Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

GLI2 HDAC1 PRDM1

1.32e-0483243GO:1990841
GeneOntologyMolecularFunctiontranscription coregulator activity

BCLAF3 MED12L ARID1B CBX4 HDAC1

4.73e-04562245GO:0003712
GeneOntologyCellularComponentmediator complex

BCLAF3 MED12L

8.21e-0437242GO:0016592
GeneOntologyCellularComponentPcG protein complex

UBAP2L CBX4

1.62e-0352242GO:0031519
PathwayREACTOME_STAT3_NUCLEAR_EVENTS_DOWNSTREAM_OF_ALK_SIGNALING

HDAC1 PRDM1

1.04e-0411202M42523
PathwayBIOCARTA_PRC2_PATHWAY

CBX4 HDAC1

1.72e-0414202M22025
PathwayWP_TRANSCRIPTION_COFACTORS_SKI_AND_SKIL_PROTEIN_PARTNERS

HDAC1 MERTK

2.89e-0418202M39825
Pubmed

CBX4 transcriptionally suppresses KLF6 via interaction with HDAC1 to exert oncogenic activities in clear cell renal cell carcinoma.

CBX4 HDAC1

1.37e-06324232113161
Pubmed

The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway.

GLI2 HDAC1

2.74e-06424231558698
Pubmed

Alternative splicing regulates Prdm1/Blimp-1 DNA binding activities and corepressor interactions.

HDAC1 PRDM1

4.56e-06524222733990
Pubmed

Involvement of histone demethylase LSD1 in Blimp-1-mediated gene repression during plasma cell differentiation.

HDAC1 PRDM1

4.56e-06524219124609
Pubmed

MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein.

CBX4 HDAC1

6.83e-06624212829790
Pubmed

CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes.

DOCK3 HDAC1

9.56e-06724221931736
Pubmed

Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3.

GLI2 HDAC1

9.56e-06724212435627
Pubmed

Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation.

GLI2 HDAC1

1.64e-05924220081843
Pubmed

PKA-mediated Gli2 and Gli3 phosphorylation is inhibited by Hedgehog signaling in cilia and reduced in Talpid3 mutant.

GLI2 KIAA0586

2.50e-051124228673820
Pubmed

HSP70-Hrd1 axis precludes the oncorepressor potential of N-terminal misfolded Blimp-1s in lymphoma cells.

CBX4 PRDM1

2.50e-051124228842558
Pubmed

BMI1-UBR5 axis regulates transcriptional repression at damaged chromatin.

UBAP2L CBX4

3.54e-051324227647897
Pubmed

Transcriptional map of chromosome region 6q16-->q21.

REV3L PRDM1

4.13e-051424210575223
Pubmed

Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control.

ARID1B HDAC1

4.77e-051524217255939
Pubmed

Coordinated histone modifications mediated by a CtBP co-repressor complex.

CBX4 HDAC1

4.77e-051524212700765
Pubmed

The REV7 subunit of DNA polymerase ζ is essential for primordial germ cell maintenance in the mouse.

REV3L PRDM1

5.44e-051624223463509
Pubmed

Transcription Factor hDREF Is a Novel SUMO E3 Ligase of Mi2α.

CBX4 HDAC1

5.44e-051624227068747
Pubmed

Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development.

GLI2 PRDM1

7.75e-051924237516749
Pubmed

Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development.

GLI2 HDAC1

1.14e-042324221937600
Pubmed

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.

ARID1B HDAC1

1.47e-042624210778858
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

ARID1B CBX4 HDAC1

1.70e-0415724330186101
Pubmed

REST repression of neuronal genes requires components of the hSWI.SNF complex.

ARID1B HDAC1

1.71e-042824212192000
Pubmed

RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.

UBAP2L ARID1B

1.83e-042924236800290
Pubmed

The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor.

ARID1B CBX4

2.38e-043324219336002
Pubmed

Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation.

ARID1B HDAC1

2.99e-043724224335282
Pubmed

Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation.

GLI2 CBX4

3.50e-044024228805822
Pubmed

Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.

ARID1B HDAC1

3.50e-044024234585037
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

UBAP2L GLI2 HDAC1

3.62e-0420324322083510
Pubmed

PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes.

CBX4 HDAC1

3.68e-044124222325352
Pubmed

EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.

UBAP2L CBX4

4.24e-044424227505670
Pubmed

Opposing LSD1 complexes function in developmental gene activation and repression programmes.

CBX4 HDAC1

4.64e-044624217392792
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

THSD4 CHSY1 ENPP5 LRRTM4 PAN3

4.90e-0498524512975309
Pubmed

SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.

