Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-7 ERVK-10 ERVK-8 ERVK-11

7.78e-07111424GO:0004523
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-7 ERVK-10 ERVK-8 ERVK-11

2.32e-06141424GO:0003964
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-7 ERVK-10 DROSHA ERVK-8 ERVK-11

6.15e-06371425GO:0016891
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25

6.15e-06371425GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25

7.04e-06381425GO:0070001
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.34e-05211424GO:0035613
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-7 ERVK-10 DROSHA ERVK-8 ERVK-11

1.84e-05461425GO:0016893
GeneOntologyMolecularFunction1-phosphatidylinositol-3-kinase activity

PIK3C2B PIK3C3 PIK3CD

5.57e-05111423GO:0016303
GeneOntologyMolecularFunctionstretch-activated, monoatomic cation-selective, calcium channel activity

NALF1 NALF2

1.50e-0431422GO:0015275
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.50e-04381424GO:0034061
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-7 ERVK-10 DROSHA ERVK-8 ERVK-11

2.50e-04791425GO:0004521
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK1 DOCK3 ARHGEF28 ABR DOCK11 ANKRD27 EIF2B3 VAV2

2.52e-042311428GO:0005085
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

SLK SAMD8 AK9 ERVK-7 ERVK-10 BLK CCNE1 AATK PIK3C2B PIK3C3 PIK3CD ERVK-8 PRKAG1 KDR MAP3K15 PPIP5K2 ERVK-11

3.68e-0493814217GO:0016772
GeneOntologyMolecularFunctionendonuclease activity

ERVK-7 ERVK-10 DROSHA ERVK-8 LAS1L ERVK-11

4.29e-041361426GO:0004519
GeneOntologyMolecularFunctionphosphatidylinositol kinase activity

PIK3C2B PIK3C3 PIK3CD

8.12e-04261423GO:0052742
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

RARS1 ETF1 ERVK-7 ERVK-10 DROSHA ERVK-8 DDX60L TRMT5 ERVK-11 DDX24

8.14e-0441714210GO:0140098
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK1 DOCK3 ARHGEF28 ABR DOCK11 ARHGAP10 SRGAP2 ANKRD27 SRGAP1 EIF2B3 VAV2

1.02e-0350714211GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK1 DOCK3 ARHGEF28 ABR DOCK11 ARHGAP10 SRGAP2 ANKRD27 SRGAP1 EIF2B3 VAV2

1.02e-0350714211GO:0030695
GeneOntologyMolecularFunction1-phosphatidylinositol-4-phosphate 3-kinase activity

PIK3C2B PIK3CD

1.03e-0371422GO:0035005
GeneOntologyMolecularFunctionmechanosensitive monoatomic cation channel activity

NALF1 NALF2

1.03e-0371422GO:0140135
GeneOntologyMolecularFunctionsmall GTPase binding

DOCK1 DOCK3 DOCK11 SRGAP2 ANKRD27 RASSF1 SRGAP1 WDR44

2.13e-033211428GO:0031267
GeneOntologyBiologicalProcessDNA integration

KRBA2 ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.77e-08131425GO:0015074
DomainsrGAP2

