Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	bitter taste receptor activity	TAS2R14 TAS2R43 TAS2R46 TAS2R50	2.30e-05	27	125	4	GO:0033038
GeneOntologyMolecularFunction	taste receptor activity	TAS2R14 TAS2R43 TAS2R46 TAS2R50	5.20e-05	33	125	4	GO:0008527
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	ALDH8A1 AKR1B10 ALDH4A1 ALDH3A2	2.30e-04	48	125	4	GO:0016620
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the aldehyde or oxo group of donors	ALDH8A1 AKR1B10 ALDH4A1 ALDH3A2	4.18e-04	56	125	4	GO:0016903
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIK2 GABRA1 GABRA2	4.40e-04	24	125	3	GO:0099507
GeneOntologyCellularComponent	leading edge membrane	DPP4 PSD2 CFL1 PSD3 ADGRV1 HCN2 SYNJ2 MACF1 GABRA1 GABRA2	5.49e-07	210	125	10	GO:0031256
GeneOntologyCellularComponent	cell projection membrane	DPP4 PSD2 CFL1 PSD3 ADGRV1 HCN2 AQP1 SYNJ2 MACF1 TAS2R43 TAS2R46 GABRA1 GABRA2	1.92e-06	431	125	13	GO:0031253
GeneOntologyCellularComponent	cell leading edge	DPP4 PSD2 MYLK CFL1 PSD3 ADGRV1 HCN2 SYNJ2 SSX2IP MACF1 PLD1 GABRA1 GABRA2	9.60e-06	500	125	13	GO:0031252
GeneOntologyCellularComponent	ruffle membrane	PSD2 CFL1 PSD3 SYNJ2 MACF1	4.81e-04	108	125	5	GO:0032587
GeneOntologyCellularComponent	cleavage furrow	PSD2 MYLK PSD3 RACGAP1	4.89e-04	61	125	4	GO:0032154
Domain	TAS2R	TAS2R14 TAS2R43 TAS2R46 TAS2R50	2.32e-05	26	122	4	PF05296
Domain	T2R	TAS2R14 TAS2R43 TAS2R46 TAS2R50	2.32e-05	26	122	4	IPR007960
Domain	ADF/Cofilin	CFL1 CFL2	1.26e-04	3	122	2	IPR017904
Domain	Ald_DH_CS_GLU	ALDH8A1 ALDH4A1 ALDH3A2	1.43e-04	16	122	3	IPR029510
Domain	Ald_DH_CS_CYS	ALDH8A1 ALDH4A1 ALDH3A2	1.73e-04	17	122	3	IPR016160
Domain	ALDEHYDE_DEHYDR_CYS	ALDH8A1 ALDH4A1 ALDH3A2	2.07e-04	18	122	3	PS00070
Domain	ALDEHYDE_DEHYDR_GLU	ALDH8A1 ALDH4A1 ALDH3A2	2.07e-04	18	122	3	PS00687
Domain	-	ALDH8A1 ALDH4A1 ALDH3A2	2.44e-04	19	122	3	3.40.605.10
Domain	Aldedh	ALDH8A1 ALDH4A1 ALDH3A2	2.44e-04	19	122	3	PF00171
Domain	Ald_DH_C	ALDH8A1 ALDH4A1 ALDH3A2	2.44e-04	19	122	3	IPR016163
Domain	Ald_DH_N	ALDH8A1 ALDH4A1 ALDH3A2	2.44e-04	19	122	3	IPR016162
Domain	Ald_DH/histidinol_DH	ALDH8A1 ALDH4A1 ALDH3A2	2.44e-04	19	122	3	IPR016161
Domain	Aldehyde_DH_dom	ALDH8A1 ALDH4A1 ALDH3A2	2.44e-04	19	122	3	IPR015590
Domain	-	ALDH8A1 ALDH4A1 ALDH3A2	2.44e-04	19	122	3	3.40.309.10
Domain	GABAAa_rcpt	GABRA1 GABRA2	6.24e-04	6	122	2	IPR001390
Pathway	SIG_CHEMOTAXIS	MYLK CFL1 CFL2 PIK3CD RACGAP1	1.11e-05	45	93	5	M5193
Pathway	BIOCARTA_FLUMAZENIL_PATHWAY	PRKCE GABRA1 GABRA2	2.27e-05	9	93	3	M22034
Pathway	KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS	DOCK2 CFL1 CFL2 PIK3CD PRKCE PLD1	4.03e-05	96	93	6	M16121
Pathway	REACTOME_SENSORY_PERCEPTION_OF_TASTE	TAS2R14 TAS2R43 TAS2R46 TAS2R50	4.87e-05	31	93	4	MM15691
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	TAS2R14 TAS2R43 TAS2R46 TAS2R50	9.92e-05	37	93	4	MM15067
Pathway	PID_LPA4_PATHWAY	RPS6KA5 ADCY2 PRKCE	1.19e-04	15	93	3	M56
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	TAS2R14 TAS2R43 TAS2R46 TAS2R50	1.22e-04	39	93	4	M793
Pathway	REACTOME_SENSORY_PERCEPTION_OF_TASTE	TAS2R14 TAS2R43 TAS2R46 TAS2R50	2.55e-04	47	93	4	M42524
Pathway	KEGG_TASTE_TRANSDUCTION	TAS2R14 TAS2R43 TAS2R46 TAS2R50	3.77e-04	52	93	4	M5785
Pubmed	Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.	TAS2R14 TAS2R43 TAS2R46 TAS2R50	1.14e-07	13	126	4	15938754
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ACSL6 FRAS1 EP400 PSD3 ADCY2 ARHGEF9 MACF1 CHD6 ARRDC3 DOP1B PCNT	3.00e-07	407	126	11	12693553
Pubmed	A novel family of mammalian taste receptors.	TAS2R14 TAS2R43 TAS2R46 TAS2R50	9.37e-07	21	126	4	10761934
Pubmed	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.	TAS2R14 TAS2R43 TAS2R46 TAS2R50	1.14e-06	22	126	4	12734386
Pubmed	The molecular receptive ranges of human TAS2R bitter taste receptors.	TAS2R14 TAS2R43 TAS2R46 TAS2R50	1.38e-06	23	126	4	20022913
Pubmed	Receptors for bitter and sweet taste.	TAS2R14 TAS2R43 TAS2R46 TAS2R50	1.96e-06	25	126	4	12139982
Pubmed	Molecular mechanisms of bitter and sweet taste transduction.	TAS2R14 TAS2R43 TAS2R46 TAS2R50	2.31e-06	26	126	4	11696554
Pubmed	Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.	TAS2R14 TAS2R43 TAS2R46 TAS2R50	2.70e-06	27	126	4	12581520
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	BRPF3 EP400 ZC3H15 ASH1L L1TD1 RALGAPA2 MLKL THADA TADA1 ZFHX4 HPN SSX2IP MACF1 PLD1 TOP1 TOP2A	2.97e-06	1116	126	16	31753913
Pubmed	Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.	TAS2R14 TAS2R43 TAS2R46 TAS2R50	3.14e-06	28	126	4	15744053
Pubmed	Mapping of QTLs for oral alcohol self-administration in B6.C and B6.I quasi-congenic RQI strains.	TAS2R14 TAS2R43 TAS2R46 TAS2R50	4.18e-06	30	126	4	17273929
Pubmed	Adaptive diversification of bitter taste receptor genes in Mammalian evolution.	TAS2R14 TAS2R43 TAS2R46 TAS2R50	4.18e-06	30	126	4	12679530
Pubmed	Evolution of bitter taste receptors in humans and apes.	TAS2R14 TAS2R43 TAS2R46 TAS2R50	7.00e-06	34	126	4	15496549
Pubmed	The mouse gene encoding the GM2 activator protein (Gm2a): cDNA sequence, expression, and chromosome mapping.	ALDH3A2 GABRA1 GABRA2	7.50e-06	11	126	3	7713516
Pubmed	The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.	TAS2R43 TAS2R46 TAS2R50	9.97e-06	12	126	3	12379855
Pubmed	Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice.	HTR2A GABRA1 GABRA2	1.29e-05	13	126	3	22569571
Pubmed	Involvement of neurotransmitters in the action of growth hormone-releasing hormone antagonist on passive avoidance learning.	HTR2A GABRA1 GABRA2	1.29e-05	13	126	3	22640814
Pubmed	Identification and characterization of human taste receptor genes belonging to the TAS2R family.	TAS2R43 TAS2R46 TAS2R50	1.29e-05	13	126	3	12584440
Pubmed	Malignant progressive tumor cell clone exhibits significant up-regulation of cofilin-2 and 27-kDa modified form of cofilin-1 compared to regressive clone.	CFL1 CFL2	1.30e-05	2	126	2	24023293
Pubmed	Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family.	PARP14 STAT6	1.30e-05	2	126	2	21911376
Pubmed	Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture.	TAS2R43 TAS2R50	1.30e-05	2	126	2	33461297
Pubmed	Mapping of human non-muscle type cofilin (CFL1) to chromosome 11q13 and muscle-type cofilin (CFL2) to chromosome 14.	CFL1 CFL2	1.30e-05	2	126	2	8800436
Pubmed	Differential and common DNA repair pathways for topoisomerase I- and II-targeted drugs in a genetic DT40 repair cell screen panel.	TOP1 TOP2A	1.30e-05	2	126	2	24130054
