_dom	OBSCN DSCAML1 GHR PTPRH ASTN2 ROBO3 IL2RB	7.52e-04	209	133	7	IPR003961
Domain	AT_hook	KMT2B FAM171B ZNF653	9.11e-04	27	133	3	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2B FAM171B ZNF653	9.11e-04	27	133	3	IPR017956
Domain	DHC_N1	DNAH9 DYNC1H1	1.37e-03	8	133	2	PF08385
Domain	RBM1CTR	RBMXL1 RBMX	1.37e-03	8	133	2	PF08081
Domain	RBM1CTR	RBMXL1 RBMX	1.37e-03	8	133	2	IPR012604
Domain	Dynein_heavy_dom-1	DNAH9 DYNC1H1	1.37e-03	8	133	2	IPR013594
Domain	IGv	OBSCN DSCAML1 BTNL2 CD276	2.02e-03	75	133	4	SM00406
Domain	Amino_oxidase	PYROXD2 PAOX	2.18e-03	10	133	2	IPR002937
Domain	Amino_oxidase	PYROXD2 PAOX	2.18e-03	10	133	2	PF01593
Domain	NC1_FIB	COL11A2 COL5A3	2.65e-03	11	133	2	PS51461
Domain	Fib_collagen_C	COL11A2 COL5A3	2.65e-03	11	133	2	PD002078
Domain	Fib_collagen_C	COL11A2 COL5A3	2.65e-03	11	133	2	IPR000885
Domain	COLFI	COL11A2 COL5A3	2.65e-03	11	133	2	PF01410
Domain	COLFI	COL11A2 COL5A3	2.65e-03	11	133	2	SM00038
Domain	Collagen	COL4A4 COL4A6 COL11A2 COL5A3	3.19e-03	85	133	4	IPR008160
Domain	Collagen	COL4A4 COL4A6 COL11A2 COL5A3	3.19e-03	85	133	4	PF01391
Domain	PHD	KMT2B DIDO1 KMT2D RAI1	3.76e-03	89	133	4	SM00249
Domain	Znf_FYVE_PHD	KMT2B DIDO1 KMT2D FGD1 MLPH	4.05e-03	147	133	5	IPR011011
Domain	Znf_PHD	KMT2B DIDO1 KMT2D RAI1	4.07e-03	91	133	4	IPR001965
Domain	Dynein_heavy_chain_D4_dom	DNAH9 DYNC1H1	4.33e-03	14	133	2	IPR024317
Domain	Dynein_HC_stalk	DNAH9 DYNC1H1	4.33e-03	14	133	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH9 DYNC1H1	4.33e-03	14	133	2	IPR013602
Domain	DHC_N2	DNAH9 DYNC1H1	4.33e-03	14	133	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH9 DYNC1H1	4.33e-03	14	133	2	IPR011704
Domain	MT	DNAH9 DYNC1H1	4.33e-03	14	133	2	PF12777
Domain	AAA_8	DNAH9 DYNC1H1	4.33e-03	14	133	2	PF12780
Domain	AAA_5	DNAH9 DYNC1H1	4.33e-03	14	133	2	PF07728
Domain	ZF_PHD_2	KMT2B DIDO1 KMT2D RAI1	4.75e-03	95	133	4	PS50016
Domain	ZF_PHD_1	KMT2B DIDO1 KMT2D RAI1	4.93e-03	96	133	4	PS01359
Domain	DHC_fam	DNAH9 DYNC1H1	4.97e-03	15	133	2	IPR026983
Domain	Dynein_heavy	DNAH9 DYNC1H1	4.97e-03	15	133	2	PF03028
Domain	Dynein_heavy_dom	DNAH9 DYNC1H1	4.97e-03	15	133	2	IPR004273
Domain	Post-SET_dom	KMT2B KMT2D	5.66e-03	16	133	2	IPR003616
Domain	PostSET	KMT2B KMT2D	5.66e-03	16	133	2	SM00508
Domain	POST_SET	KMT2B KMT2D	5.66e-03	16	133	2	PS50868
Domain	PH	ASAP3 OBSCN DGKH IRS1 PHLDB1 FGD1	6.00e-03	229	133	6	PF00169
Domain	fn3	OBSCN DSCAML1 GHR PTPRH ROBO3	6.09e-03	162	133	5	PF00041
Domain	HOMEOBOX_1	ONECUT2 POU3F1 RHOXF1 SIX3 ZEB2 ZFHX2	6.92e-03	236	133	6	PS00027
Domain	HOX	ONECUT2 POU3F1 RHOXF1 SIX3 ZEB2 ZFHX2	7.06e-03	237	133	6	SM00389
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	COL4A4 COL4A6 COL11A2 COL5A3 SDC3	2.07e-06	32	94	5	MM14924
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	COL4A4 COL4A6 COL11A2 COL5A3 SDC3	4.46e-05	59	94	5	M27218
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	DIDO1 TACC2 SF1 SAFB RBM12 KHDRBS1 SAFB2 TAF7 SRRM2	2.75e-09	130	138	9	35545047
Pubmed	Proteomic analysis of the cullin 4B interactome using proximity-dependent biotinylation in living cells.	SFPQ RBMXL1 SF1 SAFB KHDRBS1 RBMX SAFB2 SRRM2 CSTF2T	1.15e-08	153	138	9	28225217
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	BCL9L GBF1 DIDO1 CRTC1 FCHO1 GHR PHLDB1 SAFB KHDRBS1 RBMX SRRM2 DNAH9	2.46e-08	361	138	12	26167880
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TRERF1 TCF3 SFPQ KMT2B DIDO1 ZEB2 SF1 KMT2D SAFB RBM12 KHDRBS1 MTHFD1 ZMIZ2 RBMX SAFB2 SRRM2 DYNC1H1 CSTF2T RAI1	8.28e-08	1103	138	19	34189442
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RIN3 GBF1 KMT2B TSNARE1 COX6A1 OBSCN IRS1 BAHD1 GGT7 NHSL1 PHLDB1 KMT2D IGF2R MEGF8 ZMIZ2 DYNC1H1 WNK2 RAI1 CD276	8.52e-08	1105	138	19	35748872
Pubmed	A census of human transcription factors: function, expression and evolution.	TRERF1 ONECUT2 TCF4 TCF3 FOXN4 ETV4 POU3F1 NR1H3 RHOXF1 SIX3 FOXA2 TFAP2B ZEB2 TCF23 KMT2D ZFHX2 ZNF653	1.31e-07	908	138	17	19274049
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ONECUT2 TCF3 SFPQ KMT2B FNBP4 DIDO1 TRIM27 SF1 PPP1R10 ESYT2 KMT2D SAFB KHDRBS1 ZIC5 SUPT5H RBMX SAFB2 TAF7 SRRM2 RAI1	2.09e-07	1294	138	20	30804502
Pubmed	SAFB1, an RBMX-binding protein, is a newly identified regulator of hepatic SREBP-1c gene.	RBMXL1 SAFB RBMX	2.44e-07	4	138	3	19403048
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TRERF1 GBF1 KMT2B FNBP4 DIDO1 SF1 ESYT2 KMT2D SAFB RBMX SAFB2 SRRM2 MAP2K2 MN1 CSTF2T	4.92e-07	774	138	15	15302935
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	ONECUT2 SFPQ RBMXL1 BCKDK FNBP4 DIDO1 SF1 MYEF2 PPP1R10 SAFB KHDRBS1 SUPT5H RBMX SAFB2 SRRM2 DYNC1H1 CSTF2T	1.48e-06	1082	138	17	38697112
Pubmed	The STAR/GSG family protein rSLM-2 regulates the selection of alternative splice sites.	SAFB KHDRBS1 RBMX	2.11e-06	7	138	3	11118435
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	TCF4 TCF3 ZNF212 ETV4 NR1H3 RHOXF1 TRIM27 TFAP2B ZEB2 KHDRBS1 SUPT5H TLE1 RBMX TAF7 RAI1	2.31e-06	877	138	15	20211142
Pubmed	The LMO2 oncogene regulates DNA replication in hematopoietic cells.	TCF4 TCF3 KMT2B RAI1 CAPN15	3.54e-06	58	138	5	26764384
Pubmed	Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis.	GBF1 OBSCN TRIM27 SF1 ESYT2 SAFB2 MAP2K2	3.59e-06	159	138	7	31332168
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	KMT2B DIDO1 SRRM2 DNAH9 DYNC1H1 PDZD2	3.86e-06	104	138	6	9205841
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SFPQ DIDO1 SF1 MYEF2 PPP1R10 SAFB RBM12 KHDRBS1 SUPT5H RBMX SAFB2 SRRM2 DYNC1H1 CSTF2T	4.35e-06	807	138	14	22681889
