Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscell junction organization

TANC2 ANK3 NRCAM FNTA CDHR3 ITSN1 L1CAM SRC PERP CDH19 ZNF365 POF1B DLC1 PTPRD CLN3 IKBKB FYN TNR CDH6 CDH9

2.67e-0697412920GO:0034330
GeneOntologyBiologicalProcessregulation of caveolin-mediated endocytosis

ITSN1 SRC CLN3

8.21e-0671293GO:2001286
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

NRCAM CADM4 CDHR3 L1CAM CDH19 FAT1 CDH6 CDH9

2.35e-051871298GO:0007156
GeneOntologyBiologicalProcessadherens junction organization

CDHR3 SRC CDH19 CDH6 CDH9

3.98e-05611295GO:0034332
GeneOntologyBiologicalProcesscaveolin-mediated endocytosis

ITSN1 SRC CLN3

5.05e-05121293GO:0072584
GeneOntologyBiologicalProcesscell morphogenesis

TANC2 ANK3 NRCAM SZT2 CDHR3 L1CAM SRC CDH19 ZNF365 POF1B B4GALT5 FAT1 DLC1 PTPRD DIAPH2 FYN TNR CDH6 CDH9 SNX1

5.16e-05119412920GO:0000902
GeneOntologyBiologicalProcesscell-cell adhesion

IL12RB1 ANK3 NRCAM CADM4 CDHR3 L1CAM SRC PERP ADGRV1 CDH19 MMRN1 FAT1 PTPRD PLPP3 FYN TNR CDH6 CDH9

1.31e-04107712918GO:0098609
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

NRCAM CADM4 CDHR3 L1CAM CDH19 FAT1 PTPRD CDH6 CDH9

1.59e-043131299GO:0098742
GeneOntologyBiologicalProcesscell-cell junction organization

CDHR3 SRC PERP CDH19 POF1B IKBKB CDH6 CDH9

1.61e-042461298GO:0045216
GeneOntologyCellularComponentanchoring junction

ANK3 CADM4 CDHR3 L1CAM SRC PERP CDH19 POF1B RHO FAT1 TADA1 DLC1 PLPP3 SH3PXD2A PIK3R2 CLTC CDH6 CDH9 ARHGEF6

8.65e-0697612919GO:0070161
GeneOntologyCellularComponentextrinsic component of membrane

CDHR3 CDH19 TAMM41 PIK3R2 CLTC GNAO1 CDH6 CDH9 SNX1

1.32e-052301299GO:0019898
GeneOntologyCellularComponentcatenin complex

CDHR3 CDH19 CDH6 CDH9

4.35e-05321294GO:0016342
GeneOntologyCellularComponentactin cytoskeleton

ACACA ITSN1 MAEA SRC VPS16 NEB POF1B DLC1 VILL SH3PXD2A SCNN1A DIAPH2 FYN

5.86e-0557612913GO:0015629
GeneOntologyCellularComponentKICSTOR complex

ITFG2 SZT2

2.25e-0441292GO:0140007
GeneOntologyCellularComponentUSH2 complex

ADGRV1 USH2A

2.25e-0441292GO:1990696
GeneOntologyCellularComponentphotoreceptor cell cilium

OPN3 ADGRV1 RHO EYS ATP1A4 USH2A

2.26e-041391296GO:0097733
GeneOntologyCellularComponentactin filament

SRC VPS16 POF1B DLC1 DIAPH2 FYN

2.94e-041461296GO:0005884
GeneOntologyCellularComponentcell-cell junction

ANK3 CADM4 CDHR3 PERP CDH19 POF1B RHO FAT1 PLPP3 CDH6 CDH9 ARHGEF6

3.02e-0459112912GO:0005911
GeneOntologyCellularComponent9+0 non-motile cilium

OPN3 ADGRV1 RHO EYS ATP1A4 USH2A

3.78e-041531296GO:0097731
GeneOntologyCellularComponentpostsynaptic specialization, intracellular component

TANC2 SRC FYN SNX1

3.97e-04561294GO:0099091
GeneOntologyCellularComponentstereocilia ankle link

ADGRV1 USH2A

5.58e-0461292GO:0002141
GeneOntologyCellularComponentstereocilia ankle link complex

ADGRV1 USH2A

5.58e-0461292GO:0002142
GeneOntologyCellularComponentstereocilium membrane

ADGRV1 USH2A

5.58e-0461292GO:0060171
GeneOntologyCellularComponentpericiliary membrane compartment

ADGRV1 USH2A

5.58e-0461292GO:1990075
GeneOntologyCellularComponentstereocilia coupling link

ADGRV1 USH2A

1.03e-0381292GO:0002139
GeneOntologyCellularComponentcell leading edge

CADM4 ITSN1 SRC ADGRV1 FAT1 BMX DLC1 USH2A SNX1 ARHGEF6

1.09e-0350012910GO:0031252
GeneOntologyCellularComponentrod photoreceptor outer segment

RHO ATP1A4

1.32e-0391292GO:0120200
GeneOntologyCellularComponentclathrin complex

CLTCL1 CLTC

1.32e-0391292GO:0071439
GeneOntologyCellularComponentnon-motile cilium

OPN3 ADGRV1 RHO EYS ATP1A4 USH2A

1.38e-031961296GO:0097730
GeneOntologyCellularComponentcell projection membrane

TRPM6 SRC TSPEAR ADGRV1 RHO BMX DLC1 SCNN1A USH2A

1.44e-034311299GO:0031253
GeneOntologyCellularComponentextrinsic component of plasma membrane

CDHR3 CDH19 GNAO1 CDH6 CDH9

1.62e-031371295GO:0019897
GeneOntologyCellularComponentglutamatergic synapse

TANC2 NRCAM ITSN1 L1CAM SRC PTPRD CLTC GNAO1 CPNE4 FYN TNR CDH6 CDH9

1.64e-0381712913GO:0098978
GeneOntologyCellularComponentmembrane raft

SRC DLC1 PLPP3 CLN3 IKBKB ATP1A4 FYN TNR

1.86e-033621298GO:0045121
GeneOntologyCellularComponentmembrane microdomain

SRC DLC1 PLPP3 CLN3 IKBKB ATP1A4 FYN TNR

1.92e-033641298GO:0098857
GeneOntologyCellularComponentadherens junction

CDHR3 CDH19 POF1B PLPP3 CDH6 CDH9

2.05e-032121296GO:0005912
GeneOntologyCellularComponentextrinsic component of organelle membrane

TAMM41 CLTC SNX1

2.37e-03431293GO:0031312
GeneOntologyCellularComponentdendritic growth cone

L1CAM SRC

2.40e-03121292GO:0044294
GeneOntologyCellularComponentextracellular matrix

NID2 MXRA5 COL12A1 L1CAM MMRN1 EYS CELA1 TNR USH2A MUC5AC OTOG

2.51e-0365612911GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

NID2 MXRA5 COL12A1 L1CAM MMRN1 EYS CELA1 TNR USH2A MUC5AC OTOG

2.56e-0365812911GO:0030312
GeneOntologyCellularComponentmitotic spindle microtubule

HAUS4 CLTC

3.28e-03141292GO:1990498
GeneOntologyCellularComponentplasma membrane protein complex

IL12RB1 CDHR3 CDH19 TGFBR3 CLTC C5 GNAO1 IKBKB ATP1A4 TRAV40 CDH6 CDH9

3.42e-0378512912GO:0098797
GeneOntologyCellularComponentpostsynaptic density, intracellular component

