Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR2 RYR3

2.03e-074753GO:0005219
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

TPCN2 RYR1 RYR2 RYR3

5.40e-0718754GO:0015278
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR2 RYR3

1.01e-066753GO:0048763
GeneOntologyMolecularFunctionligand-gated calcium channel activity

TPCN2 RYR1 RYR2 RYR3

5.35e-0631754GO:0099604
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

TPCN2 RYR1 RYR2 RYR3

6.92e-0633754GO:0005217
GeneOntologyMolecularFunctioncalcium channel activity

TPCN2 ORAI3 RYR1 RYR2 RYR3

1.25e-04129755GO:0005262
GeneOntologyMolecularFunctionreceptor signaling protein tyrosine kinase activator activity

LTK ALK

1.38e-045752GO:0030298
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TPCN2 ORAI3 RYR1 RYR2 RYR3

2.61e-04151755GO:0015085
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TPCN2 KCNC3 KCNC4 ORAI3 RYR1 RYR2 RYR3

3.03e-04343757GO:0005261
GeneOntologyMolecularFunctiongated channel activity

TPCN2 KCNC3 KCNC4 RYR1 RYR2 RYR3

1.60e-03334756GO:0022836
GeneOntologyMolecularFunctionmonoatomic ion channel activity

TPCN2 KCNC3 KCNC4 ORAI3 RYR1 RYR2 RYR3

1.67e-03459757GO:0005216
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TPCN2 KCNC3 KCNC4 ORAI3 RYR1 RYR2 RYR3

1.80e-03465757GO:0046873
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

LTK ALK EPHA8

1.88e-0365753GO:0004714
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

TPCN2 RYR1 RYR2 RYR3

1.91e-03140754GO:0099094
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

TPCN2 KCNC3 KCNC4 RYR1

2.58e-03152754GO:0022843
GeneOntologyMolecularFunctionHMG box domain binding

POU3F2 POU5F1B

3.35e-0323752GO:0071837
GeneOntologyMolecularFunctionglutamate receptor binding

SHANK1 SHISA7 PRNP

3.52e-0381753GO:0035254
GeneOntologyMolecularFunctionchannel activity

TPCN2 KCNC3 KCNC4 ORAI3 RYR1 RYR2 RYR3

3.54e-03525757GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

TPCN2 KCNC3 KCNC4 ORAI3 RYR1 RYR2 RYR3

3.58e-03526757GO:0022803
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

LTK ALK EPHA8

4.03e-0385753GO:0019199
GeneOntologyBiologicalProcesscellular response to caffeine

RYR1 RYR2 RYR3

6.32e-0611713GO:0071313
GeneOntologyBiologicalProcesscellular response to purine-containing compound

RYR1 RYR2 RYR3

1.38e-0514713GO:0071415
GeneOntologyBiologicalProcessresponse to caffeine

RYR1 RYR2 RYR3

4.97e-0521713GO:0031000
GeneOntologyCellularComponentmonoatomic ion channel complex

TPCN2 KCNC3 KCNC4 SHISA7 RYR1 RYR2 RYR3

3.50e-04378737GO:0034702
GeneOntologyCellularComponentjunctional membrane complex

RYR1 RYR3

4.26e-049732GO:0030314
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

RYR1 RYR2 RYR3

5.22e-0445733GO:0033017
GeneOntologyCellularComponentjunctional sarcoplasmic reticulum membrane

RYR1 RYR2

5.32e-0410732GO:0014701
GeneOntologyCellularComponentsmooth endoplasmic reticulum

RYR1 RYR2 RYR3

5.57e-0446733GO:0005790
GeneOntologyCellularComponentdendrite membrane

KCNC3 KCNC4 SHISA7

9.92e-0456733GO:0032590
GeneOntologyCellularComponentcation channel complex

KCNC3 KCNC4 RYR1 RYR2 RYR3

1.39e-03235735GO:0034703
GeneOntologyCellularComponentdendritic spine membrane

KCNC3 SHISA7

1.77e-0318732GO:0032591
GeneOntologyCellularComponentcalcium channel complex

RYR1 RYR2 RYR3

2.13e-0373733GO:0034704
GeneOntologyCellularComponenttransmembrane transporter complex