Pubmed	α2-containing GABAA receptors expressed in hippocampal region CA3 control fast network oscillations.	GABRA1 GABRA2	1.30e-05	2	126	2	23109109
Pubmed	Cofilin hyperactivation in HIV infection and targeting the cofilin pathway using an anti-α4β7 integrin antibody.	CFL1 CFL2	1.30e-05	2	126	2	30662943
Pubmed	Attenuated PLD1 association and signalling at the H452Y polymorphic form of the 5-HT(2A) receptor.	HTR2A PLD1	1.30e-05	2	126	2	23314176
Pubmed	Loss of core fucosylation in both ST6GAL1 and its substrate enhances glycoprotein sialylation in mice.	ST6GAL1 FUT8	1.30e-05	2	126	2	32141499
Pubmed	GAB(A) receptors present higher affinity and modified subunit composition in spinal motor neurons from a genetic model of amyotrophic lateral sclerosis.	GABRA1 GABRA2	1.30e-05	2	126	2	18973555
Pubmed	Selective potentiation of Stat-dependent gene expression by collaborator of Stat6 (CoaSt6), a transcriptional cofactor.	PARP14 STAT6	1.30e-05	2	126	2	16537510
Pubmed	Inhibition of DNA topoisomerases I and II by G3 PAMAM-NH2 dendrimer-modified digoxin and proscillaridin A conjugates in a cell free system.	TOP1 TOP2A	1.30e-05	2	126	2	21229879
Pubmed	Characterization of a novel cofilin isoform that is predominantly expressed in mammalian skeletal muscle.	CFL1 CFL2	1.30e-05	2	126	2	8195165
Pubmed	STK295900, a dual inhibitor of topoisomerase 1 and 2, induces G(2) arrest in the absence of DNA damage.	TOP1 TOP2A	1.30e-05	2	126	2	23349762
Pubmed	t(5;12)(q23-31;p13) with ETV6-ACSL6 gene fusion in polycythemia vera.	ACSL6 ETV6	1.30e-05	2	126	2	16572202
Pubmed	Differential expression of up-regulated cofilin-1 and down-regulated cofilin-2 characteristic of pancreatic cancer tissues.	CFL1 CFL2	1.30e-05	2	126	2	21894436
Pubmed	Developmental seizures and mortality result from reducing GABAA receptor α2-subunit interaction with collybistin.	ARHGEF9 GABRA2	1.30e-05	2	126	2	30087324
Pubmed	Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers.	TOP1 TOP2A	1.30e-05	2	126	2	25777966
Pubmed	Consequences of prenatal exposure to diazepam on the respiratory parameters, respiratory network activity and gene expression of alpha1 and alpha2 subunits of GABA(A) receptor in newborn rat.	GABRA1 GABRA2	1.30e-05	2	126	2	18085262
Pubmed	Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling.	GABRA1 GABRA2	1.30e-05	2	126	2	21073549
Pubmed	Implications of Topoisomerase (TOP1 and TOP2α) Expression in Patients With Breast Cancer.	TOP1 TOP2A	1.30e-05	2	126	2	33144457
Pubmed	β-Elemene Inhibits Cell Proliferation by Regulating the Expression and Activity of Topoisomerases I and IIα in Human Hepatocarcinoma HepG-2 Cells.	TOP1 TOP2A	1.30e-05	2	126	2	26221582
Pubmed	Analysis of expression and function of topoisomerase I and II during meiosis in male mice.	TOP1 TOP2A	1.30e-05	2	126	2	9094096
Pubmed	DNA topoisomerase I and II expression in drug resistant germ cell tumours.	TOP1 TOP2A	1.30e-05	2	126	2	12237772
Pubmed	Testing the silence of mutations: Transcriptomic and behavioral studies of GABA(A) receptor α1 and α2 subunit knock-in mice.	GABRA1 GABRA2	1.30e-05	2	126	2	21056629
Pubmed	DNA topoisomerase 1 and 2A function as oncogenes in liver cancer and may be direct targets of nitidine chloride.	TOP1 TOP2A	1.30e-05	2	126	2	30132517
Pubmed	RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of α2 GABAA receptors.	ARHGEF9 GABRA2	1.30e-05	2	126	2	29069083
Pubmed	The ADF/cofilin proteins: stimulus-responsive modulators of actin dynamics.	CFL1 CFL2	1.30e-05	2	126	2	8589446
Pubmed	The ADF/cofilin family: actin-remodeling proteins.	CFL1 CFL2	1.30e-05	2	126	2	12049672
Pubmed	Phospholipase D1 modulates protein kinase C-epsilon in retinal pigment epithelium cells during inflammatory response.	PRKCE PLD1	1.30e-05	2	126	2	27793751
Pubmed	Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13).	ACSL6 ETV6	1.30e-05	2	126	2	10502316
Pubmed	DOCK2 and phosphoinositide-3 kinase δ mediate two complementary signaling pathways for CXCR5-dependent B cell migration.	DOCK2 PIK3CD	1.30e-05	2	126	2	36341455
Pubmed	Natural Products as Anti-Cancerous Therapeutic Molecules Targeted towards Topoisomerases.	TOP1 TOP2A	1.30e-05	2	126	2	32951576
Pubmed	Lack of topoisomerase copy number changes in patients with de novo and relapsed diffuse large B-cell lymphoma.	TOP1 TOP2A	1.30e-05	2	126	2	25931012
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ERAP1 PSD3 ADGRV1 MACF1 CHD6 DOP1B PCNT	1.90e-05	225	126	7	12168954
Pubmed	Clinicopathological Significance of the Proliferation Markers Ki67, RacGAP1, and Topoisomerase 2 Alpha in Breast Cancer.	RACGAP1 TOP2A	3.90e-05	3	126	2	27284123
Pubmed	Comparative evaluation of three proliferation markers, Ki-67, TOP2A, and RacGAP1, in bronchopulmonary neuroendocrine neoplasms: Issues and prospects.	RACGAP1 TOP2A	3.90e-05	3	126	2	27259241
Pubmed	Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells.	TOP1 TOP2A	3.90e-05	3	126	2	22375014
Pubmed	PARP-14, a member of the B aggressive lymphoma family, transduces survival signals in primary B cells.	PARP14 STAT6	3.90e-05	3	126	2	19147789
Pubmed	Dephosphorylation of serine 3 regulates nuclear translocation of cofilin.	CFL1 CFL2	3.90e-05	3	126	2	8824278
Pubmed	CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway.	DOCK2 PIK3CD	3.90e-05	3	126	2	19451552
Pubmed	B cell-intrinsic and -extrinsic regulation of antibody responses by PARP14, an intracellular (ADP-ribosyl)transferase.	PARP14 STAT6	3.90e-05	3	126	2	23956424
Pubmed	Cofilin-mediated Neuronal Apoptosis via p53 Translocation and PLD1 Regulation.	CFL1 PLD1	3.90e-05	3	126	2	28912445
Pubmed	Validity of the proliferation markers Ki67, TOP2A, and RacGAP1 in molecular subgroups of breast cancer.	RACGAP1 TOP2A	3.90e-05	3	126	2	23135572
Pubmed	PARP14 correlates with GBM proliferation and poor prognosis by elevating expression of SAMD/SAMD9L.	SAMD9 PARP14	3.90e-05	3	126	2	37612499
Pubmed	Complex role of collybistin and gephyrin in GABAA receptor clustering.	ARHGEF9 GABRA2	3.90e-05	3	126	2	20622020
Pubmed	The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics.	CFL1 CFL2	3.90e-05	3	126	2	11809832
Pubmed	Gene expression meta-analysis reveals the down-regulation of three GABA receptor subunits in the superior temporal gyrus of patients with schizophrenia.	GABRA1 GABRA2	3.90e-05	3	126	2	32376074
Pubmed	Specific GABAA circuits for visual cortical plasticity.	GABRA1 GABRA2	3.90e-05	3	126	2	15017002
Pubmed	DNA topoisomerases participate in fragility of the oncogene RET.	TOP1 TOP2A	3.90e-05	3	126	2	24040417