Pubmed	Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.	SFPQ RBMXL1 MYEF2 SAFB KHDRBS1 RBMX	5.07e-06	109	138	6	29511296
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	TCF4 TCF3 FOXN4 DIDO1 POU3F1 NR1H3 TACC2 TFAP2B SF1 TCF23 SLC18A3 ZMIZ2 ZFHX2	5.39e-06	709	138	13	22988430
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TCF3 PCDHGB1 TSNARE1 OBSCN FNBP4 DGKH KLHL29 ESYT2 PHLDB1 TVP23C ZFHX2 SDC3 ASTN2 ALDH3B2 MAP2K2 MLPH WNK2 RAI1 PDZD2	7.14e-06	1489	138	19	28611215
Pubmed	Identification of Signaling Pathways for Early Embryonic Lethality and Developmental Retardation in Sephs1-/- Mice.	SIX3 FOXA2 SEPHS1	7.19e-06	10	138	3	34769078
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	BCL9L TCF3 SFPQ SF1 KHDRBS1 RBMX RAI1	8.11e-06	180	138	7	35198878
Pubmed	Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1.	FOXN4 ETV4 FOXA2 SLC18A3	8.88e-06	33	138	4	18662545
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBAP2 ZNF212 FNBP4 DIDO1 CRTC1 BAHD1 MYEF2 RBM12 SDC3 WNK2 RAI1	9.20e-06	529	138	11	14621295
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	DIDO1 SF1 MYEF2 PPP1R10 KMT2D KHDRBS1 SAFB2 TAF7 SRRM2	9.53e-06	341	138	9	32971831
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	SFPQ RBMXL1 SF1 MYEF2 SAFB RBM12 KHDRBS1 RBMX CSTF2T	1.10e-05	347	138	9	16033648
Pubmed	The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1.	FNBP4 SF1 KHDRBS1	1.31e-05	12	138	3	11604498
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	FNBP4 BAHD1 DSCAML1 RBM12 HACE1 PDZD2	1.39e-05	130	138	6	12421765
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	SFPQ ZNF212 BCKDK TACC2 TRIM27 PHLDB1 L3MBTL1 KHDRBS1 MEGF8 SAFB2 ADAMTSL2	1.56e-05	560	138	11	21653829
Pubmed	Identification and characterisation of a novel GHR defect disrupting the polypyrimidine tract and resulting in GH insensitivity.	SFPQ GHR	1.56e-05	2	138	2	19812236
Pubmed	Scaffold attachment factors SAFB1 and SAFB2: Innocent bystanders or critical players in breast tumorigenesis?	SAFB SAFB2	1.56e-05	2	138	2	14587024
Pubmed	Common variation at 2q22.3 (ZEB2) influences the risk of renal cancer.	ZEB2 PDZD2	1.56e-05	2	138	2	23184150
Pubmed	Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4).	KMT2B KMT2D	1.56e-05	2	138	2	35640156
Pubmed	Allogeneic stem cell transplantation mitigates the adverse prognostic impact of high diagnostic BAALC and MN1 expression in AML.	MN1 BAALC	1.56e-05	2	138	2	32862286
Pubmed	GHR and IGF2R genes may contribute to normal variations in craniofacial dimensions: Insights from an admixed population.	GHR IGF2R	1.56e-05	2	138	2	33008707
Pubmed	Scaffold attachment factor B (SAFB)1 and SAFB2 cooperatively inhibit the intranuclear mobility and function of ERα.	SAFB SAFB2	1.56e-05	2	138	2	22566185
Pubmed	SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells.	SAFB SAFB2	1.56e-05	2	138	2	19901029
Pubmed	Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif.	TCF4 TCF3	1.56e-05	2	138	2	2105528
Pubmed	Transcription factor AP-2beta: a negative regulator of IRS-1 gene expression.	IRS1 TFAP2B	1.56e-05	2	138	2	20097161
Pubmed	No germline mutations in supposed tumour suppressor genes SAFB1 and SAFB2 in familial breast cancer with linkage to 19p.	SAFB SAFB2	1.56e-05	2	138	2	19077293
Pubmed	Low SAFB levels are associated with worse outcome in breast cancer patients.	SAFB SAFB2	1.56e-05	2	138	2	19137425
Pubmed	Comparison of methylation episignatures in KMT2B- and KMT2D-related human disorders.	KMT2B KMT2D	1.56e-05	2	138	2	35506254
Pubmed	FOXA2 attenuates the epithelial to mesenchymal transition by regulating the transcription of E-cadherin and ZEB2 in human breast cancer.	FOXA2 ZEB2	1.56e-05	2	138	2	25779673
Pubmed	Prognostic significance of combined BAALC and MN1 gene expression level in acute myeloid leukemia with normal karyotype.	MN1 BAALC	1.56e-05	2	138	2	33242229
Pubmed	Unravelling the RNA-Binding Properties of SAFB Proteins in Breast Cancer Cells.	SAFB SAFB2	1.56e-05	2	138	2	26273616
Pubmed	Control of RNA Pol II Speed by PNUTS-PP1 and Spt5 Dephosphorylation Facilitates Termination by a "Sitting Duck Torpedo" Mechanism.	PPP1R10 SUPT5H	1.56e-05	2	138	2	31677974
Pubmed	Scaffold attachment factor B2 (SAFB2)-null mice reveal non-redundant functions of SAFB2 compared with its paralog, SAFB1.	SAFB SAFB2	1.56e-05	2	138	2	26092125
Pubmed	Transcriptional network orchestrating regional patterning of cortical progenitors.	TCF4 POU3F1 ZIC5 TLE1	1.75e-05	39	138	4	34921112
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	TRERF1 ONECUT2 TCF4 ZNF212 ETV4 DIDO1 POU3F1 NR1H3 SF1 PPP1R10 ZIC5 ZMIZ2 ZNF653	2.14e-05	808	138	13	20412781
Pubmed	Selection system for genes encoding nuclear-targeted proteins.	ZEB2 RBM12 ZMIZ2	2.15e-05	14	138	3	9853615
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	COL4A4 KMT2B OBSCN HACE1 IL2RB MLPH WNK2	2.48e-05	214	138	7	22199357
Pubmed	Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron development.	ONECUT2 ETV4 POU3F1	3.30e-05	16	138	3	19800948
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	TCF4 TCF3 SFPQ SF1 RBM12 ZMIZ2	3.37e-05	152	138	6	38360978
Pubmed	TCF4 promotes colorectal cancer drug resistance and stemness via regulating ZEB1/ZEB2 expression.	TCF4 ZEB2	4.68e-05	3	138	2	31933004
Pubmed	The class I bHLH factors E2-2A and E2-2B regulate EMT.	TCF4 TCF3	4.68e-05	3	138	2	19295128