SRGAP2 SRGAP2C SRGAP2B

3.78e-0731363IPR030252
DomainFCH

SRGAP2 SRGAP2C SRGAP1 SRGAP2B

1.78e-05221364PF00611
DomainFCH

SRGAP2 SRGAP2C SRGAP1 SRGAP2B

1.78e-05221364SM00055
DomainPI3K_C2

PIK3C2B PIK3C3 PIK3CD

2.06e-0581363SM00142
DomainPI3K_C2_dom

PIK3C2B PIK3C3 PIK3CD

2.06e-0581363IPR002420
DomainPI3K_C2

PIK3C2B PIK3C3 PIK3CD

2.06e-0581363PF00792
DomainPI3K_C2

PIK3C2B PIK3C3 PIK3CD

2.06e-0581363PS51547
DomainFCH_dom

SRGAP2 SRGAP2C SRGAP1 SRGAP2B

2.14e-05231364IPR001060
DomainF_BAR

SRGAP2 SRGAP2C SRGAP1 SRGAP2B

3.02e-05251364IPR031160
DomainF_BAR

SRGAP2 SRGAP2C SRGAP1 SRGAP2B

3.02e-05251364PS51741
DomainPI3Ka

PIK3C2B PIK3C3 PIK3CD

3.07e-0591363PF00613
DomainPI3Ka

PIK3C2B PIK3C3 PIK3CD

3.07e-0591363SM00145
Domain-

PIK3C2B PIK3C3 PIK3CD

3.07e-05913631.25.40.70
DomainPI_Kinase

PIK3C2B PIK3C3 PIK3CD

4.37e-05101363IPR015433
DomainPInositide-3_kin_accessory_dom

PIK3C2B PIK3C3 PIK3CD

4.37e-05101363IPR001263
DomainPIK_HELICAL

PIK3C2B PIK3C3 PIK3CD

4.37e-05101363PS51545
DomainFAM155

NALF1 NALF2

5.26e-0521362IPR029604
DomainDHR-1_domain

DOCK1 DOCK3 DOCK11

5.97e-05111363IPR027007
DomainDHR_2

DOCK1 DOCK3 DOCK11

5.97e-05111363PS51651
DomainDHR_1

DOCK1 DOCK3 DOCK11

5.97e-05111363PS51650
DomainDHR-2

DOCK1 DOCK3 DOCK11

5.97e-05111363PF06920
DomainDOCK

DOCK1 DOCK3 DOCK11

5.97e-05111363IPR026791
DomainDOCK_C

DOCK1 DOCK3 DOCK11

5.97e-05111363IPR010703
DomainDOCK-C2

DOCK1 DOCK3 DOCK11

5.97e-05111363PF14429
DomainDHR-2

DOCK1 DOCK3 DOCK11

5.97e-05111363IPR027357
DomainVps26-related

VPS26B VPS26A

1.57e-0431362IPR028934
DomainVps26

VPS26B VPS26A

1.57e-0431362PF03643
DomainPI3/4_kinase_CS

PIK3C2B PIK3C3 PIK3CD

1.61e-04151363IPR018936
DomainSH3

DOCK1 DOCK3 ARHGAP10 SRGAP2 NEB BLK SRGAP1 VAV2

1.86e-042161368SM00326
DomainSH3

DOCK1 DOCK3 ARHGAP10 SRGAP2 NEB BLK SRGAP1 VAV2

1.86e-042161368PS50002
Domain-

PIK3C2B PIK3C3 PIK3CD

1.97e-041613631.10.1070.11
DomainPI3Kc

PIK3C2B PIK3C3 PIK3CD

1.97e-04161363SM00146
DomainSH3_1

DOCK1 ARHGAP10 SRGAP2 NEB BLK SRGAP1 VAV2

2.00e-041641367PF00018
DomainSH3_domain

DOCK1 DOCK3 ARHGAP10 SRGAP2 NEB BLK SRGAP1 VAV2

2.11e-042201368IPR001452
DomainPI3_PI4_kinase

PIK3C2B PIK3C3 PIK3CD

2.84e-04181363PF00454
DomainPI3_4_KINASE_1

PIK3C2B PIK3C3 PIK3CD

2.84e-04181363PS00915
DomainPI3_4_KINASE_2

PIK3C2B PIK3C3 PIK3CD

2.84e-04181363PS00916
DomainPI3/4_kinase_cat_dom

PIK3C2B PIK3C3 PIK3CD

2.84e-04181363IPR000403
DomainPI3_4_KINASE_3

PIK3C2B PIK3C3 PIK3CD

2.84e-04181363PS50290
DomainPBC

PBX1 PBX2

3.13e-0441362PF03792
DomainPBX

PBX1 PBX2

3.13e-0441362IPR005542
DomainDOCK_N

DOCK1 DOCK3

5.19e-0451362PF16172
DomainDOCK_N

DOCK1 DOCK3

5.19e-0451362IPR032376
DomainNACHT

NLRP12 NLRP14 NOD1

6.01e-04231363PS50837
DomainNACHT_NTPase

NLRP12 NLRP14 NOD1

6.01e-04231363IPR007111
Domain-

ABR PIK3C2B PIK3C3 PIK3CD UNC13C FER1L5

7.55e-0414813662.60.40.150
DomainAcid_Pase_AS

ACP3 PPIP5K2

7.75e-0461362IPR033379
DomainC1_1

ARHGEF28 RASSF1 UNC13C VAV2

7.88e-04571364PF00130
DomainTPR-contain_dom

TTC21A PTPN23 AIP TRANK1 CDC16 TTC12

8.10e-041501366IPR013026
DomainARM-type_fold

DOCK1 DOCK3 DOCK11 INTS1 USP9Y PIK3C2B PIK3C3 PIK3CD TTC12

8.55e-043391369IPR016024
DomainPI3K_Ras-bd_dom

PIK3C2B PIK3CD

1.08e-0371362IPR000341
DomainHIS_ACID_PHOSPHAT_2

ACP3 PPIP5K2

1.08e-0371362PS00778
DomainPI3K_rbd

PIK3C2B PIK3CD

1.08e-0371362SM00144
DomainPI3K_rbd

PIK3C2B PIK3CD

1.08e-0371362PF00794
DomainHIS_ACID_PHOSPHAT_1

ACP3 PPIP5K2

1.08e-0371362PS00616
DomainPI3K_RBD

PIK3C2B PIK3CD

1.08e-0371362PS51546
DomainRhoGAP

ABR ARHGAP10 SRGAP2 SRGAP1

1.08e-03621364SM00324
DomainRhoGAP

ABR ARHGAP10 SRGAP2 SRGAP1

1.15e-03631364PF00620
DomainRhoGAP_dom

ABR ARHGAP10 SRGAP2 SRGAP1

1.22e-03641364IPR000198
DomainZF_DAG_PE_1

ARHGEF28 RASSF1 UNC13C VAV2

1.22e-03641364PS00479
DomainZF_DAG_PE_2

ARHGEF28 RASSF1 UNC13C VAV2

1.22e-03641364PS50081
DomainRHOGAP

ABR ARHGAP10 SRGAP2 SRGAP1

1.22e-03641364PS50238
Domain-

ABR ARHGAP10 SRGAP2 SRGAP1

1.22e-036413641.10.555.10
DomainC2_dom

ABR PIK3C2B PIK3C3 PIK3CD UNC13C FER1L5

1.28e-031641366IPR000008
DomainC1

ARHGEF28 RASSF1 UNC13C VAV2

1.29e-03651364SM00109
DomainTPR_REGION

TTC21A PTPN23 AIP TRANK1 CDC16 TTC12

1.33e-031651366PS50293
DomainTPR

TTC21A PTPN23 AIP TRANK1 CDC16 TTC12

1.33e-031651366PS50005
DomainPE/DAG-bd

ARHGEF28 RASSF1 UNC13C VAV2

1.37e-03661364IPR002219
DomainHis_Pase_clade-2

ACP3 PPIP5K2

1.43e-0381362IPR000560
DomainHis_Phos_2

ACP3 PPIP5K2

1.43e-0381362PF00328
DomainNPY_rcpt

PROKR1 QRFPR

1.83e-0391362IPR000611
DomainTPR_repeat

TTC21A AIP TRANK1 CDC16 TTC12

2.90e-031331365IPR019734
DomainC2

ABR PIK3C2B PIK3C3 UNC13C FER1L5

3.30e-031371365SM00239
DomainRho_GTPase_activation_prot

ABR ARHGAP10 SRGAP2 SRGAP1

3.91e-03881364IPR008936
Domain-

KIFBP TTC21A AIP TRANK1 CDC16 TTC12

4.11e-0320713661.25.40.10
DomainA/G_cyclase_CS

ADCY2 GUCY1A1

6.66e-03171362IPR018297
DomainCyclin_C-dom

CCNJL CCNE1

6.66e-03171362IPR004367
DomainCyclin_C

CCNJL CCNE1

6.66e-03171362PF02984
DomainCyclin_C

CCNJL CCNE1

6.66e-03171362SM01332
DomainTPR-like_helical_dom

KIFBP TTC21A AIP TRANK1 CDC16 TTC12

7.24e-032331366IPR011990
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

DOCK1 DOCK3 SLK ARHGEF28 ABR DOCK11 ARHGAP10 SRGAP2 MFN1 CCNE1 NDC80 WDR11 PIK3C3 SRGAP1 CENPI KIF5B VAV2

1.68e-0572010317M41838
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

DOCK1 SLK ARHGEF28 ABR DOCK11 ARHGAP10 SRGAP2 MFN1 CCNE1 NDC80 WDR11 PIK3C3 SRGAP1 CENPI KIF5B VAV2

1.81e-0564910316MM15690
PathwayREACTOME_RAC1_GTPASE_CYCLE

DOCK1 DOCK3 ABR DOCK11 ARHGAP10 SRGAP2 SRGAP1 VAV2

5.98e-051841038M41809
PathwayREACTOME_CDC42_GTPASE_CYCLE

ABR DOCK11 ARHGAP10 SRGAP2 SRGAP1 VAV2

6.36e-05941036MM15598
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK1 ABR MAOA ARHGAP10 TTC21A ACP3 TMEM212 ATP9B SRGAP2 CPT1A ZNF462 EFNA1 POGLUT1 WDR11 GUCY1A1 PIK3C3 SUPT6H TTC12 PRKAG1 CCAR1 PBX1 PBX2 VAV2 FRMD3 RAVER1

2.41e-0914891442528611215
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

UBR1 RARS1 VPS33A AIP CPT1A PIK3C3 SUPT6H CDC16 PRKAG1 CCAR1

2.16e-082121441033853758
Pubmed

Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation.

SRGAP2 SRGAP2C SRGAP2B

6.95e-083144322559944
Pubmed

Human immunodeficiency virus type 1 tat-mediated cytotoxicity of human brain microvascular endothelial cells.

PIK3C2B PIK3C3 PIK3CD KDR

1.36e-0712144414602571
Pubmed

Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication.

SRGAP2 SRGAP2C SRGAP2B

2.77e-074144322559943
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

UBR1 SLK ARHGEF28 PARG ANKRD27 WDR11 DROSHA SHCBP1 ASB3 CCAR1 CRYBG3 PPIP5K2 EDEM1 RAVER1

5.85e-076501441438777146
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-10 ERVK-18 ERVK-25 ERVK-11

8.24e-0718144418664271
Pubmed

HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells.

PIK3C2B PIK3C3 PIK3CD KDR

1.95e-0622144411994280
Pubmed

Network organization of the human autophagy system.

