Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCA1 SLC29A3 ABCA2 ABCA12 CFTR SLC5A7 NDUFB2 ABCA7 SLC2A10 SLC24A2 SLC23A2 SLC4A8 ABCC5 SLC47A2 SLC16A4 SLC17A1 SLC22A5 SLC25A10 SLC4A10 ABCB11 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

1.17e-1047722025GO:0022804
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA1 ABCA2 ABCA12 CFTR ABCA7 ABCC5 ABCB11 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

2.90e-0910922012GO:0042626
GeneOntologyMolecularFunctionpyrophosphatase activity

NUDT18 ABCA1 ABCA2 ABCA12 CFTR GPN1 MCM5 RGS9 ABCA7 TUBB1 LONP1 NAV2 ALPL DNAH3 RAB25 CILP DNAH2 ABCC5 YTHDC2 RHOT2 MFN1 RRAGA DDX25 ABCB11 RASEF ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

1.35e-0883922030GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

NUDT18 ABCA1 ABCA2 ABCA12 CFTR GPN1 MCM5 RGS9 ABCA7 TUBB1 LONP1 NAV2 ALPL DNAH3 RAB25 CILP DNAH2 ABCC5 YTHDC2 RHOT2 MFN1 RRAGA DDX25 ABCB11 RASEF ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

1.38e-0884022030GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

NUDT18 ABCA1 ABCA2 ABCA12 CFTR GPN1 MCM5 RGS9 ABCA7 TUBB1 LONP1 NAV2 ALPL DNAH3 RAB25 CILP DNAH2 ABCC5 YTHDC2 RHOT2 MFN1 RRAGA DDX25 ABCB11 RASEF ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

1.38e-0884022030GO:0016818
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA1 ABCA2 ABCA12 CFTR GPN1 MCM5 ABCA7 LONP1 NAV2 ALPL DNAH3 DNAH2 ABCC5 YTHDC2 DDX25 ABCB11 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

2.09e-0844122021GO:0016887
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ABCA1 ABCA2 ABCA12 CFTR GPN1 MCM5 RGS9 ABCA7 TUBB1 LONP1 NAV2 ALPL DNAH3 RAB25 DNAH2 ABCC5 YTHDC2 RHOT2 MFN1 RRAGA DDX25 ABCB11 RASEF ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

3.46e-0877522028GO:0017111
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCA1 ABCA2 ABCA12 CFTR NDUFB2 ABCA7 ABCC5 ABCB11 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

9.22e-0817822013GO:0015399
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA1 ABCA2 ABCA12 CFTR ABCA7 ABCC5 ABCB11

1.04e-06492207GO:0140359
GeneOntologyMolecularFunctionATP-dependent activity

ABCA1 ABCA2 MYO1C ABCA12 CFTR GPN1 MCM5 ABCA7 LONP1 NAV2 ALPL DNAH3 DNAH2 ABCC5 YTHDC2 DDX25 ABCB11 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

1.29e-0661422022GO:0140657
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCA1 SLC29A3 ABCA2 ABCA12 CFTR SLC5A7 NDUFB2 ABCA7 SLC22A17 SLC2A10 SLC24A2 KCNAB1 SLC23A2 SFXN4 SLC4A8 ABCC5 KCNG3 SLC47A2 SLC16A4 CLCA2 SLC17A1 SLC22A5 SLC25A10 SLC4A10 ABCB11 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3 DISP1 SLC2A11

2.20e-06118022032GO:0022857
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC5A7 NDUFB2 SLC2A10 SLC24A2 SLC23A2 SLC4A8 SLC47A2 SLC17A1 SLC4A10 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

6.72e-0630122014GO:0022853
GeneOntologyMolecularFunctiontransporter activity

ABCA1 SLC29A3 ABCA2 ABCA12 CFTR SLC5A7 NDUFB2 ABCA7 SLC22A17 SLC2A10 SLC24A2 KCNAB1 SLC23A2 SFXN4 SLC4A8 ABCC5 KCNG3 SLC47A2 SLC16A4 CLCA2 SLC17A1 SLC22A5 SLC25A10 SLC4A10 ABCB11 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3 DISP1 SLC2A11

1.35e-05128922032GO:0005215
GeneOntologyMolecularFunctionsymporter activity

SLC5A7 SLC2A10 SLC24A2 SLC23A2 SLC4A8 SLC16A4 SLC17A1 SLC22A5 SLC4A10

4.40e-051502209GO:0015293
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

4.43e-05362205GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

4.43e-05362205GO:0015662
GeneOntologyMolecularFunctionapolipoprotein A-I receptor activity

ABCA1 ABCA7

1.21e-0422202GO:0034188
GeneOntologyMolecularFunctionP-type calcium transporter activity

ATP2A1 ATP2A2 ATP2A3

2.04e-04112203GO:0005388
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA1 ABCA2 ABCA12 ABCA7

2.39e-04282204GO:0140326
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CFTR SLC5A7 NDUFB2 SLC2A10 SLC24A2 KCNAB1 SLC23A2 SLC4A8 ABCC5 KCNG3 SLC47A2 CLCA2 SLC17A1 SLC25A10 SLC4A10 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

2.88e-0475822020GO:0015318
GeneOntologyMolecularFunctionapolipoprotein receptor activity

ABCA1 ABCA7

3.60e-0432202GO:0030226
GeneOntologyMolecularFunctionsodium,bicarbonate:chloride antiporter activity

SLC4A8 SLC4A10

3.60e-0432202GO:0140892
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC5A7 SLC2A10 SLC24A2 SLC23A2 SLC4A8 SLC47A2 SLC16A4 SLC17A1 SLC22A5 SLC25A10 SLC4A10

4.64e-0429622011GO:0015291
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCC5 SLC47A2 SLC22A5 ABCB11

5.13e-04342204GO:0042910
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

6.03e-04622205GO:0019829
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC5A7 SLC24A2 SLC23A2 SLC4A8 SLC17A1 SLC4A10 ATP12A ATP1A4

6.32e-041712208GO:0015081
GeneOntologyMolecularFunctionfloppase activity

ABCA1 ABCA2 ABCA7

6.65e-04162203GO:0140328
GeneOntologyMolecularFunctioncalcium-dependent ATPase activity

ATP2A1 ATP2A3

7.15e-0442202GO:0030899
GeneOntologyMolecularFunctionsphingolipid floppase activity

ABCA1 ABCA2

7.15e-0442202GO:0046623
GeneOntologyMolecularFunctionpurine-rich negative regulatory element binding

PURA PURB

7.15e-0442202GO:0032422
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

SLC2A10 SLC23A2 ABCB11 SLC2A11

1.16e-03422204GO:0015144
GeneOntologyMolecularFunctionglucokinase activity

HK1 HKDC1

1.18e-0352202GO:0004340
GeneOntologyMolecularFunctionhexokinase activity

HK1 HKDC1

1.18e-0352202GO:0004396
GeneOntologyMolecularFunctionfructokinase activity

HK1 HKDC1

1.18e-0352202GO:0008865
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CFTR SLC5A7 NDUFB2 SLC2A10 SLC24A2 KCNAB1 SLC23A2 SFXN4 SLC4A8 KCNG3 SLC47A2 CLCA2 SLC17A1 SLC4A10 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

1.29e-0379322019GO:0015075
GeneOntologyMolecularFunctioncarbohydrate kinase activity

HK1 NAGK HKDC1

1.52e-03212203GO:0019200
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC5A7 NDUFB2 SLC2A10 SLC24A2 KCNAB1 SLC23A2 SLC4A8 KCNG3 SLC47A2 SLC17A1 SLC4A10 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

1.65e-0362722016GO:0022890
GeneOntologyMolecularFunctionsodium:bicarbonate symporter activity

SLC4A8 SLC4A10

1.76e-0362202GO:0008510
GeneOntologyMolecularFunctionalkaline phosphatase activity

ALPL CILP

1.76e-0362202GO:0004035
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A7 SLC23A2 SLC4A8 SLC17A1 SLC4A10

2.02e-03812205GO:0015370
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC5A7 SLC24A2 KCNAB1 SLC23A2 SLC4A8 KCNG3 SLC17A1 SLC4A10 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

2.03e-0346522013GO:0046873
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC5A7 SLC2A10 SLC23A2 SLC4A8 SLC17A1 SLC4A10

2.06e-031192206GO:0015294
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA1 ABCA2 ABCA12 ABCA7

2.39e-03512204GO:0140303
GeneOntologyMolecularFunctionapolipoprotein receptor binding

ABCA12 PCSK9

2.45e-0372202GO:0034190
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC5A7 NDUFB2 SLC2A10 SLC24A2 KCNAB1 SLC23A2 SLC4A8 KCNG3 SLC47A2 SLC17A1 SLC4A10 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

2.91e-0366422016GO:0008324
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

CFTR SLC4A8 ABCC5 CLCA2 SLC17A1 SLC25A10 SLC4A10

2.93e-031712207GO:0015103
GeneOntologyBiologicalProcesssodium ion transport

CFTR SLC5A7 MAGED2 SLC24A2 SLC23A2 PCSK9 SLC4A8 SLC17A1 SLC22A5 SLC4A10 ATP12A ATP1A4

3.68e-0527521712GO:0006814
GeneOntologyBiologicalProcesstransport across blood-brain barrier

ABCA2 SLC2A10 SLC4A8 ABCC5 SLC22A5 ATP1A4 ATP2A3

3.71e-05872177GO:0150104
GeneOntologyBiologicalProcessvascular transport

ABCA2 SLC2A10 SLC4A8 ABCC5 SLC22A5 ATP1A4 ATP2A3

3.99e-05882177GO:0010232
GeneOntologyBiologicalProcesscellular homeostasis

ABCA2 HK1 ABCA12 CFTR SLC22A17 SLC2A10 SLC24A2 ALPL FOXO3 RAF1 SLC4A8 ICAM1 HKDC1 APLP2 RHOT2 SLC4A10 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3 NNT HCFC1 PCK2 HTT

4.07e-0598121725GO:0019725
GeneOntologyBiologicalProcessmonoatomic ion transport

CFTR SLC5A7 RGS9 SLC22A17 SLC2A10 MAGED2 SLC24A2 KCNAB1 SLC23A2 PCSK9 SFXN4 SLC4A8 CAMK2A ICAM1 ABCC5 TLR9 KCNG3 SLC47A2 CLCA2 SLC17A1 MTOR SLC22A5 SLC25A10 SLC4A10 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3 NNT HTT

4.78e-05137421731GO:0006811
GeneOntologyBiologicalProcessexport across plasma membrane

ABCA1 RGS9 ABCC5 SLC47A2 SLC22A5 ATP12A ATP1A4

4.96e-05912177GO:0140115
GeneOntologyBiologicalProcesschemical homeostasis

ABCA1 ABCA2 HK1 ABCA12 CFTR SLC22A17 SLC24A2 SURF4 ALPL PCSK9 FOXO3 RAF1 SLC4A8 ICAM1 HKDC1 APLP2 NCOR2 RRAGA SLC4A10 ABCB11 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3 NNT HCFC1 PCK2 HTT

5.18e-05124921729GO:0048878
GeneOntologyBiologicalProcessresponse to nitrogen compound

TNIK ABCA1 MYO1C MAP1B CFTR RGS9 ITGA2 LONP1 CARD9 ALPL PCSK9 FOXO3 RAF1 CAD NAGK HDAC5 CAMK2A ICAM1 SHC1 TLR9 FAF1 NCOR2 MTOR AIFM1 LEPROT ATP2A1 ATP2A2 PCK2 HTT

7.15e-05127221729GO:1901698
GeneOntologyBiologicalProcessmonoatomic cation transport

CFTR SLC5A7 RGS9 SLC22A17 SLC2A10 MAGED2 SLC24A2 KCNAB1 SLC23A2 PCSK9 SLC4A8 CAMK2A ICAM1 ABCC5 TLR9 KCNG3 SLC47A2 SLC17A1 SLC22A5 SLC4A10 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3 NNT HTT

8.82e-05115721727GO:0006812
GeneOntologyBiologicalProcesscalcium ion transport from cytosol to endoplasmic reticulum

ATP2A2 ATP2A3

1.10e-0422172GO:1903515
GeneOntologyBiologicalProcessintracellular chemical homeostasis

ABCA2 HK1 ABCA12 CFTR SLC22A17 SLC24A2 FOXO3 RAF1 SLC4A8 ICAM1 HKDC1 APLP2 SLC4A10 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3 NNT HCFC1 PCK2 HTT

1.26e-0486621722GO:0055082
GeneOntologyBiologicalProcessmetal ion transport

CFTR SLC5A7 RGS9 SLC22A17 MAGED2 SLC24A2 KCNAB1 SLC23A2 PCSK9 SLC4A8 CAMK2A ICAM1 ABCC5 TLR9 KCNG3 SLC17A1 SLC22A5 SLC4A10 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3 HTT

1.47e-04100021724GO:0030001
GeneOntologyBiologicalProcessregulation of mitochondrial membrane permeability involved in apoptotic process

CHCHD10 CAMK2A RHOT2 PPM1K STPG1

1.61e-04492175GO:1902108
GeneOntologyCellularComponentmitochondrial membrane

CHCHD10 SLC29A3 HK1 REEP1 ABCA12 GCDH SUCLG1 NDUFB2 CKMT2 IFI27L1 VPS13A TMEM65 SDHA ALPL FOXO3 SFXN4 RAF1 HKDC1 RHOT2 IFI27 SIRT4 MFN1 PLAAT3 TMEM242 GCAT MTOR AIFM1 SLC25A10 MRPS23 NNT

7.98e-0986621830GO:0031966
GeneOntologyCellularComponentmitochondrial envelope

CHCHD10 SLC29A3 HK1 REEP1 ABCA12 GCDH SUCLG1 NDUFB2 CKMT2 IFI27L1 VPS13A TMEM65 SDHA ALPL FOXO3 SFXN4 RAF1 HKDC1 RHOT2 IFI27 SIRT4 MFN1 PLAAT3 TMEM242 GCAT MTOR AIFM1 SLC25A10 MRPS23 NNT