Pubmed	HIV-1 Nef interferes with host cell motility by deregulation of Cofilin.	CFL1 CFL2	3.90e-05	3	126	2	19683683
Pubmed	The association between the p53/topoisomerase I and p53/ topoisomerase IIalpha immunophenotypes and the progression of ovarian carcinomas.	TOP1 TOP2A	3.90e-05	3	126	2	23214297
Pubmed	Specific subtypes of GABAA receptors mediate phasic and tonic forms of inhibition in hippocampal pyramidal neurons.	GABRA1 GABRA2	3.90e-05	3	126	2	16835366
Pubmed	Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones.	GABRA1 GABRA2	3.90e-05	3	126	2	18063661
Pubmed	GABRG1 and GABRA2 as independent predictors for alcoholism in two populations.	GABRA1 GABRA2	3.90e-05	3	126	2	18818659
Pubmed	THADA, SDHAF4, and MACF1 Gene Polymorphisms and Placental Expression in Women with Gestational Diabetes.	THADA MACF1	3.90e-05	3	126	2	36672824
Pubmed	Analysis of the presence and abundance of GABAA receptors containing two different types of alpha subunits in murine brain using point-mutated alpha subunits.	GABRA1 GABRA2	3.90e-05	3	126	2	15304513
Pubmed	TIRF microscopy analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover.	CFL1 CFL2	3.90e-05	3	126	2	26996939
Pubmed	Biophysics of actin filament severing by cofilin.	CFL1 CFL2	3.90e-05	3	126	2	23395798
Pubmed	How to engage Cofilin.	CFL1 CFL2	3.90e-05	3	126	2	18808680
Pubmed	Variability in the benzodiazepine response of serotonin 5-HT1A receptor null mice displaying anxiety-like phenotype: evidence for genetic modifiers in the 5-HT-mediated regulation of GABA(A) receptors.	GABRA1 GABRA2	3.90e-05	3	126	2	15254090
Pubmed	The alpha 1, alpha 2, and alpha 3 subunits of GABAA receptors: comparison in seizure-prone and -resistant mice and during development.	GABRA1 GABRA2	3.90e-05	3	126	2	1356407
Pubmed	Candidate genes for alcohol dependence: A genetic association study from India.	GABRA1 GABRA2	3.90e-05	3	126	2	28361821
Pubmed	Genome-Protective Topoisomerase 2a-Dependent G2 Arrest Requires p53 in hTERT-Positive Cancer Cells.	PRKCE TOP2A	3.90e-05	3	126	2	35247890
Pubmed	ETV6::ACSL6 translocation-driven super-enhancer activation leads to eosinophilia in acute lymphoblastic leukemia through IL-3 overexpression.	ACSL6 ETV6	3.90e-05	3	126	2	38356460
Pubmed	Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activities.	TOP1 TOP2A	3.90e-05	3	126	2	9049244
Pubmed	Topoisomerase expression in oral squamous cell carcinoma: relationship with cancer stem cells profiles and lymph node metastasis.	TOP1 TOP2A	3.90e-05	3	126	2	22672768
Pubmed	Hypoxia-induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway.	CFL1 PLD1	3.90e-05	3	126	2	33784016
Pubmed	Modulation of topoisomerase activities by tumor necrosis factor.	TOP1 TOP2A	3.90e-05	3	126	2	7842491
Pubmed	CD26 expression on T-anaplastic large cell lymphoma (ALCL) line Karpas 299 is associated with increased expression of versican and MT1-MMP and enhanced adhesion.	DPP4 VCAN	3.90e-05	3	126	2	24180670
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MYLK CFL1 CFL2 ADAM7 ASH1L SPG11 TFRC PDIA4 MACF1 CHD6 DTHD1 DNAH8 TOP1 TOP2A MYBPC1 PCNT	6.83e-05	1442	126	16	35575683
Pubmed	Cofilin weakly interacts with 14-3-3 and therefore can only indirectly participate in regulation of cell motility by small heat shock protein HspB6 (Hsp20).	CFL1 CFL2	7.78e-05	4	126	2	22450169
Pubmed	Suprachiasmatic to paraventricular nuclei interaction generates normal food searching rhythms in mice.	GABRA1 GABRA2	7.78e-05	4	126	2	36277219
Pubmed	Expression of cofilin isoforms during development of mouse striated muscles.	CFL1 CFL2	7.78e-05	4	126	2	10813634
Pubmed	Direct stimulation of receptor-controlled phospholipase D1 by phospho-cofilin.	CFL1 PLD1	7.78e-05	4	126	2	17853892
Pubmed	The α1, α2, α3, and γ2 subunits of GABAA receptors show characteristic spatial and temporal expression patterns in rhombencephalic structures during normal human brain development.	GABRA1 GABRA2	7.78e-05	4	126	2	26518133
Pubmed	Gephyrin is critical for glycine receptor clustering but not for the formation of functional GABAergic synapses in hippocampal neurons.	GABRA1 GABRA2	7.78e-05	4	126	2	14715953
Pubmed	Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs.	FRAS1 AQP1	7.78e-05	4	126	2	15838507
Pubmed	Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype.	GABRA1 GABRA2	7.78e-05	4	126	2	25865415
Pubmed	Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin.	CFL1 CFL2	7.78e-05	4	126	2	12684437
Pubmed	Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse colon.	GABRA1 GABRA2	7.78e-05	4	126	2	25080596
Pubmed	ADF/Cofilin-Mediated Actin Turnover Promotes Axon Regeneration in the Adult CNS.	CFL1 CFL2	7.78e-05	4	126	2	31400829
GeneFamily	Taste 2 receptors	TAS2R14 TAS2R43 TAS2R46 TAS2R50	3.15e-05	39	84	4	1162
GeneFamily	Aldehyde dehydrogenases	ALDH8A1 ALDH4A1 ALDH3A2	8.88e-05	19	84	3	398
GeneFamily	Topoisomerases	TOP1 TOP2A	3.16e-04	6	84	2	1050
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	EP400 MSANTD1 CHD6	1.92e-03	53	84	3	532
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PSD2 PSD3 PLEKHD1 ARHGEF9 PLD1	2.73e-03	206	84	5	682
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRA1 GABRA2	3.46e-03	19	84	2	563
GeneFamily	Sialyltransferases	ST6GAL1 ST6GALNAC4	3.84e-03	20	84	2	438
GeneFamily	Protein disulfide isomerases	PDIA4 TMX1	4.23e-03	21	84	2	692
Coexpression	GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	CAMK1D SETD4 HID1 DZIP1 CXCR6 HECTD2 ARHGEF9 DNAH8	5.28e-06	199	125	8	M9159
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000	DPP4 FRAS1 RPS6KA5 PSD3 ST6GAL1 DZIP1 CYP39A1 ADCY2 ORC1 ZFHX4 SULF1 VCAN AKR1B10 KLHL23 PACC1 PLD1 TOP2A MYBPC1	9.84e-07	831	120	18	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_500	PSD3 APOC1 ADCY2 ZFHX4 SULF1 VCAN AKR1B10 KLHL23 PACC1 PLD1 TOP2A	5.89e-06	357	120	11	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_500
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#2_top-relative-expression-ranked_500	ORC1 ZFHX4 SULF1 AKR1B10 KLHL23 PACC1 PLD1	2.05e-05	147	120	7	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k2_500
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_100	AKR1B10 KLHL23 PACC1	2.05e-05	10	120	3	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k1_100
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500	PSD3 DZIP1 ORC1 ZFHX4 SULF1 VCAN AKR1B10 KLHL23 PACC1 PLD1 TOP2A	2.86e-05	423	120	11	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500