Pubmed	RBMX is a novel hepatic transcriptional regulator of SREBP-1c gene response to high-fructose diet.	RBMXL1 RBMX	4.68e-05	3	138	2	17188681
Pubmed	Novel Circular RNA CircUBAP2 Drives Tumor Progression by Regulating the miR-143/TFAP2B Axis in Prostate Cancer.	UBAP2 TFAP2B	4.68e-05	3	138	2	37962045
Pubmed	Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression.	FOXA2 G6PC2	4.68e-05	3	138	2	18753309
Pubmed	Pioneer factor Foxa2 enables ligand-dependent activation of type II nuclear receptors FXR and LXRα.	NR1H3 FOXA2	4.68e-05	3	138	2	34246806
Pubmed	RBMY evolved on the Y chromosome from a ubiquitously transcribed X-Y identical gene.	RBMXL1 RBMX	4.68e-05	3	138	2	10391207
Pubmed	Sam68 interacts with IRS1.	IRS1 KHDRBS1	4.68e-05	3	138	2	22005517
Pubmed	Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor, p62, and GTPase-activating protein.	IRS1 KHDRBS1	4.68e-05	3	138	2	8175658
Pubmed	E2-2 regulates the expansion of pro-B cells and follicular versus marginal zone decisions.	TCF4 TCF3	4.68e-05	3	138	2	17082585
Pubmed	A role for E2-2 at the DN3 stage of early thymopoiesis.	TCF4 TCF3	4.68e-05	3	138	2	18384878
Pubmed	Forebrain deletion of the vesicular acetylcholine transporter results in deficits in executive function, metabolic, and RNA splicing abnormalities in the prefrontal cortex.	SIX3 SLC18A3	4.68e-05	3	138	2	24027290
Pubmed	The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2.	SAFB SAFB2	4.68e-05	3	138	2	19674106
Pubmed	Transcriptional control of CBX5 by the RNA binding proteins RBMX and RBMXL1 maintains chromatin state in myeloid leukemia.	RBMXL1 RBMX	4.68e-05	3	138	2	34458856
Pubmed	The helix-loop-helix gene E2A is required for B cell formation.	TCF4 TCF3	4.68e-05	3	138	2	8001124
Pubmed	Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis.	TCF4 TCF3	4.68e-05	3	138	2	30593567
Pubmed	Histone methyltransferase MLL4 controls myofiber identity and muscle performance through MEF2 interaction.	KMT2B KMT2D	4.68e-05	3	138	2	32544095
Pubmed	BTNL2, a butyrophilin-like molecule that functions to inhibit T cell activation.	BTNL2 CD276	4.68e-05	3	138	2	16751379
Pubmed	iCLIP identifies novel roles for SAFB1 in regulating RNA processing and neuronal function.	SAFB ASTN2	4.68e-05	3	138	2	26694817
Pubmed	The histone methyltransferase KMT2B is required for RNA polymerase II association and protection from DNA methylation at the MagohB CpG island promoter.	KMT2B KMT2D	4.68e-05	3	138	2	23358417
Pubmed	TRIM27 acts as an oncogene and regulates cell proliferation and metastasis in non-small cell lung cancer through SIX3-β-catenin signaling.	SIX3 TRIM27	4.68e-05	3	138	2	33264103
Pubmed	Whole-Retina Reduced Electrophysiological Activity in Mice Bearing Retina-Specific Deletion of Vesicular Acetylcholine Transporter.	SIX3 SLC18A3	4.68e-05	3	138	2	26226617
Pubmed	Murine helix-loop-helix transcriptional activator proteins binding to the E-box motif of the Akv murine leukemia virus enhancer identified by cDNA cloning.	TCF4 TCF3	4.68e-05	3	138	2	1321336
Pubmed	B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.	TCF4 TCF3	4.68e-05	3	138	2	8649400
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	BCL9L SFPQ UBAP2 BCKDK TACC2 FAM171B SNAP47 MYEF2 GGT7 NHSL1 ESYT2 SAFB MTHFD1 WNK2 PHACTR1	4.96e-05	1139	138	15	36417873
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	SFPQ FNBP4 SAFB SUPT5H RBMX SRRM2	4.98e-05	163	138	6	22113938
Pubmed	Human transcription factor protein interaction networks.	TRERF1 BCL9L TCF4 TCF3 UBAP2 KMT2B COX6A1 ETV4 DIDO1 ZEB2 KMT2D RBM12 KHDRBS1 TLE1 ZMIZ2 SRRM2 DYNC1H1	5.41e-05	1429	138	17	35140242
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	CRTC1 PHLDB1 L3MBTL1 ASTN2 CSTF2T	5.59e-05	102	138	5	9734811
Pubmed	Molecular functions of the TLE tetramerization domain in Wnt target gene repression.	TCF4 TCF3 TLE1	5.65e-05	19	138	3	24596249
Pubmed	A crucial role for Arf6 in the response of commissural axons to Slit.	GBF1 FOXA2 ROBO3	5.65e-05	19	138	3	30674481
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	SFPQ SF1 MYEF2 PPP1R10 PHLDB1 SAFB IGF2R KHDRBS1 MTHFD1 SUPT5H RBMX SAFB2 SRRM2 DYNC1H1	6.03e-05	1024	138	14	24711643
Pubmed	Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.	SFPQ KMT2D SAFB KHDRBS1 RBMX SRRM2	6.30e-05	170	138	6	16159877
Pubmed	Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians.	SIX3 FOXA2 G6PC2	6.63e-05	20	138	3	25187374
Pubmed	Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals.	FOXN4 TFAP2B ZEB2	7.71e-05	21	138	3	27385012
Pubmed	Interaction network of human early embryonic transcription factors.	TRERF1 BCL9L KMT2B ZEB2 KMT2D TLE1 ZMIZ2 RAI1	8.45e-05	351	138	8	38297188
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	ONECUT2 SFPQ GBF1 UBAP2 COX6A1 IRS1 FOXA2 SF1 PPP1R10 ESYT2 SAFB IGF2R SAFB2 SRRM2 CD276	9.13e-05	1203	138	15	29180619
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	BCL9L SFPQ FOXA2 MYEF2 KMT2D RBM12 TLE1 RBMX RAI1	9.28e-05	457	138	9	32344865
Pubmed	Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.	KMT2B KMT2D	9.33e-05	4	138	2	19221051
Pubmed	Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains.	TCF4 TCF3	9.33e-05	4	138	2	11802795
Pubmed	Molecular functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development.	TCF4 TCF3	9.33e-05	4	138	2	27261530
Pubmed	SAFB1 interacts with and suppresses the transcriptional activity of p53.	SAFB SAFB2	9.33e-05	4	138	2	21130767
Pubmed	MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC.	FOXA2 ZEB2	9.33e-05	4	138	2	37566546