2.56e-0891221830GO:0005740
GeneOntologyCellularComponentorganelle envelope

CHCHD10 SLC29A3 HK1 REEP1 ABCA12 GCDH SUCLG1 NDUFB2 RNF43 CKMT2 IFI27L1 SURF4 VPS13A TMEM65 SDHA ALPL FOXO3 SFXN4 RAF1 HKDC1 RHOT2 IFI27 SIRT4 FAF1 MFN1 PLAAT3 NSMF TMEM242 CLCA2 GCAT MTOR AIFM1 SLC25A10 MRPS23 PRICKLE2 ATP2A3 NNT

2.80e-07143521837GO:0031967
GeneOntologyCellularComponentapical plasma membrane

TNIK CFTR SLC5A7 ABCA7 CPO SLC23A2 SLC4A8 DSG2 ABCC5 TLR9 SLC47A2 SLC17A1 SLC22A5 KNCN SLC4A10 ABCB11 ATP12A

1.51e-0548721817GO:0016324
GeneOntologyCellularComponentbasal part of cell

ABCA1 EPPK1 MYO1C CFTR ITGA2 SLC23A2 SLC4A8 ABCC5 TLR9 CLCA2 SLC22A5 SLC4A10 ABCB11 ATP12A

4.61e-0537821814GO:0045178
GeneOntologyCellularComponentmitochondrial inner membrane

CHCHD10 ABCA12 GCDH SUCLG1 NDUFB2 CKMT2 TMEM65 SDHA SFXN4 RHOT2 SIRT4 MFN1 TMEM242 GCAT AIFM1 SLC25A10 MRPS23 NNT

5.35e-0559321818GO:0005743
GeneOntologyCellularComponentorganelle inner membrane

CHCHD10 ABCA12 GCDH SUCLG1 NDUFB2 CKMT2 TMEM65 SDHA SFXN4 RHOT2 IFI27 SIRT4 MFN1 TMEM242 GCAT AIFM1 SLC25A10 MRPS23 NNT

5.70e-0565221819GO:0019866
GeneOntologyCellularComponentvacuolar membrane

SLC29A3 ABCA2 CFTR WDR81 SLC22A17 SURF4 VPS13A PCSK9 TOM1 RDH14 SPAG9 TLR9 PLAAT3 MTOR RRAGA ZFYVE26

8.95e-0550721816GO:0005774
GeneOntologyCellularComponentplatelet dense tubular network membrane

ATP2A1 ATP2A2 ATP2A3

8.97e-0592183GO:0031095
GeneOntologyCellularComponentbasal plasma membrane

ABCA1 EPPK1 MYO1C CFTR SLC23A2 SLC4A8 ABCC5 TLR9 CLCA2 SLC22A5 SLC4A10 ABCB11 ATP12A

9.39e-0535421813GO:0009925
GeneOntologyCellularComponentlysosomal membrane

SLC29A3 ABCA2 CFTR WDR81 SURF4 VPS13A PCSK9 TOM1 RDH14 SPAG9 TLR9 PLAAT3 MTOR RRAGA ZFYVE26

1.09e-0446221815GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

SLC29A3 ABCA2 CFTR WDR81 SURF4 VPS13A PCSK9 TOM1 RDH14 SPAG9 TLR9 PLAAT3 MTOR RRAGA ZFYVE26

1.09e-0446221815GO:0098852
GeneOntologyCellularComponentapical part of cell

TNIK CFTR SLC5A7 ABCA7 CPO SLC23A2 SLC4A8 DSG2 ABCC5 TLR9 SLC47A2 SLC17A1 SLC22A5 KNCN SLC4A10 ABCB11 ATP12A

1.68e-0459221817GO:0045177
GeneOntologyCellularComponentplatelet dense tubular network

ATP2A1 ATP2A2 ATP2A3

1.74e-04112183GO:0031094
GeneOntologyCellularComponentmitochondrial outer membrane

SLC29A3 HK1 VPS13A FOXO3 RAF1 RHOT2 IFI27 MFN1 MTOR AIFM1

2.31e-0424121810GO:0005741
GeneOntologyCellularComponentbasolateral plasma membrane

ABCA1 EPPK1 CFTR SLC23A2 SLC4A8 ABCC5 TLR9 SLC22A5 SLC4A10 ABCB11 ATP12A

5.65e-0432021811GO:0016323
GeneOntologyCellularComponentdendrite

MAP1B CFTR SLC5A7 MAPK8IP3 SYNGAP1 PURA KCNAB1 KLHL1 SLC4A8 CAMK2A FAT3 APBA2 APLP2 EFNB2 NSMF MTOR SLC4A10 SKOR1 HCFC1 HTT

6.89e-0485821820GO:0030425
GeneOntologyCellularComponentdendritic tree

MAP1B CFTR SLC5A7 MAPK8IP3 SYNGAP1 PURA KCNAB1 KLHL1 SLC4A8 CAMK2A FAT3 APBA2 APLP2 EFNB2 NSMF MTOR SLC4A10 SKOR1 HCFC1 HTT

7.09e-0486021820GO:0097447
GeneOntologyCellularComponentorganelle outer membrane

SLC29A3 HK1 VPS13A FOXO3 RAF1 RHOT2 IFI27 MFN1 MTOR AIFM1

7.27e-0427921810GO:0031968
GeneOntologyCellularComponentouter membrane

SLC29A3 HK1 VPS13A FOXO3 RAF1 RHOT2 IFI27 MFN1 MTOR AIFM1

7.68e-0428121810GO:0019867
GeneOntologyCellularComponentstereocilium membrane

MYO1C ADGRV1

1.58e-0362182GO:0060171
GeneOntologyCellularComponenthippocampal mossy fiber

MAP1B SLC4A8

2.20e-0372182GO:0097457
DomainAAA

ABCA1 ABCA2 ABCA12 CFTR GPN1 ABCA7 LONP1 NAV2 DNAH3 DNAH2 ABCC5 ABCB11

1.15e-0714421612SM00382
DomainAAA+_ATPase

ABCA1 ABCA2 ABCA12 CFTR GPN1 ABCA7 LONP1 NAV2 DNAH3 DNAH2 ABCC5 ABCB11

1.15e-0714421612IPR003593
DomainABC_transporter_CS

ABCA1 ABCA2 ABCA12 CFTR ABCA7 ABCC5 ABCB11

4.80e-07422167IPR017871
DomainATPase_P-typ_TM_dom

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

7.78e-07162165IPR023298
Domain-

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

7.78e-071621651.20.1110.10
DomainATPase_P-typ_cation-transptr_C

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

1.09e-06172165IPR006068
DomainCation_ATPase_C

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

1.09e-06172165PF00689
DomainABC_tran

ABCA1 ABCA2 ABCA12 CFTR ABCA7 ABCC5 ABCB11

1.24e-06482167PF00005
DomainABC_TRANSPORTER_2

ABCA1 ABCA2 ABCA12 CFTR ABCA7 ABCC5 ABCB11

1.24e-06482167PS50893
DomainABC_TRANSPORTER_1

ABCA1 ABCA2 ABCA12 CFTR ABCA7 ABCC5 ABCB11

1.43e-06492167PS00211
DomainCation_ATPase_N

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

1.50e-06182165PF00690
DomainCation_ATPase_N

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

1.50e-06182165SM00831
DomainP-type_ATPase_IIA

ATP2A1 ATP2A2 ATP2A3

1.53e-0632163IPR005782
DomainABC_transporter-like

ABCA1 ABCA2 ABCA12 CFTR ABCA7 ABCC5 ABCB11

1.64e-06502167IPR003439
DomainATPase_P-typ_cation-transptr_N

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

2.01e-06192165IPR004014
DomainABC_A

ABCA1 ABCA2 ABCA12 ABCA7

8.01e-06122164IPR026082
Domain-

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

3.08e-053221653.40.1110.10
Domain-

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

3.08e-053221652.70.150.10
DomainATPase_P-typ_cyto_domN

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

4.83e-05352165IPR023299
DomainATPase_P-typ_P_site

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

5.56e-05362165IPR018303
DomainP_typ_ATPase

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

5.56e-05362165IPR001757
DomainATPASE_E1_E2

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

5.56e-05362165PS00154
Domain-

ABCA1 ABCA2 ABCA12 CFTR GPN1 MCM5 ABCA7 IDNK LONP1 NAV2 CHST3 DNAH3 RAB25 DNAH2 ABCC5 YTHDC2 RHOT2 MFN1 RRAGA DDX25 ABCB11 RASEF

5.66e-05746216223.40.50.300
DomainATPase_P-typ_transduc_dom_A

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

6.37e-05372165IPR008250
DomainE1-E2_ATPase

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

6.37e-05372165PF00122
DomainJIP_LZII

MAPK8IP3 SPAG9

1.33e-0422162IPR032486
DomainJIP_LZII

MAPK8IP3 SPAG9

1.33e-0422162PF16471
DomainP-loop_NTPase

ABCA1 ABCA2 MYO1C ABCA12 CFTR GPN1 MCM5 ABCA7 IDNK LONP1 NAV2 CHST3 DNAH3 RAB25 DNAH2 ABCC5 YTHDC2 RHOT2 MFN1 RRAGA DDX25 ABCB11 RASEF

1.34e-0484821623IPR027417
DomainSUGAR_TRANSPORT_1

SLC22A17 SLC2A10 SLC22A5 SLC2A11

1.54e-04242164PS00216
DomainHydrolase_3

ATP2A1 ATP2A2 ATP2A3

1.72e-04102163PF08282
Domain-

ILVBL SIRT4 NNT

2.35e-041121633.40.50.1220
DomainDHS-like_NAD/FAD-binding_dom

ILVBL SIRT4 NNT

3.11e-04122163IPR029035
DomainPurA

PURA PURB

3.96e-0432162PF04845
DomainPUR

PURA PURB

3.96e-0432162SM00712
DomainPUR-bd_fam

PURA PURB

3.96e-0432162IPR006628
DomainSugar_transporter_CS

SLC22A17 SLC2A10 SLC22A5 SLC2A11

4.85e-04322164IPR005829
DomainHEAT

TOGARAM1 GCN1 MTOR HTT SYMPK

5.50e-04582165IPR000357
DomainMFS_sugar_transport-like

SLC22A17 SLC2A10 SLC22A5 SLC2A11

7.67e-04362164IPR005828
DomainSugar_tr

SLC22A17 SLC2A10 SLC22A5 SLC2A11

7.67e-04362164PF00083
DomainIfi-6-16

IFI27L1 IFI27

7.87e-0442162PF06140
DomainDesmoglein

DSG2 DSG4

7.87e-0442162IPR009123
DomainJNK/Rab-associated_protein-1_N

MAPK8IP3 SPAG9

7.87e-0442162IPR019143
DomainIFI6/IFI27

IFI27L1 IFI27

7.87e-0442162IPR009311
DomainPID_Shc-like

SHC2 SHC1

7.87e-0442162IPR006019
DomainJnk-SapK_ap_N

MAPK8IP3 SPAG9

7.87e-0442162PF09744
DomainHEAT_REPEAT

TOGARAM1 GCN1 HEATR5A MTOR HTT

1.30e-03702165PS50077
DomainHexokinase_2

HK1 HKDC1

1.30e-0352162PF03727
DomainDUF3504

KIAA1958 ZMYM3

1.30e-0352162IPR021893
DomainNa/HCO3_transpt

SLC4A8 SLC4A10

1.30e-0352162IPR003024
DomainHexokinase_BS

HK1 HKDC1

1.30e-0352162IPR019807
DomainHexokinase_C

HK1 HKDC1

1.30e-0352162IPR022673
DomainHexokinase_N

HK1 HKDC1

1.30e-0352162IPR022672
DomainHexokinase_1

HK1 HKDC1

1.30e-0352162PF00349
DomainRH2

MAPK8IP3 SPAG9

1.30e-0352162PS51777
DomainRH1

MAPK8IP3 SPAG9

1.30e-0352162PS51776
DomainDUF3504

KIAA1958 ZMYM3

1.30e-0352162PF12012
DomainHEXOKINASE_2

HK1 HKDC1

1.30e-0352162PS51748
DomainHEXOKINASE_1

HK1 HKDC1

1.30e-0352162PS00378
DomainMFS

SLC22A17 SLC2A10 SLC16A4 SLC17A1 SLC22A5 SLC2A11

1.60e-031082166PS50850
DomainHexokinase

HK1 HKDC1

1.94e-0362162IPR001312
DomainP-type_ATPase_IIC

ATP12A ATP1A4

1.94e-0362162IPR005775
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCA1 SLC29A3 ABCA2 ABCA12 CFTR SLC5A7 PSMB9 ABCA7 SLC22A17 SLC2A10 SLC24A2 PCSK9 RAF1 SLC4A8 CAMK2A ABCC5 SLC47A2 CLCA2 SLC17A1 SLC22A5 SLC25A10 SLC4A10 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3 SLC2A11

1.70e-0873616128M27287
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCA1 SLC29A3 ABCA2 ABCA12 CFTR SLC5A7 ABCA7 SLC22A17 SLC2A10 SLC24A2 PCSK9 RAF1 SLC4A8 CAMK2A ABCC5 CLCA2 SLC17A1 SLC22A5 SLC25A10 SLC4A10 ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

2.17e-0768116125MM14985
PathwayKEGG_ABC_TRANSPORTERS

ABCA1 ABCA2 ABCA12 CFTR ABCA7 ABCC5 ABCB11

5.98e-07441617M11911
PathwayWP_RETT_SYNDROME

HIVEP2 SYNGAP1 FOXG1 HDAC5 NCOR2 HTT

1.67e-05481616M39759
PathwayREACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS

ABCA1 SLC29A3 HK1 ABCA12 CFTR SLC5A7 PSMB9 SLC2A10 SLC22A5 ABCB11

3.58e-0517716110M27476
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

CAMK2A ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

3.69e-05551616M971
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

CAMK2A ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

4.53e-05571616MM15643
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_SERCA

ATP2A1 ATP2A2 ATP2A3

7.85e-0581613M47955
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC29A3 SLC5A7 SLC2A10 SLC24A2 SLC4A8 SLC47A2 SLC17A1 SLC22A5 SLC25A10 SLC4A10 SLC2A11

1.36e-0424916111M5988
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

EPPK1 MYO1C MAP1B CFTR GCDH ITGA2 SORCS1 TUBB1 SERPINB12 SURF4 PURB PZP SDHA CAD ICAM1 MTOR AIFM1 SLC25A10 RASEF ATP2A1 ATP2A2 ATP2A3

