Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	NAD+-protein-cysteine ADP-ribosyltransferase activity	PARP11 PARP12	6.76e-05	6	43	2	GO:0140803
GeneOntologyBiologicalProcess	mRNA splicing, via spliceosome	CIRBP SCAF11 RBMXL2 SRSF4 RBMXL3 THRAP3 SRSF8 DHX9	6.50e-07	358	43	8	GO:0000398
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	CIRBP SCAF11 RBMXL2 SRSF4 RBMXL3 THRAP3 SRSF8 DHX9	6.50e-07	358	43	8	GO:0000377
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions	CIRBP SCAF11 RBMXL2 SRSF4 RBMXL3 THRAP3 SRSF8 DHX9	7.07e-07	362	43	8	GO:0000375
GeneOntologyBiologicalProcess	RNA splicing	CIRBP SCAF11 ZNF326 RBMXL2 SRSF4 RBMXL3 THRAP3 SRSF8 DHX9	7.53e-07	502	43	9	GO:0008380
GeneOntologyBiologicalProcess	regulation of mRNA processing	CIRBP RBMXL2 SRSF4 RBMXL3 THRAP3 DHX9	8.86e-07	158	43	6	GO:0050684
GeneOntologyBiologicalProcess	mRNA processing	CIRBP SCAF11 ZNF326 RBMXL2 SRSF4 RBMXL3 THRAP3 SRSF8 DHX9	1.63e-06	551	43	9	GO:0006397
GeneOntologyBiologicalProcess	positive regulation of mRNA splicing, via spliceosome	CIRBP RBMXL2 RBMXL3 THRAP3	2.09e-06	44	43	4	GO:0048026
GeneOntologyBiologicalProcess	positive regulation of mRNA processing	CIRBP RBMXL2 RBMXL3 THRAP3	3.24e-06	49	43	4	GO:0050685
GeneOntologyBiologicalProcess	regulation of RNA splicing	CIRBP ZNF326 RBMXL2 SRSF4 RBMXL3 THRAP3	4.25e-06	207	43	6	GO:0043484
GeneOntologyBiologicalProcess	regulation of mRNA splicing, via spliceosome	CIRBP RBMXL2 SRSF4 RBMXL3 THRAP3	7.04e-06	129	43	5	GO:0048024
GeneOntologyBiologicalProcess	positive regulation of RNA splicing	CIRBP RBMXL2 RBMXL3 THRAP3	8.92e-06	63	43	4	GO:0033120
GeneOntologyBiologicalProcess	mRNA metabolic process	CIRBP SCAF11 ZNF326 RBMXL2 SRSF4 RBMXL3 THRAP3 SRSF8 DHX9	9.40e-05	917	43	9	GO:0016071
GeneOntologyBiologicalProcess	negative regulation of mRNA metabolic process	CIRBP SRSF4 THRAP3 DHX9	9.57e-05	115	43	4	GO:1903312
GeneOntologyBiologicalProcess	sensory perception of mechanical stimulus	COL6A1 ITGA2 MBP PTPRQ SCN8A	1.32e-04	238	43	5	GO:0050954
GeneOntologyBiologicalProcess	positive regulation of mRNA metabolic process	CIRBP RBMXL2 RBMXL3 THRAP3 DHX9	1.96e-04	259	43	5	GO:1903313
GeneOntologyBiologicalProcess	protein auto-ADP-ribosylation	PARP11 PARP12	2.31e-04	11	43	2	GO:0070213
GeneOntologyBiologicalProcess	regulation of mRNA metabolic process	CIRBP RBMXL2 SRSF4 RBMXL3 THRAP3 DHX9	2.95e-04	443	43	6	GO:1903311
GeneOntologyBiologicalProcess	cellular response to follicle-stimulating hormone stimulus	GATA4 EPHA8	4.38e-04	15	43	2	GO:0071372
GeneOntologyBiologicalProcess	glial cell differentiation	SOX11 COL6A1 BCAN MBD1 MXRA8	5.25e-04	321	43	5	GO:0010001
GeneOntologyBiologicalProcess	ventricular cardiac muscle tissue development	GATA4 DSP MBD1	5.34e-04	76	43	3	GO:0003229
GeneOntologyBiologicalProcess	mRNA stabilization	CIRBP THRAP3 DHX9	5.54e-04	77	43	3	GO:0048255
GeneOntologyBiologicalProcess	lung morphogenesis	GATA4 SOX11 COL6A1	5.54e-04	77	43	3	GO:0060425
GeneOntologyBiologicalProcess	neuron remodeling	EPHA8 FARP2	7.88e-04	20	43	2	GO:0016322
GeneOntologyBiologicalProcess	negative regulation of mRNA catabolic process	CIRBP THRAP3 DHX9	7.92e-04	87	43	3	GO:1902373
GeneOntologyBiologicalProcess	RNA stabilization	CIRBP THRAP3 DHX9	8.19e-04	88	43	3	GO:0043489
GeneOntologyBiologicalProcess	embryonic digestive tract morphogenesis	GATA4 SOX11	8.69e-04	21	43	2	GO:0048557
GeneOntologyBiologicalProcess	response to follicle-stimulating hormone	GATA4 EPHA8	8.69e-04	21	43	2	GO:0032354
GeneOntologyBiologicalProcess	cellular response to gonadotropin stimulus	GATA4 EPHA8	9.55e-04	22	43	2	GO:0071371
GeneOntologyBiologicalProcess	cardiac muscle cell contraction	GATA4 DSP SCN8A	9.61e-04	93	43	3	GO:0086003
GeneOntologyBiologicalProcess	skeletal muscle cell differentiation	GATA4 SOX11 COL6A1	1.05e-03	96	43	3	GO:0035914
GeneOntologyCellularComponent	nuclear body	GATA4 HMBOX1 ABHD17A PARP11 SCAF11 SRSF4 THRAP3 SRSF8 MBD1 SETBP1 DHX9	1.49e-06	903	43	11	GO:0016604
Domain	RRM_1	CIRBP RBMXL2 SRSF4 RBMXL3 EIF4H SRSF8	3.09e-06	208	37	6	PF00076
Domain	RRM	CIRBP RBMXL2 SRSF4 RBMXL3 EIF4H SRSF8	3.95e-06	217	37	6	SM00360
Domain	RRM_dom	CIRBP RBMXL2 SRSF4 RBMXL3 EIF4H SRSF8	5.12e-06	227	37	6	IPR000504
Domain	RRM	CIRBP RBMXL2 SRSF4 RBMXL3 EIF4H SRSF8	5.52e-06	230	37	6	PS50102
Domain	-	CIRBP RBMXL2 SRSF4 RBMXL3 EIF4H SRSF8	7.74e-06	244	37	6	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	CIRBP RBMXL2 SRSF4 RBMXL3 EIF4H SRSF8	1.06e-05	258	37	6	IPR012677
Domain	WWE	PARP11 PARP12	2.49e-04	12	37	2	PS50918
Domain	WWE-dom	PARP11 PARP12	2.49e-04	12	37	2	IPR004170