CoexpressionAtlas	dev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_500	BRPF3 ST6GAL1 ORC1 ZFHX4 SULF1 VCAN AKR1B10 KLHL23 PACC1 PLD1 ALDH3A2	3.46e-05	432	120	11	gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_500
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000	RPS6KA5 PSD3 APOC1 DZIP1 CYP39A1 ADCY2 ORC1 ZFHX4 SULF1 VCAN AKR1B10 KLHL23 PACC1 PLD1 TOP2A	3.59e-05	783	120	15	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#3	ACSL6 MPV17L PSD3 GRIK2 HID1 ADGRV1 RALGAPA2 CYP39A1 TFRC TADA1 SULF1 AKR1B10 PACC1 CHD6 PLD1 ALDH3A2	4.32e-05	893	120	16	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K3
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_1000	ETV6 ORC1 SULF1 KLHL23 PACC1 PLD1 ALDH3A2 MYBPC1	5.13e-05	231	120	8	gudmap_dev gonad_e11.5_M_GonMes_Sma_k4_1000
CoexpressionAtlas	dev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_200	ETV6 ORC1 SULF1 AKR1B10 KLHL23 PACC1 PLD1	5.38e-05	171	120	7	gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_200
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	DPP4 PSD3 ST6GAL1 DZIP1 ADCY2 ORC1 ZFHX4 SULF1 VCAN AKR1B10 KLHL23 ARHGEF9 PACC1 TOP2A MYBPC1	6.66e-05	827	120	15	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_500	PSD3 ADCY2 ZFHX4 SULF1 VCAN AKR1B10 KLHL23 PACC1 PLD1 TOP2A	7.21e-05	388	120	10	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_500
CoexpressionAtlas	dev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_1000	BRPF3 ETV6 ST6GAL1 RALGAPA2 ORC1 ZFHX4 SYNJ2 SULF1 VCAN AKR1B10 KLHL23 PACC1 PLD1 ALDH3A2 MYBPC1	7.62e-05	837	120	15	gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_1000
CoexpressionAtlas	dev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500	ETV6 APOC1 ORC1 ZFHX4 SULF1 AKR1B10 KLHL23 PACC1 PLD1 ALDH3A2	1.01e-04	404	120	10	gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_500
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_1000	CAMK1D MYLK RPS6KA5 CFL2 AQP1 ADCY2 TFRC ZFHX4 SULF1 HECTD2 VCAN ARHGEF9 OSBPL6 CSTF3	1.19e-04	772	120	14	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000
CoexpressionAtlas	dev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_100	ORC1 SULF1 AKR1B10 KLHL23 PLD1	1.28e-04	86	120	5	gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_100
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	ACSL6 PSD3 GRIK2 HID1 ADGRV1 RALGAPA2 CYP39A1 SULF1 PACC1	1.34e-04	339	120	9	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K3
CoexpressionAtlas	alpha beta T cells, preT.DN2.Th, Lin-/lo CD25hi CD44+ cKit+, Thymus, avg-3	DPP4 SESTD1 RPS6KA5 ETV6 TFRC MLKL TMEM97 TIMELESS FUT8 TOP2A	1.38e-04	420	120	10	GSM791136_500
CoexpressionAtlas	dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000	PSD3 APOC1 MND1 DZIP1 ADCY2 ORC1 ZFHX4 SULF1 VCAN AKR1B10 KLHL23 PACC1 ECI2 PLD1	1.65e-04	797	120	14	gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000
CoexpressionAtlas	alpha beta T cells, T.8SP69+.Th, 4- 8+ TCRhi 69+, Thymus, avg-3	HID1 DZIP1 TFRC CXCR6 PIK3CD HECTD2 TIMELESS DNAH8 TOP2A	2.19e-04	362	120	9	GSM399385_500
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#1_top-relative-expression-ranked_500	ZFHX4 SULF1 KLHL23 PACC1 PLD1	2.48e-04	99	120	5	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k1_500
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000	DOCK2 PSD3 APOC1 DZIP1 ADCY2 ZFHX4 SULF1 VCAN AKR1B10 KLHL23 PACC1 PLD1 TOP2A	2.86e-04	740	120	13	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_500	DPP4 ASH1L SULF1 RNF145 TOP1 MYBPC1	3.10e-04	161	120	6	gudmap_developingGonad_e12.5_ovary_k3_500
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000	PSD3 ETV6 ST6GAL1 ADCY2 ORC1 SULF1 VCAN AKR1B10 KLHL23 PACC1 PLD1 ALDH3A2 GABRA1 MYBPC1	3.15e-04	849	120	14	gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_200	ORC1 SULF1 AKR1B10 KLHL23 PACC1 PLD1	3.54e-04	165	120	6	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_200
CoexpressionAtlas	dev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_1000	BRPF3 ERAP1 ST6GAL1 APOC1 RALGAPA2 MLKL SYNJ2 HECTD2 VCAN AKR1B10 KLHL23 PRKCE PACC1 RNF145	4.52e-04	880	120	14	gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_1000
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 GRIK2 ADGRV1 ADCY2 ZFHX4 SULF1 DTHD1	3.73e-07	160	126	7	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 GRIK2 ADGRV1 ADCY2 ZFHX4 SULF1 DTHD1	3.73e-07	160	126	7	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MPV17L ALDH8A1 C16orf46 PDIA4 ST6GALNAC4 ALDH4A1 TOP2A	6.83e-07	175	126	7	89bf89466191da14896ed8928027f5b911436c22
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	DOCK2 PSD3 ETV6 CYP39A1 ZFHX4 FUT8 GABRA2	7.95e-07	179	126	7	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	facs-Large_Intestine-Distal\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 HPN IRAG2 ST6GALNAC4 TMEM97 FUT8	1.18e-06	190	126	7	3964a8390522b61b73235151bb0a2ff36b856867
ToppCell	droplet-Spleen-SPLEEN-1m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSL6 MND1 AQP1 HPN SSX2IP KLHL23 TMEM97	1.27e-06	192	126	7	a94f47a664a3c9d1b0250269674453309ab4bf95
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 HPN IRAG2 ST6GALNAC4 TMEM97 FUT8	1.32e-06	193	126	7	5a92697430f16c49e19a5f727d289d7bd1ece31c
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-secretory_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 HPN IRAG2 ST6GALNAC4 TMEM97 FUT8	1.32e-06	193	126	7	64bcdbb422f8da6fc3275e82f6aaf562f546a180
ToppCell	CF-Lymphoid-B_cell\|Lymphoid / Disease state, Lineage and Cell class	SESTD1 CAMK1D ST6GAL1 PARP14 IRAG2 FUT8 DNAH8	1.32e-06	193	126	7	7ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MYLK PSD3 FAM162B ZFHX4 HECTD2 VCAN MACF1	1.41e-06	195	126	7	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PSD2 ADGRV1 ADCY2 ZFHX4 MACF1 GABRA2 MYBPC1	1.67e-06	200	126	7	07d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCell	COVID-19_Severe-dn_T\|COVID-19_Severe / Disease condition and Cell class	SESTD1 CXCR6 MROH2B IRAG2 ECI2 DTHD1	3.21e-06	142	126	6	2008033881b9e1b20926c3508d6ebdb6f1a1528f
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPS6KA5 MLKL VCAN RACGAP1 ARHGEF37 TOP2A	9.32e-06	171	126	6	6e7ade1d14a3ec4c566476aac3eb509bd2661e39
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 CAMK1D MND1 PIK3CD RACGAP1 TOP2A	1.03e-05	174	126	6	7b318796728001c17b4043d2b033330c7be40c78