2.36e-106472222226618866
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

EPPK1 HK1 MYO1C MAP1B MCM5 ZNF318 CRNKL1 LONP1 GCN1 SDHA CAD PHRF1 YTHDC2 SPAG9 CEBPZ MTOR TLN1 ATP2A2 NNT HCFC1 ZMYM3 SYMPK

2.81e-106532222222586326
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

CHCHD10 HK1 DHRS4L1 GCDH SUCLG1 NDUFB2 PCBD2 CKMT2 LONP1 TMEM65 CTU1 SDHA SFXN4 RDH14 RHOT2 PPM1K MTHFS PNKD MFN1 ISOC2 GCAT AIFM1 SLC25A10 MRPS23 NNT PCK2

4.09e-0910472222618614015
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

CHCHD10 HK1 GCDH SUCLG1 NDUFB2 PCBD2 CKMT2 LONP1 VPS13A TMEM65 SDHA SFXN4 RHOT2 PPM1K MTHFS PNKD IFI27 SIRT4 MFN1 ISOC2 TMEM242 GCAT AIFM1 SLC25A10 MRPS23 NNT PCK2

5.08e-0911362222734800366
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

GCDH RNF43 MAGED2 SURF4 GCN1 ILVBL SDHA SFXN4 FAM234B DSG2 TOM1 DNAH2 RDH14 APLP2 RHOT2 FAF1 ARFGEF3 CEBPZ MTOR TLN1 ATP2A2 PCK2 ZMYM3 SYMPK

1.04e-089422222431073040
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ABCA2 EPPK1 HIVEP2 LRRC24 MCM5 ABCA7 RNF43 MAPK8IP3 SH3TC1 TMEM132A NAV2 GCN1 SDHA FOXO3 PHLDB3 FRAS1 SHC1 RHOT2 NCOR2 MTOR TLN1 ZFYVE26 ATP2A3 HCFC1 HTT SYMPK

1.23e-0811052222635748872
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

HK1 MYO1C MAP1B PSMB9 MCM5 GCDH SUCLG1 MS4A4A LONP1 SURF4 PURA PURB GCN1 ILVBL SDHA ALPL RAF1 CAD TOM1 YTHDC2 RHOT2 ARFGEF3 CEBPZ MTOR AIFM1 TLN1 MRPS23 ATP2A2 HCFC1 PCK2

1.34e-0814402223030833792
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MYO1C ABCA12 GCDH ZNF318 SUCLG1 ABCA7 RNF43 SETDB1 PTPN14 SH3TC1 RTL9 SAP130 ILVBL ALPL RAF1 ING3 DSG2 FAT3 PHRF1 APBA2 YTHDC2 RHOT2 SIK3 NCOR2 GCAT ZMYM3

1.50e-0811162222631753913
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

CHCHD10 HK1 GCDH SUCLG1 NDUFB2 PCBD2 CKMT2 LONP1 TMEM65 CTU1 SDHA SFXN4 RDH14 RHOT2 PPM1K MTHFS PNKD MFN1 GCAT SLC25A10 MRPS23 NNT PCK2

3.41e-089262222320877624
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

NUDT18 HK1 MYO1C MAP1B IQSEC2 ETF1 ITGA2 SUCLG1 DNAJC6 MAPK8IP3 SYNGAP1 USP31 LONP1 SLC24A2 PURA PURB SDHA RAF1 CAD CAMK2A PPFIA4 TOM1 YTHDC2 MTHFS TLN1 PRICKLE2 SLC4A10 ATP2A2 DNPEP

4.34e-0814312222937142655
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

EPPK1 HK1 MYO1C MAP1B GPN1 ETF1 MCM5 SUCLG1 SETDB1 MAGED2 SERPINB12 CZIB GCN1 ILVBL DSG2 TOM1 SHC1 FAF1 NCOR2 MTOR AIFM1 TLN1 SLC25A10 MRPS23 ATP2A2 NNT HCFC1 SYMPK

6.09e-0813672222832687490
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TNIK REEP1 MAP1B IQSEC2 SUCLG1 MAPK8IP3 SYNGAP1 LONP1 PURA PURB KCNAB1 GCN1 SDHA CAD SLC4A8 CAMK2A APBA2 ARFGEF3 ARFGAP2 ISOC2 TENM1 PRICKLE2 SLC4A10 ATP2A2 PCK2

9.04e-0811392222536417873
Pubmed

Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.

EPPK1 HK1 MAP1B CKMT2 SETDB1 CAD HKDC1 AIFM1 SLC25A10 ATP1A4 ATP2A1 ATP2A2

1.10e-072562221235777956
Pubmed

Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.

ABCA1 ABCA2 ABCA12 ABCA7

1.11e-078222424293640
Pubmed

Variability in Streptavidin-Sepharose Matrix Quality Can Significantly Affect Proximity-Dependent Biotinylation (BioID) Data.

MCM5 GCDH ERGIC2 SUCLG1 LONP1 SURF4 ILVBL SDHA SFXN4 FYTTD1 SHC1 AIFM1 SLC25A10 MRPS23 NNT

1.73e-074382221532628020
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

TNIK TOGARAM1 ADGRV1 DSCAML1 NAV2 GCN1 SLC23A2 HDAC5 SPAG9 SIK3 TLN1

2.48e-072252221112168954
Pubmed

The effects of the phenylalanine 256 to valine mutation on the sensitivity of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) Ca2+ pump isoforms 1, 2, and 3 to thapsigargin and other inhibitors.

ATP2A1 ATP2A2 ATP2A3

2.57e-073222316410239
Pubmed

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.

HK1 MYO1C GCDH ERGIC2 MAGED2 GCN1 CAD ICAM1 AIFM1 TLN1 PCK2

3.82e-072352221128378594
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

EPPK1 MYO1C MCM5 CRNKL1 MAGED2 GCN1 SDHA CAD DSG2 SPAG9 CEBPZ AIFM1 TLN1 ATP2A2 PCK2

5.10e-074772221531300519
Pubmed

USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.

MYO1C MCM5 GCDH MAGED2 CRYZL1 PYCR3 SFXN4 CAD RHOT2 FAF1 CEBPZ AIFM1 SLC25A10 ATP2A1 ATP2A2 PCK2

8.42e-075652221633567341
Pubmed

Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis.

ATP2A1 ATP2A2 ATP2A3

1.02e-064222325110346
Pubmed

The nongastric H+-K+-ATPases: molecular and functional properties.

ATP2A1 ATP2A2 ATP2A3

1.02e-064222310362770
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

EPPK1 MYO1C MAGED2 SURF4 VPS13A RAF1 YTHDC2 AIFM1 TLN1 ATP2A2

1.02e-062082221033230847
Pubmed

Biology, structure and mechanism of P-type ATPases.

ATP12A ATP1A4 ATP2A1 ATP2A2 ATP2A3

1.06e-0629222515071553
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TNIK LRRC24 IQSEC2 ETF1 WDR81 ZNF318 DNAJC6 MAPK8IP3 SYNGAP1 PTPRD MAGED2 PURA PURB KCNAB1 FOXG1 CAD SLC4A8 CAMK2A SIK3 NCOR2 MTOR

1.14e-069632222128671696
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ABCA2 EPPK1 HK1 MYO1C ETF1 WDR81 GCN1 CAD RAB25 NAGK MUC19 AIFM1 TLN1 SLC25A10 ATP2A1 ATP2A2 NNT DISP1 DNPEP

1.24e-068072221930575818
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

MYO1C MCM5 ERGIC2 SUCLG1 CRNKL1 LONP1 PTPN14 SURF4 SAP130 PYCR3 ILVBL SDHA ALPL HKDC1 SIK3 NCOR2 GCAT AIFM1 VWA5A LOXL1 TLN1 SLC25A10 MRPS23 ATP2A2 PCK2 DNPEP

2.28e-0614512222630550785
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

ELAPOR2 MAP1B IQSEC2 GCDH ZNF318 DSCAML1 LONP1 PURA PURB GAS2L3 DSG2 ICAM1 TOM1 SHC1 SIK3 PCK2 SYMPK

2.47e-066892221736543142
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

MAP1B ETF1 PTPN13 MAGED2 SURF4 GCN1 SDHA CAD DSG2 COBLL1 ABCC5 YTHDC2 ARFGAP2 AIFM1 TLN1 ATP2A2 HCFC1

3.54e-067082221739231216
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

MYO1C MCM5 ITGA2 ERGIC2 SUCLG1 PTPN13 SURF4 ILVBL SFXN4 FYTTD1 DSG2 ABCC5 APLP2 ARFGAP2 EFNB2 AIFM1 SLC22A5 SLC25A10 ATP2A2 NNT

3.63e-069522222038569033
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

HK1 MYO1C GCDH SUCLG1 LONP1 PTPN14 NDC80 MAGED2 PURB VPS13A SDHA SFXN4 RAF1 CAD SHC1 YTHDC2 SPAG9 RHOT2 MFN1 ARFGEF3 TMEM242 AIFM1 MRPS23 ATP2A2 NNT PCK2

3.95e-0614962222632877691
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

GCDH SUCLG1 LONP1 MAGED2 CZIB GCN1 PYCR3 SDHA NAGK DSG2 SPAG9 FAF1 MFN1 AIFM1 TLN1 ATP2A2 NNT PCK2 HTT

4.21e-068782221937223481
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

EPPK1 HK1 SERPINB12 PURA RAF1 CAMK2A HKDC1 SPAG9 MTOR NNT PCK2

4.67e-063042221132235678
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

ABCA2 SLC2A10 SLC4A8 ABCC5 SLC22A5 ATP1A4 ATP2A3

5.26e-06105222730280653
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

TNIK MAP1B MCM5 PTPN13 MAGED2 GCN1 CAD DSG2 ARFGEF3 HCFC1 SLC2A11

6.16e-063132221138270169
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

ABCA2 MAP1B ABCA12 MCM5 FRAS1 CAD KLHL1 MFN1 AIFM1 SLC22A5 TENM1 DSG4 ATP2A3 HCFC1

6.31e-065132221425798074
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ZNF318 RNF43 PTPN13 PTPN14 GCN1 APBA2 YTHDC2 MTHFS MEIOC TENM1

8.27e-062632221034702444
Pubmed

Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.

GCDH SETDB1 SURF4 VPS13A ILVBL SDHA FAF1 GCAT SLC25A10

8.74e-06209222926389662
Pubmed

Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.

ATP2A1 ATP2A2 ATP2A3

8.81e-067222324786561
Pubmed

Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.

SIK3 SLC17A1 PCSK7

8.81e-067222321149283
Pubmed

The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.

MFN1 ATP2A1 ATP2A2 ATP2A3

1.08e-0522222428890335
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

EPPK1 MYO1C MCM5 PTPN14 MAGED2 GCN1 ILVBL CAD DSG2 MFN1 TLN1 HCFC1

1.12e-053992221237536630
Pubmed

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

HK1 DHRS4L1 GCDH SUCLG1 NDUFB2 LONP1 SDHA SFXN4 ISOC2 GCAT AIFM1 SLC25A10 NNT PCK2

1.17e-055422221414651853
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

EPPK1 MAP1B MCM5 LONP1 PURA GCN1 FRAS1 CAD AIFM1

1.27e-05219222931353912
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

MAP1B ZNF318 PTPN13 PTPN14 GCN1 SAP130 CAD DSG2 SPAG9 CEBPZ TLN1 HCFC1 HTT SYMPK

1.35e-055492221438280479
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

TNIK EPPK1 HK1 MAP1B MCM5 SUCLG1 GCN1 CAD YTHDC2 RHOT2 CEBPZ MTOR MRPS23 ATP2A3 HCFC1 PCK2

1.36e-057042221629955894
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TNIK DNAJC6 USP31 SETDB1 SLC23A2 FRAS1 HDAC5 CAMK2A HEATR5A ARFGEF3 TLN1 ZMYM3

1.37e-054072221212693553
Pubmed

Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides.

ATP2A1 ATP2A2 ATP2A3

1.40e-058222327923914
Pubmed

Gene knockout studies of Ca2+-transporting ATPases.

ATP2A1 ATP2A2 ATP2A3

1.40e-058222310951186
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

ATP2A1 ATP2A2 ATP2A3

1.40e-058222319033399
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

IQSEC2 SUCLG1 TUBB1 SETDB1 LONP1 PTPN13 PTPN14 MAGED2 SURF4 RTL9 GCN1 CHST3 FOXO3 RAF1 PHLDB3 HDAC5 CAMK2A COBLL1 APLP2 SPAG9 MTOR PCK2 DNPEP

1.44e-0513212222327173435
Pubmed

Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism.

MAP1B FOXO3 SLC22A5 PCK2

1.55e-0524222425505152
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

HK1 MYO1C ETF1 MCM5 CRNKL1 LONP1 MAGED2 SERPINB12 SURF4 GCN1 SDHA CAD DSG2 APLP2 YTHDC2 CLCA2 CEBPZ MTOR AIFM1 TLN1 ATP2A2 NNT HCFC1 DNPEP

1.59e-0514252222430948266
Pubmed

Human transcription factor protein interaction networks.

MYO1C ZNF318 PCBD2 SETDB1 LONP1 MAGED2 PURA PURB SAP130 ILVBL CAD ING3 HDAC5 SPAG9 RHOT2 NCOR2 NKX2-4 AIFM1 SLC25A10 MRPS23 ATP2A2 HCFC1 ZMYM3 SYMPK

1.67e-0514292222435140242
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

ETF1 MCM5 CRNKL1 LONP1 MAGED2 GCN1 CAD DSG2 SPAG9 FAF1 MTOR AIFM1 TLN1 ATP2A2 SYMPK

1.72e-056382221533239621
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

SLC29A3 ERGIC2 CHPT1 SURF4 VPS13A SGSM3 SLC23A2 PYCR3 GALNT10 SHC1 RDH14 SPAG9 PNKD SLC47A2 SLC16A4 SLC22A5 SLC4A10 ATP12A ATP2A3 SYMPK

1.76e-0510612222033845483
Pubmed

Proteomic analysis of the mouse liver mitochondrial inner membrane.

ABCA12 GCDH SUCLG1 SDHA RHOT2 GCAT SLC25A10 NNT

1.81e-05175222812865426
Pubmed

The functional interactome landscape of the human histone deacetylase family.

