Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

IL11 ASXL1 PPRC1 ALX4 CASZ1 RAPGEF3 ZMIZ2 PKD1 NLRC5 KMT2A PLAG1 TAF4 HNF1A CRTC3 PRRX1 TCF12 TFAP2D GPER1 NRL CALCOCO1 ZNF629 GLIS3 POU2F1 CHD7 NR3C1 CREBBP ARID2 SIX5 ZFHX3 SMO MYOCD ARID3C AGRN

4.13e-07139018933GO:0045944
GeneOntologyBiologicalProcessanimal organ morphogenesis

ASXL1 DLG5 GAK SLC39A1 NKX3-2 LGR4 ALX4 CASZ1 BMP10 ACAN PKD1 FSCN2 PKP2 PLAG1 ATG9A HNF1A PRRX1 NRL DUOX2 POU2F1 CHD7 NR3C1 LEFTY2 COL18A1 LEFTY1 ARID2 ANKRD11 SMO SCRIB PCNT

1.64e-06126918930GO:0009887
GeneOntologyBiologicalProcesscognition

TACO1 ITGA5 ADCY1 TTBK1 NRXN2 RAPGEF3 KMT2A NTSR1 CHD7 ATXN1L CREBBP SLC1A4 SHISA7 RIN1 ANKRD11

8.79e-0642318915GO:0050890
GeneOntologyBiologicalProcessnodal receptor complex assembly

LEFTY2 LEFTY1

8.35e-0521892GO:0038099
GeneOntologyBiologicalProcessnegative regulation of nodal receptor complex assembly

LEFTY2 LEFTY1

8.35e-0521892GO:1900124
GeneOntologyBiologicalProcessregulation of nodal receptor complex assembly

LEFTY2 LEFTY1

8.35e-0521892GO:1900123
MousePhenoabnormal lateral ventricle morphology

DLG5 MYCBP2 PKD1 HSD17B2 ANK2 POMGNT1 CHD7 ATXN1L COL18A1 SCRIB

2.10e-0516416210MP:0000823
MousePhenohydrocephaly

STK36 DLG5 SPAST RABGAP1 SOCS7 PKD1 HSD17B2 POMGNT1 CHD7 ATXN1L COL18A1

3.19e-0520916211MP:0001891
MousePhenodecreased fetal cardiomyocyte proliferation

CASZ1 BMP10 CHD7 ARID2

4.69e-05181624MP:0011395
MousePhenoabnormal optic nerve morphology

TACO1 RABGAP1 CANT1 ANK2 PPFIA2 POMGNT1 SLC4A3 SPTBN4 COL18A1 SCRIB

5.12e-0518216210MP:0001330
MousePhenoabnormal brain ventricular system morphology

STK36 DLG5 SPAST MYCBP2 RABGAP1 SOCS7 PKD1 HSD17B2 ANK2 POMGNT1 CHD7 ATXN1L COL18A1 SCRIB PCNT

5.26e-0539316215MP:0002200
MousePhenoabnormal gait

TACO1 DLG5 SPAST APC2 WDR81 IREB2 RABGAP1 ADCY1 NRXN2 ACAN OSTM1 PPFIA2 PRX SPTBN4 LEFTY2 LEFTY1 SCRIB

1.13e-0452016217MP:0001406
MousePhenodilated lateral ventricle

DLG5 MYCBP2 PKD1 POMGNT1 CHD7 COL18A1

1.13e-04661626MP:0000825
MousePhenoabnormal left renal vein morphology

LEFTY2 LEFTY1

1.33e-0421622MP:0011327
MousePhenoabnormal renal vein morphology

LEFTY2 LEFTY1

1.33e-0421622MP:0011323
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 STK36 MYCBP2 PPRC1 IRS1 ITGA5 CASZ1 BAP1 CANT1 ZMIZ2 PKD1 NLRC5 ATG9A CRAMP1 TEX19 SEMA6B SH2B3 NTSR1 NSD1 POMGNT1 TNRC6C SLC1A5 KCNH3 NHSL1 KANK3 ANKRD11 PKN1 LRRC14 AGRN AHNAK2 PCNT PPP1R16A

2.60e-1411051953235748872
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DLG5 GAPVD1 DENND4A SPAST AFTPH MYCBP2 IRS1 ARHGEF16 RBSN PKP2 KMT2A TNS3 KIF13B CRTC3 CARMIL2 ZNF629 SLC1A5 NHSL1 ANKRD11 FAM53B SCRIB AHNAK2

3.89e-098611952236931259
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RNF130 COL26A1 MYCBP2 RABGAP1 ARHGEF16 ADCY1 SLC25A37 ALX4 CASZ1 ZBTB7A PCYOX1L PTPRN2 NLRC5 OS9 TAF4 CRAMP1 PPFIA2 CALCOCO1 TPGS1 TNRC6C CREBBP SPTBN4 COL18A1 ATP2C1 ANKRD11 ZFHX3 PKN1 FGGY PCNT

5.40e-0914891952928611215
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MYCBP2 APC2 WDR81 DDB1 AP1B1 PTPRN2 TAF4 HOMER3 KIF13B RANBP2 ANK2 CALCOCO1 NSD1 CHD7 SHISA7 SPTBN4 PKN1 SCRIB AGRN PCNT

5.71e-079631952028671696
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

RNF130 CENPB ALX4 RBSN ZMIZ2 KMT2A PLAG1 NR0B2 HNF1A PRRX1 TCF12 POU2F1 NR3C1 CREBBP THAP7 SIX5 ZFHX3

6.05e-077091951722988430
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

GAPVD1 MYCBP2 RABGAP1 BAP1 ZMIZ2 KIAA1958 HSPA6 RANBP2 ZBTB9 TPGS1 CHD7 ZFHX3 PCNT

7.92e-074181951334709266
Pubmed

Human transcription factor protein interaction networks.

ASXL1 PSMB5 PSMD4 DDB1 BAP1 ZBTB7A ZMIZ2 KMT2A TAF4 HNF1A TCF12 ZNF629 ZBTB9 POU2F1 TPGS1 CHD7 TNRC6C ATXN1L CREBBP SLC1A5 PRCC ARID2 SIX5 ZFHX3

1.77e-0614291952435140242
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

DENND4A CENPB ZNF623 DDB1 ALX4 NR0B2 HNF1A PRRX1 TCF12 TFAP2D CALCOCO1 GLIS3 ZBTB9 POU2F1 NR3C1 CREBBP THAP7 MYOCD

2.55e-068771951820211142
Pubmed

Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity.

BAP1 PCLO ARID2

3.43e-066195325636086
Pubmed

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R asymmetry by the mouse node.

NKX3-2 LEFTY2 LEFTY1 SMO

4.33e-0620195411440720
Pubmed

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node.

NKX3-2 LEFTY2 LEFTY1 SMO

4.33e-0620195411517919
Pubmed

Interaction network of human early embryonic transcription factors.

ZMIZ2 KMT2A TAF4 RANBP2 ZBTB9 POU2F1 CHD7 ATXN1L CREBBP ARID2 ZFHX3

5.29e-063511951138297188
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

GAPVD1 AFTPH MYCBP2 BAP1 ZBTB7A KIAA1958 KMT2A MN1 RANBP2 POU2F1 CHD7 PPL CHTF18 PKN1 SCRIB SON

8.59e-067741951615302935
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

COL26A1 ITGA5 LEFTY2 COL18A1 AGRN

9.09e-0650195523658023
Pubmed

Morphogenetic lung defects of JSAP1-deficient embryos proceeds via the disruptions of the normal expressions of cytoskeletal and chaperone proteins.

POU2F1 LEFTY2 LEFTY1 SMO

1.11e-0525195418324732
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

DLG5 AFTPH CASZ1 ZBTB7A KMT2A OS9 NOL7 TAF4 HSPA6 HOMER3 RANBP2 TFAP2D NSD1 CHD7 SLC3A2 RMDN3 COL18A1 ARID2 LRCH4 ANKRD11 ZFHX3 AGRN SON

1.25e-0514971952331527615
Pubmed

Identification of novel CBP interacting proteins in embryonic orofacial tissue.

GAK AP1B1 CREBBP

1.42e-059195315752756
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

IL10RA DLG5 CD109 IREB2 HMOX1 FCSK PTPRN2 PKP2 TICRR CREBBP NFE2L3 CD93 THBS2 FAM53B FHDC1 FGGY

1.59e-058141951623251661
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

SPAST MYCBP2 NARS1 AP1B1 ZMIZ2 KIAA1958 KMT2A TAF4 HOMER3 RANBP2 TCF12 ZNF629 ZBTB9 POU2F1 CHD7 ATXN1L CREBBP SLC3A2 ARID2

1.60e-0511031951934189442
Pubmed

A census of human transcription factors: function, expression and evolution.

NKX3-2 ALX4 ZBTB7A KMT2A PLAG1 CRAMP1 HNF1A PRRX1 TCF12 TFAP2D NRL POU2F1 NR3C1 THAP7 NFE2L3 SIX5 ZFHX3

1.60e-059081951719274049
Pubmed

Genomic analysis of mouse retinal development.