TPCN2 KCNC3 KCNC4 SHISA7 RYR1 RYR2 RYR3

2.31e-03523737GO:1902495
GeneOntologyCellularComponentdendrite

SHANK1 GLRX5 KCNC3 KCNC4 SARM1 SHISA7 RGS12 PRNP EPHA8

2.93e-03858739GO:0030425
GeneOntologyCellularComponentneuron projection membrane

KCNC3 KCNC4 SHISA7

2.97e-0382733GO:0032589
GeneOntologyCellularComponentdendritic tree

SHANK1 GLRX5 KCNC3 KCNC4 SARM1 SHISA7 RGS12 PRNP EPHA8

2.97e-03860739GO:0097447
GeneOntologyCellularComponenttransporter complex

TPCN2 KCNC3 KCNC4 SHISA7 RYR1 RYR2 RYR3

3.06e-03550737GO:1990351
GeneOntologyCellularComponentsarcoplasmic reticulum

RYR1 RYR2 RYR3

3.63e-0388733GO:0016529
DomainRyanrecept_TM4-6

RYR1 RYR2 RYR3

5.04e-083703IPR009460
DomainRyR

RYR1 RYR2 RYR3

5.04e-083703PF02026
DomainRyanodine_rcpt

RYR1 RYR2 RYR3

5.04e-083703IPR003032
DomainRR_TM4-6

RYR1 RYR2 RYR3

5.04e-083703PF06459
DomainRyan_recept

RYR1 RYR2 RYR3

5.04e-083703IPR013333
DomainRIH_assoc

RYR1 RYR2 RYR3

1.00e-066703PF08454
DomainRIH_assoc-dom

RYR1 RYR2 RYR3

1.00e-066703IPR013662
DomainRIH_dom

RYR1 RYR2 RYR3

1.00e-066703IPR000699
DomainIns145_P3_rcpt

RYR1 RYR2 RYR3

1.00e-066703IPR014821
DomainRyanodine_recept-rel

RYR1 RYR2 RYR3

1.00e-066703IPR015925
Domain-

RYR1 RYR2 RYR3

1.00e-0667031.25.10.30
DomainRYDR_ITPR

RYR1 RYR2 RYR3

1.00e-066703PF01365
DomainIns145_P3_rec

RYR1 RYR2 RYR3

1.00e-066703PF08709
DomainIon_trans_dom

TPCN2 KCNC3 KCNC4 RYR1 RYR2 RYR3

4.32e-06114706IPR005821
DomainIon_trans

TPCN2 KCNC3 KCNC4 RYR1 RYR2 RYR3

4.32e-06114706PF00520
DomainMIR

RYR1 RYR2 RYR3

5.94e-0610703PS50919
DomainMIR

RYR1 RYR2 RYR3

5.94e-0610703PF02815
DomainMIR

RYR1 RYR2 RYR3

5.94e-0610703SM00472
DomainMIR_motif

RYR1 RYR2 RYR3

5.94e-0610703IPR016093
DomainPotassium_chann

KCNC3 KCNC4

1.38e-052702PF11404
DomainK_chnl_volt-dep_Kv3_ID

KCNC3 KCNC4

1.38e-052702IPR021105
DomainPOU

POU3F1 POU3F2 POU5F1B

2.73e-0516703SM00352
DomainPOU_2

POU3F1 POU3F2 POU5F1B

2.73e-0516703PS00465
DomainPOU_dom

POU3F1 POU3F2 POU5F1B

2.73e-0516703IPR000327
DomainPOU_3

POU3F1 POU3F2 POU5F1B

2.73e-0516703PS51179
DomainPou

POU3F1 POU3F2 POU5F1B

2.73e-0516703PF00157
DomainPOU_1

POU3F1 POU3F2 POU5F1B

2.73e-0516703PS00035
DomainPOU

POU3F1 POU3F2 POU5F1B

3.30e-0517703IPR013847
DomainK_chnl_volt-dep_Kv3

KCNC3 KCNC4

8.27e-054702IPR003974
DomainTF_POU_3

POU3F1 POU3F2

8.27e-054702IPR016362
Domain-

POU3F1 POU3F2 POU5F1B

1.38e-04277031.10.260.40
DomainLambda_DNA-bd_dom

POU3F1 POU3F2 POU5F1B

1.72e-0429703IPR010982
DomainHomeodomain-like

PHOX2A HOXD11 LONRF1 POU3F1 POU3F2 TIGD5 POU5F1B

2.42e-04332707IPR009057
DomainTyrKc

MAP3K11 LTK ALK EPHA8

3.33e-0488704SM00219
DomainTyr_kinase_cat_dom

MAP3K11 LTK ALK EPHA8

3.33e-0488704IPR020635
DomainHomeobox_CS

PHOX2A HOXD11 POU3F1 POU3F2 POU5F1B

6.65e-04186705IPR017970
Domain-

PHOX2A HOXD11 POU3F1 POU3F2 TIGD5 POU5F1B

6.68e-042837061.10.10.60
DomainTyr_kinase_rcpt_2_CS

LTK ALK

7.45e-0411702IPR002011
DomainRECEPTOR_TYR_KIN_II

LTK ALK

8.92e-0412702PS00239
DomainBTB_2

KCNC3 KCNC4 KCTD17

1.03e-0353703PF02214
DomainT1-type_BTB

KCNC3 KCNC4 KCTD17

1.03e-0353703IPR003131
DomainPLAC

THSD4 ADAMTS19

1.22e-0314702PF08686
DomainChannel_four-helix_dom

TPCN2 KCNC3 KCNC4

1.28e-0357703IPR027359
Domain-

TPCN2 KCNC3 KCNC4

1.28e-03577031.20.120.350
DomainPkinase_Tyr

MAP3K11 LTK ALK EPHA8

1.40e-03129704PF07714
DomainSer-Thr/Tyr_kinase_cat_dom

MAP3K11 LTK ALK EPHA8

1.79e-03138704IPR001245
DomainHomeobox

PHOX2A HOXD11 POU3F1 POU3F2 POU5F1B

1.85e-03234705PF00046
DomainHOMEOBOX_1

PHOX2A HOXD11 POU3F1 POU3F2 POU5F1B

1.92e-03236705PS00027
DomainHOX

PHOX2A HOXD11 POU3F1 POU3F2 POU5F1B

1.95e-03237705SM00389
DomainHOMEOBOX_2

PHOX2A HOXD11 POU3F1 POU3F2 POU5F1B

2.03e-03239705PS50071
DomainHomeobox_dom

PHOX2A HOXD11 POU3F1 POU3F2 POU5F1B

2.03e-03239705IPR001356
DomainPLAC

THSD4 ADAMTS19

2.27e-0319702PS50900
DomainPLAC

THSD4 ADAMTS19

2.27e-0319702IPR010909
DomainADAM_spacer1

THSD4 ADAMTS19

3.33e-0323702IPR010294
DomainADAM_spacer1

THSD4 ADAMTS19

3.33e-0323702PF05986
DomainSPRY

RYR1 RYR2 RYR3

4.27e-0387703SM00449
DomainSAM

SHANK1 SARM1 EPHA8

4.41e-0388703SM00454
DomainK_chnl_volt-dep_Kv

KCNC3 KCNC4

4.57e-0327702IPR003968
DomainSPRY

RYR1 RYR2 RYR3

5.30e-0394703PF00622
DomainSPRY_dom

RYR1 RYR2 RYR3

5.30e-0394703IPR003877
DomainB30.2/SPRY

RYR1 RYR2 RYR3

5.46e-0395703IPR001870
DomainB302_SPRY

RYR1 RYR2 RYR3

5.46e-0395703PS50188
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

PRNP RYR1 RYR2 RYR3

3.71e-0719464M47760
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

RYR1 RYR2 RYR3

5.27e-0611463M47958
PathwayWP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING

RYR1 RYR2 RYR3

9.09e-0613463M39589
PathwayWP_15Q25_COPY_NUMBER_VARIATION

SHANK1 ALPK3 RYR1 RYR2

1.46e-0546464M48105
PathwayREACTOME_STIMULI_SENSING_CHANNELS

TPCN2 RYR1 RYR2 RYR3

2.98e-0499464MM14910
PathwayREACTOME_STIMULI_SENSING_CHANNELS

TPCN2 RYR1 RYR2 RYR3

3.87e-04106464M27200
PathwayREACTOME_ION_HOMEOSTASIS

RYR1 RYR2 RYR3

7.18e-0454463MM15202
PathwayREACTOME_ION_HOMEOSTASIS

RYR1 RYR2 RYR3

7.18e-0454463M27460
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR2 RYR3

1.04e-08377318403125
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR1 RYR2 RYR3

1.04e-08377318434746
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR1 RYR2 RYR3

1.04e-0837739204703
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR1 RYR2 RYR3

1.04e-0837737876312
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR1 RYR2 RYR3

1.04e-08377321881589
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR1 RYR2 RYR3

1.04e-08377312213830
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR1 RYR2 RYR3

1.04e-0837739242641
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR1 RYR2 RYR3

1.04e-08377322948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR1 RYR2 RYR3

1.04e-08377310788707
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR1 RYR2 RYR3

1.04e-08377325239916
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR1 RYR2 RYR3

1.04e-0837737621815
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR1 RYR2 RYR3

1.04e-08377318643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR1 RYR2 RYR3

1.04e-08377311159936
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR1 RYR2 RYR3

1.04e-08377310473538
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR1 RYR2 RYR3

1.04e-0837737959768
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR1 RYR2 RYR3

1.04e-0837734600883
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR1 RYR2 RYR3

1.04e-0837737635066
Pubmed

A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.

RYR1 RYR2 RYR3

4.17e-08477318206662
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR1 RYR2 RYR3

4.17e-08477323413940
Pubmed

Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.

RYR1 RYR2 RYR3

4.17e-0847739384575
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR1 RYR2 RYR3

4.17e-0847739607712
Pubmed

Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.

RYR1 RYR2 RYR3

4.17e-08477323482488
Pubmed

Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.