ToppCell	COVID-19-B_cells-Activated_B_cells\|COVID-19 / group, cell type (main and fine annotations)	DOCK2 CAMK1D ST6GAL1 IRAG2 FUT8 DNAH8	1.13e-05	177	126	6	653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCell	3'_v3-lymph-node_spleen-Mast-Mast_cell_lympho\|lymph-node_spleen / Manually curated celltypes from each tissue	TTC21A MND1 ADGRV1 PLD1 ALDH3A2 DNAH8	1.13e-05	177	126	6	53040dbeb18574a48e352e4bce252c7c3018762c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DPP4 PSD3 MND1 TIMELESS CHD6 TOP2A	1.37e-05	183	126	6	ba7753e9fe2a6a87c5264f299ac97da2ddbda178
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 HPN IRAG2 TMEM97 FUT8	1.37e-05	183	126	6	ee9c88be88221b7ad4ea9f890b17d6156fb3432e
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-Goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 HPN IRAG2 TMEM97 FUT8	1.37e-05	183	126	6	c52b84034503d931f7b87312d2ff86daff14152d
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HTR2A PLEKHD1 CYP39A1 SLC35F4 TADA1 PLD1	1.41e-05	184	126	6	658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 HPN IRAG2 ST6GALNAC4 TMEM97	1.46e-05	185	126	6	e29079ef09aee62c3e9756341db4e59ca9dbf7ac
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 HPN IRAG2 ST6GALNAC4 FUT8	1.46e-05	185	126	6	fd1911b57927c03470f9387962ca9581e5643fb3
ToppCell	facs-Large_Intestine-Distal-3m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 HPN IRAG2 ST6GALNAC4 FUT8	1.46e-05	185	126	6	7a18d525de6f874924bfc61b9666b307da86421a
ToppCell	facs-Large_Intestine-Distal-24m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 HPN IRAG2 ST6GALNAC4 TMEM97	1.46e-05	185	126	6	2ecc4b76b3645b65c226c2298bff307cc6479172
ToppCell	droplet-Large_Intestine-COLON:P+D-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAMK1D ST6GAL1 HID1 AQP1 TMEM97 FUT8	1.55e-05	187	126	6	a63fa3255ad58f3a73c596df99ce9649fdbaeb39
ToppCell	droplet-Large_Intestine-COLON:P+D\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAMK1D ST6GAL1 HID1 AQP1 TMEM97 FUT8	1.55e-05	187	126	6	b1bb5c48258a9d058614d23001899dbe44857a1f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPP4 FRAS1 ABCA13 DZIP1 ADGRV1 HPN	1.55e-05	187	126	6	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AQP1 TFRC ORC1 HPN SSX2IP TOP2A	1.55e-05	187	126	6	dceca7ae3dae96078cccc17a0d8a61b06fa6dffb
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAMK1D ST6GAL1 HID1 AQP1 TMEM97 FUT8	1.60e-05	188	126	6	bfd3b4f57785596b2bd2c657e0d2d8b0f40ba36d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPP4 FRAS1 DZIP1 ADGRV1 PLEKHD1 HPN	1.70e-05	190	126	6	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPP4 FRAS1 DZIP1 ADGRV1 PLEKHD1 HPN	1.70e-05	190	126	6	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	PARP14 ZNF169 TFRC MACF1 FUT8 DOP1B	1.75e-05	191	126	6	9454f642c3621370fa23640b631301346b300950
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MND1 ORC1 RACGAP1 TMEM97 TIMELESS TOP2A	1.75e-05	191	126	6	50854384fdaa0efa2e3227659d544ed09ac102f2
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DOCK2 C12orf56 TTC21A ST6GAL1 APOC1 IRAG2	1.80e-05	192	126	6	935a4a36881a9fa4daa02cba96af07f6686ed8d6
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 PDIA4 HPN ST6GALNAC4 FUT8	1.85e-05	193	126	6	4aee372ba2c0351b0221d0d468707d1ad21526d6
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-secretory_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 PDIA4 HPN ST6GALNAC4 FUT8	1.85e-05	193	126	6	aaa5042388dc451bff384c6bb237348f08280a08
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Pro-B\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MND1 ORC1 RACGAP1 TIMELESS TAS2R43 TOP2A	1.91e-05	194	126	6	3590ff471f74a361ee5bf02a58e3104cd3bf7d00
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PSD3 FAM162B ZFHX4 HECTD2 VCAN MACF1	1.91e-05	194	126	6	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK2 CAMK1D ETV6 PIK3CD VCAN IRAG2	2.02e-05	196	126	6	cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK2 ST6GAL1 HID1 IRAG2 FUT8 DNAH8	2.02e-05	196	126	6	fd18a9ae8401121ae276adff1a85d5f938e2df91
ToppCell	Parenchymal-10x5prime-Stromal-Mesofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 ALDH8A1 GRIK2 ZFHX4 SULF1 GABRA1	2.08e-05	197	126	6	88a86286b9c3ea3b076d7464faec42d0392ee7f8
ToppCell	Parenchymal-10x5prime-Stromal-Mesofibroblastic-Mesothelia\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 ALDH8A1 GRIK2 ZFHX4 SULF1 GABRA1	2.08e-05	197	126	6	2773d2eb5f232a7e49da116efffcb6bf5eb90810
ToppCell	Bronchial-10x5prime-Stromal-Mesofibroblastic-Mesothelia\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DPP4 FRAS1 ALDH8A1 GRIK2 SULF1 GABRA1	2.08e-05	197	126	6	26888af95a7cc082a1f1218af35b1f07cb9436ed
ToppCell	Bronchial-10x5prime-Stromal-Mesofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DPP4 FRAS1 ALDH8A1 GRIK2 SULF1 GABRA1	2.08e-05	197	126	6	438de7f0d35d81d5f5e41dcef7b2c54b6da03df4
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	MND1 ORC1 RACGAP1 PACC1 TIMELESS TOP2A	2.14e-05	198	126	6	880f9817f5145f10f29fc05c5866090433532fe2
ToppCell	Immune-monocyte\|World / Lineage, Cell type, age group and donor	DOCK2 CAMK1D ETV6 PIK3CD VCAN IRAG2	2.14e-05	198	126	6	d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCell	18-Airway-Mesenchymal-Mesenchyme_RSPO2+\|Airway / Age, Tissue, Lineage and Cell class	MYLK MND1 VCAN RACGAP1 MACF1 TOP2A	2.20e-05	199	126	6	7ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	MYLK PSD3 APOC1 DZIP1 VCAN MACF1	2.20e-05	199	126	6	c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast\|Megakaryocytic-erythropoietic / Lineage, cell class and subclass	APOC1 MND1 AQP1 ORC1 ECI2 TOP2A	2.20e-05	199	126	6	fa698f00d2dad74d28b4696c8c23dce70f123e52
ToppCell	Neuronal-Excitatory-eB(RORB)-FOLH1B--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HTR2A ST6GAL1 FAM162B IRAG2 PLD1 MYBPC1	2.26e-05	200	126	6	bdda59ffa0496256dd7a5937e88baac5c2a656c3
ToppCell	Neuronal-Excitatory-eB(RORB)-FOLH1B\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HTR2A ST6GAL1 FAM162B IRAG2 PLD1 MYBPC1	2.26e-05	200	126	6	dff0be30309b6f5f8757b0378ef05ce97f75dbe8
ToppCell	Neuronal-Excitatory-eB(RORB)-FOLH1B---L4-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HTR2A ST6GAL1 FAM162B IRAG2 PLD1 MYBPC1	2.26e-05	200	126	6	c3474e8a03ec4869fd3636a5559d36dd9c5fd414
ToppCell	Macroglial-Astrocytes-SLC14A1---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACSL6 PSD2 ADGRV1 ADCY2 OSBPL6 GABRA2	2.26e-05	200	126	6	d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCell	Macroglial-Astrocytes-SLC14A1----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACSL6 PSD2 ADGRV1 ADCY2 OSBPL6 GABRA2	2.26e-05	200	126	6	f861509b54185d89931db64da1b9d81986cc7938