GAK ZNF623 SLC25A37 CASZ1 RBSN NRXN2 PKD1 KMT2A NOL7 PRRX1 TCF12 NRL ZNF629 NSD1 PITPNM3 FAM53B PCMTD2 AGRN

1.64e-0510061951815226823
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ITGA5 CASZ1 AP1B1 PTPRN2 NOL7 HOMER3 CHD7 NR3C1 CREBBP SLC3A2 ARID2 APOL6 PITPNM3 AHNAK2

1.66e-056381951431182584
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

GAK MYCBP2 LGR4 KMT2A RANBP2 SLC1A5 SLC3A2 SCRIB

2.00e-05202195824639526
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

ASXL1 SLC25A37 PLAG1 TNS3 NSD1 CREBBP ANKRD11 SCRIB SON AHNAK2

2.00e-053321951037433992
Pubmed

The functions of the HIV1 protein Vpr and its action through the DCAF1.DDB1.Cullin4 ubiquitin ligase.

DDB1 NR3C1 CREBBP

2.02e-0510195320347598
Pubmed

Phospho-tyrosine dependent protein-protein interaction network.

STK36 CENPB KRTAP23-1 IRS1 RABGAP1 SH2B3 GLIS3 MAGEC3 LEFTY2 RIN1 CHTF18

2.25e-054101951125814554
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

GAPVD1 GAK AFTPH PSMD4 DDB1 KMT2A RANBP2 ANK2 NR3C1 SLC1A5 SLC3A2 PRCC ARID2 SCRIB SON AHNAK2 PCNT

2.29e-059341951733916271
Pubmed

A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein.

HSPA1L HSPA6 NR3C1 SCRIB PLCE1

2.43e-0561195519875381
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

STK36 ZNF623 LCMT2 CASZ1 TTBK1 KIF13B ZNF629 PRX ATP2C1 ARID2 LRRC14 FHDC1

2.48e-054931951215368895
Pubmed

Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination.

PKD1 LEFTY2 LEFTY1

2.77e-0511195327272319
Pubmed

Expression patterns of vHNF1 and HNF1 homeoproteins in early postimplantation embryos suggest distinct and sequential developmental roles.

HNF1A LEFTY2 LEFTY1

2.77e-051119531363228
Pubmed

The SIL gene is required for mouse embryonic axial development and left-right specification.

LEFTY2 LEFTY1 SMO

2.77e-0511195310385121
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

DDB1 ZBTB7A TAF4 RANBP2 ZNF629 ZBTB9 CHD7 ATXN1L SLC1A5 SLC3A2 ZFHX3 SCRIB SON

2.83e-055831951329844126
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

TACO1 ASXL1 GAPVD1 CENPB ALX4 CASZ1 BAP1 HSPA1L RANBP2 TCF12 POU2F1 NR3C1 CREBBP RMDN3 SIX5 SCRIB

2.97e-058571951625609649
Pubmed

circASXL1-1 regulates BAP1 deubiquitinase activity in leukemia.

ASXL1 BAP1

3.13e-052195231780633
Pubmed

LEFTY2 alleviates hepatic stellate cell activation and liver fibrosis by regulating the TGF-β1/Smad3 pathway.

LEFTY2 LEFTY1

3.13e-052195232745796
Pubmed

Structural basis of histone H2A lysine 119 deubiquitination by Polycomb Repressive Deubiquitinase BAP1/ASXL1.

ASXL1 BAP1

3.13e-052195236865140
Pubmed

Cooperativity in transcription factor binding to the coactivator CREB-binding protein (CBP). The mixed lineage leukemia protein (MLL) activation domain binds to an allosteric site on the KIX domain.

KMT2A CREBBP

3.13e-052195212205094
Pubmed

Reduced BAP1 activity prevents ASXL1 truncation-driven myeloid malignancy in vivo.

ASXL1 BAP1

3.13e-052195229743720
Pubmed

Heme oxygenase-1 and interleukin-11 are overexpressed in stress-induced premature senescence of human WI-38 fibroblasts induced by tert-butylhydroperoxide and ethanol.

IL11 HMOX1

3.13e-052195217295091
Pubmed

LEFTY, a member of the transforming growth factor-beta superfamily, inhibits uterine stromal cell differentiation: a novel autocrine role.

LEFTY2 LEFTY1

3.13e-052195220056823
Pubmed

Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development.

LEFTY2 LEFTY1

3.13e-052195210053005
Pubmed

Ankyrin-B directs membrane tethering of periaxin and is required for maintenance of lens fiber cell hexagonal shape and mechanics.

ANK2 PRX

3.13e-052195226538089
Pubmed

Mutation analysis of human LEFTY A and LEFTY B genes in children with Ivemark syndrome.

LEFTY2 LEFTY1

3.13e-052195211100524
Pubmed

Lefty1 and lefty2 control the balance between self-renewal and pluripotent differentiation of mouse embryonic stem cells.

LEFTY2 LEFTY1

3.13e-052195224147624
Pubmed

Polarity protein SCRIB interacts with SLC3A2 to regulate proliferation and tamoxifen resistance in ER+ breast cancer.

SLC3A2 SCRIB

3.13e-052195235501367
Pubmed

The l-isomer-selective transport of aspartic acid is mediated by ASCT2 at the blood-brain barrier.

SLC1A4 SLC1A5

3.13e-052195214622120
Pubmed

N-linked glycosylation and sequence changes in a critical negative control region of the ASCT1 and ASCT2 neutral amino acid transporters determine their retroviral receptor functions.

SLC1A4 SLC1A5

3.13e-052195212584318
Pubmed

Reducing hyperactivated BAP1 attenuates mutant ASXL1-driven myeloid malignancies in human haematopoietic cells.

ASXL1 BAP1

3.13e-052195234186160
Pubmed

Small Heterodimer Partner Controls the Virus-Mediated Antiviral Immune Response by Targeting CREB-Binding Protein in the Nucleus.

NR0B2 CREBBP

3.13e-052195231091449
Pubmed

Heme Oxygenase 1 Impairs Glucocorticoid Receptor Activity in Prostate Cancer.

HMOX1 NR3C1

3.13e-052195230813528
Pubmed

Sodium-dependent neutral amino acid transporter type 1 is an auxiliary receptor for baboon endogenous retrovirus.

SLC1A4 SLC1A5

3.13e-052195210933718
Pubmed

Gly972Arg of IRS-1 and Lys121Gln of PC-1 polymorphisms act in opposite way in polycystic ovary syndrome.

IRS1 PKD1

3.13e-052195227785750
Pubmed

Lefty antagonises TGF-beta1 induced epithelial-mesenchymal transition in tubular epithelial cells.

LEFTY2 LEFTY1

3.13e-052195220171171
Pubmed

Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily.

LEFTY2 LEFTY1

3.13e-05219529496783
Pubmed

A functional role of LEFTY during progesterone therapy for endometrial carcinoma.

LEFTY2 LEFTY1

3.13e-052195229268772
Pubmed

Phenylglycine analogs are inhibitors of the neutral amino acid transporters ASCT1 and ASCT2 and enhance NMDA receptor-mediated LTP in rat visual cortex slices.

SLC1A4 SLC1A5

3.13e-052195228807674
Pubmed

Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis.

ASXL1 BAP1

3.13e-052195230013160
Pubmed

Inhibitors of the Neutral Amino Acid Transporters ASCT1 and ASCT2 Are Effective in In Vivo Models of Schizophrenia and Visual Dysfunction.

SLC1A4 SLC1A5

3.13e-052195230171039
Pubmed

Phosphorylation of glucocorticoid receptor tau1c transactivation domain enhances binding to CREB binding protein (CBP) TAZ2.

NR3C1 CREBBP

3.13e-052195225511704
Pubmed

ASCT1 (Slc1a4) transporter is a physiologic regulator of brain d-serine and neurodevelopment.

SLC1A4 SLC1A5

3.13e-052195230185558
Pubmed

Lefty1 Ameliorates Post-infarction Fibrosis by Suppressing p-Smad2 and p-ERK1/2 Signaling Pathways.

LEFTY2 LEFTY1

3.13e-052195233409963
Pubmed

LEFTY2 inhibits endometrial receptivity by downregulating Orai1 expression and store-operated Ca2+ entry.

LEFTY2 LEFTY1

3.13e-052195229230527
Pubmed

Molecular analysis of LEFTY-expressing cells in early human embryoid bodies.

LEFTY2 LEFTY1

3.13e-052195217038673
Pubmed

Epigenetic targeted therapy of stabilized BAP1 in ASXL1 gain-of-function mutated leukemia.

ASXL1 BAP1

3.13e-052195235122023
Pubmed

Leu628 of the KIX domain of CBP is a key residue for the interaction with the MLL transactivation domain.

KMT2A CREBBP

3.13e-052195220969867
Pubmed

Anti-inflammatory effects of Lefty-1 in renal tubulointerstitial inflammation via regulation of the NF-κB pathway.

LEFTY2 LEFTY1

3.13e-052195229286065
Pubmed

Structural Analysis of the Glucocorticoid Receptor Ligand-Binding Domain in Complex with Triamcinolone Acetonide and a Fragment of the Atypical Coregulator, Small Heterodimer Partner.

NR0B2 NR3C1

3.13e-052195228396564
Pubmed

Isolation, characterization, and function of EBAF/LEFTY B: role in infertility.

LEFTY2 LEFTY1

3.13e-052195221401636
Pubmed

Interaction of endostatin with integrins implicated in angiogenesis.

ITGA5 COL18A1

3.13e-052195211158588
Pubmed

Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1.

ASXL1 BAP1

3.13e-052195237556531
Pubmed

Lnk adaptor suppresses radiation resistance and radiation-induced B-cell malignancies by inhibiting IL-11 signaling.

