Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainEGF

SELE HBEGF LAMC3 HHIP TENM4 MEGF6 CFC1 CFC1B NOTCH3 MASP2

4.42e-0623512610SM00181
DomainEGF-like_dom

SELE HBEGF LAMC3 HHIP TENM4 MEGF6 CFC1 CFC1B NOTCH3 MASP2

7.37e-0624912610IPR000742
DomainEGF_1

SELE HBEGF LAMC3 HHIP TENM4 MEGF6 CFC1 CFC1B NOTCH3 MASP2

9.08e-0625512610PS00022
DomainEGF-like_CS

SELE HBEGF LAMC3 HHIP TENM4 MEGF6 CFC1 CFC1B NOTCH3 MASP2

1.11e-0526112610IPR013032
DomainEGF_2

SELE HBEGF LAMC3 HHIP TENM4 MEGF6 CFC1 CFC1B NOTCH3 MASP2

1.27e-0526512610PS01186
DomainEGF_3

SELE HBEGF HHIP TENM4 MEGF6 CFC1 CFC1B NOTCH3 MASP2

3.12e-052351269PS50026
DomainNPIP

NPIPB3 NPIPB5 NPIPB13

1.03e-04141263IPR009443
DomainCFC

CFC1 CFC1B

1.35e-0431262PF09443
DomainCryptic/Cripto_CFC-dom

CFC1 CFC1B

1.35e-0431262IPR019011
DomainWSC

PKD1 WSCD2

4.46e-0451262SM00321
DomainWSC

PKD1 WSCD2

4.46e-0451262PS51212
DomainIP_trans

PITPNM2 PITPNM1

4.46e-0451262PF02121
DomainWSC_carb-bd

PKD1 WSCD2

4.46e-0451262IPR002889
DomainWSC

PKD1 WSCD2

4.46e-0451262PF01822
DomainLNS2

PITPNM2 PITPNM1

6.65e-0461262IPR013209
DomainPI_transfer

PITPNM2 PITPNM1

6.65e-0461262IPR001666
DomainLNS2

PITPNM2 PITPNM1

6.65e-0461262SM00775
DomainDDHD

PITPNM2 PITPNM1

6.65e-0461262PF02862
DomainDDHD

PITPNM2 PITPNM1

6.65e-0461262PS51043
DomainDDHD_dom

PITPNM2 PITPNM1

6.65e-0461262IPR004177
DomainLNS2

PITPNM2 PITPNM1

6.65e-0461262PF08235
DomainLNS2/PITP

PITPNM2 PITPNM1

6.65e-0461262IPR031315
DomainDDHD

PITPNM2 PITPNM1

6.65e-0461262SM01127
DomainEGF_extracell

HHIP TENM4 MEGF6 NOTCH3

7.19e-04601264IPR013111
DomainEGF_2

HHIP TENM4 MEGF6 NOTCH3

7.19e-04601264PF07974
DomainMeTrfase_RsmB/NOP2

NSUN5 NSUN5P2

1.23e-0381262IPR001678
DomainMethyltr_RsmB-F

NSUN5 NSUN5P2

1.23e-0381262PF01189
DomainOrgcat_transp/SVOP

SLC22A7 SLC22A1

1.58e-0391262IPR004749
Pubmed

Characterization of two novel genes, WBSCR20 and WBSCR22, deleted in Williams-Beuren syndrome.

NSUN5P1 NSUN5 NSUN5P2

2.18e-074133311978965
Pubmed

Identification of additional transcripts in the Williams-Beuren syndrome critical region.

NSUN5P1 NSUN5 NSUN5P2

8.82e-0611133312073013
Pubmed

Cognitive deficits in mice lacking Nsun5, a cytosine-5 RNA methyltransferase, with impairment of oligodendrocyte precursor cells.

NSUN5 NSUN5P2

1.45e-052133230485550
Pubmed

In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons.

GRIN2C GRIN2D

1.45e-052133229651654
Pubmed

Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes.

GRIN2C GRIN2D

1.45e-052133231110197
Pubmed

Mice with NOP2/sun RNA methyltransferase 5 deficiency die before reaching puberty due to fatal kidney damage.

NSUN5 NSUN5P2

1.45e-052133238712768
Pubmed

Enhanced function of NR2C/2D-containing NMDA receptor in the nucleus accumbens contributes to peripheral nerve injury-induced neuropathic pain and depression in mice.

GRIN2C GRIN2D

1.45e-052133235057644
Pubmed

RNA-methyltransferase Nsun5 controls the maternal-to-zygotic transition by regulating maternal mRNA stability.

NSUN5 NSUN5P2

1.45e-052133236495115
Pubmed

The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.