Domain	WWE	PARP11 PARP12	2.49e-04	12	37	2	PF02825
Domain	Poly(ADP-ribose)pol_cat_dom	PARP11 PARP12	5.10e-04	17	37	2	IPR012317
Domain	PARP_CATALYTIC	PARP11 PARP12	5.10e-04	17	37	2	PS51059
Domain	PARP	PARP11 PARP12	5.10e-04	17	37	2	PF00644
Domain	-	PARP11 PARP12	5.10e-04	17	37	2	3.90.228.10
Domain	TyrKc	TEC ZAP70 EPHA8	6.99e-04	88	37	3	SM00219
Domain	Tyr_kinase_cat_dom	TEC ZAP70 EPHA8	6.99e-04	88	37	3	IPR020635
Domain	PROTEIN_KINASE_TYR	TEC ZAP70 EPHA8	9.28e-04	97	37	3	PS00109
Domain	Tyr_kinase_AS	TEC ZAP70 EPHA8	9.28e-04	97	37	3	IPR008266
Domain	RRM_dom_euk	CIRBP RBMXL2	9.41e-04	23	37	2	IPR003954
Domain	RRM_1	CIRBP RBMXL2	9.41e-04	23	37	2	SM00361
Domain	WGR_domain	PARP11 PARP12	1.03e-03	24	37	2	IPR008893
Domain	SH2	TEC RASA1 ZAP70	1.04e-03	101	37	3	PF00017
Domain	SH2	TEC RASA1 ZAP70	1.33e-03	110	37	3	SM00252
Domain	SH2	TEC RASA1 ZAP70	1.37e-03	111	37	3	PS50001
Domain	SH2	TEC RASA1 ZAP70	1.41e-03	112	37	3	IPR000980
Domain	-	TEC RASA1 ZAP70	1.41e-03	112	37	3	3.30.505.10
Domain	Pkinase_Tyr	TEC ZAP70 EPHA8	2.11e-03	129	37	3	PF07714
Domain	Ser-Thr/Tyr_kinase_cat_dom	TEC ZAP70 EPHA8	2.55e-03	138	37	3	IPR001245
Domain	VWA	COL6A1 ITGA2	5.50e-03	56	37	2	PF00092
Domain	DEAD	DDX3Y DHX9	9.19e-03	73	37	2	PF00270
Domain	DEAD/DEAH_box_helicase_dom	DDX3Y DHX9	9.19e-03	73	37	2	IPR011545
Domain	IGv	BCAN MXRA8	9.68e-03	75	37	2	SM00406
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	CIRBP SCAF11 ZNF326 SRSF4 EIF4H THRAP3	8.76e-07	258	44	6	37794589
Pubmed	Haploinsufficiency of the germ cell-specific nuclear RNA binding protein hnRNP G-T prevents functional spermatogenesis in the mouse.	RBMXL2 RBMXL3	1.56e-06	2	44	2	18562473
Pubmed	An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning.	RBMXL2 RBMXL3	1.56e-06	2	44	2	30674417
Pubmed	Preferential conduction block of myelinated axons by nitric oxide.	MBP SCN8A	1.56e-06	2	44	2	27614087
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	CIRBP SRSF4 EIF4H THRAP3 SRSF8 PARP12 MBP DHX9	3.07e-06	723	44	8	34133714
Pubmed	Adrenocortical tumorigenesis in transgenic mice expressing the inhibin alpha-subunit promoter/simian virus 40 T-antigen transgene: relationship between ectopic expression of luteinizing hormone receptor and transcription factor GATA-4.	GATA4 INHA	4.69e-06	3	44	2	15256532
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	CIRBP GATA4 DDX3Y SCAF11 ZNF326 RBMXL3 DSP THRAP3 SRSF8 PARP12	6.39e-06	1371	44	10	36244648
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	CIRBP SCAF11 ZNF326 SRSF4 EIF4H THRAP3 SRSF8 DHX9	6.87e-06	807	44	8	22681889
Pubmed	Binding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins.	RASA1 ZAP70	9.37e-06	4	44	2	7760813
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	SCAF11 ZNF326 SRSF4 THRAP3 DHX9	1.42e-05	244	44	5	29884807
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	ZNF326 SRSF4 DSP THRAP3 DHX9	1.45e-05	245	44	5	35652658
Pubmed	Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements.	SRSF4 SRSF8	2.34e-05	6	44	2	17361132
Pubmed	The thrombospondin-4 gene.	ITGA2 RASA1	2.34e-05	6	44	2	10501972
Pubmed	A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1.	ZNF326 SRSF8 DHX9	2.58e-05	45	44	3	25496916
Pubmed	Landscape of the SOX2 protein-protein interactome.	COL6A1 DSP THRAP3 DHX9	2.69e-05	136	44	4	21280222
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	HMBOX1 SCAF11 ZNF326 SRSF4 DSP THRAP3 SRSF8 MBD1 DHX9	2.91e-05	1294	44	9	30804502
Pubmed	Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.	MBD1 FARP2	3.27e-05	7	44	2	20062064
Pubmed	Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing.	SCAF11 SRSF4	3.27e-05	7	44	2	9447963
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	CIRBP ZNF326 SRSF4 DSP THRAP3 SRSF8 DHX9	3.43e-05	731	44	7	29298432
Pubmed	Proteomic analysis of the cullin 4B interactome using proximity-dependent biotinylation in living cells.	CIRBP RBMXL2 RBMXL3 DHX9	4.26e-05	153	44	4	28225217
Pubmed	TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation.	THRAP3 DHX9	4.36e-05	8	44	2	20123736
Pubmed	Prolonged Sox4 expression in oligodendrocytes interferes with normal myelination in the central nervous system.	SOX11 MBP	4.36e-05	8	44	2	17515609
Pubmed	SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1.	SRSF4 MBP	4.36e-05	8	44	2	10390541
Pubmed	Regulation of alternative splicing by SRrp86 and its interacting proteins.	SRSF4 THRAP3 SRSF8	5.27e-05	57	44	3	14559993
Pubmed	PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays.	CIRBP DHX9	5.60e-05	9	44	2	11850402