IL11 SH2B3

3.13e-052195224297922
Pubmed

Lefty is expressed in mouse endometrium in estrous cycle and peri-implantation period.

LEFTY2 LEFTY1

3.13e-052195215640253
Pubmed

Hepatocyte nuclear factor-1alpha regulates glucocorticoid receptor expression to control postnatal body growth.

HNF1A NR3C1

3.13e-052195218583462
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

STK36 AFTPH APC2 ZMIZ2 CRTC3 GLIS3 CHD7 PRX ARID2 SON PCNT

3.47e-054301951135044719
Pubmed

Hydroxysteroid (17beta) dehydrogenase 7 activity is essential for fetal de novo cholesterol synthesis and for neuroectodermal survival and cardiovascular differentiation in early mouse embryos.

LEFTY2 LEFTY1 SMO

3.68e-0512195320185768
Pubmed

Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.

ATG9A TNS3 RANBP2 GLIS3 CREBBP RIN1

3.80e-05110195637219487
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

GAPVD1 GAK PSMB5 CD109 PSMD4 DDB1 AP1B1 PTPRN2 OS9 TNS3 RANBP2 NAGK SLC1A5 PPL SLC3A2 RMDN3 ATP2C1

3.87e-059741951728675297
Pubmed

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors.

GAK BAP1 CANT1 ATG9A NR0B2 CREBBP RIN1 CHTF18 ARID2 SON

3.89e-053591951035559673
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

CD109 ITGA5 PCYOX1L OS9 SLC1A5 SLC3A2 AGRN

4.14e-05164195732409323
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ASXL1 MYCBP2 BAP1 NRXN2 CHD7 TNRC6C SCRIB PCNT

4.31e-05225195812168954
Pubmed

Region-specific endodermal signals direct neural crest cells to form the three middle ear ossicles.

NKX3-2 ACAN SMO

4.76e-0513195330630826
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

MYCBP2 PSMB5 WDR81 DDB1 AP1B1 KMT2A HSPA1L NAGK PCLO SLC1A5 SLC3A2 RMDN3 ZFHX3 MYOCD AHNAK2

5.56e-058071951530575818
Pubmed

Pattern and polarity in the development and evolution of the gnathostome jaw: both conservation and heterotopy in the branchial arches of the shark, Scyliorhinus canicula.

NKX3-2 ALX4 PRRX1

6.04e-0514195323473983
Pubmed

E protein silencing by the leukemogenic AML1-ETO fusion protein.

TAF4 TCF12 CREBBP

6.04e-0514195315333839
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

CENPB WDR81 IREB2 RBSN AP1B1 NOL7 ATG9A SPCS1 SLC1A4 RIN1 LRRC14 SCRIB AGRN PPP1R16A

6.05e-057191951435337019
Pubmed

Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico.

ASXL1 PLAG1 CHD7 CD93

6.76e-0539195425859222
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

MYCBP2 TCF12 TNRC6C SLC3A2 SON

7.04e-0576195527542412
Pubmed

Essential roles of fibronectin in the development of the left-right embryonic body plan.

ITGA5 LEFTY2 LEFTY1

7.51e-0515195321466802
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYCBP2 PSMB5 NARS1 PSMD4 DDB1 PKP2 HSPA1L HSPA6 TNS3 RANBP2 CHD7 CREBBP SLC1A5 SLC3A2 RIN1 CHTF18 SCRIB AGRN SON AHNAK2

8.11e-0513531952029467282
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DENND4A PSMB5 AP1B1 KMT2A TCF12 ZNF629 NR3C1 PRCC CHTF18 LRCH4 SCRIB AGRN PLCE1

8.53e-056501951338777146
Pubmed

Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.

IL10RA PSMD4 ADCY1 CANT1 ZMIZ2 TCF12 DEXI NHSL1

8.76e-0524919589371744
Pubmed

Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers.

ANK2 PRX SPTBN4

9.21e-0516195321745462
Pubmed

Nodal and lefty signaling regulates the growth of pancreatic cells.

LEFTY2 LEFTY1

9.35e-053195218393305
Pubmed

Lefty-1 inhibits renal epithelial-mesenchymal transition by antagonizing the TGF-β/Smad signaling pathway.

LEFTY2 LEFTY1

9.35e-053195232065356
Pubmed

Abnormal gene expression and regulation in the liver of jvs mice with systemic carnitine deficiency.

HNF1A NR3C1

9.35e-05319527914432
Pubmed

Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells.

ASXL1 BAP1

9.35e-053195229345617
Pubmed

Role of asymmetric signals in left-right patterning in the mouse.

LEFTY2 LEFTY1

9.35e-053195211471154
Pubmed

betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system.

PTPRN2 SPTBN4

9.35e-053195211086001
Pubmed

Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and lefty processing.

LEFTY2 LEFTY1

9.35e-053195216141390
InteractionYWHAH interactions

DLG5 GAPVD1 DENND4A SPAST AFTPH MYCBP2 IRS1 ARHGEF16 BAP1 RBSN PKP2 KMT2A ATG9A HOMER3 TNS3 KIF13B TICRR CRTC3 CARMIL2 ZNF629 NR3C1 ATXN1L CREBBP SLC1A5 NHSL1 RMDN3 RIN1 ANKRD11 FAM53B SCRIB AHNAK2 PCNT

1.83e-08110219332int:YWHAH
InteractionFEV interactions

PSMB5 BAP1 ZBTB7A KMT2A TAF4 POU2F1 CHD7 ATXN1L CREBBP ARID2 SIX5 ZFHX3

6.31e-0720319312int:FEV
InteractionTOP3B interactions

VWA5B2 STK36 MYCBP2 PPRC1 IREB2 IRS1 ITGA5 CASZ1 BAP1 CANT1 ZMIZ2 PKD1 PKP2 NLRC5 ATG9A CRAMP1 TEX19 SEMA6B SH2B3 NTSR1 NSD1 POMGNT1 TNRC6C SLC1A5 KCNH3 NHSL1 KANK3 ANKRD11 PKN1 LRRC14 AGRN AHNAK2 PCNT PPP1R16A

1.36e-06147019334int:TOP3B
InteractionFOXL1 interactions

GAPVD1 CENPB RANBP2 POU2F1 CHD7 NR3C1 ATXN1L RMDN3 SIX5 ZFHX3 SCRIB

3.10e-0619619311int:FOXL1
InteractionAFDN interactions

DLG5 SPAST LGR4 BAP1 NRXN2 NECTIN4 PKP2 KMT2A KIF13B TPGS1 SLC1A5 SLC3A2 RIN1 SCRIB

4.25e-0633319314int:AFDN
InteractionYWHAG interactions

DLG5 GAPVD1 DENND4A SPAST AFTPH MYCBP2 LGR4 IRS1 ARHGEF16 BAP1 TTBK1 PKP2 KMT2A ATG9A TNS3 KIF13B TICRR HNF1A CRTC3 CARMIL2 ZNF629 NHSL1 RMDN3 RIN1 ANKRD11 FAM53B SCRIB SON AHNAK2

8.32e-06124819329int:YWHAG
InteractionTLE3 interactions

DDB1 BAP1 ZMIZ2 KMT2A TAF4 CRTC3 TCF12 NR3C1 ATXN1L CREBBP SPTBN4 ARID2 ZFHX3 SON

1.68e-0537619314int:TLE3
InteractionPHF21A interactions

GAPVD1 MYCBP2 RABGAP1 DDB1 BAP1 ZMIZ2 HSPA6 RANBP2 ZBTB9 TPGS1 CHD7 ZFHX3 PCNT

2.81e-0534319313int:PHF21A
InteractionYWHAB interactions

DLG5 GAPVD1 DENND4A MYCBP2 IRS1 ARHGEF16 BAP1 PKP2 KMT2A ATG9A TNS3 KIF13B TICRR HNF1A CRTC3 CARMIL2 ZNF629 NHSL1 RMDN3 RIN1 FAM53B SCRIB SON AHNAK2

4.04e-05101419324int:YWHAB
InteractionYWHAZ interactions

ASXL1 DLG5 GAPVD1 DENND4A MYCBP2 LGR4 IRS1 ARHGEF16 BAP1 PKP2 KMT2A ATG9A HOMER3 KIF13B TICRR HNF1A CRTC3 CARMIL2 SH2B3 PPFIA2 ZNF629 NHSL1 RMDN3 RIN1 PRCC FAM53B SCRIB PCNT

6.10e-05131919328int:YWHAZ
InteractionBAG4 interactions

PSMB5 CASZ1 BAP1 SCGB3A1 SUOX PKP2 HSPA1L HSPA6 TFAP2D CD93

6.25e-0522419310int:BAG4
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY1 GJA3 MYLK4 PKP2 NR0B2 ASB14 SLC4A3 MYOCD LGR6

1.40e-071861959337f768cc43db2db96ba6495b076006b1a5b0331
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY1 GJA3 MYLK4 PKP2 NR0B2 ASB14 SLC4A3 MYOCD LGR6

1.40e-071861959e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY1 SOCS7 NECTIN4 CARMIL2 PPFIA2 PCLO CHD7 GALNT9 PITPNM3

1.46e-0718719591b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC2A10 TNS3 PRRX1 SLC1A5 PPL NFE2L3 THBS2 SMO PLCE1

1.83e-0719219590dc1f46e40346ed0b286e53b106a812441575100
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CD109 CD320 ITGA5 GPER1 CD93 KANK3 PITPNM3 AGRN AHNAK2