DOCK1 VPS33A CPT1A WDR11 PIK3C3 RASSF1 PRKAG1 CCAR1 ATG4C MAP3K15 KIF5B

2.28e-064371441120562859
Pubmed

CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks.

PIK3C2B PIK3C3 PIK3CD

2.40e-067144318755982
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25 ERVK-11

2.74e-0694144621542922
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

CCNJL SLK ABR INTS1 AIP CBLB SPECC1 BLK CCNE1 EFNA1 CDC16 RASSF1 PRKAG1 DDX60L LAS1L

6.11e-069101441536736316
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

DOCK11 ETF1 AK9 USP9Y NEB VPS13D TRANK1 PIK3C2B CCAR1 RP1 DDX24

7.71e-064971441136774506
Pubmed

Hox cofactors in vertebrate development.

HOXD3 PBX1 PBX2

8.17e-0610144316515781
Pubmed

Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells.

PIK3C2B PIK3C3 PIK3CD

8.17e-061014438798481
Pubmed

Expression of HIV-1 nef decreases basal phosphatidyl-inositol 3-kinase activity.

PIK3C2B PIK3C3 PIK3CD

8.17e-061014439247029
Pubmed

The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.

PIK3C2B PIK3C3 PIK3CD

8.17e-061014438636073
Pubmed

Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.

CPT1A PIK3C2B PIK3C3 PIK3CD PRKAG1 KDR

9.73e-06117144618996102
Pubmed

HIV-1 gp120-induced TNF-{alpha} production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways.

PIK3C2B PIK3C3 PIK3CD

1.12e-0511144316081599
Pubmed

Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells.

PIK3C2B PIK3C3 PIK3CD

1.12e-0511144312584329
Pubmed

Ligands of CD4 inhibit the association of phospholipase Cgamma1 with phosphoinositide 3 kinase in T cells: regulation of this association by the phosphoinositide 3 kinase activity.

PIK3C2B PIK3C3 PIK3CD

1.12e-051114439808187
Pubmed

HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells.

PIK3C2B PIK3C3 PIK3CD

1.12e-051114439708406
Pubmed

HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line.

PIK3C2B PIK3C3 PIK3CD

1.12e-0511144310985305
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ARHGEF28 DOCK11 SPATA18 SRGAP2 SPECC1 ANKRD27 VPS13D PIK3C2B PIK3C3 SRGAP1 PRMT5 KIF5B CRYBG3 PPIP5K2

1.48e-058611441436931259
Pubmed

Colony-stimulating factor-1 requires PI3-kinase-mediated metabolism for proliferation and survival in myeloid cells.

PIK3C2B PIK3C3 PIK3CD

1.49e-0512144316514418
Pubmed

HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes.

PIK3C2B PIK3C3 PIK3CD

1.49e-0512144310208934
Pubmed

Recruitment of phosphatidylinositol 3-kinase to CD28 inhibits HIV transcription by a Tat-dependent mechanism.

PIK3C2B PIK3C3 PIK3CD

1.49e-0512144312077252
Pubmed

Down-regulation of LFA-1-mediated T cell adhesion induced by the HIV envelope glycoprotein gp160 requires phosphatidylinositol-3-kinase activity.

PIK3C2B PIK3C3 PIK3CD

1.49e-051214439341793
Pubmed

Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages.

PIK3C2B PIK3C3 PIK3CD

1.49e-0512144312551992
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

ABR RARS1 PTPN23 SRGAP2 CCNE1 PRICKLE3 SUPT6H CDC16 KIF5B LAS1L DDX24 RAVER1

1.53e-056391441223443559
Pubmed

Identification of SRGAP2 as a potential oncogene and a prognostic biomarker in hepatocellular carcinoma.

SRGAP2 SRGAP1

1.70e-052144233984363
Pubmed

SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses.

SRGAP2 SRGAP2C

1.70e-052144227373832
Pubmed

Vps26A and Vps26B subunits define distinct retromer complexes.

VPS26B VPS26A

1.70e-052144221920005
Pubmed

Identification of protein arginine N-methyltransferase 5 (PRMT5) as a novel interacting protein with the tumor suppressor protein RASSF1A.

RASSF1 PRMT5

1.70e-052144226482848
Pubmed

PRMT5 Promotes Cyclin E1 and Cell Cycle Progression in CD4 Th1 Cells and Correlates With EAE Severity.

CCNE1 PRMT5

1.70e-052144234168658
Pubmed

Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation.

PBX1 PBX2

1.70e-05214427910944
Pubmed

The human-specific paralogs SRGAP2B and SRGAP2C differentially modulate SRGAP2A-dependent synaptic development.

SRGAP2C SRGAP2B

1.70e-052144231822692
Pubmed

Pbx1 is required for adult subventricular zone neurogenesis.

PBX1 PBX2

1.70e-052144227226325
Pubmed

Extracellular HIV-1 Tat protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells.

PIK3C2B PIK3C3 PIK3CD

1.93e-051314439394803
Pubmed

HIV-1 Nef in macrophage-mediated disease pathogenesis.

PIK3C2B PIK3C3 PIK3CD

1.93e-0513144323215766
Pubmed

Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line.

PIK3C2B PIK3C3 PIK3CD

2.45e-0514144317157319
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK1 DOCK3 DOCK11

2.45e-0514144312432077
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

VPS33A INTS1 SSB CLOCK ZNF462 SHCBP1 LAS1L PBX2

2.46e-05282144823667531
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DOCK1 DOCK3 ARHGEF28 ABR DOCK11 ARHGAP10 SRGAP2 SSB SRGAP1 SHCBP1 CCAR1 PPIP5K2 VAV2 RAVER1

2.91e-059161441432203420
Pubmed

HIV Nef enhances Tat-mediated viral transcription through a hnRNP-K-nucleated signaling complex.

PIK3C2B PIK3C3 PIK3CD

3.05e-0515144318854243
Pubmed

A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication.

ARHGEF28 CAPN3 CEACAM4 ATP9B CPT1A CDC16 CCAR1

3.67e-05218144719460752
Pubmed

Human immunodeficiency virus type 1 Tat accelerates Kaposi sarcoma-associated herpesvirus Kaposin A-mediated tumorigenesis of transformed fibroblasts in vitro as well as in nude and immunocompetent mice.

PIK3C2B PIK3C3 PIK3CD

3.74e-0516144320019835
Pubmed

Akt/Nox2/NF-κB signaling pathway is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation.

PIK3C2B PIK3C3 PIK3CD

3.74e-0516144321029719
Pubmed

Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders.

PIK3C2B PIK3C3 PIK3CD

3.74e-0516144320818790
Pubmed

HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.

PIK3C2B PIK3C3 PIK3CD

3.74e-0516144316524887
Pubmed

HIV-1 Nef blocks transport of MHC class I molecules to the cell surface via a PI 3-kinase-dependent pathway.

PIK3C2B PIK3C3 PIK3CD

3.74e-0516144311289809
Pubmed

Signaling mechanism of HIV-1 gp120 and virion-induced IL-1beta release in primary human macrophages.

PIK3C2B PIK3C3 PIK3CD

4.53e-0517144318453587
Pubmed

Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways.

PIK3C2B PIK3C3 PIK3CD

4.53e-0517144312960231
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

RARS1 ARHGAP10 CWC27 PHF12 INTS1 HIP1R SRGAP2 SPECC1 WDR11 SUPT6H DROSHA CDC16 PRMT5 CCAR1 TAF5 LAS1L PLS3 INO80E

4.96e-0514971441831527615
Pubmed

The TALE homeodomain protein Pbx2 is not essential for development and long-term survival.