CFC1 CFC1B

1.45e-052133211174844
Pubmed

NMDA receptors containing GluN2C and GluN2D subunits have opposing roles in modulating neuronal oscillations; potential mechanism for bidirectional feedback.

GRIN2C GRIN2D

1.45e-052133231786200
Pubmed

A functional floxed allele of Pkd1 that can be conditionally inactivated in vivo.

MEOX2 PKD1

1.45e-052133215579506
Pubmed

Clearance of human factor XIa-inhibitor complexes in rats.

F11 SERPINF2

1.45e-05213328703832
Pubmed

Rare loss of function mutations in N-methyl-D-aspartate glutamate receptors and their contributions to schizophrenia susceptibility.

GRIN2C GRIN2D

1.45e-052133229317596
Pubmed

Identification of differentially expressed genes in mouse development using differential display and in situ hybridization.

CFC1 CFC1B

1.45e-052133211327798
Pubmed

Subtractive hybridization identifies chick-cripto, a novel EGF-CFC ortholog expressed during gastrulation, neurulation and early cardiogenesis.

CFC1 CFC1B

1.45e-052133211024280
Pubmed

Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth.

NSUN5 NSUN5P2

1.45e-052133231722427
Pubmed

Agenesis and Hypomyelination of Corpus Callosum in Mice Lacking Nsun5, an RNA Methyltransferase.

NSUN5 NSUN5P2

1.45e-052133231174389
Pubmed

NMDA GluN2C/2D receptors contribute to synaptic regulation and plasticity in the anterior cingulate cortex of adult mice.

GRIN2C GRIN2D

1.45e-052133233766086
Pubmed

NSUN5 is essential for proper cell proliferation and differentiation of mouse preimplantation embryos.

NSUN5 NSUN5P2

1.45e-052133238670153
Pubmed

Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects.

CFC1 CFC1B

1.45e-052133211062482
Pubmed

Circadian control of bile acid synthesis by a KLF15-Fgf15 axis.

KLF15 FGF19

1.45e-052133226040986
Pubmed

BMP antagonism is required in both the node and lateral plate mesoderm for mammalian left-right axis establishment.

CFC1 CHRD CFC1B

1.52e-0513133318550712
Pubmed

Fate and function of the ventral ectodermal ridge during mouse tail development.

BMP2 CHRD FGF19

1.93e-0514133310769235
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ARHGAP32 ZNF407 DGKD NEK9 SHROOM4 AHRR MEGF6 CPEB4 WSCD2 KAZN

2.13e-054931331015368895
Pubmed

Distinct requirements for extra-embryonic and embryonic bone morphogenetic protein 4 in the formation of the node and primitive streak and coordination of left-right asymmetry in the mouse.

BMP2 CFC1 CFC1B

2.41e-0515133312361961
Pubmed

Man1, an inner nuclear membrane protein, regulates left-right axis formation by controlling nodal signaling in a node-independent manner.

BMP2 CFC1 CFC1B

3.57e-0517133318697220
Pubmed

Protein Expression Analysis in Uterine Cervical Cancer for Potential Targets in Treatment.

SEL1L NOTCH3

4.34e-053133229532409
Pubmed

Auditory pathway and auditory brainstem response in mice lacking NMDA receptor epsilon 1 and epsilon 4 subunits.

GRIN2C GRIN2D

4.34e-05313329718984
Pubmed

Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens.

GRIN2C GRIN2D

4.34e-053133235867797
Pubmed

Cloning and characterization of a novel variant (mM-rdgBbeta1) of mouse M-rdgBs, mammalian homologs of Drosophila retinal degeneration B gene proteins, and its mRNA localization in mouse brain in comparison with other M-rdgBs.

PITPNM2 PITPNM1

4.34e-053133212562526
Pubmed

Complete loss of murine Xin results in a mild cardiac phenotype with altered distribution of intercalated discs.

FLNC XIRP1

4.34e-053133219843512
Pubmed

Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs.

CFC1 CFC1B

4.34e-053133216835440
Pubmed

Pitpnm1 is expressed in hair cells during development but is not required for hearing.

PITPNM2 PITPNM1

4.34e-053133223820044
Pubmed

Filamin C is a highly dynamic protein associated with fast repair of myofibrillar microdamage.

FLNC XIRP1

4.34e-053133227206985
Pubmed

Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a hemiparkinsonian mouse model.

GRIN2C GRIN2D

4.34e-053133233421565
Pubmed

A combined laser microdissection and mass spectrometry approach reveals new disease relevant proteins accumulating in aggregates of filaminopathy patients.

FLNC XIRP1

4.34e-053133223115302
Pubmed

Chromosomal localization, genomic organization and evolution of the genes encoding human phosphatidylinositol transfer protein membrane-associated (PITPNM) 1, 2 and 3.

