Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

EP400 HLTF

1.19e-043792GO:0140658
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

EP400 HLTF

1.40e-0312792GO:0008094
GeneOntologyMolecularFunctionATP-dependent activity

EP400 HLTF ATP8B2

2.12e-0361493GO:0140657
GeneOntologyMolecularFunctionhelicase activity

EP400 HLTF

2.16e-0315892GO:0004386
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

EP400 HLTF LCMT2

2.44e-0364593GO:0140640
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

FADS2B PTGS2

3.23e-0319492GO:0016705
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

EP400 HLTF

5.81e-0326292GO:0140097
GeneOntologyBiologicalProcessunsaturated fatty acid biosynthetic process

FADS2B PTGS2

2.57e-045692GO:0006636
DomainSNF2_N

EP400 HLTF

7.91e-053282PF00176
DomainSNF2_N

EP400 HLTF

7.91e-053282IPR000330
DomainHelicase_C

EP400 HLTF

8.90e-0410782PF00271
DomainHELICc

EP400 HLTF

8.90e-0410782SM00490
DomainHelicase_C

EP400 HLTF

9.07e-0410882IPR001650
DomainHELICASE_CTER

EP400 HLTF

9.24e-0410982PS51194
DomainHELICASE_ATP_BIND_1

EP400 HLTF

9.24e-0410982PS51192
DomainDEXDc

EP400 HLTF

9.24e-0410982SM00487
DomainHelicase_ATP-bd

EP400 HLTF

9.40e-0411082IPR014001
Domain-

EP400 HLTF

3.80e-02746823.40.50.300
Cytoband12q24.33

EP400 EP400P1

4.79e-054810212q24.33
CytobandEnsembl 112 genes in cytogenetic band chr12q24

EP400 EP400P1

3.50e-03415102chr12q24
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

DIAPH1 EP400 HLTF ATP8B2

4.86e-0562984Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K1
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Mesoderm|GW16 / Sample Type, Dataset, Time_group, and Cell type.

EP400P1 PTGS2

4.20e-04139102d441c29852c28928ecb696b4b95e31b30c17116b
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LCMT2 ATP8B2

4.82e-0414910265778f19599b4955c0a16f0121237656449431fb
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTH1R LCMT2

5.48e-04159102fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTH1R LCMT2

5.48e-041591028bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTH1R LCMT2

5.48e-04159102aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTH1R PTGS2

6.19e-041691026ff1172da690ca17f7108f1617b255b766971a57
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLTF PTGS2

6.33e-041711025885e69e997cc2f6a27afebfe57001ca0ac062a6
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLTF PTGS2

6.41e-041721023d83b2f03ad3af4dae3fe6cc0a0ef356872ca94f
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLTF PTGS2

6.41e-04172102a3d431aed12c1192e8dca1dc85b8340fb7354f8d
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLTF PTGS2

6.41e-04172102028a5441242b2cc760cafc1822120180619c63ae
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLTF PTGS2

6.41e-041721029fc70b1a143a8ec910336c23b761d908bb6aecb2
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLTF PTGS2

6.41e-0417210213d7117f92a92d77d6b4335ed800c585dc8b4511
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

LCMT2 PTGS2

7.56e-041871023c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCellcontrol-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

HLTF ATP8B2

7.89e-04191102afebdc59a1f884ce3f2f5fe040e16b0e95e4e7c5
ToppCelldistal-Hematologic-Basophil/Mast_2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HLTF PTGS2

8.05e-04193102dcdc1498726c68bf590bf84cb81e5f7fb7ba4d78
ToppCelldistal-3-Hematologic-Basophil/Mast_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HLTF PTGS2

8.05e-0419310223c6c798525dad43eff792727902ea562bf373be
ToppCelldistal-Hematologic-Basophil/Mast_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HLTF PTGS2

8.05e-04193102f22d0a2ea6bbdd625909ccb6a89aca89ab670306
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLTF PTGS2

8.14e-041941029d7f232ef5f27c28f325edfa6614f479013acbba
ToppCellhealthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

DIAPH1 ATP8B2

8.30e-04196102af00c31612e4fe068e5fccae05368edba46bbd20
ToppCellBiopsy_Other_PF-Immune-Mast_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

HLTF PTGS2

8.47e-041981029f015553598d4c6774b2f9759e8c0f0f93e51c67
ComputationalGenes in the cancer module 470.

PTH1R PTGS2

3.11e-051662MODULE_470
DrugRimexolone [49697-38-3]; Down 200; 10.8uM; MCF7; HT_HG-U133A

DIAPH1 LCMT2 ATP8B2

5.31e-05199935517_DN
Druggenistin

PTH1R PTGS2

3.12e-046892ctd:C040641
Drugoleoresins

DIAPH1 PTGS2

3.90e-047692ctd:C018620
Drugalpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide

HLTF PTGS2

4.00e-047792ctd:C095512
Drugtelmisartan

PTH1R PTGS2

6.34e-049792ctd:C084178
DiseaseKidney Neoplasm

HLTF PTGS2

8.01e-0540102C0022665
DiseaseMalignant neoplasm of kidney

HLTF PTGS2

1.02e-0445102C0740457
DiseaseLung diseases

PTH1R PTGS2

3.06e-0478102C0024115

Protein segments in the cluster

PeptideGeneStartEntry
FFLQHFQGNMMDFLA

EP400

391

Q96L91
VEEFFMDLHNFRNMF

DIAPH1

1131

O60610
FAILFAMHSNGLFDM

ATP8B2

1051

P98198
AMHSNGLFDMFPNQF

ATP8B2

1056

P98198
QLTHQFFHRMMGFFF

KIAA0100

2016

Q14667
SFQGCMAQLFMDHLF

OR4A15

121

Q8NGL6
DPQGSNMMFAFFAQH

PTGS2

176

P35354
NMMFAFFAQHFTHQF

PTGS2

181

P35354
LIELFFLQHFQGNMM

EP400P1

376

Q6ZTU2
FLQHFQGNMMDFLAF

EP400P1

381

Q6ZTU2
IAEAMNMFHANLGFF

FADS2B

156

A8MWK0
NMFHANLGFFFLHFV

FADS2B

161

A8MWK0
FGANNAFTMPLHMTF

HLTF

136

Q14527
MHYEMLFNSFQGFFV

PTH1R

441

Q03431
MRPQDAFGQFMLQHF

LCMT2

221

O60294