RYR1 RYR2 RYR3

1.04e-07577323918386
Pubmed

Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.

RYR1 RYR2 RYR3

1.04e-07577319011160
Pubmed

Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.

RYR1 RYR2 RYR3

2.08e-07677319549818
Pubmed

Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

RYR1 RYR2 RYR3

2.08e-07677326025922
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR1 RYR2 RYR3

2.08e-07677323463619
Pubmed

FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.

RYR1 RYR2 RYR3

2.08e-07677314592808
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR1 RYR2 RYR3

2.08e-07677320519450
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR1 RYR2 RYR3

2.08e-07677325966694
Pubmed

HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.

RYR1 RYR2 RYR3

2.08e-07677319009018
Pubmed

The Pou5f1/Pou3f-dependent but SoxB-independent regulation of conserved enhancer N2 initiates Sox2 expression during epiblast to neural plate stages in vertebrates.

POU3F1 POU3F2 POU5F1B

2.08e-07677321185279
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR1 RYR2 RYR3

2.08e-07677316844763
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR1 RYR2 RYR3

3.63e-07777311860456
Pubmed

Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.

RYR1 RYR2 RYR3

3.63e-07777320962236
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR1 RYR2 RYR3

5.80e-07877319033399
Pubmed

ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.

TPCN2 RYR1 RYR3

5.80e-07877330563862
Pubmed

Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.

RYR1 RYR2 RYR3

5.80e-07877311784029
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

RYR1 RYR2 RYR3

2.26e-061277319095005
Pubmed

Kv3 voltage-gated potassium channels regulate neurotransmitter release from mouse motor nerve terminals.

KCNC3 KCNC4

4.84e-06277215610163
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

4.84e-06277221531043
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

4.84e-06277216678258
Pubmed

Principal mutation hotspot for central core disease and related myopathies in the C-terminal transmembrane region of the RYR1 gene.

RYR1 RYR3

4.84e-06277212565913
Pubmed

Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.

RYR1 RYR3

4.84e-0627729489997
Pubmed

Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.

RYR1 RYR2

4.84e-06277217259277
Pubmed

Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.

RYR1 RYR3

4.84e-0627729192302
Pubmed

The block of ryanodine receptors selectively inhibits fetal myoblast differentiation.

RYR1 RYR3

4.84e-06277212640042
Pubmed

Ryanodine receptor oligomeric interaction: identification of a putative binding region.

RYR1 RYR2

4.84e-06277214722100
Pubmed

Structural and functional interactions within ryanodine receptor.

RYR1 RYR2

4.84e-06277226009179
Pubmed

Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.

RYR1 RYR3

4.84e-0627727556644
Pubmed

Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.

RYR1 RYR2

4.84e-06277232899693
Pubmed

Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion.

RYR1 RYR3

4.84e-06277214592949
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

4.84e-0627728898078
Pubmed

Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.

RYR1 RYR3

4.84e-06277215894801
Pubmed

Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.

RYR1 RYR2

4.84e-06277230542613
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

4.84e-06277214550562
Pubmed

Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.

RYR1 RYR2

4.84e-06277215280431
Pubmed

Expression of the ryanodine receptor isoforms in immune cells.

RYR1 RYR2

4.84e-06277211673493
Pubmed

B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.

RYR1 RYR2

4.84e-06277211673462
Pubmed

Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.

RYR1 RYR3

4.84e-0627729799464
Pubmed

Effect of calmodulin on Ca2+-induced Ca2+ release of skeletal muscle from mutant mice expressing either ryanodine receptor type 1 or type 3.

RYR1 RYR3

4.84e-0627729817784
Pubmed

Anaplastic lymphoma kinase and leukocyte tyrosine kinase: functions and genetic interactions in learning, memory and adult neurogenesis.

LTK ALK

4.84e-06277222079349
Pubmed

Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.

RYR1 RYR2

4.84e-06277225370123
Pubmed

Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.

RYR2 RYR3

4.84e-06277214985349
Pubmed

Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.

RYR1 RYR2

4.84e-06277215033925
Pubmed

Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.

RYR1 RYR2

4.84e-06277218618700
Pubmed

Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.

RYR1 RYR3

4.84e-06277217118445
Pubmed

RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle.

RYR1 RYR3

4.84e-06277211500519
Pubmed

Abnormal development of the locus coeruleus in Ear2(Nr2f6)-deficient mice impairs the functionality of the forebrain clock and affects nociception.

NR2F6 PHOX2A RFLNB

8.31e-061877315741322
Pubmed

Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor.

RYR1 RYR3

1.45e-05377211171121
Pubmed

Differential alterations in expressions of ryanodine receptor subtypes in cerebellar cortical neurons of an ataxic mutant, rolling mouse Nagoya.

RYR1 RYR3

1.45e-05377218313230
Pubmed

Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.

RYR2 RYR3

1.45e-05377229730765
Pubmed

Genomic organization, nucleotide sequence, and cellular distribution of a Shaw-related potassium channel gene, Kv3.3, and mapping of Kv3.3 and Kv3.4 to human chromosomes 19 and 1.

KCNC3 KCNC4

1.45e-0537721740329
Pubmed

Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells.

RYR1 RYR2

1.45e-05377224123915
Pubmed

Dopamine D1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence.

RYR1 RYR2

1.45e-05377223278119
Pubmed

Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons.

RYR1 RYR2

1.45e-05377223454728
Pubmed

Oct4 expression is not required for mouse somatic stem cell self-renewal.

POU3F1 POU5F1B

1.45e-05377218159219
Pubmed

RYR2 proteins contribute to the formation of Ca(2+) sparks in smooth muscle.

RYR2 RYR3

1.45e-05377215024040
Pubmed

Identification of a biologically active fragment of ALK and LTK-Ligand 2 (augmentor-α).

LTK ALK

1.45e-05377230061385
Pubmed

Intracellular calcium release channel expression during embryogenesis.

RYR1 RYR2

1.45e-0537729986730
Pubmed

Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells.

POU3F1 POU3F2 POU5F1B

2.62e-052677322992956
Pubmed

Characterization of the binding sites for the interactions between FKBP12 and intracellular calcium release channels.

RYR1 RYR3

2.89e-05477222100703
Pubmed

Increase of ryanodine receptors by dopamine D1 receptors is negatively regulated by γ-aminobutyric acid type B receptors in primary cultures of mouse cerebral cortical neurons.

RYR1 RYR2

2.89e-05477222504960
Pubmed

Brain expression of Kv3 subunits during development, adulthood and aging and in a murine model of Alzheimer's disease.

KCNC3 KCNC4

2.89e-05477221912965
Pubmed

Gbx2 directly restricts Otx2 expression to forebrain and midbrain, competing with class III POU factors.

POU3F1 POU3F2

2.89e-05477222566684
Pubmed

Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand-receptor interactions.

LTK ALK

2.89e-05477226630010
Pubmed

A POU factor binding site upstream of the Chx10 homeobox gene is required for Chx10 expression in subsets of retinal progenitor cells and bipolar cells.

POU3F1 POU3F2

2.89e-05477215893976
Pubmed

Structural basis of cytokine-mediated activation of ALK family receptors.