PITPNM2 PITPNM1

4.34e-053133215627748
Pubmed

Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin.

HJV BMP2

4.34e-053133218287331
Pubmed

Aciculin interacts with filamin C and Xin and is essential for myofibril assembly, remodeling and maintenance.

FLNC XIRP1

4.34e-053133224963132
Pubmed

Soluble repulsive guidance molecule c/hemojuvelin is a broad spectrum bone morphogenetic protein (BMP) antagonist and inhibits both BMP2- and BMP6-mediated signaling and gene expression.

HJV BMP2

4.34e-053133220530805
Pubmed

Differential involvement of sarcomeric proteins in myofibrillar myopathies: a morphological and immunohistochemical study.

FLNC XIRP1

4.34e-053133219151983
Pubmed

Divergent origins and concerted expansion of two segmental duplications on chromosome 16.

NPIPB3 NPIPB5

4.34e-053133211948212
Pubmed

Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels.

GRIN2C GRIN2D

4.34e-05313329480759
Pubmed

Fibrocystin/Polyductin releases a C-terminal fragment that translocates into mitochondria and suppresses cystogenesis.

MEOX2 PKD1

4.34e-053133237845212
Pubmed

Neogenin interacts with hemojuvelin through its two membrane-proximal fibronectin type III domains.

HJV BMP2

4.34e-053133218335997
Pubmed

NSUN5 Facilitates Viral RNA Recognition by RIG-I Receptor.

NSUN5 NSUN5P2

4.34e-053133233177158
Pubmed

Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic.

BMP2 CFC1 CFC1B

5.07e-0519133328126904
Pubmed

Wnt3a links left-right determination with segmentation and anteroposterior axis elongation.

CFC1 PKD1 CFC1B

6.91e-0521133316291790
Pubmed

Cripto-independent Nodal signaling promotes positioning of the A-P axis in the early mouse embryo.

CFC1 CHRD CFC1B

7.98e-0522133318241853
Pubmed

BMP-2 and TGF-beta1 differentially control expression of type II procollagen and alpha 10 and alpha 11 integrins in mouse chondrocytes.

ITGA10 BMP2

8.67e-054133220129696
Pubmed

Functional correlation of NMDA receptor epsilon subunits expression with the properties of single-channel and synaptic currents in the developing cerebellum.

GRIN2C GRIN2D

8.67e-05413328699248
Pubmed

Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy.

BMP2 HOXB9

8.67e-05413329892669
Pubmed

Neuronal ER-plasma membrane junctions organized by Kv2-VAP pairing recruit Nir proteins and affect phosphoinositide homeostasis.

PITPNM2 PITPNM1

8.67e-054133231594866
Pubmed

Cripto in tumors and embryo development.

CFC1 CFC1B

8.67e-054133211825688
Pubmed

Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells.

MEOX2 BMP2

8.67e-054133223843612
Pubmed

Altered relative expression of BMPs and BMP inhibitors in cartilaginous areas of human fractures progressing towards nonunion.

BMP2 CHRD

8.67e-054133219058174
Pubmed

Regional and cellular localisation of BMPs and their inhibitors' expression in human fractures.

BMP2 CHRD

8.67e-054133219023570
Pubmed

Aberrant Regulation of Notch3 Signaling Pathway in Polycystic Kidney Disease.

PKD1 NOTCH3

8.67e-054133229463793
Pubmed

EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7.

EML4 NEK9

8.67e-054133232184261
Pubmed

CircRNA circUSP36 impairs the stability of NEDD4L mRNA through recruiting PTBP1 to enhance ULK1-mediated autophagic granulosa cell death.

USP36 ULK1

8.67e-054133235964538
Pubmed

Specific arrest of cardiogenesis in cultured embryonic stem cells lacking Cripto-1.

CFC1 CFC1B

8.67e-05413329576836
Pubmed

Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein.

PITPNM2 PITPNM1

8.67e-054133210022914
Pubmed

Structure of a multifunctional protein. Mammalian phosphatidylinositol transfer protein complexed with phosphatidylcholine.

PITPNM2 PITPNM1

8.67e-054133211104777
Pubmed

Role of the carboxy-terminal region of the GluR epsilon2 subunit in synaptic localization of the NMDA receptor channel.

GRIN2C GRIN2D

8.67e-05413329768843
Pubmed

Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.

GRIN2C GRIN2D

8.67e-054133236309015
Pubmed

Wapl is an essential regulator of chromatin structure and chromosome segregation.

MEOX2 ESPL1

8.67e-054133223975099
Pubmed

Role of the EGF-CFC gene cripto in cell differentiation and embryo development.