TANC2 FYN SNX1

3.44e-03491293GO:0099092
DomainFN3

IL12RB1 COL12A1 NRCAM L1CAM LEPR IFNGR2 PTPRD TNR USH2A

4.91e-061851279SM00060
DomainFN3

IL12RB1 COL12A1 NRCAM L1CAM LEPR IFNGR2 PTPRD TNR USH2A

8.86e-061991279PS50853
DomainFN3_dom

IL12RB1 COL12A1 NRCAM L1CAM LEPR IFNGR2 PTPRD TNR USH2A

1.31e-052091279IPR003961
Domainfn3

IL12RB1 COL12A1 NRCAM L1CAM IFNGR2 PTPRD TNR USH2A

1.51e-051621278PF00041
DomainClathrin_H-chain_propeller_rpt

CLTCL1 CLTC

4.59e-0521272IPR022365
DomainClathrin-link

CLTCL1 CLTC

4.59e-0521272PF09268
Domain-

CLTCL1 CLTC

4.59e-05212722.130.10.110
DomainClathrin_heavy_chain

CLTCL1 CLTC

4.59e-0521272IPR016341
DomainClathrin_H-chain_propeller_N

CLTCL1 CLTC

4.59e-0521272IPR001473
DomainClathrin_H-chain_link/propller

CLTCL1 CLTC

4.59e-0521272IPR016025
DomainClathrin_propel

CLTCL1 CLTC

4.59e-0521272PF01394
DomainClathrin_H-chain_linker_core

CLTCL1 CLTC

4.59e-0521272IPR015348
DomainLaminin_G

COL12A1 TSPEAR EYS FAT1 USH2A

4.61e-05581275IPR001791
DomainSH3_1

ITSN1 SRC NEB SH3PXD2A PIK3R2 FYN ARHGEF6

1.31e-041641277PF00018
DomainClathrin_H-chain_linker

CLTCL1 CLTC

1.37e-0431272IPR012331
DomainCLH

CLTCL1 CLTC

1.37e-0431272SM00299
DomainLamG

TSPEAR EYS FAT1 USH2A

2.24e-04441274SM00282
DomainNeurofascin/L1/NrCAM_C

NRCAM L1CAM

2.73e-0441272IPR026966
DomainBravo_FIGEY

NRCAM L1CAM

2.73e-0441272PF13882
DomainNuc_sug_transp

SLC35A1 SLC35A4

4.53e-0451272PF04142
DomainNuc_sug_transpt

SLC35A1 SLC35A4

4.53e-0451272IPR007271
Domain-

COL12A1 ADGRV1 EYS FAT1 USH2A

4.77e-049512752.60.120.200
DomainCadherin_C

CDH19 CDH6 CDH9

6.33e-04251273PF01049
DomainCadherin_cytoplasmic-dom

CDH19 CDH6 CDH9

6.33e-04251273IPR000233
DomainEPTP

TSPEAR ADGRV1

6.76e-0461272PF03736
DomainEPTP

TSPEAR ADGRV1

6.76e-0461272IPR005492
DomainSH3

ITSN1 SRC NEB SH3PXD2A PIK3R2 FYN ARHGEF6

6.95e-042161277SM00326
DomainSH3

ITSN1 SRC NEB SH3PXD2A PIK3R2 FYN ARHGEF6

6.95e-042161277PS50002
DomainConA-like_dom

COL12A1 TSPEAR ADGRV1 MMRN1 EYS FAT1 USH2A

7.53e-042191277IPR013320
DomainSH3_domain

ITSN1 SRC NEB SH3PXD2A PIK3R2 FYN ARHGEF6

7.74e-042201277IPR001452
DomainClathrin

CLTCL1 CLTC

9.42e-0471272PF00637
DomainHematopoietin_rcpt_Gp130_CS

IL12RB1 LEPR

9.42e-0471272IPR003529
DomainEAR

TSPEAR ADGRV1

9.42e-0471272IPR009039
DomainEAR

TSPEAR ADGRV1

9.42e-0471272PS50912
DomainCHCR

CLTCL1 CLTC

9.42e-0471272PS50236
DomainCatenin_binding_dom

CDH19 CDH6 CDH9

9.86e-04291273IPR027397
Domain-

CDH19 CDH6 CDH9

9.86e-042912734.10.900.10
DomainCADHERIN_1

CDHR3 CDH19 FAT1 CDH6 CDH9

1.05e-031131275PS00232
DomainCadherin

CDHR3 CDH19 FAT1 CDH6 CDH9

1.05e-031131275PF00028
DomainCADHERIN_2

CDHR3 CDH19 FAT1 CDH6 CDH9

1.09e-031141275PS50268
Domain-

CDHR3 CDH19 FAT1 CDH6 CDH9

1.09e-0311412752.60.40.60
DomainCA

CDHR3 CDH19 FAT1 CDH6 CDH9

1.14e-031151275SM00112
DomainEGF_3

NID2 ADAM32 MMRN1 EYS FAT1 TNR OTOG

1.14e-032351277PS50026
DomainCadherin-like

CDHR3 CDH19 FAT1 CDH6 CDH9

1.18e-031161275IPR015919
DomainClathrin_H-chain/VPS_repeat

CLTCL1 CLTC

1.25e-0381272IPR000547
DomainHEMATOPO_REC_L_F2

IL12RB1 LEPR

1.25e-0381272PS01353
DomainRetinal_BS

OPN3 RHO

1.25e-0381272IPR027430
DomainCadherin

CDHR3 CDH19 FAT1 CDH6 CDH9

1.27e-031181275IPR002126
DomainEGF-like_dom

NID2 ADAM32 MMRN1 EYS FAT1 TNR OTOG

1.58e-032491277IPR000742
Domain-

IL12RB1 MXRA5 COL12A1 NRCAM CADM4 L1CAM LEPR EBF2 IFNGR2 PTPRD TNR USH2A

1.89e-03663127122.60.40.10
DomainOPSIN

OPN3 RHO

1.99e-03101272PS00238
DomainLAM_G_DOMAIN

EYS FAT1 USH2A

2.18e-03381273PS50025
DomainOpsin

OPN3 RHO

2.42e-03111272IPR001760
DomainLaminin_G_2

EYS FAT1 USH2A

2.52e-03401273PF02210
DomainSSF

SLC5A10 SLC5A12

2.90e-03121272PF00474
DomainC8

MUC5AC OTOG

2.90e-03121272PF08742
DomainTIL

MUC5AC OTOG

2.90e-03121272PF01826
DomainNA_SOLUT_SYMP_2

SLC5A10 SLC5A12

2.90e-03121272PS00457
DomainNa/solute_symporter

SLC5A10 SLC5A12

2.90e-03121272IPR001734
DomainNA_SOLUT_SYMP_3

SLC5A10 SLC5A12

2.90e-03121272PS50283
DomainIg-like_fold

IL12RB1 MXRA5 COL12A1 NRCAM CADM4 L1CAM LEPR EBF2 IFNGR2 PTPRD TNR USH2A

3.16e-0370612712IPR013783
DomainUnchr_dom_Cys-rich

MUC5AC OTOG

3.41e-03131272IPR014853
DomainC8

MUC5AC OTOG

3.41e-03131272SM00832
DomainTIL_dom

MUC5AC OTOG

3.96e-03141272IPR002919
DomainPROTEIN_KINASE_TYR

NEK10 SRC BMX FYN

4.34e-03971274PS00109
DomainTyr_kinase_AS

NEK10 SRC BMX FYN

4.34e-03971274IPR008266
DomainSH2

SRC BMX PIK3R2 FYN

5.01e-031011274PF00017
DomainVWF_type-D

MUC5AC OTOG

5.17e-03161272IPR001846
DomainVWFD

MUC5AC OTOG

5.17e-03161272PS51233
DomainVWD

MUC5AC OTOG

5.17e-03161272SM00216
DomainVWD

MUC5AC OTOG

5.17e-03161272PF00094
DomainSushi

CSMD3 CFHR3 CSMD1

5.32e-03521273PF00084
DomainEGF

NID2 ADAM32 MMRN1 EYS FAT1 TNR

5.44e-032351276SM00181
DomainCCP

CSMD3 CFHR3 CSMD1

5.92e-03541273SM00032
DomainEGF-type_Asp/Asn_hydroxyl_site

NID2 MMRN1 EYS FAT1

5.94e-031061274IPR000152
DomainSUSHI

CSMD3 CFHR3 CSMD1

6.55e-03561273PS50923
DomainCadherin_CS

CDH19 FAT1 CDH6 CDH9

6.55e-031091274IPR020894
DomainSH2

SRC BMX PIK3R2 FYN

6.76e-031101274SM00252
PathwayWP_LEPTIN_SIGNALING

ACACA SRC LEPR PIK3R2 IKBKB FYN

1.51e-0576996M39491
Pubmed

Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.

ITSN1 SRC NEB PIK3R2 FYN

6.19e-0828130518067320
Pubmed

The Tom1L1-clathrin heavy chain complex regulates membrane partitioning of the tyrosine kinase Src required for mitogenic and transforming activities.

SRC CLTC FYN

5.08e-075130317785434
Pubmed

Mouse disabled (mDab1): a Src binding protein implicated in neuronal development.

SRC LEPR FYN

1.01e-06613039009273
Pubmed

p59fyn and pp60c-src modulate axonal guidance in the developing mouse olfactory pathway.

L1CAM SRC FYN

1.01e-06613039658338
Pubmed

Whirlin replacement restores the formation of the USH2 protein complex in whirlin knockout photoreceptors.

ADGRV1 RHO USH2A

1.77e-067130321212183
Pubmed

Novel Phosphorylations of IKKγ/NEMO.

SRC IKBKB FYN

1.77e-067130323131831
Pubmed

Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome.

SRC SH3PXD2A FYN ARHGEF6

2.22e-0625130416374509
Pubmed

Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.