ToppCell	healthy_donor-Lymphocytic-Proliferative_Lymphocyte\|healthy_donor / Disease condition, Lineage, Cell class and subclass	MND1 ORC1 RACGAP1 TMEM97 TIMELESS TOP2A	2.26e-05	200	126	6	e4eb915c29909cf8535a3603c68976545c05e54b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PSD2 ADGRV1 ADCY2 ZFHX4 MACF1 GABRA2	2.26e-05	200	126	6	d0812817ef99608994193787a62d39adeb2070ca
ToppCell	Macroglial-Astrocytes-SLC14A1\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACSL6 PSD2 ADGRV1 ADCY2 OSBPL6 GABRA2	2.26e-05	200	126	6	16f468217427921fa18c6d078ffa990eb019b257
ToppCell	healthy_donor-Lymphocytic-Proliferative_Lymphocyte-\|healthy_donor / Disease condition, Lineage, Cell class and subclass	MND1 ORC1 RACGAP1 TMEM97 TIMELESS TOP2A	2.26e-05	200	126	6	415e7556b5ac45688e2c6c30a52bd40e0eb27c7d
ToppCell	Macroglial-Astrocytes-SLC14A1--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACSL6 PSD2 ADGRV1 ADCY2 OSBPL6 GABRA2	2.26e-05	200	126	6	0442894c39eec69850c090957a5dc7bcecd21e04
ToppCell	Neuronal-Excitatory-eB(RORB)-FOLH1B-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HTR2A ST6GAL1 FAM162B IRAG2 PLD1 MYBPC1	2.26e-05	200	126	6	5c0c09e7b84fed053b299848bdff63ab842a445c
ToppCell	Macroglial-Astrocytes-SLC14A1-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACSL6 PSD2 ADGRV1 ADCY2 OSBPL6 GABRA2	2.26e-05	200	126	6	01819446deeab9054f5cfe889d53bb49d137dbc0
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PSD2 ADGRV1 ADCY2 ZFHX4 MACF1 GABRA2	2.26e-05	200	126	6	cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MND1 ORC1 RACGAP1 TIMELESS TOP2A PCNT	2.26e-05	200	126	6	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Grin2c_(SNc)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ALDH8A1 L1TD1 AQP1 ARMH2	3.48e-05	65	126	4	acc541e5a0e4be5ddd5702f191185c5b405b8762
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Grin2c_(SNc)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ALDH8A1 L1TD1 AQP1 ARMH2	3.48e-05	65	126	4	b8ab40d75b4078123cdffec2f5326cff65f67578
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GRIK2 SLC35F4 ORC1 GABRA2 MYBPC1	5.24e-05	142	126	5	819e983688d126d89a71abc03d72525cc759a347
ToppCell	LPS-antiTNF-Myeloid-Myeloid_granulocytic\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK2 CAMK1D ADCY2 VCAN TIMELESS	5.42e-05	143	126	5	4a0f26eef935fe68a1da5d319503059a8a8682dd
ToppCell	LPS-antiTNF-Myeloid-Myeloid_granulocytic-Neutrophils\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK2 CAMK1D ADCY2 VCAN TIMELESS	5.42e-05	143	126	5	65328a0a2f3972fac596e07933e74b2ef7cceb84
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MND1 FBXO10 CXCR6 DTHD1 FUT8	7.94e-05	155	126	5	7aba8ef53c9170ad8ed955c904c8991097ab1e32
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_low-phase\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	L1TD1 GRIK2 CSTF3 RACGAP1 TOP2A	8.69e-05	158	126	5	d72d6527dc50207ddbada262460d3c4bac249a19
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MYLK MPV17L HECTD2 OSBPL6 ARHGEF37	8.96e-05	159	126	5	7cda111bb98f1241989e49d490bdf51a712ea589
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FRAS1 ABCA13 C10orf67 ADAM7 ADGRV1	9.78e-05	162	126	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ORC1 MLKL SULF1 TTLL11 VCAN	1.10e-04	166	126	5	49103b75c3e08656c5774f56fd00d7bd53eefcfb
ToppCell	Ciliated_cells-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	TTC21A SLC9C2 C16orf46 OSBPL6 DTHD1	1.10e-04	166	126	5	4b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell	BAL-Severe-cDC_12\|Severe / Compartment, Disease Groups and Clusters	ACSL6 L1TD1 ORC1 TIMELESS TOP2A	1.13e-04	167	126	5	6c5aa9077ae7eb8887269d405972bd5b31596b19
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	APOC1 MLKL PIK3CD RACGAP1 TOP2A	1.16e-04	168	126	5	52fd65024af8683db11d931f7563cbe8eb815d1c
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-plasma_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 PDIA4 FUT8 MYBPC1	1.16e-04	168	126	5	bc7d5f0e5d222922eaf1c8e8c87aab189209d6b6
ToppCell	Control-Epithelial_cells-Airway_basal\|Control / group, cell type (main and fine annotations)	FRAS1 ABCA13 GRIK2 ADCY2 SULF1	1.26e-04	171	126	5	3965ced4be6db14265a90673502fceee425837ca
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MND1 ORC1 SULF1 VCAN TOP2A	1.26e-04	171	126	5	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	COVID-19-kidney-Bcells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK2 CAMK1D ST6GAL1 PIK3CD IRAG2	1.26e-04	171	126	5	8e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MND1 ORC1 SULF1 VCAN TOP2A	1.26e-04	171	126	5	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	metastatic_Brain-Fibroblasts-Undetermined\|Fibroblasts / Location, Cell class and cell subclass	SPG11 CYP39A1 ZFHX4 HECTD2 HPN	1.30e-04	172	126	5	c3822ff7329c3ac38c68c5c38cd67c390682e2a6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HTR2A ST6GAL1 FAM162B IRAG2 MYBPC1	1.30e-04	172	126	5	92e76cbf4807704790f42cf2507e92f85cd3bc92
ToppCell	droplet-Marrow-BM_(NON-STC)\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AQP1 TFRC VCAN TOP1 TOP2A	1.30e-04	172	126	5	6004327045f03d832fdabe6cb2f8b1b1db57789a
ToppCell	droplet-Marrow-BM_(NON-STC)-30m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AQP1 TFRC VCAN TOP1 TOP2A	1.30e-04	172	126	5	31c5710fd7ebb221e703545595f5ec0ee3a32bcf
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPP4 MYLK DZIP1 ADGRV1 PLEKHD1	1.37e-04	174	126	5	46bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 FAM162B PDIA4 FUT8	1.37e-04	174	126	5	cdfc50e5383c8670ce5109736aff36406f46c03d
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PSD2 FAM162B MSANTD1 RACGAP1 TOP2A	1.40e-04	175	126	5	a154b28b0b2180652d51d4c7d804b3b81b35899e
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	APOC1 PLEKHD1 MSANTD1 PACC1 TAS2R43	1.40e-04	175	126	5	c58a1f02d1e559d3638fe1500e960e82a8a7187b
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 GRIK2 ADGRV1 ZFHX4 DTHD1	1.40e-04	175	126	5	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPP4 CAMK1D L1TD1 THADA TIMELESS	1.44e-04	176	126	5	7b5e50eb144bf43ca0cf354a466eb58b976a79f1
ToppCell	Control-B_cells-B_cells\|Control / group, cell type (main and fine annotations)	DOCK2 ST6GAL1 PIK3CD IRAG2 DNAH8	1.44e-04	176	126	5	d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCell	facs-Kidney-nan-18m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPV17L ALDH8A1 AQP1 HPN ALDH4A1	1.48e-04	177	126	5	7f58286fc8797e9bdcf8ece0849f55680905955d