CFC1 CFC1B

8.67e-054133211992720
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PITPNM2 FLNC HIVEP2 ZNF48 PAPLN LAMC3 GRIN2D MEGF6 PKD1 SEC16A ZNF398 ULK1 TTC5 ESPL1

9.02e-0511051331435748872
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

MXD3 RNF130 HIVEP2 TUT1 E4F1 MEOX2 AHRR HOXB9 VSX2 TRIM47 PYGO1

9.31e-057091331122988430
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

JCAD ARHGAP32 AMPD2 HIVEP2 NCKAP5L NEK9 ENKD1 PRRC2C SEC16A MTCL1 ZNF598 ZC3HAV1

1.22e-048611331236931259
Pubmed

Endogenous Nodal signaling regulates germ cell potency during mammalian testis development.

CFC1 CFC1B DNMT3L

1.33e-0426133323034635
Pubmed

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.

GRIN2C GRIN2D

1.44e-045133226919761
Pubmed

Distinct distributions of five NMDA receptor channel subunit mRNAs in the brainstem.

GRIN2C GRIN2D

1.44e-04513327518475
Pubmed

Distinct spatiotemporal expressions of five NMDA receptor channel subunit mRNAs in the cerebellum.

GRIN2C GRIN2D

1.44e-04513327518474
Pubmed

Synapse-selective impairment of NMDA receptor functions in mice lacking NMDA receptor epsilon 1 or epsilon 2 subunit.

GRIN2C GRIN2D

1.44e-04513329147327
Pubmed

Neurotransmission and bipolar disorder: a systematic family-based association study.

GRIN2C GRIN2D

1.44e-045133218444252
Pubmed

Distinct gene expression of the N-methyl-D-aspartate receptor channel subunit in peripheral neurons of the mouse sensory ganglia and adrenal gland.

GRIN2C GRIN2D

1.44e-04513328015722
Pubmed

Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain.

GRIN2C GRIN2D

1.44e-045133215003177
Pubmed

GABAA, GABAC, and NMDA receptor subunit expression in the suprachiasmatic nucleus and other brain regions.

GRIN2C GRIN2D

1.44e-04513327723623
Pubmed

Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor.

GRIN2C GRIN2D

1.44e-045133212082569
Pubmed

Heterozygous deletion of NR1 subunit of the NMDA receptor alters ethanol-related behaviors and regional expression of NR2 subunits in the brain.

GRIN2C GRIN2D

1.44e-045133221945132
Pubmed

A differential display strategy identifies Cryptic, a novel EGF-related gene expressed in the axial and lateral mesoderm during mouse gastrulation.

CFC1 CFC1B

1.44e-04513329053319
Pubmed

Roles of the glutamate receptor epsilon2 and delta2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex.

GRIN2C GRIN2D

1.44e-045133211488959
Pubmed

Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP.

FLNC XIRP1

1.44e-045133216631741
Pubmed

Developmental changes in distribution of NMDA receptor channel subunit mRNAs.

GRIN2C GRIN2D

1.44e-04513321493227
Pubmed

N-methyl-D-aspartic acid receptor structure and function.

GRIN2C GRIN2D

1.44e-04513328036251
Pubmed

NMDA receptor activation by HIV-Tat protein is clade dependent.

GRIN2C GRIN2D

1.44e-045133219020013
Pubmed

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.

GRIN2C GRIN2D

1.44e-045133226875626
Pubmed

Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct.

SLC22A7 SLC22A1

1.44e-045133210751225
Pubmed

Differential distributions of the NMDA receptor channel subunit mRNAs in the mouse retina.

GRIN2C GRIN2D

1.44e-04513327510577
Pubmed

Self-regulated left-right asymmetric expression of Pitx2c in the developing mouse limb.

CFC1 CFC1B

1.44e-045133225224222
Pubmed

Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene.

GRIN2C GRIN2D

1.44e-04513328756432
Pubmed

The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis.

SEC16A ULK1

1.44e-045133227203176
Pubmed

Differential interaction of NMDA receptor subtypes with the post-synaptic density-95 family of membrane associated guanylate kinase proteins.

GRIN2C GRIN2D

1.44e-045133218233995
Pubmed

Distinct spatiotemporal distributions of the N-methyl-D-aspartate receptor channel subunit mRNAs in the mouse cervical cord.

GRIN2C GRIN2D

1.44e-04513327929904
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

MXD3 GSX1 HIVEP2 ZNF407 ZKSCAN7 E4F1 MEOX2 HOXB9 ZNF398 VSX2 DNMT3L PYGO1

1.45e-048771331220211142
Pubmed

Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates.

BMP2 HHIP VSX2

1.50e-0427133315075292
Pubmed

Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps.

ONECUT2 IGFBPL1 BMP2

1.67e-0428133317698011
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

MXD3 SLC22A7 BMP2 AHRR SLC22A1 PYGO1

1.72e-04212133619521566
Pubmed

Requirements for Neurogenin2 during mouse postnatal retinal neurogenesis.