Pubmed	Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.	DDX3Y SRSF4 RASA1 EIF4H ZAP70	5.73e-05	327	44	5	15592455
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	ZNF326 SRSF4 THRAP3 SRSF8 DHX9	5.98e-05	330	44	5	33301849
Pubmed	The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control.	THRAP3 DHX9	6.99e-05	10	44	2	18596238
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	CIRBP RBMXL2 SRSF4 RBMXL3 DHX9	7.58e-05	347	44	5	16033648
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	DDX3Y RBMXL2 RBMXL3 DSP THRAP3 MBD1 DHX9	8.47e-05	844	44	7	25963833
Pubmed	Mutations in C1orf194, encoding a calcium regulator, cause dominant Charcot-Marie-Tooth disease.	COL6A1 MBP	8.54e-05	11	44	2	31199454
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	CIRBP DDX3Y RBMXL2 SRSF4 RBMXL3 DSP THRAP3 DHX9	8.73e-05	1153	44	8	29845934
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	HMBOX1 ZNF326 DSP THRAP3 MBD1 DHX9	8.89e-05	583	44	6	29844126
Pubmed	A collagen VI-dependent pathogenic mechanism for Hirschsprung's disease.	GATA4 COL6A1	1.02e-04	12	44	2	26571399
Pubmed	Rescuing the aberrant sex development of H3K9 demethylase Jmjd1a-deficient mice by modulating H3K9 methylation balance.	GATA4 DDX3Y	1.02e-04	12	44	2	28949961
Pubmed	Mouse models of adrenocortical tumors.	GATA4 INHA	1.02e-04	12	44	2	26678830
Pubmed	Impaired macroglial development and axonal conductivity contributes to the neuropathology of DYRK1A-related intellectual disability syndrome.	MBP SCN8A	1.02e-04	12	44	2	36402907
Pubmed	Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles.	ITGA2 MBP	1.02e-04	12	44	2	12843252
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	HMBOX1 SCAF11 ZNF326 DSP THRAP3 DHX9	1.09e-04	605	44	6	28977666
Pubmed	Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.	TEC RASA1 ZAP70	1.10e-04	73	44	3	24728074
Pubmed	The SARS-CoV-2 RNA interactome.	EIF4H THRAP3 PARP12	1.15e-04	74	44	3	33989516
Pubmed	CNS myelin paranodes require Nkx6-2 homeoprotein transcriptional activity for normal structure.	MBP SCN8A	1.21e-04	13	44	2	15601927
Pubmed	Genomic structure and chromosomal mapping of the murine and human Mbd1, Mbd2, Mbd3, and Mbd4 genes.	COL6A1 MBD1	1.21e-04	13	44	2	10441743
Pubmed	WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination.	MBP SCN8A	1.21e-04	13	44	2	16723544
Pubmed	Cooperation and selectivity of the two Grb2 binding sites of p52Shc in T-cell antigen receptor signaling to Ras family GTPases and Myc-dependent survival.	RASA1 ZAP70	1.21e-04	13	44	2	15688026
Pubmed	A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins).	SRSF4 SRSF8	1.21e-04	13	44	2	20516191
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	DDX3Y BCAN SRSF4 SETBP1 MBP DHX9	1.25e-04	621	44	6	22794259
Pubmed	The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.	ZNF326 SRSF4 DSP THRAP3	1.27e-04	203	44	4	35012549
Pubmed	Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors.	TEC RASA1 ZAP70	1.29e-04	77	44	3	22973453
Pubmed	Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry.	EIF4H ZAP70 MBD1	1.45e-04	80	44	3	16094384
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	HMBOX1 DDX3Y ZNF326 SRSF4 EIF4H THRAP3 PARP12 DHX9	1.50e-04	1247	44	8	27684187
Pubmed	The protein tyrosine kinase family of the human genome.	TEC ZAP70 EPHA8	1.62e-04	83	44	3	11114734
Pubmed	Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation.	RASA1 ZAP70	1.63e-04	15	44	2	10790433
Pubmed	Sox9 overexpression exerts multiple stage-dependent effects on mouse spinal cord development.	SOX11 MBP	1.63e-04	15	44	2	31724774
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	DDX3Y DSP THRAP3 DHX9	1.73e-04	220	44	4	24550385
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	DDX3Y SCAF11 ZNF326 SRSF4 DSP THRAP3 DHX9	1.81e-04	954	44	7	36373674
Pubmed	Regulation of ubiquitin-proteasome system-mediated Tip110 protein degradation by USP15.	THRAP3 DHX9	1.86e-04	16	44	2	24984263
Pubmed	Stem cell factor induces phosphatidylinositol 3'-kinase-dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells.	TEC RASA1	1.86e-04	16	44	2	11071635
Pubmed	Family-wide analysis of poly(ADP-ribose) polymerase activity.	PARP11 PARP12	1.86e-04	16	44	2	25043379
Pubmed	CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia.	TEC RASA1 THRAP3	1.86e-04	87	44	3	29991678
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	CIRBP HMBOX1 SCAF11 SRSF4 THRAP3 MBD1	1.89e-04	670	44	6	22990118
Pubmed	DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.	ZNF326 SRSF4 DHX9	1.99e-04	89	44	3	22446626