GCN1 SAP130 CAD HDAC5 NCOR2 CEBPZ AIFM1 SLC25A10 ATP2A3 ZMYM3

1.87e-052892221023752268
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

TNIK ITGA2 USP31 PTPN13 PTPN14 SEMA6A SDHA PHLDB3 FYTTD1 DSG2 EFNB2 PCK2

1.91e-054212221236976175
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

HK1 MYO1C MAP1B MCM5 CRNKL1 LONP1 PTPN14 MAGED2 SERPINB12 GCN1 PYCR3 PHLDB3 CAD RHOT2 MTHFS NCOR2 CEBPZ AIFM1 TLN1 MRPS23 ATP2A2 PCK2 ZMYM3

2.09e-0513532222329467282
Pubmed

A micropeptide encoded by a putative long noncoding RNA regulates muscle performance.

ATP2A1 ATP2A2 ATP2A3

2.10e-059222325640239
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CHCHD10 IQSEC2 SLC5A7 DSCAML1 VPS13A SDHA DNAH3 RAB25 DNAH2 MUC19 SPAG9 PLAAT3 AIFM1 TLN1 PRICKLE2 SYMPK

2.34e-057362221629676528
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

EPPK1 MCM5 TUBB1 NDC80 MAGED2 PURA GCN1 FYTTD1 SHC1 YTHDC2 FAF1 NCOR2 TLN1 SYMPK

2.57e-055822221420467437
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ABCA2 HIVEP2 IQSEC2 DSCAML1 MAPK8IP3 SYNGAP1 CRNKL1 SETDB1 PTPN13 PTPRD SGSM3 SDHA ALPL NAGK CAMK2A APBA2 FBXW4 ABCC5 FAF1 PLAAT3 NSMF ATP2A2

2.87e-0512852222235914814
Pubmed

SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166.

ITGA2 SERPINB12 DSG2 MTOR

2.93e-0528222432801337
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

HIVEP2 MAP1B ADGRV1 MAPK8IP3 PTPN13 SHC2 SH3TC1 PURA SEMA6A SAP130 FOXO3 GALNT10 RAB25 FYTTD1 TOM1 PPM1K FAF1 ARFGEF3 NCOR2 EFNB2 TMEM242 RASEF SLC2A11 HTT

3.22e-0514892222428611215
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ABCA2 MAP1B ITGA2 ERGIC2 ABCA7 CHPT1 SURF4 TMEM132A PCSK9 CHST3 FAM234B GALNT10 FRAS1 DSG2 APLP2 RRAGA LOXL1 ATP2A2 ATP2A3 HTT SYMPK

3.24e-0512012222135696571
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

IQSEC2 ITGA2 ERGIC2 SYNGAP1 NDC80 SURF4 TMEM132A TMEM65 ILVBL FOXG1 ONECUT2 ING3 DSG2 MFN1 NCOR2 CEBPZ ATP2A2 NNT HCFC1 ZMYM3 SYMPK

3.32e-0512032222129180619
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

ABCA1 ABCA2 CFTR ABCA7 CHST3 ABCC5 SLC22A5 ABCB11

3.64e-05193222819343046
Pubmed

FOXO3-mTOR metabolic cooperation in the regulation of erythroid cell maturation and homeostasis.

FOXO3 MTOR

4.06e-052222224966026
Pubmed

Calcium/calmodulin-dependent protein kinase II binds to Raf-1 and modulates integrin-stimulated ERK activation.

RAF1 CAMK2A

4.06e-052222212954639
Pubmed

ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease.

ABCA1 ABCA2

4.06e-052222215649702
Pubmed

Preferential incorporation of shorter and less unsaturated acyl phospholipids into high density lipoprotein-like particles in the ABCA1- and ABCA7-mediated biogenesis with apoA-I.

ABCA1 ABCA7

4.06e-052222225665932
Pubmed

Identification of novel phosphorylation sites on postsynaptic density proteins.

SYNGAP1 CAMK2A

4.06e-052222215358237
Pubmed

Sequence of cDNA comprising the human pur gene and sequence-specific single-stranded-DNA-binding properties of the encoded protein.

PURA PURB

4.06e-05222221448097
Pubmed

ABC transporters: from microorganisms to man.

ABCA1 ABCA2

4.06e-05222221282354
Pubmed

Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons.

MAPK8IP3 SPAG9

4.06e-052222233788575
Pubmed

Modulation of B-cell endoplasmic reticulum calcium homeostasis by Epstein-Barr virus latent membrane protein-1.

ATP2A2 ATP2A3

4.06e-052222219650915
Pubmed

RGS9-2--controlled adaptations in the striatum determine the onset of action and efficacy of antidepressants in neuropathic pain states.

RGS9 HDAC5

4.06e-052222226305935
Pubmed

Circadian Gene Circuitry Predicts Hyperactive Behavior in a Mood Disorder Mouse Model.

HIVEP2 CAMK2A

4.06e-052222227028761
Pubmed

PURα Promotes the Transcriptional Activation of PCK2 in Oesophageal Squamous Cell Carcinoma Cells.

PURA PCK2

4.06e-052222233142842
Pubmed

Effect of chronic obstructive pulmonary disease on calcium pump ATPase expression in human diaphragm.

ATP2A1 ATP2A2

4.06e-052222215718407
Pubmed

Inhibitory effect of PCSK9 on Abca1 protein expression and cholesterol efflux in macrophages.

ABCA1 PCSK9

4.06e-052222227940374
Pubmed

Sumoylation of SAP130 regulates its interaction with FAF1 as well as its protein stability and transcriptional repressor function.

SAP130 FAF1

4.06e-052222238172660
Pubmed

Surf4 regulates expression of proprotein convertase subtilisin/kexin type 9 (PCSK9) but is not required for PCSK9 secretion in cultured human hepatocytes.

SURF4 PCSK9

4.06e-052222231676436
Pubmed

Regulation of SERCA pumps expression in diabetes.

ATP2A2 ATP2A3

4.06e-052222225270119
Pubmed

Deletions of PURA, at 5q31, and PURB, at 7p13, in myelodysplastic syndrome and progression to acute myelogenous leukemia.

PURA PURB

4.06e-052222211417483
Pubmed

Regulation of the neuron-specific Ras GTPase-activating protein, synGAP, by Ca2+/calmodulin-dependent protein kinase II.

SYNGAP1 CAMK2A

4.06e-052222214970204
Pubmed

Mechanism of DNA binding and localized strand separation by Pur alpha and comparison with Pur family member, Pur beta.

PURA PURB

4.06e-052222215777841
Pubmed

Sequence of cDNAs encoding components of vascular actin single-stranded DNA-binding factor 2 establish identity to Puralpha and Purbeta.

PURA PURB

4.06e-05222229334258
Pubmed

Training induced decrease in oxygen cost of cycling is accompanied by down-regulation of SERCA expression in human vastus lateralis muscle.

ATP2A1 ATP2A2

4.06e-052222218953100
Pubmed

The adaptor protein p66Shc inhibits mTOR-dependent anabolic metabolism.

SHC1 MTOR

4.06e-052222224550542
Pubmed

SERCA overexpression reduces hydroxyl radical injury in murine myocardium.

ATP2A1 ATP2A2

4.06e-052222216798816
Pubmed

Mechanisms of control of the free Ca2+ concentration in the endoplasmic reticulum of mouse pancreatic β-cells: interplay with cell metabolism and [Ca2+]c and role of SERCA2b and SERCA3.

ATP2A2 ATP2A3

4.06e-052222221885870
Pubmed

Heterogeneity of high density lipoprotein generated by ABCA1 and ABCA7.

ABCA1 ABCA7

4.06e-052222215930518
Pubmed

Inhibition of wild-type p66ShcA in mesangial cells prevents glycooxidant-dependent FOXO3a regulation and promotes the survival phenotype.

FOXO3 SHC1

4.06e-052222217077388
Pubmed

Transcriptomic immaturity inducible by neural hyperexcitation is shared by multiple neuropsychiatric disorders.

HIVEP2 CAMK2A

4.06e-052222230675529
Pubmed

Targeted disruption of the ATP2A1 gene encoding the sarco(endo)plasmic reticulum Ca2+ ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice.

ATP2A1 ATP2A2

4.06e-052222212556521
Pubmed

The cargo receptor SURF4 promotes the efficient cellular secretion of PCSK9.

SURF4 PCSK9

4.06e-052222230251625
Pubmed

K+-Driven Cl-/HCO3- Exchange Mediated by Slc4a8 and Slc4a10.

SLC4A8 SLC4A10

4.06e-052222238674160
InteractionSIRT7 interactions

EPPK1 HK1 MYO1C MAP1B MCM5 ZNF318 CRNKL1 LONP1 GCN1 SDHA RAF1 CAD PHRF1 YTHDC2 SPAG9 CEBPZ MTOR TLN1 ATP2A2 NNT HCFC1 ZMYM3 SYMPK

4.65e-0674421423int:SIRT7
InteractionHK1 interactions

HK1 MAP1B CFTR MAGED2 SDHA RAF1 HKDC1 RHOT2 AIFM1 ATP2A2 NNT HTT

8.10e-0623421412int:HK1
InteractionTPTE interactions

SURF4 GCN1 ILVBL DSG2 SPAG9 RHOT2 TLN1 ATP2A1 ATP2A2

9.89e-061292149int:TPTE
InteractionTES interactions

HK1 MYO1C CFTR GCDH ERGIC2 RNF43 MAGED2 GCN1 CAD NAGK ICAM1 AIFM1 TLN1 PCK2

1.34e-0533221414int:TES
InteractionGIT1 interactions

TNIK SYNGAP1 PTPN13 KLHL1 HDAC5 CAMK2A PPFIA4 ICAM1 MTOR HTT

1.58e-0517221410int:GIT1
InteractionMRAP2 interactions

ABCA2 PTPRD RDH14 APLP2 ISOC2 ATP12A ATP2A1

1.77e-05772147int:MRAP2
InteractionLMBR1L interactions

CFTR GCDH RNF43 MAGED2 SURF4 GCN1 ILVBL SDHA SFXN4 FAM234B DSG2 TOM1 DNAH2 RDH14 APLP2 RHOT2 FAF1 ARFGEF3 CEBPZ MTOR TLN1 ATP2A2 PCK2 ZMYM3 SYMPK

2.59e-0594621425int:LMBR1L
InteractionFAF2 interactions

MAP1B CFTR GCDH ERGIC2 SETDB1 VPS13A GCN1 ILVBL RHOT2 FAF1 MFN1 GCAT AIFM1 SLC25A10 ATP2A1 NNT

2.75e-0545121416int:FAF2
InteractionILK interactions

LONP1 GCN1 ILVBL RAF1 CAD SHC1 RHOT2 PNKD FAF1 MTOR AIFM1 SLC25A10 ATP2A2

3.90e-0531921413int:ILK
InteractionSTK32C interactions

MCM5 GCN1 ILVBL SFXN4 CAD SLC25A10 ATP2A2

3.93e-05872147int:STK32C
InteractionRUVBL1 interactions

MAP1B CFTR GPN1 RNF43 SYNGAP1 RAF1 CAD ING3 HDAC5 SHC1 FBXW4 SPAG9 FAF1 MTOR AIFM1 SLC25A10 HCFC1 HTT

4.50e-0557521418int:RUVBL1
InteractionRASAL1 interactions

SORCS1 SYNGAP1 APLP2 HTT

5.24e-05202144int:RASAL1
InteractionKCTD13 interactions

NUDT18 HK1 MYO1C MAP1B IQSEC2 ETF1 ITGA2 SUCLG1 DNAJC6 MAPK8IP3 SYNGAP1 USP31 LONP1 SLC24A2 PURA PURB SDHA RAF1 CAD CAMK2A PPFIA4 TOM1 APBA2 YTHDC2 MTHFS FAF1 TLN1 PRICKLE2 SLC4A10 ATP2A2 DNPEP

7.34e-05139421431int:KCTD13
InteractionITGB3 interactions

MAP1B SUCLG1 GCN1 RAF1 SHC1 TLN1 NNT HCFC1 HTT

8.74e-051702149int:ITGB3
InteractionGRIN2B interactions

TNIK SYNGAP1 SHC2 SDHA RAF1 CAMK2A APLP2 ATP2A2 HTT

8.74e-051702149int:GRIN2B
InteractionARMCX3 interactions

GPN1 LONP1 RHOT2 PNKD VWA5A ATP2A1 ATP2A3 NNT

8.92e-051332148int:ARMCX3
InteractionSLC25A11 interactions

MAP1B CFTR MS4A4A TMEM65 RAF1 HDAC5 SHC1 FBXW4 FAF1 AIFM1 HTT

9.33e-0525521411int:SLC25A11
GeneFamilySolute carriers

SLC29A3 SLC5A7 SLC22A17 SLC2A10 SLC24A2 SLC23A2 SLC4A8 SLC47A2 SLC16A4 SLC17A1 SLC22A5 SLC25A10 SLC4A10 SLC2A11

2.41e-0639514014752
GeneFamilyATP binding cassette subfamily A

ABCA1 ABCA2 ABCA12 ABCA7

3.25e-06141404805
GeneFamilyATPases Ca2+ transporting

ATP2A1 ATP2A2 ATP2A3

3.69e-05914031209
GeneFamilyDesmosomal cadherins

DSG2 DSG4

1.22e-03714021188
GeneFamilyProprotein convertase subtilisin/kexin family

PCSK9 PCSK7

2.07e-0391402973
CoexpressionMOOTHA_HUMAN_MITODB_6_2002

HK1 GCDH SUCLG1 NDUFB2 CKMT2 LONP1 SDHA RAF1 MFN1 GCAT MTOR AIFM1 SLC25A10 NNT PCK2

4.20e-0643222015M9433
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MID_MESOTHELIAL_CELL

SLC29A3 REEP1 MYO1C PSMB9 BNC1 IFI27L1 SERPINB9 PTPN14 TMEM132A VPS13A NAV2 SEMA6A FRAS1 DSG2 COBLL1 MTHFS PLAAT3 NCOR2 EFNB2 SLC16A4 VWA5A DISP1 ZMYM3

6.19e-0695522023M45680
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_LATE_MESOTHELIAL_CELL

REEP1 PSMB9 BNC1 SERPINB9 PTPN14 TMEM132A VPS13A NAV2 SEMA6A FRAS1 DSG2 COBLL1 ICAM1 MTHFS IFI27 PLAAT3 NCOR2 EFNB2 VWA5A