IGFBPL1 RP1L1 VSX2

1.86e-0429133330048641
Cytoband16q24

IL17C EMC8 CBFA2T3

1.57e-0517133316q24
Cytoband16p12.2

NPIPB4 NPIPB3 NPIPB5

1.72e-0437133316p12.2
Cytoband16p13.3

FLYWCH1 E4F1 ZSCAN10 PKD1 ZNF598

7.53e-04244133516p13.3
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

HIVEP2 ZNF48 KLF15 ZNF407 ZKSCAN7 E4F1 ZNF786 ZXDB ZSCAN10 ZNF398 ZNF598 GLIS1

1.45e-04718861228
GeneFamilyPhosphatidylinositol transfer proteins

PITPNM2 PITPNM1

3.31e-0468621151
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2C GRIN2D

4.62e-0478621201
GeneFamilyHOXL subclass homeoboxes

GSX1 MEOX2 HOXB9

1.94e-0352863518
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SELE CSMD1 MASP2

2.53e-03578631179
GeneFamilyAtypical dual specificity phosphatases

RNGTT DUSP23

3.26e-0318862896
GeneFamilyZinc fingers MYND-type

CBFA2T3 USP19

4.43e-032186287
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA10 LAMC3 CBFA2T3 RBM20 WDR17 NOTCH3

1.29e-061151336ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA10 LAMC3 CBFA2T3 RBM20 WDR17 NOTCH3

1.29e-0611513367a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA10 LAMC3 CBFA2T3 RBM20 WDR17 NOTCH3

1.29e-061151336c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAPLN DGKD MDGA2 LAMC3 CBFA2T3 WDR17 NOTCH3

1.33e-0618313378a799807fbf24456a9811e0c64068187940a2f71
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NPIPB11 MDGA2 TENM4 NPIPB13 PRRC2C CPEB4 CSMD1

1.48e-06186133723b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellCOPD-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

SELE USP36 DGKD SFMBT2 MEOX2 SHROOM4 DUSP23

1.96e-0619413378dcde77767b23e75360adb316cdccf56a00e3726
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZKSCAN7 HPDL NEK9 BMP2 AHRR KAZN

6.73e-06153133661fe71e32fc9c8cad875bc087aad0b0ff680bf45
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEL1L FLYWCH1 PAPLN LAMC3 AHRR TENM4

1.00e-051641336d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNFRSF6B LAMC3 TUT1 BMP2 HHIP CFC1

1.07e-0516613363b67064a5149e72f895344d938c64b8ff65247f5
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP32 PAPLN DGKD CBFA2T3 WDR17 NOTCH3

1.23e-0517013365570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

USP36 NPIPB4 EML4 ZNF407 PRRC2C ZC3HAV1

1.27e-0517113362e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ISLR2 RBM20 CSMD1 WDR17 GLIS1 NOTCH3

1.27e-0517113364ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHS1 PITPNM1 ZNF598 FGF19 PLXNB1 NOTCH3

1.40e-051741336207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 HBEGF BMP2 SLC22A1 PLXNB1 NOTCH3

1.54e-05177133665709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 HBEGF BMP2 SLC22A1 PLXNB1 NOTCH3

1.54e-0517713368684d47a547e2a06496f15e8da0200ecddc431e0
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRIN2C CBFA2T3 MEGF6 TRIM47 GLIS1 NOTCH3

1.59e-0517813369fc5688cf705a74398d24e10e0aab4758612e72b
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELE MDGA2 ZKSCAN7 SHROOM4 MEGF6 TRIM47

1.65e-051791336a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELE MDGA2 ZKSCAN7 SHROOM4 MEGF6 TRIM47

1.92e-051841336f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELE MDGA2 ZKSCAN7 SHROOM4 MEGF6 TRIM47

1.92e-0518413368bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP32 PAPLN MDGA2 LAMC3 CBFA2T3 NOTCH3

1.92e-051841336327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV XIRP1 GRIN2C RBM20 IGFBPL1 PZP

2.24e-051891336e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV XIRP1 GRIN2C RBM20 IGFBPL1 PZP

2.24e-051891336b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ISLR2 LAMC3 NCKAP5L BMP2 MEGF6

2.37e-051911336b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCellMatrixFB-Fibroblast-D_(Pericyte)|MatrixFB / shred on cell class and cell subclass (v4)

HBEGF ITGA10 CBFA2T3 BMP2 MEGF6 NOTCH3

2.44e-051921336630444302511f511ec6976bc045a3b4b9d8d4547
ToppCellParenchymal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHS1 PAPLN MEOX2 TENM4 TRIM47 MMP26