PBX1 PBX2

5.09e-053144215169896
Pubmed

A novel pbx family member expressed during early zebrafish embryogenesis forms trimeric complexes with Meis3 and Hoxb1b.

PBX1 PBX2

5.09e-053144210679934
Pubmed

HOXD3 targeted by miR-203a suppresses cell metastasis and angiogenesis through VEGFR in human hepatocellular carcinoma cells.

HOXD3 KDR

5.09e-053144229402992
Pubmed

A novel mammalian retromer component, Vps26B.

VPS26B VPS26A

5.09e-053144216190980
Pubmed

Homeodomain proteins MEIS1 and PBXs regulate the lineage-specific transcription of the platelet factor 4 gene.

PBX1 PBX2

5.09e-053144212609849
Pubmed

The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver.

PBX1 PBX2

5.09e-053144211468159
Pubmed

Prep1, a novel functional partner of Pbx proteins.

PBX1 PBX2

5.09e-05314429482739
Pubmed

Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system.

SRGAP2 SRGAP1

5.09e-053144219137586
Pubmed

Alzheimer's vulnerable brain region relies on a distinct retromer core dedicated to endosomal recycling.

VPS26B VPS26A

5.09e-053144234965419
Pubmed

Excessive fatty acids activate PRMT5/MDM2/Drosha pathway to regulate miRNA biogenesis and lipid metabolism.

DROSHA PRMT5

5.09e-053144238517158
Pubmed

Identification of a new type of PBX1 partner that contains zinc finger motifs and inhibits the binding of HOXA9-PBX1 to DNA.

ZNF462 PBX1

5.09e-053144217353115
Pubmed

Abr, a Rho-regulating protein, modulates osteoclastogenesis by enhancing lamellipodia formation by interacting with poly(ADP-ribose) glycohydrolase.

ABR PARG

5.09e-053144237507586
Pubmed

METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.

UBR1 ETF1 SSB PRMT5 MAP3K15 KIF5B EDEM1

5.29e-05231144736597993
Pubmed

HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway.

PIK3C2B PIK3C3 PIK3CD

5.42e-0518144312526811
Pubmed

HIV-1 Tat protein induces the production of IDO in human monocyte derived-dendritic cells through a direct mechanism: effect on T cells proliferation.

PIK3C2B PIK3C3 PIK3CD

6.42e-0519144324073214
Pubmed

Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells.

PIK3C2B PIK3C3 PIK3CD

8.75e-052114439446795
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

VPS33A SPECC1 VPS52 NDC80 PIK3C3 CENPI ATG4C

8.90e-05251144729778605
Pubmed

HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes.

PIK3C2B PIK3C3 PIK3CD

1.01e-0422144311154208
Pubmed

Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis.

PIK3C2B PIK3C3

1.02e-044144224098492
Pubmed

Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis.

EFNA1 VAV2

1.02e-044144216782872
Pubmed

Panel-based NGS Reveals Novel Pathogenic Mutations in Autosomal Recessive Retinitis Pigmentosa.

ABCA4 RP1

1.02e-044144226806561
Pubmed

PBX1 acts as terminal selector for olfactory bulb dopaminergic neurons.

PBX1 PBX2

1.02e-044144232156753
Pubmed

Cells recognize osmotic stress through liquid-liquid phase separation lubricated with poly(ADP-ribose).

PARG MAP3K15

1.02e-044144233649309
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-7 ERVK-10

1.02e-044144210469592
Pubmed

srGAP2 arginine methylation regulates cell migration and cell spreading through promoting dimerization.

SRGAP2 PRMT5

1.02e-044144220810653
Pubmed

Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.

PBX1 PBX2

1.02e-044144218723445
Pubmed

A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol.

DOCK1 SRGAP2

1.02e-044144223031429
Pubmed

PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1.

PBX1 PBX2

1.02e-04414421682799
Pubmed

PIK3C2B inhibition improves function and prolongs survival in myotubular myopathy animal models.

PIK3C2B PIK3C3

1.02e-044144227548528
Pubmed

Paralogy mapping: identification of a region in the human MHC triplicated onto human chromosomes 1 and 9 allows the prediction and isolation of novel PBX and NOTCH loci.

PBX1 PBX2

1.02e-04414428661110
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

ABR PHF12 ETF1 SPATA18 SSB CNTLN SUPT6H CDC16 CCAR1 LAS1L DDX24

1.16e-046701441122990118
Pubmed

HIV-1 Tat promotes Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6-induced angiogenesis and tumorigenesis by regulating PI3K/PTEN/AKT/GSK-3β signaling pathway.

PIK3C2B PIK3C3 PIK3CD

1.16e-0423144323301033
Pubmed

Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia.

PIK3C2B PIK3C3 PIK3CD

1.16e-0423144319047410
Pubmed

Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome.

HOXD3 PBX1 PBX2

1.16e-0423144318691704
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

RARS1 ETF1 INTS1 SSB VPS26A ANKRD27 LGALS9 VPS52 PRMT5 EIF2B3 PRKAG1 CCAR1 TAF5 PPIP5K2 LAS1L DDX24

1.20e-0413181441630463901
Pubmed

The DNA sequence, annotation and analysis of human chromosome 3.

TMEM212 OR5AC2 RASSF1 ERVK-11

1.30e-0462144416641997
Pubmed

Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy.

PIK3C2B PIK3C3 PIK3CD

1.50e-0425144317632570
Pubmed

Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120.

PIK3C2B PIK3C3 PIK3CD

1.50e-0425144315689238
Pubmed

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

CPT1A PIK3C2B PIK3C3 PIK3CD PRKAG1 KDR

1.55e-04192144620602615
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

RARS1 VPS13D VPS52 SUPT6H PRMT5 RP1 DDX24

1.64e-04277144730745168
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DOCK1 KIFBP VPS33A INTS1 HIP1R NDC80 CDC16 PRKAG1 LAS1L RAVER1

1.65e-045821441020467437
Pubmed

Identification of novel retromer complexes in the mouse testis.

VPS26B VPS26A

1.69e-045144218656452
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-7 ERVK-18

1.69e-045144212629516
Pubmed

HOX cofactors expression and regulation in the human ovary.

PBX1 PBX2

1.69e-045144218973687
Pubmed

Implication of mouse Vps26b-Vps29-Vps35 retromer complex in sortilin trafficking.

VPS26B VPS26A

1.69e-045144221040701
Pubmed

Transcription factor PBX4 regulates limb development and haematopoiesis in mice.