2.48e-07199195970e05d7c0c68c28754ce0e72434b205aed6287ae
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GJA3 ACAN PPFIA2 DUOX2 MYOCD LGR6 AHNAK2 PLCE1

3.71e-071521958bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GJA3 ACAN PPFIA2 DUOX2 MYOCD LGR6 AHNAK2 PLCE1

3.71e-071521958ee329249a034a969a16b26a224aa04249d67382d
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA MYCBP2 CD109 GLIS3 SLC4A3 SHISA7 NFE2L3 GALNT9

9.47e-0717219583f784aed340b50ddbec3f7dc0a5279180d38a2bb
ToppCell(05)_Ciliated-(2)_48hpi|(05)_Ciliated / shred by cell type and Timepoint

COL26A1 PLAG1 HSPA1L NR0B2 SEMA6B CARMIL2 KANK3

1.27e-061241957fc8cce8c1809edafbc4e69e501dd4f016f5dfc0b
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 ADCY1 PTPRN2 FAM234B CARMIL2 ANK2 GPER1 AMER3

1.28e-061791958878b15ea62e3405682a538f79f58d74b9cd3f398
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD109 CRTC3 GPER1 SLC4A3 SIX5 ZFHX3 MYOCD PLCE1

1.45e-061821958ffe500d78a89dc6b4d05bab1664e7f30c94fb8d9
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN2 ANK2 GLIS3 DUOX2 NHSL1 COL18A1 ARID3C PLCE1

1.64e-0618519583a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCelldroplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN2 ANK2 GLIS3 DUOX2 NHSL1 COL18A1 ARID3C PLCE1

1.64e-061851958224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADCY1 ACAN PRRX1 THBS2 ZFHX3 MYOCD LGR6 PLCE1

1.70e-061861958a95744b8649096bd7cfc3591a02841fa411085b3
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAPLN4 NRXN2 PTPRN2 PCLO KCNH3 SPTBN4 LEFTY2 GALNT9

1.77e-061871958e04a84989d624378141042768383b9c846901f2d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAPLN4 NRXN2 PTPRN2 PCLO KCNH3 SPTBN4 LEFTY2 GALNT9

1.77e-06187195824cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAPLN4 NRXN2 PTPRN2 PCLO KCNH3 SPTBN4 LEFTY2 GALNT9

1.77e-0618719582f153b203fe79f206319603cf94d3a03ab49a05d
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY1 GJA3 BMP10 PKP2 ASB14 SLC4A3 MYOCD LGR6

1.92e-061891958e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY1 GJA3 BMP10 PKP2 ASB14 SLC4A3 MYOCD LGR6

1.92e-061891958b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRXN2 ANK2 GLIS3 DUOX2 NHSL1 COL18A1 ARID3C PLCE1

2.00e-061901958f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRXN2 ANK2 GLIS3 DUOX2 NHSL1 COL18A1 ARID3C PLCE1

2.00e-061901958a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRXN2 ANK2 GLIS3 DUOX2 NHSL1 COL18A1 ARID3C PLCE1

2.00e-06190195857c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL11 CD109 MN1 PRRX1 SLC4A3 THBS2 APOL6 PLCE1

2.08e-061911958b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNF130 HMOX1 SLC25A37 MN1 SH2B3 NTSR1 CD93 CD68

2.16e-061921958f14ee74ac3275601749a23c5efe39c2413a62e1a
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF130 HMOX1 SLC25A37 MN1 SH2B3 NTSR1 CD93 CD68

2.16e-0619219580219093e7921a0db78053aee13ec480b520f5662
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 ADCY1 NRXN2 PCLO SLC4A3 SHISA7 KCNH3 SPTBN4

2.24e-061931958be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAMDC2 ACAN MYLK4 PRRX1 ADAMTS2 ZFHX3 MYOCD PLCE1

2.24e-061931958469a7f1c2ff7137cc5a064464456911f67f92e70
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAMDC2 ACAN MYLK4 PRRX1 ADAMTS2 ZFHX3 MYOCD PLCE1

2.24e-061931958323d1f3f4fbeb93ba857fc135d8aa0b897f98ac5
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 ADCY1 NRXN2 PCLO SLC4A3 SHISA7 KCNH3 SPTBN4

2.24e-0619319580c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 ADCY1 NRXN2 PCLO SLC4A3 SHISA7 KCNH3 SPTBN4

2.24e-0619319588689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CD109 CD320 ITGA5 ADCY1 RAPGEF3 GPER1 CD93 AGRN

2.42e-061951958a432d69b0172211ee4d53675936a1dc9ce1ae1f0
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOK6 ACAN PPFIA2 COL18A1 ZFHX3 MYOCD LGR6 PLCE1

2.52e-061961958754a3613340932563cd8424d775e18b93c3a1aaa
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNS3 PRRX1 ADAMTS2 SLC1A5 PPL THBS2 SMO PLCE1

2.52e-0619619582029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

CD109 ACAN PKD1 MN1 ANK2 SLC1A4 THBS2 AHNAK2

2.71e-0619819589f9dcf23ffb333105263132d87b90095642294cf
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL26A1 ADCY1 MAMDC2 PRRX1 ADAMTS2 THBS2 AHNAK2

9.83e-061691957031465190cd3623a25ef2b868daab8d932c8ff08
ToppCellPericytes-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ALX4 GJA3 PRRX1 NTSR1 THBS2 MYOCD LGR6

1.06e-051711957bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCellThalamus|World / BrainAtlas - Mouse McCarroll V32

FREM3 APOL6 LINGO4 ZFHX3 FHDC1 AHNAK2

1.23e-0511619565ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD109 HMOX1 MYLK4 ANK2 SLC4A3 PPL CD68

1.33e-051771957f7a2e6b5e82f0565f8030696944f33c544233b94
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD109 HMOX1 MYLK4 ANK2 SLC4A3 PPL CD68

1.33e-051771957ef02ee75db36a92dda889efb6fad1193efbc4be4
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

ASXL1 ZNF623 NRXN2 TAF4 TNS3 THBS2 PCMTD2

1.38e-051781957edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

ITGA5 PPFIA2 MAGEC3 THBS2 ZFHX3 MYOCD LGR6

1.48e-051801957d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-5|TCGA-Colorectal / Sample_Type by Project: Shred V9

NARS1 PCYOX1L NECTIN4 PKP2 ATP2C1 PITPNM3 ZNF488

1.53e-0518119578fcc9e77fee7c248df26b6c59b10e672242e2084
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRTC3 GPER1 SLC4A3 SIX5 ZFHX3 MYOCD PLCE1

1.71e-05184195794748f63947db79a6b4540e3090a63689fdd9452
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRTC3 GPER1 SLC4A3 SIX5 ZFHX3 MYOCD PLCE1

1.71e-051841957819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD109 MN1 GPER1 PPL LEFTY1 THBS2 LGR6

1.83e-051861957b58db5abdd3e9f0214b198c3cbd09b0b3c321eab
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ZBTB7A SEMA6B ADAMTS2 PPFIA2 PCLO CD93 ZFHX3

1.83e-05186195723b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD109 MN1 GPER1 PPL LEFTY1 THBS2 LGR6

1.83e-051861957cd6502bbf9dce318fdbb4965d49df8951e5f795c
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 HMOX1 ZBTB7A RANBP2 CREBBP ANKRD11 SON

1.89e-051871957663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD109 MN1 GPER1 PPL LEFTY1 THBS2 LGR6

1.89e-0518719578bd635abdee5d5a12a3f7bf74eab4282e8e40741
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD109 MN1 GPER1 PPL LEFTY1 THBS2 LGR6

1.89e-0518719573cb8cd7f7a4306ff74d1f7f9964014008ec1c6a0
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic|GI_large-bowel / Manually curated celltypes from each tissue

HAPLN4 MAMDC2 HOMER3 SEMA6B ADAMTS2 CD68 ZFHX3

1.96e-051881957d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD109 CD320 ITGA5 RAPGEF3 CD93 KANK3 AGRN

1.96e-0518819570026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes|GI_large-bowel / Manually curated celltypes from each tissue

HAPLN4 MAMDC2 HOMER3 SEMA6B ADAMTS2 CD68 ZFHX3

1.96e-0518819570bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

ASXL1 WWC3 TNS3 ZNF629 COL18A1 THBS2 PCMTD2

1.96e-05188195714bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADCY1 ACAN PRRX1 ZFHX3 MYOCD LGR6 PLCE1

2.03e-051891957975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYCBP2 ZBTB7A PTPRN2 KMT2A CARMIL2 AMER3 SPTBN4

2.10e-051901957416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellfacs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD109 GPER1 FREM3 THBS2 APOL6 MYOCD LGR6

2.10e-051901957c7bd087f36321cec61b98657433b4d19d135791f
ToppCellNS-critical-d_16-33-Myeloid-Non-resident_Macrophage|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLAMF8 RNF130 ITGA5 TNS3 SEMA6B ADAMTS2 CD68

2.10e-0519019574fe9654a9b449ef49ca10b973ac4378dab34cb53
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADCY1 ACAN THBS2 ZFHX3 MYOCD LGR6 PLCE1

2.10e-05190195773d94fbae92029745989a8712eed8b99fd84c193
ToppCellfacs-Lung-nan-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD109 GPER1 FREM3 THBS2 APOL6 MYOCD LGR6