SRC PTPRD FYN

2.82e-068130328637841
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NMNAT2 ACACA ANK3 NSD2 MAEA SRC CPD RABGAP1 ADGRV1 HPS3 USP10 SLC35A4 SH3PXD2A SCNN1A ZFHX3 ANKRD12 GREB1 UBE3C CSMD1

2.92e-0614891301928611215
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ACACA ANK3 CADM4 SRC CPD RALGAPA2 ARHGAP5 TAMM41 PIK3R2 SNX1

4.45e-064211301036976175
Pubmed

The adapter protein Grb10 associates preferentially with the insulin receptor as compared with the IGF-I receptor in mouse fibroblasts.

SRC PIK3R2 FYN

6.01e-061013039062339
Pubmed

Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy.

CDH19 CDH6 CDH9

1.10e-0512130322102170
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

NMNAT2 SLC36A4 CDHR3 MAEA SLC35A1 ADGRV1 IFNGR2 DLC1 PTPRD CELA1 GREB1 CSMD1 TRAV40

1.22e-058141301323251661
Pubmed

Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell-cell fusion.

SRC SH3PXD2A

1.39e-052130222584907
Pubmed

Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.

SRC FYN

1.39e-05213028681387
Pubmed

Deficiency of Fyn protein is prerequisite for apoptosis induced by Src family kinase inhibitors in human mesothelioma cells.

SRC FYN

1.39e-052130222354875
Pubmed

Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke.

SRC FYN

1.39e-052130211175854
Pubmed

Microexon-based regulation of ITSN1 and Src SH3 domains specificity relies on introduction of charged amino acids into the interaction interface.

ITSN1 SRC

1.39e-052130220659428
Pubmed

Cutaneous Epithelial to Mesenchymal Transition Activator ZEB1 Regulates Wound Angiogenesis and Closure in a Glycemic Status-Dependent Manner.

ZEB1 LEPR

1.39e-052130231439646
Pubmed

c-Src but not Fyn promotes proper spindle orientation in early prometaphase.

SRC FYN

1.39e-052130222689581
Pubmed

Disease expression in Usher syndrome caused by VLGR1 gene mutation (USH2C) and comparison with USH2A phenotype.

ADGRV1 USH2A

1.39e-052130215671307
Pubmed

Syndromic and non-syndromic forms of retinitis pigmentosa: a comprehensive Italian clinical and molecular study reveals new mutations.

RHO EYS

1.39e-052130225366773
Pubmed

Characteristics of Retinitis Pigmentosa Associated with ADGRV1 and Comparison with USH2A in Patients from a Multicentric Usher Syndrome Study Treatrush.

ADGRV1 USH2A

1.39e-052130234638692
Pubmed

Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.

CLTCL1 CLTC

1.39e-05213028733129
Pubmed

Overlapping functions of the cell adhesion molecules Nr-CAM and L1 in cerebellar granule cell development.

NRCAM L1CAM

1.39e-052130211564762
Pubmed

A Src-Tks5 pathway is required for neural crest cell migration during embryonic development.

SRC SH3PXD2A

1.39e-052130221799874
Pubmed

Usher's Syndrome Type II: A Comparative Study of Genetic Mutations and Vestibular System Evaluation.

ADGRV1 USH2A

1.39e-052130228653555
Pubmed

CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.

CLTCL1 CLTC

1.39e-052130229097553
Pubmed

Tumor metastasis but not tumor growth is dependent on Src-mediated vascular permeability.

SRC FYN

1.39e-052130215486073
Pubmed

A new method for isolating tyrosine kinase substrates used to identify fish, an SH3 and PX domain-containing protein, and Src substrate.

SRC SH3PXD2A

1.39e-05213029687503
Pubmed

The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.

CLTCL1 CLTC

1.39e-052130220065094
Pubmed

Subcellular localization of ATBF1 regulates MUC5AC transcription in gastric cancer.

ZFHX3 MUC5AC

1.39e-052130217330845
Pubmed

Mapping of the gene coding for the muscle protein nebulin (Neb) to the proximal region of mouse chromosome 2.

NEB C5

1.39e-05213021683831
Pubmed

Tks5 SH3 domains exhibit differential effects on invadopodia development.

SRC SH3PXD2A

1.39e-052130231999741
Pubmed

Molecular and biochemical characterization of a novel gamma-interferon-inducible protein.

IFNGR2 IFI30

1.39e-05213023136170
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

COL12A1 ACACA L1CAM CPD URB2 DMAP1 USP10 FAT1 TAMM41 CLTC IFI30 UBE3C IKBKB FYN SNX1 ATPAF1

2.86e-0512971301633545068
Pubmed

Identification of novel human WW domain-containing proteins by cloning of ligand targets.

SRC SCNN1A FYN

4.00e-051813039169421
Pubmed

Vasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3.

USP10 SCNN1A

4.15e-053130218632802
Pubmed

Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation.

SRC FYN

4.15e-053130212089510
Pubmed

Identification of two new members of the CSMD gene family.

CSMD3 CSMD1

4.15e-053130212906867
Pubmed

Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.

CLTCL1 CLTC

4.15e-053130219509056
Pubmed

PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome.

ADGRV1 USH2A

4.15e-053130220440071
Pubmed

XB130/Tks5 scaffold protein interaction regulates Src-mediated cell proliferation and survival.

SRC SH3PXD2A

4.15e-053130226446840
Pubmed

Localized activation of Src-family protein kinases in the mouse egg.

SRC FYN

4.15e-053130217449027
Pubmed

Activation of Src, Fyn and Yes non-receptor tyrosine kinases in keratinocytes expressing human papillomavirus (HPV) type 16 E7 oncoprotein.

SRC FYN

4.15e-053130223497302
Pubmed

Differential transformation capacity of Src family kinases during the initiation of prostate cancer.

SRC FYN

4.15e-053130221464326
Pubmed

Lithium reduced N-methyl-D-aspartate receptor subunit 2A tyrosine phosphorylation and its interactions with Src and Fyn mediated by PSD-95 in rat hippocampus following cerebral ischemia.

SRC FYN

4.15e-053130212932824
Pubmed

Dystroglycan, Tks5 and Src mediated assembly of podosomes in myoblasts.

SRC SH3PXD2A

4.15e-053130218982058
Pubmed

Requirement of SRC-family tyrosine kinases in fat accumulation.

SRC FYN

4.15e-053130216262245
Pubmed

Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk.

SRC FYN

4.15e-053130211353545
Pubmed

USP10 Regulates ZEB1 Ubiquitination and Protein Stability to Inhibit ZEB1-Mediated Colorectal Cancer Metastasis.

ZEB1 USP10

4.15e-053130236940483
Pubmed

The F3 neuronal glycosylphosphatidylinositol-linked molecule is localized to glycolipid-enriched membrane subdomains and interacts with L1 and fyn kinase in cerebellum.

L1CAM FYN

4.15e-05313027595520
Pubmed

Src promotes EGF-induced epithelial-to-mesenchymal transition and migration in gastric cancer cells by upregulating ZEB1 and ZEB2 through AKT.

ZEB1 SRC

4.15e-053130229052277
Pubmed

Nr-CAM expression in the developing mouse nervous system: ventral midline structures, specific fiber tracts, and neuropilar regions.

NRCAM L1CAM

4.15e-053130211329126
Pubmed

DIAPH2, PTPRD and HIC1 Gene Polymorphisms and Laryngeal Cancer Risk.

PTPRD DIAPH2

4.15e-053130234299935
Pubmed

A juxtamembrane tyrosine in the colony stimulating factor-1 receptor regulates ligand-induced Src association, receptor kinase function, and down-regulation.

SRC FYN

4.15e-053130215297464
Pubmed

Disease-related modifications in tau affect the interaction between Fyn and Tau.

SRC FYN

4.15e-053130216115884
Pubmed

L1 coupling to ankyrin and the spectrin-actin cytoskeleton modulates ethanol inhibition of L1 adhesion and ethanol teratogenesis.

ANK3 L1CAM

4.15e-053130229109170
Pubmed

Specific and redundant roles of Src and Fyn in organizing the cytoskeleton.

SRC FYN

4.15e-05313027617039
Pubmed

Differential requirement for Src family tyrosine kinases in the initiation, progression, and metastasis of prostate cancer.

SRC FYN

4.15e-053130225053806
Pubmed

Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.

LEPR MUC5AC

4.15e-053130220422702
Pubmed

The ubiquitination of CKIP-1 mediated by Src aggravates diabetic renal fibrosis (original article).

SRC LEPR

4.15e-053130236347273
Pubmed

Non-USH2A mutations in USH2 patients.

ADGRV1 USH2A

4.15e-053130222147658
Pubmed

H-Ras modulates N-methyl-D-aspartate receptor function via inhibition of Src tyrosine kinase activity.

SRC FYN

4.15e-053130212695509
Pubmed

Elevation of Hook1 in a disease model of Batten disease does not affect a novel interaction between Ankyrin G and Hook1.