Pubmed	Epigenetic deregulation of TCF21 inhibits metastasis suppressor KISS1 in metastatic melanoma.	TCF4 TCF3	9.33e-05	4	138	2	21771727
Pubmed	STAR, a gene family involved in signal transduction and activation of RNA.	SF1 KHDRBS1	9.33e-05	4	138	2	9433137
Pubmed	MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing.	KMT2B KMT2D	9.33e-05	4	138	2	20808952
Pubmed	Mutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in mice.	KMT2B KMT2D	9.33e-05	4	138	2	23826075
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2B KMT2D	9.33e-05	4	138	2	23129768
Pubmed	Elimination of the vesicular acetylcholine transporter in the forebrain causes hyperactivity and deficits in spatial memory and long-term potentiation.	SIX3 SLC18A3	9.33e-05	4	138	2	23045697
Interaction	CAPN13 interactions	DIDO1 SF1 PPP1R10 SAFB SAFB2	1.40e-07	19	136	5	int:CAPN13
Interaction	PIN1 interactions	DDAH2 TCF4 SFPQ COL11A2 KMT2B DIDO1 TRIM27 SF1 SUPT5H TLE1 ZMIZ2 SRRM2 RAI1	2.02e-06	383	136	13	int:PIN1
GeneFamily	RNA binding motif containing	SFPQ RBMXL1 MYEF2 SAFB RBM12 RBMX SAFB2 CSTF2T	1.10e-05	213	90	8	725
GeneFamily	Collagens	COL4A4 COL4A6 COL11A2 COL5A3	7.98e-05	46	90	4	490
GeneFamily	Fibronectin type III domain containing	OBSCN DSCAML1 GHR PTPRH ASTN2 ROBO3	1.47e-04	160	90	6	555
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZEB2 ZFHX2	2.47e-03	15	90	2	529
GeneFamily	Dyneins, axonemal	DNAH17 DNAH9	3.17e-03	17	90	2	536
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ASAP3 DGKH IRS1 PHLDB1 FGD1	3.67e-03	206	90	5	682
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRERF1 HGD MSANTD1 PAOX NHSL1 TLE1 PTRH1	9.98e-07	169	138	7	f086b50791e1c93e253eb5e8d6c4bf617b1416c3
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	TRERF1 IRS1 IGFLR1 TLE1 DNAH9 ADAMTSL2 TBCEL	1.04e-06	170	138	7	fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ONECUT2 TCF4 UBAP2 PCDHGB1 DSCAML1 NYAP1 WNK2	2.10e-06	189	138	7	8e6b6025f5554672e26a5d19fe365acb4333789c
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|Liver / Manually curated celltypes from each tissue	PYROXD2 CRTC1 HACE1 RAI1 TBCEL PDZD2	8.64e-06	154	138	6	c6308074468235c88ef4ea43ab155d9f86cbf261
ToppCell	COVID-19_Severe-NK_CD56bright\|COVID-19_Severe / Disease condition and Cell class	TCF4 RIN3 PYROXD2 NR1H3 TLE1 IL2RB	1.57e-05	171	138	6	5810f790012a0750ca3378595514f66a99f123be
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A6 GGN ETV4 ZEB2 SDC3 PHACTR1	1.62e-05	172	138	6	1f335ccb92b22d0412954e8fc3af212f96410b67
ToppCell	droplet-Liver-nan-3m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A6 GGN ETV4 ZEB2 SDC3 PHACTR1	1.62e-05	172	138	6	bb96c896d125e10b71e94e2bdad243899045af5c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 CYP27C1 ETV4 DGKH TFAP2B ASTN2	2.16e-05	181	138	6	22363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCell	facs-Lung-Endomucin-24m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GGN NR1H3 PAOX PTRH1 MLPH PDZD2	2.23e-05	182	138	6	be9c312a44868d4ee266a64d066feb8c5bce5687
ToppCell	B_cell_maturation-immature_B_cell\|World / Lineage and Cell class	TCF4 TCF3 ZEB2 TLE1 TMEM38A PHACTR1	2.23e-05	182	138	6	2c7c51ebc4125d8a33454ffee0b143579ce5e451
ToppCell	facs-Lung-Endomucin-24m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GGN NR1H3 PAOX PTRH1 MLPH PDZD2	2.23e-05	182	138	6	74dbb706bcaa0f8c922bf3b0424bce5bb27167fa
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CA9 COL4A6 TACC2 ESYT2 MN1 ADAMTSL2	2.30e-05	183	138	6	a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCell	mild-B_cell\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	COL4A4 TCF4 PAOX L3MBTL1 TMEM38A PHACTR1	2.30e-05	183	138	6	175aaf8fbbff52eab87d78a49d5ab02cd489c438
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM171B GGT7 KLHL29 ASTN2 MLPH ADAMTSL2	2.44e-05	185	138	6	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM171B GGT7 KLHL29 ASTN2 MLPH ADAMTSL2	2.44e-05	185	138	6	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM171B GGT7 KLHL29 ASTN2 MLPH ADAMTSL2	2.44e-05	185	138	6	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	LV-07._Pericyte\|LV / Chamber and Cluster_Paper	TCF4 COL5A3 DSCAML1 ZEB2 TLE1 PDZD2	2.44e-05	185	138	6	acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CPNE2 GBF1 IGFLR1 IGF2R SDC3 IL2RB	2.59e-05	187	138	6	4527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	OBSCN COL5A3 GHR PHLDB1 TLE1 WNK2	2.59e-05	187	138	6	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	SFPQ DGKH ZEB2 PPP1R10 IGF2R DYNC1H1	2.67e-05	188	138	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 ETV4 DGKH TFAP2B ASTN2 PHACTR1	2.75e-05	189	138	6	e059be2965cca70ff5576df055d0af1775b76e00
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 COL4A4 ZEB2 GHR KLHL29 ADAMTSL2	2.92e-05	191	138	6	a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 COL4A4 ZEB2 GHR KLHL29 ADAMTSL2	2.92e-05	191	138	6	8f6d592edc32fdb901af30501d4360512334e8c2
ToppCell	human_hepatoblastoma-Endothelial_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	TCF4 DGKH ZEB2 PDZD2 PHACTR1 BAALC	3.01e-05	192	138	6	e09f609fed033a25baacaf4a07bbbae1076da366
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CYP27C1 ASAP3 COL5A3 TACC2 PIANP EFNB3	3.10e-05	193	138	6	3d85c28f6ebdcb15e875ad01d52d6c138fbf8525
ToppCell	severe-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	COL4A4 HGD TCF3 TNFRSF10A L3MBTL1 TLE1	3.19e-05	194	138	6	2fee6083fb56b16d1f04fd0b92ec622fd26ba3fa