LTK ALK

2.89e-05477234646012
Pubmed

Calmodulin modulates the termination threshold for cardiac ryanodine receptor-mediated Ca2+ release.

RYR1 RYR2

2.89e-05477223992453
Pubmed

Structure and evolution of four POU domain genes expressed in mouse brain.

POU3F1 POU3F2

2.89e-0547721565620
Pubmed

FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase.

LTK ALK

2.89e-05477226418745
Pubmed

S100A1 Protein Does Not Compete with Calmodulin for Ryanodine Receptor Binding but Structurally Alters the Ryanodine Receptor·Calmodulin Complex.

RYR1 RYR2

2.89e-05477227226555
Pubmed

Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.

RYR1 RYR2

2.89e-05477219120137
Pubmed

FKBP binding characteristics of cardiac microsomes from diverse vertebrates.

RYR1 RYR2

2.89e-05477211237759
Pubmed

SOX2 co-occupies distal enhancer elements with distinct POU factors in ESCs and NPCs to specify cell state.

POU3F2 POU5F1B

2.89e-05477223437007
Pubmed

Selective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells.

POU3F1 POU3F2

2.89e-05477226265007
Pubmed

Rhombomere-specific analysis reveals the repertoire of genetic cues expressed across the developing hindbrain.

NR2F6 FAM117A ZNF503

2.94e-052777319208226
Pubmed

The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U.

POU3F1 POU3F2

4.82e-0557729105675
Pubmed

Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.

RYR2 RYR3

4.82e-05577233060591
Pubmed

POU family transcription factors in the nervous system.

POU3F1 POU5F1B

4.82e-05577210199551
Cytoband16p11.2

ASPHD1 NFATC2IP ORAI3 ZNF646

3.10e-0419177416p11.2
CytobandEnsembl 112 genes in cytogenetic band chr19q13

SHANK1 CAPN12 PRR12 KCNC3 FIZ1 SHISA7 RYR1 SPRED3

8.71e-041192778chr19q13
CytobandEnsembl 112 genes in cytogenetic band chr16p11

ASPHD1 NFATC2IP ORAI3 ZNF646

1.26e-03278774chr16p11
Cytoband19p13.1

NR2F6 HAPLN4

2.98e-034877219p13.1
Cytoband1q43

OPN3 RYR2

3.36e-03517721q43
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR2 RYR3

1.44e-083453287
GeneFamilyPOU class homeoboxes and pseudogenes

POU3F1 POU3F2 POU5F1B

2.46e-0523453523
GeneFamilySterile alpha motif domain containing

SHANK1 SARM1 EPHA8

1.36e-0388453760
GeneFamilyPotassium voltage-gated channels

KCNC3 KCNC4

4.45e-0340452274
GeneFamilyReceptor Tyrosine Kinases|CD molecules

LTK ALK

4.45e-0340452321
GeneFamilyPDZ domain containing

SHANK1 TAMALIN RGS12

6.38e-031524531220
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

TRA2B OPN3 RYR1

1.03e-02181453694
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHANK1 INSC TIGD5 RYR2 RYR3

3.36e-0613277502491930097b75aaeedab9e8200711b0dc610944
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

SHANK1 RELL2 HAPLN4 LTK EPHA8

1.06e-051677759efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

SHANK1 RELL2 HAPLN4 LTK EPHA8

1.06e-05167775904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 PHOX2A KCNC3 RELL2 EPHA8

1.18e-0517177599176a932569fa1c7e1c01009684f5a65244b96e
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|343B / Donor, Lineage, Cell class and subclass (all cells)

MED14OS POU3F1 PRNP RYR1 ZNF513

1.48e-05179775c09c3eed43d1aa3b7aa8f3021e6f2737840cde16
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEMP1 KCNC3 INSC HAPLN4 KANK4

1.52e-05180775da723df348d7b8449bb1124f23fe6fa706412adb
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 KCNC4 RELL2 HAPLN4 EPHA8

1.52e-051807753d54cc767e25d91ed2203d8a03e5bf5e15f21699
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEMP1 KCNC3 INSC HAPLN4 KANK4

1.52e-051807755b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEMP1 KCNC3 INSC HAPLN4 KANK4

1.52e-0518077550758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCellGlobus_pallidus-Neuronal-Inhibitory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KCNC4 RELL2 SARM1 HAPLN4 ALK

1.60e-0518277504ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 RFLNB CCM2L TAMALIN RYR2

1.64e-05183775dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHANK1 THSD4 INSC ATRNL1 RYR2

1.64e-051837757eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 RFLNB CCM2L TAMALIN RYR2

1.64e-051837754759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MED14OS POU3F1 PRNP RYR1 ZNF513

1.78e-05186775bca5215d406f1785bf3a420201d5686071fcaca5
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 FAM117A SMOX RYR1

2.34e-05967747a1a27d996c2bbcd922da524969f568f0575dfad
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

GDF7 KIF26A ATRNL1 C11orf96 RYR2

2.52e-0520077516a3685c41194a0a4a772e4eee372160263480e0
ToppCellMild/Remission-B_intermediate-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MED14OS TRIR KANK4 POU3F2

6.17e-0512377469b7f2f4604bf221a0ff581c51de743e8a4c0537
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic-3|TCGA-Mesothelium / Sample_Type by Project: Shred V9

ADAMTS19 HOXD11 HAPLN4 SHISA7

6.99e-05127774df2854bcb2708ddc13b3ca48c03887380e827790
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Striatum / BrainAtlas - Mouse McCarroll V32

SHANK1 OPN3 HAPLN4 EPHA8

8.36e-05133774d5326a6ccada5ae6d3e8f7d4a858c90050e23c5b
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NR2F6 GLRX5 SMOX RYR2

9.11e-05136774a2063abe2d7c3277bfbe1514c8c66363cf04b248
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_stem_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SHANK1 SARM1 POU3F1 POU3F2

9.37e-05137774ed81624b9167255ce88dcf6ad7f1636376ea0525
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_stem_cell-Mesenchymal_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SHANK1 SARM1 POU3F1 POU3F2

9.37e-0513777447859aa25f32367461c1ec75ed9060bee430c6b7
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_8|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

C11orf96 TUSC1 KCTD17 ZNF503

1.05e-04141774737237db115721524c44ea4c55aed000e1b00ee5
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_8|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

C11orf96 TUSC1 KCTD17 ZNF503

1.05e-04141774c14f84bc3921cafbce6fa7f7163ecf3cd9cdf073
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Macc1_Lrg1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RFLNB POU3F1 TAMALIN RYR1

1.08e-04142774d08e1880425d285c4433014fe0242ac7ff7734af
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD4 MARCHF9 MPLKIP ARMCX4

1.11e-04143774b4ed3855652fdf32f97cb7c18cab4f4f4c24d5c7
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

POU3F1 LTK RYR1 EPHA8

1.11e-041437745fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

POU3F1 RYR1 RYR3 EPHA8

1.14e-0414477408005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS19 ATRNL1 ALK RYR2

1.58e-04157774bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCellfacs-Marrow-B-cells-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLRX5 FAM117A SMOX PRNP

1.87e-0416477418eeda51e69722992c3a7f699be293535a90868b
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNC3 ALK VARS1 RYR1