2.10e-051901957834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

GAPVD1 MYCBP2 KIF13B OSTM1 NSD1 SLC1A5 ARID2

2.17e-0519119579454f642c3621370fa23640b631301346b300950
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRS1 ACAN ANK2 GALNT9 ZFHX3 MYOCD LGR6

2.17e-0519119577853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYLK4 PRRX1 ADAMTS2 COL18A1 APOL6 ZFHX3 MYOCD

2.24e-05192195726d9207e72bbef5e0046de511e2c9ff752b726f3
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ALX4 MAMDC2 ACAN COL18A1 ZFHX3 MYOCD PLCE1

2.24e-051921957a7d08416f07f29ad920168a3b52ddf992f263bf4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALX4 MN1 GPER1 SLC1A5 ZFHX3 MYOCD PLCE1

2.32e-05193195718e11d515147accef9aee26e934b358b445e18e2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALX4 MN1 GPER1 SLC1A5 ZFHX3 MYOCD PLCE1

2.32e-051931957ce3e8cf30b7b4d5c7a8f3d64c21d81d2c3cab5c1
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DOK6 IRS1 PRRX1 PPFIA2 COL18A1 THBS2 MYOCD

2.40e-0519419572d66091097e106c7bee22e5281f50724700bdf8d
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLAMF8 IL10RA RNF130 HMOX1 HSPA6 CD93 CD68

2.40e-051941957ad72be9f6871b334e1f477d868c15e7792fadea5
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CD109 CD320 ITGA5 RAPGEF3 CD93 KANK3 AGRN

2.48e-051951957cc3d6f98d310e8840ff497d7258c5ccf54e6c624
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACAN MYLK4 PRRX1 ADAMTS2 APOL6 ZFHX3 MYOCD

2.48e-05195195743d372373367b71243c6ea958aedccde4478618f
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 PTPRN2 KMT2A PCLO NSD1 ANKRD11 SON

2.48e-0519519573e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 DDB1 PTPRN2 KMT2A PCLO ANKRD11 SON

2.48e-0519519577796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD320 ITGA5 SCGB3A1 RAPGEF3 SEMA6B CD93 KANK3

2.56e-051961957ae46d4b00be92e64e46252dcc156161b171eded4
ToppCellMonocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SLAMF8 RNF130 HMOX1 AP1B1 TNS3 CD93 CD68

2.56e-051961957ab0a8f5f388c9794d7f41f99fb0a5f2fd6fff6b3
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RNF130 AP1B1 TNS3 ADAMTS2 CD93 CD68 ZFHX3

2.56e-05196195728e9e191361966df3a9bd48450090577aa72a999
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CD109 MAMDC2 ACAN ADAMTS2 NHSL1 THBS2 AHNAK2

2.56e-05196195724d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellnormal_Lung-Myeloid_cells-mo-Mac|normal_Lung / Location, Cell class and cell subclass

SLAMF8 RNF130 HMOX1 AP1B1 MAMDC2 CD93 ZFHX3

2.56e-0519619574d3a3264b3d781139899448cde3b7a4f214ca14d
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

SLAMF8 IREB2 AP1B1 SH2B3 SLC4A3 RAB11FIP4 AHNAK2

2.56e-05196195709d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCelldistal-3-mesenchymal-Fibromyocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VWA5B2 IRS1 LEFTY2 THBS2 GALNT9 MYOCD LGR6

2.73e-051981957dc93886439a378a0c71e99acb8081bfb6b6d467b
ToppCellFibroblasts-DKK3+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CD109 MAMDC2 PRRX1 ANK2 ADAMTS2 THBS2 AHNAK2

2.73e-0519819574f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_pulmonary_venous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CD109 ITGA5 RAPGEF3 GPER1 PRX CD93 KANK3

2.73e-0519819576fd984da5d2c419aeb34c8cbd8a00440e2f820a5
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNF130 HMOX1 ITGA5 HOMER3 SEMA6B CD93 CD68

2.73e-05198195794e2567f057b2c455a9656b121321a28e7cb1d2b
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

DOK6 MAMDC2 PRRX1 ANK2 ADAMTS2 GLIS3 THBS2

2.73e-051981957df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellHealthy_donor-Non-classical_Monocyte|World / disease group, cell group and cell class (v2)

RNF130 HMOX1 SCGB3A1 HSPA6 SH2B3 RIN1 CD68

2.73e-0519819578a97c8b2a43e6d1e669ce18752841e2006744bd9
ToppCellNS-moderate-d_16-33-Myeloid-Non-resident_Macrophage|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CD109 HMOX1 ITGA5 TNS3 SEMA6B CD93 CD68

2.73e-05198195711a7a553de6786c1e8288251ba0d5c898505c158
ToppCellHealthy_donor-Non-classical_Monocyte|Healthy_donor / disease group, cell group and cell class (v2)

RNF130 HMOX1 SCGB3A1 HSPA6 SH2B3 RIN1 CD68

2.73e-051981957d4eae333fa100db3ea2d4cbe7a1d6ab14816f0e2
ToppCell5'-Adult-SmallIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDHR2 SLC25A37 DMBT1 HSD17B2 NR0B2 CD68 PPP1R16A

2.82e-051991957a5fffe381be1ba7d192b68d1d3937ce47663658e
ToppCellSevere-Myeloid-Macrophages-FCN1+SPP1+|Severe / Condition, Lineage, Cell class and cell subclass

SLAMF8 RNF130 HMOX1 ITGA5 HSPA6 TNS3 CD68

2.82e-051991957fa22f3b7e058a6be604bdbefd4ec724e783b46d8
ToppCellcontrol-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SPAST HSPA1L SEMA6B CALCOCO1 PCMTD2 LGR6 ZNF554

2.82e-05199195750e2da35edff1aadef939cfbd4549f73c1a07717
ToppCellcontrol-unassigned|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SPAST HSPA1L SEMA6B CALCOCO1 PCMTD2 LGR6 ZNF554

2.82e-0519919575db7c8089172ac8e796613b3cef618d87007a0ab
ToppCellmoderate-Myeloid-Non-resident_Macrophage|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CD109 HMOX1 ITGA5 TNS3 SEMA6B CD93 CD68

2.82e-051991957614c1e788d89310e78984241977941beed8d12dc
ToppCell(2)_Fibroblasts-(24)_Fibro-5|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CD109 MAMDC2 MN1 PRRX1 ADAMTS2 THBS2 AHNAK2

2.82e-0519919576c0354f57883330c685a8d9d5d3014ace7eca584
ToppCellcellseq-Immune-Immune_Myeloid-IM|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLAMF8 IL10RA RNF130 HMOX1 AP1B1 SH2B3 CD68

2.82e-051991957b3267d5a7ae0461f5e9e6a3ab6783317a8c42506
ToppCellcellseq-Immune-Immune_Myeloid-IM-IM|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLAMF8 IL10RA RNF130 HMOX1 AP1B1 SH2B3 CD68

2.82e-05199195701dacee8bb392639d475be3cb27ba3eeff1e57f1
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

SUOX CANT1 CHD7 SLC1A4 ATP2C1 CHTF18 PCNT

2.91e-052001957118321ac443feb42aee171baccfc4610f00a8822
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLAMF8 IL10RA RNF130 AP1B1 HSPA6 SH2B3 CD93

2.91e-052001957ad52b38df5c71f28829b04cd0e6b97f0f9f7610a
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DOK6 ACAN COL18A1 ZFHX3 MYOCD LGR6 PLCE1

2.91e-052001957c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD109 CD320 ITGA5 RAPGEF3 CD93 KANK3 AGRN

2.91e-05200195790061284a80d29a4ca6078f578e13d32b8cc80e1
ToppCell(61)_LYVE1_Macrophage|World / shred on Cell_type and subtype

SLAMF8 RNF130 HMOX1 MAMDC2 ADAMTS2 CD93 CD68

3.51e-052061957711e961a9a03bfd2f0958bd14f25f7f207a2f2b5
ToppCell(50)_cDC2|World / shred on Cell_type and subtype

SLAMF8 RNF130 NRXN2 GPER1 SLC4A3 CD93 CD68

3.51e-052061957d519adeb8290fcce107e81a439ba3bf1e231b55b
Diseasebody fat distribution

SLC25A37 SLC2A10 ACAN OS9 ADAMTS2 NSD1 POMGNT1 BCDIN3D THBS2 PLCE1

7.87e-0720218910EFO_0004341
DiseaseProstatic Neoplasms

RNF130 SLC39A1 IRS1 HMOX1 CASZ1 BAP1 ZBTB7A KMT2A PRRX1 NAGK CHD7 NR3C1 CREBBP PPL ARID2 ZFHX3

2.53e-0661618916C0033578
DiseaseMalignant neoplasm of prostate

RNF130 SLC39A1 IRS1 HMOX1 CASZ1 BAP1 ZBTB7A KMT2A PRRX1 NAGK CHD7 NR3C1 CREBBP PPL ARID2 ZFHX3

2.53e-0661618916C0376358
Diseasemyelofibrosis (is_implicated_in)

ASXL1 KMT2A SH2B3

1.41e-0581893DOID:4971 (is_implicated_in)
DiseaseAcute Cerebrovascular Accidents

CASZ1 PAOX ANK2 SH2B3 ZFHX3

2.51e-05541895C0751956
DiseaseCerebrovascular accident

CASZ1 PAOX ANK2 SH2B3 ZFHX3

4.92e-05621895C0038454
Diseasemyelodysplastic syndrome (implicated_via_orthology)