ANK3 CLN3

4.15e-053130215823567
Pubmed

Src family kinases are required for integrin but not PDGFR signal transduction.

SRC FYN

4.15e-053130210228160
Pubmed

Raf-1 interacts with Fyn and Src in a non-phosphotyrosine-dependent manner.

SRC FYN

4.15e-05313027517401
Pubmed

Cadherins Interact With Synaptic Organizers to Promote Synaptic Differentiation.

CDH6 CDH9

4.15e-053130229760652
Pubmed

Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation.

SRC BMX

4.15e-053130210688651
Pubmed

Genetic disruption of the sh3pxd2a gene reveals an essential role in mouse development and the existence of a novel isoform of tks5.

SRC SH3PXD2A

4.15e-053130225259869
Pubmed

Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice.

SRC FYN

4.15e-05313027958873
Pubmed

Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG.

CLTCL1 CLTC

4.15e-053130222891263
Pubmed

Critical roles of Src family tyrosine kinases in excitatory neuronal differentiation of cultured embryonic stem cells.

SRC FYN

4.15e-053130216859680
Pubmed

Src, Fyn and Yes play differential roles in VEGF-mediated endothelial cell events.

SRC FYN

4.15e-053130216400523
Pubmed

Loss of p53 enhances catalytic activity of IKKbeta through O-linked beta-N-acetyl glucosamine modification.

LEPR IKBKB

4.15e-053130219202066
Pubmed

Bergmann glia and the recognition molecule CHL1 organize GABAergic axons and direct innervation of Purkinje cell dendrites.

NRCAM L1CAM

4.15e-053130218447583
Pubmed

Anthrax toxin triggers the activation of src-like kinases to mediate its own uptake.

SRC FYN

4.15e-053130220080640
Pubmed

Entry of Neisseria meningitidis into mammalian cells requires the Src family protein tyrosine kinases.

SRC FYN

4.15e-053130220176789
Pubmed

Tyrosine phosphorylation of the N-methyl-D-aspartate receptor by exogenous and postsynaptic density-associated Src-family kinases.

SRC FYN

4.15e-053130211483655
Pubmed

Protein tyrosine phosphatase PTP20 induces actin cytoskeleton reorganization by dephosphorylating p190 RhoGAP in rat ovarian granulosa cells stimulated with follicle-stimulating hormone.

SRC ARHGAP5

4.15e-053130212554790
Pubmed

Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients.

SRC FYN

4.15e-053130219690143
Pubmed

SRC and TKS5 mediated podosome formation in fibroblasts promotes extracellular matrix invasion and pulmonary fibrosis.

SRC SH3PXD2A

4.15e-053130237735172
Pubmed

BMP2 rescues deficient cell migration in Tgfbr3(-/-) epicardial cells and requires Src kinase.

SRC TGFBR3

4.15e-053130226645362
Pubmed

Targeted next generation sequencing in Italian patients with Usher syndrome: phenotype-genotype correlations.

ADGRV1 USH2A

4.15e-053130229142287
Pubmed

Non-receptor tyrosine kinases in mammalian neurogenesis.

SRC FYN

4.15e-05313028983085
Pubmed

Cdk5-dependent regulation of Rho activity, cytoskeletal contraction, and epithelial cell migration via suppression of Src and p190RhoGAP.

SRC ARHGAP5

4.15e-053130219822667
Pubmed

Regulation of TRPC6 channel activity by tyrosine phosphorylation.

SRC FYN

4.15e-053130214761972
Pubmed

Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration.

CLTCL1 CLTC

4.15e-053130215133132
Pubmed

Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability.

SRC FYN

4.15e-053130210635317
Pubmed

Missing-in-Metastasis regulates cell motility and invasion via PTPδ-mediated changes in SRC activity.

SRC PTPRD

4.15e-053130225287652
Pubmed

Characterization of Fyn-mediated tyrosine phosphorylation sites on GluR epsilon 2 (NR2B) subunit of the N-methyl-D-aspartate receptor.

SRC FYN

4.15e-053130211024032
Pubmed

The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1.

ADGRV1 USH2A

4.15e-053130216434480
Pubmed

Feed-forward signaling of TNF-alpha and NF-kappaB via IKK-beta pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice.

LEPR IKBKB

4.15e-053130219363130
Pubmed

Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome.

ITSN1 SRC SH3PXD2A FYN

5.89e-0556130422745667
Pubmed

Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.

IL12RB1 DLC1 PTPRD EHHADH IFI30 GREB1 CSMD1

6.56e-05265130719240061
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TANC2 ZEB1 ANK3 NRCAM ITSN1 SRC USP10 PTPRD PLPP3 CLTC DIAPH2 GNAO1 TNR

6.87e-059631301328671696
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TANC2 CLTCL1 ACACA SZT2 VWA8 NSD2 MAEA L1CAM RALGAPA2 HAUS4 FAT1 CLN3 DIAPH2 UBE3C

7.03e-0511051301435748872
Pubmed

Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2.

RHO GNAO1 UBE3C

7.46e-0522130318460603
Pubmed

EG-1 interacts with c-Src and activates its signaling pathway.

SRC PIK3R2 FYN

7.46e-0522130316964398
Pubmed

RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef.

SRC FYN

8.28e-05413029778343
Cytoband4p16.3

NSD2 MAEA ZFYVE28 OTOP1

1.04e-048513044p16.3
GeneFamilyFibronectin type III domain containing

IL12RB1 COL12A1 NRCAM L1CAM IFNGR2 PTPRD TNR USH2A

1.21e-06160898555
GeneFamilyCD molecules|Type II classical cadherins

CDH19 CDH6 CDH9

3.18e-05138931186
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZEB1 ZFHX3 TSHZ1

5.03e-0515893529
GeneFamilyFibronectin type III domain containing|USH2 complex

ADGRV1 USH2A

1.43e-0448921244
GeneFamilyOpsin receptors

OPN3 RHO

1.28e-0311892215
GeneFamilySH2 domain containing

SRC BMX PIK3R2 FYN

1.56e-03101894741
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CSMD3 CFHR3 CSMD1

2.78e-03578931179
GeneFamilyCadherin related

CDHR3 FAT1

3.11e-031789224
CoexpressionIKEDA_MIR133_TARGETS_UP

RABGAP1 EBF2 PTPRD ANKRD12 SNX1

2.39e-06441285M2377
CoexpressionIKEDA_MIR133_TARGETS_UP

RABGAP1 EBF2 PTPRD ANKRD12 SNX1

2.68e-06451285MM929
CoexpressionNABA_ECM_GLYCOPROTEINS

NID2 MXRA5 TSPEAR MMRN1 EYS TNR USH2A OTOG

5.63e-061961288M3008
CoexpressionGSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP

TANC2 ACACA ITFG2 VWA8 DNAJC30 URB2 RALGAPA2 DIAPH2

5.85e-061971288M7403
CoexpressionGSE30971_WBP7_HET_VS_KO_MACROPHAGE_4H_LPS_STIM_DN

OGFRL1 ITFG2 SLC35A1 NHLRC3 HPS3 ZFHX3 C5 ARHGEF6

5.85e-061971288M8726
CoexpressionNABA_CORE_MATRISOME

NID2 MXRA5 COL12A1 TSPEAR MMRN1 EYS TNR USH2A OTOG

8.68e-062751289M5884
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN

TANC2 ANK3 NRCAM NSD2 RFTN2 ZNF365 B4GALT5 TGFBR3 ARHGAP5 RNASEL CELA1 ZFHX3 ANKRD12 GNAO1 FYN TNR ATPAF1

2.68e-05110212817M2369
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN

TANC2 ANK3 NRCAM NSD2 RFTN2 ZNF365 B4GALT5 TGFBR3 ARHGAP5 RNASEL CELA1 ZFHX3 ANKRD12 GNAO1 FYN TNR ATPAF1

3.44e-05112412817MM1070
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA

NMNAT2 ANK3 L1CAM NEB EBF2 SH3PXD2A ZFHX3 ANKRD12 GNAO1 CPNE4 CSMD1

3.98e-0550612811M39067
CoexpressionGSE18893_TCONV_VS_TREG_2H_TNF_STIM_DN

TANC2 OGFRL1 SLC35A1 CPD RABGAP1 ZFYVE28 ANKRD12

4.85e-051941287M7306
CoexpressionGSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP

ANK3 OR2H1 CDH19 ZNF365 LEPR B4GALT5 PLPP3

5.18e-051961287M8135
CoexpressionGSE37301_COMMON_LYMPHOID_PROGENITOR_VS_RAG2_KO_NK_CELL_DN