1.92e-0416577436415924d05373e9dd3665be599f4f3f40bf0497
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNC3 ALK VARS1 RYR1

1.92e-0416577456310fddd3d8e4afdfde066d26cee9747e5b8c6a
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-red_blood_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLRX5 FAM117A HAPLN4 SMOX

1.92e-0416577462dd54dfbec7f43a41546a1fec719545c2608a36
ToppCellICU-NoSEP-Lymphocyte-T_NK-NK_CD56bright|ICU-NoSEP / Disease, Lineage and Cell Type

CAPN12 NEMP1 FAM117A TUSC1

2.01e-04167774f4f188a8efca8cdd0ecfb857fe4538c10847eadd
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

CCM2L KIF26A TAMALIN RYR3

2.05e-041687748c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 LONRF1 SARM1 RYR1

2.15e-041707748e774af244cfe787fa0ea2b6be0c3c2d00bfe4fc
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 LONRF1 SARM1 RYR1

2.15e-04170774f5140eb9313c0d1bb31f8a761d9c062c56733a61
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN12 NR2F6 RYR1 OPLAH

2.20e-04171774e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-MAIT|Multiple_Sclerosis / Disease, Lineage and Cell Type

CAPN12 LTK PDCD4 PRNP

2.25e-0417277418bda0038cb37da6784e7bf7291272c108cfd9c5
ToppCellnormal_Lung-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

ASPHD1 KCNC3 RGS12 RYR2

2.35e-04174774e324320b52c904496e26fcecfa179b3431729ec0
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLRX5 FAM117A HAPLN4 SMOX

2.45e-04176774fc51e4dcad5456c229d76fdcb9a80c4c79eacf3f
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INSC ALPK3 KANK4 PRNP

2.56e-041787745cf12927f0756c4d8a289fe4308d736382e6212e
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MARCHF9 SMOX TAMALIN ZNF503

2.61e-04179774163f5430d72ea0c1b239ea5d21e53be536636d3d
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MARCHF9 SMOX TAMALIN ZNF503

2.61e-041797740624dd537a68736f4d7b8b4de2c56168ed0e60a9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

C11orf96 HAPLN4 POU3F1 PRNP

2.67e-04180774ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A TSPO TAMALIN RGS12

2.67e-041807742405aa5699a8d8cf4c6b3dca07510e774728ac50
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A TSPO TAMALIN RGS12

2.67e-041807749c47852c0a723e2f5cd6898afff4c31a0da06905
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A TSPO TAMALIN RGS12

2.67e-04180774499d5fe71e0dc20cffdf85e3b3f14eb4e83e3a3d
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

CCM2L ARMCX4 RGS12 RYR2

2.78e-041827747af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCellE18.5-samps-Endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

CCM2L ARMCX4 RGS12 RYR2

2.78e-04182774e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PHOX2A ASPHD1 ALK RYR2

2.84e-041837747e2bac8b005155888ff4b41ef2e1d975dc17abc7
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GLRX5 KIF26A SMOX SHISA7

2.84e-04183774b52d7683dc6652766e814ebe935c264ecd610c4b
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GLRX5 KIF26A SMOX SHISA7

2.84e-041837741db466cf757813322db1cdcc0bf1d91c062fd9de
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-erythrocytic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GLRX5 KIF26A SMOX SHISA7

2.84e-041837741d77d8d8c8f78f43dd8864e76f294ee66d4942c2
ToppCellPosterior_cortex-Neuronal-Excitatory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KCNC4 HAPLN4 LTK RYR2

2.90e-0418477425ccf08a8a26d7e7827b6357f33a53aaf423577d
ToppCellCV-Moderate-4|CV / Virus stimulation, Condition and Cluster

NR2F6 GLRX5 ASPHD1 SMOX

2.90e-0418477490f5b447064743246b09a6c47bf561efafa15e1f
ToppCellwk_08-11-Epithelial-PNS-PCP4+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PHOX2A RELL2 POU3F2 ALK

2.90e-04184774eac2a9089913f33a961ba11519b53645790f2056
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INSC KANK4 POU3F1 POU3F2

2.90e-04184774da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 KCNC3 RELL2 EPHA8

2.90e-041847747d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCellwk_20-22-Epithelial-PNS-intermediate_Schwann|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NR2F6 TPCN2 KANK4 POU3F1

2.90e-041847744e3ba64692868563a579902aa9c6f88cab5bce26
ToppCelldroplet-Marrow-nan-18m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLRX5 FAM117A SMOX PRNP

2.96e-04185774a45756f91b62cf0fac3582786e5868deb8fd8435
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCM2L ALPK3 TAMALIN SPRED3

2.96e-04185774fa94c4a1660967f211ba095606cd0aa37d38e17a
ToppCell343B-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PRR12 NR2F6 TAMALIN PDCD4

2.96e-041857741b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RFLNB C11orf96 KANK4 KCTD17

2.96e-04185774512a195ebbae445afe3722a3943020080daf2f3c
ToppCell343B-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PRR12 NR2F6 TAMALIN PDCD4

2.96e-0418577402cbf492bc40abebaa93a3a208888afae72fbe06
ToppCellCV-Moderate-4|Moderate / Virus stimulation, Condition and Cluster

NR2F6 GLRX5 ASPHD1 SMOX

2.96e-041857744a3ce0c603c2ffe11f0f00775b6af4f6d9a6070a
ToppCelldroplet-Heart-nan-18m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INSC KANK4 POU3F1 POU3F2

2.96e-04185774c61267cfadea018794f7964904445787629a40d1
ToppCelldroplet-Heart-nan-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INSC KANK4 POU3F1 POU3F2

2.96e-041857743a592719d5643011954f89d5bb61a5e94682b68e
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PHOX2A ASPHD1 KCNC3 LTK

3.02e-0418677418fd311252299d6d30ddb32002ed069056108206
ToppCellSubstantia_nigra-Neuronal-Inhibitory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ASPHD1 RELL2 GLG1 SPRED3

3.02e-041867749d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCellAdult-Endothelial-endothelial_cell_of_artery|Adult / Lineage, Cell type, age group and donor

CCM2L KIF26A TAMALIN RYR3

3.02e-041867742d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PHOX2A ASPHD1 ALK RYR2

3.02e-0418677415f2e5905486e33f6f7b3b3e9758a0559e8c61ee
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

INSC POU3F1 POU3F2 PRNP

3.09e-041877746f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCell(0)_Myeloid-(01)_Dendritic_cell-(011)_pDC|(01)_Dendritic_cell / immune cells in Peripheral Blood (logTPM normalization)

RFLNB OPN3 MARCHF9 LTK

3.09e-04187774068502efa3f0ac4cea2fa4a18d1c2f686a4fba54
ToppCellCerebellum-Neuronal|Cerebellum / BrainAtlas - Mouse McCarroll V32

SHANK1 ASPHD1 RELL2 HAPLN4

3.09e-0418777461b9d6eb131a674598aa8409d7fa909c8765442d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNC3 KCNC4 HAPLN4 EPHA8

3.15e-041887741efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OPN3 TAMALIN RYR1 ZNF503