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	OBSCN TACC2 ASTN2 WNK2 PDZD2 PHACTR1	3.19e-05	194	138	6	c3535f7cc0076653c72db582047cff053c322397
ToppCell	mild-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	COL4A4 TCF4 PAOX L3MBTL1 TMEM38A PHACTR1	3.28e-05	195	138	6	1e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THEM5 TACC2 FAM171B TFAP2B KLHL29 MN1	3.38e-05	196	138	6	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	10x3'2.3-week_17-19\|World / cell types per 3 fetal stages;per 3',per 5'	TCF3 SFPQ PPP1R10 TAF7 SRRM2 PHACTR1	3.47e-05	197	138	6	f5cfad0b42d0f817e22cc78b9bfb2b4b7e4330ed
ToppCell	normal_Pleural_Fluid-T/NK_cells-NK\|T/NK_cells / Location, Cell class and cell subclass	TCF4 RIN3 ZEB2 TLE1 IL2RB BAALC	3.47e-05	197	138	6	52e6b772f8c3a623b1b0c28119918fb9935803e1
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A6 TCF4 OBSCN POU3F1 DGKH GHR	3.47e-05	197	138	6	1e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TCF4 TCF3 SFPQ ZEB2 SF1 TAF7	3.57e-05	198	138	6	5f465cf5c7493e32d9afe9e9d05757d0a95acc33
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TCF4 TCF3 SFPQ ZEB2 SF1 TAF7	3.57e-05	198	138	6	77ce3fe1ab161c0faf8987e73a64ab61294b9255
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A4 TACC2 NHSL1 MLPH PDZD2 PHACTR1	3.67e-05	199	138	6	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A4 TACC2 NHSL1 MLPH PDZD2 PHACTR1	3.67e-05	199	138	6	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A4 TACC2 NHSL1 MLPH PDZD2 PHACTR1	3.67e-05	199	138	6	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ASAP3 COL5A3 IRS1 TMEM38A NYAP1 CAPN15	3.67e-05	199	138	6	a13f4b8a039304e685464cc8879659824cad5a3e
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A4 TACC2 NHSL1 MLPH PDZD2 PHACTR1	3.67e-05	199	138	6	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	TCF4 OBSCN COL5A3 DGKH PHLDB1 PDZD2	3.78e-05	200	138	6	0c648941447c738caf62f2d71e296d6cca492c8b
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ASAP3 ETV4 CRTC1 TMEM38A NYAP1 PDZD2	3.78e-05	200	138	6	36de49593cf6ff1c9229fcceb150c1d68658a360
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TCF4 OBSCN COL5A3 DGKH PHLDB1 PDZD2	3.78e-05	200	138	6	522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Mesoderm\|5w / Sample Type, Dataset, Time_group, and Cell type.	CA9 BCL9L TSNARE1 TMEM253 DGKH MSANTD1	3.78e-05	200	138	6	0927061536a664b4f7feb9e5b0a8c11ca0d5955c
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	TCF4 OBSCN COL5A3 DGKH PHLDB1 PDZD2	3.78e-05	200	138	6	94f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCell	COVID-19-COVID-19_Mild\|COVID-19 / Disease, condition lineage and cell class	SFPQ FNBP4 TYMP ZEB2 SF1 SRRM2	3.78e-05	200	138	6	62c25042086f1afd1102e0720e933c2e476468fd
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-CPNs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	DDAH2 TCF4 POU3F1 ZEB2 NHSL1 MN1	3.78e-05	200	138	6	71cbefbef4ae5bbb5f6e419914f4b3b3b5a5f9e3
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ASAP3 ETV4 PHLDB1 TMEM38A NYAP1 PDZD2	3.78e-05	200	138	6	4c3c11dd5e71ebc3d62264eeaeb71a850b149779
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Sla\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	POU3F1 ZNF831 ROBO3 ALDH3B2 ADAMTSL2	5.71e-05	132	138	5	ddebc0b233fdbb73ceb70187945bbed8fd273f2a
ToppCell	droplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l33\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL5A3 IGF2R MEGF8 TMEM38A ZNF653	6.58e-05	136	138	5	a43b3db1754c619d328a26a2ba6af4756629a723
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PCDHGB1 TFAP2B PTPRH ALDH3B2	6.64e-05	70	138	4	e1ac00f4a519b6ada89f591e549874bd3eed0ca1
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PCDHGB1 TFAP2B PTPRH ALDH3B2	6.64e-05	70	138	4	27e12c0f43a996bcbed285c5ee668bef5a786d80
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PCDHGB1 TFAP2B PTPRH ALDH3B2	6.64e-05	70	138	4	b6815131e87e81c10e65bc398a84dab5a74b32ac
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_stem_cell\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CD300LF DIDO1 POU3F1 SIX3 MN1	6.82e-05	137	138	5	ed81624b9167255ce88dcf6ad7f1636376ea0525
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_stem_cell-Mesenchymal_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CD300LF DIDO1 POU3F1 SIX3 MN1	6.82e-05	137	138	5	47859aa25f32367461c1ec75ed9060bee430c6b7
ToppCell	COVID-19-kidney-EC(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	TCF4 CYBRD1 ZNF831 ZEB2 BTNL2	7.81e-05	141	138	5	fd08f4add62af55d2114afcf681c3c6b995e8e57
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A4 COL4A6 PCDHGB1 FOXA2 PPP1R3F	9.21e-05	146	138	5	669001b772b6d6109a09727619ed5829122b48db
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	DGKH ZEB2 SF1 KMT2D DYNC1H1	9.51e-05	147	138	5	94998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	COL4A4 TCF4 GGT7 ZNF653 ADAMTSL2	1.01e-04	149	138	5	14d2e8cab97108d8fa94e540c1957b73ed32dc73
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	COL4A4 TCF4 GGT7 ZNF653 ADAMTSL2	1.01e-04	149	138	5	54c9c6282f5f5de43dfaf2972fab3e3dcf9838a3
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CA9 TMEM253 LCT DSCAML1 BTNL2	1.01e-04	149	138	5	7726957b1de638c3bfc659381d15eab626bb179b
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Chrm2_(Cerebellum_basket_cells_4)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SIX3 LCT MSANTD1 L3MBTL1	1.12e-04	80	138	4	54f520cca126810510479fbeade2e3f66fb5dd1b