OGFRL1 ZEB1 OPN3 L1CAM CDH19 IFNGR2 DIAPH2

5.52e-051981287M8874
CoexpressionGSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_UP

NID2 MXRA5 B4GALT5 PLPP3 DIAPH2 IFI30 TNR

5.70e-051991287M8390
CoexpressionMURARO_PANCREAS_BETA_CELL

TANC2 NMNAT2 NRCAM PERP CPD TGFBR3 ARHGAP5 CLTC TSHZ1 ANKRD12 GNAO1 UBE3C DHRS2 FYN ZNF292

6.08e-0594612815M39169
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 AOX1 PTPRD EHHADH GREB1 SLC5A12 CPNE4 CSMD1 CDH6 CDH9

6.15e-12182129114a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 NRCAM ADGRV1 NEB CSMD3 FAT1 PTPRD CSMD1 ATP1A4 USH2A OTOG

6.93e-12184129112cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 NRCAM ADGRV1 NEB CSMD3 FAT1 PTPRD CSMD1 ATP1A4 USH2A OTOG

6.93e-1218412911ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 NRCAM ADGRV1 NEB CSMD3 FAT1 PTPRD CSMD1 ATP1A4 USH2A OTOG

6.93e-12184129112b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 AOX1 EHHADH GREB1 SLC5A12 CPNE4 CSMD1 CDH9

2.51e-0917712992f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 PTPRD EHHADH GREB1 SLC5A12 CSMD1 CDH6 CDH9

3.21e-091821299e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 PTPRD EHHADH GREB1 SLC5A12 CSMD1 CDH6 CDH9

3.21e-09182129957bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC5A10 NRCAM CDHR3 AOX1 FAT1 PTPRD EHHADH CDH6 CDH9

3.37e-0918312996878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

ZEB1 AOX1 CDH19 EBF2 TGFBR3 EYS PTPRD ZFHX3 FYN

4.90e-09191129970c067c54084bfb02c29bab085f4defd477194fb
ToppCell10x3'2.3-week_17-19-Neuro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NID2 ANK3 CADM4 L1CAM CDH19 ZNF365 SLC5A12 CDH6

4.56e-081751298bbce8b1a160b414c0bf643c21c4e5e78fbccb7e1
ToppCell10x3'2.3-week_17-19-Neuro-stroma-schwann_cells|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NID2 ANK3 CADM4 L1CAM CDH19 ZNF365 SLC5A12 CDH6

4.56e-0817512988b010220cdfb680ec839572f4933adfb85045ea6
ToppCell10x3'2.3-week_17-19-Neuro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NID2 ANK3 CADM4 L1CAM CDH19 ZNF365 SLC5A12 CDH6

4.56e-0817512980b579aeadcc06be83627391c0b01bd8605fdbdf3
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

CDHR3 AOX1 FAT1 PTPRD EHHADH SLC5A12 CDH6 CDH9

5.67e-081801298864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 CADM4 CDH19 CSMD3 ZFYVE28 OTOP1 GREB1 DHRS2

6.17e-081821298a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 AOX1 EHHADH SLC5A12 CPNE4 CSMD1 CDH9

6.44e-08183129885446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

SLC5A10 CDHR3 AOX1 PTPRD EHHADH SLC5A12 CDH6 CDH9

6.72e-081841298dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 SZT2 CADM4 L1CAM CDH19 MMRN1 CELA1 CSMD1

6.72e-081841298e33bb572af9dfd11127105f1ac99bc958a7cafbb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 AOX1 PTPRD EHHADH SLC5A12 CDH6 CDH9

7.30e-0818612988287146f0ba415ea04475588117d4668ae00f75c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 PTPRD GREB1 SLC5A12 CPNE4 CSMD1 CDH9

7.30e-081861298a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 AOX1 PTPRD EHHADH SLC5A12 CDH6 CDH9

7.61e-08187129871eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 AOX1 PTPRD EHHADH SLC5A12 CDH6 CDH9

7.61e-081871298dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 AOX1 PTPRD EHHADH SLC5A12 CDH6 CDH9

7.61e-081871298f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

ZEB1 AOX1 LEPR EBF2 FAT1 PTPRD SH3PXD2A GNAO1

8.26e-0818912983922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

ZEB1 RALGAPA2 LEPR B4GALT5 MMRN1 BMX DLC1 PLPP3

8.26e-081891298c81787a8c662db5d7814c583dd64562857629e81
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 CADM4 L1CAM CDH19 CSMD3 CELA1 DHRS2 CSMD1

8.60e-081901298ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 CADM4 L1CAM CDH19 CSMD3 CELA1 DHRS2 CSMD1

8.60e-0819012984971857eac9af17d66d673ed2ab7072639f60a10
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 ANK3 CDHR3 AOX1 PTPRD SLC5A12 CDH6 CDH9

8.95e-0819112983c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 ANK3 CDHR3 AOX1 PTPRD SLC5A12 CDH6 CDH9

8.95e-0819112981c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

COL12A1 AOX1 CDH19 EBF2 TGFBR3 DIAPH2 ZFHX3 FYN

9.32e-081921298356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MXRA5 ZEB1 COL12A1 NRCAM CDH19 EBF2 FAT1 CDH6

1.01e-0719412982d66091097e106c7bee22e5281f50724700bdf8d
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

ZEB1 COL12A1 AOX1 CDH19 EBF2 TGFBR3 ZFHX3 FYN

1.05e-071951298a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

ZEB1 CDH19 EBF2 TGFBR3 PTPRD DIAPH2 ZFHX3 FYN

1.05e-071951298ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MXRA5 COL12A1 RFTN2 LEPR TGFBR3 DLC1 PLPP3 GREB1

1.23e-0719912986200618e029063486719479c41eaf31798bd13cf
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZEB1 COL12A1 AOX1 LEPR EBF2 TGFBR3 DLC1 FYN

1.28e-0720012980c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CSMD3 EYS PTPRD CPNE4 TNR CDH6 CDH9

1.68e-071391297a1945b07f177cde40e7eea03a19236ce76165857
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TANC2 NRCAM RHO BMX DIAPH2 ZFHX3 CSMD1

6.09e-0716812978072d0496b7b730c4601009eaa69ec5366d26d73
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 PTPRD EHHADH SLC5A12 CDH6 CDH9

6.09e-071681297fa0d251693935116adf633d02b7ec4a295100865
ToppCellP07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NID2 CADM4 L1CAM NEB CDH19 CELA1 CPNE4

7.13e-0717212978d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 AOX1 LEPR EBF2 TGFBR3 PLPP3 GREB1

7.13e-071721297e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 AOX1 PTPRD SLC5A12 CSMD1 CDH9

8.32e-0717612971595dbeee336a81e581325d63208ec6262664ee9
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC5A10 CDHR3 AOX1 EHHADH SLC5A12 CDH6 CDH9

8.97e-07178129723a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TANC2 ANK3 NSD2 ADGRV1 SH3PXD2A SCNN1A MUC5AC

9.32e-0717912976e965e424eebef50f0202cff75f458be395cfca1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 AOX1 SLC5A12 CPNE4 CDH6 CDH9

9.32e-071791297d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCellP28-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ANK3 CADM4 L1CAM CDH19 ZFYVE28 GREB1 CSMD1

9.67e-0718012971e819c5c87704ec6535dfeaae56561895e239d07
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CDHR3 AOX1 FAT1 PTPRD SLC5A12 CDH6 CDH9

9.67e-071801297358923e4228035a3e90e2957392089219e90dcd7
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 ANK3 CADM4 L1CAM CDH19 GREB1 CSMD1

9.67e-071801297d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 ANK3 CADM4 L1CAM CDH19 GREB1 CSMD1

9.67e-071801297dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCellRA-16._Neuronal|RA / Chamber and Cluster_Paper

OGFRL1 ANK3 CADM4 L1CAM CDH19 IFNGR2 DLC1

9.67e-0718012975842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

AOX1 CDH19 CFHR3 DIAPH2 ZFHX3 GNAO1 FYN

1.00e-0618112972b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 CADM4 L1CAM CDH19 OTOP1 DHRS2 CSMD1

1.04e-061821297d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 ANK3 CADM4 L1CAM CDH19 GREB1 CSMD1

1.04e-061821297812ff2a50a510b18d865e89465dba1754a08ef61
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 CADM4 L1CAM CDH19 OTOP1 DHRS2 CSMD1

1.04e-061821297e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 CADM4 L1CAM CDH19 OTOP1 DHRS2 CSMD1

1.04e-06182129782ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

NRCAM CDHR3 AOX1 FAT1 PTPRD CDH6 CDH9

1.12e-06184129751ed1ebfdef45149541917c66cbacad87072e51f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 AOX1 EHHADH SLC5A12 CPNE4 CDH9