3.21e-04189774c81b38cda4525254fe4fa137a4c9bc9abe0363bb
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNC3 KCNC4 HAPLN4 EPHA8

3.21e-04189774f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

OPN3 TAMALIN RYR1 ZNF503

3.21e-04189774807922b5ea0faddd3abfa9ec1b53f3f2b00e61bf
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RFLNB CCM2L KIF26A ARMCX4

3.28e-04190774eae5bcdb8a35f3fba4d25854c1a43f83f80832a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 HOXD11 ATRNL1 KANK4

3.28e-0419077470c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RFLNB CCM2L KIF26A ARMCX4

3.28e-041907743346bfd0474828b3729cffa9f4cc57b04dd30443
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 CCM2L TAMALIN RYR3

3.34e-04191774b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAPN12 INSC DENND11 PDCD4

3.34e-04191774f1935e8f8467a2bc30588b7f2cc3b94e9c83b268
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SMOX TAMALIN RYR1 ZNF503

3.34e-041917742699e9bb872f2b561bb976dfdc2746e359bc9daf
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAPN12 INSC DENND11 PDCD4

3.34e-041917741161e465c50c2071764279e01cf08b1048cce0e3
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SMOX TAMALIN RYR1 ZNF503

3.34e-041917744b94c8b0183ae07d173646b7e7e1d9db04ec9637
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

OPN3 SMOX TAMALIN RYR1

3.34e-041917745c0c44612b4cdbf89c0f1f219416374a7541f610
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CAPN12 INSC DENND11 PDCD4

3.34e-041917747a4fe96989f72159385270c712342ba3e1ca6fc3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 HOXD11 ATRNL1 KANK4

3.34e-04191774107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RFLNB CCM2L KIF26A ARMCX4

3.34e-04191774b270c3dd5952f56b9bdceabe13e298fe6757563b
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RFLNB CCM2L KIF26A ARMCX4

3.34e-0419177427f23c2254b610abac1a88d0fecff305addde9da
ToppCellControl-Lymphoid_T/NK-NK_CD56bright|Control / Disease group, lineage and cell class

CAPN12 INSC DENND11 PDCD4

3.34e-04191774e842f29bc03ed6734b2a7b975e7830a498f2743c
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CAPN12 INSC DENND11 PDCD4

3.34e-04191774c023ca893ceae19b54967096f6e2588dc39fa268
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 HOXD11 ATRNL1 KANK4

3.34e-04191774bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RFLNB KIF26A C11orf96 KANK4

3.41e-04192774f4cd65e6c5b17bcabf45fe5b687246c72e7975f7
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RFLNB KIF26A C11orf96 KANK4

3.41e-04192774bcd8876235be503186f119653b39476488c0fa15
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LONRF1 ATRNL1 C11orf96

3.48e-04193774c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCellwk_15-18-Epithelial-PNS|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PHOX2A ASPHD1 INSC ALK

3.48e-04193774ca65f8f93058ad50d89e69e06c10deeb46dbfc87
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LONRF1 ATRNL1 C11orf96

3.48e-041937745b602b1702283184bd3943c2a6f2290b7c37e407
Drug2-hydroxycarbazole

RYR1 RYR2 RYR3

3.72e-083773CID000093551
Drugcis-diammineplatinum(II

RYR1 RYR2 RYR3

3.72e-083773CID000159790
Drug2-hydroxyheptanoic acid

RYR1 RYR2 RYR3

3.72e-083773CID002750949
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR1 RYR2 RYR3

3.72e-083773CID005748312
Drug8N3-cADPR

RYR1 RYR2 RYR3

3.72e-083773CID000127713
Drugaminodantrolene

RYR1 RYR2 RYR3

3.72e-083773CID009570289
DrugPCB74

RYR1 RYR2 RYR3

1.48e-074773CID000036218
Drug148504-47-6

RYR1 RYR2 RYR3

1.48e-074773CID006444275
DrugSC 38249

RYR1 RYR2 RYR3

1.48e-074773CID000134834
DrugAC1L1U7A

RYR1 RYR2 RYR3

1.48e-074773CID000035682
DrugMBED

RYR1 RYR2 RYR3

7.38e-076773CID000129958
Drugchloro-m-cresol

RYR1 RYR2 RYR3

7.38e-076773CID000012008
DrugAC1O528X

RYR1 RYR2 RYR3

7.38e-076773CID006475857
DrugNSC114784

RYR1 RYR2 RYR3

7.38e-076773CID000419425
Drugnitrendipine

TPCN2 TSPO ORAI3 RYR1 RYR2 RYR3

1.01e-0698776CID000004507
DrugAzumoleno

RYR1 RYR2 RYR3

1.29e-067773CID000056259
DrugBr2BAPTA

RYR1 RYR2 RYR3

1.29e-067773CID003081001
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

RYR1 RYR2 RYR3

1.29e-067773CID009547999
DrugCinildipine

TPCN2 ORAI3 RYR1 RYR2 RYR3

1.29e-0656775CID000002752
Drugnilvadipine

TPCN2 ORAI3 RYR1 RYR2 RYR3

1.83e-0660775CID000004494
Druglercanidipine

TPCN2 ORAI3 RYR1 RYR2 RYR3

2.34e-0663775CID000065866
Druggallopamil

TPCN2 ORAI3 RYR1 RYR2 RYR3

3.18e-0667775CID000001234
DrugAC1L2AC7

TPCN2 ORAI3 RYR1 RYR2 RYR3

3.68e-0669775CID000068733
DrugPCB 95

RYR1 RYR2 RYR3

4.39e-0610773CID000038012
DrugAntimycin A [1397-94-0]; Up 200; 7.2uM; PC3; HT_HG-U133A