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Chrm2_(Cerebellum_basket_cells_4)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SIX3 LCT MSANTD1 L3MBTL1	1.12e-04	80	138	4	ce38ea123853a1e1082a033fb779b63ea440661d
ToppCell	COVID-19_Severe-NK_CD56bright\|COVID-19_Severe / disease group, cell group and cell class	PYROXD2 NR1H3 RHOXF1 ZNF831 IL2RB	1.37e-04	159	138	5	9e2067f0d76769717f7048dab505fadd36bbb83e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 COL4A4 COL5A3 ZEB2 BTNL2	1.37e-04	159	138	5	e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 COL4A4 COL5A3 ZEB2 BTNL2	1.37e-04	159	138	5	2607b562903228274fbd96168ba826782fab0b53
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM253 OBSCN EFNB3 ROBO3 BAALC	1.41e-04	160	138	5	237430af14830b38e58da8a4224036e5c6b71c5b
ToppCell	PND01-03-samps-Myeloid-Macrophage-CD163+_Macrophage\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	CA9 ZNF831 BAHD1 PAOX EFNB3	1.41e-04	160	138	5	4480a7d6bd48d06b4e5196faac868f31ab7ed3ad
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	COL4A4 DDAH2 TCF4 TCF3 TLE1	1.46e-04	161	138	5	63f0b97c741b610c450f65fa5764d712bfe09ce8
ToppCell	PND01-03-samps\|World / Age Group, Lineage, Cell class and subclass	COL4A4 ONECUT2 SFPQ DGKH TFAP2B	1.46e-04	161	138	5	1973b112d8d67aacc02751797d0148e7b53bfa66
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TSNARE1 IRS1 TFAP2B DSCAML1 PHACTR1	1.54e-04	163	138	5	cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCell	BAL-Mild-cDC_0\|Mild / Compartment, Disease Groups and Clusters	CD300LF GGN PHLDB1 SDC3 FAM216A	1.54e-04	163	138	5	7047d3ba847930f42a6d5f71e18d49f3071c6409
ToppCell	mild_COVID-19_(asymptomatic)-B_cell\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	COL4A4 HGD TSNARE1 GGT7 L3MBTL1	1.59e-04	164	138	5	e4d43af7eb04d55328791b554bdf3a7ce6818027
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR1H3 ZEB2 PTPRH SDC3 CD276	1.68e-04	166	138	5	91eeb48680dd07ae4115afacdc0a8f6fa18885e5
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-cDC2\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GGN ZEB2 DNAH17 TVP23C PHACTR1	1.73e-04	167	138	5	1bd0aa7a3c8649f342bb856cf861c4c5984ad889
ToppCell	COVID-19_Moderate-Treg\|COVID-19_Moderate / disease group, cell group and cell class	CPNE2 DGKH RHOXF1 ZNF831 PPP1R3F	1.73e-04	167	138	5	4ddb21421cbe72c06b61dd3a5eb1337e59de42e5
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	ONECUT2 DDAH2 ETV4 MN1 BAALC	1.73e-04	167	138	5	cb396f3edb9e8fdc316091e8e193dbba50e0be0c
ToppCell	droplet-Lung-LUNG-30m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE2 GGN DSCAML1 CLCN6 ZMIZ2	1.78e-04	168	138	5	0e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	RIN3 ZEB2 TLE1 IL2RB BAALC	1.78e-04	168	138	5	b4bb03efb601a61465260f93896c56861c588bef
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	RIN3 ZEB2 TLE1 IL2RB BAALC	1.78e-04	168	138	5	240ea32b64d86f9216785010d6b237d9adf052c9
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 NR1H3 TCF23 MN1 PDZD2	1.83e-04	169	138	5	2d23b4cee060f8adddc430c1c10d4e25205b4af6
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 NR1H3 TCF23 MN1 PDZD2	1.83e-04	169	138	5	ecaf08e8e0b54d1c97a02bc1f65409fd43d68227
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	RIN3 ZEB2 TLE1 IL2RB BAALC	1.83e-04	169	138	5	e7470a5b060881b2a8ce2ab04b0788396aa13889
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 NR1H3 TCF23 MN1 PDZD2	1.83e-04	169	138	5	ad6af6609acf158cb79e45ee7ca9af332be3c40c
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDAH2 CD300LF DSCAML1 MN1 WNK2	1.88e-04	170	138	5	c638dfde9ce30190abbe0caea1c3eb874af09857
ToppCell	facs-Brain_Myeloid-Striatum-24m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV4 POU3F1 SIX3 TFAP2B IL2RB	1.88e-04	170	138	5	626c12b9a51218f72ee32afb5fd5d4b075025d75
ToppCell	facs-Brain_Myeloid-Striatum-24m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV4 POU3F1 SIX3 TFAP2B IL2RB	1.88e-04	170	138	5	31daac8696ae8c021c0302d3b30dd8194054b3e7
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	COL4A4 TCF3 PYROXD2 IGFLR1 SNAP47	1.88e-04	170	138	5	32917888c3f1d54302675c1d4de1fd3b7c79af5f
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD300LF ZNF831 DSCAML1 SLC18A3 MN1	1.88e-04	170	138	5	17bd7fd25a2657cb536ad47e294332920f759e95
ToppCell	facs-Brain_Myeloid-Striatum-24m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV4 POU3F1 SIX3 TFAP2B IL2RB	1.88e-04	170	138	5	ca88dc0b7a6960facb7c4d3c0f4795431a0a43d2
ToppCell	facs-Brain_Myeloid-Striatum-24m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV4 POU3F1 SIX3 TFAP2B IL2RB	1.88e-04	170	138	5	b6882665a27c78a63f3b4a2a8806c8438a98e407
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	RIN3 PYROXD2 TLE1 IL2RB BAALC	1.98e-04	172	138	5	e3a8891694343b6b01e80a200ae338d24797e417
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CPNE2 CYBRD1 DGKH BAHD1 PPP1R3F	2.04e-04	173	138	5	efb8072475000888efe088d00e870c56ffad4172
ToppCell	facs-Trachea-nan-24m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A2 PRSS16 ETV4 FOXA2 EFNB3	2.04e-04	173	138	5	2226505610af1becc253d0a5550627144ef0ed6b
ToppCell	Mild/Remission-B_naive-8\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TCF4 ZEB2 SF1 TLE1 PHACTR1	2.04e-04	173	138	5	694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCell	COVID-19_Moderate-NK_CD56bright\|COVID-19_Moderate / disease group, cell group and cell class	PYROXD2 SIX3 TLE1 IL2RB BAALC	2.04e-04	173	138	5	a07dcb1e555caaa2235aec219334fcbf2d07f10c