Pubmed	A quantitative protein interaction network for the ErbB receptors using protein microarrays.	TEC RASA1 ZAP70	2.06e-04	90	44	3	16273093
Pubmed	TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.	CIRBP ZNF326 THRAP3 SRSF8 DHX9	2.06e-04	430	44	5	38172120
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SRSF4 DSP THRAP3 DHX9	2.19e-04	234	44	4	36243803
Pubmed	The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells.	SRSF4 EIF4H THRAP3 DHX9	2.38e-04	239	44	4	26641092
Pubmed	An integrated genetic map of the pearl locus of mouse chromosome 13.	ITGA2 RASA1	2.64e-04	19	44	2	8828042
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	CIRBP ZNF326 SRSF4 THRAP3 SRSF8 DHX9	2.64e-04	713	44	6	29802200
Pubmed	Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.	ABHD17A COL6A1 FOXRED2 MBP	2.78e-04	249	44	4	9371744
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SCAF11 SRSF4 THRAP3 SRSF8	2.87e-04	251	44	4	31076518
Pubmed	Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation.	SOX11 SCAF11	2.93e-04	20	44	2	12447396
Pubmed	Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop.	DSP THRAP3 SRSF8 DHX9	3.28e-04	260	44	4	36199071
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	ZNF326 SRSF4 DSP THRAP3 DHX9	3.32e-04	477	44	5	31300519
Pubmed	SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function.	SOX11 MBP	3.56e-04	22	44	2	17084361
Pubmed	LncRNA H19 Regulates Breast Cancer DNA Damage Response and Sensitivity to PARP Inhibitors via Binding to ILF2.	DSP SRSF8	3.56e-04	22	44	2	37298108
Pubmed	Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.	ZNF326 THRAP3 DHX9	3.61e-04	109	44	3	29511296
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	CIRBP DDX3Y ZNF326 SRSF4 DSP THRAP3 DHX9	3.88e-04	1082	44	7	38697112
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SCAF11 RBMXL2 DSP THRAP3 MOCOS DHX9	4.09e-04	774	44	6	15302935
Pubmed	Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.	CIRBP SRSF4 DHX9	4.23e-04	115	44	3	17332742
Pubmed	Loss of Krox20 results in aortic valve regurgitation and impaired transcriptional activation of fibrillar collagen genes.	COL6A1 BCAN	4.24e-04	24	44	2	25344368
Pubmed	ERp57 is essential for efficient folding of glycoproteins sharing common structural domains.	COL6A1 ITGA2	4.61e-04	25	44	2	17170699
Pubmed	The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs.	RASA1 DHX9	4.61e-04	25	44	2	15121898
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	HMBOX1 SCAF11 RASA1 THRAP3 SETBP1 MOCOS MBP FARP2	4.96e-04	1489	44	8	28611215
Pubmed	Quantitative-trait loci analysis of cocaine-related behaviours and neurochemistry.	INHA SCN8A	4.99e-04	26	44	2	10591541
Pubmed	Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice.	GATA4 INHA	5.38e-04	27	44	2	23471215
Pubmed	Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.	RASA1 MBP	5.79e-04	28	44	2	18067320
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	DDX3Y SCAF11 THRAP3	6.04e-04	130	44	3	35545047
Pubmed	Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.	DSP MBP DHX9	6.18e-04	131	44	3	28634551
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	SCAF11 ZNF326 DSP THRAP3 DHX9	6.39e-04	551	44	5	34728620
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	DDX3Y ZAP70 THRAP3	6.46e-04	133	44	3	15144186
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	CIRBP SCAF11 ZNF326 SRSF4 THRAP3 DHX9	6.57e-04	847	44	6	35850772
Pubmed	Immunoprecipitation and mass spectrometry defines an extensive RBM45 protein-protein interaction network.	DDX3Y THRAP3 DHX9	6.89e-04	136	44	3	26979993
Pubmed	A global genomic transcriptional code associated with CNS-expressed genes.	SOX11 ZNF326 ITGA2 PARP12	6.98e-04	318	44	4	16919269
Pubmed	Interactome analysis of the human Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (hMTr1) protein.	CIRBP SRSF4 DHX9	7.19e-04	138	44	3	30320910
Pubmed	Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.	COL6A1 ITGA2	7.57e-04	32	44	2	23154389
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	SRSF4 EIF4H THRAP3 PARP12	7.92e-04	329	44	4	34316702
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	ZNF326 SRSF4 DSP THRAP3 DHX9	8.17e-04	582	44	5	20467437
Pubmed	Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.	RBMXL2 SRSF4 DSP DHX9	8.38e-04	334	44	4	30425250
Pubmed	The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.	CIRBP ZNF326 DHX9	8.63e-04	147	44	3	28977470
Pubmed	Comparative maps of human 19p13.3 and mouse chromosome 10 allow identification of sequences at evolutionary breakpoints.	CIRBP ABHD17A	9.06e-04	35	44	2	10984455