UBAP2L CBX4 HDAC1

6.26e-0424524335652658
Pubmed

Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior.

ARID1B HDAC1

6.87e-045624229184203
InteractionBCOR interactions

UBAP2L CBX4 HDAC1 NFS1 PRDM1

2.46e-05302245int:BCOR
InteractionKDM2B interactions

GLI2 CBX4 HDAC1 PRDM1

3.68e-05161244int:KDM2B
InteractionARID3C interactions

OR2T1 CBX4

6.08e-0510242int:ARID3C
Cytoband6q21

REV3L PRDM1

1.16e-03962426q21
CytobandEnsembl 112 genes in cytogenetic band chr6q21

REV3L PRDM1

1.83e-03121242chr6q21
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK3 NOX4 GLI2 LRRTM4

2.31e-06177244b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 DOCK3 GLI2 LRRTM4

2.64e-061832447eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 DOCK3 GLI2 LRRTM4

2.76e-061852446712512100ccef456d2e2bd201d0987986c92ac9
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 DOCK3 GLI2 LRRTM4

3.13e-0619124414057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

THSD4 COL8A1 GLI2 REV3L

3.68e-061992449503646ff1ad248181146ce767e9d12e882ec3bd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

8.30e-051592432607b562903228274fbd96168ba826782fab0b53
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

8.30e-05159243e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK3 NOX4 LRRTM4

9.10e-05164243e3983f655cdba308fb192182829f17bef99ce0ba
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

THSD4 DOCK3 MERTK

1.01e-041702434232fe937909f93d3736988c707b8f95ce993398
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 ENPP5 KIAA0586

1.05e-04172243f814b6134ad608015765399d54cc1e5e1873ed34
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RHBDL1 HDAC1 PRDM1

1.10e-0417524316c835e62a3321f6cf6163954889946bbb869498
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.12e-041762439bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.12e-041762433f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL8A1 LRRTM4 REV3L

1.14e-041772439ec7f1e64312d26d434b3312b58386715dbad644
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL8A1 LRRTM4 REV3L

1.14e-04177243016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 GLI2 LRRTM4

1.18e-0417924302c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THSD4 DOCK3 COL8A1

1.22e-04181243d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.28e-04184243c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 DOCK3 LRRTM4

1.30e-041852433b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 MERTK

1.34e-041872437ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

NOX4 COL8A1 GLI2

1.34e-041872434ea486991f66c29728d127171a07b81404ec0b78
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

THSD4 GLI2 REV3L

1.34e-0418724376bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THSD4 DOCK3 GLI2

1.36e-041882434d1e5f85342ae550086609d7680e32730b78b5d2
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 DOCK3 GLI2

1.38e-0418924345e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.41e-0419024370c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 GLI2 LRRTM4

1.41e-041902431f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 GLI2 LRRTM4

1.41e-041902432306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.43e-0419124339092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.43e-04191243107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellfacs-MAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP5 COL8A1 GLI2

1.43e-04191243b4fba92f9bd1354a07fedfca7304a3757e6d5beb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.43e-04191243bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 DOCK3 GLI2

1.43e-04191243b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.43e-04191243ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.45e-041922435105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.45e-04192243d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NOX4 COL8A1 GLI2

1.45e-0419224367e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

NOX4 ARID1B PAN3

1.45e-04192243e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellASK454-Immune-T_cell|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

ABCD2 HDAC1 PRDM1

1.47e-0419324327c38a364bcdb4c0967155f18aa81d37e17c920b
ToppCellLA|World / Chamber and Cluster_Paper

NOX4 COL8A1 GLI2

1.47e-04193243d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THSD4 ARID1B PAN3

1.47e-04193243779276e775cb2492e8dd36436295a536084a6415
ToppCellASK454-Immune-T_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

ABCD2 HDAC1 PRDM1

1.47e-0419324311e1db416dc9a0b99ddb72d6021fba6e25405b5c
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

NOX4 COL8A1 LRRTM4

1.47e-04193243e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

NOX4 COL8A1 GLI2

1.49e-04194243d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.52e-04195243dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.52e-0419524349c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

NOX4 ARID1B REV3L

1.52e-041952436a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD4 MERTK PRDM1

1.52e-041952437e0ef92059ff34e368d2324815f49b50e3ca7332
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 ARID1B PAN3

1.54e-04196243ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NOX4 COL8A1 GLI2

1.54e-04196243525d6c8a277364e624e7cc586275f8a891436b57
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.54e-04196243802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.54e-041962433a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.54e-04196243bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 GLI2 REV3L