1.12e-0618412979434731f651820b05335085582960f08fbf895de
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 CADM4 L1CAM CSMD3 CELA1 DHRS2 CSMD1

1.12e-061841297a7399a72f065d68800e3e0b2031d9894e0cc0ba4
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 CADM4 L1CAM CDH19 CSMD3 DHRS2 CSMD1

1.20e-061861297d8d559daff4aeef334d403fde4e3ee2e4a6086d0
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADGRV1 CSMD3 DIAPH2 IFI30 ZFHX3 CSMD1 USH2A

1.20e-06186129723b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 PTPRD EHHADH SLC5A12 CDH6 CDH9

1.25e-0618712971b82920588f9e26ef1db244d452736d75fcfd342
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NID2 ANK3 CADM4 L1CAM CDH19 DHRS2 CSMD1

1.25e-0618712978e8b147258982b359447add5027318f5b6d51963
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

CDHR3 AOX1 FAT1 PTPRD EHHADH SLC5A12 CDH6

1.25e-061871297d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

CDHR3 AOX1 PTPRD EHHADH SLC5A12 CDH6 CDH9

1.25e-061871297738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 PTPRD EHHADH SLC5A12 CDH6 CDH9

1.25e-061871297c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZEB1 COL12A1 NRCAM B3GALT5 FAT1 GREB1 GNAO1

1.25e-061871297c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 PTPRD EHHADH SLC5A12 CDH6 CDH9

1.29e-061881297f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 PTPRD EHHADH SLC5A12 CDH6 CDH9

1.29e-0618812970792432cd4c564dea1102241ea9884f7ced7658c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 PTPRD EHHADH SLC5A12 CDH6 CDH9

1.34e-061891297204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZEB1 RALGAPA2 POF1B LEPR MMRN1 BMX CSMD1

1.34e-0618912977346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 CDHR3 PTPRD EHHADH SLC5A12 CDH6 CDH9

1.34e-06189129713fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CDHR3 ZNF365 FAT1 PTPRD SLC5A12 CDH6 CDH9

1.34e-06189129728b502611829e4a24caff2562545c7db97686099
ToppCelldroplet-Heart-nan-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 NRCAM CADM4 L1CAM ZFYVE28 EHHADH CSMD1

1.34e-0618912970493f7b79127c207fd7ade778ef4810500495d7e
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NID2 NRCAM CDH19 EBF2 FAT1 DLC1 CDH6

1.39e-0619012974eb92aef1ee868f4537483d19014d947b7684612
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

ZEB1 COL12A1 CDH19 EBF2 TGFBR3 PTPRD ZFHX3

1.39e-06190129712992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NID2 NRCAM CDH19 EBF2 FAT1 DLC1 CDH6

1.39e-0619012977be4341e2909101d756f14031c21e705eb45e69a
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 ANK3 PERP FAT1 VILL SCNN1A GREB1

1.44e-061911297b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZEB1 COL12A1 NRCAM B3GALT5 FAT1 GREB1 GNAO1

1.49e-06192129772881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 AOX1 EHHADH GREB1 SLC5A12 CSMD1 CDH9

1.49e-0619212973e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

NID2 COL12A1 CDH19 TGFBR3 DLC1 SH3PXD2A CDH6

1.54e-061931297e1de67ddada87229f5db0ec193a6da8745a86a64
ToppCellLA-14._Fibroblast_III|LA / Chamber and Cluster_Paper

AOX1 CDH19 EBF2 TGFBR3 PLPP3 SH3PXD2A ZFHX3

1.54e-0619312977426c291bac59e539c427bcaae18abc7d397d44e
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal-choroid_plexus/mesenchymal-like_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

NID2 COL12A1 CDH19 TGFBR3 DLC1 SH3PXD2A CDH6

1.54e-061931297b6f5a85210e60798205eaf5884cdb540f549d08a
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

COL12A1 AOX1 CDH19 EBF2 TGFBR3 ZFHX3 FYN

1.54e-061931297dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

ZEB1 CDH19 EBF2 TGFBR3 DIAPH2 ZFHX3 FYN

1.59e-06194129711c79a8c56ece42713b04b321982e41e239f07a5
ToppCellRA|World / Chamber and Cluster_Paper

NMNAT2 PHF20 CDH19 FAT1 GNAO1 SLC5A12 FYN

1.59e-06194129708f0afbb68a63150fbe107a5337299081c3f69e4
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TANC2 ACACA ANK3 ADGRV1 DLC1 PTPRD SCNN1A

1.59e-06194129797534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

ZEB1 AOX1 CDH19 EBF2 TGFBR3 ZFHX3 FYN

1.59e-061941297234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

AOX1 CDH19 EBF2 TGFBR3 DIAPH2 ZFHX3 FYN

1.65e-0619512976a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NID2 COL12A1 AOX1 EBF2 TGFBR3 PTPRD PLPP3

1.77e-0619712973bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NID2 COL12A1 AOX1 EBF2 TGFBR3 PTPRD PLPP3

1.77e-06197129717344464fdcc5ba0c03959696b97c195f11e644c
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NID2 COL12A1 AOX1 EBF2 TGFBR3 PTPRD PLPP3

1.77e-0619712975b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM4 L1CAM RFTN2 ADGRV1 CDH19 TSHZ1 CDH6

1.83e-061981297c506334d81af672ef9ddc8c4fd2a790bdb58e63e
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM4 L1CAM RFTN2 ADGRV1 CDH19 TSHZ1 CDH6

1.89e-061991297ce699726ac4825c65bf934cb9a76202ad7340596
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM4 L1CAM RFTN2 ADGRV1 CDH19 TSHZ1 CDH6

1.89e-061991297f1d5808ccb1d5d4e2d34f864e705e2484000e88f
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NID2 MXRA5 ITSN1 AOX1 PTPRD PLPP3 SH3PXD2A

1.89e-0619912978b86c69aaf60feff53aa782559cfece7342a23de
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal|GW09 / Sample Type, Dataset, Time_group, and Cell type.

NMNAT2 ANK3 NRCAM L1CAM PTPRD GNAO1 CPNE4

1.95e-062001297e9eb348a66011d8aace4331f84690ae27cb0d061
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ZEB1 COL12A1 RALGAPA2 LEPR DLC1 DIAPH2 FYN

1.95e-062001297dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

CSMD3 EYS CPNE4 CSMD1 TNR USH2A

4.31e-061461296c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NEK10 CDHR3 ADGRV1 EYS CPNE4 TNR

6.09e-061551296498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

RFTN2 RABGAP1 ADGRV1 PTPRD GNAO1 TNR

7.57e-061611296347edb0de10850b7d16c40945751033289289c9b
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANK3 CADM4 L1CAM CDH19 DHRS2 CSMD1

8.41e-0616412963caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCellsevere_influenza-CD4+_CTL|World / disease group, cell group and cell class (v2)

IL12RB1 PERP ZNF365 ZFYVE28 TGFBR3 DHRS2

9.01e-061661296cdc3e200373718f26fe02ee516928097103f46e2
Drug5186324; Up 200; 2uM; MCF7; HT_HG-U133A_EA

RABGAP1 NEB ZNF365 ARHGAP5 EHHADH ZNF350 C5 GREB1 DHRS2 MUC5AC

1.48e-0719512710900_UP
DrugSTOCK1N-35874; Up 200; 14uM; PC3; HT_HG-U133A

NID2 ITSN1 SRC CPD NEB DLC1 CLN3 IKBKB

1.41e-0519512786583_UP
DrugOleandomycin phosphate [7060-74-4]; Down 200; 5uM; MCF7; HT_HG-U133A

ITFG2 NEB IFNGR2 TGFBR3 PIK3R2 GREB1 CDH6 SNX1

1.46e-0519612785676_DN
DrugIsocorydine (+) [475-67-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A

ITFG2 AOX1 CPD NEB RNASEL PLPP3 ANKRD12 SNX1

1.46e-0519612782780_DN
DrugDNA-PK Inhibitor III; Down 200; 1uM; MCF7; HT_HG-U133A

ITFG2 LEPR TGFBR3 RNASEL EHHADH ZNF350 FYN ARHGEF6

1.52e-0519712787543_DN
DrugRetinoic acid [302-79-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A

ITFG2 NEB PLPP3 DIAPH2 ZFHX3 ZNF350 GREB1 MUC5AC

1.52e-0519712783165_DN
Drug2-propylpentanoic acid; Down 200; 500uM; PC3; HT_HG-U133A

CLTCL1 PHF20 ANK3 NRCAM ITFG2 SRC NEB CDH6

1.57e-0519812784464_DN
DrugTrimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A