PBX1 PBX2

1.69e-045144238230761
CytobandEnsembl 112 genes in cytogenetic band chr4q12

SPATA18 CLOCK RASL11B KDR

1.47e-04841444chr4q12
GeneFamilyRho GTPase activating proteins|F-BAR domain containing

SRGAP2 SRGAP2C SRGAP1 SRGAP2B

5.87e-06239541288
GeneFamilyPhosphatidylinositol 3-kinase subunits

PIK3C2B PIK3C3 PIK3CD

7.72e-068953831
GeneFamilyNLR family

NLRP12 NLRP14 NOD1

2.97e-0425953666
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

KIFBP TTC21A TRANK1 CDC16 TTC12

3.50e-04115955769
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP10 SRGAP2 SRGAP1

2.30e-0350953721
CoexpressionERWIN_COHEN_BLOOD_TC_83_AGE_23_48YO_VACCINATED_VS_CONTROL_2DY_UP

TTC21A SRGAP2 LGALS9 SRGAP2C SRGAP2B DDX60L FRMD3

3.14e-061191377M41139
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Ciliated|Control_saline / Treatment groups by lineage, cell group, cell type

TTLL9 TTC21A SPATA18 AK9 ADCY2 LRRC9 RP1 DNAH6

1.77e-07195138860067b5359174f0d1a8b5748bfc0690762e9e740
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

TTC21A TMEM212 SPATA18 AK9 CCDC148 LRRC9 RP1 DNAH6

1.99e-0719813886d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TTC21A TMEM212 SPATA18 AK9 ADCY2 LRRC9 RP1 DNAH6

2.15e-07200138896701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL9 SPATA18 ADCY2 CCDC148 LRRC9 RP1 DNAH6

5.58e-0715513875f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL9 SPATA18 ADCY2 CCDC148 LRRC9 RP1 DNAH6

5.58e-0715513870944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTLL9 TTC21A TMEM212 AK9 LRRC9 RP1 DNAH6

9.98e-071691387fba841664939c771881ba97f14ef1df6635c04ff
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OMD SPECC1 NDC80 RASL11B MAP3K15 LY75 WDR44

1.08e-061711387913bae728b5e653771a27c79a309eb023699f1d0
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OMD SPECC1 NDC80 RASL11B MAP3K15 LY75 WDR44

1.08e-061711387f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2B TMEM101 CCDC148 NALF1 HOXD3 UNC13C FRMD3

2.03e-061881387eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTC21A TMEM212 SPATA18 AK9 TTC12 RP1 DNAH6

2.10e-061891387b55de812043b670cbde810d7d42f45909b6d66ef
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTC21A TMEM212 SPATA18 AK9 TTC12 RP1 DNAH6

2.10e-0618913874e83e49d1265ffe507fdb72924c77c4d1c73f0bd
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRABD2B ARHGEF28 ACP3 CCDC148 NALF1 HOXD3 RP1

2.26e-061911387fe55475ce0666ab5122447a813dc2369e24947b8
ToppCellCOVID-19-kidney-Mito-rich_Distal|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRABD2B ARHGEF28 ACP3 CCDC148 HOXD3 RP1 MAP3K15

2.26e-0619113870965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTLL9 TTC21A TMEM212 SPATA18 AK9 CCDC148 TTC12

2.26e-06191138796483adb97c81208aa513782550acd8a08b63866
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK3 FAT4 TRABD2B CNTLN GUCY1A1 UNC13C PBX1

2.34e-06192138772881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

TTLL9 TMEM212 SPATA18 AK9 CCDC148 RP1 DNAH6

2.34e-061921387354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

USP9Y NEB CBLB BLK POGLUT1 PRICKLE3 SRGAP1

2.77e-0619713878545baf923ddf84c5ce9414a36d810603be52401
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TTLL9 SPATA18 AK9 ADCY2 RP1 DNAH6 PTPN20

3.06e-0620013874992dbf0514d674017315dbd20d91dfec0c608e9
ToppCellSubstantia_nigra-Macroglia-CSF_related|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMEM212 SPATA18 AK9 RP1 DNAH6 PTPN20

4.23e-06136138647663c5d81c766a333207a44fc5b58b07309ee76
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMEM212 SPATA18 AK9 RP1 DNAH6 PTPN20

4.23e-0613613866d2e5b871f4cf8d64e6fe0be666fb3490797c635
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMEM212 SPATA18 AK9 RP1 DNAH6 PTPN20

4.23e-061361386fd4269d194c7c11c6ab4383393a01efab05cbace
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMEM212 SPATA18 AK9 RP1 DNAH6 PTPN20

4.23e-0613613863f6cec8d52c84191f7f6e2dd4dc47524dfd5b21b
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMEM212 SPATA18 AK9 RP1 DNAH6 PTPN20

4.23e-06136138667d736096d6b6ddb4722809557f5e987063b8d23
ToppCellMonocytes-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

ACP3 CEACAM4 NEB SRGAP2B FRMD3

6.80e-06851385e73603d6f22bb56159aa5d1a2695775f038e61d8
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL9 TMEM212 SPATA18 CCDC148 LRRC9 DNAH6

8.64e-0615413864e3bc24043144143842627cacf6f90dda2228910
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL9 TMEM212 SPATA18 CCDC148 LRRC9 DNAH6

8.64e-0615413867556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellBAL-Severe-cDC_4|Severe / Compartment, Disease Groups and Clusters

TTLL9 CEACAM4 CCNE1 RASSF1 TRMT5 PTPN20

1.00e-05158138673f66689ef59f71b14cb7141ca5951cc47fe57c1
ToppCellIIF-Lymphocyte-T_NK-ILC|IIF / Disease, Lineage and Cell Type

TTLL9 KRBA2 NEB ANKRD27 TXNDC16 FER1L5

1.04e-05159138655e4f21548f480ca414c00cbff5ec3b13bafd271
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CCNJL ZNF266 AK9 MFN1 POFUT2 FRMD3

1.19e-0516313866c4d4c55fc8a731acca13c1ba7287f238a9d81e0
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 ADCY2 LRRC9 RP1 DNAH6 FRMD3

1.28e-0516513860c714e852f912b5749de4cb0895406673979b2e6
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 ADCY2 LRRC9 RP1 DNAH6 FRMD3

1.28e-05165138682530f96aaefe28a13bad0474bbad043f127a86c
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ARHGEF28 TTC21A TMEM212 SPATA18 RP1 DNAH6

1.73e-051741386f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ARHGEF28 TTC21A TMEM212 SPATA18 RP1 DNAH6

1.79e-051751386c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCellfacs-Lung-EPCAM-3m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 PTPN23 CBLB PTCHD1 POGLUT1 LY75

1.90e-051771386d445167dae956e641386f84ab3ae9f47c089e09a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2 CBLB SRGAP2C SRGAP1 SRGAP2B FRMD3

2.03e-0517913867394e77e665bf16d3733df91bb12907be460ab44
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPATA18 SRGAP2 CBLB SRGAP2C SRGAP1 SRGAP2B

2.16e-0518113865bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPATA18 SRGAP2 CBLB SRGAP2C SRGAP1 SRGAP2B

2.16e-0518113868e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

TTLL9 TMEM212 SPATA18 CCDC148 RP1 DNAH6

2.23e-051821386fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

TMEM212 SPATA18 CCDC148 LRRC9 RP1 DNAH6

2.23e-051821386e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

SPATA18 SRGAP2 CBLB SRGAP2C RASL11B SRGAP2B

2.30e-051831386fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2 CBLB SRGAP2C SRGAP1 SRGAP2B FRMD3

2.30e-051831386848fc6dd129150897ee339343e83c645b6e779eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2 CBLB SRGAP2C SRGAP1 RASL11B SRGAP2B

2.30e-051831386eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2 CBLB SRGAP2C SRGAP1 RASL11B SRGAP2B

2.30e-0518313867c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTC21A TMEM212 SPATA18 AK9 RP1 DNAH6

2.37e-051841386797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTC21A TMEM212 SPATA18 AK9 RP1 DNAH6