ASXL1 BAP1 CREBBP

1.11e-04151893DOID:0050908 (implicated_via_orthology)
DiseaseLeukemia, Myelocytic, Acute

ZBTB7A KMT2A MN1 SH2B3 NSD1 CREBBP AGRN

1.32e-041731897C0023467
Diseasephenylketonuria (implicated_via_orthology)

HNF1A DUOX2

2.43e-0441892DOID:9281 (implicated_via_orthology)
DiseaseHearing abnormality

APC2 AP1B1

2.43e-0441892C4025860
DiseaseSotos' syndrome

APC2 NSD1

2.43e-0441892C0175695
DiseaseCraniosynostosis

ALX4 MN1 TCF12

2.72e-04201893C0010278
Diseasecortical thickness

VWA5B2 COL26A1 MYCBP2 LGR4 RABGAP1 ALX4 PKD1 KMT2A ADAMTS2 ESPNL GLIS3 CHD7 NHSL1 COL18A1 CD68 FAM53B RAB11FIP4 PLCE1

3.09e-04111318918EFO_0004840
Diseasestroke

CASZ1 TTBK1 ANK2 SH2B3 ADAMTS2 ZFHX3

3.42e-041441896EFO_0000712
DiseaseObesity

IRS1 HMOX1 RAPGEF3 NR0B2 CD68 ZFHX3 FGGY

3.71e-042051897C0028754
DiseaseWeaver syndrome

KMT2A NSD1

4.03e-0451892C0265210
DiseasePolycystic Kidney - body part

PKD1 GLIS3

4.03e-0451892C1567435
Diseasesphingomyelin measurement

CD320 RAPGEF3 FAM234B HNF1A TNRC6C KCNH3 KANK3 ANKRD11

4.50e-042781898EFO_0010118
DiseaseParoxysmal atrial fibrillation

CASZ1 PKP2 PRRX1 NR3C1 ZFHX3 MYOCD

5.23e-041561896C0235480
Diseasefamilial atrial fibrillation

CASZ1 PKP2 PRRX1 NR3C1 ZFHX3 MYOCD

5.23e-041561896C3468561
DiseasePersistent atrial fibrillation

CASZ1 PKP2 PRRX1 NR3C1 ZFHX3 MYOCD

5.23e-041561896C2585653
DiseaseAtrial Fibrillation

CASZ1 PKP2 PRRX1 NR3C1 ZFHX3 MYOCD

5.98e-041601896C0004238
Diseaseprotein-glutamine gamma-glutamyltransferase e measurement

DLG5 NR0B2 HNF1A NFE2L3

6.01e-04601894EFO_0020690
Diseasepappalysin-1 measurement

SEMA6B CHD7

6.02e-0461892EFO_0802845
Diseaseepisodic ataxia type 6 (implicated_via_orthology)

SLC1A4 SLC1A5

6.02e-0461892DOID:0050994 (implicated_via_orthology)
DiseaseEndogenous Hyperinsulinism

IRS1 HMOX1 CD68

6.03e-04261893C1257963
DiseaseExogenous Hyperinsulinism

IRS1 HMOX1 CD68

6.03e-04261893C1257964
DiseaseCompensatory Hyperinsulinemia

IRS1 HMOX1 CD68

6.03e-04261893C1257965
DiseaseHyperinsulinism

IRS1 HMOX1 CD68

7.53e-04281893C0020459
Diseasesexual dimorphism measurement

TACO1 GAPVD1 LGR4 SLC25A37 ACAN PKD1 NLRC5 PLAG1 HNF1A NSD1 NR3C1 KCNK7 KANK3 ANKRD11 FAM53B ZFHX3 RAB11FIP4

8.00e-04110618917EFO_0021796
Diseasecystatin C measurement

ARHGEF16 ZBTB7A HNF1A TFAP2D SH2B3 NSD1 BCDIN3D CD93 ANKRD11

1.20e-034021899EFO_0004617
DiseaseAcute Myeloid Leukemia, M1

ZBTB7A KMT2A MN1 NSD1 AGRN

1.29e-031251895C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

ZBTB7A KMT2A MN1 NSD1 AGRN

1.29e-031251895C1879321
Diseaseprimary bacterial infectious disease (implicated_via_orthology)

DUOX2 SMO

1.43e-0391892DOID:0050338 (implicated_via_orthology)
DiseaseSarcomatoid Renal Cell Carcinoma

PIDD1 BAP1 HNF1A SPTBN4 PRCC

1.43e-031281895C1266043
DiseaseChromophobe Renal Cell Carcinoma

PIDD1 BAP1 HNF1A SPTBN4 PRCC

1.43e-031281895C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

PIDD1 BAP1 HNF1A SPTBN4 PRCC

1.43e-031281895C1266044
DiseasePapillary Renal Cell Carcinoma

PIDD1 BAP1 HNF1A SPTBN4 PRCC

1.43e-031281895C1306837
DiseaseRenal Cell Carcinoma

PIDD1 BAP1 HNF1A SPTBN4 PRCC

1.43e-031281895C0007134
DiseaseInflammatory Bowel Diseases

SLAMF8 IL10RA APC2

1.46e-03351893C0021390
Diseasetestosterone measurement

DENND4A WDR81 SLC25A37 TTBK1 TAF4 HSD17B2 TNS3 HNF1A TCF12 ANK2 ZNF629 GLIS3 CHD7 NR3C1 CD68 ZFHX3 MYOCD ARID3C

1.47e-03127518918EFO_0004908
DiseaseDisproportionate short stature

NKX3-2 CANT1 ACAN PCNT

1.53e-03771894C0878659
Diseasedentate gyrus volume measurement

RABGAP1 FAM53B FGGY

1.99e-03391893EFO_0010083
Diseaseacute myeloid leukemia (is_implicated_in)

ASXL1 KMT2A NSD1 CREBBP

2.11e-03841894DOID:9119 (is_implicated_in)
Diseasethyrotoxic periodic paralysis

ZFHX3 FHDC1

2.16e-03111892MONDO_0019201
DiseaseCongenital small ears

NKX3-2 CHD7 SIX5

2.31e-03411893C0152423
Diseaseretinitis pigmentosa (is_implicated_in)

FSCN2 NRL POMGNT1

2.31e-03411893DOID:10584 (is_implicated_in)
DiseaseClear Cell Meningioma

BAP1 SMO

2.58e-03121892C0431121
DiseaseIntraventricular Meningioma

BAP1 SMO

2.58e-03121892C1334271
DiseaseBenign Meningioma

BAP1 SMO

2.58e-03121892C0281784
Diseasecraniosynostosis (is_implicated_in)

ALX4 TCF12

2.58e-03121892DOID:2340 (is_implicated_in)
DiseaseIntraorbital Meningioma

BAP1 SMO

2.58e-03121892C1334261
DiseaseOlfactory Groove Meningioma

BAP1 SMO

2.58e-03121892C1335107
DiseaseAngioblastic Meningioma

BAP1 SMO

2.58e-03121892C1527197
Diseasebasal cell carcinoma (is_implicated_in)

BAP1 SMO

2.58e-03121892DOID:2513 (is_implicated_in)
DiseaseMeningiomas, Multiple

BAP1 SMO

2.58e-03121892C0205834
DiseaseXanthomatous Meningioma

BAP1 SMO

2.58e-03121892C0457190
DiseaseAngiomatous Meningioma

BAP1 SMO

2.58e-03121892C0334608
DiseasePsammomatous Meningioma

BAP1 SMO

2.58e-03121892C0334607
DiseaseFibrous Meningioma

BAP1 SMO

2.58e-03121892C0334606
DiseaseMeningothelial meningioma

BAP1 SMO

2.58e-03121892C0334605
DiseaseHemangioblastic Meningioma

BAP1 SMO

2.58e-03121892C0334609
DiseaseTransitional Meningioma

BAP1 SMO

2.58e-03121892C0334611
DiseaseHemangiopericytic Meningioma

BAP1 SMO

2.58e-03121892C0334610
DiseaseSpinal Meningioma

BAP1 SMO

2.58e-03121892C0347515
DiseaseIntracranial Meningioma

BAP1 SMO

2.58e-03121892C0349604
DiseasePapillary Meningioma

BAP1 SMO

2.58e-03121892C3163622
DiseaseMalignant Meningioma

BAP1 SMO

2.58e-03121892C0259785
Diseaseacute myeloid leukemia (implicated_via_orthology)

KMT2A CREBBP

2.58e-03121892DOID:9119 (implicated_via_orthology)
DiseaseSphenoid Wing Meningioma

BAP1 SMO

2.58e-03121892C1565951
DiseasePosterior Fossa Meningioma

BAP1 SMO

2.58e-03121892C1565950
DiseaseParasagittal Meningioma

BAP1 SMO

2.58e-03121892C0751304
DiseaseCerebral Convexity Meningioma

BAP1 SMO

2.58e-03121892C0751303
DiseaseMicrocystic meningioma

BAP1 SMO

2.58e-03121892C1384408
DiseaseSecretory meningioma

BAP1 SMO

2.58e-03121892C1384406
Diseasevital capacity

IL11 LGR4 CASZ1 SLC2A10 ZBTB7A ACAN PLAG1 PRRX1 PCLO ZNF629 GLIS3 CHD7 NR3C1 KCNH3 THBS2 ZFHX3 PLCE1

2.60e-03123618917EFO_0004312
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