1.54e-041962432b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.54e-04196243fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellmetastatic_Lymph_Node-Fibroblasts|metastatic_Lymph_Node / Location, Cell class and cell subclass

NOX4 COL8A1 GLI2

1.54e-04196243275e153347caf94edc0c50021bbab49c8696fecb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.56e-04197243ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 COL8A1 GLI2

1.56e-0419724337f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 ARID1B PAN3

1.59e-041982431996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 ARID1B PAN3

1.61e-0419924394b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 CHSY1 COL8A1

1.61e-041992436a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCellTracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK3 COL8A1 LRRTM4

1.61e-04199243e9009eee7f77b9c9917f8e0e723001d9e76eb553
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Astrocyte|GW12 / Sample Type, Dataset, Time_group, and Cell type.

THSD4 GLI2 CBX4

1.63e-04200243b9bd6c4381c92bfc1bfff9aa778a62a41d08f1ef
ToppCellMonocytes-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CHSY1 PRDM1

9.48e-0485242e73603d6f22bb56159aa5d1a2695775f038e61d8
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)|Hippocampus / BrainAtlas - Mouse McCarroll V32

NOX4 PRDM1

1.08e-039124278e2e65beb15bf1e251974c72fbcfab817492772
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

NOX4 PRDM1

1.08e-0391242f59908093416ca7b3ca27019d71c79acbdea18cb
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

NOX4 PRDM1

1.08e-0391242104d2ab9fe5cc404388c32fafb34e421c2e138be
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Esophagus_Squamous_Cell_Carcinoma-7|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

MED12L GLI2

1.13e-03932424ab8c28f7c47129ac633bcfdc7ccc8f7793464d5
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

NOX4 GLI2

1.49e-0310724213af691c8533418d2800a8eca61155896b559948
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)|Hippocampus / BrainAtlas - Mouse McCarroll V32

NOX4 GLI2

1.49e-03107242a5a34bb9706527799ddb494d4f1bfc634c29e8a9
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 RHBDL1

1.58e-03110242c80d1c3df75648e2c8f6832279c2acca63d76681
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

ENPP5 COL8A1

1.69e-03114242656072c25258d4c00f24f6ba17de6a5db891e7be
ToppCellLV-03._Atrial_Cardiomyocyte|LV / Chamber and Cluster_Paper

THSD4 CBX4

1.87e-031202423b77bd0e3630cdd45001cecf5e47660a90ebc92e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Interneuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

DRP2 PRDM1

1.90e-03121242b2d571f571133c281d72584fe925cebbd2317829
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NOX4 GLI2

1.90e-031212425035e071033cb76a7fc0128716755b14821e8f05
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NOX4 GLI2

1.90e-03121242c96115bd33455296378a257583b49442d00b39ca
ToppCell|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCD2 DOCK3

1.90e-03121242da8fe561dcf50792d0cbcaad383d564f900a6677
ToppCellRV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

THSD4 DOCK3

1.94e-031222421cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-AT1_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RHBDL1 DRP2

2.03e-03125242b1a12400f7070bdf09e87974c548a8b82e92b65e
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-mesenchymal_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 COL8A1

2.06e-03126242c3261ea8726400de87f1c8a5a5134ba2b2884f66
ToppCellLPS-IL1RA-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NOX4 CBX4

2.09e-031272426b24630978eb0772b4cd3bf59e5bc4390be47619
ToppCellLV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

THSD4 CBX4

2.19e-03130242a3e12984fb61311e49cc76c59f74f4dffc48faa1
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-|Striatum / BrainAtlas - Mouse McCarroll V32

NOX4 COL8A1

2.33e-03134242a3547a68012d879d4dfe80394eace70808722e43
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)|Striatum / BrainAtlas - Mouse McCarroll V32

NOX4 COL8A1

2.33e-031342429458e2d0dbc18d9025b66b59f3ecc2fbc5384940
ToppCellIIH-CD4-CD8_2|IIH / Condition, Cell_class and T cell subcluster

ABCD2 NOX4

2.43e-031372425614a086f5f698e0965f3c7699cffefec5c3b87e
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c3-LAMP3|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L DOCK3

2.50e-03139242bb2b020dda32ddc60ec9952de5b01acee60b5b59
ToppCellCOVID-19_Mild-Neu_0|World / 5 Neutrophil clusters in COVID-19 patients

ABCD2 LRRTM4

2.54e-0314024293f024473b1bb3bf93ae776fd6a8fc5e93d013f0
ToppCellAT1-AT2_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

THSD4 COL8A1

2.54e-0314024245d52a086ced8d58e01ac51ac4a90338e8649b16
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