8.61e-0670422019M45672
CoexpressionSTEIN_ESRRA_TARGETS_UP

HK1 MAP1B SUCLG1 CKMT2 CRNKL1 TMEM132A ILVBL SDHA DSG2 ISOC2 AIFM1 ATP2A3 NNT

2.48e-0538522013M18491
CoexpressionMOOTHA_MITOCHONDRIA

HK1 GCDH SUCLG1 NDUFB2 CKMT2 LONP1 SDHA RAF1 CAD SIRT4 AIFM1 SLC25A10 NNT PCK2

3.06e-0545122014M9577
CoexpressionGSE45365_BCELL_VS_CD8_TCELL_UP

MYO1C DSCAML1 SLC2A10 OTOGL DNAH3 TLR9 SLC16A4 MEIOC RASEF

3.47e-051902209M9991
CoexpressionGSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_UP

ABCA1 MAPK8IP3 BNC1 KCNAB1 ALPL GALNT10 ABCC5 EFNB2 TLN1

4.78e-051982209M3596
CoexpressionGSE18893_CTRL_VS_TNF_TREATED_TREG_2H_UP

CHPT1 PURA PURB SLC23A2 ILVBL FYTTD1 PNKD VWA5A LEPROT

5.17e-052002209M7294
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 CFTR ADGRV1 DSCAML1 SORCS1 PTPRD SLC24A2 OTOGL ONECUT2 FRAS1 FAT3 ARFGEF3 TENM1 ATP1A4

5.65e-13184222142cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 CFTR ADGRV1 DSCAML1 SORCS1 PTPRD SLC24A2 OTOGL ONECUT2 FRAS1 FAT3 ARFGEF3 TENM1 ATP1A4

5.65e-13184222142b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 CFTR ADGRV1 DSCAML1 SORCS1 PTPRD SLC24A2 OTOGL ONECUT2 FRAS1 FAT3 ARFGEF3 TENM1 ATP1A4

5.65e-1318422214ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNIK ELAPOR2 CFTR ADGRV1 PTPN13 ALPL PCSK9 GALNT10 COBLL1 SPAG9 ARFGEF3 SUSD2

3.95e-10199222122dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELAPOR2 CFTR ADGRV1 PTPN13 ALPL PCSK9 COBLL1 SPAG9 ARFGEF3 SUSD2 RASEF

4.57e-09196222117e5addaa844e66f8160e05858c341866a80aed23
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

CFTR ADGRV1 PTPN13 PTPN14 NRXN3 PTPRD NAV2 FRAS1 ABCC5 ARFGEF3

4.96e-08193222102bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TNIK ELAPOR2 CFTR ADGRV1 PTPN13 PTPRD ALPL COBLL1 ARFGEF3 RASEF

4.96e-0819322210f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TNIK ELAPOR2 CFTR ADGRV1 PTPN13 PTPRD ALPL COBLL1 ARFGEF3 RASEF

4.96e-0819322210fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELAPOR2 CFTR PTPN13 ALPL COBLL1 ICAM1 SPAG9 ARFGEF3 SUSD2 RASEF

6.02e-0819722210bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCellLung_Parenchyma-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ELAPOR2 ADGRV1 PTPN13 ALPL RAB25 DSG2 COBLL1 ARFGEF3 SUSD2 RASEF

6.93e-0820022210c2bde99b3bc7a8740441c1a0c1394892b940b857
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ELAPOR2 ADGRV1 PTPN13 ALPL RAB25 DSG2 COBLL1 ARFGEF3 SUSD2 RASEF

6.93e-08200222103ff9abd5e07780a59d5571da906fa15f00a1d5c2
ToppCellParenchyma_Control_(B.)-Epithelial-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ELAPOR2 ADGRV1 PTPN13 ALPL RAB25 DSG2 COBLL1 ARFGEF3 SUSD2 RASEF

6.93e-08200222109970e9bde6aa2ff3aef60dcb065ff15b7463e147
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHCHD10 ABCA12 CFTR ADGRV1 DSCAML1 SORCS1 FRAS1 FAT3 MUC19

1.16e-071602229c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHCHD10 ABCA12 CFTR ADGRV1 DSCAML1 SORCS1 FRAS1 FAT3 MUC19

1.16e-07160222925c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP2 ABCA12 ADGRV1 NRXN3 OTOGL CELF6 FRAS1 FAT3 ATP12A

1.86e-07169222912bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUDT18 ABCA1 IQSEC2 PTPN14 SEMA6A PHLDB3 GAS2L3 APBA2 SIRT4

2.16e-0717222292f1673fcb2356684d60871debb0f159aec553a1c
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUDT18 ABCA1 IQSEC2 PTPN14 SEMA6A PHLDB3 GAS2L3 APBA2 SIRT4

2.16e-071722229b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFTR ADGRV1 PTPN13 NRXN3 PTPRD NAV2 FRAS1 ABCC5 ARFGEF3

3.17e-071802229b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFTR ITGA2 RNF43 PTPN13 NRXN3 RAB25 COBLL1 ARFGEF3 ISOC2

3.32e-0718122290513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ELAPOR2 ITGA2 ADGRV1 RNF43 PTPN13 NRXN3 NAV2 FRAS1 APOL6

4.37e-07187222958d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFTR ITGA2 ADGRV1 RNF43 PTPN13 NRXN3 NAV2 ARFGEF3 RASEF

4.57e-0718822294bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

ELAPOR2 EPPK1 CFTR PTPN13 NRXN3 ALPL COBLL1 HKDC1 ARFGEF3

4.57e-071882229ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellControl-Epithelial-ATII|Control / Disease state, Lineage and Cell class

ELAPOR2 CFTR PTPN13 ALPL RAB25 COBLL1 ARFGEF3 SUSD2 RASEF

5.00e-071902229d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELAPOR2 EPPK1 ALPL PCSK9 COBLL1 HKDC1 SPAG9 PLAAT3 RASEF

5.95e-07194222954975e663ed4414b99b3c9a1aa6335613946470f
ToppCellAT2_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ELAPOR2 CFTR ITGA2 ALPL RAB25 ICAM1 IFI27 SLC16A4 RASEF

6.76e-0719722298b5d4e1c33a57c899c51feb9a6f347232f8910a3
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TNIK ELAPOR2 CFTR ADGRV1 PTPN13 PTPRD ALPL COBLL1 ARFGEF3

7.05e-0719822292e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ELAPOR2 CFTR PTPN13 ALPL RAB25 DSG2 ARFGEF3 SUSD2 RASEF

7.36e-071992229a38a981cffa61c8444a980916de7414e689a1b63
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ELAPOR2 PTPN13 ALPL RAB25 DSG2 COBLL1 ARFGEF3 SUSD2 RASEF

7.67e-07200222935c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ELAPOR2 PTPN13 ALPL RAB25 DSG2 COBLL1 ARFGEF3 SUSD2 RASEF

7.67e-0720022293c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ELAPOR2 PTPN13 ALPL RAB25 DSG2 COBLL1 ARFGEF3 SUSD2 RASEF

7.67e-072002229c905451425d1c24773bb0ca69bcf0309b277d2f1
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ELAPOR2 ADGRV1 OTOGL FRAS1 FAT3 TENM1 ABCB11 ATP12A

1.59e-061622228bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SORCS1 PTPRD OTOGL ZYG11A CAMK2A SLC47A2 SLC17A1 TENM1

2.39e-061712228f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

SLC5A7 ITGA2 DNAJC6 SORCS1 PTPN13 NRXN3 OTOGL GAS2L3

2.60e-0617322286fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ELAPOR2 SLC2A10 ALPL DNAH3 RAB25 DSG2 APBA2 SUSD2

2.72e-061742228110369f6b78de34a6d934b5b47cecd023347bc80
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 HIVEP2 DSCAML1 PTPN14 NAV2 PPFIA4 DDX25 TENM1

2.83e-061752228f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 ABCA1 USP31 SLC24A2 TMEM65 FRAS1 ATP2A2 ATP2A3

3.22e-061782228fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

CFTR ADGRV1 PTPN13 ALPL ARFGEF3 EFNB2 SUSD2 RASEF

3.95e-0618322288e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HIVEP2 USP31 SERPINB9 SEMA6A ROBO4 FYTTD1 ICAM1 EFNB2

4.11e-061842228c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

ELAPOR2 ADGRV1 PTPN13 ALPL RAB25 COBLL1 HKDC1 SUSD2

4.11e-0618422280ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

ELAPOR2 ADGRV1 PTPN13 ALPL RAB25 COBLL1 HKDC1 SUSD2

4.11e-0618422282a8338e94937686a148b5433515700ca0f674058
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

CFTR ADGRV1 PTPN13 NRXN3 PTPRD NAV2 ARFGEF3 RASEF

4.28e-061852228cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellControl-Epithelial-ATII|World / Disease state, Lineage and Cell class

CFTR PTPN13 ALPL RAB25 HKDC1 ARFGEF3 SUSD2 RASEF

4.45e-061862228f4b6e401e19a71beddc73d8a1e08359f7c4025cf
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

TNIK PTPRD VPS13A GAS2L3 SLC47A2 SLC16A4 SLC17A1 SLC22A5

4.63e-061872228d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellE12.5-Epithelial-alveolar_epithelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CHCHD10 CFTR ALPL RAB25 DSG2 ICAM1 HKDC1 PLAAT3

4.82e-061882228c19c89756f2f999e0814f08a89818ef156f6fc69
ToppCellCOPD-Epithelial-ATII|COPD / Disease state, Lineage and Cell class

CFTR ADGRV1 PTPN13 ALPL ARFGEF3 EFNB2 SUSD2 RASEF

4.82e-061882228eb6d79d733b53f64ca615bb777c64ed456866549
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

HIVEP2 NAV2 SEMA6A ALPL ICAM1 SIK3 NCOR2 PRICKLE2

5.01e-06189222846e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

ELAPOR2 ADGRV1 ALPL RAB25 DSG2 ARFGEF3 SUSD2 RASEF

5.01e-061892228926b5fa3064b501a57ba78583e8af33532add455
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

ELAPOR2 ADGRV1 ALPL RAB25 DSG2 ARFGEF3 SUSD2 RASEF

5.01e-0618922286f2322d017b74a1757c81d6e06f50ead8c3dd0cc
ToppCell368C-Epithelial_cells|368C / Donor, Lineage, Cell class and subclass (all cells)

ELAPOR2 ADGRV1 ALPL RAB25 DSG2 ARFGEF3 SUSD2 RASEF

5.21e-061902228459811e88d3001816c2d89034e0921c24918c17f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

TNIK ELAPOR2 CFTR ADGRV1 PTPN13 PTPRD COBLL1 ARFGEF3

5.41e-061912228a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MAP1B NRXN3 PURA CELF6 ARFGEF3 DDX25 TENM1 SLC4A10

5.41e-0619122285d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MAP1B NRXN3 PURA CELF6 ARFGEF3 DDX25 TENM1 SLC4A10

5.41e-06191222873dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGRV1 PTPN13 PTPN14 PTPRD FRAS1 ABCC5 ARFGEF3 PRICKLE2

5.41e-06191222823776c7302cead3881b39127398f3b3e0d27885e
ToppCelldroplet-Skin-nan-21m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK EPPK1 SERPINB12 RAB25 PLAAT3 CLCA2 GCAT SUSD2

5.41e-061912228c5ef34d138cd797029dfefaf4c52d16ba6a76c38
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ELAPOR2 CFTR ADGRV1 PTPN13 ALPL COBLL1 HKDC1 ARFGEF3

5.62e-061922228cc9911e182a289779a2612bc213daae5607689e7
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ELAPOR2 ADGRV1 PTPN13 NAV2 ALPL COBLL1 ARFGEF3 RASEF

6.07e-06194222853f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TNIK ADGRV1 PTPN13 PTPRD ALPL COBLL1 ARFGEF3 RASEF

6.07e-06194222897534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ELAPOR2 ABCA2 DNAJC6 PTPN13 PTPRD SLC24A2 SIK3 ARFGEF3

6.07e-061942228cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA2 RGS9 SLC22A17 PTPRD SLC24A2 FOXG1 FAM234B SIK3

6.07e-061942228ba529c051f248d29f4222f4bc9801ba233859093
ToppCellAT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

ELAPOR2 PTPN13 ALPL GALNT10 COBLL1 ICAM1 SUSD2 RASEF

6.30e-061952228b0cea3f4e59635913d243612f2e8cf4c7b34e726
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HIVEP2 MAP1B SORCS1 PTPRD VPS13A CAMK2A FAT3 SLC4A10

6.30e-0619522282e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 MAP1B SLC24A2 VPS13A NAV2 PCSK9 ATP2A2 ATP2A3

6.30e-0619522287796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell(7)_Epithelial-A_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CFTR PTPN13 ALPL PCSK9 RAB25 COBLL1 ARFGEF3 SUSD2

6.30e-061952228c9a6c65ee18d83bf34a4713d306a6e30db1325c2
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGRV1 PTPN13 PTPN14 PTPRD FRAS1 ABCC5 ARFGEF3 PRICKLE2

6.30e-061952228dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 MAP1B SLC24A2 VPS13A NAV2 PCSK9 ATP2A2 ATP2A3

6.30e-0619522283e519cffa6144a62b06124642a14c9ff39b76554
ToppCellControl-Epithelial|Control / Disease state, Lineage and Cell class

ADGRV1 PTPN13 NAV2 ALPL RAB25 ARFGEF3 SUSD2 RASEF

6.30e-0619522281798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCell356C-Epithelial_cells-Epithelial-B_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

PTPN13 ALPL PCSK9 RAB25 DSG2 HKDC1 ARFGEF3 RASEF

6.79e-06197222806ed8f293d4ee89f14dc2f43d6cae93bbc02508a
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCA2 DNAJC6 USP31 PTPN13 PTPRD SLC24A2 SIK3 ARFGEF3

6.79e-06197222882b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell356C-Epithelial_cells-Epithelial-B_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

PTPN13 ALPL PCSK9 RAB25 DSG2 HKDC1 ARFGEF3 RASEF

6.79e-061972228c115d0a45545ed24259ad88872231bf4d4d389d2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SUCLG1 PTPRD SLC47A2 PLAAT3 ISOC2 SLC16A4 SLC17A1 PCK2