Interaction	SRSF3 interactions	CIRBP SCAF11 ZNF326 SRSF4 EIF4H THRAP3 SRSF8 DHX9	4.74e-06	522	38	8	int:SRSF3
Interaction	SNRPC interactions	GATA4 SCAF11 ZNF326 SRSF4 THRAP3 SRSF8 DHX9	1.58e-05	440	38	7	int:SNRPC
Interaction	BMI1 interactions	CIRBP GATA4 SCAF11 ZNF326 SRSF4 EIF4H THRAP3 PARP12	2.57e-05	659	38	8	int:BMI1
Interaction	SNRPA interactions	CIRBP SCAF11 ZNF326 SRSF4 THRAP3 SRSF8 DHX9	2.85e-05	482	38	7	int:SNRPA
Interaction	EPHB3 interactions	TEC RASA1 EPHA8	3.88e-05	35	38	3	int:EPHB3
Interaction	PRMT8 interactions	CIRBP SCAF11 THRAP3 DHX9	4.32e-05	104	38	4	int:PRMT8
Interaction	SNRPF interactions	GATA4 SCAF11 ZNF326 RASA1 THRAP3 DHX9	7.70e-05	385	38	6	int:SNRPF
Interaction	TAF15 interactions	CIRBP GATA4 SCAF11 ZNF326 THRAP3 DHX9	1.06e-04	408	38	6	int:TAF15
GeneFamily	RNA binding motif containing	CIRBP RBMXL2 SRSF4 RBMXL3 EIF4H	5.27e-05	213	35	5	725
GeneFamily	RNA binding motif containing\|Serine and arginine rich splicing factors	SRSF4 SRSF8	2.37e-04	12	35	2	737
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PARP11 PARP12	4.86e-04	17	35	2	684
GeneFamily	SH2 domain containing	TEC RASA1 ZAP70	9.73e-04	101	35	3	741
GeneFamily	Immunoglobulin heavy locus at 14q32.33	IGHV3-53 IGHV3-38 IGHV3-38-3	5.59e-03	187	35	3	349
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	TEC RASA1 FARP2	7.30e-03	206	35	3	682
ToppCell	COPD-Epithelial-Aberrant_Basaloid\|COPD / Disease state, Lineage and Cell class	SOX11 ITGA2 DSP MXRA8	2.26e-05	176	42	4	11d867bcb4f2471b4e13a5f7dc1c24286197f26d
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA4 SCAF11 THRAP3 DHX9	2.26e-05	176	42	4	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	AT1-AT2_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	SOX11 ITGA2 DSP MXRA8	2.26e-05	176	42	4	f86832cfeff5b3cfffe4455c1b96a1420d48ba1e
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL6A1 BCAN PTPRQ MXRA8	2.31e-05	177	42	4	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL6A1 BCAN PTPRQ MXRA8	2.31e-05	177	42	4	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA2 DSP MOCOS PTPRQ	2.41e-05	179	42	4	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	droplet-Marrow-BM\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD17A DDX3Y EIF4H PARP12	2.52e-05	181	42	4	4169a1527b9c8f5783b8cc44e3a3924f8ed9a5e2
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA2 DSP MOCOS PTPRQ	2.52e-05	181	42	4	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ABHD17A DDX3Y ZAP70 MBP	2.86e-05	187	42	4	0bca79cea4886b66350c56c61859bd71e1e7a85c
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	CIRBP ABHD17A ZAP70 MBP	2.98e-05	189	42	4	0e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA4 COL6A1 DSP MXRA8	2.98e-05	189	42	4	2a5fda73d38bdc23cf47e5335ffd4e086e990245
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|World / Disease state, Lineage and Cell class	SOX11 ITGA2 DSP MXRA8	2.98e-05	189	42	4	8030a353473da34ae92429f2d822171a2e94248f
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA4 COL6A1 DSP MXRA8	3.04e-05	190	42	4	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	3'_v3-Lung-Lymphocytic_NK\|Lung / Manually curated celltypes from each tissue	CIRBP ABHD17A ZAP70 MBP	3.23e-05	193	42	4	a98ee519e0da93ae4a2dcdda1ee8b4138dec131b
ToppCell	COVID-19_Severe-CD8+_T_activated\|World / disease group, cell group and cell class	TRAV12-3 ABHD17A DDX3Y MBP	3.23e-05	193	42	4	ddc1db516568e03be8e82b2ca770c67756418185
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX11 DDX3Y SCAF11 THRAP3	3.30e-05	194	42	4	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	3'_v3-Lung-Lymphocytic_NK-NK_CD16\|Lung / Manually curated celltypes from each tissue	CIRBP ABHD17A ZAP70 MBP	3.30e-05	194	42	4	3337042eef91a49f621058785723228cf4dfdad4
ToppCell	Control-Stromal-Myofibroblast\|Control / Disease state, Lineage and Cell class	COL6A1 ITGA2 SETBP1 MXRA8	3.37e-05	195	42	4	ffcf76cd72e43d8cf1058a49c76e0956065038bc
ToppCell	droplet-Marrow-BM-1m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD17A DDX3Y SRSF4 EIF4H	3.37e-05	195	42	4	637b06ef3967b03f7165d102d316e8b7161a817d
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ITGA2 DSP MOCOS PTPRQ	3.57e-05	198	42	4	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	Sepsis-URO-Lymphocyte-T/NK-gd_T\|URO / Disease, condition lineage and cell class	ITGA2 ZAP70 MBP SCN8A	3.57e-05	198	42	4	cb584f7754ef4e6d9ec7155022852f2d2676ab4f
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX11 COL6A1 DDX3Y MXRA8	3.57e-05	198	42	4	b086af292a508a156266c2d899ba1caf820bf61c