THSD4 NOX4

2.57e-03141242a32947b13e888850c979a54c137512e4b96d2f36
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

THSD4 NOX4

2.57e-031412422cb651d63466fdcce011d1dd8de409ef439d03e7
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 NFS1

2.61e-03142242a05b320cf182b2aaf18df7c40045dc65b659bf20
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 NFS1

2.61e-03142242d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCellLPS-antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCD2 PRDM1

2.64e-0314324257ee1830d96d73d92b5f83b028592a5d952c6013
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BCLAF3 THSD4

2.64e-03143242b4ed3855652fdf32f97cb7c18cab4f4f4c24d5c7
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L ENPP5

2.72e-03145242b17699f7f98d2361a4d26c26f52db05e7ff69dff
ToppCellLPS-IL1RA-Endothelial-Mes-Like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NOX4 LRRTM4

2.72e-0314524290ca38c02325c5c637c32efdef634b54cc3cd105
ToppCellHealthy-B_cell|World / disease group, cell group and cell class

ENPP5 CBX4

2.75e-03146242588359d3df6ad7090b7fa6c7f8d29cc1717e7f4f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK3 PRDM1

2.79e-031472425e6dd2ddc67b3722f6528e7277cbc7f296098687
ToppCellLeuk-UTI-Lymphocyte-T_NK-CD8_TCM|Leuk-UTI / Disease, Lineage and Cell Type

DOCK3 PRDM1

2.90e-031502420a65f5e2f4e0b0e822b029e0222b28ba2db89e6d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL8A1 GLI2

2.90e-031502427a9d6a7ff8000e9a061e1b586e4c258cc91a2a09
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL8A1 GLI2

2.90e-03150242e5b843cb2bc847f6cab4cbec0a2a6a72fac50fee
Diseasefat body mass

MED12L THSD4 DOCK3

6.23e-04217233EFO_0005409
Diseaseaortic measurement

THSD4 CHSY1 NOX4

9.50e-04251233EFO_0020865
Diseasesunburn

NOX4 ARID1B

2.53e-0396232EFO_0003958
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

UBAP2L ARID1B LRRTM4 REV3L

3.16e-03801234EFO_0003888, EFO_0007052, MONDO_0002491
DiseasePolydactyly

GLI2 KIAA0586

3.73e-03117232C0152427
Diseaseacne

GLI2 PRDM1

4.25e-03125232EFO_0003894
Diseasemelanoma

DOCK3 NOX4

4.32e-03126232EFO_0000756
Diseasecup-to-disc ratio measurement

THSD4 CHSY1 COL8A1

4.38e-03430233EFO_0006939
Diseasecolorectal cancer (is_marker_for)

HDAC1 PRDM1

6.61e-03157232DOID:9256 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
YEGVLYKPPPQHMFY

ABCD2

531

Q9UBJ2
YPQQPNYKRHMDGMY

ARID1B

1436

Q8NFD5
MYTYMLPHSYHKPAQ

OR2T1

306

O43869
LYHTHPMPKPRSYYL

MED12L

1711

Q86YW9
CEMPHHMKPLPYYSY

LRRTM4

516

Q86VH4
AMLPYLINYYGNPHS

NFS1

76

Q9Y697
YPGVQNHEMYDYLLH

MERTK

801

Q12866
NYYYGQGHPMKPHRI

HDAC1

21

Q13547
DYLYKVPTPHFHYIM

ENPP5

41

Q9UJA9
YYHQMTLVAGHPAPY

GLI2

176

P10070
LYNQGPEYHYLHQML

NOX4

36

Q9NPH5
YHIYPPTAPHVAYMQ

PAN3

421

Q58A45
QYMPKYSEGIPYKEH

BCLAF3

111

A2AJT9
YHHMQLAYPNPRYQG

DOCK3

1711

Q8IZD9
YYQLNSKKHHPYQPD

CBX4

151

O00257
HLQYGKEYPHLPQYM

COL8A1

76

P27658
GNKLHYPIMEYYTPT

DRP2

646

Q13474
YNAHYPKFLLPPYGM

PRDM1

406

O75626
YHPEYMKSPLVYHPG

RHBDL1

226

O75783
NKNPPYQYRLHSYML

CHSY1

306

Q86X52
HAYPPQVYGYDDLQM

UBAP2L

811

Q14157
MNKFYQPHEAHIPYL

REV3L

146

O60673
YMIHQQPNPGVHYEY

THSD4

511

Q6ZMP0
DYMLQVYGKPVYQGH

KIAA0586

626

Q9BVV6