7.04e-06198222872733b6149b797ac11cc108bc80428b77fbbba78
ToppCelldistal-1-Epithelial-Alveolar_Epithelial_Type_2|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ELAPOR2 PTPN13 ALPL RAB25 ICAM1 ARFGEF3 SUSD2 RASEF

7.04e-061982228ce9d6b2a93c7b304414ce1b8b1a09562cf581278
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

ETF1 ITGAX ICAM1 APLP2 SPAG9 IFI27 TLN1 APOL6

7.04e-06198222861ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TNIK ELAPOR2 CFTR ADGRV1 PTPN13 ALPL COBLL1 ARFGEF3

7.04e-061982228f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellFetal_29-31_weeks-Epithelial-club_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFTR ADGRV1 PTPN13 NRXN3 PTPRD NAV2 ARFGEF3 RASEF

7.04e-0619822285fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_2-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFTR PTPN13 ALPL RAB25 HKDC1 ARFGEF3 SUSD2 RASEF

7.04e-061982228de5748c2b66ecc432974cf095ecd241369579f7c
ToppCell5'-Adult-LargeIntestine-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHCHD10 CFTR SUCLG1 NDUFB2 RNF43 RAB25 DSG2 ISOC2

7.04e-06198222808982f9e37591261975ddff9b9a6a59ba836fc0f
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ELAPOR2 RNF43 PTPN13 NRXN3 NAV2 RAB25 ISOC2 SLC2A11

7.04e-061982228aa80315395cb5dffc25927c8a77cd2037aea8772
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SUCLG1 PTPRD SLC47A2 PLAAT3 ISOC2 SLC16A4 SLC17A1 PCK2

7.04e-061982228f23559ce6072e3c323f6791ff95269271b0f7ff1
ToppCell5'-Adult-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHCHD10 CFTR SUCLG1 NDUFB2 RNF43 RAB25 DSG2 ISOC2

7.04e-06198222845a1287dc618a37949978b297e2b782ea80a7f39
ToppCellBiopsy_Other_PF-Epithelial-AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type

ELAPOR2 CFTR PTPN13 ALPL RAB25 ARFGEF3 SUSD2 RASEF

7.31e-0619922289a65acfe9bf500db72142469cf17bf0973540001
ToppCellLPS_IL1RA-Epithelial_alveolar|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ITGA2 RNF43 PTPN13 NRXN3 NAV2 RAB25 ISOC2 SLC2A11

7.31e-0619922285b140ac88ebc25ce397ae577e48f3e271faf46e7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHCHD10 ITGA2 TMEM132A RAB25 DSG2 ISOC2 CLCA2 LOXL1

7.31e-0619922284099df3c052a9536d72ba01492317be7d83a79ad
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ELAPOR2 IQSEC2 RNF43 PTPN13 NRXN3 NAV2 ZYG11A ATP2A1

7.31e-061992228121de4e02585de3a3010398387c523bacf8ce546
ToppCellBiopsy_IPF-Epithelial-Transitional_AT2|Biopsy_IPF / Sample group, Lineage and Cell type

MYO1C ABCA7 ALPL GALNT10 RAB25 ICAM1 SLC16A4 SUSD2

7.31e-06199222883ff8b7e472d1212324c05cc719b746d19e5e23b
ToppCellLPS_only-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor|LPS_only / Treatment groups by lineage, cell group, cell type

RNF43 TUBB1 PTPN13 NRXN3 RAB25 MTHFS ISOC2 SLC2A11

7.31e-0619922287b21447bb39cdba37539a12cb475f463010fc23f
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ITGA2 DSCAML1 RNF43 NRXN3 NAV2 FRAS1 HEATR5A APOL6

7.31e-061992228a270630626df614f8605abddb7dee7c4d74f6149
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ITGA2 ADGRV1 RNF43 NRXN3 NAV2 FRAS1 HEATR5A APOL6

7.58e-0620022288683445ad5b70748c4a1f12eb77d47623085147e
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ELAPOR2 CFTR ADGRV1 PTPN13 ALPL ARFGEF3 SUSD2 RASEF

7.58e-062002228b535323e18d9fb0dde1e0026df142c831e48c29f
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ELAPOR2 CFTR PTPN13 ALPL RAB25 ARFGEF3 SUSD2 RASEF

7.58e-06200222823088edc62bf7d4db890937bfd7925dc316fcc76
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 OTOGL C2CD6 FRAS1 TENM1 ABCB11 ATP12A

8.40e-06145222796712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFTR ITGAX ENO4 HKDC1 STPG1 RASEF DSG4

1.24e-0515422271e32969bee810adaf2d560f0824a16227df513d8
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high|E18.5-samps / Age Group, Lineage, Cell class and subclass

KCNAB1 SEMA6A PCSK9 PHLDB3 ROBO4 KLHL1 PRICKLE2

1.24e-051542227212c340a096a3a9669d1aebd61c045cf1402a868
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRRC24 KIAA1958 FOXG1 PCSK9 FAM234B SLC4A10 RASEF

1.35e-051562227d411116d54add2d4fe649a97ac54cb94c085312f
ToppCellfacs-Heart-Unknown-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REEP1 SORCS1 CKMT2 FRAS1 SLC4A8 KLHL38 SLC17A1

1.41e-0515722278a393eece90fb9a1b7c356736bdb36277261fbd3
ToppCellfacs-Heart-Unknown-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REEP1 SORCS1 CKMT2 FRAS1 SLC4A8 KLHL38 SLC17A1

1.41e-0515722278d30d8e6fae93afcada6bd68799439335cd65b69
ToppCellfacs-Heart-Unknown-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REEP1 SORCS1 CKMT2 FRAS1 SLC4A8 KLHL38 SLC17A1

1.41e-0515722272ac4695d9e4ca8d4ba19c555e9a1d86ac8f398ab
ToppCellVE-CD8-CD4_Treg|VE / Condition, Cell_class and T cell subcluster

ADGRV1 ABCA7 PZP PHLDB3 SHC1 SIRT4 SLC4A10

1.66e-051612227a114f4f75859d9ef900e5146686438d051241429
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

ELAPOR2 PTPN13 OTOGL ALPL PCSK9 RAB25 ARFGEF3

1.87e-051642227d005cfd821b87548b075120bffe65a0be9860463
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ELAPOR2 PTPN13 OTOGL ALPL PCSK9 RAB25 ARFGEF3

1.87e-051642227beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCellmoderate-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TNIK NXPE2 VPS13A ROBO4 SLC4A8 VWA5A ATP1A4

2.02e-051662227c3835b424c63bf11a4e2c47635dc3787fc4a637a
Drugorthovanadate

ABCA1 HK1 MYO1C CFTR SLC2A10 PTPN13 PTPRD ALPL DNAH3 SHC1 ABCC5 AIFM1 ABCB11 ATP2A1 ATP2A2 ATP2A3 SLC2A11 PCK2

2.82e-0743522118CID000061672
Drugverapamil

ABCA1 ABCA2 ABCA12 CFTR ABCA7 CKMT2 NDC80 KCNAB1 ALPL ABCC5 KCNG3 SLC22A5 APOL6 ABCB11 PCSK7 ATP2A1 ATP2A2 ATP2A3

1.57e-0649022118CID000002520
DrugATP-EDC

HK1 ATP2A1 ATP2A2 ATP2A3

1.73e-06102214CID000195647
DrugFludrocortisone acetate [514-36-3]; Up 200; 9.4uM; PC3; HT_HG-U133A

NUDT18 TNIK IQSEC2 DNAJC6 RNF43 CKMT2 NAV2 DNAH3 EFNB2 CLCA2 ATP2A1

3.61e-06196221114342_UP
DrugDubinidine [22964-77-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A

EPPK1 HIVEP2 ZNF318 DNAJC6 SETDB1 PTPN13 MAGED2 SGSM3 SLC23A2 PCSK7 NNT

3.98e-06198221116250_DN
DrugZidovudine

SLC29A3 ABCA7 SLC22A17 SLC2A10 LONP1 SLC23A2 SFXN4 ABCC5 IFI27 MFN1 SLC16A4 SLC22A5 SLC25A10 ABCB11 ATP2A2 SLC2A11 PCK2

1.45e-0552122117ctd:D015215
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A

MYO1C SETDB1 CARD9 SGSM3 GCN1 DNAH3 CAD RHOT2 ARFGAP2 TLN1

2.20e-05195221101561_DN
DrugFusidic acid sodium salt [751-94-0]; Up 200; 7.4uM; PC3; HT_HG-U133A

ABCA1 REEP1 CFTR ABCA7 SGSM3 SLC23A2 FOXG1 ONECUT2 CLCA2 TENM1

2.30e-05196221106754_UP
DrugCyproheptadine hydrochloride [969-33-5]; Up 200; 12.4uM; PC3; HT_HG-U133A

IQSEC2 RNF43 MS4A4A ONECUT2 FAM234B ICAM1 CLCA2 DDX25 ATP2A3 SYMPK

2.30e-05196221106740_UP
Drugimisopasem manganese

SDHA ICAM1 ATP2A1 ATP2A2

2.38e-05182214ctd:C121876
DrugPHA-00745360 [351320-33-7]; Down 200; 1uM; PC3; HT_HG-U133A

MAPK8IP3 PTPN14 NRXN3 KCNAB1 SGSM3 ICAM1 RHOT2 NCOR2 TENM1 HCFC1

2.62e-05199221104562_DN
DrugParbendazole [14255-87-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A

HIVEP2 SETDB1 SEMA6A SGSM3 FOXG1 HDAC5 ICAM1 YTHDC2 ATP2A3 SLC2A11

2.62e-05199221104357_DN
DrugOrlistat; Down 200; 10uM; MCF7; HT_HG-U133A

CFTR MAPK8IP3 TUBB1 PTPN14 CARD9 KCNAB1 SEMA6A HDAC5 CILP ICAM1

2.74e-05200221106415_DN
DiseaseBrody myopathy (implicated_via_orthology)

ATP2A1 ATP2A2 ATP2A3

3.76e-0732143DOID:0050692 (implicated_via_orthology)
DiseaseColorectal Carcinoma

ABCA1 MAP1B ABCA12 CFTR DSCAML1 RNF43 PTPRD SH3TC1 CPO VPS13A C2CD6 PZP DNAH3 CAD ABCC5 TLR9 MFN1 TENM1 ABCB11

1.01e-0670221419C0009402
Diseaseferritin measurement

HK1 RNF43 MS4A4A PTPRD C2CD6 SLC17A1 MRPS23

2.70e-051192147EFO_0004459
Diseaseuric acid measurement

TNIK ABCA1 ZNF318 ADGRV1 DNAH3 FRAS1 FAT3 COBLL1 RDH14 PPM1K PNKD FAF1 SLC17A1 ATP2A2 ZMYM3

4.34e-0561021415EFO_0004761
Diseasehippocampal volume

TNIK EPPK1 MCM5 DSCAML1 PTPRD PURB FOXO3 RDH14 SLC4A10 ABCB11

6.78e-0529721410EFO_0005035
Diseasenervous system disease (implicated_via_orthology)

SKOR1 ATP12A ATP1A4

7.89e-05122143DOID:863 (implicated_via_orthology)
DiseaseStreptozotocin Diabetes

HK1 FOXO3 ICAM1 AIFM1 ATP2A2 ATP2A3

1.40e-041082146C0038433
DiseaseDiabetes Mellitus, Experimental

HK1 FOXO3 ICAM1 AIFM1 ATP2A2 ATP2A3

1.40e-041082146C0011853
DiseaseAlloxan Diabetes

HK1 FOXO3 ICAM1 AIFM1 ATP2A2 ATP2A3

1.40e-041082146C0002152
Diseasehydroquinone sulfate measurement

ABCA2 SORCS1

1.56e-0432142EFO_0021157
Diseasebody mass index, type 2 diabetes mellitus

COBLL1 FAF1 MTOR

1.96e-04162143EFO_0004340, MONDO_0005148
Diseaseproprotein convertase subtilisin/kexin type 7 measurement

DSCAML1 SIK3 PCSK7

2.37e-04172143EFO_0008270
Diseasehigh grade glioma (is_marker_for)

RNF43 SETDB1 CAMK2A MTOR

2.43e-04422144DOID:3070 (is_marker_for)
Diseaseleptin measurement

RGS9 SORCS1 NRXN3 COBLL1 MTHFS

3.14e-04812145EFO_0005000
DiseaseEpilepsy, Cryptogenic

IQSEC2 SYNGAP1 PURA FOXG1 SLC4A10

3.32e-04822145C0086237
DiseaseAwakening Epilepsy

IQSEC2 SYNGAP1 PURA FOXG1 SLC4A10

3.32e-04822145C0751111
DiseaseAura

IQSEC2 SYNGAP1 PURA FOXG1 SLC4A10

3.32e-04822145C0236018
DiseaseTinnitus

ZNF318 ITGAX PTPN13 NDC80 CTU1 SYT16

3.83e-041302146HP_0000360
DiseaseIntellectual Disability

HIVEP2 HK1 MAP1B MAPK8IP3 SYNGAP1 PURA FOXG1 CAMK2A MTOR SLC4A10 HTT

4.55e-0444721411C3714756
Diseasecholesteryl esters to total lipids in IDL percentage

PCSK9 COBLL1 SIK3 PCSK7

4.77e-04502144EFO_0022247
Diseasesoluble transferrin receptor measurement, iron biomarker measurement

SIK3 PCSK7

5.16e-0452142EFO_0004460, EFO_0004461
Diseasecholesterol to total lipids in large LDL percentage

ABCA1 PCSK9 COBLL1 SIK3

7.35e-04562144EFO_0022235
Diseaseallergic bronchopulmonary aspergillosis (is_implicated_in)

CFTR TLR9

7.70e-0462142DOID:13166 (is_implicated_in)
DiseaseDistal spinal muscular atrophy

REEP1 SLC5A7

7.70e-0462142cv:C0393541
DiseaseAbnormal muscle tone

HK1 MAPK8IP3

7.70e-0462142C0852413
Diseaserhegmatogenous retinal detachment

PYCR3 FAT3

7.70e-0462142EFO_0005240
Diseasecomplex trait

ABCA1 GPN1 PCSK9 RAF1 SIK3 ABCB11 PCSK7 LEPROT

8.59e-042712148EFO_0010578
Diseasecholesterol to total lipids in IDL percentage

PCSK9 COBLL1 SIK3 PCSK7

9.55e-04602144EFO_0022233
DiseaseColorectal Neoplasms

ABCA1 ABCA12 CFTR RNF43 PTPRD SH3TC1 ABCC5 ABCB11

9.88e-042772148C0009404
Diseasetransient cerebral ischemia (biomarker_via_orthology)