2.99e-0519913366f5ef959b51eccf1ffc2e5ddf0d83c62ca2257b2
ToppCellParenchymal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHS1 PAPLN MEOX2 TENM4 TRIM47 MMP26

2.99e-0519913361aa99d21bf61b86df4a966dc47634044430aa39f
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Cd9_(Mural.Rgs5Acta2.Cd9)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

HJV XIRP1 HPDL MEOX2

7.15e-057413347c7e45cf219b0be5cf0d0e5ea5daeb32284c8ccd
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Cd9_(Mural.Rgs5Acta2.Cd9)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

HJV XIRP1 HPDL MEOX2

7.15e-057413346183baf43010268f54a6db9332296338f4f74009
DiseaseWilliams-Beuren syndrome (implicated_via_orthology)

NSUN5P1 NSUN5 NSUN5P2

3.25e-05151253DOID:1928 (implicated_via_orthology)
Diseasedouble outlet right ventricle (implicated_via_orthology)

CFC1 CFC1B

5.33e-0531252DOID:6406 (implicated_via_orthology)
DiseaseHEMOCHROMATOSIS, TYPE 1

HJV BMP2

5.33e-0531252C3469186
Diseasedextro-looped transposition of the great arteries (implicated_via_orthology)

CFC1 CFC1B

1.06e-0441252DOID:0060770 (implicated_via_orthology)
Diseaseright atrial isomerism (implicated_via_orthology)

CFC1 CFC1B

1.06e-0441252DOID:0060856 (implicated_via_orthology)
DiseaseHereditary hemochromatosis

HJV BMP2

3.69e-0471252cv:C0392514
Diseasevisceral heterotaxy (is_implicated_in)

CFC1 CFC1B

1.14e-03121252DOID:0050545 (is_implicated_in)
DiseaseHereditary hemochromatosis

HJV BMP2

1.14e-03121252C0392514
DiseaseHemochromatosis

HJV BMP2

1.14e-03121252C0018995
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GRIN2C GRIN2D PLXNB1

1.19e-03491253DOID:0060037 (implicated_via_orthology)
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

HIVEP2 BMP2

1.35e-03131252DOID:0050787 (implicated_via_orthology)
DiseaseCardiotoxicity

HBEGF BMP2

1.35e-03131252C0876994
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

FLNC PKD1

1.57e-03141252DOID:898 (implicated_via_orthology)
Diseasetriacylglycerol 48:4 measurement