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CPNE2 CYBRD1 DGKH BAHD1 PPP1R3F	2.09e-04	174	138	5	58300d64d3b6fd9ba1b6c87ea83b2777eb6be2f4
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDAH2 CD300LF DSCAML1 PPP1R3F ERICH6	2.15e-04	175	138	5	f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	UBAP2 ASAP3 PPP1R10 SDC3 TAF7	2.15e-04	175	138	5	e99e145a152f534b75267ec492a252a0b814b4f8
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|normal_Lymph_Node / Location, Cell class and cell subclass	TCF4 ZEB2 ZMIZ2 HACE1 RAI1	2.20e-04	176	138	5	476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CPNE2 STK35 ESYT2 HACE1 ROBO3	2.26e-04	177	138	5	8dfadd9852e0c256363471a7cfe6af120c8c51e0
Drug	Bacampicillin hydrochloride [37661-08-8]; Down 200; 8uM; PC3; HT_HG-U133A	CA9 TCF3 SFPQ KMT2B PHLDB1 ZMIZ2 SAFB2 SRRM2 CSTF2T	3.07e-06	198	136	9	4592_DN
Drug	Iohexol [66108-95-0]; Up 200; 4.8uM; MCF7; HT_HG-U133A	TCF3 GBF1 BAHD1 PHLDB1 CLCN6 ZMIZ2 ROBO3 SRRM2 CAPN15	3.33e-06	200	136	9	3322_UP
Drug	Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A	CRTC1 BAHD1 EFNB3 ZMIZ2 DNAH17 SDC3 ROBO3 CSTF2T	2.15e-05	193	136	8	3973_DN
Drug	Benzbromarone [3562-84-3]; Down 200; 9.4uM; PC3; HT_HG-U133A	TCF4 RIN3 CYBRD1 SIX3 PTPRH ZMIZ2 SRRM2 TBCEL	2.40e-05	196	136	8	6669_DN
Drug	Allantoin [97-59-6]; Up 200; 25.2uM; PC3; HT_HG-U133A	CA9 ONECUT2 PHLDB1 EFNB3 PTPRH ZMIZ2 ZFHX2 TBCEL	2.40e-05	196	136	8	5052_UP
Drug	Pizotifen malate [5189-11-7]; Down 200; 9.4uM; PC3; HT_HG-U133A	CRTC1 FOXA2 BAHD1 EFNB3 FGD1 ASTN2 CSTF2T CAPN15	2.40e-05	196	136	8	5072_DN
Drug	Pergolide mesylate [66104-23-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A	KMT2B ZNF212 SF1 PHLDB1 RBM12 SAFB2 CSTF2T CAPN15	2.49e-05	197	136	8	7434_DN
Drug	Mianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A	COL4A6 GBF1 ASAP3 IGFLR1 RBM12 FGD1 SDC3 SRRM2	2.58e-05	198	136	8	2068_DN
Drug	Trazodone hydrochloride [25332-39-2]; Up 200; 9.8uM; HL60; HT_HG-U133A	RIN3 CRTC1 TYMP KHDRBS1 ZFHX2 ASTN2 G6PC2 TBCEL	2.58e-05	198	136	8	2379_UP
Drug	F0447-0125; Down 200; 10uM; PC3; HT_HG-U133A	RIN3 ASAP3 CRTC1 FOXA2 MYEF2 PHLDB1 SDC3 MN1	2.68e-05	199	136	8	6401_DN
Drug	CHEMBL83995	DNAH9 DYNC1H1	3.54e-05	2	136	2	CID009571169
Disease	Pitt-Hopkins syndrome (implicated_via_orthology)	TCF4 TCF3	6.03e-05	3	133	2	DOID:0060488 (implicated_via_orthology)
Disease	Craniofacial Abnormalities	TCF4 COL11A2 TFAP2B ZIC5 FGD1 RAI1	7.82e-05	156	133	6	C0376634
Disease	monocyte count	TCF4 TCF3 RIN3 CD300LF WBP1L THEM5 DIDO1 TNFRSF10A LCT PPP1R10 L3MBTL1 PTPRH ZMIZ2 NYAP1 MN1 RAI1	3.05e-04	1320	133	16	EFO_0005091
Disease	coronary artery disease	HJV COL4A4 CD300LF WBP1L ZNF831 FCHO1 TFAP2B ZEB2 GGT7 IGF2R RBMX ASTN2 WNK2 RAI1 PHACTR1	3.27e-04	1194	133	15	EFO_0001645
Disease	Common Migraine	ASTN2 PHACTR1	4.17e-04	7	133	2	C0338480
Disease	acisoga measurement	PAOX IGF2R	4.17e-04	7	133	2	EFO_0800068
Disease	Congenital Hand Deformities	TFAP2B ADAMTSL2	5.55e-04	8	133	2	C0018566
Disease	Growth Disorders	FGD1 RAI1 ADAMTSL2	5.73e-04	36	133	3	C0018273
Disease	renal cell carcinoma	CRTC1 ZEB2 PDZD2	9.04e-04	42	133	3	EFO_0000681
Disease	collagen disease (implicated_via_orthology)	COL4A4 COL4A6	1.29e-03	12	133	2	DOID:854 (implicated_via_orthology)
Disease	cleft palate (is_implicated_in)	COL11A2 MTHFD1	1.29e-03	12	133	2	DOID:674 (is_implicated_in)
Disease	colon carcinoma (is_marker_for)	KMT2D IGF2R	1.52e-03	13	133	2	DOID:1520 (is_marker_for)
Disease	age at menarche	TCF4 CRTC1 SIX3 TFAP2B DSCAML1 GGT7 MSANTD1 ZIC5 HACE1	1.53e-03	594	133	9	EFO_0004703
Disease	breast cancer (is_marker_for)	KMT2B GHR KMT2D L3MBTL1 MAP2K2	1.54e-03	185	133	5	DOID:1612 (is_marker_for)
Disease	Prostatic Neoplasms	ONECUT2 ETV4 COL5A3 IRS1 TNFRSF10A GHR KMT2D IGF2R CD276	1.96e-03	616	133	9	C0033578
Disease	Malignant neoplasm of prostate	ONECUT2 ETV4 COL5A3 IRS1 TNFRSF10A GHR KMT2D IGF2R CD276	1.96e-03	616	133	9	C0376358
Disease	pain	ONECUT2 TCF4 PRSS16 ASTN2 PHACTR1	1.99e-03	196	133	5	EFO_0003843
Disease	Situs ambiguus	BCL9L DNAH9	2.04e-03	15	133	2	C0266642
Disease	response to vaccine	STK35 BTNL2 ASTN2 DNAH9	2.30e-03	122	133	4	EFO_0004645
Disease	migraine without aura, susceptibility to, 4	ASTN2 PHACTR1	2.32e-03	16	133	2	MONDO_0011847
Disease	loneliness measurement	TCF4 FAM180B FNBP4 BTNL2	2.44e-03	124	133	4	EFO_0007865
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	KMT2B SRRM2	2.62e-03	17	133	2	DOID:0060307 (is_implicated_in)
Disease	obesity (implicated_via_orthology)	TCF4 TCF3 ETV4 IRS1 ZFHX2	2.96e-03	215	133	5	DOID:9970 (implicated_via_orthology)
Disease	attention deficit hyperactivity disorder, schizophrenia	TCF4 TSNARE1 RAI1	3.05e-03	64	133	3	EFO_0003888, MONDO_0005090
Disease	Coronary Arteriosclerosis	DDAH2 IRS1 PHACTR1	3.19e-03	65	133	3	C0010054
Disease	Coronary Artery Disease	DDAH2 IRS1 PHACTR1	3.19e-03	65	133	3	C1956346
Disease	unipolar depression, mood disorder	TCF4 NR1H3 KLHL29 ASTN2	3.22e-03	134	133	4	EFO_0003761, EFO_0004247
Disease	sensorineural hearing loss (implicated_via_orthology)	DNAH17 DNAH9	3.28e-03	19	133	2	DOID:10003 (implicated_via_orthology)
Disease	breast carcinoma (is_marker_for)	CA9 KMT2D IGF2R	3.33e-03	66	133	3	DOID:3459 (is_marker_for)
Disease	lung non-small cell carcinoma (is_implicated_in)	CA9 TYMP PAOX KMT2D	3.67e-03	139	133	4	DOID:3908 (is_implicated_in)