PTPN13 CAMK2A ICAM1 MTOR AIFM1 HTT

1.03e-031572146DOID:224 (biomarker_via_orthology)
Diseasefamilial hemiplegic migraine (implicated_via_orthology)

ATP12A ATP1A4

1.07e-0372142DOID:0060178 (implicated_via_orthology)
Diseaseserum gamma-glutamyl transferase measurement

TNIK SLC24A2 PURB NAV2 GCN1 FOXO3 SLC4A8 COBLL1 ICAM1 PNKD FAF1 NCOR2 TLN1 SLC25A10 ABCB11 SLC2A11

1.10e-0391421416EFO_0004532
DiseaseEpilepsy

IQSEC2 SYNGAP1 PURA FOXG1 SLC4A10

1.21e-031092145C0014544
Diseasesexual dimorphism measurement

ABCA1 EPPK1 HIVEP2 SETDB1 NRXN3 CARD9 GCN1 FOXO3 HDAC5 COBLL1 RHOT2 SIK3 FAF1 NCOR2 SLC17A1 LOXL1 SLC22A5 PCSK7

1.24e-03110621418EFO_0021796
Diseasepantothenate measurement

ABCA1 CAD

1.42e-0382142EFO_0021034
Diseaseschizophrenia (implicated_via_orthology)

HIVEP2 SYNGAP1 CHST3 MTOR

1.52e-03682144DOID:5419 (implicated_via_orthology)
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

ABCA1 PCSK9 SLC4A8 COBLL1 SIK3 NCOR2 ABCB11 PCSK7

1.74e-033032148EFO_0004612, EFO_0020945
Diseasecystic fibrosis (implicated_via_orthology)

CFTR ABCB11

1.82e-0392142DOID:1485 (implicated_via_orthology)
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

ABCA1 PCSK9 COBLL1 SIK3 NCOR2 PCSK7 HTT

1.88e-032392147EFO_0008317, EFO_0020945
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

ABCA1 PCSK9 COBLL1 SIK3 NCOR2 SLC22A5 PCSK7

2.06e-032432147EFO_0004612, EFO_0020944
DiseaseInflammatory Bowel Diseases

CARD9 ICAM1 MUC19

2.07e-03352143C0021390
Diseasemean reticulocyte volume

HK1 GCDH ZNF318 ABCA7 C20orf203 LONP1 MAGED2 VPS13A ZYG11A CAD DNAH2 FAF1 SLC16A4 MTOR

2.21e-0379921414EFO_0010701
DiseaseMalignant neoplasm of breast

ZNF318 SORCS1 SLC2A10 PTPN14 PTPRD MAGED2 OTOGL CTU1 RAF1 SIK3 STPG1 CLCA2 MTOR MRPS23 TENM1 ZFYVE26 ATP2A3

2.25e-03107421417C0006142
Diseasetheophylline measurement

ITGA2 NAV2

2.27e-03102142EFO_0021180
Diseasemitochondrial complex I deficiency (implicated_via_orthology)

AIFM1 SLC25A10

2.27e-03102142DOID:0060536 (implicated_via_orthology)
Diseaseallergic conjunctivitis (is_marker_for)

ICAM1 TLR9

2.27e-03102142DOID:11204 (is_marker_for)
Diseaselinoleic acid measurement

ABCA1 WDR81 PCSK9 COBLL1 SIK3 ABCB11

2.44e-031862146EFO_0006807
Diseaseheart disease (implicated_via_orthology)

ATP2A1 ATP2A2 ATP2A3

2.63e-03382143DOID:114 (implicated_via_orthology)
Diseasecholine measurement

ABCA1 PCSK9 SIK3 ABCB11 LEPROT

2.63e-031302145EFO_0010116
Diseasepulmonary hypertension (biomarker_via_orthology)

HK1 HDAC5 MFN1 ATP2A2

2.77e-03802144DOID:6432 (biomarker_via_orthology)
DiseaseParkinson disease, disease progression measurement

NXPE2 PTPRD GPR32P1

2.84e-03392143EFO_0008336, MONDO_0005180
DiseaseHypercholesterolemia

ABCA1 PCSK9 ICAM1

2.84e-03392143C0020443
Diseasevery low density lipoprotein cholesterol measurement

ABCA1 DSCAML1 PCSK9 COBLL1 SIK3 NCOR2 PCSK7

3.00e-032602147EFO_0008317
Diseasebody height at birth

HIVEP2 C20orf203 HKDC1

3.05e-03402143EFO_0006784
Diseasegout

ABCA1 CFTR PTPRD MFN1 SLC17A1 ATP1A4

3.16e-031962146EFO_0004274
Diseaseomega-6 polyunsaturated fatty acid measurement

ABCA1 PCSK9 COBLL1 SIK3 SLC22A5 ABCB11

3.24e-031972146EFO_0005680
Diseasehippocampal CA4 volume

TNIK TMEM132A FOXO3

3.27e-03412143EFO_0009396
DiseaseHuntington Disease, Late Onset

AIFM1 HTT

3.29e-03122142C0393574
DiseaseAkinetic-Rigid Variant of Huntington Disease

AIFM1 HTT

3.29e-03122142C0751207
DiseaseJuvenile Huntington Disease

AIFM1 HTT

3.29e-03122142C0751208
Diseasethalamus volume

ADGRV1 NAV2 FOXO3 FAT3

3.44e-03852144EFO_0006935
Diseaselipoprotein measurement, phospholipid measurement

ABCA1 PCSK9 ABCB11 LEPROT

3.44e-03852144EFO_0004639, EFO_0004732
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

PCSK9 COBLL1 SIK3 FAF1 PCSK7 HTT

3.49e-032002146EFO_0004611, EFO_0020945
Diseasemetabolic syndrome

ABCA1 RTL9 PCSK9 COBLL1 SIK3 ABCB11

3.49e-032002146EFO_0000195
Diseaseoral microbiome measurement

FRAS1 APLP2 ATP12A

3.51e-03422143EFO_0801229
Diseasephospholipid measurement

ABCA1 PCSK9 SIK3 ABCB11 LEPROT

3.62e-031402145EFO_0004639
Diseasetriglycerides in large LDL measurement

ABCA1 COBLL1 SIK3

3.75e-03432143EFO_0022319
Diseaseliver cirrhosis (is_implicated_in)

ICAM1 SPAG9 ABCB11

3.75e-03432143DOID:5082 (is_implicated_in)
Diseaseximenoylcarnitine (C26:1) measurement

CZIB SLC22A5

3.87e-03132142EFO_0800543
DiseaseFamilial dilated cardiomyopathy

SDHA RAF1 DSG2

4.00e-03442143C0340427
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

ABCA1 PCSK9 COBLL1 SIK3 NCOR2 SLC22A5 PCSK7

4.16e-032762147EFO_0004612, EFO_0020943
Diseaselipid measurement, lipoprotein measurement

ABCA1 PCSK9 SIK3 LEPROT

4.23e-03902144EFO_0004529, EFO_0004732
Diseasebrain volume measurement

DSCAML1 ENO4 PZP ALPL FOXO3 FRAS1 FAT3 PNKD FAF1 LOXL1 SLC4A10

4.33e-0359521411EFO_0006930
Diseaseobesity (biomarker_via_orthology)

ABCA1 FOXO3 ICAM1 MTOR NNT

4.45e-031472145DOID:9970 (biomarker_via_orthology)
DiseaseLiver Cirrhosis, Experimental

MYO1C PSMB9 SERPINB9 PTPRD TMEM65 C8G NAGK ABCC5 NCOR2 NSMF GCAT SLC17A1 PCK2

4.48e-0377421413C0023893
Diseaseunipolar depression, mood disorder, response to antidepressant

PTPRD SLC4A8

4.50e-03142142EFO_0003761, EFO_0004247, GO_0036276
DiseaseNeurodevelopmental Disorders

IQSEC2 SYNGAP1 PURA FOXG1

4.75e-03932144C1535926
Diseasemiddle cerebral artery infarction (biomarker_via_orthology)

HDAC5 CAMK2A MTOR AIFM1

4.75e-03932144DOID:3525 (biomarker_via_orthology)
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

PCSK9 COBLL1 SLC22A5 PCSK7 HTT

4.85e-031502145EFO_0004611, EFO_0020947
DiseaseCardiomyopathy, Dilated

SDHA RAF1 SLC22A5

5.12e-03482143C0007193
Diseasefasting blood glucose measurement

GPN1 RGS9 SORCS1 SLC24A2 FAT3 ABCB11 LEPROT

5.14e-032872147EFO_0004465
Diseasequinate measurement

ITGA2 LEPROT

5.17e-03152142EFO_0021167
Diseaseanemia (implicated_via_orthology)

SLC4A8 SLC4A10

5.17e-03152142DOID:2355 (implicated_via_orthology)
Diseaselow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

ABCA1 COBLL1 SIK3 ABCB11 PCSK7

5.27e-031532145EFO_0004611, EFO_0020946
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

ABCA1 PCSK9 COBLL1 SIK3 PCSK7 LEPROT HTT

5.53e-032912147EFO_0008317, EFO_0020946
DiseaseCardiomyopathy, Familial Idiopathic

SDHA RAF1 SLC22A5

5.74e-03502143C1449563
Diseasetriglycerides to total lipids in medium LDL percentage

PCSK9 SIK3 SLC22A5

5.74e-03502143EFO_0022334
DiseaseParkinson's disease (implicated_via_orthology)

CHCHD10 DNAJC6 VPS13A FOXO3 RHOT2

5.86e-031572145DOID:14330 (implicated_via_orthology)
Diseasedecreased susceptibility to hepatitis C infection

PTPRD NAV2

5.88e-03162142EFO_0010101
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

CDY2A CDY1

5.88e-03162142C1839071
DiseaseSchizoaffective disorder-bipolar type

NRXN3 PURB

5.88e-03162142EFO_0009965
DiseaseSpermatogenic failure, Y-linked, 2

CDY2A CDY1

5.88e-03162142cv:C1839071
Diseasevitamin C measurement

CHPT1 SLC23A2

5.88e-03162142EFO_0600003
Diseasedual specificity mitogen-activated protein kinase kinase 2 measurement

IFI27L1 IFI27

5.88e-03162142EFO_0008112
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

CDY2A CDY1

5.88e-03162142415000
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

ABCA1 PCSK9 COBLL1 ABCB11

5.92e-03992144EFO_0004611, EFO_0007878
Diseasetriglycerides to total lipids in large LDL percentage

PCSK9 COBLL1 SIK3

6.06e-03512143EFO_0022331
Diseaseaspartate aminotransferase measurement

ABCA1 SETDB1 PTPRD SH3TC1 GCN1 ONECUT2 COBLL1 DNAH2 MUC19 HKDC1 NCOR2 MTOR ABCB11 LEPROT

6.51e-0390421414EFO_0004736
Diseasefatty liver disease (is_marker_for)