SFMBT2 TENM4

1.57e-03141252EFO_0010407
Diseaseglycerate measurement

ZSCAN10 SLC23A3

1.80e-03151252EFO_0021029
Diseasepancreas fat measurement

GSX1 CBFA2T3

1.80e-03151252EFO_0600049
DiseaseDNA methylation

JCAD GSX1 RNGTT SFMBT2 TENM4 KAZN CSMD1 MMP26 GLIS1

1.95e-036561259GO_0006306
Diseasechronic obstructive pulmonary disease

JCAD HIVEP2 EML4 TUT1 ARL17A TENM4 MEGF6 CPEB4 MTCL1

2.69e-036881259EFO_0000341
Diseasedilated cardiomyopathy

FLNC PKD1

3.22e-03201252EFO_0000407

Protein segments in the cluster

PeptideGeneStartEntry
AGRSRELTPFHPAHC

AHRR

606

A9YTQ3
SAHFLRAHSRCGPGL

ENKD1

161

Q9H0I2
DSCLDPGIPVNGHRH

CSMD1

871

Q96PZ7
VHTQHPLFEGGICAP

DNMT3L

61

Q9UJW3
LHAGSGPCLPHLLSR

SERPINF2

136

P08697
PHGPVSSPLLGDHRC

CD300LD-AS1

51

Q96MU5
SHPFLPHSSRCAGSG

ARL17A

121

Q8IVW1
RCDPKDFLASHAHGP

CFC1B

156

P0CG36
TFVLRPHCGEAGPIH

AMPD2

681

Q01433
HGECPFPLADHLNST

BMP2

326

P12643
AFIPHSIVLCGPVHG

BBS10

391

Q8TAM1
RCDPKDFLASHAHGP

CFC1

156

P0CG37
FVLHCIADGHPTPRL

ISLR2

256

Q6UXK2
LLHQPHCGVPDGSDT

MMP26

76

Q9NRE1
ISRHLPSVCGGRFHP

NPIPB3

691

Q92617
DFHGVAPLHLPHICS

RBM20

401

Q5T481
HLEPVAGTLPCGHTE

PZP

456

P20742
PPALFSCHLLEGHVG

NFILZ

191

A0A5F9ZHS7
SCHLLEGHVGSRPEL

NFILZ

196

A0A5F9ZHS7
RLHGRPPGFLHCASF

HJV

156

Q6ZVN8
APLPLHGVADHLGCD

RNF130

76

Q86XS8
GPHAARVRGLAFLPH

IQCN

226

Q9H0B3
RGCGFPVGEHSPHSR

MTCL1

1096

Q9Y4B5
PHRGLSTFPGAEHCL

NSUN5

391

Q96P11
ISRHLPSVCGGRFHP

NPIPB12

611

F8W0I5
VAHHGLPREGPGCSH

NPFFR1

406

Q9GZQ6
SPLCLHQPFLHAEGG

LCNL1

121

Q6ZST4
RHRTHSLCNGDSPGP

KAZN

341

Q674X7
EHGYASLCPHRSPGP

MXD3

26

Q9BW11
SGEAHPCAHVLRPPA

PSMG3-AS1

46

Q96PY0
RPIFGSLHHVPDLSC

NEK9

701

Q8TD19
RNPPELIGVHCTHGF

RNGTT

116

O60942
LLPAAPGHRGHETCP

NCKAP5L

1201

Q9HCH0
GHCHPPDLGGLEALR

FLYWCH1

476

Q4VC44
RSQPCVDVHGLGAHP

JCAD

781

Q9P266
FFPGHRESPLHRDLG

PLXNB1

1576

O43157
HPGPCHPGHSFRLLD

PEAK3

161

Q6ZS72
HPGHSFRLLDSSPCA

PEAK3

166

Q6ZS72
GGEHIPNSPFHVLAC

FLNC

1721

Q14315
AGRPLAFSDAGPHVH

FGF19

21

O95750
PHALHGLSPGACHAR

GSX1

36

Q9H4S2
CHAPLGRQHSAVSPG

GSX1

91

Q9H4S2
LLEAGGHHRPEFSSC

LSS

396

P48449
RPHRGLSTFPGAEHC

NSUN5P2

206

Q63ZY6
HEADPCLSRPCLHGG

NOTCH3

961

Q9UM47
LLASPSPHHAGRGAA

ONECUT2

61

O95948
GHLHKARDGPCEFAP

IGFBPL1

141

Q8WX77
PEHGSLVCSHPLGNF

SELE

186

P16581
SRHLPSVCGGRFHPQ

NPIPB5

691

A8MRT5
ISRHLPSVCGGRFHP

NPIPB5

816

A8MRT5
HGTPHCYSAEELPLG

IL17C

31

Q9P0M4
FGCLRSPHATAQGLH

MEOX2

6

P50222
HRGLSTFPGAEHCLR

NSUN5P1

126

Q3KNT7
PHGVVSFCDGLVHDP

PITPNM2

1171

Q9BZ72
PGPAVCAPGSLLHHA

DDX31

86

Q9H8H2
THREDGPATLPHGRF

CBFA2T3

101

O75081
GPATLPHGRFHGCLK

CBFA2T3

106

O75081
SRHLPSVCGGRFHPQ

NPIPB4

696

C9JG80
ISRHLPSVCGGRFHP

NPIPB4

821

C9JG80
HLRAESVPAHPCGFP

ARHGAP32

1396

A7KAX9
RCYHSGGPLHLGDIE

RFESD

56

Q8TAC1
SAPVNPHLREFHCGF

MDGA2

736

Q7Z553
HDCLGFCHLPLSPGE

HPDL

181

Q96IR7
SRQPGHAEHLEFPSC

HOXB9

36

P17482
SRHLPSVCGGRFHPQ