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL6A1 ITGA2 SETBP1 MXRA8	3.57e-05	198	42	4	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ITGA2 DSP MOCOS PTPRQ	3.64e-05	199	42	4	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	COVID-19_Severe-CD8+_T_activated\|COVID-19_Severe / disease group, cell group and cell class	TRAV12-3 ABHD17A ZAP70 MBP	3.64e-05	199	42	4	a16b961996291bd5958c3851b7fdd7b45c53e19b
ToppCell	Brain_organoid-organoid_Tanaka_cellReport\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	COL6A1 DDX3Y SCAF11 MXRA8	3.72e-05	200	42	4	b0ba486b55be18a4236bd2644f02352651f4b1fe
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ITGA2 DSP MOCOS PTPRQ	3.72e-05	200	42	4	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_large-bowel / Manually curated celltypes from each tissue	DDX3Y ZAP70 PARP12	3.94e-04	152	42	3	95944864ce7539ff8de028f5700694931338f3ff
ToppCell	Club_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	FOXRED2 DSP SETBP1	4.02e-04	153	42	3	77030b0e033f3635b1bbe7552a28c074ea7bb106
ToppCell	AT1-AT2_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	SOX11 DSP MXRA8	4.41e-04	158	42	3	3bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCell	COPD-Epithelial-Aberrant_Basaloid\|Epithelial / Disease state, Lineage and Cell class	SOX11 COL6A1 MXRA8	4.41e-04	158	42	3	8f66979e92f886d86cecbd26aaa0c5915c049734
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_D\|390C / Donor, Lineage, Cell class and subclass (all cells)	ABHD17A ZAP70 MBP	4.66e-04	161	42	3	b60b4fd34a3ad4bf1813e6cc24aa7e04f9e53e4c
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	ZNF326 SRSF4 THRAP3	4.75e-04	162	42	3	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	normal-na-Lymphocytic_NK-NK_bright-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	DDX3Y TEC MBP	4.92e-04	164	42	3	b5a91f2cbfad9a2bc38aea576085a37865df955d
ToppCell	Basal_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	SOX11 ITGA2 DSP	5.27e-04	168	42	3	48089fa2d4a0f31a72405717119b767a92571f01
ToppCell	15-Airway-Epithelial-Submucosal_gland_basal\|Airway / Age, Tissue, Lineage and Cell class	BCAN ITGA2 DSP	5.46e-04	170	42	3	61f8dd5e27df1b8d01ccfd0d25247b34aa8d182c
ToppCell	tumor_Lung-Endothelial_cells-EPCs\|Endothelial_cells / Location, Cell class and cell subclass	TEC ZAP70 MBP	5.55e-04	171	42	3	dcb6c41980008d0b9eeb54999faff77311554976
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PARP11 ITGA2 RASA1	5.55e-04	171	42	3	7c8304573b892ef9ea4e048cba9ea9fbab848dcd
ToppCell	LPS-IL1RA-Lymphocytic_NKT-T_cells-T-cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEC ZAP70 MBP	5.55e-04	171	42	3	539ea88acc6f948efdeae8b69e5c5ffaee29f1d9
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DSP SETBP1 FARP2	5.55e-04	171	42	3	c3e3ea09c73050372314a89b282e36ba5f339d73
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|390C / Donor, Lineage, Cell class and subclass (all cells)	ABHD17A ZAP70 MBP	5.55e-04	171	42	3	d6d8ea45b443d95f64720c9bc07d324148f5b239
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX11 PTPRQ MXRA8	5.65e-04	172	42	3	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	PND01-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITGA2 TEC MOCOS	5.65e-04	172	42	3	6503e85182eb6e8a40a890e393e9ac5c5350e322
ToppCell	LPS-IL1RA-Lymphocytic_NKT-T_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEC ZAP70 MBP	5.65e-04	172	42	3	0fc692be845d4225ff8b63bf9195724fc8510c2c
ToppCell	390C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	COL6A1 ZNF577 DHX9	5.65e-04	172	42	3	84d16cd7f618c94888920680bdc9e7130d73fd75
ToppCell	PND01-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITGA2 TEC MOCOS	5.65e-04	172	42	3	3c0bf7200e582ee730af49dcd86446e112226aca
ToppCell	LPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEC ZAP70 MBP	5.74e-04	173	42	3	fde1fabb8d13d05998ac3f21ecb1fde6a7a2f337
ToppCell	LPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEC ZAP70 MBP	5.74e-04	173	42	3	dcde3252ff96448d3a61039a4948c74ad321a218
ToppCell	PND10-Epithelial-Epithelial_Airway-Basal-Basal-Basal_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAM3B DSP MOCOS	5.84e-04	174	42	3	97d4a40b536a67fa52f055eab26106d041bf3220
ToppCell	PND10-Epithelial-Epithelial_Airway-Basal-Basal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAM3B DSP MOCOS	5.84e-04	174	42	3	f9f399244c7d12caf8118ec3117d477a39e35c3b
ToppCell	LPS-antiTNF-Lymphocytic_NKT-iNKT/MAIT\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEC ZAP70 MBP	5.84e-04	174	42	3	61aa89b56ebda0eba1ba675d5f036992967f670f