ALPL SHC1

6.63e-03172142DOID:9452 (is_marker_for)
DiseaseHuntington Disease

AIFM1 HTT

6.63e-03172142C0020179

Protein segments in the cluster

PeptideGeneStartEntry
ASMATGSATRKGIVV

CDY1

216

Q9Y6F8
TASMATGSATRKGIV

CDY2A

216

Q9Y6F7
GTAMAVSTFRKLDGI

C8G

81

P07360
VAGSTGAGKTSLLMV

CFTR

456

P13569
MTRNSSTIIAFAVGG

DNPEP

76

Q9ULA0
TRQMASSGASGGKID

AIFM1

51

O95831
ATSTAVISGVMSLLG

APOL6

81

Q9BWW8
VFVTTAMGLGTLRNS

ABCA12

1756

Q86UK0
ASGGTVSLIAFTTMA

ERGIC2

31

Q96RQ1
AAVSSVLSGLLGMVA

GSG1

191

Q2KHT4
FKMLTGDTTVTRGDA

ABCA1

1956

O95477
MTRVASLFSGQAVAG

ADGRV1

2486

Q8WXG9
QTSVIFKGTSRMGSL

BNC1

816

Q01954
LALSGATQTRMLTGF

ABCB11

911

O95342
AARSGKLSIGDQIMS

APBA2

606

Q99767
LGMGLVSRSSVSHSV

ARFGAP2

306

Q8N6H7
FSGATMASSRGALVT

SLC25A10

161

Q9UBX3
MASSRGALVTVGQLS

SLC25A10

166

Q9UBX3
RVFSMIIDASGESGL

CARD9

101

Q9H257
SDSAGRVTSATMLLG

CPO

351

Q8IVL8
SDGTLIAMGLSVAVA

DISP1

981

Q96F81
GSRTMAGASSSLVVK

CELF6

196

Q96J87
RAGSLQLSSMSAGNS

COBLL1

341

Q53SF7
GTGKTAAFVLAMLSR

DDX25

146

Q9UHL0
IGIAMGSGTAVAKTA

ATP2A1

716

O14983
IGIAMGSGTAVAKSA

ATP2A3

716

Q93084
GSGTAVAKSAAEMVL

ATP2A3

721

Q93084
AGKTSTFRMVTGDTL

ABCA7

1831

Q8IZY2
TFRMVTGDTLASRGE

ABCA7

1836

Q8IZY2
SFTLMKLRHSSALGG

NAGK

301

Q9UJ70
ASEVMLSTRIGSGSF

RAF1

346

P04049
GVEFSTRTVMLGTAA

RAB25

46

P57735
RASFSVLGDILGSAM

PZP

951

P20742
MSTAALITLVRSGGN

PPM1K

1

Q8N3J5
LAGDAAVGKSSFLMR

RASEF

546

Q8IZ41
KSVLIMDGASAFGTI

CRYZL1

146

O95825
LMRSTVKSSVSLGGI

RGS9

236

O75916
AALRGQSLGLAAMSS

PCBD2

16

Q9H0N5
IDGSGSISSRNFATM

ITGAX

156

P20702
MTFGRSGAASVVLNV

KCNG3

1

Q8TAE7
SGAVMSERVSGLAGS

SPAG9

16

O60271
FGRTSSGKSSVINAM

MFN1

81

Q8IWA4
MAATGTAAAAATGRL

APLP2

1

Q06481
KTARATGASRDMAGA

DSG2

746

Q14126
KSLGEQMAAESRGLS

PHLDB3

291

Q6NSJ2
AVSTAAMTRSSVGAG

HCFC1

1236

P51610
MAAAAVSSAKRSLRG

MTHFS

1

P49914
AISSASIEGLMGRAI

NCOR2

1321

Q9Y618
FTAAGIASSSIAAKM

IFI27

56

P40305
MAGVKALVALSFSGA

LEPROT

1

O15243
GRTKAFSTCGSHLMV

OR11H6

251

Q8NGC7
AGMGSLTGIADAAKS

NKX2-4

161

Q9H2Z4
LESGSDFKSRGMSAA

FRAS1

2721

Q86XX4
SQTGASIGSALAAIM

FRAS1

3896

Q86XX4
AAAVGTGATTAAVMA

MAP1B

796

P46821
TGATTAAVMAAAGIA

MAP1B

801

P46821
ASGTTGGRRVSKALM

MAGED2

196

Q9UNF1
SGSVMSERVSGLAGS

MAPK8IP3

21

Q9UPT6
GKGSSAAGLTASVMR

MCM5

406

P33992
MASEGLAGALASVLA

NUDT18

1

Q6ZVK8
VAATLTAMGLVDRAG

SLC2A10

281

O95528
AFSVSIMRANGLGSI

FNDC7

141

Q5VTL7
RMLGASVATGDVITF

GALNT10

221

Q86SR1
MLAARTGAAGSQISE

KCNAB1

1

Q14722
MGSAADVRFSLGTTT

PPFIA4

511

O75335
GTDIIMGLSSTRAAE

ATP12A

71

P54707
ARAGKSVRLASSGMT

DHRS4L1

11

P0CG22
GAKDSVNGTMARSSL

IQSEC2

1111

Q5JU85
VAVGDSTGMARARTS

LOXL1

131

Q08397
GMLSRATSVLAGLTA

C20orf203

41

Q8NBC4
SGKFTSRRMVSSGLV

C2CD6

586

Q53TS8
GASGAARKRSSTMGT

DSG4

751

Q86SJ6
LMKVGQDASSAGSTR

EFNB2

161

P52799
RLTSTGLTFMDRAGS

FOXG1

291

P55316
LSSGTGAGAITMAAA

ING3

216

Q9NXR8
LAVTFSGGDKMLRSI

PCSK7

371

Q16549
GRDAGVAKGASMRSL

PCSK9

236

Q8NBP7
GVFVGSAMRSESTAA

PCK2

471

Q16822
MRQSGAFLSTSEGLI

ISOC2

151

Q96AB3
LTTEVIAAMGLGAAA

OR51I2

136

Q9H344
IAAMGLGAAARSFIT

OR51I2

141

Q9H344
SAGMTGTTGLSARVT

MUC19

5336

Q7Z5P9
LGGSAMTRGRITTAT

MUC19

6701

Q7Z5P9
LSFVMSRNGSAVGVS

FAM234B

166

A2RU67
STTGMVVGIVAAAAL

NRXN3

1566

Q9Y4C0
RLSGNVSGSFTLMRD

ONECUT2

186

O95948
AMSKLRGAVAAEGAS

PHRF1

901

Q9P1Y6
AGSMAFRALGVATQT

LRRC24

391

Q50LG9
TAMGGSTLFVETSLR

LONP1

771

P36776
MSSVAAKVRAARAFG

NSMF

16

Q6X4W1
TVLVALSAMGFTSVG

IFI27L1

26

Q96BM0
LSAMGFTSVGIAASS

IFI27L1

31

Q96BM0
FTSVGIAASSIAAKM

IFI27L1

36

Q96BM0
VAQKMSVLSGIGSVS

GCN1

356

Q92616
RSKMEAAGFTISGAS

GCAT

331

O75600
TDAIALAMSRDGSSG

PSMB9

176

P28065
ESGSGKGAAMVTAVA

HK1

446

P19367
AASGGRRSATKVMVV

ITGA2

266

P17301
SMTGATGSELGRITF

ELAPOR2

501

A8MWY0
GMAGSGKTTFVQRLT

GPN1

26

Q9HCN4
GMGVSTVTAARILKG

ALPL

61

P05186
RGSMESLALSNATGL

PRICKLE2

541

Q7Z3G6
SGKSSLGMALFRLVE

ABCC5

1231

O15440
GIAMGSGTAVAKTAS

ATP2A2

716

P16615
GAGDSLIAGSAMSKA

CT45A1

41

Q5HYN5
GTGVQRSTAADMAAS

CRNKL1

151

Q9BZJ0
MGTIRTLTGNTFSLA

HTT

791

P42858
FLRASGDMLKGTSSV

HEATR5A

281

Q86XA9
ALLVMGVSGSGKSTV

IDNK

6

Q5T6J7
DAMARLSGTVGVAAV

ILVBL

106

A1L0T0
GAVAMSSAIFTALGI

SLC2A11

156

Q9BYW1
GGSGRQSAAKLSTFM

DNAH3

2436

Q8TD57
QGKFSLRASATGMII

GCDH

251

Q92947
GGSRDSLLEMSTSGV

DSCAML1

2021

Q8TD84
AQMATTAAGVAVGSA

CHCHD10

46

Q8WYQ3
ASSLKGGNLGSMSVR

GAS2L3

356

Q86XJ1
TMAVLSASFVVGVLG

GPR32P1

46

Q8NGA4
TMDAVARSTAGSGRS

CTU1

126

Q7Z7A3
GGSLMSGSSAAKVVL

ARFGEF3

1101

Q5TH69
GNDRTSFLMDSKSGV

FAT3

2436

Q8TDW7
DGRAASSILVGAMFI

DNAJC6

166

O75061
EALRRGNMSSLGFTS

ABCA2

426

Q9BZC7
NTTIRKSGFGGITML

C17orf80

546

Q9BSJ5
RGSLGMNITSSVLAA

MS4A4A

131

Q96JQ5
LNSGFTRLGTDLMTS

FBXW4

76

P57775
VLSGSMAIGAVSLAV

ENO4

231

A6NNW6
VTAVSAGGRSATKMT

IL22RA1

96

Q8N6P7
ISVSKAAAAMGGVFI

KNCN

31

A6PVL3
VVAAAVIMGTAGLST

ICAM1

486

P05362
KMRLLDGGSFTAESS

FAM102B

31

Q5T8I3
DGEVFGMASSALRKS

FAF1

306

Q9UNN5
SLRQGGTLTGKFMST

HDAC5

406

Q9UQL6
ASFVIGIDLRSGAMT

DNAH2

4396

Q9P225
MGVGVSSTASRLGSI

SLC22A5

461

O76082
SVALKGGRGSASMVQ

CZIB

51

Q9NWV4
KAIVSSGTLGDRMAA

CEBPZ

236

Q03701
AGGSKSRLTLSMAVA

PURB

66

Q96QR8
SGLVLGANMTSRSVF

OTOGL

1226

Q3ZCN5
FNMGRAISTGSLASS

PTPN13

901

Q12923
QGLGASTAEISARTM

PTPRD

591

P23468
GRNASLLFATMGTSV

CKMT2

11

P17540
ASKAIGRLAMAGDTF

MTOR

126

P42345
ASAGAAKSMGAIVRG

NNT

241

Q13423
GSRALSNSVSNMGLS

FOXO3

546

O43524
MAGSRLETVGSIFSR

MRPS23

1

Q9Y3D9
EAISSLIMSAVASGG

RTL9

266

Q8NET4
TASGGLSASLMRDTA

RTL9

661

Q8NET4
GLGAVSAAVMSSADS

SLC5A7

336

Q9GZV3
DAGSRLTDVFGSVML

MEIOC

41

A2RUB1
AMGGTVSAVASLVDL

SLC29A3

206

Q9BZD2
ARAFLRSGGMEALTT

SKOR1

31

P84550
LKGMFLSVAAGDRVS

SUSD2

546

Q9UGT4
MAAVVAATALKGRGA

PNKD

1

Q8N490
LLMAGAVASSTFLGV

SFXN4

166

Q6P4A7
EVAGAGAASVMSALT

PLAAT3

41

P53816
ALGAASATLMVGLTV

SLC47A2

581

Q86VL8
NATTGRLSVEMIKGS

SYT16

516

Q17RD7
ATEATMGGKRQVAGS

TMEM132A

786

Q24JP5
SIGFLASVTGAMITS

TMEM170B

76

Q5T4T1
ASVTGAMITSAAVAG

TMEM170B

81

Q5T4T1
AAAGSSTGVMALRFL

SLC22A17

146

Q8WUG5
TSTGDGTAMITRAGL

SDHA

271

P31040
RFLLSESGSTKGAAM

HKDC1

441

Q2TB90
ESGSTKGAAMVTAVA

HKDC1

446

Q2TB90
ARKGLGDMAVSSSVG

SLC24A2

556

Q9UI40
VGNKSDLRSGSSMEA

RHOT2

116

Q8IXI1
STALMAGASGKVTDF

NXPE2

156

Q96DL1
AGVVAGSLAVSVADM

RHBDL3

256

P58872
ADRSATAMSGRGSVL

FAM90A12P

166

A8MX19
ERGRLTSMSTSGFLL

SLC17A1

166

Q14916
LKITFRSMGGAVSAA

EPPK1

231

P58107
SAAGLAMITASGVTV

NAV2

1151

Q8IVL1
LVSRSAGRKSSMDGA

NAV2

1181

Q8IVL1
MLAALNGLSVARVSG

PTPN14

866

Q15678
SLASKARMAGERGAS

RNF43

121

Q68DV7
LGVAMRLAGSLTDVA

SGSM3

351

Q96HU1
LVAGKALSSARMSDA

SIK3

1236

Q9Y2K2
RLLVMTGAGISTESG

SIRT4

56

Q9Y6E7
GTMDSIRSSKLGALF

TUBB1

71

Q9H4B7
LRVTFASGMEIGLSS

TENM1

1726

Q9UKZ4
ASGRVGFVRSSLISM

SH3TC1

351

Q8TE82
LAESRSEGKSMFAGV

SURF4

131

O15260
MAVATAAAVLAALGG

RDH14

1

Q9HBH5
TAAVMAASKGQGALS

REEP1

131

Q9H902
GRISAIESLFGASMT

SLC4A8

506

Q2Y0W8
GAILTTMLATRNFSG

CAMK2A

301

Q9UQM7
GGLRAATMSAVEAAT

PYCR3

251

Q53H96
SAALGMVRLGARSDS

SERPINB12

36

Q96P63
AAAADIATMVSGSSG

SUCLG1

6

P53597
IATMVSGSSGLAAAR

SUCLG1

11

P53597
TVSGGSLLMARAEKS

ROBO4

186

Q8WZ75
GSRMEAEKASTSGLG

SETDB1

1016

Q15047
VIATGDSTVMGRIAS

ATP1A4

266

Q13733
DSTVMGRIASLTSGL

ATP1A4

271

Q13733
DGSSRIMKSNVGVAL

CILP

1101

O75339
LLMATTRTGSSFVGE

CHST3

136

Q7LGC8
MIDAFSRISSGTGDI

CLCA2

476

Q9UQC9
VFMAVGASIAARLGT

CHPT1

141

Q8WUD6
SALAMVSGDGFLVSR

C11orf71

31

Q6IPW1
MNRFGTRLVGATATS

FYTTD1

1

Q96QD9
DSFSGSISREGTLMI

TNIK

891

Q9UKE5
GMAATGVKELAQRSS

VPS13A

1191

Q96RL7
LSTAIARSGMGLTFL

SLC16A4

146

O15374
SSALAMVLLGAKGNT

SERPINB9

36

P50453
LSQGSGSSITAAGMR

SYNGAP1

891

Q96PV0
SAAGVIGMLSAVVAS

SLC23A2

376

Q9UGH3
RFAGMSISIHISTDG

SHC2

216

P98077
RISGASELTATMGEA

TLR9

426

Q9NR96
SSQLAGMNLGSSSVR

TOM1

336

O60784
GITMATAKAVAAGNS

TLN1

2181

Q9Y490
VCTRAGFMSKTQRGS

STPG1

166

Q5TH74
SGSGKTSMRSIIFAN

RRAGA

16

Q7L523
RGSMSSVTKLSGLFG

SEMA6A

696

Q9H2E6
EGRISAIESLFGASM

SLC4A10

536

Q6U841
PRGAAAAAVMSSSKV

SAP130

231

Q9H0E3
MSALTRLASFARVGG

NDUFB2

1

O95178
ASGGTSEFITGKDRM

VWA5A

436

O00534
TSSSFAAAMARLGGA

CAD

1976

P27708
SMAAAALSGLAVRLS

SMIM10

16

Q96HG1
MASGSGDSVTRRSVA

SYMPK

1

Q92797
SIGIILGISTMAAAA

TMEM65

146

Q6PI78
TSATALMVAAGRGFA

YTHDC2

506

Q9H6S0
GAGKHVRSSSMASLR

USP31

1191

Q70CQ4
LEAFAVLASSMGSGK

TOGARAM1

531

Q9Y4F4
ALSLERARGTGASMA

SORCS1

86

Q8WY21
MDTGDTALGQKATSR

HIVEP2

1

P31629
TVAAAGMLAGFITTL

TMEM242

36

Q9NWH2
RVAGGASMSQISEAL

ZYG11A

336

Q6WRX3
RSTLQAIGSAAAAGM

ZFYVE26

906

Q68DK2
VGAGGNKSRLTLSMS

PURA

91

Q00577
SQDGSGFSRILSMLA

ZNF318

501

Q5VUA4
LSSILGRSNLKFAGM

SHC1

216

P29353
SSGFMVLLDTRTGLV

WDR81

1806

Q562E7
VSQRAGRSAVGTKMT

ZMYM3

296

Q14202
IKSLEAARGNGTSMI

ETF1

21

P62495
VLGGMAVSSGRSLVS

KLHL38

336

Q2WGJ6
MSIARSTVGVAALNG

KLHL1

586

Q9NR64
VLSKAGMSGARSRNI

KIAA1958

516

Q8N8K9
ALGSDGVRVTMESAL

MYO1C

26

O00159
MKRSSVSSGGAGRLS

NDC80

1

O14777