Disease	serum metabolite measurement	COL4A4 PYROXD2 THEM5 PAOX TCF23 IGF2R PTPRH DNAH17 PTRH1 ALDH3B2 PHACTR1	3.74e-03	945	133	11	EFO_0005653
Disease	Antimigraine preparation use measurement	ASTN2 PHACTR1	4.00e-03	21	133	2	EFO_0009939
Disease	Arthrogryposis	SLC18A3 DYNC1H1	4.00e-03	21	133	2	C0003886
Disease	osteoporosis (biomarker_via_orthology)	IRS1 GHR	4.39e-03	22	133	2	DOID:11476 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGNPGLPGTRHSVGM	PTRH1	36	Q86Y79
SASGMTPGLGHRVPE	C2orf16	346	Q68DN1
MAHLRSPSGFGDPGK	ERICH6	1	Q7L0X2
IKSHMSGSPGPGGSN	ESYT2	686	A0FGR8
TGPHAPILAMAGGHV	BTNL10	36	A8MVZ5
PSHGGPKPSAESDMG	ASAP3	511	Q8TDY4
GMRGEPGLPGSSGHQ	COL4A6	1136	Q14031
MAHIPSGGAPAAGAA	CPNE2	1	Q96FN4
GGGRAEGPRSLAAMP	CYP27C1	61	Q4G0S4
HPNGGTEQGARGSMP	CYBRD1	236	Q53TN4
VAGLGSAPSIHMEGP	BTNL2	141	Q9UIR0
PGMSGHNGSRGDPGF	COL4A4	136	P53420
GSPGMGVHVGAALGA	CD276	6	Q5ZPR3
LLSVPFGGVGHSGMG	ALDH3B2	316	P48448
GPMHGFGFGLPTSRA	BCKDK	361	O14874
MAAAGARLSPGPGSG	ASTN2	1	O75129
PRMQEDSPLGGGSSG	CA9	41	Q16790
GMGDSLSLHGLGHPG	TFAP2B	161	Q92481
HTEGFSGPSPGDGAM	ETV4	281	P43268
PGRPVSGHGMDSRPA	MAP2K2	301	P36507
GMPSAGIPSAGGEEH	RBM12	691	Q9NTZ6
AGAPGRGASEGLPRM	RAI1	1041	Q7Z5J4
SGGTRGPPSRGGHMD	RBMX	116	P38159
MGEPGQSPSPRSSHG	HJV	1	Q6ZVN8
MPHSAGGTAGVGLEA	NR1H3	46	Q13133
PGHLRGELMPHGSSE	CAPN15	756	O75808
PGPGGTMKRHSSRDA	FCHO1	391	O14526
HPTGASGMAAAEGPG	MSANTD1	16	Q6ZTZ1
IIGPSHNGAMGGLGS	TCF4	421	P15884
HPGTSVLEGGAAGSM	NHSL1	1261	Q5SYE7
IVAPHSSGLGGGGVM	GGT7	176	Q9UJ14
MHLVAGDSPGSGPHL	L3MBTL1	1	Q9Y468
AMDGGDPPLSGTTHI	PCDHGB1	211	Q9Y5G3
AALRGAGPGAEGMTP	PDZD2	1321	O15018
VPHGGFANIMGGSGL	HACE1	841	Q8IYU2
MESLGTLHGPAGGGS	ONECUT2	26	O95948
GAAGETGPMGERGHP	COL11A2	931	P13942
PAGGRPPAATGHSMV	MEGF8	381	Q7Z7M0
AGGTGPLMHPDAAAA	POU3F1	16	Q03052
FPMGHGSSPSLPGVA	LCT	461	P09848
FGHPGLDMELGPSQG	ADAMTSL2	386	Q86TH1
EIVAAGAMGSSHGGP	KMT2B	2006	Q9UMN6
GTPPATGMGSQARPH	TEPSIN	146	Q96N21
ARGGAPPHAGEGEMA	GGN	216	Q86UU5
GRPMSSGAHGEEGSA	COX6A1	21	P12074
MAGAGGQHHPPGAAG	DGKH	1	Q86XP1
HSSLLGGPQGPGGMS	IRS1	1056	P35568
RGGSGAMAEAPGPSG	H1-7	16	Q75WM6
AMAEAPGPSGESRGH	H1-7	21	Q75WM6
HSGDGVTKAGPMGLP	PHACTR1	346	Q9C0D0
PSAPSGGAPIRDMGH	OBSCN	6986	Q5VST9
GGAPIRDMGHPQGSK	OBSCN	6991	Q5VST9
GPMIHSGSVVGAGLP	CLCN6	201	P51797
SLHLIMGGAPAGPAG	DNAH17	1836	Q9UFH2
AGRPGTGEHVPGSEM	GHR	576	P10912
GMSTPGSSPQHRPAG	CRTC1	296	Q6UUV9
PRAGGPHTKMGGSRD	DSCAML1	2011	Q8TD84
MGHLSSHLPGRGPEE	CD300LF	266	Q8TDQ1
PGPGGGMAHGTTRHL	IGFLR1	271	Q9H665
PSTAPGGSGAGEERM	IL2RB	441	P14784
RLQQPHGAMAPTGGG	BCL9L	1231	Q86UU0
QGQREPGPHALGMSG	DIDO1	1751	Q9BTC0
GVEPGMPESPGHLTG	BAHD1	36	Q8TBE0
ETGPGSPSGHAMGAS	G6PC2	106	Q9NQR9
APDSGPEAGGLHSGM	BAALC	41	Q8WXS3
LSSMGGGGDAAPLHS	DYNC1H1	1766	Q14204
GMASDIPGLHLPGGG	GBF1	636	Q92538
GRSGSMDPSGAHPSV	KHDRBS1	16	Q07666
DTRGPSSHEMRGGPL	CSTF2T	371	Q9H0L4
SSHEMRGGPLGDPRL	CSTF2T	376	Q9H0L4
HLTMSGAPAGPAGTG	DNAH9	1861	Q9NYC9
TGPGLPREGARGHMD	C1orf127	461	Q8N9H9
MGTPGEGLGRCSHAL	DDAH2	1	O95865
VSGPSHLRGLCGMGG	DDAH2	166	O95865
LPHTARGLGAAEMPG	FAM216A	6	Q8WUB2
MGPPHSGPGGVRVGA	EFNB3	1	Q15768
MKPGPPHRAGAAHGA	SDC3	1	O75056
MHGGGPTVTAGLPLP	MTHFD1	706	P11586
EVGDVGSMGPHGAPG	COL5A3	1161	P25940
GGSGVIMEHPGEESP	FAM171B	766	Q6P995
GALAELCPPGGSHRM	MLPH	271	Q9BV36
LCPPGGSHRMALGTA	MLPH	276	Q9BV36
MIRHAGAPARGDPTG	RIN3	1	Q8TB24
GFLPGGGSLHSTMTP	HGD	356	Q93099
GTMLAGFRLHTGPLP	MED19	146	A0JLT2
MESTGSVGEAPGGPR	PAOX	1	Q6QHF9
TSPHGGAMGAAAGVL	NYAP1	511	Q6ZVC0
GGLQDGGPMLPSQHA	MN1	391	Q10571
RMGGSGLPADCGPHD	MN1	646	Q10571
PHAGQPMDSTSVGGG	FAM180B	26	Q6P0A1
AAGVAGMGPHLSPSL	FOXA2	96	Q9Y261
GMPGLGPITGHRDSM	FOXN4	106	Q96NZ1
MGAAAGRSPHLGPAP	IGF2R	1	P11717
GLDISSPGMSGHRQG	TAF7	196	Q15545
SSAEGHVGQGAPGLM	RHOXF1	31	Q8NHV9
PSGPGGEMGVCEKHR	TRIM27	86	P14373
IAHMRGGGEGPTRTP	SLC18A3	61	Q16572
SGGTRGPPSRGGHMD	RBMXL1	116	Q96E39
SAGDHNGMLSVPAPG	SRRM2	2486	Q9UQ35
SGLMGRTLHREPPAG	SNAP47	376	Q5SQN1
PVSLPAAGMGHQARG	FNBP4	841	Q8N3X1
GSFPGGHVPDMGSGL	MYEF2	191	Q9P2K5
PHPNSDSMRGDGDGL	PIANP	141	Q8IYJ0
MHGHRAPGGAGPSEP	FGD1	1	P98174
MPGDFHLGDSGGPLV	PRSS47P	266	A8MTI9
GLMHGTCPETSGGLL	SEPHS1	311	P49903
GGGGSRAPPEELSMF	SIX3	66	O95343
SPMHPSAGGQRGGFG	SUPT5H	671	O00267
GASRGHPIPHGGMQG	SAFB	881	Q15424
GGGPRDPDGHSMSLP	C11orf42	306	Q8N5U0
GGLHDFRSPPPGMGL	SFPQ	26	P23246
MGHQESPLARAPAGG	STK35	1	Q8TDR2
PHAGMNGELTSPGAA	TLE1	376	Q04724
ESAPGTIMNGHGGGR	UBAP2	636	Q5T6F2
HLNMAAGSGVPGSGL	ZNF653	336	Q96CK0
GTGEPGPKFHLASGM	TVP23C	261	Q96ET8
AAGPHGRMAGPSTTR	TSNARE1	106	Q96NA8
HLREGGGAMGTPSPA	ZFHX2	791	Q9C0A1
ASGFTGPMSLGGRHA	TCF3	426	P15923
AHPGGGVMGAAGRNA	PYROXD2	556	Q8N2H3
EGPPGFAHGGSLAAM	THEM5	151	Q8N1Q8
EGLSGASSRPPMGLG	ROBO3	941	Q96MS0
LGHLSGRGPSPRSEM	nan	21	Q7L0L9
GGEGSTDGGMSPSHP	PPP1R3F	511	Q6ZSY5
PGMEGTAALHGDSPA	TACC2	1756	O95359
GERGLSGPSGPGHMA	SAFB2	881	Q14151
SGPSGPGHMASRGGV	SAFB2	886	Q14151
MAGLGTGPAAASPHS	PHLDB1	931	Q86UU1
GRGALPTSMGQHGPS	TNFRSF10A	51	O00220
LQHGGPRGPSVPAGM	ZMIZ2	196	Q8NF64
HMATALPLGPGASGL	TMEM253	61	P0C7T8
EEEGPGGAHPAGGVM	ZNF212	201	Q9UDV6
ARGPPAMPGVGHSQT	TCF23	6	Q7RTU1
PPSDMGTVGGQASHP	WNK2	1741	Q9Y3S1
GMHEGASERPLSPGA	ZNF831	236	Q5JPB2
MNGGLGATSPLGVHP	ZEB2	416	O60315
HRPHEGPGGGMGNSS	PPP1R10	751	Q96QC0
MGNSSGHRPHEGPGG	PPP1R10	761	Q96QC0
MEGGPPIVHCSAGVG	PTPRH	1011	Q9HD43
GEGSLGPGSVMRGHP	PRSS16	101	Q9NQE7
GPGSVMRGHPAALAP	PRSS16	106	Q9NQE7
PMISGRGLGHTGGTL	TYMP	141	P19971
APGMEPSGSVAGLGE	WBP1L	191	Q9NX94
SGPSESRPYHGMHGG	SF1	371	Q15637
HSGGGPGAQHSAMPA	TMEM38A	266	Q9H6F2
RGPGMGVHVPATPQG	TBCEL	26	Q5QJ74
TAPAAAMHGAPLGGE	ZIC5	206	Q96T25
AMHGAPLGGEQRSGT	ZIC5	211	Q96T25
SSHGDLGPPDTGMGD	TRERF1	421	Q96PN7
APGPGGESSGFMDHL	GOLGA8CP	411	A6NN73
RPGPTAVGNGHMAGP	KLHL29	246	Q96CT2
LLGSPDPEGGGSLSM	KMT2D	1226	O14686