THSD4 ASPHD1 ALK PDCD4 RYR1 KCTD17 ZNF646

4.86e-061987775053_UP
DrugCAS 298-57-7

TPCN2 ORAI3 RYR1 RYR2 RYR3

4.87e-0673775CID000002761
Drugethosuximide

TPCN2 ORAI3 RYR1 RYR2 RYR3

5.21e-0674775CID000003291
DrugPCB 66

RYR1 RYR2 RYR3

6.02e-0611773CID000036185
DrugR 478

RYR1 RYR2 RYR3

6.02e-0611773CID000084223
Drug8-amino-cADPR

RYR1 RYR2 RYR3

6.02e-0611773CID003081323
Drugnisoldipine

TPCN2 ORAI3 RYR1 RYR2 RYR3

6.75e-0678775CID000004499
DrugN-cyclopentyl-N-cyclobutylformamide

KCNC3 COIL RYR1 RYR2 RYR3

7.19e-0679775CID005287890
DrugRyanodine

RYR1 RYR2 RYR3

8.00e-0612773ctd:D012433
DrugNAADP

COIL RYR1 RYR2 RYR3

9.09e-0639774CID000123952
Drug5'-adenylyl (beta,gamma-methylene)diphosphonate

RYR1 RYR3

1.13e-052772ctd:C005147
DrugFPL 64176

RYR1 RYR2 RYR3

1.64e-0515773CID000003423
DrugGvapspat amide

RYR1 RYR2 RYR3

1.64e-0515773CID000125015
Drugmanidipine

TPCN2 ORAI3 RYR1 RYR2 RYR3

1.77e-0595775CID000004008
Drugisradipine

TPCN2 ORAI3 RYR1 RYR2 RYR3

2.27e-05100775CID000003784
Drugkazinol B

RYR1 RYR2 RYR3

2.44e-0517773CID000480869
Drugloperamide

TPCN2 ORAI3 RYR1 RYR2 RYR3

2.88e-05105775CID000003954
Drugmethylcoumarin

RYR1 RYR2 RYR3

2.93e-0518773CID000007092
Drug1,1'-diheptyl-4,4'-bipyridinium

RYR1 RYR3

3.38e-053772CID000080262
Drugflubendiamide

RYR1 RYR3

3.38e-053772CID011193251
DrugAC1L380G

RYR1 RYR2 RYR3

3.47e-0519773CID000084698
DrugAC1MW7VF

RYR1 RYR2 RYR3

3.47e-0519773CID000414699
Druglamotrigine

TPCN2 ORAI3 RYR1 RYR2 RYR3

4.64e-05116775CID000003878
Drugindo-1/AM

RYR1 RYR2 RYR3

4.73e-0521773CID000123918
Drugmibefradil

TPCN2 ORAI3 RYR1 RYR3

6.59e-0564774CID000060662
DrugA-30

RYR1 RYR3

6.74e-054772CID003028528
DrugBastadin 10

RYR1 RYR3

6.74e-054772CID009589366
Drugbepridil

TPCN2 ORAI3 RYR1 RYR2 RYR3

6.89e-05126775CID000002351
Drugpimozide

TPCN2 ORAI3 RYR1 RYR2 RYR3

7.15e-05127775CID000016362
DrugT0702

RYR1 RYR2 RYR3

8.11e-0525773CID000005908
Druglanthanum

TPCN2 ORAI3 RYR1 RYR2 RYR3

9.88e-05136775CID000023926
DrugA 68930

RYR1 RYR2

1.12e-045772ctd:C065380
DrugDantrolene-13C3

TPCN2 ORAI3 RYR1 RYR2 RYR3

1.34e-04145775CID000002951
Drugnimodipine

TPCN2 ORAI3 RYR1 RYR2 RYR3

1.34e-04145775CID000004497
Drugnicardipine

TPCN2 ORAI3 RYR1 RYR2 RYR3

1.34e-04145775CID000004473
Drug2,4-xylidinothiazoline

RYR1 RYR2 RYR3

1.41e-0430773CID000099296
DrugLOPAC

RYR1 RYR2 RYR3

1.41e-0430773CID000062696
DrugM-HN

RYR1 RYR2 RYR3

1.56e-0431773CID000015450
DrugBay K 8644

TPCN2 ORAI3 RYR1 RYR2 RYR3

1.57e-04150775CID000002303
DrugMW 1

TRIOBP POU3F1 RYR1 RYR2 RYR3

1.62e-04151775CID000073965
DrugNSC692750

RYR1 RYR3

1.68e-046772CID000078910
Drugprocaine

TPCN2 ORAI3 RYR1 RYR2 RYR3

1.72e-04153775CID000004914
DrugM3/M4

RYR1 RYR2 RYR3

1.72e-0432773CID000486507
DrugcADPR

COIL RYR1 RYR2 RYR3

1.73e-0482774CID000123847
DrugCNS 1145

RYR1 RYR2 RYR3

1.89e-0433773CID000190902
DrugIHC-64

RYR1 RYR2 RYR3

1.89e-0433773CID000162753
Drugmag-indo-1

RYR1 RYR3

2.34e-047772CID000131881
DrugCHEBI:564108

RYR1 RYR3

2.34e-047772CID006400637
Drug1,2-dichlorohexafluorocyclobutane

RYR1 RYR2 RYR3

2.66e-0437773CID000009643
Drugmag-fura-2

RYR1 RYR2 RYR3

2.66e-0437773CID000123839
Drug4-chloro-m-cresol

RYR1 RYR2 RYR3

2.66e-0437773CID000001732
DrugAC1NUZ8M

TPCN2 ORAI3 RYR1 RYR3

2.70e-0492774CID000073211
Druggabapentin

TPCN2 ORAI3 RYR1 RYR2 RYR3

2.73e-04169775CID000003446
Drugfelodipine

TPCN2 ORAI3 RYR1 RYR2 RYR3

2.73e-04169775CID000003333
DrugAC1L98DX

RYR1 RYR2 RYR3

2.88e-0438773CID000439957
Drugepps

KCNC3 KCNC4 RYR3

3.36e-0440773CID000085255
Drugdipyrone

RYR1 RYR2 RYR3

3.36e-0440773CID000003110
Drugborate

ORAI3 RYR1 RYR2 RYR3

3.43e-0498774CID000007628
DrugDantrolene

RYR1 RYR2 RYR3

3.61e-0441773ctd:D003620
Druglactosyl lysosphingolipid

RYR1 RYR3

4.00e-049772CID006439268
DrugFLA 365

RYR1 RYR3

4.00e-049772CID000072776
Drugescina

RYR1 RYR2 RYR3

4.46e-0444773CID006433489
Drug4,4'-dithiodipyridine

RYR1 RYR2 RYR3

4.76e-0445773CID000075846
DrugNSC759576

TPCN2 ORAI3 RYR1 RYR2 RYR3

4.78e-04191775CID000003075
DrugAC1N38XE

RYR1 RYR3

4.99e-0410772CID004060965
Drugdihydropyridine

TPCN2 ORAI3 RYR1 RYR2 RYR3

5.01e-04193775CID000104822
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR2 RYR3

1.22e-083693DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR2 RYR3

1.22e-083693DOID:8545 (implicated_via_orthology)
Diseaseleukemia inhibitory factor measurement

SARM1 SMOX

3.22e-054692EFO_0801764
Diseasesyntaxin-1a measurement

SARM1 RGS12

5.36e-055692EFO_0020759
Diseaseneuroblastoma (implicated_via_orthology)

LTK ALK

5.36e-055692DOID:769 (implicated_via_orthology)
Diseasetuberculosis

GLRX5 KCNC4 KIF26A TUSC1 RGS12

1.54e-04216695MONDO_0018076
Diseaseprostate carcinoma, type 2 diabetes mellitus

TPCN2 GDF7 POU5F1B

3.62e-0459693EFO_0001663, MONDO_0005148
DiseaseMalignant neoplasm of breast

ADAMTS19 NR2F6 HOXD11 HAPLN4 MPLKIP SMOX ALK PDCD4 ZNF646

8.65e-041074699C0006142
Diseasepulmonary hypertension (biomarker_via_orthology)