2.37e-05184138677d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

TTLL9 TMEM212 SPATA18 CCDC148 RP1 DNAH6

2.44e-05185138618a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2B ABCA4 MAOA CCDC148 RP1 VAV2

2.52e-051861386f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2B ABCA4 MAOA CCDC148 RP1 VAV2

2.59e-051871386c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

TTLL9 TMEM212 SPATA18 CCDC148 RP1 DNAH6

2.67e-05188138634b11f72ca73153d02edcd09b38983ad1a504659
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRABD2B TMEM101 CCDC148 NALF1 HOXD3 MAP3K15

2.67e-0518813861d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

TTLL9 TTC21A TMEM212 SPATA18 RP1 DNAH6

2.75e-051891386a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ARHGEF28 ARHGAP10 SPECC1 PTCHD1 UNC13C PLS3

2.75e-0518913866b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

TTLL9 TMEM212 SPATA18 CCDC148 RP1 DNAH6

2.75e-051891386b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

TTLL9 TMEM212 SPATA18 CCDC148 RP1 DNAH6

2.75e-05189138627329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

USP9Y CBLB NALF1 GUCY1A1 UNC13C CRYBG3

2.84e-05190138662a3ec1ae0829602b0569cc051210551644f1d46
ToppCellIPF-Myeloid-cDC2|World / Disease state, Lineage and Cell class

CEACAM4 SRGAP2 SPECC1 SRGAP2C SRGAP1 SRGAP2B

2.92e-0519113869fda87fb6bc5b8b6c0214ec909ebbc9f3f65319b
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TTLL9 TMEM212 SPATA18 CCDC148 RP1 DNAH6

2.92e-051911386e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TTLL9 TMEM212 SPATA18 CCDC148 RP1 DNAH6

2.92e-0519113869d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TTLL9 TMEM212 SPATA18 CCDC148 RP1 DNAH6

2.92e-0519113861c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-immature_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CCNJL QRFPR EFNA1 NALF1 SRGAP1 KDR

3.01e-0519213865af3b2b38495e925497c48f605d618bbf970965d
ToppCellBAL-Mild|BAL / Compartment, Disease Groups and Clusters

SRGAP2 LGALS9 SRGAP2C NOD1 TRANK1 DDX60L

3.01e-0519213861a6cbf014d3f7a3fb6f53adab078c4742e7137de
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPATA18 SRGAP2 SRGAP2C SRGAP1 RASL11B SRGAP2B

3.10e-0519313863eaa0461618582a1754400624350d269d24e750a
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TRABD2B NALF1 GUCY1A1 SRGAP1 UNC13C VAV2

3.19e-05194138635f132cc38ac133be01834ed0946188aa0757eb4
ToppCellIPF-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

CEACAM4 SRGAP2 SPECC1 SRGAP2C SRGAP1 SRGAP2B

3.19e-051941386accf4b7b09e2048f2e47a52201e0158684dda8fe
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CEACAM4 SRGAP2 SPECC1 SRGAP2C SRGAP1 SRGAP2B

3.19e-051941386bde6830a281f7cd7fd1733e40a41ddd2673ba88e
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTLL9 TTC21A AK9 LRRC9 RP1 DNAH6

3.47e-05197138674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FAT4 MAOA CBLB NALF1 GUCY1A1 UNC13C

3.47e-05197138611a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TTC21A SPATA18 AK9 ADCY2 RP1 DNAH6

3.67e-05199138615f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ABR DOCK11 SRGAP2 SRGAP2C SRGAP1 SRGAP2B

3.78e-052001386a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ABR DOCK11 SRGAP2 SRGAP2C SRGAP1 SRGAP2B

3.78e-052001386dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ABR DOCK11 SRGAP2 SRGAP2C SRGAP1 SRGAP2B

3.78e-0520013863bba5219453322198e8fdb0921d5f8c403598751
ToppCellMS-IIF-Lymphocyte-T/NK-ILC|IIF / Disease, condition lineage and cell class

TTLL9 KRBA2 NEB ANKRD27 PIK3C2B TXNDC16

3.78e-052001386edb0b252e6ff9824908d1ff7d0d42710b00949c8
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ABR DOCK11 SRGAP2 SRGAP2C SRGAP1 SRGAP2B

3.78e-05200138621bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ABR DOCK11 SRGAP2 SRGAP2C SRGAP1 SRGAP2B

3.78e-052001386a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellmLN-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

ARHGAP10 CNTLN CBLB SRGAP2C POGLUT1 LY75

3.78e-0520013863813fa1ee1462ba83fd8b6253070f46f0b063084
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ABR DOCK11 SRGAP2 SRGAP2C SRGAP1 SRGAP2B

3.78e-05200138633036d21c1c82109284473a515c4f890b33fdd5c
ToppCell368C-Epithelial_cells-Epithelial-A_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SRGAP2B RAVER1

5.58e-054138256c7f31259a515be31fc5b9fa42c327bbccab784
ToppCell368C-Epithelial_cells-Epithelial-A_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SRGAP2B RAVER1

5.58e-0541382cc578c54fb84d2827d656d483dc4b4bbeedad3e7
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NLRP12 ABCA4 RFX4 TRANK1 PADI1

7.81e-0514113854aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NLRP12 ABCA4 RFX4 TRANK1 PADI1

7.81e-051411385e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NLRP12 ABCA4 RFX4 TRANK1 PADI1

8.08e-051421385759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCelltumor_Lung-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

TTC21A CEACAM4 PIK3C2B RASL11B FER1L5

9.21e-0514613858b2d104fdb0fdb09410450c6c651e1edb00cae44
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPATA18 LRRC9 RP1 DNAH6 PTPN20

9.82e-051481385d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPATA18 LRRC9 RP1 DNAH6 PTPN20

9.82e-051481385c8e93b87212f55774223caa385859c566fa1981f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TMEM212 ATP9B LGALS9 SRGAP2C SRGAP2B

1.05e-0415013856c39e73a0b05d4b26589f333ce13924e3d373b8d
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPATA18 ADCY2 LRRC9 RP1 DNAH6

1.18e-0415413859ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPATA18 ADCY2 LRRC9 RP1 DNAH6

1.18e-04154138558072ce422d09f2de602580325eaac6c4ec6c136
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CCNJL ARHGEF28 CAPN3 QRFPR GUCY1A1

1.26e-0415613852cd007b423c2395c5ce331902e7f27c805755eb3
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4|Lung / Manually curated celltypes from each tissue

TTLL9 EFNA1 RP1 NALF2 DNAH6

1.50e-04162138591cc14aec8d580cf97a1929bc1acb00fcbcdb57a
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B2|367C / Donor, Lineage, Cell class and subclass (all cells)

ZNF266 AK9 MFN1 GPR174 POFUT2

1.50e-04162138559c0dcb5b51c1803660aeec51b60deceeeaeea66
ToppCelldroplet-Spleen-nan-18m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC21A ACP3 SRGAP1 RASL11B PBX1

1.54e-041631385bc37c5d9f48b16096d5313657563f3ec84028c8c
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF569 CWC27 OMD SHCBP1 CENPI

1.63e-0416513850edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF569 CWC27 OMD SHCBP1 CENPI

1.63e-041651385fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|356C / Donor, Lineage, Cell class and subclass (all cells)

DOCK11 TTC21A INTS1 VPS52 LY75

1.68e-041661385c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTLL9 TMEM212 AK9 RP1 DNAH6