PIDD1 BAP1 HNF1A SPTBN4 PRCC

2.70e-031481895C0279702
DiseaseDiabetes, Autoimmune

HNF1A SH2B3 GLIS3

2.82e-03441893C0205734
DiseaseBrittle diabetes

HNF1A SH2B3 GLIS3

2.82e-03441893C0342302
DiseaseDiabetes Mellitus, Sudden-Onset

HNF1A SH2B3 GLIS3

2.82e-03441893C4554117
DiseaseDiabetes Mellitus, Ketosis-Prone

HNF1A SH2B3 GLIS3

2.82e-03441893C3837958
Diseaseeye colour measurement

GAPVD1 MYCBP2 DMBT1 TNS3 CD93 MYOCD

2.90e-032181896EFO_0009764
Diseasenasopharyngeal neoplasm

IRS1 KMT2A PPFIA2 PCLO ZFHX3

2.94e-031511895EFO_0004252
DiseaseDiabetes Mellitus, Insulin-Dependent

HNF1A SH2B3 GLIS3

3.01e-03451893C0011854
Diseasebrain measurement, neuroimaging measurement

VWA5B2 COL26A1 RABGAP1 ALX4 GLIS3 NHSL1 COL18A1 LRCH4 FAM53B ZFHX3

3.02e-0355018910EFO_0004346, EFO_0004464
DiseaseLeishmaniasis, Visceral

IL10RA HMOX1

3.04e-03131892C0023290
DiseaseCongenital Hypothyroidism

GLIS3 DUOX2

3.04e-03131892C0010308
DiseaseNeurodevelopmental Disorders

SPAST KMT2A ANK2 ANKRD11

3.05e-03931894C1535926
Diseaseneutrophil count

DENND4A MYCBP2 CASZ1 PKD1 NLRC5 TNS3 HNF1A PRRX1 SH2B3 NSD1 POU2F1 CHD7 CREBBP PRCC ANKRD11 FAM53B FGGY PCNT

3.49e-03138218918EFO_0004833
Diseasemalignant pleural mesothelioma (is_marker_for)

BAP1 SMO

3.53e-03141892DOID:7474 (is_marker_for)
Diseasereaction time measurement

DOK6 ZBTB7A PTPRN2 NAGK TFAP2D SH2B3 ADAMTS2 TNRC6C PITPNM3 ZFHX3 PPP1R16A

3.60e-0365818911EFO_0008393
Diseasecoronary artery disease (is_implicated_in)

IRS1 HMOX1 HNF1A NR3C1

3.96e-031001894DOID:3393 (is_implicated_in)
DiseaseAdenoid Cystic Carcinoma

HOMER3 NSD1 CREBBP SON

3.96e-031001894C0010606
Diseasehepatoblastoma (is_marker_for)

ZFHX3 SMO

4.06e-03151892DOID:687 (is_marker_for)
Diseaseanemia (implicated_via_orthology)

IREB2 SLC4A3

4.06e-03151892DOID:2355 (implicated_via_orthology)
Diseasediastolic blood pressure, systolic blood pressure

GAPVD1 PIDD1 ADCY1 CASZ1 ACAN ANK2 THBS2 FAM53B ZFHX3 MYOCD FGGY

4.12e-0367018911EFO_0006335, EFO_0006336
Diseasecholesterol to total lipids in small VLDL percentage

NLRC5 KCNK7 NFE2L3

4.30e-03511893EFO_0022242
DiseaseHypermetropia

PTPRN2 CHD7 ANKRD11 AGRN

4.40e-031031894HP_0000540
Diseasetyrosine measurement

TTBK1 SEMA6B HNF1A OSTM1

4.56e-031041894EFO_0005058
DiseaseDiabetic Angiopathies

HMOX1 THBS2

4.62e-03161892C0011875

Protein segments in the cluster

PeptideGeneStartEntry
QDLATPLESGAGARG

ALX4

71

Q9H161
EGPGLDGLCQDLLDS

AMER3

206

Q8N944
PADTLLLGDGDAGSL

CHTF18

611

Q8WVB6
ALEGSLDAGLEPNGS

SLC4A3

861

P48751
GLAAAEPTANGGLAL

SLC1A5

11

Q15758
SLIGGAASLDPGALG

SLC1A5

111

Q15758
GVGLALALQPGAASA

SLC1A5

146

Q15758
GPLENSFLDGSRGLS

ANKRD11

2096

Q6UB99
LDGSLSLGAEPGSLL

CASZ1

1616

Q86V15
PGSLLFLQSAAAGLG

CASZ1

1626

Q86V15
LALAPATGGGSLLLS

APOL6

96

Q9BWW8
PLDASGGSTLLNLDF

AFTPH

816

Q6ULP2
ERLDGPLNLAGSGIS

ARID3C

351

A6NKF2
GPILGLDVGCNSGDL

BCDIN3D

66

Q7Z5W3
LDLSGNPGALGASED

CARMIL2

341

Q6F5E8
LSQRLGAGAAAPEGE

CT47B1

171

P0C2W7
VLGESPSGTDGLNLD

AGRN

1476

O00468
LLLLLTQPGAGTGAD

CD93

11

Q9NPY3
SELRLDAGGNPASGL

ARHGEF16

21

Q5VV41
LISNGPSLELGENGA

ARID2

1321

Q68CP9
LGLLNSGNLVPDAAS

CREBBP

51

Q92793
PGALSGSADGQLSVL

BAP1

426

Q92560
LGAPIGSGLSDLFDL

AP1B1

691

Q10567
AASGGNPDAVALLLE

ASB14

256

A6NK59
ALVDLGVLSDPGSGL

DEXI

66

O95424
EGSSQGALLLGQAPE

DMRTC1;