RYR1 RYR2 RYR3

8.84e-0480693DOID:6432 (biomarker_via_orthology)
Diseaseamino acid measurement

ADAMTS19 GLRX5 POU3F2 TUSC1 ALK RYR2 RYR3

1.03e-03678697EFO_0005134

Protein segments in the cluster

PeptideGeneStartEntry
MAGAAAGGRGGGAWG

FAM117A

1

Q9C073
GGAWGPGRGGAGGLR

FAM117A

11

Q9C073
RGWGAGGRSGAGGDG

ALPK3

211

Q96L96
GWGGGAAEARAGGGG

CCM2L

206

Q9NUG4
SWERRHGGGGGGGGA

CCM2L

246

Q9NUG4
GGGGAGKPGGSWERR

CCM2L

256

Q9NUG4
IGGGFWPGAGDQTGG

ARMCX4

1581

Q5H9R4
GGWGGPGGDTNGVDK

NR2F6

6

P10588
AGGSGGSADPGWVRG

ADAMTS19

51

Q8TE59
GSADPGWVRGVGGGG

ADAMTS19

56

Q8TE59
GGRGLWTVGGGGSPT

KIRREL3-AS3

36

Q8N7Y1
ACGGGGAHGPGWQAA

ORAI3

231

Q9BRQ5
GGGGDGPWGAEPGWV

POU5F1B

16

Q06416
APGEGDGGGGGFGSW

CCDC43

11

Q96MW1
PGGGGWGSGSSFRGT

MPLKIP

16

Q8TAP9
WGSGSSFRGTPGGGG

MPLKIP

21

Q8TAP9
PGTGARGGGRRGWGG

MED14OS

51

P0DP75
PQGRGRFWEVGGGSG

LONRF1

21

Q17RB8
GTGGELGGQGNWGPE

ASPHD1

41

Q5U4P2
EGVPGSRRWAGGGGG

LTK

196

P29376
SRRWAGGGGGGGGAT

LTK

201

P29376
GRGGAAGGGGGWTSR

LTK

266

P29376
TLGWAAAGGFGGGGG

LTK

306

P29376
GGAGGKGVWGTPGQV

PDCD4

116

Q53EL6
GPWGSGVGGGGTVRL

NEMP1

16

O14524
GWRRSGSNGGGQAPG

COIL

366

P38432
TGGGGGGDWAGGPHL

POU3F1

76

Q03052
AGPEQGHSAGGGGWC

KIF26A

56

Q9ULI4
GGGGGGAPGALWTEA

TAMALIN

341

Q7Z6J2
APPAGAGGRAAGGWG

KCTD17

16

Q8N5Z5
RGGRGGGCGWAPFAG

MARCHF9

31

Q86YJ5
GYWDGGGAAGAEGPA

OPN3

11

Q9H1Y3
GPPARRGGAGAGGGW

GLG1

96

Q92896
EGPWGGWGAAGARGP

CAPN12

401

Q6ZSI9
GRGAGGGGLWGPGVR

GLRX5

16

Q86SX6
GGGLWGPGVRAAGSG

GLRX5

21

Q86SX6
GCGVGGQPLGGRGQW

LINC01599

241

Q8WXQ3
QPQAGGWGRGGGGGA

DENND11

26

A4D1U4
GWGRGGGGGARPAAE

DENND11

31

A4D1U4
GSGGGGGLTVGDWLD

EPHA8

926

P29322
AKWPYRGGGGGGSAG

HOXD11

71

P31277
APGVWRARPAGGGGG

ATRNL1

16

Q5VV63
RARPAGGGGGGASSW

ATRNL1

21

Q5VV63
QKRQEGGGGRGGWGG

FAM98B

326

Q52LJ0
GEGPEGAGAGLGSWG

FIZ1

171

Q96SL8
GNGEAASEGPGGWGL

INSC

6

Q1MX18
GPQGGTRGAGGFLWG

KANK4

511

Q5T7N3
WAGGGGWAGGARDPA

HAPLN4

381

Q86UW8
GSRGSGWSGPFGHQG

DDX53

26

Q86TM3
SPEHNGRGGGGGAWE

DDHD1

11

Q8NEL9
GRGGGGGAWELGSDA

DDHD1

16

Q8NEL9
GAGEGWGGNGVGDDL

RYR1

696

P21817
YPGGGEEWGGNGVGD

RYR2

706

Q92736
SPLGSWNGSGSGGGG

MAP3K11

11

Q16584
DQGKAGGGSPGWGCA

PANK1

36

Q8TE04
AARYGEAGEGPGWGG

VARS1

21

P26640
RSWGSGGGQDPGGGQ

RELL2

191

Q8NC24
SPSHWGLAAGGGGGE

RFLNB

36

Q8N5W9
AGGAGAGPSWHGRSG

OPLAH

1121

O14841
GFGWPGGGGSAAEER

GDF7

251

Q7Z4P5
QAGWLEGGRTGGAGG

SHISA7

161

A6NL88
LSGHGGGWGPSSLGG

PRR12

541

Q9ULL5
GGWGPSSLGGGGEAS

PRR12

546

Q9ULL5
WSGGSGAGRGGRGGW

NFATC2IP

11

Q8NCF5
WITALSHGGGGGGGG

POU3F2

61

P20265
EGGLGPGGWWGCGEP

TRIOBP

1451

Q9H2D6
AAGGALPWARGGSGG

SHANK1

1886

Q9Y566
LPWARGGSGGGGDSH

SHANK1

1891

Q9Y566
VHEWAGGGGGGGGAT

ALK

811

Q9UM73
PSGAGWRGAGGAGEG

C11orf96

161

Q7Z7L8
HGGAGGPGLSASEGW

ZNF513

496

Q8N8E2
SGSGVRWISGGGGGA

USP51

11

Q70EK9
GPGGSAWDGVGGRGA

RGS12

451

O14924
GGGTGPWWAAGGRGP

SARM1

36

Q6SZW1
APYPGGGEGWGGNGV

RYR3

691

Q15413
RDDSSGGWLPVGGGG

SPRED3

11

Q2MJR0
PLAGAGGLGWGGRGY

SPRED3

206

Q2MJR0
LWAGVAGGGGGGPGA

PHOX2A

231

O14813
NGLGLGGSPAGQWGG

TSPO

11

B1AH88
GEGGQGGEEPRGGRW

SMOX

291

Q9NWM0
SWGAGKAGGWPVGGG

ZNF646

1456

O15015
HGGGWGQPHGGGWGQ

PRNP

61

P04156
PHGGGWGQPHGGGWG

PRNP

76

P04156
WGQPHGGGWGQGGGT

PRNP

81

P04156
GVAPAGGSGGLWSGA

nan

136

Q8N1X5
GGGGGGGADPAWTSA

ZNF503

21

Q96F45
DDGGGGAPGVWGAWG

THSD4

46

Q6ZMP0
PGAGDPGAGGCGRRW

TIGD5

256

Q53EQ6
RGGGGGGGGWRAAQD

TRA2B

241

P62995
LLGGARGGGGDWPAG

TPCN2

11

Q8NHX9
PGPAGGGGGGSRWAE

TRIR

16

Q9BQ61
PSGGGGGVGWRGRAD

TUSC1

41

Q2TAM9
TGWEGGWRGGQGGAC

nan

106

Q6ZPA2
GPPGGAGGAGGTWWR

KCNC3

256

Q14003
AGHGAGSGGCRGWQP

KCNC4

196

Q03721
SGAEGDGGWRPGGPG

JMJD8

21

Q96S16