1.78e-041681385fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTLL9 TMEM212 AK9 RP1 DNAH6

1.78e-0416813857edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 OMD CCNE1 NDC80 CENPI

1.83e-041691385e7514956b2e4298222ec443f98b2f5289451786e
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNJL FAT4 MC1R GUCY1A1 SRGAP1

1.83e-04169138587116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTC21A AK9 CCDC148 RP1 DNAH6

1.83e-04169138514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTLL9 TTC21A SPATA18 LRRC9 DNAH6

1.93e-0417113851854a777d9eb9d3fc3ed3632332a6f89ce8131da
DiseaseDrug habituation

DOCK1 SLK WDR11 ZNF606 PBX1

1.84e-041151345C0013170
DiseaseDrug abuse

DOCK1 SLK WDR11 ZNF606 PBX1

1.84e-041151345C0013146
DiseasePrescription Drug Abuse

DOCK1 SLK WDR11 ZNF606 PBX1

1.84e-041151345C4316881
DiseaseSubstance-Related Disorders

DOCK1 SLK WDR11 ZNF606 PBX1

1.84e-041151345C0236969
DiseaseDrug Use Disorders

DOCK1 SLK WDR11 ZNF606 PBX1

1.84e-041151345C0013222
DiseaseDrug Dependence

DOCK1 SLK WDR11 ZNF606 PBX1

1.84e-041151345C1510472
DiseaseSubstance Dependence

DOCK1 SLK WDR11 ZNF606 PBX1

1.84e-041151345C0038580
DiseaseSubstance Use Disorders

DOCK1 SLK WDR11 ZNF606 PBX1

1.84e-041151345C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

DOCK1 SLK WDR11 ZNF606 PBX1

1.84e-041151345C0029231
DiseaseSubstance abuse problem

DOCK1 SLK WDR11 ZNF606 PBX1

1.92e-041161345C0740858
Diseaseprogrammed cell death protein 5 measurement

NLRP12 ANKRD27

2.03e-0451342EFO_0801927
Diseasetax1-binding protein 3 measurement

NLRP12 ASB3

2.03e-0451342EFO_0802120
Diseaseanorexia nervosa

CNTLN NALF1 WDR11 ASB3

2.96e-04701344MONDO_0005351
DiseaseMalignant neoplasm of breast

IL24 ABCA4 MAOA ZNF569 SPATA18 CPT1A ZDHHC4 CCNE1 NLRP14 EFNA1 PRICKLE3 ZNF432 KDR PLS3

3.90e-04107413414C0006142
DiseaseCakut

SRGAP1 PBX1

1.55e-03131342C1968949
Diseaseinterleukin 1 receptor antagonist measurement

NLRP12 TRANK1 ATG4C

1.82e-03531343EFO_0004754
Diseaseresponse to vaccine, cytokine measurement

ARHGAP10 VPS26A BLK PTCHD1

3.05e-031311344EFO_0004645, EFO_0004873
Diseasecarcinoma (implicated_via_orthology)

FAT4 BLK KDR

3.12e-03641343DOID:305 (implicated_via_orthology)
Diseasesystemising measurement

PIK3CD ASB3

4.06e-03211342EFO_0010221
Diseaseneurodegenerative disease (implicated_via_orthology)

UBR1 FAT4 PRKAG1 KIF5B

4.39e-031451344DOID:1289 (implicated_via_orthology)
Diseasesevere acute respiratory syndrome, COVID-19