IL12RB1 PHF20 ITFG2 NEB DLC1 SCNN1A ZNF350 DHRS2

1.57e-0519812787235_UP
DrugMerbromin [129-16-8]; Up 200; 5uM; MCF7; HT_HG-U133A

ITFG2 AOX1 PLPP3 DIAPH2 GREB1 DHRS2 IKBKB CDH6

1.57e-0519812783439_UP
DrugEthambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A

VWA8 ITSN1 SRC RABGAP1 B4GALT5 DIAPH2 FYN SNX1

1.57e-0519812781481_DN
DrugBadg

CLTCL1 CLTC

3.09e-0521272CID000125951
Diseasesevere acute respiratory syndrome, COVID-19

MXRA5 DCAF8L2 B4GALT5 ZFYVE28 TGFBR3 EYS PTPRD DIAPH2 ZFHX3 CSMD1 TNR

3.63e-0644712611EFO_0000694, MONDO_0100096
DiseaseAnti-herpes simplex virus 2 IgG measurement

ADAM32 TAMM41

1.81e-0521262EFO_0009350
Diseaseuterine fibroid

ZEB1 NEK10 EBF2 ANKRD12 GREB1 CSMD1 FYN

2.45e-051991267EFO_0000731
DiseaseRetinitis Pigmentosa

ARL2BP RHO EYS CLN3 USH2A

8.60e-051041265C0035334
Diseaseasthma, response to diisocyanate

COL12A1 PTPRD SH3PXD2A GREB1 SLC5A12 CSMD1 OTOG

1.35e-042611267EFO_0006995, MONDO_0004979
Diseasemucinous adenocarcinoma (is_marker_for)

ZFHX3 MUC5AC

1.79e-0451262DOID:3030 (is_marker_for)
Diseaseretinitis pigmentosa (implicated_via_orthology)

RHO EYS USH2A

2.06e-04271263DOID:10584 (implicated_via_orthology)
DiseaseColorectal Carcinoma

ACACA NRCAM SRC TSPEAR CSMD3 HPS3 FAT1 DLC1 PTPRD DHRS2 ZNF292

2.19e-0470212611C0009402
Diseasecolorectal health

ARMC3 VWA8 ADGRV1 EYS ZFHX3 CSMD1

2.32e-042011266EFO_0008460
Diseaselate-onset Alzheimers disease

ANK3 NEK10 AOX1 NHLRC3 CDH19 USP10 DLC1

2.68e-042921267EFO_1001870
Diseasedry eye syndrome (implicated_via_orthology)

AWAT2 MUC5AC

2.68e-0461262DOID:10140 (implicated_via_orthology)
DiseasePremature ovarian failure

POF1B DIAPH2

3.75e-0471262cv:C0085215
DiseaseMASA syndrome (implicated_via_orthology)

NRCAM L1CAM

3.75e-0471262DOID:0060246 (implicated_via_orthology)
Diseasetelomere length

TSPEAR SH3PXD2A CSMD1 ATP1A4 FYN TNR CDH9

4.07e-043131267EFO_0004505
Diseasechronotype measurement

TANC2 NMNAT2 ANK3 SLC36A4 VWA8 RFTN2 CDH19 RNASEL PTPRD TSHZ1 GNAO1 CSMD1

4.07e-0488212612EFO_0008328
Diseaseemphysema imaging measurement

NSD2 DLC1 ANKRD12 GNAO1 CSMD1

4.18e-041461265EFO_0007626
Diseaseglucagon-like peptide-1 measurement

COL12A1 CSMD1

7.96e-04101262EFO_0008465
Diseasedisease progression measurement, Crohn's disease

CDHR3 PTPRD CSMD1

1.07e-03471263EFO_0000384, EFO_0008336
DiseaseColorectal Neoplasms

NRCAM SRC FAT1 DLC1 PTPRD ZNF292

1.25e-032771266C0009404
DiseaseDrug habituation

NRCAM CSMD3 EHHADH CSMD1

1.52e-031151264C0013170
DiseaseDrug abuse

NRCAM CSMD3 EHHADH CSMD1

1.52e-031151264C0013146
DiseasePrescription Drug Abuse

NRCAM CSMD3 EHHADH CSMD1

1.52e-031151264C4316881
DiseaseSubstance-Related Disorders

NRCAM CSMD3 EHHADH CSMD1

1.52e-031151264C0236969
DiseaseDrug Use Disorders

NRCAM CSMD3 EHHADH CSMD1

1.52e-031151264C0013222
DiseaseDrug Dependence

NRCAM CSMD3 EHHADH CSMD1

1.52e-031151264C1510472
DiseaseSubstance Dependence

NRCAM CSMD3 EHHADH CSMD1

1.52e-031151264C0038580
DiseaseSubstance Use Disorders

NRCAM CSMD3 EHHADH CSMD1

1.52e-031151264C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

NRCAM CSMD3 EHHADH CSMD1

1.52e-031151264C0029231
DiseaseSubstance abuse problem

NRCAM CSMD3 EHHADH CSMD1

1.57e-031161264C0740858
DiseaseMetastatic melanoma

NEK10 MAP3K15 FYN

1.61e-03541263C0278883
Diseaseprostate cancer (is_implicated_in)

SRC RNASEL ZFHX3 IKBKB

1.62e-031171264DOID:10283 (is_implicated_in)
Diseasethird ventricle volume measurement

ANK3 PTPRD

1.83e-03151262EFO_0010335
Diseaseurate measurement, spine bone mineral density

SRC PTPRD CPNE4

1.98e-03581263EFO_0004531, EFO_0007701
Diseaseresponse to triptolide, cytotoxicity measurement

NEK10 CSMD1

2.09e-03161262EFO_0006952, EFO_0007662
Diseasecathepsin L1 measurement

PIK3R2 IFI30

2.09e-03161262EFO_0010619
Diseasemelanoma

COL12A1 ADGRV1 EYS FYN

2.12e-031261264EFO_0000756
DiseaseDisorder of eye

ADGRV1 RHO EYS CLN3 USH2A

2.21e-032121265C0015397
DiseaseAstrocytosis

LEPR TNR

2.36e-03171262C3887640
DiseaseAntibody Deficiency Syndrome

LEPR C5

2.36e-03171262C0003257
DiseaseGliosis

LEPR TNR

2.36e-03171262C0017639
Diseasealcohol consumption measurement

EEF1AKMT4-ECE2 COL12A1 ACACA DNAJC30 ADGRV1 CSMD3 B4GALT5 DMAP1 MMRN1 CLN3 ZFHX3 CPNE4 CSMD1

2.56e-03124212613EFO_0007878
Diseasebitter alcoholic beverage consumption measurement

MMRN1 PTPRD ZFHX3 CSMD1

2.58e-031331264EFO_0010092
Diseaseandrostenedione measurement, estrone measurement

ARMC3 PTPRD

2.65e-03181262EFO_0007970, EFO_0007972
Diseaselanguage measurement

ANK3 DCAF8L2 SLC25A25 FYN

2.65e-031341264EFO_0007797
Diseaseneuroticism measurement, cognitive function measurement

NMNAT2 CDH19 KIAA0825 ZFHX3 GNAO1 CSMD1 TNR CDH9

3.04e-035661268EFO_0007660, EFO_0008354
Diseaseserum alanine aminotransferase measurement, response to combination chemotherapy