ToppCell	PND10-Epithelial-Epithelial_Airway-Basal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAM3B DSP MOCOS	5.84e-04	174	42	3	e8440eea7c81864defa57c89e9b569ad8033e5c5
ToppCell	LPS-antiTNF-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEC ZAP70 MBP	5.94e-04	175	42	3	98cb577df466700e72d1bbc6689205ccf2e7fcba
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAM3B DSP EPHA8	5.94e-04	175	42	3	bffa623511ceb0b9bf76d87f9a10cfadfe0e940f
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEC ZAP70 MBP	6.04e-04	176	42	3	bb41e9478373726eb460af764de0277b2d09928e
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells-T-cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEC ZAP70 MBP	6.04e-04	176	42	3	9d4a4dfeebb5a8a0f3ab18c37c8ddc2cd2158575
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|390C / Donor, Lineage, Cell class and subclass (all cells)	COL6A1 MXRA8 SCN8A	6.04e-04	176	42	3	852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	COL6A1 MXRA8 SCN8A	6.04e-04	176	42	3	d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	BCAN PTPRQ MXRA8	6.14e-04	177	42	3	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	BCAN PTPRQ MXRA8	6.14e-04	177	42	3	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEC ZAP70 MBP	6.14e-04	177	42	3	f1efd9c3074d5635700fe7fbebf3dd0b1e0a84f1
ToppCell	COPD-Epithelial-Aberrant_Basaloid\|World / Disease state, Lineage and Cell class	SOX11 ITGA2 DSP	6.14e-04	177	42	3	22b7cda748cf5e665be54ca5bae89f0c130d5e7f
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAM3B DSP EPHA8	6.14e-04	177	42	3	c80893e5cf5688ee9f5afc8f11b3890f296c9e1f
ToppCell	facs-Marrow-T-cells-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA2 TEC MOCOS	6.24e-04	178	42	3	41745a589567ca5ea6d06331f4c8da03595b5f5c
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-GHRL+_NE_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FAM3B DSP EPHA8	6.24e-04	178	42	3	32cc4155267baf1b536a61310044e6502d09531f
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT-iNKT/MAIT\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEC ZAP70 MBP	6.24e-04	178	42	3	7905621f5b2aa55324c5592d1d2fef763a5fa41f
ToppCell	facs-Heart-RA-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM3B THRAP3 MBP	6.24e-04	178	42	3	b505e2550860e777535ee95f29c936242fd607f1
ToppCell	facs-Marrow-T-cells-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA2 TEC MOCOS	6.24e-04	178	42	3	eb940dd64c973f68bcaad6069d3bd56383329db5
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEC ZAP70 MBP	6.24e-04	178	42	3	f914092c20130207193f97c6044ae61a9a440a86
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDX3Y TEC DHX9	6.34e-04	179	42	3	7c8a2fa1326c73dc9e774df645b572864fd97133
ToppCell	LPS-antiTNF-Lymphocytic_NKT\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEC ZAP70 MBP	6.34e-04	179	42	3	ecea75c568911ff56939c9f67ab901497bd4356c
ToppCell	LPS-IL1RA-Lymphocytic_NKT\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEC ZAP70 MBP	6.34e-04	179	42	3	5ccf0824611ded5c673d94dff3048aedac12f1a8
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX11 COL6A1 MXRA8	6.45e-04	180	42	3	935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell	5'-Airway_Nasal-Mesenchymal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX11 COL6A1 MXRA8	6.45e-04	180	42	3	3dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCell	AT1-AT2_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	SOX11 ITGA2 MXRA8	6.45e-04	180	42	3	3c7b2033821f9e34e2924bd8655f566edcbcc7d3
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDX3Y TEC DHX9	6.45e-04	180	42	3	8bf6e8b6b45ce42f8c5f23e7cd1752ec8b3fa2d2
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_NK-NK_bright-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ABHD17A ZAP70 MBP	6.55e-04	181	42	3	4795833e0ec49287bd7809ecfe523fc527565fba
ToppCell	-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	GATA4 COL6A1 BCAN	6.55e-04	181	42	3	ef579e958f334da0f9415aa7e3d5c02c807954a6
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_NK-NK_bright\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ABHD17A ZAP70 MBP	6.55e-04	181	42	3	208cdccc2f0d0f2d8ec321064c63aed206d46c32
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 FAM3B MXRA8	6.55e-04	181	42	3	c26d3cbbc592299786d79d1b15fc6bead2aafb9a
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA2 ZAP70 DHX9	6.66e-04	182	42	3	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABHD17A ZAP70 MBP	6.66e-04	182	42	3	feda21c92d30848de70c8b404eaabbca3f5e894d