ARHGEF28 CWC27 SRGAP2 CCDC148 NALF1 UNC13C PBX1

4.42e-034471347EFO_0000694, MONDO_0100096
DiseaseHepatitis

FAT4 CCDC148

4.46e-03221342HP_0012115

Protein segments in the cluster

PeptideGeneStartEntry
IYEIHKEFYDNLCPK

ABR

146

Q12979
KSKEYLIACIEDHNY

CAPZA3

146

Q96KX2
HYFEGVLKCYLHETL

PRKAG1

271

P54619
LYSDANIYCQIDHKA

CEACAM4

226

O75871
LVEHEKYCDQYRFAI

CCDC148

301

Q8NFR7
IQLCLEAYYDNTIFH

CWC27

41

Q6UX04
ESISYQKLYNELHIC

CNTLN

376

Q9NXG0
DLHESTYKQEVYCNI

CRYBG3

2301

Q68DQ2
YLECLVLDKFESYND

ABCA4

516

P78363
YFDQSHCGYLLEKDL

CCAR1

931

Q8IX12
KHCELNSYGFEELSY

FAT4

3971

Q6V0I7
CEVYKLHRETFYLAQ

CCNE1

156

P24864
KECLKEYAHYFLEVT

CCNJL

226

Q8IV13
HLFCLYVVSKYLAVE

CPT1A

656

P50416
YSYLKEICDHQAEQL

SPECC1

626

Q5M775
VLLLGKCYHFKYEDE

ATG4C

41

Q96DT6
EYYEVLDHCSSILNK

AIP

246

O00170
HDLLSDYELKYCFVD

RAVER1

76

Q8IY67
HCIFIDDYLSYHELQ

PADI1

626

Q9ULC6
EEEHLRQILQKYSYC

RASSF1

316

Q9NS23
LEIKYDFLYEKEHIC

QRFPR

186

Q96P65
DDYVLYLLESLHCQE

RFX4

461

Q33E94
AHEDIKYEQACILYN

PTPN23

106

Q9H3S7
AYYDHVAVLLCLVVF

MC1R

181

Q01726
LEFHIKVSYFEIYLD

KIF5B

126

P33176
NEFTCLDDVYHLYNL

LRRC9

726

Q6ZRR7
FDLSYNLNYHKLCSD

MFN1

501

Q8IWA4
DQQICAYLEEKLHIY

ARHGEF28

1226

Q8N1W1
IETLNHEHYECKYVI

MAOA

256

P21397
HEDCVKALVYYDVES

ANKRD27

541

Q96NW4
DVHLVDHCKYKYLFN

POGLUT1

256

Q8NBL1
RQHFYELSLEYVCKL

ARHGAP10

171

A1A4S6
YHTELEKYEQACNEF

PBX1

161

P40424
IYHSELEKYEQACNE

PBX2

171

P40425
AALEAKICHQIEYYF

SSB

11

P05455
CLHKVLFTEQPETYY

INTS1

611

Q8N201
LDYVICHLDLYDSQS

SPATA18

376

Q8TC71
DSLEVCLKYYEHEFV

ATP9B

821

O43861
CLKVAVDGQHLFEYY

LGALS9

316

O00182
NLHFFYLVECYLVDL

DDX60L

61

Q5H9U9
LEAEHHQYIAKCLKY

DDX60L

671

Q5H9U9
DHIKVTQEQYELYCE

CBLB

351

Q13191
FICDYELHELFKEAN

PLS3

31

P13797
KLYPFIYHAVESCAE

PARG

951

Q86W56
KFSDCYIIHYIDDIL

HERVK_113

186

P63132
DRLCLQDLLFKHYCY

NOD1

246

Q9Y239
VADLHLNYEEAVLYC

LY75

826

O60449
VYLFCDDHKLQRYAL

LAS1L

56

Q9Y4W2
YDEFDLVLHKYLQAE

NALF2

261

O75949
LVELEKEFHFNRYLC

HOXD3

206

P31249
FHDCKQKYDLYISIA

GPR174

126

Q9BXC1
KFSDCYIIHYIDDIL

ERVK-7

186

P63135
KLKFLIYEHECFQEE

INO80E

21

Q8NBZ0
VDLLIYQTLCYTHDD

PIK3C2B

401

O00750
LGSHEYIQYCRKFDI

PIK3C2B

441

O00750
IHYFYCEILQLFKIS

OR5AC2

176

Q9NZP5
VQTKEQYHFCYDIVL

PTPN20

396

Q4JDL3
QYHFCYDIVLEVLRK

PTPN20

401

Q4JDL3
ASCHLTELYFEKGEY

ACP3

311

P15309
CQELLVDLIYFYHVG

PRICKLE3

221

O43900
KFSDCYIIHYFDDIL

ERVK-18

186

Q9QC07
ETKGQFLIDHICNYY

FRMD3

51

A2A2Y4
FLIDHICNYYSLLEK

FRMD3

56

A2A2Y4
DAHLYCLKKYIVDFL

EIF2B3

201

Q9NR50
RSLKNEELYHQSYDC

ADCY2

871

Q08462
ANELFYLSHKLVDLY

CDC16

281

Q13042
ELHLAYCLKYEKFSI

ASB3

346

Q9Y575
LCYIEKCHTYTLQEF

DNAH6

331

Q9C0G6
QDCSHLYHYTVKLLF

HIP1R

221

O75146
LEYSLSDEYCKHHFL

DOCK11

1101

Q5JSL3
LHKECDNYTEAAYTL

DOCK1

1226

Q14185
DIHELYVYKCDENST

DOCK3

541

Q8IZD9
QYILYLVEHEEYQLC

EFNA1

66

P20827
LDEDKHFVVALYDYT

BLK

56

P51451
CYLVHTLLEFYLKTV

IL24

106

Q13007
HHSEKEFCSYLQYLE

PRMT5

271

O14744
LSETCKYLYLLFDED

EDEM1

551

Q92611
EYYQSEAEGLLECHK

MARVELD3

176

Q96A59
TKIHCETDEKDFYLY

DDX24

566

Q9GZR7
FLLHFILDFYEKVCD

CENPI

556

Q92674
YEDFIYHFTKLEICN

CAPN3

401

P20807
TSLEHYKFIVDYCEK

KIFBP

571

Q96EK5
YYVHKEELFDILHDT

KRBA2

186

Q6ZNG9
LDLCYNYLHDSLLKD

OMD

191

Q99983
EKTHNNDCYLDYSFV

RP1

281

P56715
HVTSCVYYKETLLND

MAP3K15

236

Q6ZN16
NYNDVYSAFHVLCKE

RASL11B

186

Q9BPW5
QKILDDLFLHTLCDY

RARS1

586

P54136
EYYSGLKHFIECSLD

TAF5

216

Q15542
ALEYHNRIYICENKE

AK9

1751

Q5TCS8
AALYIDKDLEYVHTF

DROSHA

1226

Q9NRR4
YNLELTYEHFKSEEI

TRMT5

171

Q32P41
CDHPNIVKLLDAFYY

SLK

86

Q9H2G2
KYYIHDLSDLIDCCD

SRGAP1

256

Q7Z6B7
FFEYVDILCNKHRLD

SAMD8

26

Q96LT4
YLQLFIYCAEDLHLK

FER1L5

326

A0AVI2
HCKYREDYFVTADQL

AATK

276

Q6ZMQ8
CIDQLLYSQDKHEYY

POFUT2

161

Q9Y2G5
NTYESHLLVCFLKRY

PTCHD1

476

Q96NR3
KFHYIYSCDLDINVQ

PIK3C3

6

Q8NEB9
ACIFYDENTKHYELL

PHF12

841

Q96QT6
KYYIHDLSDLIDQCC

SRGAP2C

266

P0DJJ0
KYYIHDLSDLIDCCD

SRGAP2B

266

P0DMP2
DYHNLLSQCEESYRK

SHCBP1

246

Q8NEM2
DYYHVDDLENLAKCH

CLOCK

311

O15516
KEKHYLTAFYIVECI

PROKR1

316

Q8TCW9
KFSDCYIIHYIDDIL

ERVK-25

186

P63136
SFARDLLNHKYYQDC

SUPT6H

1421

Q7KZ85
TLKHLDSYLADCYDA

VPS52

426

Q8N1B4
CLHIEFEYNKSKYHL

VPS26B

171

Q4G0F5
VEYAHLYFFHCKLVL

TXNDC16

206

Q9P2K2
YEEYHLTLQALDLCL

TMEM212

141

A6NML5
HCLQEVLKDYYTLVD

RBP3

331

P10745
YNKDLEYLGKCHSDL

UNC13C

691

Q8NB66
YTTEDLIKHYNCGDL

TRABD2B

246

A6NFA1
EVFGYCQELELSLHY

ZDHHC4

86

Q9NPG8
KYYIHDLSDLIDQCC

SRGAP2

266

O75044
KFSDCYIIHYIDDIL

ERVK-10

186

P10266
KFSDCYIIHYIDDIL

ERVK-8

186

P63133
CIFYDTEHLKYHTQI

WDR44

716

Q5JSH3
EKNERYYCVLFNDEH

UBR1

221

Q8IWV7
YESYLDCELTKFLLD

PIK3CD

621

O00329
KFSDCYIIHYIDDIL

ERVK-11

186

Q9UQG0
TVIKEYINECDSDYH

USP9Y

856

O00507
ICIQFAEHYLAEKEY

TTC21A

891

Q8NDW8
CSYSEHQEKNDVFLY

ZNF770

611

Q6IQ21
DKHCFELYGYDILID

TTLL9

316

Q3SXZ7
LYEYDLFGKCLEHNF

ZNF569

136

Q5MCW4
EDCLHIEFEYNKSKY

VPS26A

171

O75436
CLFRENHDTFELYIK

ZNF432

121

O94892
YAIKILAICTNSYHE

TTC12

581

Q9H892
QLCYYETKHTEELDS

ZNF462

2331

Q96JM2
YKDFLTLEHLICYSF

KDR

996

P35968
KECYLEGDQTSLYHA

VPS33A

161

Q96AX1
KFDSLLELVEYYQCH

VAV2

736

P52735
LELVEYYQCHSLKES

VAV2

741

P52735
IYDCIKYDVQHNGSL

PPIP5K2

726

O43314
HLSYLAKVLCGYENV

TRANK1

2481

O15050
LLLETSADNQHYYCD

WDR11

1016

Q9BZH6
HTGEKLYEYKECHQI

ZNF606

311

Q8WXB4
YLICVAYSLQHSKED

TMEM101

151

Q96IK0
EAIFLEVKYDDLYHC

VPS13D

4296

Q5THJ4
FECYLYGVDFLTLHK

ZNF266

106

Q14584
YVLHCQGTEEEKILY

ETF1

331

P62495
LCLDKEDDFLHVYYF

GUCY1A1

191

Q02108
QKDINCERYYSFIHL

NLRP12

501

P59046
IQKDAEYENCYVFTH

NLRP14

466

Q86W24
ELFHCLYETQDKAFI

NLRP14

581

Q86W24
EFESVLHKYLQSEEY

NALF1

281

B1AL88
HNKLFLDYTIKCYES

NDC80

221

O14777
CQTLVSDVDYKNYLH

NEB

3101

P20929