PERP GREB1 CPNE4

3.52e-03711263EFO_0004735, EFO_0007965
Diseasehaptoglobin measurement

DLC1 ZFHX3

3.60e-03211262EFO_0004640
DiseaseAlzheimer disease, age at onset

COL12A1 SZT2 CDH19 CSMD3 FAT1 USH2A

3.62e-033431266EFO_0004847, MONDO_0004975
DiseaseRetinitis pigmentosa

RHO EYS USH2A

3.95e-03741263cv:C0035334
Diseasemultiple sclerosis

VWA8 CDHR3 IFNGR2 TGFBR3 RNASEL IFI30 ZFHX3 CSMD1

4.06e-035941268MONDO_0005301

Protein segments in the cluster

PeptideGeneStartEntry
AQYVLEVQKVTLYPA

URB2

1451

Q14146
TIYVVTPTYARLVQK

B3GAT3

76

O94766
PLTKNYYTVVLQNIL

ARHGEF6

236

Q15052
IKVEPNYNITIFVDT

CSMD1

2351

Q96PZ7
IYINFTVLQTEPIYD

CSMD3

2321

Q7Z407
QTPVERQYPFQIVYK

BMX

71

P51813
TSKAVPIYVINDIYP

ADGRV1

2181

Q8WXG9
YVRLIDSVTKQPIAY

EBF2

126

Q9HAK2
YVLKVTRQSPNSYVV

ACACA

681

Q13085
ASQVYNVSKSVPYIK

B3GALT5

226

Q9Y2C3
SSEIEYEQISYIIPI

ADAM32

41

Q8TC27
YVYEVTKSILPITNI

ARMC3

726

Q5W041
IYTPIFNEYISLVEK

ARL2BP

61

Q9Y2Y0
KSISIYEIQEFYVPL

ANKRD12

2036

Q6UB98
IRPQYYKIIEECVSQ

DIAPH2

441

O60879
TYDALYKNITVNLTP

B4GALT5

366

O43286
VYVSTQFPKYIQDIV

AOX1

771

Q06278
INSILDIVTKVENYY

RFTN2

56

Q52LD8
YYTLKPEVNNESFVI

RHO

191

P08100
PVKSPREYYVQQEVI

ZFYVE28

181

Q9HCC9
PQTNTEIANYPIYKI

RABGAP1

201

Q9Y3P9
FVNLPYYAVVKVDTE

FAT1

2081

Q14517
TIPNIKQSALEYFVY

OGFRL1

271

Q5TC84
SSVIAVYLQPKNPYA

OR2H2

251

O95918
VQEYPTLKVPYETLN

MAEA

16

Q7L5Y9
QIYPDVTLKTYSEIT

EYS

1751

Q5T1H1
FLYPESEVIIKYQNI

KIAA0825

201

Q8IV33
TVYYLVQLAADQVPL

GREB1

441

Q4ZG55
PELLEQQKYTVTVDY

IKBKB

191

O14920
ILTEYTLKYQPINST

NRCAM

981

Q92823
ESKVTQTLIPYYISV

MMRN1

866

Q13201
KVGLYTITVNPANTY

DCAF8L2

366

P0C7V8
AVQAAVQYPYEVGIK

EHHADH

236

Q08426
TIIKEQLYHPNIVRY

NEK10

576

Q6ZWH5
NPVIYSIKTKQIQYG

OR51B2

286

Q9Y5P1
FYTVITAILNPVIYS

OR4X2

266

Q8NGF9
FQIISLVIYPVKYTQ

PERP

121

Q96FX8
VNKPYGKVQIYTADI

NSD2

996

O96028
PLQYQVKYSENSTTV

LEPR

266

P48357
NAYIYVVQLPAKILT

L1CAM

416

P32004
DNCTYVLVQQIVPVY

MUC5AC

4941

P98088
TEQYVSVQKIVVHPY

CELA1

86

Q9UNI1
KPVYITTTRDNENIY

RALGAPA2

276

Q2PPJ7
YPQTTIRKYVVQNPE

POF1B

131

Q8WVV4
SPCLVYVTFNQKIYV

ITFG2

366

Q969R8
YLSIKTNIQGQVPYV

NID2

641

Q14112
LLYPVSKYQQDQIVK

PIK3R2

421

O00459
LFAKSNTVYNPVIYV

OPN3

296

Q9H1Y3
LPYSILAIVEKYIQN

OTOP1

426

Q7RTM1
QTVNAYYLPTKNEIV

EEF1AKMT4-ECE2

676

P0DPD8
LKVYVPQSRVEYQCQ

CFHR3

226

Q02985
TVIAVNLYLVVFTPY

AWAT2

31

Q6E213
QPQTTYDITVLPIYK

COL12A1

1056

Q99715
KSNAPLVNVTLYYEA

IFI30

56

P13284
YIPPYNATVVQKLLD

QRSL1

96

Q9H0R6
KTVQVPVYSEQEYQL

DMAP1

131

Q9NPF5
QQYFAAKDTVYAVIP

ATPAF1

166

Q5TC12
KYTVIIQVQDVAPPY

CDHR3

426

Q6ZTQ4
LVQLYAVVSEEPIYI

FYN

326

P06241
QNPVSYVYLEVVSKH

C5

96

P01031
KSVLAEVPNQVVDYY

CPNE4

521

Q96A23
PLTISAQENVKVVYY

ITSN1

731

Q15811
LVTYPYDKPVQTVEN

CPD

1101

O75976
SKQTQYVLDVQYSPT

CADM4

211

Q8NFZ8
TLPVYVSFVQVGKQY

ANK3

3091

Q12955
SPEVTLQLYNSVKYE

IL12RB1

126

P42701
NSTRPVVYQVQFKYT

IFNGR2

56

P38484
KVVYSILQGQPYFSV

CDH6

196

P55285
VPSTATQAQIKAAYY

DNAJC30

56

Q96LL9
LLVDYYVKIQDTNVT

HAUS4

91

Q9H6D7
YNPVVALGVYNVSKT

DHRS2

176

Q13268
VPVENLYPSKYTQQV

SCNN1A

401

P37088
KVVYSILQGQPYFSV

CDH9

196

Q9ULB4
YNIEQISSIPLYVQV

CDH19

446

Q9H159
VPANENIKGYYIIIV

PTPRD

1131

P23468
DTKYVQQPCVALTVY

OTOG

2336

Q6ZRI0
AYYPAVEQKLVVETR

PHF20

846

Q9BVI0
SSVIAVYLQPKNPYA

OR2H1

251

Q9GZK4
VLVIEPTKVYQPSYV

MAP3K15

531

Q6ZN16
QPEIYVTIQAYSSII

SZT2

146

Q5T011
VYQVTYQLKIPCTAL

SLC35A1

116

P78382
PNGVVTEYSIYVNNK

USH2A

3046

O75445
VQLYAVVSEEPIYIV

SRC

326

P12931
AVIAKENYPLYIRST

TRAPPC2L

6

Q9UL33
NVTPQPYLKNSVVAY

TADA1

211

Q96BN2
VYQYPEKSQQAVLTP

HPS3

366

Q969F9
STIQNPYVAALYKQV

PLPP3

116

O14495
PVVQIIYSDKFRDVY

FNTA

86

P49354
VKQYKPVVYSNTIQS

GNAO1

66

P09471
FPDLVIYVYTKLQNT

RNASEL

696

Q05823
YKVVPVSLSEVYLLQ

TANC2

676

Q9HCD6
IPYLDAYKTQRQLVV

ARHGAP5

256

Q13017
FIYVTPSQKEYLEIN

OR6J1

256

Q8NGC5
LSETFLQIYQYVPKD

DLC1

1166

Q96QB1
VAYSIQIYFNEEPTK

ATP1A4

121

Q13733
VPLVVVYFAEYFINQ

CLN3

286

Q13286
LQKYIEIYVQKVNPS

CLTC

796

Q00610
LQRYIEIYVQKVNPS

CLTCL1

796

P53675
VIPAVSISYVVYENL

SLC25A25

446

Q6KCM7
IYAAQAYAVPNVEKT

SLC35A4

76

L0R6Q1
VVKQKPSYVNLYSIS

ZNF365

91

Q70YC5
QALEAQYKYIVIEPT

TMEM11

51

P17152
IYTFNQVKPQTIPYT

TRPM6

1841

Q9BX84
QVQKYVPLNSYVPSF

NHLRC3

331

Q5JS37
AYVAYKVTTQTSLPL

SNX1

161

Q13596
IYISSEIVTLPEYIQ

SLC5A10

111

A0PJK1
YVTVQPYTSQSKDEI

SH3PXD2A

271

Q5TCZ1
VNVAPSVINYILYLT

ZNF577

466

Q9BSK1
IGIPLTYSQYKQLTI

VPS16

436

Q9H269
VQEYKVVYSTLAGEQ

TNR

621

Q92752
EVYTVAIQSYVKARP

ZNF292

76

O60281
YGSILQENPQVVYKS

TAMM41

216

Q96BW9
FIQAKGYPTYTNVEV

VILL

316

O15195
ANKQTILIPQVAYTY

ZEB1

831

P37275
VVPSVINYVLFYVTE

ZNF350

516

Q9GZX5
EYVVYDLKTQVPPQQ

ZACN

201

Q401N2
PIVKYSVQVSDSAVY

TRAV40

86

A0A0B4J280
YQVVKPTAERTAYLL

USP10

776

Q14694
VIKNVYYPQVSFGIS

VN1R17P

11

Q8TDU5
NEVLKYPYETNIRVT

TSPEAR

256

Q8WU66
KPVRYAATVIYIVQT

SLC5A12

121

Q1EHB4
INYPYSTREVVNIVK

VWA8

971

A3KMH1
VTYSIQFYVPAEIII

SLC36A4

361

Q6YBV0
VSYPQDSLAQIKAVY

TSHZ1

106

Q6ZSZ6
GVVYYNSIVIQVPAL

TGFBR3

516

Q03167
YLPVLQDASYVVSVI

UBE3C

181

Q15386
TTITPEQLEILYQKY

ZFHX3

2646

Q15911
ATIRNKTYLAVQVPY

MXRA5

2346

Q9NR99
TRNDYKLVTDTPVYV

NEB

4886

P20929
PVIDYILKSQLYINA

NMNAT2

291

Q9BZQ4