41

Q5HYR2
GLGGLLNNPLSAATG

CHD7

2811

Q9P2D1
ALASGPELGQLTFLG

ATP2C1

526

P98194
TVGLTDGLGDASQLP

ASXL1

736

Q8IXJ9
LGGPQALDTGASLDS

ADAMTS2

221

O95450
PSLGLAAAGADDLQG

TFAP2D

166

Q7Z6R9
TGLSADLNNGSLVGP

DENND4A

71

Q7Z401
VPLRSLGLSLSGGDQ

NAGK

66

Q9UJ70
LLGLLTSDKPLQGDG

RANBP2

1066

P49792
NGDSLLGLPEGALIS

NSD1

586

Q96L73
LSGGQGQSEDSDPLL

RBSN

446

Q9H1K0
DGGLGGLFLPEDKSL

RAB11FIP4

176

Q86YS3
SALGDLAGDNSLGLE

RNF130

341

Q86XS8
LQFLPGENADSLGLS

IREB2

891

P48200
SLPAGAQEALSDGLQ

PTPRN2

486

Q92932
NGTGLELLGGPSLRS

KCNH3

436

Q9ULD8
EAGQRGSALGDLAPS

LRCH4

261

O75427
QALQLAGALDLPAGS

MAMDC2

11

Q7Z304
EFLPALSLQSGALDG

ANK2

2186

Q01484
LLGLLAAQGTGNDCP

CD68

11

P34810
SQLDGEGDGPLSNQL

RABGAP1

86

Q9Y3P9
ALGSLSPALEDGKAA

FHDC1

731

Q9C0D6
LLEAGALGPGITDAL

ESPNL

21

Q6ZVH7
SDGLAALQLDGLPSG

ESPNL

416

Q6ZVH7
ALQLDGLPSGDIDGL

ESPNL

421

Q6ZVH7
ASPGAALTGEQLLGS

LEFTY1

16

O75610
LSGSPGLQLSDLHFG

MAGEC3

91

Q8TD91
LEEALLAPGFGNASG

NTSR1

26

P30989
DNQLTTLPLAGLGGL

LGR6

431

Q9HBX8
TGQTGLPGDSGLLQD

SLC2A10

336

O95528
DGLLQLGPLGSTAFL

GALNT9

506

Q9HCQ5
GLGLGLEAAASPLST

CD320

26

Q9NPF0
ANGNLVPTGTDSGLL

ATXN1L

416

P0C7T5
AGPSGSNGVEALQLL

GAPVD1

601

Q14C86
GGILGQDELALSTLP

KCNK7

281

Q9Y2U2
LLGALLTGSLGPSGN

DUOX2

11

Q9NRD8
LTGSLGPSGNQDALS

DUOX2

16

Q9NRD8
QDGGELTSPALGLAS

HOMER3

121

Q9NSC5
GANLLLSASPDFGDI

CANT1

316

Q8WVQ1
EGGLLCGEGPAASLQ

NHSL1

1566

Q5SYE7
GAPGNSLCSLDGELD

FAM53B

401

Q14153
SAGALGALQLPGVLT

IL11

81

P20809
SLEGEGLPEGLAAAA

PCLO

6

Q9Y6V0
LDLQPGLSFLNLGSG

PCMTD2

76

Q9NV79
LTALLAAAAAGGDAP

PCYOX1L

11

Q8NBM8
PGDASDLQGRQLLAG

PPL

496

O60437
SVGPGLANNSALLGA

COL18A1

311

P39060
GSQGGGDLSPLELAD

FAM234B

141

A2RU67
LLQDELLFLGGPASS

NFE2L3

41

Q9Y4A8
QLGAGEALGLSPEEA

NRL

81

P54845
QDLGLGSPAQLSSSG

TCF12

136

Q99081
LLGSQGLRGATADPL

NRXN2

191

Q9P2S2
VLGLLEAAGALSPGE

DLG5

26

Q8TDM6
LLSGLSPFLGDNDAE

MYLK4

296

Q86YV6
ELAELPNGLGETRGS

HNF1A

56

P20823
LDVAPLSLGLETAGG

HSPA1L

396

P34931
LALGLLGSAGPSGAA

LGR4

11

Q9BXB1
GDDNLTSLGTLNFPG

NR3C1

371

P04150
VAAPGGLLGSFNSDL

IL10RA

551

Q13651
EDLSLSLLQGGGLGP

OSTM1

56

Q86WC4
AELAAHSSLLGGPQG

IRS1

1051

P35568
ILLEEPSSSGGSGQL

NR0B2

121

Q15466
LDDAGAGLALSTAPA

PCNT

1191

O95613
LNGGSVPSELDGLDS

MYOCD

501

Q8IZQ8
GPGGALSLAQALDGS

NLRC5

1701

Q86WI3
LVGSASGDLDLGKLP

ACAN

1596

P16112
GGALLSLNPGTLSGA

POU2F1

611

P14859
AEHGLLLGQPSSGAA

NOL7

31

Q9UMY1
LDAGLAELAPLQGQG

NUTM1

636

Q86Y26
NGDGLDDLLVGAPLL

ITGA5

336

P08648
GALGGAEDSLLASPA

NKX3-2

61

P78367
LLATLDQVAAGAGDP

FCSK

586

Q8N0W3
DPFADLGDLSSGLQG

GAK

1081

O14976
LAGALALAELLGAPG

ADCY1

71

Q08828
GAPAGGQLSLLGSDV

APC2

2216

O95996
GQLSLLGSDVDGPSL

APC2

2221

O95996
GQDPSGLQLGLTEAL

CENPB

351

P07199
GDVLGPSINGLASLI

CD109

901

Q6YHK3
NGTFLLSLGGPDAEA

CDHR2

401

Q9BYE9
ELDNLGLDSFSSGPG

BMP10

281

O95393
ILGEDLAGPSAGAAA

DOCK8-AS1

51

Q5T8R8
LNDISLGEPDLLAAG

DOK6

116

Q6PKX4
SFDLLGNPLENILGG

DNAJB3

111

Q8WWF6
GASLGNGLTPEAARD

FGGY

231

Q96C11
GTLNTGGSLPDLTNL

CRTC3

266

Q6UUV7
RDGAAASLAQGGLLP

ATG9A

586

Q7Z3C6
GSQNGLDLGDLLSLP

GLIS3

86

Q8NEA6
NSGTSLLGPSLLDGN

CRAMP1

1186

Q96RY5
DVGLSAGLQASDLPA

SLC3A2

571

P08195
AGPGAALTEEQLLGS

LEFTY2

16

O00292
SPDGLAAGRSEGALQ

KANK3

271

Q6NY19
SSELLNLGEGLGLDS

KMT2A

2871

Q03164
AQKALDLPSSGEGLA

HMOX1

151

P09601
AELQGDGPGDASLVL

HAPLN4

116

Q86UW8
HLPAGFLSLQGLSGD

KRTAP23-1

46

A1A580
DDGAAAGGALQVPLL

FIGNL2

501

A6NMB9
LDVAPLSLGLETAGG

HSPA6

396

P17066
AEAGAAPLLLDGSGS

GJA3

366

Q9Y6H8
GPESSLALRLVNGGD

DMBT1

356

Q9UGM3
NNAGVLGFPTDGELL

HSD17B2

166

P37059
DALISSPILAGEGGA

PSMD4

181

P55036
QSGGEEANLLLPELG

CALCOCO1

611

Q9P1Z2
GAVSSALGGSAPQLL

PPRC1

696

Q5VV67
LASPEGGSGQDAALR

COL26A1

391

Q96A83
LGDSNGLSPLCAIGL

DDB1

546

Q16531
LPQDIESLTGGLAGS

PPFIA2

81

O75334
GGLPLDTELLDLSGN

LINGO4

56

Q6UY18
RGALTNLPAGLSGLA

PIDD1

111

Q9HB75
GLSLAPLNLGDAETG

PIDD1

771

Q9HB75
AENLLVGAPSGDLQG

PKD1

541

P98161
AVGSTGGDLDLLAQP

PAOX

441

Q6QHF9
LLLGDQPDLIGSLDG

MN1

1016

Q10571
QPDLIGSLDGGAKSD

MN1

1021

Q10571
GGASGLLRADADAPA

FSCN2

471

O14926
LLGPEGQDAGSAGVL

FREM3

271

P0C091
ATLSDALGPGLDAAA

KIF13B

1576

Q9NQT8
GPGAAQTLNGSAALL

TAF4

191

O00268
ALEAGGSSGLEDVLP

RMDN3

226

Q96TC7
GEGAGADEFLPLLSL

RIN1

531

Q13671
SALPSQALGGIASGL

TNRC6C

1046

Q9HCJ0
LQGSSEGTGLSALLP

PRCC

171

Q92733
SLAEDLLGLTDPNGG

TRADD

296

Q15628
ELIGLAPAGGADNLI

NARS1

206

O43776
PLLGNAGLSSLTEGV

PLCE1

921

Q9P212
RGPGGSSLLIEALSN

TACO1

141

Q9BSH4
ALLRSLGSQAGPALG

POMGNT1

191

Q8WZA1
PLLGTALANGTGELS

GPER1

36

Q99527
GGLAGALAAAATTPL

SLC25A37

241

Q9NYZ2
LGSGVSPDLANEDGL

PPP1R16A

91

Q96I34
NGLALGEASSLGPLL

SIX5

346

Q8N196
SLAASHSNLLLGPGG

SHISA7

446

A6NL88
VAAAGLGLGLPAADS

MYCBP2

46

O75592
LEQLGLAGADLAAPG

PKN1

16

Q16512
LGGNDLEVLPDTLGA

SCRIB

181

Q14160
GSDLTALAKDAALGP

SPAST

546

Q9UBP0
DQLLSGFGLEDPGSS

TNS3

426

Q68CZ2
PASLTGGVGSLNLEE

OS9

21

Q13438
NVASALGNLGPEGLG

STK36

1211

Q9NRP7
SDLLGPLGAQADEAG

THAP7

176

Q9BT49
PGAKLDGAQLDGDLS

AHNAK2

1301

Q8IVF2
PQIGSLDDGAGDLSL

PLAG1

386

Q6DJT9
DQLGPTVGSAEGLDL

RAPGEF3

646

O95398
LELDAASGGLLAAFP

SEMA6B

501

Q9H3T3
PAGESADALGELSGL

ZNF488

181

Q96MN9
GADLPGSLSLLESEG

TICRR

1706

Q7Z2Z1
RAPLENGLALSGLNG

TTBK1

976

Q5TCY1
PGSGAQTLQSSDLGL

SLC1A4

141

P43007
PLGIGLGAALAESAG

SLC39A1

251

Q9NY26
TLSLPGAQVAGGELL

PRX

1191

Q9BXM0
DSLNQGASPGGLLDP

SH2B3

336

Q9UQQ2
SASGAAAIALPGLEG

SPCS1

16

Q9Y6A9
LLAADGAELGPGLAL

SPTBN4

1156

Q9H254
LSLELGPLESGDSGN

SLAMF8

86

Q9P0V8
EGLLASGAEGGDLTA

WDR53

21

Q7Z5U6
LLLGDPGRGAASSGN

SMO

21

Q99835
FPLGDGQSLLLADAL

PITPNM3

466

Q9BZ71
GPAAGLEAQLAALGL

SOCS7

51

O14512
LEAQLAALGLGQPAG

SOCS7

56

O14512
QSLGQASLGPTGELA

ZMIZ2

846

Q8NF64
GDTEGNGELGFLLPS

ZBTB9

316

Q96C00
GQGLDDSGNLLSPAP

VWA5B2

791

Q8N398
GAPGGQSLSLSLDDL

SUOX

236

P51687
SRGTLLALEGPGLSQ

THBS2

96

P35442
ALGAAGLDAASPTLL

LCMT2

171

O60294
ALIAGGLGASEEPLN

LCMT2

546

O60294
AQGDSLLGLGDPSLL

ZNF629

546

Q9UEG4
LGELLGNPEGQSLGS

ZNF623

56

O75123
GGRLDSPGNLDTLQA

PRRX1

16

P54821
NVGEAGRSLLESPGL

PRRX1

56

P54821
DLLDLGPGSLSDGLS

PSMB5

26

P28074
LEAGSRLGPDSLALA

TPGS1

241

Q6ZTW0
ASLGALQNLTAGSGP

PKP2

701

Q99959
EAGAGTLANPLGTLN

SCGB3A1

41

Q96QR1
QSGAAGALELLGQPL

SON

611

P18583
GTLAAAPEGLEDAGL

TEX19

101

Q8NA77
GDQLGSSSQASPGLL

WDR81

676

Q562E7
LAQLADSCEGPGLGA

WWC3

481

Q9ULE0
GDGPDVDGLAASTLL

ZBTB7A

306

O95365
QAGLLTPSTLLNLGG

ZFHX3

391

Q15911
GFGENGNLSPALVLS

ZNF554

221

Q86TJ5
NAELTGGVDGPALSL

KIAA1958

216

Q8N8K9
LDLSGNDLSGSQLAP

LRRC14

341

Q15048
GPALEEGQGLTLAAS

NECTIN4

156

Q96NY8