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ITGA2 ZAP70 SETBP1	6.66e-04	182	42	3	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	Control-Epithelial-Basal\|Control / Disease state, Lineage and Cell class	ITGA2 DSP PTPRQ	6.66e-04	182	42	3	caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA2 ZAP70 DHX9	6.66e-04	182	42	3	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	severe_influenza-gd_T\|severe_influenza / disease group, cell group and cell class (v2)	CIRBP ABHD17A ZAP70	6.66e-04	182	42	3	b6b44c90af3f0c0dddb2b171087865d8c15a3973
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX11 COL6A1 MXRA8	6.76e-04	183	42	3	6d98973098c6d20c5305bce6a83a549a7d8dbfba
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX11 COL6A1 MXRA8	6.76e-04	183	42	3	cc7f5a17b40e8d901885174922e5fa8877643071
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMK+-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	DDX3Y MBP EPHA8	6.76e-04	183	42	3	79defd22b3194dad16db55b9bdd220c09c1e6b90
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DSP MOCOS PTPRQ	6.76e-04	183	42	3	ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	PARP11 DSP PARP12	6.76e-04	183	42	3	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	Control-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEC ZAP70 MBP	6.76e-04	183	42	3	2c5707ada3442eb7100a2a5f9438d5a2ac53a9e1
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX11 COL6A1 MXRA8	6.76e-04	183	42	3	803376f5260de83c48d4f7301278d078a32b3e6e
ToppCell	(7)_Epithelial-H_(AT1)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	FAM3B ITGA2 DSP	6.87e-04	184	42	3	1f76b37c265b519171b767a52d48f31f0cdc4a3c
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX11 ZNF577 SETBP1	6.87e-04	184	42	3	cd2919dc8e90d03f57eb43f59f7da9bcd676496e
ToppCell	tumor_Lung-Fibroblasts-Mesothelial_cells\|tumor_Lung / Location, Cell class and cell subclass	GATA4 INHA PTPRQ	6.87e-04	184	42	3	b0a251030d127858e68cf164be158f209a4d720f
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCAF11 THRAP3 DHX9	6.87e-04	184	42	3	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D122\|Adult / Lineage, Cell type, age group and donor	COL6A1 SETBP1 MXRA8	6.87e-04	184	42	3	2b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 SETBP1 FARP2	6.87e-04	184	42	3	42cadfdb5d29a50bd7e901ddd14d42b39e8474f0
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMH+-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ABHD17A DDX3Y MBP	6.98e-04	185	42	3	097d628f92e13250c15b550f2fd1f4225fc07558
Disease	tyrosine-protein kinase TEC measurement	TEC TEC	1.02e-05	4	39	2	EFO_0020830
Disease	cystathionine measurement	TEC TEC	2.87e-04	19	39	2	EFO_0010474
Disease	myositis	TEC TEC	1.22e-03	39	39	2	EFO_0000783
Disease	rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement	SCAF11 TEC TEC	1.47e-03	170	39	3	EFO_0000685, EFO_0007791, EFO_0007837

Protein segments in the cluster

Peptide	Gene	Start	Entry
DSDGELGSRYSSGYS	FAM219B	126	Q5XKK7
DYSGYGASSGRPSER	ABHD17A	146	Q96GS6
CGDYYIGGRRFSSLS	RASA1	236	P20936
YREGSARYAFSFSGA	BCAN	161	Q96GW7
TYDDRAYSSFGGGRG	EIF4H	6	Q15056
SGGSTYYADSRKGRF	IGHV3-38	71	A0A0C4DH36
SGGSTYYADSRKGRF	IGHV3-38-3	71	P0DTE1
FGRRSSYGGSSYGNS	HMBOX1	61	Q6NT76
FRKSGATCGRSDTYY	MBD1	21	Q9UIS9
RKTYFGGGTASAYLA	MOCOS	286	Q96EN8
YRKSAGGFIHGFRYT	FOXRED2	391	Q8IWF2
SDTYAYRLLSGGGRS	FAM3B	71	P58499
KYAYSAASGGRRSAT	ITGA2	261	P17301
YSAYVTASTRFGDGK	PTPRQ	961	Q9UMZ3
VHGTSYGKGSYFARD	PARP12	586	Q9H0J9
FGKGTYFARDAAYSS	PARP11	231	Q9NR21
REQYGRAGFAGSYSS	GATA4	146	P43694
GYVTRFYREASSGAA	COL6A1	921	P12109
TSGGGGTSRMYYSRR	DSP	31	P15924
RRGSFDATGNSSYSY	DSP	2846	P15924
RYRDHFAAGGYSSLG	EPHA8	946	P29322
YGGRASDYKSAHKGF	MBP	261	P02686
RTTSDGGYSFKYETV	INHA	341	P05111
SFGSRDSRGKPGYFS	DDX3Y	71	O15523
KAVFFSRGSSFRYSG	FARP2	331	O94887
GNRGRGTYRSSFAYK	SCAF11	1076	Q99590
RYDNGSGYRRGGSSY	DHX9	1166	Q08211
YSGGSTYYADSVKGR	IGHV3-53	71	P01767
ATSGAGGGSRLYYSF	SOX11	301	P35716
SGRSGYGYRRSGRDK	SRSF4	81	Q08170
YTKFGGEGSSGFRHY	TEC	286	P42680
RESRYGGSHYSSSGY	SRSF8	181	Q9BRL6
GGRDSYSSSYGRSDR	RBMXL2	321	O75526
RSGGYGGSRDYYSSR	CIRBP	131	Q14011
LGADDSYYTARSAGK	ZAP70	486	P43403
SAASGGAAYTKRYLE	THRAP3	336	Q9Y2W1
YTYSSGNKEDGRFTA	TRAV12-3	71	A0A0B4J271
SFSNSYGRSDHYGRG	RBMXL3	896	Q8N7X1
SSIKSYGLSDRYGGG	RBMXL3	966	Q8N7X1
RRYAGKDSDAFGGYG	ZNF577	101	Q9BSK1
RSSYSGYSGYSQGSR	SCN8A	611	Q9UQD0
GYSGYSQGSRSSRIF	SCN8A	616	Q9UQD0
TKTNDYGYCSGGSRS	VN1R3	161	Q9BXE9
SGSKRRSYEGFGTYR	SETBP1	1296	Q9Y6X0
SRFGGSYGGRFESSY	ZNF326	101	Q5BKZ1
SYGGRFESSYRNSLD	ZNF326	106	Q5BKZ1
RRGGYEYSDQKSGKS	MXRA8	366	Q9BRK3