NPIPB11

706

E5RHQ5
ISRHLPSVCGGRFHP

NPIPB11

831

E5RHQ5
PEFTTLPECHGHARD

SCYL3

176

Q8IZE3
DLHPGCRHPGTRSSL

PARD6A

306

Q9NPB6
RGHCYLLSAPGPHAL

GIMAP1

101

Q8WWP7
RGISHCPPSGLYAHL

ESPL1

1586

Q14674
PFGVHLSLIECGPVH

HSD17B1

176

P14061
PDAFVCGRICTHHPG

F11

221

P03951
DREEHGPFCGKTLPH

MASP2

251

O00187
LTGLCSPFNLDEHHP

ITGA10

16

O75578
DHRVCPPLSHSESFG

DGKD

656

Q16760
PHGLRHHSCSVVGPF

KLHDC9

256

Q8NEP7
HLHPGSSGRERCSPP

KLF15

181

Q9UIH9
DQPLHSGLGSPHCFS

CPEB4

446

Q17RY0
LVDEPGHCADFHPSG

EML4

631

Q9HC35
GPGAHHTLFVDCIPL

EMC8

46

O43402
EAHKRGHTGPRPFAC

E4F1

451

Q66K89
PGYHGERCHGLSLPV

HBEGF

136

Q99075
HCRGPLATGLHPDLD

GLIS1

11

Q8NBF1
FPNGAFDHCLGHIPS

GLIS1

601

Q8NBF1
AHRCALPGAPANFSH

SLC22A7

46

Q9Y694
FLGFTPDHHCQSPGV

SLC22A1

41

O15245
HPATAEHCVRLGPTG

PKD1

501

P98161
SRHLPSVCGGRFHPQ

NPIPB13

696

A6NJU9
PISGRCLCPAGFHGH

MEGF6

1401

O75095
RHGHSSSDPVYPCGI

PYGO1

331

Q9Y3Y4
SCLASFCPAHLGPHE

TRIM47

146

Q96LD4
GHFHCVGPASPRRAQ

RPGRIP1

126

Q96KN7
ISPEIHCDGGHTFRP

SESN1

221

Q9Y6P5
HCDGGHTFRPPSVSN

SESN1

226

Q9Y6P5
AVCAHRHFLGTGKPP

TDRG1

6

Q3Y452
TAIEGTAHGEPCHFP

SEL1L

116

Q9UBV2
GRDGQPAHCHLFLQP

RECQL4

806

O94761
GAHVVTHFFCDGPPI

OR5AU1

221

Q8NGC0
GEPPFHGHRDLCFSP

HDHD5

381

Q9BXW7
SHARLPHVARGPCGS

PRRC2C

2776

Q9Y520
AHDPCVFHSPDITGL

SOCS4

346

Q8WXH5
HSSDFLPPIRGHLGS

SHROOM4

1211

Q9ULL8
GKLAHVSFPLRGPCH

PRR32

206

B1ATL7
HGADVYGLTCHPSRP

WDR17

651

Q8IZU2
HALPITDLHCGFGGP

WDR18

171

Q9BV38
PPEVFAHGLHDPGRC

HHIP

421

Q96QV1
SCQGRTHIHLAPGLP

TRPT1

146

Q86TN4
GHVFPHCGPLVLAPS

SLC23A3

186

Q6PIS1
ALPYCGHSARHDTLP

CHRD

521

Q9H2X0
PHGVVSFCDGLTHDP

PITPNM1

1086

O00562
PPRLGCIFCHGDHLL

PLEKHS1

351

Q5SXH7
GCLIAPQAGFPHAAH

ZXDB

206

P98169
FLRLHPGCGPHTTFR

USP19

331

O94966
LSHQRSHLGPKPFGC

ZNF48

291

Q96MX3
GIHREPSHAGPLDFS

ZSCAN10

66

Q96SZ4
AVPRHGAVCHTGAPD

SEC16A

496

O15027
GRPEQGAVGPHRSHC

RP1L1

811

Q8IWN7
LRSGSGPHDCRHSPH

PAPLN

621

O95428
CPDRVSVAEGPHHAG

PAPLN

666

O95428
RPVVKFCHRPSGLHG

TUT1

366

Q9H6E5
FCHRPSGLHGDVSLS

TUT1

371

Q9H6E5
RLHTGERPFSCPHCG

ZNF398

531

Q8TD17
IPHDLCLFPHLDTTG

SFMBT2

506

Q5VUG0
LRPAHLGPCSDGHYQ

TTC5

296

Q8N0Z6
PHGTLYRTDIGLPHC

TENM4

91

Q6N022
EHPPLCGRDHLSFRS

SF3B3

1151

Q15393
PHHRGLLSPGGTSCC

SKOR2

711

Q2VWA4
GDPDDTSHRGHPLCK

ZNF598

176

Q86UK7
GLHTGERPFHCPECD

ZNF786

696

Q8N393
DPGTHHLPSGDFAQC

ZKSCAN7

186

Q9P0L1
PPCSRLHICDHFTRG

ZC3HAV1

166

Q7Z2W4
GGVVPHRHLCPVTLD

ZNF407

1241

Q9C0G0
HCGFPTTRFPLHDRE

WSCD2

281

Q2TBF2
SHGHTERFDPCRPQL

HIVEP2

751

P31629
HNGEADPRPHLGGSC

TTLL10

566

Q6ZVT0
DQGHIPLARCPSGHS

XIRP1

1381

Q702N8
PEHSPRTSGLGCRLH

ULK1

541

O75385
EGGLHQDPLRHSCSP

USP36

926

Q9P275
AHAGFCLEHASCPPG

TNFRSF6B

121

O95407
SSHPRAALDGLAPGH

VSX2

46

P58304
GPPHSDSCPGLTLHR

DUSP23

46

Q9BVJ7
HHTEGPSCERCLPGF

LAMC3

726

Q9Y6N6
QHGTLPAPAGDCRVH

GRIN2C

306

Q14957
PPRHLSCSHDGLDGG

GRIN2D

1191

O15399