ToppCell	droplet-Skin-nan-18m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 CXCR6 PIK3CD IRAG2	1.52e-04	178	126	5	12d5c6be6cfbf733e3cb02780606b3725eda7d2b
ToppCell	Children_(3_yrs)-Epithelial-basal_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 PSD3 GRIK2 SULF1 ALDH3A2	1.52e-04	178	126	5	fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCell	Dividing_Macrophages-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	MND1 ORC1 RACGAP1 TIMELESS TOP2A	1.52e-04	178	126	5	1893fadac2ec3d5de0a641e57b7b2f962012a9ba
ToppCell	droplet-Skin-nan-18m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 CXCR6 PIK3CD IRAG2	1.52e-04	178	126	5	e0769ad06f92423a3cb6c78a61da3ba5bd9b4eae
ToppCell	droplet-Skin-nan-18m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GAL1 HID1 CXCR6 PIK3CD IRAG2	1.52e-04	178	126	5	11c2ce093b7538518c8d4497dc5b0b4da22bf1a8
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	SAMD9 TTC21A ETV6 PARP14 TOP1	1.56e-04	179	126	5	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	10x5'-blood-Lymphocytic_NK-Cycling_NK\|blood / Manually curated celltypes from each tissue	MND1 ORC1 RACGAP1 TIMELESS TOP2A	1.56e-04	179	126	5	c93711273055a999335ba8d0f6500e4549f46cec
Drug	girisopam	HTR2A CFL1 GABRA1 GABRA2	1.13e-06	15	125	4	CID000071257
Drug	Anthracenes	TOP1 TOP2A GABRA1	3.19e-06	6	125	3	ctd:D000873
Drug	nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A	ERAP1 SYNJ2 HPN VCAN SSX2IP TMEM97 ALDH4A1 GABRA2	1.40e-05	198	125	8	6983_UP
Drug	Secobarbital	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB00418
Drug	Metharbital	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB00463
Drug	Pentobarbital	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB00312
Drug	Talbutal	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB00306
Drug	Butalbital	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB00241
Drug	Butabarbital	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB00237
Drug	Barbituric acid derivative	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB01496
Drug	Barbital	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB01483
Drug	Hexobarbital	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB01355
Drug	Aprobarbital	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB01352
Drug	Amobarbital	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB01351
Drug	Heptabarbital	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB01354
Drug	Butethal	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB01353
Drug	Methylphenobarbital	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB00849
Drug	Primidone	GRIK2 GABRA1 GABRA2	1.88e-05	10	125	3	DB00794
Drug	Thiopental	GRIK2 GABRA1 GABRA2	2.58e-05	11	125	3	DB00599
Drug	Phenobarbital	GRIK2 GABRA1 GABRA2	2.58e-05	11	125	3	DB01174
Drug	batracylin	TOP1 TOP2A	2.99e-05	2	125	2	ctd:C057924
Drug	boswellic acid	TOP1 TOP2A	2.99e-05	2	125	2	ctd:C054625
Drug	ET-18-OCH3	MYLK ST6GAL1 TFRC PRKCE PLD1 ALDH3A2	5.32e-05	120	125	6	CID000001392
Disease	survival time, Sepsis	SAMD9 SLC35F4 TFRC	1.40e-05	12	120	3	EFO_0000714, HP_0100806
Disease	cholesteryl ester 24:1 measurement	APOC1 AXDND1	4.91e-05	3	120	2	EFO_0021446
Disease	Alcohol dependence	HTR2A GABRA2	1.63e-04	5	120	2	cv:C0001973
Disease	ALCOHOL DEPENDENCE	HTR2A GABRA2	1.63e-04	5	120	2	103780
Disease	Malignant Glioma	MYLK PSD3 TFRC TOP2A	1.94e-04	70	120	4	C0555198
Disease	mixed gliomas	MYLK PSD3 TFRC TOP2A	1.94e-04	70	120	4	C0259783
Disease	Malignant neoplasm of liver	ASH1L GRIK2 PRKCE TOP1 TOP2A	2.94e-04	142	120	5	C0345904
Disease	Liver neoplasms	ASH1L GRIK2 PRKCE TOP1 TOP2A	2.94e-04	142	120	5	C0023903
Disease	Manic	HTR2A GRIK2 ADCY2 DNAH8	2.94e-04	78	120	4	C0338831
Disease	Malignant neoplasm of breast	CFL1 CFL2 GRIK2 PLEKHD1 TFRC SYNJ2 MACF1 PACC1 TIMELESS ARRDC3 CYB5R4 TOP1 TOP2A	4.39e-04	1074	120	13	C0006142
Disease	Glioma	MYLK PSD3 TFRC TOP2A	4.46e-04	87	120	4	C0017638
Disease	response to statin, low density lipoprotein cholesterol measurement	APOC1 DZIP1	4.52e-04	8	120	2	EFO_0004611, GO_0036273
Disease	Bipolar Disorder	HTR2A ABCA13 GRIK2 ADCY2 TIMELESS DNAH8 GABRA1 PCNT	7.62e-04	477	120	8	C0005586
Disease	Malignant neoplasm of salivary gland	AQP1 VCAN TOP2A	8.22e-04	45	120	3	C0220636
Disease	Salivary Gland Neoplasms	AQP1 VCAN TOP2A	9.33e-04	47	120	3	C0036095
Disease	frontal fibrosing alopecia	CAMK1D ERAP1 TTLL11	9.93e-04	48	120	3	EFO_0009855
Disease	Condition, Preneoplastic	PSD2 CFL1 SULF1 ALDH4A1	1.08e-03	110	120	4	C0282313
Disease	Precancerous Conditions	PSD2 CFL1 SULF1 ALDH4A1	1.08e-03	110	120	4	C0032927
Disease	alcohol use disorder (implicated_via_orthology)	PSD2 CFL1 PSD3 PIK3CD PRKCE	1.23e-03	195	120	5	DOID:1574 (implicated_via_orthology)
Disease	Alzheimer disease, cognitive decline measurement, Cognitive impairment	ST6GAL1 TOP1	1.24e-03	13	120	2	EFO_0007710, HP_0100543, MONDO_0004975
Disease	sterol measurement	APOC1 CYP39A1	1.24e-03	13	120	2	EFO_0010231
Disease	leukemia (is_implicated_in)	ACSL6 ETV6	1.24e-03	13	120	2	DOID:1240 (is_implicated_in)
Disease	Drug habituation	ETV6 GRIK2 PRKCE DNAH8	1.27e-03	115	120	4	C0013170
Disease	Drug abuse	ETV6 GRIK2 PRKCE DNAH8	1.27e-03	115	120	4	C0013146
Disease	Prescription Drug Abuse	ETV6 GRIK2 PRKCE DNAH8	1.27e-03	115	120	4	C4316881
Disease	Substance-Related Disorders	ETV6 GRIK2 PRKCE DNAH8	1.27e-03	115	120	4	C0236969
Disease	Drug Use Disorders	ETV6 GRIK2 PRKCE DNAH8	1.27e-03	115	120	4	C0013222
Disease	Drug Dependence	ETV6 GRIK2 PRKCE DNAH8	1.27e-03	115	120	4	C1510472
Disease	Substance Dependence	ETV6 GRIK2 PRKCE DNAH8	1.27e-03	115	120	4	C0038580
Disease	Substance Use Disorders	ETV6 GRIK2 PRKCE DNAH8	1.27e-03	115	120	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	ETV6 GRIK2 PRKCE DNAH8	1.27e-03	115	120	4	C0029231
Disease	Substance abuse problem	ETV6 GRIK2 PRKCE DNAH8	1.31e-03	116	120	4	C0740858
Disease	neuroblastoma	DOCK2 HTR2A L1TD1 RSRC1	1.31e-03	116	120	4	EFO_0000621
Disease	Cocaine-Related Disorders	HTR2A RPS6KA5 DNAH8 GABRA2	1.35e-03	117	120	4	C0236736
Disease	Down syndrome (implicated_via_orthology)	SYNJ2 DOP1B	1.66e-03	15	120	2	DOID:14250 (implicated_via_orthology)
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	PSD3 SPG11 APOC1 MACF1	1.83e-03	127	120	4	EFO_0008595, EFO_0020947
Disease	Cocaine Abuse	HTR2A RPS6KA5 DNAH8 GABRA2	1.83e-03	127	120	4	C0009171
Disease	alcohol use disorder (is_implicated_in)	HTR2A GABRA2	1.90e-03	16	120	2	DOID:1574 (is_implicated_in)
Disease	response to cyclophosphamide	CAMK1D TMX1	2.14e-03	17	120	2	GO_1902518
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	PSD3 SPG11 APOC1 MACF1 TOP1	2.31e-03	225	120	5	EFO_0008317, EFO_0020947
Disease	susceptibility to vaginal yeast infection measurement	TEX2 SULF1 HECTD2	2.38e-03	65	120	3	EFO_0008412
Disease	Intellectual Disability	ASH1L MACF1 ALDH4A1 ALDH3A2 FUT8 TRAPPC6A GABRA2	2.40e-03	447	120	7	C3714756
Disease	Cocaine Dependence	HTR2A RPS6KA5 DNAH8 GABRA2	2.54e-03	139	120	4	C0600427
Disease	Alcohol abuse	HTR2A GABRA1 GABRA2	2.60e-03	67	120	3	C0085762
Disease	Chronic myeloproliferative disorder	ORC1 PCNT	2.68e-03	19	120	2	C1292778
Disease	monocyte count	DPP4 ASH1L APOC1 MND1 ADGRV1 THADA PIK3CD VCAN PRKCE PACC1 ST6GALNAC4 DTHD1 MYBPC1	2.81e-03	1320	120	13	EFO_0005091
Disease	congenital heart disease (implicated_via_orthology)	ADCY2 CHD6 MYBPC1	2.83e-03	69	120	3	DOID:1682 (implicated_via_orthology)
Disease	susceptibility to mononucleosis measurement	ADCY2 DNAH8 GABRA2	2.83e-03	69	120	3	EFO_0008403
Disease	serum albumin measurement	PSD3 GRIK2 APOC1 ADGRV1 MSANTD1 HPN MACF1 PCNT	2.95e-03	592	120	8	EFO_0004535
Disease	iron biomarker measurement, transferrin measurement	PSD3 TFRC	2.97e-03	20	120	2	EFO_0004461, EFO_0006341
Disease	Fetal Growth Retardation	SAMD9 ORC1	2.97e-03	20	120	2	C0015934
Disease	Manic Disorder	HTR2A GRIK2 ADCY2	3.07e-03	71	120	3	C0024713
Disease	systemising measurement	PIK3CD FUT8	3.27e-03	21	120	2	EFO_0010221
Disease	nucleotide measurement	DOCK2 SULF1 PRKCE	3.32e-03	73	120	3	EFO_0010513
Disease	colorectal cancer	ERAP1 L1TD1 ETV6 GRIK2 SYNJ2 VCAN MACF1 PCNT	3.34e-03	604	120	8	MONDO_0005575
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	PSD3 SPG11 APOC1 MACF1	3.34e-03	150	120	4	EFO_0004611, EFO_0020947
Disease	psoriasis, type 2 diabetes mellitus	TMC1 ERAP1 THADA	3.58e-03	75	120	3	EFO_0000676, MONDO_0005148
Disease	Seckel syndrome	ORC1 PCNT	3.59e-03	22	120	2	C0265202
Disease	N-glycan measurement	ST6GAL1 FUT8	3.59e-03	22	120	2	EFO_0004999

Protein segments in the cluster

Peptide	Gene	Start	Entry
QLKDEFFKLLQISLW	ARMT1	176	Q9H993
LKAHNFDERVFKIWK	FAM227B	176	Q96M60
FAQERRWKVAAAKKL	EP400	826	Q96L91
SEFLKRFVEATRKWK	ALDH8A1	301	Q9H2A2
KFTNKEWETIRSFKD	AASDHPPT	151	Q9NRN7
RDKLDIFRIEKLWKN	ASH1L	2696	Q9NR48
TKESKKEDLVFIFWA	CFL1	91	P23528
VSLKFRKNFWKLVKD	CXCR6	291	O00574
FLRIKWSKIEVDKNG	VCAN	61	P13611
TTLLRFSFWQEKILK	ADAM7	266	Q9H2U9
WSLFKEQKKNFERER	SSX2IP	436	Q9Y2D8
AFLKFKQRLEGLVWQ	ARHGEF37	331	A1IGU5
LQKFWRVTVKGFFVK	ARMH2	26	H3BNL8
NKFLVFKKKSDTWRL	FBXO10	891	Q9UK96
FNSRTKAFLKIIAVW	HTR2A	186	P28223
FEDVKVFWRVTLNKT	ADGRV1	5401	Q8WXG9
KKKLFWRAVVAEFLA	AQP1	6	P29972
EWFSETFQKVKEKLK	APOC1	66	P02654
FKWFELNQLKLEKDV	ABCA13	476	Q86UQ4
EKLFLVLFFDNKRTW	BRPF3	1131	Q9ULD4
KAVKREDLFIVSKLW	AKR1B10	66	O60218
VIDAKSFARIKKWLE	ALDH4A1	391	P30038
SKVDWGKFFLLKRFN	ALDH3A2	446	P51648
NFKVKRRWDDDVVFK	CWC15	181	Q9P013
WLLPVKLKKEFTVFE	ARRDC3	146	Q96B67
FAKKLEEKIRWLRAF	ARHGEF9	406	O43307
FRAEKKSLQIKEFIW	C16orf46	156	Q6P387
FERAKFWVKELRSLE	RAB24	96	Q969Q5
NFIRWEDKESKIFRI	ETV6	356	P41212
LVWEEFFDELKQTKR	MSANTD1	56	Q6ZTZ1
LVEKKTRKVWAGKFF	MYLK	1481	Q15746
GRFSWKDVNEKKVRF	FRAS1	1166	Q86XX4
RKREWFKVEDAIKVL	NUDT4B	116	A0A024RBG1
PFFKEIDWVLLEQKK	PRKCE	666	Q02156
FKIVGTKWLAKDLFL	DOP1B	91	Q9Y3R5
WFKKLSQKRFKQLVE	HECTD2	271	Q5U5R9
TKESKKEDLVFIFWA	CFL2	91	Q9Y281
VFFRQKWKDERLKFK	GABRA2	91	P47869
FDKIRVWLQSEKLER	ERAP1	926	Q9NZ08
IKSWAKRKFGFEENK	MND1	176	Q9BWT6
RFWKLYIEAEIKAKN	CSTF3	66	Q12996
LKDWQAFLDLKKRID	DNAH8	1326	Q96JB1
SKKLDFIILNETKFW	DPP4	511	P27487
VFFRQSWKDERLKFK	GABRA1	91	P14867
LFFQKINWDDLAAKK	RPS6KA5	316	O75582
FREKSLLIWIIGQKF	AP5M1	381	Q9H0R1
VVFIKWIVTFFLEKK	RALGAPA2	301	Q2PPJ7
ILFKDVNRKLSDVWK	MLKL	96	Q8NB16
KFFKKVIDANQREAW	OSBPL6	896	Q9BZF3
FLVKKWQEVDRKGAL	PCNT	3211	O95613
TKVSDFREWIFQAIK	HPN	391	P05981
EFRKLVRTFQKWLKE	MACF1	4331	Q9UPN3
ALFKAAEFAKLSIKW	PACC1	316	Q9H813
WKEFSKCLFIAQKIL	PARP14	551	Q460N5
EKTLFVKLSWNEKKF	ORC1	151	Q13415
DFLWKNKFKKEREEI	ADCY2	831	Q08462
EKFLFILSRKNLSVW	KLHL23	181	Q8NBE8
IWKQLYVASKKERFL	DOCK2	101	Q92608
FDWTQFRIISRLDKK	CHD6	1476	Q8TD26
LKIVKDGLIKWQEFF	AXDND1	481	Q5T1B0
LAEELKFKWENKVFT	DTHD1	756	Q6ZMT9
FKCDWFTLEKRVKLE	IRAG2	221	Q12912
SKSKKWFLELFEKNI	CYP39A1	216	Q9NYL5
FQKEVWTRLKAFAKL	ECI2	326	O75521
LSRAILDLVQFFKWK	GRIK2	156	Q13002
KIKKKYLRTWFVVDF	HCN2	281	Q9UL51
QFDKKILLWTGRFKS	FAM162B	71	Q5T6X4
HWFEKALRDKKGFII	OTUD5	201	Q96G74
LWFFLQSELKKLKNL	FUT8	126	Q9BYC5
NSIFLYLKWRVKKVV	TAS2R14	116	Q9NYV8
FIALVNSIEWFKRQK	TAS2R43	26	P59537
FIALVNSIEWFKRQK	TAS2R46	26	P59540
FIALVNFIDWVKRKK	TAS2R50	26	P59544
NFIDWVKRKKISSAD	TAS2R50	31	P59544
WFRKALKLTLSQKVF	TAAR5	311	O14804
KAEVNFWAETLIFVK	THADA	1831	Q6YHU6
FVKRQDWKKLLEFDQ	SYNJ2	741	O15056
KLWFKQKISKEEFDL	TADA1	31	Q96BN2
ELTHGEFKWQVKRKF	PLD1	106	Q13393
KIWEQSKKFSLFVRD	SAMD9	331	Q5K651
LLVLFWKLCDFNKKF	HID1	371	Q8IV36
SEFIELRKWLKARKF	SETD4	31	Q9NVD3
VFLLFAVICVWKEKK	ST6GAL1	16	P15907
TQFWRSKVLEVAKDF	PDIA4	431	P13667
RWKIFFAEEIKKSLI	MROH2B	1421	Q7Z745
WRSQLEKLAFKDKRL	CYB5R4	436	Q7L1T6
KAFVFLLSWIVLKDR	SLC35F4	286	A4IF30
IQLAKDFEDFRKKWQ	RACGAP1	31	Q9H0H5
FKLSKVWRDQHFVKI	TFRC	176	P02786
KTKEEDFLKLFDRWK	DZIP1	276	Q86YF9
SWKKQAEDIKKIFEF	CAMK1D	11	Q8IU85
KIRVALKDWDEVLKF	SNAPC1	96	Q16533
WLNKRLVFEKFTKES	SESTD1	156	Q86VW0
KKWAKFLRDFENFKA	TMC1	151	Q8TDI8
KRWLLEFAAKRKQAE	ACSL6	386	Q9UKU0
KVAAQKNFILKRLFW	C12orf56	356	Q8IXR9
KNFILKRLFWKTSDL	C12orf56	361	Q8IXR9
KEADRLNKSWEKRFF	C10orf67	431	Q8IYJ2
WAQLEKFLARKKFKL	SPATA4	111	Q8NEY3
KLAKFSFQIDRSWKA	SPG11	326	Q96JI7
KAFVELLFWKNTAVV	TIMELESS	786	Q9UNS1
EWKKERISKAFAVDI	SHF	206	Q7M4L6
DALKISIRQLKWKEF	TTLL11	231	Q8NHH1
FITEKAVFSRWAKKR	ST6GALNAC4	276	Q9H4F1
KVIKHWFRNTLFKER	ZFHX4	2126	Q86UP3
KDDIFLDLKQKFWNT	MPV17L	111	Q2QL34
KWSRRFFIIKESFLL	PLEKHD1	46	A6NEE1
NVLKLKTADWRVFLF	PSD2	591	Q9BQI7
FHWKQEELKFKTGLR	STAT6	121	P42226
KFPFWQKRIEKRNFT	ZBED8	411	Q8IZ13
RVKFNEALRESWKTK	PIK3CD	1016	O00329
VEFRNLLKWYAKEFK	TMEM97	41	Q5BJF2
EALKFLNKARKDSTW	TTC21A	1046	Q8NDW8
FIEKADAEEKWFKRL	RSRC1	306	Q96IZ7
LKFLCKDLWVAVFQK	TRAPPC6A	66	O75865
KAFKWSLIFNEHKRI	ZNF141	206	Q15928
LAFSKKQIDDRKEWL	TOP2A	651	P11388
RSWLIKFKNVLTFLE	SLC9C2	566	Q5TAH2
TLESFLAWKKRKRQE	ZC3H15	251	Q8WU90
EKEEWFRRFILASKL	TEX2	696	Q8IWB9
TVKQAKDKDRWIRLF	SMYD5	176	Q6GMV2
WKSFLLRRDAVNKIK	RNF145	506	Q96MT1
NKKAKIWRDTFLVER	SULF1	401	Q8IWU6
KDFINFISDKEWKSI	TMX1	121	Q9H3N1
FKLKTADWRVLLFQT	PSD3	866	Q9NYI0
KEIFRKNFFKDWRKE	TOP1	271	P11387
FRDVAVAFTQKEWKL	ZNF169	16	Q14929
LVKFWNSSDKEKIIR	L1TD1	761	Q5T7N2
DWIVANKDLIDKTKF	MYBPC1	781	Q00872